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Network neighborhood for query Sequence : CACB4_HUMAN

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CACB4_HUMAN
SwissProt Accessions	O00305, O60515, Q96L40	Gene names	CACNB4, CACNLB4
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-4 (CAB4) (Calcium channel voltage-dependent subunit beta 4).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CACB4_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	47	Target Neighborhood Hits	47	Shared Neighborhood Hits	47
SwissProt Accessions	O00305, O60515, Q96L40	Gene names	CACNB4, CACNLB4
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-4 (CAB4) (Calcium channel voltage-dependent subunit beta 4).

CACB4_MOUSE
θ value	0 (rank : 2)	NC score	0.999588 (rank : 2)
Query Neighborhood Hits	47	Target Neighborhood Hits	42	Shared Neighborhood Hits	42
SwissProt Accessions	Q8R0S4, Q8BRN6, Q8CAJ9	Gene names	Cacnb4, Cacnlb4
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-4 (CAB4) (Calcium channel voltage-dependent subunit beta 4).

CACB1_MOUSE
θ value	4.85525e-171 (rank : 3)	NC score	0.990393 (rank : 6)
Query Neighborhood Hits	47	Target Neighborhood Hits	46	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R3Z5, O88517, Q7TPF2, Q8R3Z6, Q9EPT9	Gene names	Cacnb1, Cacnlb1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-1 (CAB1) (Calcium channel voltage-dependent subunit beta 1).

CACB1_HUMAN
θ value	6.34118e-171 (rank : 4)	NC score	0.990866 (rank : 5)
Query Neighborhood Hits	47	Target Neighborhood Hits	44	Shared Neighborhood Hits	29
SwissProt Accessions	Q02641, O15331, Q02639, Q02640, Q9C085	Gene names	CACNB1, CACNLB1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-1 (CAB1) (Calcium channel voltage-dependent subunit beta 1).

CACB2_HUMAN
θ value	3.25673e-167 (rank : 5)	NC score	0.980436 (rank : 8)
Query Neighborhood Hits	47	Target Neighborhood Hits	99	Shared Neighborhood Hits	28
SwissProt Accessions	Q08289, O00304, Q8WX81, Q96NZ3, Q96NZ4, Q96NZ5, Q9BWU2, Q9HD32, Q9Y340, Q9Y341	Gene names	CACNB2, CACNLB2, MYSB
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2) (Lambert-Eaton myasthenic syndrome antigen B) (MYSB).

CACB2_MOUSE
θ value	8.02161e-166 (rank : 6)	NC score	0.982113 (rank : 7)
Query Neighborhood Hits	47	Target Neighborhood Hits	94	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CC27, Q8C5J5, Q9CTQ6	Gene names	Cacnb2, Cacnlb2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2).

CACB3_HUMAN
θ value	3.37019e-164 (rank : 7)	NC score	0.991007 (rank : 4)
Query Neighborhood Hits	47	Target Neighborhood Hits	45	Shared Neighborhood Hits	26
SwissProt Accessions	P54284, Q13913	Gene names	CACNB3, CACNLB3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-3 (CAB3) (Calcium channel voltage-dependent subunit beta 3).

CACB3_MOUSE
θ value	6.35588e-163 (rank : 8)	NC score	0.991162 (rank : 3)
Query Neighborhood Hits	47	Target Neighborhood Hits	48	Shared Neighborhood Hits	27
SwissProt Accessions	P54285	Gene names	Cacnb3, Cacnlb3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-3 (CAB3) (Calcium channel voltage-dependent subunit beta 3) (CCHB3).

DLG3_HUMAN
θ value	5.81887e-07 (rank : 9)	NC score	0.229188 (rank : 9)
Query Neighborhood Hits	47	Target Neighborhood Hits	269	Shared Neighborhood Hits	32
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

DLG3_MOUSE
θ value	4.92598e-06 (rank : 10)	NC score	0.221604 (rank : 12)
Query Neighborhood Hits	47	Target Neighborhood Hits	274	Shared Neighborhood Hits	32
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

DLG1_HUMAN
θ value	8.40245e-06 (rank : 11)	NC score	0.222827 (rank : 10)
Query Neighborhood Hits	47	Target Neighborhood Hits	290	Shared Neighborhood Hits	32
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

DLG1_MOUSE
θ value	1.09739e-05 (rank : 12)	NC score	0.222089 (rank : 11)
Query Neighborhood Hits	47	Target Neighborhood Hits	285	Shared Neighborhood Hits	32
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

DLG4_MOUSE
θ value	0.000158464 (rank : 13)	NC score	0.199026 (rank : 15)
Query Neighborhood Hits	47	Target Neighborhood Hits	282	Shared Neighborhood Hits	33
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_HUMAN
θ value	0.00020696 (rank : 14)	NC score	0.198609 (rank : 16)
Query Neighborhood Hits	47	Target Neighborhood Hits	286	Shared Neighborhood Hits	33
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG2_MOUSE
θ value	0.00298849 (rank : 15)	NC score	0.195875 (rank : 17)
Query Neighborhood Hits	47	Target Neighborhood Hits	271	Shared Neighborhood Hits	32
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

