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Network neighborhood for query Sequence : SYTL2_HUMAN

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SYTL2_HUMAN
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SYTL2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	248	Target Neighborhood Hits	248	Shared Neighborhood Hits	248
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

SYTL2_MOUSE
θ value	0 (rank : 2)	NC score	0.976074 (rank : 2)
Query Neighborhood Hits	248	Target Neighborhood Hits	253	Shared Neighborhood Hits	121
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

SYTL1_HUMAN
θ value	4.50487e-84 (rank : 3)	NC score	0.932837 (rank : 3)
Query Neighborhood Hits	248	Target Neighborhood Hits	227	Shared Neighborhood Hits	108
SwissProt Accessions	Q8IYJ3, Q96BB6, Q96GU6, Q96S89, Q96SI0	Gene names	SYTL1, SLP1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1) (SB146).

SYTL1_MOUSE
θ value	3.22841e-82 (rank : 4)	NC score	0.917972 (rank : 6)
Query Neighborhood Hits	248	Target Neighborhood Hits	314	Shared Neighborhood Hits	107
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

SYTL4_MOUSE
θ value	1.11217e-74 (rank : 5)	NC score	0.919358 (rank : 5)
Query Neighborhood Hits	248	Target Neighborhood Hits	137	Shared Neighborhood Hits	97
SwissProt Accessions	Q9R0Q1, Q8R321, Q9R0Q0	Gene names	Sytl4, Slp4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

SYTL4_HUMAN
θ value	5.51964e-74 (rank : 6)	NC score	0.921384 (rank : 4)
Query Neighborhood Hits	248	Target Neighborhood Hits	138	Shared Neighborhood Hits	97
SwissProt Accessions	Q96C24, Q5H9J3, Q5JPG8, Q8N9P4, Q9H4R0, Q9H4R1	Gene names	SYTL4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

SYTL5_HUMAN
θ value	8.24801e-70 (rank : 7)	NC score	0.910097 (rank : 8)
Query Neighborhood Hits	248	Target Neighborhood Hits	237	Shared Neighborhood Hits	114
SwissProt Accessions	Q8TDW5	Gene names	SYTL5, SLP5
Domain Architecture
Description	Synaptotagmin-like protein 5.

SYTL5_MOUSE
θ value	5.7252e-63 (rank : 8)	NC score	0.913361 (rank : 7)
Query Neighborhood Hits	248	Target Neighborhood Hits	154	Shared Neighborhood Hits	100
SwissProt Accessions	Q80T23, Q812E5	Gene names	Sytl5, Slp5
Domain Architecture
Description	Synaptotagmin-like protein 5.

SYTL3_MOUSE
θ value	4.25575e-50 (rank : 9)	NC score	0.901486 (rank : 9)
Query Neighborhood Hits	248	Target Neighborhood Hits	110	Shared Neighborhood Hits	85
SwissProt Accessions	Q99N48, Q8C506, Q99N47, Q99N49, Q99N54, Q99N79	Gene names	Sytl3, Slp3
Domain Architecture
Description	Synaptotagmin-like protein 3 (Exophilin-6).

SYT3_HUMAN
θ value	6.84181e-24 (rank : 10)	NC score	0.798326 (rank : 12)
Query Neighborhood Hits	248	Target Neighborhood Hits	145	Shared Neighborhood Hits	103
SwissProt Accessions	Q9BQG1, Q8N5Z1, Q8N640	Gene names	SYT3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

SYT3_MOUSE
θ value	1.29031e-22 (rank : 11)	NC score	0.798023 (rank : 13)
Query Neighborhood Hits	248	Target Neighborhood Hits	147	Shared Neighborhood Hits	104
SwissProt Accessions	O35681, P97791, Q80WV1	Gene names	Syt3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

SYT6_MOUSE
θ value	2.87452e-22 (rank : 12)	NC score	0.784711 (rank : 22)
Query Neighborhood Hits	248	Target Neighborhood Hits	132	Shared Neighborhood Hits	100
SwissProt Accessions	Q9R0N8	Gene names	Syt6
Domain Architecture
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

SYT6_HUMAN
θ value	8.36355e-22 (rank : 13)	NC score	0.783832 (rank : 25)
Query Neighborhood Hits	248	Target Neighborhood Hits	138	Shared Neighborhood Hits	100
SwissProt Accessions	Q5T7P8	Gene names	SYT6
Domain Architecture	No domain graphic available
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

