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Network neighborhood for query Sequence : HSF1_HUMAN

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HSF1_HUMAN
SwissProt Accessions	Q00613	Gene names	HSF1, HSTF1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HSF1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	163	Target Neighborhood Hits	163	Shared Neighborhood Hits	163
SwissProt Accessions	Q00613	Gene names	HSF1, HSTF1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

HSF1_MOUSE
θ value	0 (rank : 2)	NC score	0.942551 (rank : 2)
Query Neighborhood Hits	163	Target Neighborhood Hits	267	Shared Neighborhood Hits	85
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

HSF2_HUMAN
θ value	2.02684e-76 (rank : 3)	NC score	0.870171 (rank : 6)
Query Neighborhood Hits	163	Target Neighborhood Hits	149	Shared Neighborhood Hits	17
SwissProt Accessions	Q03933, Q9H445	Gene names	HSF2, HSTF2
Domain Architecture
Description	Heat shock factor protein 2 (HSF 2) (Heat shock transcription factor 2) (HSTF 2).

HSF2_MOUSE
θ value	2.24094e-75 (rank : 4)	NC score	0.870883 (rank : 5)
Query Neighborhood Hits	163	Target Neighborhood Hits	153	Shared Neighborhood Hits	18
SwissProt Accessions	P38533, Q64157, Q8VEJ0, Q9Z2L8	Gene names	Hsf2
Domain Architecture
Description	Heat shock factor protein 2 (HSF 2) (Heat shock transcription factor 2) (HSTF 2).

HSF4_MOUSE
θ value	4.67263e-73 (rank : 5)	NC score	0.894422 (rank : 4)
Query Neighborhood Hits	163	Target Neighborhood Hits	57	Shared Neighborhood Hits	9
SwissProt Accessions	Q9R0L1, Q9R0L2	Gene names	Hsf4
Domain Architecture
Description	Heat shock factor protein 4 (HSF 4) (Heat shock transcription factor 4) (HSTF 4) (mHSF4).

HSF4_HUMAN
θ value	1.35953e-72 (rank : 6)	NC score	0.896115 (rank : 3)
Query Neighborhood Hits	163	Target Neighborhood Hits	72	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ULV5, Q99472, Q9ULV6	Gene names	HSF4
Domain Architecture
Description	Heat shock factor protein 4 (HSF 4) (Heat shock transcription factor 4) (HSTF 4) (hHSF4).

HSFY1_HUMAN
θ value	1.53129e-07 (rank : 7)	NC score	0.515615 (rank : 7)
Query Neighborhood Hits	163	Target Neighborhood Hits	12	Shared Neighborhood Hits	7
SwissProt Accessions	Q96LI6, Q7Z4L8, Q9BZA2, Q9BZA3	Gene names	HSFY1, HSF2L, HSFY
Domain Architecture
Description	Heat shock transcription factor, Y-linked (Heat shock transcription factor 2-like protein) (HSF2-like).

NACAM_MOUSE
θ value	0.000270298 (rank : 8)	NC score	0.087029 (rank : 9)
Query Neighborhood Hits	163	Target Neighborhood Hits	1866	Shared Neighborhood Hits	97
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

ZN438_HUMAN
θ value	0.0113563 (rank : 9)	NC score	0.025132 (rank : 93)
Query Neighborhood Hits	163	Target Neighborhood Hits	906	Shared Neighborhood Hits	27
SwissProt Accessions	Q7Z4V0, Q5T426, Q658Q4, Q6ZN65	Gene names	ZNF438
Domain Architecture	No domain graphic available
Description	Zinc finger protein 438.

CJ078_MOUSE
θ value	0.0148317 (rank : 10)	NC score	0.117178 (rank : 8)
Query Neighborhood Hits	163	Target Neighborhood Hits	559	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CEND3_MOUSE
θ value	0.0252991 (rank : 11)	NC score	0.051503 (rank : 29)
Query Neighborhood Hits	163	Target Neighborhood Hits	228	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

RAI1_MOUSE
θ value	0.0431538 (rank : 12)	NC score	0.062102 (rank : 18)
Query Neighborhood Hits	163	Target Neighborhood Hits	344	Shared Neighborhood Hits	29
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

ANK2_HUMAN
θ value	0.0563607 (rank : 13)	NC score	0.035177 (rank : 66)
Query Neighborhood Hits	163	Target Neighborhood Hits	1615	Shared Neighborhood Hits	80
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

IRS2_MOUSE
θ value	0.0563607 (rank : 14)	NC score	0.072868 (rank : 14)
Query Neighborhood Hits	163	Target Neighborhood Hits	248	Shared Neighborhood Hits	26
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

SYNP2_MOUSE
θ value	0.0563607 (rank : 15)	NC score	0.058655 (rank : 21)
Query Neighborhood Hits	163	Target Neighborhood Hits	252	Shared Neighborhood Hits	19
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

KCNH2_HUMAN
θ value	0.0736092 (rank : 16)	NC score	0.035228 (rank : 65)
Query Neighborhood Hits	163	Target Neighborhood Hits	158	Shared Neighborhood Hits	15
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

MLL2_HUMAN
θ value	0.0961366 (rank : 17)	NC score	0.066097 (rank : 16)
Query Neighborhood Hits	163	Target Neighborhood Hits	1788	Shared Neighborhood Hits	81
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

RERE_MOUSE
θ value	0.125558 (rank : 18)	NC score	0.056741 (rank : 24)
Query Neighborhood Hits	163	Target Neighborhood Hits	785	Shared Neighborhood Hits	47
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

TRIPB_HUMAN
θ value	0.125558 (rank : 19)	NC score	0.043758 (rank : 41)
Query Neighborhood Hits	163	Target Neighborhood Hits	1587	Shared Neighborhood Hits	55
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

ZF106_MOUSE
θ value	0.163984 (rank : 20)	NC score	0.032503 (rank : 71)
Query Neighborhood Hits	163	Target Neighborhood Hits	472	Shared Neighborhood Hits	22
SwissProt Accessions	O88466, O55185, O88465, O88467, Q792M1, Q792P4, Q8CDZ8, Q8R3I4, Q9ESU3	Gene names	Zfp106, H3a, Sh3bp3, Sirm, Znf474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) (H3a minor histocompatibility antigen) (Son of insulin receptor mutant).

MY18B_HUMAN
θ value	0.21417 (rank : 21)	NC score	0.045603 (rank : 39)
Query Neighborhood Hits	163	Target Neighborhood Hits	1299	Shared Neighborhood Hits	58
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

SMOO_HUMAN
θ value	0.21417 (rank : 22)	NC score	0.056944 (rank : 23)
Query Neighborhood Hits	163	Target Neighborhood Hits	391	Shared Neighborhood Hits	31
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

MYO5A_MOUSE
θ value	0.279714 (rank : 23)	NC score	0.027840 (rank : 81)
Query Neighborhood Hits	163	Target Neighborhood Hits	1117	Shared Neighborhood Hits	41
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

RTP3_MOUSE
θ value	0.279714 (rank : 24)	NC score	0.059182 (rank : 20)
Query Neighborhood Hits	163	Target Neighborhood Hits	374	Shared Neighborhood Hits	41
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

TIEG3_MOUSE
θ value	0.279714 (rank : 25)	NC score	0.011560 (rank : 135)
Query Neighborhood Hits	163	Target Neighborhood Hits	774	Shared Neighborhood Hits	22
SwissProt Accessions	Q8K1S5, Q8BI37	Gene names	Tieg3, Tieg2b
Domain Architecture
Description	Transforming growth factor-beta-inducible early growth response protein 3 (TGFB-inducible early growth response protein 3) (TIEG-3) (TGFB-inducible early growth response protein 2b).

UACA_HUMAN
θ value	0.279714 (rank : 26)	NC score	0.037047 (rank : 61)
Query Neighborhood Hits	163	Target Neighborhood Hits	1622	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

HCN2_MOUSE
θ value	0.365318 (rank : 27)	NC score	0.035044 (rank : 67)
Query Neighborhood Hits	163	Target Neighborhood Hits	278	Shared Neighborhood Hits	25
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

NFH_MOUSE
θ value	0.365318 (rank : 28)	NC score	0.040379 (rank : 50)
Query Neighborhood Hits	163	Target Neighborhood Hits	2247	Shared Neighborhood Hits	101
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PRDM2_HUMAN
θ value	0.365318 (rank : 29)	NC score	0.025988 (rank : 91)
Query Neighborhood Hits	163	Target Neighborhood Hits	1135	Shared Neighborhood Hits	40
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

BAP29_MOUSE
θ value	0.47712 (rank : 30)	NC score	0.086343 (rank : 10)
Query Neighborhood Hits	163	Target Neighborhood Hits	285	Shared Neighborhood Hits	23
SwissProt Accessions	Q61334	Gene names	Bcap29, Bap29
Domain Architecture
Description	B-cell receptor-associated protein 29 (BCR-associated protein Bap29).

NF2L2_MOUSE
θ value	0.47712 (rank : 31)	NC score	0.039883 (rank : 53)
Query Neighborhood Hits	163	Target Neighborhood Hits	183	Shared Neighborhood Hits	16
SwissProt Accessions	Q60795	Gene names	Nfe2l2, Nrf-2, Nrf2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2).

PCQAP_HUMAN
θ value	0.47712 (rank : 32)	NC score	0.080156 (rank : 11)
Query Neighborhood Hits	163	Target Neighborhood Hits	549	Shared Neighborhood Hits	34
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

SETD2_HUMAN
θ value	0.47712 (rank : 33)	NC score	0.052275 (rank : 27)
Query Neighborhood Hits	163	Target Neighborhood Hits	412	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

BAP31_MOUSE
θ value	0.62314 (rank : 34)	NC score	0.075531 (rank : 12)
Query Neighborhood Hits	163	Target Neighborhood Hits	134	Shared Neighborhood Hits	13
SwissProt Accessions	Q61335, Q9D0E9, Q9D8G7	Gene names	Bcap31, Bap31
Domain Architecture
Description	B-cell receptor-associated protein 31 (BCR-associated protein Bap31) (p28 Bap31).

EEA1_MOUSE
θ value	0.62314 (rank : 35)	NC score	0.035565 (rank : 64)
Query Neighborhood Hits	163	Target Neighborhood Hits	1637	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

KLF13_MOUSE
θ value	0.62314 (rank : 36)	NC score	0.015886 (rank : 122)
Query Neighborhood Hits	163	Target Neighborhood Hits	757	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JJZ6, Q9ESX3, Q9JHF8	Gene names	Klf13, Bteb3, Fklf2
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 13 (Transcription factor BTEB3) (Basic transcription element-binding protein 3) (BTE-binding protein 3) (RANTES factor of late activated T-lymphocytes 1) (RFLAT-1) (Erythroid transcription factor FKLF-2).

OBF1_HUMAN
θ value	0.62314 (rank : 37)	NC score	0.057582 (rank : 22)
Query Neighborhood Hits	163	Target Neighborhood Hits	203	Shared Neighborhood Hits	25
SwissProt Accessions	Q16633, Q14983	Gene names	POU2AF1, OBF1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (OCA-B).

BAP31_HUMAN
θ value	0.813845 (rank : 38)	NC score	0.069980 (rank : 15)
Query Neighborhood Hits	163	Target Neighborhood Hits	257	Shared Neighborhood Hits	21
SwissProt Accessions	P51572, Q13836, Q96CF0	Gene names	BCAP31, BAP31, DXS1357E
Domain Architecture
Description	B-cell receptor-associated protein 31 (BCR-associated protein Bap31) (p28 Bap31) (Protein CDM) (6C6-AG tumor-associated antigen).