MPP6_MOUSE
θ value	0.00509761 (rank : 16)	NC score	0.210735 (rank : 13)
Query Neighborhood Hits	47	Target Neighborhood Hits	187	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

DLG2_HUMAN
θ value	0.0148317 (rank : 17)	NC score	0.183661 (rank : 20)
Query Neighborhood Hits	47	Target Neighborhood Hits	279	Shared Neighborhood Hits	32
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

MPP6_HUMAN
θ value	0.0148317 (rank : 18)	NC score	0.207132 (rank : 14)
Query Neighborhood Hits	47	Target Neighborhood Hits	180	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

LAMA4_HUMAN
θ value	0.0330416 (rank : 19)	NC score	0.021196 (rank : 69)
Query Neighborhood Hits	47	Target Neighborhood Hits	708	Shared Neighborhood Hits	6
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

MPP5_HUMAN
θ value	0.0563607 (rank : 20)	NC score	0.193218 (rank : 18)
Query Neighborhood Hits	47	Target Neighborhood Hits	231	Shared Neighborhood Hits	31
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPP5_MOUSE
θ value	0.0736092 (rank : 21)	NC score	0.191242 (rank : 19)
Query Neighborhood Hits	47	Target Neighborhood Hits	226	Shared Neighborhood Hits	31
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

CSKP_MOUSE
θ value	0.0961366 (rank : 22)	NC score	0.068442 (rank : 37)
Query Neighborhood Hits	47	Target Neighborhood Hits	1027	Shared Neighborhood Hits	32
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

CSKP_HUMAN
θ value	0.125558 (rank : 23)	NC score	0.069465 (rank : 36)
Query Neighborhood Hits	47	Target Neighborhood Hits	1022	Shared Neighborhood Hits	31
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

MPP2_HUMAN
θ value	0.163984 (rank : 24)	NC score	0.154657 (rank : 23)
Query Neighborhood Hits	47	Target Neighborhood Hits	173	Shared Neighborhood Hits	26
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

SRC_HUMAN
θ value	0.47712 (rank : 25)	NC score	0.007332 (rank : 76)
Query Neighborhood Hits	47	Target Neighborhood Hits	1058	Shared Neighborhood Hits	25
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

EM55_MOUSE
θ value	0.62314 (rank : 26)	NC score	0.174632 (rank : 22)
Query Neighborhood Hits	47	Target Neighborhood Hits	221	Shared Neighborhood Hits	31
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

EM55_HUMAN
θ value	1.06291 (rank : 27)	NC score	0.176427 (rank : 21)
Query Neighborhood Hits	47	Target Neighborhood Hits	228	Shared Neighborhood Hits	33
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

MPP2_MOUSE
θ value	1.06291 (rank : 28)	NC score	0.145623 (rank : 25)
Query Neighborhood Hits	47	Target Neighborhood Hits	189	Shared Neighborhood Hits	26
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

NPHP1_MOUSE
θ value	1.06291 (rank : 29)	NC score	0.097774 (rank : 31)
Query Neighborhood Hits	47	Target Neighborhood Hits	267	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

MYO1E_HUMAN
θ value	1.38821 (rank : 30)	NC score	0.013248 (rank : 73)
Query Neighborhood Hits	47	Target Neighborhood Hits	293	Shared Neighborhood Hits	19
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

TS101_HUMAN
θ value	3.0926 (rank : 31)	NC score	0.060324 (rank : 42)
Query Neighborhood Hits	47	Target Neighborhood Hits	359	Shared Neighborhood Hits	8
SwissProt Accessions	Q99816, Q9BUM5	Gene names	TSG101
Domain Architecture
Description	Tumor susceptibility gene 101 protein.

CBX2_HUMAN
θ value	4.03905 (rank : 32)	NC score	0.009049 (rank : 74)
Query Neighborhood Hits	47	Target Neighborhood Hits	264	Shared Neighborhood Hits	2
SwissProt Accessions	Q14781, Q9BTB1	Gene names	CBX2
Domain Architecture	No domain graphic available
Description	Chromobox protein homolog 2.

PDZD6_HUMAN
θ value	5.27518 (rank : 33)	NC score	0.035920 (rank : 67)
Query Neighborhood Hits	47	Target Neighborhood Hits	81	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ULD6, Q4W5I8, Q86V55	Gene names	PDZD6, KIAA1284, PDZK6
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 6.

PTK6_MOUSE
θ value	5.27518 (rank : 34)	NC score	0.007121 (rank : 77)
Query Neighborhood Hits	47	Target Neighborhood Hits	1026	Shared Neighborhood Hits	26
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

T106C_HUMAN
θ value	5.27518 (rank : 35)	NC score	0.016604 (rank : 72)
Query Neighborhood Hits	47	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BVX2, Q3B761	Gene names	TMEM106C, EMOC
Domain Architecture	No domain graphic available
Description	Transmembrane protein 106C (Endoplasmic reticulum membrane protein overexpressed in cancer).