RP3A_MOUSE
θ value	1.2077e-20 (rank : 14)	NC score	0.773043 (rank : 34)
Query Neighborhood Hits	248	Target Neighborhood Hits	510	Shared Neighborhood Hits	121
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SYT2_MOUSE
θ value	3.51386e-20 (rank : 15)	NC score	0.792501 (rank : 16)
Query Neighborhood Hits	248	Target Neighborhood Hits	143	Shared Neighborhood Hits	103
SwissProt Accessions	P46097, Q8R0E1	Gene names	Syt2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT2_HUMAN
θ value	4.58923e-20 (rank : 16)	NC score	0.792480 (rank : 17)
Query Neighborhood Hits	248	Target Neighborhood Hits	142	Shared Neighborhood Hits	103
SwissProt Accessions	Q8N9I0, Q496K5, Q8NBE5	Gene names	SYT2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

DOC2B_MOUSE
θ value	5.99374e-20 (rank : 17)	NC score	0.799978 (rank : 10)
Query Neighborhood Hits	248	Target Neighborhood Hits	169	Shared Neighborhood Hits	102
SwissProt Accessions	P70169, Q6NXK3	Gene names	Doc2b
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

RP3A_HUMAN
θ value	1.74391e-19 (rank : 18)	NC score	0.778096 (rank : 29)
Query Neighborhood Hits	248	Target Neighborhood Hits	305	Shared Neighborhood Hits	115
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

DOC2B_HUMAN
θ value	5.07402e-19 (rank : 19)	NC score	0.798769 (rank : 11)
Query Neighborhood Hits	248	Target Neighborhood Hits	150	Shared Neighborhood Hits	102
SwissProt Accessions	Q14184	Gene names	DOC2B
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

SYT10_HUMAN
θ value	6.62687e-19 (rank : 20)	NC score	0.779442 (rank : 27)
Query Neighborhood Hits	248	Target Neighborhood Hits	134	Shared Neighborhood Hits	100
SwissProt Accessions	Q6XYQ8	Gene names	SYT10
Domain Architecture	No domain graphic available
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

SYT10_MOUSE
θ value	6.62687e-19 (rank : 21)	NC score	0.776452 (rank : 30)
Query Neighborhood Hits	248	Target Neighborhood Hits	133	Shared Neighborhood Hits	101
SwissProt Accessions	Q9R0N4	Gene names	Syt10
Domain Architecture
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

SYT11_HUMAN
θ value	1.13037e-18 (rank : 22)	NC score	0.779014 (rank : 28)
Query Neighborhood Hits	248	Target Neighborhood Hits	113	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BT88, Q14998, Q68CT5, Q8IXU3, Q96SU2	Gene names	SYT11, KIAA0080
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

SYT11_MOUSE
θ value	1.92812e-18 (rank : 23)	NC score	0.779555 (rank : 26)
Query Neighborhood Hits	248	Target Neighborhood Hits	116	Shared Neighborhood Hits	99
SwissProt Accessions	Q9R0N3	Gene names	Syt11
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

SYT1_HUMAN
θ value	2.7842e-17 (rank : 24)	NC score	0.784027 (rank : 23)
Query Neighborhood Hits	248	Target Neighborhood Hits	150	Shared Neighborhood Hits	103
SwissProt Accessions	P21579	Gene names	SYT1, SYT
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT1_MOUSE
θ value	2.7842e-17 (rank : 25)	NC score	0.784006 (rank : 24)
Query Neighborhood Hits	248	Target Neighborhood Hits	150	Shared Neighborhood Hits	103
SwissProt Accessions	P46096	Gene names	Syt1
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT9_HUMAN
θ value	4.74913e-17 (rank : 26)	NC score	0.776240 (rank : 31)
Query Neighborhood Hits	248	Target Neighborhood Hits	144	Shared Neighborhood Hits	102
SwissProt Accessions	Q86SS6	Gene names	SYT9
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX).

SYT9_MOUSE
θ value	4.74913e-17 (rank : 27)	NC score	0.774482 (rank : 32)
Query Neighborhood Hits	248	Target Neighborhood Hits	148	Shared Neighborhood Hits	102
SwissProt Accessions	Q9R0N9, Q8C280	Gene names	Syt9, Syt5
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX) (Synaptotagmin V).

PCLO_HUMAN
θ value	1.80466e-16 (rank : 28)	NC score	0.519923 (rank : 52)
Query Neighborhood Hits	248	Target Neighborhood Hits	2046	Shared Neighborhood Hits	168
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SYT4_HUMAN
θ value	2.35696e-16 (rank : 29)	NC score	0.774057 (rank : 33)
Query Neighborhood Hits	248	Target Neighborhood Hits	121	Shared Neighborhood Hits	98
SwissProt Accessions	Q9H2B2, Q9P2K4	Gene names	SYT4, KIAA1342
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

SYT4_MOUSE
θ value	5.25075e-16 (rank : 30)	NC score	0.772073 (rank : 35)
Query Neighborhood Hits	248	Target Neighborhood Hits	123	Shared Neighborhood Hits	96
SwissProt Accessions	P40749, Q3UFC1, Q8BGH3, Q8BRL6	Gene names	Syt4, Syt3
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

DOC2A_HUMAN
θ value	6.85773e-16 (rank : 31)	NC score	0.796487 (rank : 15)
Query Neighborhood Hits	248	Target Neighborhood Hits	144	Shared Neighborhood Hits	100
SwissProt Accessions	Q14183, Q6P4G4, Q7Z5G0, Q8IVX0	Gene names	DOC2A
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha) (Doc2).