CXXC6_HUMAN
θ value	0.813845 (rank : 39)	NC score	0.053763 (rank : 26)
Query Neighborhood Hits	163	Target Neighborhood Hits	180	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NFU7, Q5VUP7, Q7Z6B6, Q8TCR1, Q9C0I7	Gene names	CXXC6, KIAA1676, LCX
Domain Architecture	No domain graphic available
Description	CXXC-type zinc finger protein 6 (Leukemia-associated protein with a CXXC domain).

EEA1_HUMAN
θ value	0.813845 (rank : 40)	NC score	0.030580 (rank : 75)
Query Neighborhood Hits	163	Target Neighborhood Hits	1796	Shared Neighborhood Hits	57
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

ESAM_MOUSE
θ value	0.813845 (rank : 41)	NC score	0.024284 (rank : 96)
Query Neighborhood Hits	163	Target Neighborhood Hits	222	Shared Neighborhood Hits	7
SwissProt Accessions	Q925F2	Gene names	Esam, Esam1
Domain Architecture	No domain graphic available
Description	Endothelial cell-selective adhesion molecule precursor.

JPH2_MOUSE
θ value	0.813845 (rank : 42)	NC score	0.041098 (rank : 49)
Query Neighborhood Hits	163	Target Neighborhood Hits	279	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

LPIN3_MOUSE
θ value	0.813845 (rank : 43)	NC score	0.021171 (rank : 108)
Query Neighborhood Hits	163	Target Neighborhood Hits	52	Shared Neighborhood Hits	5
SwissProt Accessions	Q99PI4, Q3TQ75, Q8C7R9	Gene names	Lpin3
Domain Architecture
Description	Lipin-3.

MKL1_HUMAN
θ value	0.813845 (rank : 44)	NC score	0.046583 (rank : 38)
Query Neighborhood Hits	163	Target Neighborhood Hits	232	Shared Neighborhood Hits	27
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

PRGC2_MOUSE
θ value	0.813845 (rank : 45)	NC score	0.042963 (rank : 43)
Query Neighborhood Hits	163	Target Neighborhood Hits	225	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

RP1L1_HUMAN
θ value	0.813845 (rank : 46)	NC score	0.041773 (rank : 46)
Query Neighborhood Hits	163	Target Neighborhood Hits	1072	Shared Neighborhood Hits	53
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

CEND3_HUMAN
θ value	1.06291 (rank : 47)	NC score	0.040031 (rank : 52)
Query Neighborhood Hits	163	Target Neighborhood Hits	275	Shared Neighborhood Hits	14
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

SNIP_MOUSE
θ value	1.06291 (rank : 48)	NC score	0.034792 (rank : 69)
Query Neighborhood Hits	163	Target Neighborhood Hits	319	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QWI6, O70298	Gene names	P140, Kiaa1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

ZN750_MOUSE
θ value	1.06291 (rank : 49)	NC score	0.042332 (rank : 45)
Query Neighborhood Hits	163	Target Neighborhood Hits	346	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

ARHGB_HUMAN
θ value	1.38821 (rank : 50)	NC score	0.015758 (rank : 123)
Query Neighborhood Hits	163	Target Neighborhood Hits	375	Shared Neighborhood Hits	11
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

COFA1_MOUSE
θ value	1.38821 (rank : 51)	NC score	0.016552 (rank : 119)
Query Neighborhood Hits	163	Target Neighborhood Hits	305	Shared Neighborhood Hits	15
SwissProt Accessions	O35206, Q9EQD9	Gene names	Col15a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV)].

OPTN_HUMAN
θ value	1.38821 (rank : 52)	NC score	0.026870 (rank : 88)
Query Neighborhood Hits	163	Target Neighborhood Hits	827	Shared Neighborhood Hits	30
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

PKN2_MOUSE
θ value	1.38821 (rank : 53)	NC score	0.004566 (rank : 159)
Query Neighborhood Hits	163	Target Neighborhood Hits	899	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BWW9, Q80WS2, Q8BJL7	Gene names	Pkn2, Prkcl2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein kinase C- like 2) (Protein-kinase C-related kinase 2).

RERE_HUMAN
θ value	1.38821 (rank : 54)	NC score	0.048581 (rank : 35)
Query Neighborhood Hits	163	Target Neighborhood Hits	779	Shared Neighborhood Hits	46
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RTN4_HUMAN
θ value	1.38821 (rank : 55)	NC score	0.048502 (rank : 36)
Query Neighborhood Hits	163	Target Neighborhood Hits	357	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

ACK1_HUMAN
θ value	1.81305 (rank : 56)	NC score	0.007773 (rank : 154)
Query Neighborhood Hits	163	Target Neighborhood Hits	1140	Shared Neighborhood Hits	40
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

FYCO1_MOUSE
θ value	1.81305 (rank : 57)	NC score	0.026109 (rank : 90)
Query Neighborhood Hits	163	Target Neighborhood Hits	1059	Shared Neighborhood Hits	37
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

HMMR_HUMAN
θ value	1.81305 (rank : 58)	NC score	0.034942 (rank : 68)
Query Neighborhood Hits	163	Target Neighborhood Hits	1082	Shared Neighborhood Hits	37
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

MYO15_MOUSE
θ value	1.81305 (rank : 59)	NC score	0.020787 (rank : 111)
Query Neighborhood Hits	163	Target Neighborhood Hits	467	Shared Neighborhood Hits	45
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

NIN_HUMAN
θ value	1.81305 (rank : 60)	NC score	0.035887 (rank : 62)
Query Neighborhood Hits	163	Target Neighborhood Hits	1416	Shared Neighborhood Hits	51
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

P53_HUMAN
θ value	1.81305 (rank : 61)	NC score	0.044112 (rank : 40)
Query Neighborhood Hits	163	Target Neighborhood Hits	42	Shared Neighborhood Hits	6
SwissProt Accessions	P04637, Q15086, Q15087, Q15088, Q16535, Q16807, Q16808, Q16809, Q16810, Q16811, Q16848, Q86UG1, Q8J016, Q99659, Q9BTM4, Q9HAQ8, Q9NP68, Q9NPJ2, Q9NZD0, Q9UBI2, Q9UQ61	Gene names	TP53, P53
Domain Architecture
Description	Cellular tumor antigen p53 (Tumor suppressor p53) (Phosphoprotein p53) (Antigen NY-CO-13).

PCQAP_MOUSE
θ value	1.81305 (rank : 62)	NC score	0.072961 (rank : 13)
Query Neighborhood Hits	163	Target Neighborhood Hits	506	Shared Neighborhood Hits	32
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

TNIK_HUMAN
θ value	1.81305 (rank : 63)	NC score	0.008618 (rank : 149)
Query Neighborhood Hits	163	Target Neighborhood Hits	1570	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

UBE4B_HUMAN
θ value	1.81305 (rank : 64)	NC score	0.051882 (rank : 28)
Query Neighborhood Hits	163	Target Neighborhood Hits	158	Shared Neighborhood Hits	17
SwissProt Accessions	O95155, O75169, O95338, Q5SZ12, Q5SZ16, Q96QD4, Q9BYI7	Gene names	UBE4B, HDNB1, KIAA0684, UFD2
Domain Architecture
Description	Ubiquitin conjugation factor E4 B (Ubiquitin fusion degradation protein 2) (Homozygously deleted in neuroblastoma 1).

CKAP4_MOUSE
θ value	2.36792 (rank : 65)	NC score	0.032322 (rank : 72)
Query Neighborhood Hits	163	Target Neighborhood Hits	596	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

CS029_HUMAN
θ value	2.36792 (rank : 66)	NC score	0.026871 (rank : 87)
Query Neighborhood Hits	163	Target Neighborhood Hits	329	Shared Neighborhood Hits	19
SwissProt Accessions	Q8WUQ7, O75229, Q7LE08, Q9BTA6, Q9Y5A4	Gene names	C19orf29
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 (NY-REN-24 antigen).

EVC_HUMAN
θ value	2.36792 (rank : 67)	NC score	0.037550 (rank : 59)
Query Neighborhood Hits	163	Target Neighborhood Hits	129	Shared Neighborhood Hits	11
SwissProt Accessions	P57679	Gene names	EVC
Domain Architecture	No domain graphic available
Description	Ellis-van Creveld syndrome protein (DWF-1).

FA47A_HUMAN
θ value	2.36792 (rank : 68)	NC score	0.041400 (rank : 47)
Query Neighborhood Hits	163	Target Neighborhood Hits	451	Shared Neighborhood Hits	37
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

IRS2_HUMAN
θ value	2.36792 (rank : 69)	NC score	0.050559 (rank : 30)
Query Neighborhood Hits	163	Target Neighborhood Hits	262	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

KIF3C_MOUSE
θ value	2.36792 (rank : 70)	NC score	0.017479 (rank : 116)
Query Neighborhood Hits	163	Target Neighborhood Hits	468	Shared Neighborhood Hits	25
SwissProt Accessions	O35066, O35229	Gene names	Kif3c
Domain Architecture
Description	Kinesin-like protein KIF3C.

MTF1_MOUSE
θ value	2.36792 (rank : 71)	NC score	0.003289 (rank : 164)
Query Neighborhood Hits	163	Target Neighborhood Hits	785	Shared Neighborhood Hits	18
SwissProt Accessions	Q07243	Gene names	Mtf1, Mtf-1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

PCLO_MOUSE
θ value	2.36792 (rank : 72)	NC score	0.039486 (rank : 54)
Query Neighborhood Hits	163	Target Neighborhood Hits	2275	Shared Neighborhood Hits	104
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PKHG4_HUMAN
θ value	2.36792 (rank : 73)	NC score	0.022124 (rank : 106)
Query Neighborhood Hits	163	Target Neighborhood Hits	200	Shared Neighborhood Hits	13
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

RIN3_MOUSE
θ value	2.36792 (rank : 74)	NC score	0.035811 (rank : 63)
Query Neighborhood Hits	163	Target Neighborhood Hits	239	Shared Neighborhood Hits	25
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

T22D2_HUMAN
θ value	2.36792 (rank : 75)	NC score	0.038044 (rank : 58)
Query Neighborhood Hits	163	Target Neighborhood Hits	250	Shared Neighborhood Hits	22
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

APC_HUMAN
θ value	3.0926 (rank : 76)	NC score	0.027730 (rank : 83)
Query Neighborhood Hits	163	Target Neighborhood Hits	603	Shared Neighborhood Hits	31
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

BARH2_HUMAN
θ value	3.0926 (rank : 77)	NC score	0.009386 (rank : 146)
Query Neighborhood Hits	163	Target Neighborhood Hits	419	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NY43, Q7Z4N7	Gene names	BARHL2
Domain Architecture
Description	BarH-like 2 homeobox protein.

BAT2_MOUSE
θ value	3.0926 (rank : 78)	NC score	0.041130 (rank : 48)
Query Neighborhood Hits	163	Target Neighborhood Hits	947	Shared Neighborhood Hits	62
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CAC1A_HUMAN
θ value	3.0926 (rank : 79)	NC score	0.011553 (rank : 136)
Query Neighborhood Hits	163	Target Neighborhood Hits	387	Shared Neighborhood Hits	19
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1G_HUMAN
θ value	3.0926 (rank : 80)	NC score	0.023002 (rank : 102)
Query Neighborhood Hits	163	Target Neighborhood Hits	587	Shared Neighborhood Hits	46
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

CROCC_MOUSE
θ value	3.0926 (rank : 81)	NC score	0.025670 (rank : 92)
Query Neighborhood Hits	163	Target Neighborhood Hits	1460	Shared Neighborhood Hits	46
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

KIF3C_HUMAN
θ value	3.0926 (rank : 82)	NC score	0.016725 (rank : 118)
Query Neighborhood Hits	163	Target Neighborhood Hits	478	Shared Neighborhood Hits	26
SwissProt Accessions	O14782, O43544	Gene names	KIF3C
Domain Architecture
Description	Kinesin-like protein KIF3C.