MA1A2_MOUSE
θ value	6.88961 (rank : 36)	NC score	0.008783 (rank : 75)
Query Neighborhood Hits	47	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	P39098, Q5SUY6, Q5SUY7, Q60599, Q9CUY9	Gene names	Man1a2, Man1b
Domain Architecture
Description	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB (EC 3.2.1.113) (Processing alpha-1,2-mannosidase IB) (Alpha-1,2-mannosidase IB) (Mannosidase alpha class 1A member 2).

STAC_HUMAN
θ value	6.88961 (rank : 37)	NC score	0.021131 (rank : 70)
Query Neighborhood Hits	47	Target Neighborhood Hits	276	Shared Neighborhood Hits	17
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

ZN181_HUMAN
θ value	6.88961 (rank : 38)	NC score	-0.001000 (rank : 83)
Query Neighborhood Hits	47	Target Neighborhood Hits	764	Shared Neighborhood Hits	6
SwissProt Accessions	Q2M3W8, Q49A75	Gene names	ZNF181
Domain Architecture	No domain graphic available
Description	Zinc finger protein 181 (HHZ181).

ZN445_MOUSE
θ value	6.88961 (rank : 39)	NC score	-0.000511 (rank : 81)
Query Neighborhood Hits	47	Target Neighborhood Hits	760	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R2V3, Q8K216	Gene names	Znf445, Zfp445
Domain Architecture
Description	Zinc finger protein 445.

ARHG4_HUMAN
θ value	8.99809 (rank : 40)	NC score	0.019053 (rank : 71)
Query Neighborhood Hits	47	Target Neighborhood Hits	242	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

CELR3_MOUSE
θ value	8.99809 (rank : 41)	NC score	-0.000324 (rank : 80)
Query Neighborhood Hits	47	Target Neighborhood Hits	687	Shared Neighborhood Hits	4
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

GRAP2_HUMAN
θ value	8.99809 (rank : 42)	NC score	0.022409 (rank : 68)
Query Neighborhood Hits	47	Target Neighborhood Hits	304	Shared Neighborhood Hits	22
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

LRP8_HUMAN
θ value	8.99809 (rank : 43)	NC score	0.001255 (rank : 79)
Query Neighborhood Hits	47	Target Neighborhood Hits	346	Shared Neighborhood Hits	4
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

NAL14_HUMAN
θ value	8.99809 (rank : 44)	NC score	0.006215 (rank : 78)
Query Neighborhood Hits	47	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q86W24, Q7RTR6	Gene names	NALP14, NOD5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 14 (Nucleotide-binding oligomerization domain protein 5).

REST_HUMAN
θ value	8.99809 (rank : 45)	NC score	-0.000693 (rank : 82)
Query Neighborhood Hits	47	Target Neighborhood Hits	1605	Shared Neighborhood Hits	5
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

ZN417_HUMAN
θ value	8.99809 (rank : 46)	NC score	-0.001099 (rank : 84)
Query Neighborhood Hits	47	Target Neighborhood Hits	753	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TAU3	Gene names	ZNF417
Domain Architecture	No domain graphic available
Description	Zinc finger protein 417.

ZN587_HUMAN
θ value	8.99809 (rank : 47)	NC score	-0.001109 (rank : 85)
Query Neighborhood Hits	47	Target Neighborhood Hits	756	Shared Neighborhood Hits	6
SwissProt Accessions	Q96SQ5, Q6ZMK8	Gene names	ZNF587
Domain Architecture	No domain graphic available
Description	Zinc finger protein 587.

DLG5_HUMAN
θ value	θ > 10 (rank : 48)	NC score	0.066582 (rank : 41)
Query Neighborhood Hits	47	Target Neighborhood Hits	1088	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

GRIP1_HUMAN
θ value	θ > 10 (rank : 49)	NC score	0.056801 (rank : 50)
Query Neighborhood Hits	47	Target Neighborhood Hits	231	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

GRIP1_MOUSE
θ value	θ > 10 (rank : 50)	NC score	0.056296 (rank : 52)
Query Neighborhood Hits	47	Target Neighborhood Hits	241	Shared Neighborhood Hits	18
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

GRIP2_HUMAN
θ value	θ > 10 (rank : 51)	NC score	0.055937 (rank : 53)
Query Neighborhood Hits	47	Target Neighborhood Hits	256	Shared Neighborhood Hits	19
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

IL16_HUMAN
θ value	θ > 10 (rank : 52)	NC score	0.053789 (rank : 55)
Query Neighborhood Hits	47	Target Neighborhood Hits	207	Shared Neighborhood Hits	16
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

IL16_MOUSE
θ value	θ > 10 (rank : 53)	NC score	0.051854 (rank : 61)
Query Neighborhood Hits	47	Target Neighborhood Hits	189	Shared Neighborhood Hits	18
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

INADL_HUMAN
θ value	θ > 10 (rank : 54)	NC score	0.056483 (rank : 51)
Query Neighborhood Hits	47	Target Neighborhood Hits	260	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

INADL_MOUSE
θ value	θ > 10 (rank : 55)	NC score	0.057381 (rank : 46)
Query Neighborhood Hits	47	Target Neighborhood Hits	290	Shared Neighborhood Hits	19
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

KGUA_HUMAN
θ value	θ > 10 (rank : 56)	NC score	0.128291 (rank : 26)
Query Neighborhood Hits	47	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q16774	Gene names	GUK1, GMK
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

KGUA_MOUSE
θ value	θ > 10 (rank : 57)	NC score	0.152168 (rank : 24)
Query Neighborhood Hits	47	Target Neighborhood Hits	45	Shared Neighborhood Hits	20
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

LIN7A_HUMAN
θ value	θ > 10 (rank : 58)	NC score	0.057639 (rank : 43)
Query Neighborhood Hits	47	Target Neighborhood Hits	193	Shared Neighborhood Hits	19
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

LIN7A_MOUSE
θ value	θ > 10 (rank : 59)	NC score	0.057609 (rank : 44)
Query Neighborhood Hits	47	Target Neighborhood Hits	193	Shared Neighborhood Hits	19
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

LIN7B_HUMAN
θ value	θ > 10 (rank : 60)	NC score	0.057397 (rank : 45)
Query Neighborhood Hits	47	Target Neighborhood Hits	200	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

LIN7B_MOUSE
θ value	θ > 10 (rank : 61)	NC score	0.057326 (rank : 47)
Query Neighborhood Hits	47	Target Neighborhood Hits	200	Shared Neighborhood Hits	19
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

LIN7C_HUMAN
θ value	θ > 10 (rank : 62)	NC score	0.056995 (rank : 48)
Query Neighborhood Hits	47	Target Neighborhood Hits	198	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
θ value	θ > 10 (rank : 63)	NC score	0.056995 (rank : 49)
Query Neighborhood Hits	47	Target Neighborhood Hits	198	Shared Neighborhood Hits	19
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LNX1_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.052507 (rank : 60)
Query Neighborhood Hits	47	Target Neighborhood Hits	379	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX2_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.050095 (rank : 66)
Query Neighborhood Hits	47	Target Neighborhood Hits	389	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

LNX2_MOUSE
θ value	θ > 10 (rank : 66)	NC score	0.051271 (rank : 64)
Query Neighborhood Hits	47	Target Neighborhood Hits	407	Shared Neighborhood Hits	18
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

MPDZ_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.054387 (rank : 54)
Query Neighborhood Hits	47	Target Neighborhood Hits	261	Shared Neighborhood Hits	19
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

MPDZ_MOUSE
θ value	θ > 10 (rank : 68)	NC score	0.052781 (rank : 58)
Query Neighborhood Hits	47	Target Neighborhood Hits	298	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

MPP3_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.128268 (rank : 27)
Query Neighborhood Hits	47	Target Neighborhood Hits	171	Shared Neighborhood Hits	22
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

MPP3_MOUSE
θ value	θ > 10 (rank : 70)	NC score	0.119821 (rank : 29)
Query Neighborhood Hits	47	Target Neighborhood Hits	165	Shared Neighborhood Hits	20
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

MPP4_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.121560 (rank : 28)
Query Neighborhood Hits	47	Target Neighborhood Hits	205	Shared Neighborhood Hits	28
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

MPP4_MOUSE
θ value	θ > 10 (rank : 72)	NC score	0.111533 (rank : 30)
Query Neighborhood Hits	47	Target Neighborhood Hits	188	Shared Neighborhood Hits	23
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

PAR3L_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.053740 (rank : 56)
Query Neighborhood Hits	47	Target Neighborhood Hits	297	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

PARD3_HUMAN
θ value	θ > 10 (rank : 74)	NC score	0.050407 (rank : 65)
Query Neighborhood Hits	47	Target Neighborhood Hits	312	Shared Neighborhood Hits	19
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

PARD3_MOUSE
θ value	θ > 10 (rank : 75)	NC score	0.052661 (rank : 59)
Query Neighborhood Hits	47	Target Neighborhood Hits	290	Shared Neighborhood Hits	17
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

PDZD1_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.053346 (rank : 57)
Query Neighborhood Hits	47	Target Neighborhood Hits	190	Shared Neighborhood Hits	10
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

SYJ2B_HUMAN
θ value	θ > 10 (rank : 77)	NC score	0.066808 (rank : 40)
Query Neighborhood Hits	47	Target Neighborhood Hits	162	Shared Neighborhood Hits	10
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