MCR_HUMAN
θ value	3.0926 (rank : 83)	NC score	0.010133 (rank : 143)
Query Neighborhood Hits	163	Target Neighborhood Hits	149	Shared Neighborhood Hits	9
SwissProt Accessions	P08235, Q96KQ8, Q96KQ9	Gene names	NR3C2, MCR, MLR
Domain Architecture
Description	Mineralocorticoid receptor (MR).

NIBL_HUMAN
θ value	3.0926 (rank : 84)	NC score	0.021688 (rank : 107)
Query Neighborhood Hits	163	Target Neighborhood Hits	61	Shared Neighborhood Hits	7
SwissProt Accessions	Q96TA1, Q9BUS2, Q9NT35	Gene names	C9orf88
Domain Architecture	No domain graphic available
Description	Niban-like protein (Meg-3).

OBSCN_HUMAN
θ value	3.0926 (rank : 85)	NC score	0.008247 (rank : 151)
Query Neighborhood Hits	163	Target Neighborhood Hits	1931	Shared Neighborhood Hits	54
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

PCD16_HUMAN
θ value	3.0926 (rank : 86)	NC score	0.006313 (rank : 156)
Query Neighborhood Hits	163	Target Neighborhood Hits	245	Shared Neighborhood Hits	7
SwissProt Accessions	Q96JQ0, O15098	Gene names	DCHS1, CDH19, FIB1, KIAA1773, PCDH16
Domain Architecture
Description	Protocadherin-16 precursor (Dachsous 1) (Cadherin-19) (Fibroblast cadherin 1).

PRGC2_HUMAN
θ value	3.0926 (rank : 87)	NC score	0.048969 (rank : 32)
Query Neighborhood Hits	163	Target Neighborhood Hits	272	Shared Neighborhood Hits	26
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

SYNJ1_MOUSE
θ value	3.0926 (rank : 88)	NC score	0.030487 (rank : 76)
Query Neighborhood Hits	163	Target Neighborhood Hits	516	Shared Neighborhood Hits	40
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

UB7I1_HUMAN
θ value	3.0926 (rank : 89)	NC score	0.027146 (rank : 86)
Query Neighborhood Hits	163	Target Neighborhood Hits	177	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NWF9, Q6Y691, Q75ML7, Q7Z2H7, Q7Z7C1, Q8NHW7, Q9NYT1	Gene names	UBCE7IP1, ZIN
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) (Triad domain-containing protein 3).

ZMYM3_HUMAN
θ value	3.0926 (rank : 90)	NC score	0.018866 (rank : 114)
Query Neighborhood Hits	163	Target Neighborhood Hits	223	Shared Neighborhood Hits	12
SwissProt Accessions	Q14202, O15089	Gene names	ZMYM3, DXS6673E, KIAA0385, ZNF261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261).

CA049_MOUSE
θ value	4.03905 (rank : 91)	NC score	0.026506 (rank : 89)
Query Neighborhood Hits	163	Target Neighborhood Hits	121	Shared Neighborhood Hits	10
SwissProt Accessions	Q14BK3, Q4KKY9, Q9D9J9	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf49 homolog.

DAB2P_MOUSE
θ value	4.03905 (rank : 92)	NC score	0.014004 (rank : 126)
Query Neighborhood Hits	163	Target Neighborhood Hits	284	Shared Neighborhood Hits	19
SwissProt Accessions	Q3UHC7, Q3TPD5, Q3UH44, Q6JTV1, Q80T97	Gene names	Dab2ip, Kiaa1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein).

KIF3B_MOUSE
θ value	4.03905 (rank : 93)	NC score	0.017969 (rank : 115)
Query Neighborhood Hits	163	Target Neighborhood Hits	533	Shared Neighborhood Hits	25
SwissProt Accessions	Q61771	Gene names	Kif3b
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B).

OGFR_HUMAN
θ value	4.03905 (rank : 94)	NC score	0.042793 (rank : 44)
Query Neighborhood Hits	163	Target Neighborhood Hits	1582	Shared Neighborhood Hits	79
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

RCOR3_HUMAN
θ value	4.03905 (rank : 95)	NC score	0.030632 (rank : 74)
Query Neighborhood Hits	163	Target Neighborhood Hits	161	Shared Neighborhood Hits	17
SwissProt Accessions	Q9P2K3, Q5VT47, Q7L9I5, Q8N5U3, Q9NV83	Gene names	RCOR3, KIAA1343
Domain Architecture	No domain graphic available
Description	REST corepressor 3.

RHG26_HUMAN
θ value	4.03905 (rank : 96)	NC score	0.011470 (rank : 138)
Query Neighborhood Hits	163	Target Neighborhood Hits	281	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

TACC2_MOUSE
θ value	4.03905 (rank : 97)	NC score	0.033928 (rank : 70)
Query Neighborhood Hits	163	Target Neighborhood Hits	774	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

TBX18_HUMAN
θ value	4.03905 (rank : 98)	NC score	0.009327 (rank : 147)
Query Neighborhood Hits	163	Target Neighborhood Hits	148	Shared Neighborhood Hits	8
SwissProt Accessions	O95935, Q7Z6U4, Q9UJI6	Gene names	TBX18
Domain Architecture
Description	T-box transcription factor TBX18 (T-box protein 18).

TEKT2_HUMAN
θ value	4.03905 (rank : 99)	NC score	0.023153 (rank : 100)
Query Neighborhood Hits	163	Target Neighborhood Hits	197	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UIF3, O60638	Gene names	TEKT2
Domain Architecture
Description	Tektin-2 (Testicular tektin) (Tektin-t) (Testicular tektin B1-like protein) (Tektin-B1) (TEKTB1).

TRI66_MOUSE
θ value	4.03905 (rank : 100)	NC score	0.025018 (rank : 94)
Query Neighborhood Hits	163	Target Neighborhood Hits	491	Shared Neighborhood Hits	31
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

WASIP_HUMAN
θ value	4.03905 (rank : 101)	NC score	0.047523 (rank : 37)
Query Neighborhood Hits	163	Target Neighborhood Hits	458	Shared Neighborhood Hits	32
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

ACK1_MOUSE
θ value	5.27518 (rank : 102)	NC score	0.006341 (rank : 155)
Query Neighborhood Hits	163	Target Neighborhood Hits	1080	Shared Neighborhood Hits	36
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

ATS19_HUMAN
θ value	5.27518 (rank : 103)	NC score	0.004573 (rank : 158)
Query Neighborhood Hits	163	Target Neighborhood Hits	203	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

CING_HUMAN
θ value	5.27518 (rank : 104)	NC score	0.023047 (rank : 101)
Query Neighborhood Hits	163	Target Neighborhood Hits	1275	Shared Neighborhood Hits	44
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

DTX2_MOUSE
θ value	5.27518 (rank : 105)	NC score	0.011942 (rank : 133)
Query Neighborhood Hits	163	Target Neighborhood Hits	76	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R3P2, Q9CZV3, Q9ER07, Q9ER08	Gene names	Dtx2
Domain Architecture
Description	Protein deltex-2 (Deltex-2) (Deltex2) (mDTX2).

ENAH_MOUSE
θ value	5.27518 (rank : 106)	NC score	0.048644 (rank : 34)
Query Neighborhood Hits	163	Target Neighborhood Hits	919	Shared Neighborhood Hits	62
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

MAST1_HUMAN
θ value	5.27518 (rank : 107)	NC score	0.007827 (rank : 153)
Query Neighborhood Hits	163	Target Neighborhood Hits	1146	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MTLR_HUMAN
θ value	5.27518 (rank : 108)	NC score	-0.000158 (rank : 166)
Query Neighborhood Hits	163	Target Neighborhood Hits	796	Shared Neighborhood Hits	2
SwissProt Accessions	O43193	Gene names	MLNR, GPR38, MTLR, MTLR1
Domain Architecture
Description	Motilin receptor (G-protein coupled receptor 38).

OBF1_MOUSE
θ value	5.27518 (rank : 109)	NC score	0.043408 (rank : 42)
Query Neighborhood Hits	163	Target Neighborhood Hits	73	Shared Neighborhood Hits	11
SwissProt Accessions	Q64693	Gene names	Pou2af1, Obf-1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (BOB1) (OCA-B).

PELP1_MOUSE
θ value	5.27518 (rank : 110)	NC score	0.029805 (rank : 77)
Query Neighborhood Hits	163	Target Neighborhood Hits	709	Shared Neighborhood Hits	43
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

PKN2_HUMAN
θ value	5.27518 (rank : 111)	NC score	0.003706 (rank : 162)
Query Neighborhood Hits	163	Target Neighborhood Hits	892	Shared Neighborhood Hits	18
SwissProt Accessions	Q16513, Q9H1W4	Gene names	PKN2, PRK2, PRKCL2
Domain Architecture
Description	Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein kinase C- like 2) (Protein-kinase C-related kinase 2).

RBP2_MOUSE
θ value	5.27518 (rank : 112)	NC score	0.012586 (rank : 132)
Query Neighborhood Hits	163	Target Neighborhood Hits	232	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ERU9, Q61992, Q8C9K9	Gene names	Ranbp2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2 (RanBP2).

SALL3_HUMAN
θ value	5.27518 (rank : 113)	NC score	0.008795 (rank : 148)
Query Neighborhood Hits	163	Target Neighborhood Hits	1066	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

TLE1_HUMAN
θ value	5.27518 (rank : 114)	NC score	0.015306 (rank : 124)
Query Neighborhood Hits	163	Target Neighborhood Hits	485	Shared Neighborhood Hits	18
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

UVRAG_HUMAN
θ value	5.27518 (rank : 115)	NC score	0.038969 (rank : 55)
Query Neighborhood Hits	163	Target Neighborhood Hits	150	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P2Y5, O00392	Gene names	UVRAG
Domain Architecture	No domain graphic available
Description	UV radiation resistance-associated gene protein (p63).

WNK1_MOUSE
θ value	5.27518 (rank : 116)	NC score	0.009732 (rank : 144)
Query Neighborhood Hits	163	Target Neighborhood Hits	1179	Shared Neighborhood Hits	38
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

WNK4_HUMAN
θ value	5.27518 (rank : 117)	NC score	0.012624 (rank : 131)
Query Neighborhood Hits	163	Target Neighborhood Hits	1043	Shared Neighborhood Hits	35
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

ZAN_HUMAN
θ value	5.27518 (rank : 118)	NC score	0.031868 (rank : 73)
Query Neighborhood Hits	163	Target Neighborhood Hits	679	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ZIMP7_HUMAN
θ value	5.27518 (rank : 119)	NC score	0.016371 (rank : 121)
Query Neighborhood Hits	163	Target Neighborhood Hits	290	Shared Neighborhood Hits	25
SwissProt Accessions	Q8NF64, O94790, Q659A8, Q6JKL5, Q8WTX8, Q96Q01, Q9BQH7	Gene names	ZIMP7, KIAA1886
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

BRD2_HUMAN
θ value	6.88961 (rank : 120)	NC score	0.014994 (rank : 125)
Query Neighborhood Hits	163	Target Neighborhood Hits	242	Shared Neighborhood Hits	18
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

CENPU_MOUSE
θ value	6.88961 (rank : 121)	NC score	0.018908 (rank : 113)
Query Neighborhood Hits	163	Target Neighborhood Hits	137	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C4M7, Q6UNA2, Q9D9U1	Gene names	Mlf1ip, Cenpu
Domain Architecture	No domain graphic available
Description	Centromere protein U (CENP-U) (MLF1-interacting protein).