TX1B3_HUMAN
θ value	θ > 10 (rank : 78)	NC score	0.051381 (rank : 63)
Query Neighborhood Hits	47	Target Neighborhood Hits	161	Shared Neighborhood Hits	10
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

TX1B3_MOUSE
θ value	θ > 10 (rank : 79)	NC score	0.051494 (rank : 62)
Query Neighborhood Hits	47	Target Neighborhood Hits	158	Shared Neighborhood Hits	10
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

ZO1_HUMAN
θ value	θ > 10 (rank : 80)	NC score	0.067973 (rank : 38)
Query Neighborhood Hits	47	Target Neighborhood Hits	474	Shared Neighborhood Hits	19
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO1_MOUSE
θ value	θ > 10 (rank : 81)	NC score	0.067614 (rank : 39)
Query Neighborhood Hits	47	Target Neighborhood Hits	453	Shared Neighborhood Hits	20
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO2_HUMAN
θ value	θ > 10 (rank : 82)	NC score	0.073499 (rank : 35)
Query Neighborhood Hits	47	Target Neighborhood Hits	289	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ZO2_MOUSE
θ value	θ > 10 (rank : 83)	NC score	0.074288 (rank : 34)
Query Neighborhood Hits	47	Target Neighborhood Hits	296	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ZO3_HUMAN
θ value	θ > 10 (rank : 84)	NC score	0.076203 (rank : 33)
Query Neighborhood Hits	47	Target Neighborhood Hits	219	Shared Neighborhood Hits	18
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

ZO3_MOUSE
θ value	θ > 10 (rank : 85)	NC score	0.078539 (rank : 32)
Query Neighborhood Hits	47	Target Neighborhood Hits	224	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

Hits sorted by NC score

CACB4_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	47	Target Neighborhood Hits	47	Shared Neighborhood Hits	47
SwissProt Accessions	O00305, O60515, Q96L40	Gene names	CACNB4, CACNLB4
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-4 (CAB4) (Calcium channel voltage-dependent subunit beta 4).

CACB4_MOUSE
NC score	0.999588 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	47	Target Neighborhood Hits	42	Shared Neighborhood Hits	42
SwissProt Accessions	Q8R0S4, Q8BRN6, Q8CAJ9	Gene names	Cacnb4, Cacnlb4
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-4 (CAB4) (Calcium channel voltage-dependent subunit beta 4).

CACB3_MOUSE
NC score	0.991162 (rank : 3)	θ value	6.35588e-163 (rank : 8)
Query Neighborhood Hits	47	Target Neighborhood Hits	48	Shared Neighborhood Hits	27
SwissProt Accessions	P54285	Gene names	Cacnb3, Cacnlb3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-3 (CAB3) (Calcium channel voltage-dependent subunit beta 3) (CCHB3).

CACB3_HUMAN
NC score	0.991007 (rank : 4)	θ value	3.37019e-164 (rank : 7)
Query Neighborhood Hits	47	Target Neighborhood Hits	45	Shared Neighborhood Hits	26
SwissProt Accessions	P54284, Q13913	Gene names	CACNB3, CACNLB3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-3 (CAB3) (Calcium channel voltage-dependent subunit beta 3).

CACB1_HUMAN
NC score	0.990866 (rank : 5)	θ value	6.34118e-171 (rank : 4)
Query Neighborhood Hits	47	Target Neighborhood Hits	44	Shared Neighborhood Hits	29
SwissProt Accessions	Q02641, O15331, Q02639, Q02640, Q9C085	Gene names	CACNB1, CACNLB1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-1 (CAB1) (Calcium channel voltage-dependent subunit beta 1).

CACB1_MOUSE
NC score	0.990393 (rank : 6)	θ value	4.85525e-171 (rank : 3)
Query Neighborhood Hits	47	Target Neighborhood Hits	46	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R3Z5, O88517, Q7TPF2, Q8R3Z6, Q9EPT9	Gene names	Cacnb1, Cacnlb1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-1 (CAB1) (Calcium channel voltage-dependent subunit beta 1).

CACB2_MOUSE
NC score	0.982113 (rank : 7)	θ value	8.02161e-166 (rank : 6)
Query Neighborhood Hits	47	Target Neighborhood Hits	94	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CC27, Q8C5J5, Q9CTQ6	Gene names	Cacnb2, Cacnlb2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2).

CACB2_HUMAN
NC score	0.980436 (rank : 8)	θ value	3.25673e-167 (rank : 5)
Query Neighborhood Hits	47	Target Neighborhood Hits	99	Shared Neighborhood Hits	28
SwissProt Accessions	Q08289, O00304, Q8WX81, Q96NZ3, Q96NZ4, Q96NZ5, Q9BWU2, Q9HD32, Q9Y340, Q9Y341	Gene names	CACNB2, CACNLB2, MYSB
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2) (Lambert-Eaton myasthenic syndrome antigen B) (MYSB).

DLG3_HUMAN
NC score	0.229188 (rank : 9)	θ value	5.81887e-07 (rank : 9)
Query Neighborhood Hits	47	Target Neighborhood Hits	269	Shared Neighborhood Hits	32
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

DLG1_HUMAN
NC score	0.222827 (rank : 10)	θ value	8.40245e-06 (rank : 11)
Query Neighborhood Hits	47	Target Neighborhood Hits	290	Shared Neighborhood Hits	32
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

DLG1_MOUSE
NC score	0.222089 (rank : 11)	θ value	1.09739e-05 (rank : 12)
Query Neighborhood Hits	47	Target Neighborhood Hits	285	Shared Neighborhood Hits	32
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

DLG3_MOUSE
NC score	0.221604 (rank : 12)	θ value	4.92598e-06 (rank : 10)
Query Neighborhood Hits	47	Target Neighborhood Hits	274	Shared Neighborhood Hits	32
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

MPP6_MOUSE
NC score	0.210735 (rank : 13)	θ value	0.00509761 (rank : 16)
Query Neighborhood Hits	47	Target Neighborhood Hits	187	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

MPP6_HUMAN
NC score	0.207132 (rank : 14)	θ value	0.0148317 (rank : 18)
Query Neighborhood Hits	47	Target Neighborhood Hits	180	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

DLG4_MOUSE
NC score	0.199026 (rank : 15)	θ value	0.000158464 (rank : 13)
Query Neighborhood Hits	47	Target Neighborhood Hits	282	Shared Neighborhood Hits	33
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_HUMAN
NC score	0.198609 (rank : 16)	θ value	0.00020696 (rank : 14)
Query Neighborhood Hits	47	Target Neighborhood Hits	286	Shared Neighborhood Hits	33
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG2_MOUSE
NC score	0.195875 (rank : 17)	θ value	0.00298849 (rank : 15)
Query Neighborhood Hits	47	Target Neighborhood Hits	271	Shared Neighborhood Hits	32
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

MPP5_HUMAN
NC score	0.193218 (rank : 18)	θ value	0.0563607 (rank : 20)
Query Neighborhood Hits	47	Target Neighborhood Hits	231	Shared Neighborhood Hits	31
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPP5_MOUSE
NC score	0.191242 (rank : 19)	θ value	0.0736092 (rank : 21)
Query Neighborhood Hits	47	Target Neighborhood Hits	226	Shared Neighborhood Hits	31
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

DLG2_HUMAN
NC score	0.183661 (rank : 20)	θ value	0.0148317 (rank : 17)
Query Neighborhood Hits	47	Target Neighborhood Hits	279	Shared Neighborhood Hits	32
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

EM55_HUMAN
NC score	0.176427 (rank : 21)	θ value	1.06291 (rank : 27)
Query Neighborhood Hits	47	Target Neighborhood Hits	228	Shared Neighborhood Hits	33
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

EM55_MOUSE
NC score	0.174632 (rank : 22)	θ value	0.62314 (rank : 26)
Query Neighborhood Hits	47	Target Neighborhood Hits	221	Shared Neighborhood Hits	31
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

MPP2_HUMAN
NC score	0.154657 (rank : 23)	θ value	0.163984 (rank : 24)
Query Neighborhood Hits	47	Target Neighborhood Hits	173	Shared Neighborhood Hits	26
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

KGUA_MOUSE
NC score	0.152168 (rank : 24)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	47	Target Neighborhood Hits	45	Shared Neighborhood Hits	20
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

MPP2_MOUSE
NC score	0.145623 (rank : 25)	θ value	1.06291 (rank : 28)
Query Neighborhood Hits	47	Target Neighborhood Hits	189	Shared Neighborhood Hits	26
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

KGUA_HUMAN
NC score	0.128291 (rank : 26)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	47	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q16774	Gene names	GUK1, GMK
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

MPP3_HUMAN
NC score	0.128268 (rank : 27)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	47	Target Neighborhood Hits	171	Shared Neighborhood Hits	22
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

MPP4_HUMAN
NC score	0.121560 (rank : 28)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	47	Target Neighborhood Hits	205	Shared Neighborhood Hits	28
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

MPP3_MOUSE
NC score	0.119821 (rank : 29)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	47	Target Neighborhood Hits	165	Shared Neighborhood Hits	20
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

MPP4_MOUSE
NC score	0.111533 (rank : 30)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	47	Target Neighborhood Hits	188	Shared Neighborhood Hits	23
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

NPHP1_MOUSE
NC score	0.097774 (rank : 31)	θ value	1.06291 (rank : 29)
Query Neighborhood Hits	47	Target Neighborhood Hits	267	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

ZO3_MOUSE
NC score	0.078539 (rank : 32)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	47	Target Neighborhood Hits	224	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

ZO3_HUMAN
NC score	0.076203 (rank : 33)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	47	Target Neighborhood Hits	219	Shared Neighborhood Hits	18
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