CJ118_HUMAN
θ value	6.88961 (rank : 122)	NC score	0.024649 (rank : 95)
Query Neighborhood Hits	163	Target Neighborhood Hits	937	Shared Neighborhood Hits	31
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

CJ118_MOUSE
θ value	6.88961 (rank : 123)	NC score	0.027627 (rank : 84)
Query Neighborhood Hits	163	Target Neighborhood Hits	1132	Shared Neighborhood Hits	37
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

DPOLL_HUMAN
θ value	6.88961 (rank : 124)	NC score	0.010466 (rank : 142)
Query Neighborhood Hits	163	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UGP5, Q5JQP5, Q6NUM2, Q9HA10, Q9HB35	Gene names	POLL
Domain Architecture
Description	DNA polymerase lambda (EC 2.7.7.7) (EC 4.2.99.-) (Pol Lambda) (DNA polymerase kappa) (DNA polymerase beta-2) (Pol beta2).

K1958_MOUSE
θ value	6.88961 (rank : 125)	NC score	0.016371 (rank : 120)
Query Neighborhood Hits	163	Target Neighborhood Hits	47	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C4P0, Q8BN62, Q8K1X8	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1958 homolog.

KTN1_MOUSE
θ value	6.88961 (rank : 126)	NC score	0.027579 (rank : 85)
Query Neighborhood Hits	163	Target Neighborhood Hits	1324	Shared Neighborhood Hits	45
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

MKL1_MOUSE
θ value	6.88961 (rank : 127)	NC score	0.038381 (rank : 57)
Query Neighborhood Hits	163	Target Neighborhood Hits	667	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

MUC2_HUMAN
θ value	6.88961 (rank : 128)	NC score	0.038945 (rank : 56)
Query Neighborhood Hits	163	Target Neighborhood Hits	906	Shared Neighborhood Hits	42
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

PRR6_HUMAN
θ value	6.88961 (rank : 129)	NC score	0.022214 (rank : 105)
Query Neighborhood Hits	163	Target Neighborhood Hits	39	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z7K6, Q3L8N5, Q8NFH6	Gene names	PRR6
Domain Architecture	No domain graphic available
Description	Proline-rich protein 6 (Nuclear protein p30).

SEM6B_HUMAN
θ value	6.88961 (rank : 130)	NC score	0.013694 (rank : 128)
Query Neighborhood Hits	163	Target Neighborhood Hits	187	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H3T3, Q9NRK9	Gene names	SEMA6B, SEMAZ
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin Z) (Sema Z).

SH2D3_HUMAN
θ value	6.88961 (rank : 131)	NC score	0.010959 (rank : 140)
Query Neighborhood Hits	163	Target Neighborhood Hits	188	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N5H7, Q5HYE5, Q6UY42, Q8N6X3, Q9Y2X5	Gene names	SH2D3C, NSP3
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (Novel SH2-containing protein 3).

SRRM2_MOUSE
θ value	6.88961 (rank : 132)	NC score	0.040314 (rank : 51)
Query Neighborhood Hits	163	Target Neighborhood Hits	1470	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TAF4_HUMAN
θ value	6.88961 (rank : 133)	NC score	0.053789 (rank : 25)
Query Neighborhood Hits	163	Target Neighborhood Hits	687	Shared Neighborhood Hits	51
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TLE4_MOUSE
θ value	6.88961 (rank : 134)	NC score	0.023800 (rank : 98)
Query Neighborhood Hits	163	Target Neighborhood Hits	482	Shared Neighborhood Hits	25
SwissProt Accessions	Q62441, Q9JKQ9	Gene names	Tle4, Grg4
Domain Architecture
Description	Transducin-like enhancer protein 4 (Groucho-related protein 4) (Grg- 4).

TRI66_HUMAN
θ value	6.88961 (rank : 135)	NC score	0.028958 (rank : 78)
Query Neighborhood Hits	163	Target Neighborhood Hits	479	Shared Neighborhood Hits	35
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

WHRN_HUMAN
θ value	6.88961 (rank : 136)	NC score	0.010511 (rank : 141)
Query Neighborhood Hits	163	Target Neighborhood Hits	325	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

ZCHC5_HUMAN
θ value	6.88961 (rank : 137)	NC score	0.028875 (rank : 79)
Query Neighborhood Hits	163	Target Neighborhood Hits	75	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N8U3	Gene names	ZCCHC5
Domain Architecture
Description	Zinc finger CCHC domain-containing protein 5.

ATF6B_MOUSE
θ value	8.99809 (rank : 138)	NC score	0.013785 (rank : 127)
Query Neighborhood Hits	163	Target Neighborhood Hits	97	Shared Neighborhood Hits	9
SwissProt Accessions	O35451	Gene names	Crebl1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp).

BRD4_MOUSE
θ value	8.99809 (rank : 139)	NC score	0.022466 (rank : 104)
Query Neighborhood Hits	163	Target Neighborhood Hits	845	Shared Neighborhood Hits	50
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

CAC1H_HUMAN
θ value	8.99809 (rank : 140)	NC score	0.013231 (rank : 129)
Query Neighborhood Hits	163	Target Neighborhood Hits	307	Shared Neighborhood Hits	20
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

CENPE_HUMAN
θ value	8.99809 (rank : 141)	NC score	0.020882 (rank : 110)
Query Neighborhood Hits	163	Target Neighborhood Hits	2060	Shared Neighborhood Hits	54
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CSPG3_HUMAN
θ value	8.99809 (rank : 142)	NC score	0.005009 (rank : 157)
Query Neighborhood Hits	163	Target Neighborhood Hits	676	Shared Neighborhood Hits	19
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CUTL2_HUMAN
θ value	8.99809 (rank : 143)	NC score	0.027829 (rank : 82)
Query Neighborhood Hits	163	Target Neighborhood Hits	906	Shared Neighborhood Hits	47
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

EP400_MOUSE
θ value	8.99809 (rank : 144)	NC score	0.012910 (rank : 130)
Query Neighborhood Hits	163	Target Neighborhood Hits	592	Shared Neighborhood Hits	35
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

HCN2_HUMAN
θ value	8.99809 (rank : 145)	NC score	0.023905 (rank : 97)
Query Neighborhood Hits	163	Target Neighborhood Hits	369	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

HIC1_MOUSE
θ value	8.99809 (rank : 146)	NC score	0.004319 (rank : 160)
Query Neighborhood Hits	163	Target Neighborhood Hits	863	Shared Neighborhood Hits	16
SwissProt Accessions	Q9R1Y5, Q9R1Y6, Q9R2B0	Gene names	Hic1
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1).

MD1L1_HUMAN
θ value	8.99809 (rank : 147)	NC score	0.020582 (rank : 112)
Query Neighborhood Hits	163	Target Neighborhood Hits	893	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

MINT_MOUSE
θ value	8.99809 (rank : 148)	NC score	0.028833 (rank : 80)
Query Neighborhood Hits	163	Target Neighborhood Hits	1514	Shared Neighborhood Hits	70
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MLL3_HUMAN
θ value	8.99809 (rank : 149)	NC score	0.048711 (rank : 33)
Query Neighborhood Hits	163	Target Neighborhood Hits	1644	Shared Neighborhood Hits	76
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MYO5C_HUMAN
θ value	8.99809 (rank : 150)	NC score	0.021045 (rank : 109)
Query Neighborhood Hits	163	Target Neighborhood Hits	1206	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

RANB9_HUMAN
θ value	8.99809 (rank : 151)	NC score	0.022815 (rank : 103)
Query Neighborhood Hits	163	Target Neighborhood Hits	179	Shared Neighborhood Hits	17
SwissProt Accessions	Q96S59, O94764, Q6P3T7, Q7LBR2, Q7Z7F9	Gene names	RANBP9, RANBPM
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (RanBP7) (Ran-binding protein M) (RanBPM) (BPM90) (BPM-L).

RBBP6_MOUSE
θ value	8.99809 (rank : 152)	NC score	0.017213 (rank : 117)
Query Neighborhood Hits	163	Target Neighborhood Hits	1014	Shared Neighborhood Hits	31
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RGS3_MOUSE
θ value	8.99809 (rank : 153)	NC score	0.037512 (rank : 60)
Query Neighborhood Hits	163	Target Neighborhood Hits	1621	Shared Neighborhood Hits	86
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SEN2_MOUSE
θ value	8.99809 (rank : 154)	NC score	0.011623 (rank : 134)
Query Neighborhood Hits	163	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P7W5, Q3UYG6	Gene names	Tsen2, Sen2
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen2 (EC 3.1.27.9) (tRNA-intron endonuclease Sen2).

SIPA1_HUMAN
θ value	8.99809 (rank : 155)	NC score	0.009469 (rank : 145)
Query Neighborhood Hits	163	Target Neighborhood Hits	250	Shared Neighborhood Hits	20
SwissProt Accessions	Q96FS4, O14518, O60484, O60618	Gene names	SIPA1, SPA1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1) (p130 SPA-1).

SPEG_HUMAN
θ value	8.99809 (rank : 156)	NC score	0.011489 (rank : 137)
Query Neighborhood Hits	163	Target Neighborhood Hits	1762	Shared Neighborhood Hits	56
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TBX18_MOUSE
θ value	8.99809 (rank : 157)	NC score	0.007952 (rank : 152)
Query Neighborhood Hits	163	Target Neighborhood Hits	58	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EPZ6	Gene names	Tbx18
Domain Architecture
Description	T-box transcription factor TBX18 (T-box protein 18).

TLE4_HUMAN
θ value	8.99809 (rank : 158)	NC score	0.023702 (rank : 99)
Query Neighborhood Hits	163	Target Neighborhood Hits	477	Shared Neighborhood Hits	25
SwissProt Accessions	Q04727, Q5T1Y2, Q9BZ07, Q9BZ08, Q9BZ09, Q9NSL3, Q9ULF9	Gene names	TLE4, KIAA1261
Domain Architecture
Description	Transducin-like enhancer protein 4.

TTC16_MOUSE
θ value	8.99809 (rank : 159)	NC score	0.011018 (rank : 139)
Query Neighborhood Hits	163	Target Neighborhood Hits	98	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C1F5	Gene names	Ttc16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

ULK1_MOUSE
θ value	8.99809 (rank : 160)	NC score	0.004170 (rank : 161)
Query Neighborhood Hits	163	Target Neighborhood Hits	1214	Shared Neighborhood Hits	40
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

WNK1_HUMAN
θ value	8.99809 (rank : 161)	NC score	0.008384 (rank : 150)
Query Neighborhood Hits	163	Target Neighborhood Hits	1158	Shared Neighborhood Hits	36
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

ZN579_HUMAN
θ value	8.99809 (rank : 162)	NC score	0.000948 (rank : 165)
Query Neighborhood Hits	163	Target Neighborhood Hits	726	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NAF0	Gene names	ZNF579
Domain Architecture	No domain graphic available
Description	Zinc finger protein 579.

ZN580_MOUSE
θ value	8.99809 (rank : 163)	NC score	0.003503 (rank : 163)
Query Neighborhood Hits	163	Target Neighborhood Hits	711	Shared Neighborhood Hits	14
SwissProt Accessions	Q9DB38	Gene names	Znf580, Zfp580
Domain Architecture	No domain graphic available
Description	Zinc finger protein 580.

BAP29_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.063436 (rank : 17)
Query Neighborhood Hits	163	Target Neighborhood Hits	362	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UHQ4, O95003	Gene names	BCAP29, BAP29
Domain Architecture
Description	B-cell receptor-associated protein 29 (BCR-associated protein Bap29).

MUC7_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.060668 (rank : 19)
Query Neighborhood Hits	163	Target Neighborhood Hits	538	Shared Neighborhood Hits	41
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

PTRF_MOUSE
θ value	θ > 10 (rank : 166)	NC score	0.050039 (rank : 31)
Query Neighborhood Hits	163	Target Neighborhood Hits	151	Shared Neighborhood Hits	12
SwissProt Accessions	O54724	Gene names	Ptrf
Domain Architecture	No domain graphic available
Description	Polymerase I and transcript release factor.

Hits sorted by NC score

HSF1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	163	Target Neighborhood Hits	163	Shared Neighborhood Hits	163
SwissProt Accessions	Q00613	Gene names	HSF1, HSTF1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

HSF1_MOUSE
NC score	0.942551 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	163	Target Neighborhood Hits	267	Shared Neighborhood Hits	85
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

HSF4_HUMAN
NC score	0.896115 (rank : 3)	θ value	1.35953e-72 (rank : 6)
Query Neighborhood Hits	163	Target Neighborhood Hits	72	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ULV5, Q99472, Q9ULV6	Gene names	HSF4
Domain Architecture
Description	Heat shock factor protein 4 (HSF 4) (Heat shock transcription factor 4) (HSTF 4) (hHSF4).

HSF4_MOUSE
NC score	0.894422 (rank : 4)	θ value	4.67263e-73 (rank : 5)
Query Neighborhood Hits	163	Target Neighborhood Hits	57	Shared Neighborhood Hits	9
SwissProt Accessions	Q9R0L1, Q9R0L2	Gene names	Hsf4
Domain Architecture
Description	Heat shock factor protein 4 (HSF 4) (Heat shock transcription factor 4) (HSTF 4) (mHSF4).

HSF2_MOUSE
NC score	0.870883 (rank : 5)	θ value	2.24094e-75 (rank : 4)
Query Neighborhood Hits	163	Target Neighborhood Hits	153	Shared Neighborhood Hits	18
SwissProt Accessions	P38533, Q64157, Q8VEJ0, Q9Z2L8	Gene names	Hsf2
Domain Architecture
Description	Heat shock factor protein 2 (HSF 2) (Heat shock transcription factor 2) (HSTF 2).

HSF2_HUMAN
NC score	0.870171 (rank : 6)	θ value	2.02684e-76 (rank : 3)
Query Neighborhood Hits	163	Target Neighborhood Hits	149	Shared Neighborhood Hits	17
SwissProt Accessions	Q03933, Q9H445	Gene names	HSF2, HSTF2
Domain Architecture
Description	Heat shock factor protein 2 (HSF 2) (Heat shock transcription factor 2) (HSTF 2).

HSFY1_HUMAN
NC score	0.515615 (rank : 7)	θ value	1.53129e-07 (rank : 7)
Query Neighborhood Hits	163	Target Neighborhood Hits	12	Shared Neighborhood Hits	7
SwissProt Accessions	Q96LI6, Q7Z4L8, Q9BZA2, Q9BZA3	Gene names	HSFY1, HSF2L, HSFY
Domain Architecture
Description	Heat shock transcription factor, Y-linked (Heat shock transcription factor 2-like protein) (HSF2-like).

CJ078_MOUSE
NC score	0.117178 (rank : 8)	θ value	0.0148317 (rank : 10)
Query Neighborhood Hits	163	Target Neighborhood Hits	559	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

NACAM_MOUSE
NC score	0.087029 (rank : 9)	θ value	0.000270298 (rank : 8)
Query Neighborhood Hits	163	Target Neighborhood Hits	1866	Shared Neighborhood Hits	97
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

BAP29_MOUSE
NC score	0.086343 (rank : 10)	θ value	0.47712 (rank : 30)
Query Neighborhood Hits	163	Target Neighborhood Hits	285	Shared Neighborhood Hits	23
SwissProt Accessions	Q61334	Gene names	Bcap29, Bap29
Domain Architecture
Description	B-cell receptor-associated protein 29 (BCR-associated protein Bap29).

PCQAP_HUMAN
NC score	0.080156 (rank : 11)	θ value	0.47712 (rank : 32)
Query Neighborhood Hits	163	Target Neighborhood Hits	549	Shared Neighborhood Hits	34
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

BAP31_MOUSE
NC score	0.075531 (rank : 12)	θ value	0.62314 (rank : 34)
Query Neighborhood Hits	163	Target Neighborhood Hits	134	Shared Neighborhood Hits	13
SwissProt Accessions	Q61335, Q9D0E9, Q9D8G7	Gene names	Bcap31, Bap31
Domain Architecture
Description	B-cell receptor-associated protein 31 (BCR-associated protein Bap31) (p28 Bap31).

PCQAP_MOUSE
NC score	0.072961 (rank : 13)	θ value	1.81305 (rank : 62)
Query Neighborhood Hits	163	Target Neighborhood Hits	506	Shared Neighborhood Hits	32
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

IRS2_MOUSE
NC score	0.072868 (rank : 14)	θ value	0.0563607 (rank : 14)
Query Neighborhood Hits	163	Target Neighborhood Hits	248	Shared Neighborhood Hits	26
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

BAP31_HUMAN
NC score	0.069980 (rank : 15)	θ value	0.813845 (rank : 38)
Query Neighborhood Hits	163	Target Neighborhood Hits	257	Shared Neighborhood Hits	21
SwissProt Accessions	P51572, Q13836, Q96CF0	Gene names	BCAP31, BAP31, DXS1357E
Domain Architecture
Description	B-cell receptor-associated protein 31 (BCR-associated protein Bap31) (p28 Bap31) (Protein CDM) (6C6-AG tumor-associated antigen).

MLL2_HUMAN
NC score	0.066097 (rank : 16)	θ value	0.0961366 (rank : 17)
Query Neighborhood Hits	163	Target Neighborhood Hits	1788	Shared Neighborhood Hits	81
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

BAP29_HUMAN
NC score	0.063436 (rank : 17)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	163	Target Neighborhood Hits	362	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UHQ4, O95003	Gene names	BCAP29, BAP29
Domain Architecture
Description	B-cell receptor-associated protein 29 (BCR-associated protein Bap29).

RAI1_MOUSE
NC score	0.062102 (rank : 18)	θ value	0.0431538 (rank : 12)
Query Neighborhood Hits	163	Target Neighborhood Hits	344	Shared Neighborhood Hits	29
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

MUC7_HUMAN
NC score	0.060668 (rank : 19)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	163	Target Neighborhood Hits	538	Shared Neighborhood Hits	41
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

RTP3_MOUSE
NC score	0.059182 (rank : 20)	θ value	0.279714 (rank : 24)
Query Neighborhood Hits	163	Target Neighborhood Hits	374	Shared Neighborhood Hits	41
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

SYNP2_MOUSE
NC score	0.058655 (rank : 21)	θ value	0.0563607 (rank : 15)
Query Neighborhood Hits	163	Target Neighborhood Hits	252	Shared Neighborhood Hits	19
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

OBF1_HUMAN
NC score	0.057582 (rank : 22)	θ value	0.62314 (rank : 37)
Query Neighborhood Hits	163	Target Neighborhood Hits	203	Shared Neighborhood Hits	25
SwissProt Accessions	Q16633, Q14983	Gene names	POU2AF1, OBF1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (OCA-B).

SMOO_HUMAN
NC score	0.056944 (rank : 23)	θ value	0.21417 (rank : 22)
Query Neighborhood Hits	163	Target Neighborhood Hits	391	Shared Neighborhood Hits	31
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

RERE_MOUSE
NC score	0.056741 (rank : 24)	θ value	0.125558 (rank : 18)
Query Neighborhood Hits	163	Target Neighborhood Hits	785	Shared Neighborhood Hits	47
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

TAF4_HUMAN
NC score	0.053789 (rank : 25)	θ value	6.88961 (rank : 133)
Query Neighborhood Hits	163	Target Neighborhood Hits	687	Shared Neighborhood Hits	51
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

CXXC6_HUMAN
NC score	0.053763 (rank : 26)	θ value	0.813845 (rank : 39)
Query Neighborhood Hits	163	Target Neighborhood Hits	180	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NFU7, Q5VUP7, Q7Z6B6, Q8TCR1, Q9C0I7	Gene names	CXXC6, KIAA1676, LCX
Domain Architecture	No domain graphic available
Description	CXXC-type zinc finger protein 6 (Leukemia-associated protein with a CXXC domain).

SETD2_HUMAN
NC score	0.052275 (rank : 27)	θ value	0.47712 (rank : 33)
Query Neighborhood Hits	163	Target Neighborhood Hits	412	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

UBE4B_HUMAN
NC score	0.051882 (rank : 28)	θ value	1.81305 (rank : 64)
Query Neighborhood Hits	163	Target Neighborhood Hits	158	Shared Neighborhood Hits	17
SwissProt Accessions	O95155, O75169, O95338, Q5SZ12, Q5SZ16, Q96QD4, Q9BYI7	Gene names	UBE4B, HDNB1, KIAA0684, UFD2
Domain Architecture
Description	Ubiquitin conjugation factor E4 B (Ubiquitin fusion degradation protein 2) (Homozygously deleted in neuroblastoma 1).

CEND3_MOUSE
NC score	0.051503 (rank : 29)	θ value	0.0252991 (rank : 11)
Query Neighborhood Hits	163	Target Neighborhood Hits	228	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

IRS2_HUMAN
NC score	0.050559 (rank : 30)	θ value	2.36792 (rank : 69)
Query Neighborhood Hits	163	Target Neighborhood Hits	262	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

PTRF_MOUSE
NC score	0.050039 (rank : 31)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	163	Target Neighborhood Hits	151	Shared Neighborhood Hits	12
SwissProt Accessions	O54724	Gene names	Ptrf
Domain Architecture	No domain graphic available
Description	Polymerase I and transcript release factor.