ZO2_MOUSE
NC score	0.074288 (rank : 34)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	47	Target Neighborhood Hits	296	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ZO2_HUMAN
NC score	0.073499 (rank : 35)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	47	Target Neighborhood Hits	289	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

CSKP_HUMAN
NC score	0.069465 (rank : 36)	θ value	0.125558 (rank : 23)
Query Neighborhood Hits	47	Target Neighborhood Hits	1022	Shared Neighborhood Hits	31
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

CSKP_MOUSE
NC score	0.068442 (rank : 37)	θ value	0.0961366 (rank : 22)
Query Neighborhood Hits	47	Target Neighborhood Hits	1027	Shared Neighborhood Hits	32
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

ZO1_HUMAN
NC score	0.067973 (rank : 38)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	47	Target Neighborhood Hits	474	Shared Neighborhood Hits	19
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO1_MOUSE
NC score	0.067614 (rank : 39)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	47	Target Neighborhood Hits	453	Shared Neighborhood Hits	20
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

SYJ2B_HUMAN
NC score	0.066808 (rank : 40)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	47	Target Neighborhood Hits	162	Shared Neighborhood Hits	10
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

DLG5_HUMAN
NC score	0.066582 (rank : 41)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	47	Target Neighborhood Hits	1088	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

TS101_HUMAN
NC score	0.060324 (rank : 42)	θ value	3.0926 (rank : 31)
Query Neighborhood Hits	47	Target Neighborhood Hits	359	Shared Neighborhood Hits	8
SwissProt Accessions	Q99816, Q9BUM5	Gene names	TSG101
Domain Architecture
Description	Tumor susceptibility gene 101 protein.

LIN7A_HUMAN
NC score	0.057639 (rank : 43)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	47	Target Neighborhood Hits	193	Shared Neighborhood Hits	19
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

LIN7A_MOUSE
NC score	0.057609 (rank : 44)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	47	Target Neighborhood Hits	193	Shared Neighborhood Hits	19
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

LIN7B_HUMAN
NC score	0.057397 (rank : 45)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	47	Target Neighborhood Hits	200	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

INADL_MOUSE
NC score	0.057381 (rank : 46)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	47	Target Neighborhood Hits	290	Shared Neighborhood Hits	19
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

LIN7B_MOUSE
NC score	0.057326 (rank : 47)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	47	Target Neighborhood Hits	200	Shared Neighborhood Hits	19
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

LIN7C_HUMAN
NC score	0.056995 (rank : 48)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	47	Target Neighborhood Hits	198	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
NC score	0.056995 (rank : 49)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	47	Target Neighborhood Hits	198	Shared Neighborhood Hits	19
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

GRIP1_HUMAN
NC score	0.056801 (rank : 50)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	47	Target Neighborhood Hits	231	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

INADL_HUMAN
NC score	0.056483 (rank : 51)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	47	Target Neighborhood Hits	260	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

GRIP1_MOUSE
NC score	0.056296 (rank : 52)	θ value	θ > 10 (rank : 50)
Query Neighborhood Hits	47	Target Neighborhood Hits	241	Shared Neighborhood Hits	18
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

GRIP2_HUMAN
NC score	0.055937 (rank : 53)	θ value	θ > 10 (rank : 51)
Query Neighborhood Hits	47	Target Neighborhood Hits	256	Shared Neighborhood Hits	19
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

MPDZ_HUMAN
NC score	0.054387 (rank : 54)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	47	Target Neighborhood Hits	261	Shared Neighborhood Hits	19
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

IL16_HUMAN
NC score	0.053789 (rank : 55)	θ value	θ > 10 (rank : 52)
Query Neighborhood Hits	47	Target Neighborhood Hits	207	Shared Neighborhood Hits	16
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

PAR3L_HUMAN
NC score	0.053740 (rank : 56)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	47	Target Neighborhood Hits	297	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

PDZD1_HUMAN
NC score	0.053346 (rank : 57)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	47	Target Neighborhood Hits	190	Shared Neighborhood Hits	10
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

MPDZ_MOUSE
NC score	0.052781 (rank : 58)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	47	Target Neighborhood Hits	298	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

PARD3_MOUSE
NC score	0.052661 (rank : 59)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	47	Target Neighborhood Hits	290	Shared Neighborhood Hits	17
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

LNX1_HUMAN
NC score	0.052507 (rank : 60)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	47	Target Neighborhood Hits	379	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

IL16_MOUSE
NC score	0.051854 (rank : 61)	θ value	θ > 10 (rank : 53)
Query Neighborhood Hits	47	Target Neighborhood Hits	189	Shared Neighborhood Hits	18
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

TX1B3_MOUSE
NC score	0.051494 (rank : 62)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	47	Target Neighborhood Hits	158	Shared Neighborhood Hits	10
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

TX1B3_HUMAN
NC score	0.051381 (rank : 63)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	47	Target Neighborhood Hits	161	Shared Neighborhood Hits	10
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

LNX2_MOUSE
NC score	0.051271 (rank : 64)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	47	Target Neighborhood Hits	407	Shared Neighborhood Hits	18
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

PARD3_HUMAN
NC score	0.050407 (rank : 65)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	47	Target Neighborhood Hits	312	Shared Neighborhood Hits	19
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

LNX2_HUMAN
NC score	0.050095 (rank : 66)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	47	Target Neighborhood Hits	389	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

PDZD6_HUMAN
NC score	0.035920 (rank : 67)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	47	Target Neighborhood Hits	81	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ULD6, Q4W5I8, Q86V55	Gene names	PDZD6, KIAA1284, PDZK6
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 6.