PRGC2_HUMAN
NC score	0.048969 (rank : 32)	θ value	3.0926 (rank : 87)
Query Neighborhood Hits	163	Target Neighborhood Hits	272	Shared Neighborhood Hits	26
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

MLL3_HUMAN
NC score	0.048711 (rank : 33)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	163	Target Neighborhood Hits	1644	Shared Neighborhood Hits	76
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

ENAH_MOUSE
NC score	0.048644 (rank : 34)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	163	Target Neighborhood Hits	919	Shared Neighborhood Hits	62
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

RERE_HUMAN
NC score	0.048581 (rank : 35)	θ value	1.38821 (rank : 54)
Query Neighborhood Hits	163	Target Neighborhood Hits	779	Shared Neighborhood Hits	46
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RTN4_HUMAN
NC score	0.048502 (rank : 36)	θ value	1.38821 (rank : 55)
Query Neighborhood Hits	163	Target Neighborhood Hits	357	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

WASIP_HUMAN
NC score	0.047523 (rank : 37)	θ value	4.03905 (rank : 101)
Query Neighborhood Hits	163	Target Neighborhood Hits	458	Shared Neighborhood Hits	32
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

MKL1_HUMAN
NC score	0.046583 (rank : 38)	θ value	0.813845 (rank : 44)
Query Neighborhood Hits	163	Target Neighborhood Hits	232	Shared Neighborhood Hits	27
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

MY18B_HUMAN
NC score	0.045603 (rank : 39)	θ value	0.21417 (rank : 21)
Query Neighborhood Hits	163	Target Neighborhood Hits	1299	Shared Neighborhood Hits	58
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

P53_HUMAN
NC score	0.044112 (rank : 40)	θ value	1.81305 (rank : 61)
Query Neighborhood Hits	163	Target Neighborhood Hits	42	Shared Neighborhood Hits	6
SwissProt Accessions	P04637, Q15086, Q15087, Q15088, Q16535, Q16807, Q16808, Q16809, Q16810, Q16811, Q16848, Q86UG1, Q8J016, Q99659, Q9BTM4, Q9HAQ8, Q9NP68, Q9NPJ2, Q9NZD0, Q9UBI2, Q9UQ61	Gene names	TP53, P53
Domain Architecture
Description	Cellular tumor antigen p53 (Tumor suppressor p53) (Phosphoprotein p53) (Antigen NY-CO-13).

TRIPB_HUMAN
NC score	0.043758 (rank : 41)	θ value	0.125558 (rank : 19)
Query Neighborhood Hits	163	Target Neighborhood Hits	1587	Shared Neighborhood Hits	55
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

OBF1_MOUSE
NC score	0.043408 (rank : 42)	θ value	5.27518 (rank : 109)
Query Neighborhood Hits	163	Target Neighborhood Hits	73	Shared Neighborhood Hits	11
SwissProt Accessions	Q64693	Gene names	Pou2af1, Obf-1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (BOB1) (OCA-B).

PRGC2_MOUSE
NC score	0.042963 (rank : 43)	θ value	0.813845 (rank : 45)
Query Neighborhood Hits	163	Target Neighborhood Hits	225	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

OGFR_HUMAN
NC score	0.042793 (rank : 44)	θ value	4.03905 (rank : 94)
Query Neighborhood Hits	163	Target Neighborhood Hits	1582	Shared Neighborhood Hits	79
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

ZN750_MOUSE
NC score	0.042332 (rank : 45)	θ value	1.06291 (rank : 49)
Query Neighborhood Hits	163	Target Neighborhood Hits	346	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

RP1L1_HUMAN
NC score	0.041773 (rank : 46)	θ value	0.813845 (rank : 46)
Query Neighborhood Hits	163	Target Neighborhood Hits	1072	Shared Neighborhood Hits	53
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

FA47A_HUMAN
NC score	0.041400 (rank : 47)	θ value	2.36792 (rank : 68)
Query Neighborhood Hits	163	Target Neighborhood Hits	451	Shared Neighborhood Hits	37
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

BAT2_MOUSE
NC score	0.041130 (rank : 48)	θ value	3.0926 (rank : 78)
Query Neighborhood Hits	163	Target Neighborhood Hits	947	Shared Neighborhood Hits	62
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

JPH2_MOUSE
NC score	0.041098 (rank : 49)	θ value	0.813845 (rank : 42)
Query Neighborhood Hits	163	Target Neighborhood Hits	279	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

NFH_MOUSE
NC score	0.040379 (rank : 50)	θ value	0.365318 (rank : 28)
Query Neighborhood Hits	163	Target Neighborhood Hits	2247	Shared Neighborhood Hits	101
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SRRM2_MOUSE
NC score	0.040314 (rank : 51)	θ value	6.88961 (rank : 132)
Query Neighborhood Hits	163	Target Neighborhood Hits	1470	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

CEND3_HUMAN
NC score	0.040031 (rank : 52)	θ value	1.06291 (rank : 47)
Query Neighborhood Hits	163	Target Neighborhood Hits	275	Shared Neighborhood Hits	14
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

NF2L2_MOUSE
NC score	0.039883 (rank : 53)	θ value	0.47712 (rank : 31)
Query Neighborhood Hits	163	Target Neighborhood Hits	183	Shared Neighborhood Hits	16
SwissProt Accessions	Q60795	Gene names	Nfe2l2, Nrf-2, Nrf2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2).

PCLO_MOUSE
NC score	0.039486 (rank : 54)	θ value	2.36792 (rank : 72)
Query Neighborhood Hits	163	Target Neighborhood Hits	2275	Shared Neighborhood Hits	104
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

UVRAG_HUMAN
NC score	0.038969 (rank : 55)	θ value	5.27518 (rank : 115)
Query Neighborhood Hits	163	Target Neighborhood Hits	150	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P2Y5, O00392	Gene names	UVRAG
Domain Architecture	No domain graphic available
Description	UV radiation resistance-associated gene protein (p63).

MUC2_HUMAN
NC score	0.038945 (rank : 56)	θ value	6.88961 (rank : 128)
Query Neighborhood Hits	163	Target Neighborhood Hits	906	Shared Neighborhood Hits	42
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MKL1_MOUSE
NC score	0.038381 (rank : 57)	θ value	6.88961 (rank : 127)
Query Neighborhood Hits	163	Target Neighborhood Hits	667	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

T22D2_HUMAN
NC score	0.038044 (rank : 58)	θ value	2.36792 (rank : 75)
Query Neighborhood Hits	163	Target Neighborhood Hits	250	Shared Neighborhood Hits	22
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

EVC_HUMAN
NC score	0.037550 (rank : 59)	θ value	2.36792 (rank : 67)
Query Neighborhood Hits	163	Target Neighborhood Hits	129	Shared Neighborhood Hits	11
SwissProt Accessions	P57679	Gene names	EVC
Domain Architecture	No domain graphic available
Description	Ellis-van Creveld syndrome protein (DWF-1).

RGS3_MOUSE
NC score	0.037512 (rank : 60)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	163	Target Neighborhood Hits	1621	Shared Neighborhood Hits	86
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

UACA_HUMAN
NC score	0.037047 (rank : 61)	θ value	0.279714 (rank : 26)
Query Neighborhood Hits	163	Target Neighborhood Hits	1622	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

NIN_HUMAN
NC score	0.035887 (rank : 62)	θ value	1.81305 (rank : 60)
Query Neighborhood Hits	163	Target Neighborhood Hits	1416	Shared Neighborhood Hits	51
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

RIN3_MOUSE
NC score	0.035811 (rank : 63)	θ value	2.36792 (rank : 74)
Query Neighborhood Hits	163	Target Neighborhood Hits	239	Shared Neighborhood Hits	25
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

EEA1_MOUSE
NC score	0.035565 (rank : 64)	θ value	0.62314 (rank : 35)
Query Neighborhood Hits	163	Target Neighborhood Hits	1637	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

KCNH2_HUMAN
NC score	0.035228 (rank : 65)	θ value	0.0736092 (rank : 16)
Query Neighborhood Hits	163	Target Neighborhood Hits	158	Shared Neighborhood Hits	15
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

ANK2_HUMAN
NC score	0.035177 (rank : 66)	θ value	0.0563607 (rank : 13)
Query Neighborhood Hits	163	Target Neighborhood Hits	1615	Shared Neighborhood Hits	80
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

HCN2_MOUSE
NC score	0.035044 (rank : 67)	θ value	0.365318 (rank : 27)
Query Neighborhood Hits	163	Target Neighborhood Hits	278	Shared Neighborhood Hits	25
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

HMMR_HUMAN
NC score	0.034942 (rank : 68)	θ value	1.81305 (rank : 58)
Query Neighborhood Hits	163	Target Neighborhood Hits	1082	Shared Neighborhood Hits	37
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

SNIP_MOUSE
NC score	0.034792 (rank : 69)	θ value	1.06291 (rank : 48)
Query Neighborhood Hits	163	Target Neighborhood Hits	319	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QWI6, O70298	Gene names	P140, Kiaa1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

TACC2_MOUSE
NC score	0.033928 (rank : 70)	θ value	4.03905 (rank : 97)
Query Neighborhood Hits	163	Target Neighborhood Hits	774	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

ZF106_MOUSE
NC score	0.032503 (rank : 71)	θ value	0.163984 (rank : 20)
Query Neighborhood Hits	163	Target Neighborhood Hits	472	Shared Neighborhood Hits	22
SwissProt Accessions	O88466, O55185, O88465, O88467, Q792M1, Q792P4, Q8CDZ8, Q8R3I4, Q9ESU3	Gene names	Zfp106, H3a, Sh3bp3, Sirm, Znf474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) (H3a minor histocompatibility antigen) (Son of insulin receptor mutant).

CKAP4_MOUSE
NC score	0.032322 (rank : 72)	θ value	2.36792 (rank : 65)
Query Neighborhood Hits	163	Target Neighborhood Hits	596	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

ZAN_HUMAN
NC score	0.031868 (rank : 73)	θ value	5.27518 (rank : 118)
Query Neighborhood Hits	163	Target Neighborhood Hits	679	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

RCOR3_HUMAN
NC score	0.030632 (rank : 74)	θ value	4.03905 (rank : 95)
Query Neighborhood Hits	163	Target Neighborhood Hits	161	Shared Neighborhood Hits	17
SwissProt Accessions	Q9P2K3, Q5VT47, Q7L9I5, Q8N5U3, Q9NV83	Gene names	RCOR3, KIAA1343
Domain Architecture	No domain graphic available
Description	REST corepressor 3.

EEA1_HUMAN
NC score	0.030580 (rank : 75)	θ value	0.813845 (rank : 40)
Query Neighborhood Hits	163	Target Neighborhood Hits	1796	Shared Neighborhood Hits	57
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

SYNJ1_MOUSE
NC score	0.030487 (rank : 76)	θ value	3.0926 (rank : 88)
Query Neighborhood Hits	163	Target Neighborhood Hits	516	Shared Neighborhood Hits	40
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

PELP1_MOUSE
NC score	0.029805 (rank : 77)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	163	Target Neighborhood Hits	709	Shared Neighborhood Hits	43
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

TRI66_HUMAN
NC score	0.028958 (rank : 78)	θ value	6.88961 (rank : 135)
Query Neighborhood Hits	163	Target Neighborhood Hits	479	Shared Neighborhood Hits	35
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

ZCHC5_HUMAN
NC score	0.028875 (rank : 79)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	163	Target Neighborhood Hits	75	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N8U3	Gene names	ZCCHC5
Domain Architecture
Description	Zinc finger CCHC domain-containing protein 5.

MINT_MOUSE
NC score	0.028833 (rank : 80)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	163	Target Neighborhood Hits	1514	Shared Neighborhood Hits	70
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MYO5A_MOUSE
NC score	0.027840 (rank : 81)	θ value	0.279714 (rank : 23)
Query Neighborhood Hits	163	Target Neighborhood Hits	1117	Shared Neighborhood Hits	41
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

CUTL2_HUMAN
NC score	0.027829 (rank : 82)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	163	Target Neighborhood Hits	906	Shared Neighborhood Hits	47
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

APC_HUMAN
NC score	0.027730 (rank : 83)	θ value	3.0926 (rank : 76)
Query Neighborhood Hits	163	Target Neighborhood Hits	603	Shared Neighborhood Hits	31
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

CJ118_MOUSE
NC score	0.027627 (rank : 84)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	163	Target Neighborhood Hits	1132	Shared Neighborhood Hits	37
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

KTN1_MOUSE
NC score	0.027579 (rank : 85)	θ value	6.88961 (rank : 126)
Query Neighborhood Hits	163	Target Neighborhood Hits	1324	Shared Neighborhood Hits	45
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

UB7I1_HUMAN
NC score	0.027146 (rank : 86)	θ value	3.0926 (rank : 89)
Query Neighborhood Hits	163	Target Neighborhood Hits	177	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NWF9, Q6Y691, Q75ML7, Q7Z2H7, Q7Z7C1, Q8NHW7, Q9NYT1	Gene names	UBCE7IP1, ZIN
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) (Triad domain-containing protein 3).