GRAP2_HUMAN
NC score	0.022409 (rank : 68)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	47	Target Neighborhood Hits	304	Shared Neighborhood Hits	22
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

LAMA4_HUMAN
NC score	0.021196 (rank : 69)	θ value	0.0330416 (rank : 19)
Query Neighborhood Hits	47	Target Neighborhood Hits	708	Shared Neighborhood Hits	6
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

STAC_HUMAN
NC score	0.021131 (rank : 70)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	47	Target Neighborhood Hits	276	Shared Neighborhood Hits	17
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

ARHG4_HUMAN
NC score	0.019053 (rank : 71)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	47	Target Neighborhood Hits	242	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

T106C_HUMAN
NC score	0.016604 (rank : 72)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	47	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BVX2, Q3B761	Gene names	TMEM106C, EMOC
Domain Architecture	No domain graphic available
Description	Transmembrane protein 106C (Endoplasmic reticulum membrane protein overexpressed in cancer).

MYO1E_HUMAN
NC score	0.013248 (rank : 73)	θ value	1.38821 (rank : 30)
Query Neighborhood Hits	47	Target Neighborhood Hits	293	Shared Neighborhood Hits	19
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

CBX2_HUMAN
NC score	0.009049 (rank : 74)	θ value	4.03905 (rank : 32)
Query Neighborhood Hits	47	Target Neighborhood Hits	264	Shared Neighborhood Hits	2
SwissProt Accessions	Q14781, Q9BTB1	Gene names	CBX2
Domain Architecture	No domain graphic available
Description	Chromobox protein homolog 2.

MA1A2_MOUSE
NC score	0.008783 (rank : 75)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	47	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	P39098, Q5SUY6, Q5SUY7, Q60599, Q9CUY9	Gene names	Man1a2, Man1b
Domain Architecture
Description	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB (EC 3.2.1.113) (Processing alpha-1,2-mannosidase IB) (Alpha-1,2-mannosidase IB) (Mannosidase alpha class 1A member 2).

SRC_HUMAN
NC score	0.007332 (rank : 76)	θ value	0.47712 (rank : 25)
Query Neighborhood Hits	47	Target Neighborhood Hits	1058	Shared Neighborhood Hits	25
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

PTK6_MOUSE
NC score	0.007121 (rank : 77)	θ value	5.27518 (rank : 34)
Query Neighborhood Hits	47	Target Neighborhood Hits	1026	Shared Neighborhood Hits	26
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

NAL14_HUMAN
NC score	0.006215 (rank : 78)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	47	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q86W24, Q7RTR6	Gene names	NALP14, NOD5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 14 (Nucleotide-binding oligomerization domain protein 5).

LRP8_HUMAN
NC score	0.001255 (rank : 79)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	47	Target Neighborhood Hits	346	Shared Neighborhood Hits	4
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

CELR3_MOUSE
NC score	-0.000324 (rank : 80)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	47	Target Neighborhood Hits	687	Shared Neighborhood Hits	4
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

ZN445_MOUSE
NC score	-0.000511 (rank : 81)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	47	Target Neighborhood Hits	760	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R2V3, Q8K216	Gene names	Znf445, Zfp445
Domain Architecture
Description	Zinc finger protein 445.

REST_HUMAN
NC score	-0.000693 (rank : 82)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	47	Target Neighborhood Hits	1605	Shared Neighborhood Hits	5
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

ZN181_HUMAN
NC score	-0.001000 (rank : 83)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	47	Target Neighborhood Hits	764	Shared Neighborhood Hits	6
SwissProt Accessions	Q2M3W8, Q49A75	Gene names	ZNF181
Domain Architecture	No domain graphic available
Description	Zinc finger protein 181 (HHZ181).

ZN417_HUMAN
NC score	-0.001099 (rank : 84)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	47	Target Neighborhood Hits	753	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TAU3	Gene names	ZNF417
Domain Architecture	No domain graphic available
Description	Zinc finger protein 417.

ZN587_HUMAN
NC score	-0.001109 (rank : 85)	θ value	8.99809 (rank : 47)
Query Neighborhood Hits	47	Target Neighborhood Hits	756	Shared Neighborhood Hits	6
SwissProt Accessions	Q96SQ5, Q6ZMK8	Gene names	ZNF587
Domain Architecture	No domain graphic available
Description	Zinc finger protein 587.