CS029_HUMAN
NC score	0.026871 (rank : 87)	θ value	2.36792 (rank : 66)
Query Neighborhood Hits	163	Target Neighborhood Hits	329	Shared Neighborhood Hits	19
SwissProt Accessions	Q8WUQ7, O75229, Q7LE08, Q9BTA6, Q9Y5A4	Gene names	C19orf29
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 (NY-REN-24 antigen).

OPTN_HUMAN
NC score	0.026870 (rank : 88)	θ value	1.38821 (rank : 52)
Query Neighborhood Hits	163	Target Neighborhood Hits	827	Shared Neighborhood Hits	30
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

CA049_MOUSE
NC score	0.026506 (rank : 89)	θ value	4.03905 (rank : 91)
Query Neighborhood Hits	163	Target Neighborhood Hits	121	Shared Neighborhood Hits	10
SwissProt Accessions	Q14BK3, Q4KKY9, Q9D9J9	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf49 homolog.

FYCO1_MOUSE
NC score	0.026109 (rank : 90)	θ value	1.81305 (rank : 57)
Query Neighborhood Hits	163	Target Neighborhood Hits	1059	Shared Neighborhood Hits	37
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

PRDM2_HUMAN
NC score	0.025988 (rank : 91)	θ value	0.365318 (rank : 29)
Query Neighborhood Hits	163	Target Neighborhood Hits	1135	Shared Neighborhood Hits	40
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

CROCC_MOUSE
NC score	0.025670 (rank : 92)	θ value	3.0926 (rank : 81)
Query Neighborhood Hits	163	Target Neighborhood Hits	1460	Shared Neighborhood Hits	46
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

ZN438_HUMAN
NC score	0.025132 (rank : 93)	θ value	0.0113563 (rank : 9)
Query Neighborhood Hits	163	Target Neighborhood Hits	906	Shared Neighborhood Hits	27
SwissProt Accessions	Q7Z4V0, Q5T426, Q658Q4, Q6ZN65	Gene names	ZNF438
Domain Architecture	No domain graphic available
Description	Zinc finger protein 438.

TRI66_MOUSE
NC score	0.025018 (rank : 94)	θ value	4.03905 (rank : 100)
Query Neighborhood Hits	163	Target Neighborhood Hits	491	Shared Neighborhood Hits	31
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

CJ118_HUMAN
NC score	0.024649 (rank : 95)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	163	Target Neighborhood Hits	937	Shared Neighborhood Hits	31
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

ESAM_MOUSE
NC score	0.024284 (rank : 96)	θ value	0.813845 (rank : 41)
Query Neighborhood Hits	163	Target Neighborhood Hits	222	Shared Neighborhood Hits	7
SwissProt Accessions	Q925F2	Gene names	Esam, Esam1
Domain Architecture	No domain graphic available
Description	Endothelial cell-selective adhesion molecule precursor.

HCN2_HUMAN
NC score	0.023905 (rank : 97)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	163	Target Neighborhood Hits	369	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

TLE4_MOUSE
NC score	0.023800 (rank : 98)	θ value	6.88961 (rank : 134)
Query Neighborhood Hits	163	Target Neighborhood Hits	482	Shared Neighborhood Hits	25
SwissProt Accessions	Q62441, Q9JKQ9	Gene names	Tle4, Grg4
Domain Architecture
Description	Transducin-like enhancer protein 4 (Groucho-related protein 4) (Grg- 4).

TLE4_HUMAN
NC score	0.023702 (rank : 99)	θ value	8.99809 (rank : 158)
Query Neighborhood Hits	163	Target Neighborhood Hits	477	Shared Neighborhood Hits	25
SwissProt Accessions	Q04727, Q5T1Y2, Q9BZ07, Q9BZ08, Q9BZ09, Q9NSL3, Q9ULF9	Gene names	TLE4, KIAA1261
Domain Architecture
Description	Transducin-like enhancer protein 4.

TEKT2_HUMAN
NC score	0.023153 (rank : 100)	θ value	4.03905 (rank : 99)
Query Neighborhood Hits	163	Target Neighborhood Hits	197	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UIF3, O60638	Gene names	TEKT2
Domain Architecture
Description	Tektin-2 (Testicular tektin) (Tektin-t) (Testicular tektin B1-like protein) (Tektin-B1) (TEKTB1).

CING_HUMAN
NC score	0.023047 (rank : 101)	θ value	5.27518 (rank : 104)
Query Neighborhood Hits	163	Target Neighborhood Hits	1275	Shared Neighborhood Hits	44
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

CAC1G_HUMAN
NC score	0.023002 (rank : 102)	θ value	3.0926 (rank : 80)
Query Neighborhood Hits	163	Target Neighborhood Hits	587	Shared Neighborhood Hits	46
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

RANB9_HUMAN
NC score	0.022815 (rank : 103)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	163	Target Neighborhood Hits	179	Shared Neighborhood Hits	17
SwissProt Accessions	Q96S59, O94764, Q6P3T7, Q7LBR2, Q7Z7F9	Gene names	RANBP9, RANBPM
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (RanBP7) (Ran-binding protein M) (RanBPM) (BPM90) (BPM-L).

BRD4_MOUSE
NC score	0.022466 (rank : 104)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	163	Target Neighborhood Hits	845	Shared Neighborhood Hits	50
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

PRR6_HUMAN
NC score	0.022214 (rank : 105)	θ value	6.88961 (rank : 129)
Query Neighborhood Hits	163	Target Neighborhood Hits	39	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z7K6, Q3L8N5, Q8NFH6	Gene names	PRR6
Domain Architecture	No domain graphic available
Description	Proline-rich protein 6 (Nuclear protein p30).

PKHG4_HUMAN
NC score	0.022124 (rank : 106)	θ value	2.36792 (rank : 73)
Query Neighborhood Hits	163	Target Neighborhood Hits	200	Shared Neighborhood Hits	13
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

NIBL_HUMAN
NC score	0.021688 (rank : 107)	θ value	3.0926 (rank : 84)
Query Neighborhood Hits	163	Target Neighborhood Hits	61	Shared Neighborhood Hits	7
SwissProt Accessions	Q96TA1, Q9BUS2, Q9NT35	Gene names	C9orf88
Domain Architecture	No domain graphic available
Description	Niban-like protein (Meg-3).

LPIN3_MOUSE
NC score	0.021171 (rank : 108)	θ value	0.813845 (rank : 43)
Query Neighborhood Hits	163	Target Neighborhood Hits	52	Shared Neighborhood Hits	5
SwissProt Accessions	Q99PI4, Q3TQ75, Q8C7R9	Gene names	Lpin3
Domain Architecture
Description	Lipin-3.

MYO5C_HUMAN
NC score	0.021045 (rank : 109)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	163	Target Neighborhood Hits	1206	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

CENPE_HUMAN
NC score	0.020882 (rank : 110)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	163	Target Neighborhood Hits	2060	Shared Neighborhood Hits	54
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

MYO15_MOUSE
NC score	0.020787 (rank : 111)	θ value	1.81305 (rank : 59)
Query Neighborhood Hits	163	Target Neighborhood Hits	467	Shared Neighborhood Hits	45
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

MD1L1_HUMAN
NC score	0.020582 (rank : 112)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	163	Target Neighborhood Hits	893	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

CENPU_MOUSE
NC score	0.018908 (rank : 113)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	163	Target Neighborhood Hits	137	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C4M7, Q6UNA2, Q9D9U1	Gene names	Mlf1ip, Cenpu
Domain Architecture	No domain graphic available
Description	Centromere protein U (CENP-U) (MLF1-interacting protein).

ZMYM3_HUMAN
NC score	0.018866 (rank : 114)	θ value	3.0926 (rank : 90)
Query Neighborhood Hits	163	Target Neighborhood Hits	223	Shared Neighborhood Hits	12
SwissProt Accessions	Q14202, O15089	Gene names	ZMYM3, DXS6673E, KIAA0385, ZNF261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261).

KIF3B_MOUSE
NC score	0.017969 (rank : 115)	θ value	4.03905 (rank : 93)
Query Neighborhood Hits	163	Target Neighborhood Hits	533	Shared Neighborhood Hits	25
SwissProt Accessions	Q61771	Gene names	Kif3b
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B).

KIF3C_MOUSE
NC score	0.017479 (rank : 116)	θ value	2.36792 (rank : 70)
Query Neighborhood Hits	163	Target Neighborhood Hits	468	Shared Neighborhood Hits	25
SwissProt Accessions	O35066, O35229	Gene names	Kif3c
Domain Architecture
Description	Kinesin-like protein KIF3C.

RBBP6_MOUSE
NC score	0.017213 (rank : 117)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	163	Target Neighborhood Hits	1014	Shared Neighborhood Hits	31
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

KIF3C_HUMAN
NC score	0.016725 (rank : 118)	θ value	3.0926 (rank : 82)
Query Neighborhood Hits	163	Target Neighborhood Hits	478	Shared Neighborhood Hits	26
SwissProt Accessions	O14782, O43544	Gene names	KIF3C
Domain Architecture
Description	Kinesin-like protein KIF3C.

COFA1_MOUSE
NC score	0.016552 (rank : 119)	θ value	1.38821 (rank : 51)
Query Neighborhood Hits	163	Target Neighborhood Hits	305	Shared Neighborhood Hits	15
SwissProt Accessions	O35206, Q9EQD9	Gene names	Col15a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV)].

K1958_MOUSE
NC score	0.016371 (rank : 120)	θ value	6.88961 (rank : 125)
Query Neighborhood Hits	163	Target Neighborhood Hits	47	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C4P0, Q8BN62, Q8K1X8	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1958 homolog.

ZIMP7_HUMAN
NC score	0.016371 (rank : 121)	θ value	5.27518 (rank : 119)
Query Neighborhood Hits	163	Target Neighborhood Hits	290	Shared Neighborhood Hits	25
SwissProt Accessions	Q8NF64, O94790, Q659A8, Q6JKL5, Q8WTX8, Q96Q01, Q9BQH7	Gene names	ZIMP7, KIAA1886
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

KLF13_MOUSE
NC score	0.015886 (rank : 122)	θ value	0.62314 (rank : 36)
Query Neighborhood Hits	163	Target Neighborhood Hits	757	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JJZ6, Q9ESX3, Q9JHF8	Gene names	Klf13, Bteb3, Fklf2
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 13 (Transcription factor BTEB3) (Basic transcription element-binding protein 3) (BTE-binding protein 3) (RANTES factor of late activated T-lymphocytes 1) (RFLAT-1) (Erythroid transcription factor FKLF-2).

ARHGB_HUMAN
NC score	0.015758 (rank : 123)	θ value	1.38821 (rank : 50)
Query Neighborhood Hits	163	Target Neighborhood Hits	375	Shared Neighborhood Hits	11
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

TLE1_HUMAN
NC score	0.015306 (rank : 124)	θ value	5.27518 (rank : 114)
Query Neighborhood Hits	163	Target Neighborhood Hits	485	Shared Neighborhood Hits	18
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

BRD2_HUMAN
NC score	0.014994 (rank : 125)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	163	Target Neighborhood Hits	242	Shared Neighborhood Hits	18
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

DAB2P_MOUSE
NC score	0.014004 (rank : 126)	θ value	4.03905 (rank : 92)
Query Neighborhood Hits	163	Target Neighborhood Hits	284	Shared Neighborhood Hits	19
SwissProt Accessions	Q3UHC7, Q3TPD5, Q3UH44, Q6JTV1, Q80T97	Gene names	Dab2ip, Kiaa1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein).

ATF6B_MOUSE
NC score	0.013785 (rank : 127)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	163	Target Neighborhood Hits	97	Shared Neighborhood Hits	9
SwissProt Accessions	O35451	Gene names	Crebl1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp).

SEM6B_HUMAN
NC score	0.013694 (rank : 128)	θ value	6.88961 (rank : 130)
Query Neighborhood Hits	163	Target Neighborhood Hits	187	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H3T3, Q9NRK9	Gene names	SEMA6B, SEMAZ
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin Z) (Sema Z).

CAC1H_HUMAN
NC score	0.013231 (rank : 129)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	163	Target Neighborhood Hits	307	Shared Neighborhood Hits	20
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

EP400_MOUSE
NC score	0.012910 (rank : 130)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	163	Target Neighborhood Hits	592	Shared Neighborhood Hits	35
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

WNK4_HUMAN
NC score	0.012624 (rank : 131)	θ value	5.27518 (rank : 117)
Query Neighborhood Hits	163	Target Neighborhood Hits	1043	Shared Neighborhood Hits	35
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

RBP2_MOUSE
NC score	0.012586 (rank : 132)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	163	Target Neighborhood Hits	232	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ERU9, Q61992, Q8C9K9	Gene names	Ranbp2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2 (RanBP2).

DTX2_MOUSE
NC score	0.011942 (rank : 133)	θ value	5.27518 (rank : 105)
Query Neighborhood Hits	163	Target Neighborhood Hits	76	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R3P2, Q9CZV3, Q9ER07, Q9ER08	Gene names	Dtx2
Domain Architecture
Description	Protein deltex-2 (Deltex-2) (Deltex2) (mDTX2).

SEN2_MOUSE
NC score	0.011623 (rank : 134)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	163	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P7W5, Q3UYG6	Gene names	Tsen2, Sen2
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen2 (EC 3.1.27.9) (tRNA-intron endonuclease Sen2).

TIEG3_MOUSE
NC score	0.011560 (rank : 135)	θ value	0.279714 (rank : 25)
Query Neighborhood Hits	163	Target Neighborhood Hits	774	Shared Neighborhood Hits	22
SwissProt Accessions	Q8K1S5, Q8BI37	Gene names	Tieg3, Tieg2b
Domain Architecture
Description	Transforming growth factor-beta-inducible early growth response protein 3 (TGFB-inducible early growth response protein 3) (TIEG-3) (TGFB-inducible early growth response protein 2b).

CAC1A_HUMAN
NC score	0.011553 (rank : 136)	θ value	3.0926 (rank : 79)
Query Neighborhood Hits	163	Target Neighborhood Hits	387	Shared Neighborhood Hits	19
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

SPEG_HUMAN
NC score	0.011489 (rank : 137)	θ value	8.99809 (rank : 156)
Query Neighborhood Hits	163	Target Neighborhood Hits	1762	Shared Neighborhood Hits	56
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

RHG26_HUMAN
NC score	0.011470 (rank : 138)	θ value	4.03905 (rank : 96)
Query Neighborhood Hits	163	Target Neighborhood Hits	281	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

TTC16_MOUSE
NC score	0.011018 (rank : 139)	θ value	8.99809 (rank : 159)
Query Neighborhood Hits	163	Target Neighborhood Hits	98	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C1F5	Gene names	Ttc16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

SH2D3_HUMAN
NC score	0.010959 (rank : 140)	θ value	6.88961 (rank : 131)
Query Neighborhood Hits	163	Target Neighborhood Hits	188	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N5H7, Q5HYE5, Q6UY42, Q8N6X3, Q9Y2X5	Gene names	SH2D3C, NSP3
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (Novel SH2-containing protein 3).

WHRN_HUMAN
NC score	0.010511 (rank : 141)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	163	Target Neighborhood Hits	325	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

DPOLL_HUMAN
NC score	0.010466 (rank : 142)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	163	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UGP5, Q5JQP5, Q6NUM2, Q9HA10, Q9HB35	Gene names	POLL
Domain Architecture
Description	DNA polymerase lambda (EC 2.7.7.7) (EC 4.2.99.-) (Pol Lambda) (DNA polymerase kappa) (DNA polymerase beta-2) (Pol beta2).

MCR_HUMAN
NC score	0.010133 (rank : 143)	θ value	3.0926 (rank : 83)
Query Neighborhood Hits	163	Target Neighborhood Hits	149	Shared Neighborhood Hits	9
SwissProt Accessions	P08235, Q96KQ8, Q96KQ9	Gene names	NR3C2, MCR, MLR
Domain Architecture
Description	Mineralocorticoid receptor (MR).

WNK1_MOUSE
NC score	0.009732 (rank : 144)	θ value	5.27518 (rank : 116)
Query Neighborhood Hits	163	Target Neighborhood Hits	1179	Shared Neighborhood Hits	38
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

SIPA1_HUMAN
NC score	0.009469 (rank : 145)	θ value	8.99809 (rank : 155)
Query Neighborhood Hits	163	Target Neighborhood Hits	250	Shared Neighborhood Hits	20
SwissProt Accessions	Q96FS4, O14518, O60484, O60618	Gene names	SIPA1, SPA1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1) (p130 SPA-1).

BARH2_HUMAN
NC score	0.009386 (rank : 146)	θ value	3.0926 (rank : 77)
Query Neighborhood Hits	163	Target Neighborhood Hits	419	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NY43, Q7Z4N7	Gene names	BARHL2
Domain Architecture
Description	BarH-like 2 homeobox protein.

TBX18_HUMAN
NC score	0.009327 (rank : 147)	θ value	4.03905 (rank : 98)
Query Neighborhood Hits	163	Target Neighborhood Hits	148	Shared Neighborhood Hits	8
SwissProt Accessions	O95935, Q7Z6U4, Q9UJI6	Gene names	TBX18
Domain Architecture
Description	T-box transcription factor TBX18 (T-box protein 18).

SALL3_HUMAN
NC score	0.008795 (rank : 148)	θ value	5.27518 (rank : 113)
Query Neighborhood Hits	163	Target Neighborhood Hits	1066	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

TNIK_HUMAN
NC score	0.008618 (rank : 149)	θ value	1.81305 (rank : 63)
Query Neighborhood Hits	163	Target Neighborhood Hits	1570	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

WNK1_HUMAN
NC score	0.008384 (rank : 150)	θ value	8.99809 (rank : 161)
Query Neighborhood Hits	163	Target Neighborhood Hits	1158	Shared Neighborhood Hits	36
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

OBSCN_HUMAN
NC score	0.008247 (rank : 151)	θ value	3.0926 (rank : 85)
Query Neighborhood Hits	163	Target Neighborhood Hits	1931	Shared Neighborhood Hits	54
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

TBX18_MOUSE
NC score	0.007952 (rank : 152)	θ value	8.99809 (rank : 157)
Query Neighborhood Hits	163	Target Neighborhood Hits	58	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EPZ6	Gene names	Tbx18
Domain Architecture
Description	T-box transcription factor TBX18 (T-box protein 18).

MAST1_HUMAN
NC score	0.007827 (rank : 153)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	163	Target Neighborhood Hits	1146	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

ACK1_HUMAN
NC score	0.007773 (rank : 154)	θ value	1.81305 (rank : 56)
Query Neighborhood Hits	163	Target Neighborhood Hits	1140	Shared Neighborhood Hits	40
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

ACK1_MOUSE
NC score	0.006341 (rank : 155)	θ value	5.27518 (rank : 102)
Query Neighborhood Hits	163	Target Neighborhood Hits	1080	Shared Neighborhood Hits	36
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

PCD16_HUMAN
NC score	0.006313 (rank : 156)	θ value	3.0926 (rank : 86)
Query Neighborhood Hits	163	Target Neighborhood Hits	245	Shared Neighborhood Hits	7
SwissProt Accessions	Q96JQ0, O15098	Gene names	DCHS1, CDH19, FIB1, KIAA1773, PCDH16
Domain Architecture
Description	Protocadherin-16 precursor (Dachsous 1) (Cadherin-19) (Fibroblast cadherin 1).

CSPG3_HUMAN
NC score	0.005009 (rank : 157)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	163	Target Neighborhood Hits	676	Shared Neighborhood Hits	19
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

ATS19_HUMAN
NC score	0.004573 (rank : 158)	θ value	5.27518 (rank : 103)
Query Neighborhood Hits	163	Target Neighborhood Hits	203	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

PKN2_MOUSE
NC score	0.004566 (rank : 159)	θ value	1.38821 (rank : 53)
Query Neighborhood Hits	163	Target Neighborhood Hits	899	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BWW9, Q80WS2, Q8BJL7	Gene names	Pkn2, Prkcl2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein kinase C- like 2) (Protein-kinase C-related kinase 2).

HIC1_MOUSE
NC score	0.004319 (rank : 160)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	163	Target Neighborhood Hits	863	Shared Neighborhood Hits	16
SwissProt Accessions	Q9R1Y5, Q9R1Y6, Q9R2B0	Gene names	Hic1
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1).

ULK1_MOUSE
NC score	0.004170 (rank : 161)	θ value	8.99809 (rank : 160)
Query Neighborhood Hits	163	Target Neighborhood Hits	1214	Shared Neighborhood Hits	40
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

PKN2_HUMAN
NC score	0.003706 (rank : 162)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	163	Target Neighborhood Hits	892	Shared Neighborhood Hits	18
SwissProt Accessions	Q16513, Q9H1W4	Gene names	PKN2, PRK2, PRKCL2
Domain Architecture
Description	Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein kinase C- like 2) (Protein-kinase C-related kinase 2).

ZN580_MOUSE
NC score	0.003503 (rank : 163)	θ value	8.99809 (rank : 163)
Query Neighborhood Hits	163	Target Neighborhood Hits	711	Shared Neighborhood Hits	14
SwissProt Accessions	Q9DB38	Gene names	Znf580, Zfp580
Domain Architecture	No domain graphic available
Description	Zinc finger protein 580.

MTF1_MOUSE
NC score	0.003289 (rank : 164)	θ value	2.36792 (rank : 71)
Query Neighborhood Hits	163	Target Neighborhood Hits	785	Shared Neighborhood Hits	18
SwissProt Accessions	Q07243	Gene names	Mtf1, Mtf-1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

ZN579_HUMAN
NC score	0.000948 (rank : 165)	θ value	8.99809 (rank : 162)
Query Neighborhood Hits	163	Target Neighborhood Hits	726	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NAF0	Gene names	ZNF579
Domain Architecture	No domain graphic available
Description	Zinc finger protein 579.

MTLR_HUMAN
NC score	-0.000158 (rank : 166)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	163	Target Neighborhood Hits	796	Shared Neighborhood Hits	2
SwissProt Accessions	O43193	Gene names	MLNR, GPR38, MTLR, MTLR1
Domain Architecture
Description	Motilin receptor (G-protein coupled receptor 38).