DOC2A_MOUSE
θ value	1.16975e-15 (rank : 32)	NC score	0.797529 (rank : 14)
Query Neighborhood Hits	248	Target Neighborhood Hits	140	Shared Neighborhood Hits	99
SwissProt Accessions	Q7TNF0	Gene names	Doc2a
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha).

PCLO_MOUSE
θ value	1.52774e-15 (rank : 33)	NC score	0.488871 (rank : 55)
Query Neighborhood Hits	248	Target Neighborhood Hits	2275	Shared Neighborhood Hits	172
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SYT5_HUMAN
θ value	2.60593e-15 (rank : 34)	NC score	0.789423 (rank : 19)
Query Neighborhood Hits	248	Target Neighborhood Hits	138	Shared Neighborhood Hits	103
SwissProt Accessions	O00445, Q86X72	Gene names	SYT5
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV).

SYT5_MOUSE
θ value	4.44505e-15 (rank : 35)	NC score	0.789779 (rank : 18)
Query Neighborhood Hits	248	Target Neighborhood Hits	140	Shared Neighborhood Hits	103
SwissProt Accessions	Q9R0N5	Gene names	Syt5, Syt9
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV) (Synaptotagmin IX).

SYT7_MOUSE
θ value	9.90251e-15 (rank : 36)	NC score	0.786219 (rank : 20)
Query Neighborhood Hits	248	Target Neighborhood Hits	137	Shared Neighborhood Hits	103
SwissProt Accessions	Q9R0N7	Gene names	Syt7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

SYT7_HUMAN
θ value	1.09485e-13 (rank : 37)	NC score	0.785789 (rank : 21)
Query Neighborhood Hits	248	Target Neighborhood Hits	137	Shared Neighborhood Hits	103
SwissProt Accessions	O43581	Gene names	SYT7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

SYT15_HUMAN
θ value	3.89403e-11 (rank : 38)	NC score	0.742690 (rank : 39)
Query Neighborhood Hits	248	Target Neighborhood Hits	112	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BQS2, Q7Z439, Q7Z440	Gene names	SYT15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV) (Chr10Syt).

KPCG_HUMAN
θ value	5.08577e-11 (rank : 39)	NC score	0.210092 (rank : 92)
Query Neighborhood Hits	248	Target Neighborhood Hits	1126	Shared Neighborhood Hits	110
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

KPCA_HUMAN
θ value	6.64225e-11 (rank : 40)	NC score	0.195759 (rank : 98)
Query Neighborhood Hits	248	Target Neighborhood Hits	1070	Shared Neighborhood Hits	109
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KPCG_MOUSE
θ value	6.64225e-11 (rank : 41)	NC score	0.209795 (rank : 93)
Query Neighborhood Hits	248	Target Neighborhood Hits	1123	Shared Neighborhood Hits	109
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

DOC2G_MOUSE
θ value	1.133e-10 (rank : 42)	NC score	0.768432 (rank : 36)
Query Neighborhood Hits	248	Target Neighborhood Hits	125	Shared Neighborhood Hits	96
SwissProt Accessions	Q9ESN1, Q6P8R8	Gene names	Doc2g
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein gamma (Doc2-gamma).

SYT12_MOUSE
θ value	1.133e-10 (rank : 43)	NC score	0.750682 (rank : 37)
Query Neighborhood Hits	248	Target Neighborhood Hits	102	Shared Neighborhood Hits	88
SwissProt Accessions	Q920N7	Gene names	Syt12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

KPCA_MOUSE
θ value	2.52405e-10 (rank : 44)	NC score	0.192677 (rank : 101)
Query Neighborhood Hits	248	Target Neighborhood Hits	1067	Shared Neighborhood Hits	109
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

P3C2A_HUMAN
θ value	2.52405e-10 (rank : 45)	NC score	0.457690 (rank : 58)
Query Neighborhood Hits	248	Target Neighborhood Hits	188	Shared Neighborhood Hits	78
SwissProt Accessions	O00443	Gene names	PIK3C2A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha).

RIMS1_HUMAN
θ value	9.59137e-10 (rank : 46)	NC score	0.566108 (rank : 48)
Query Neighborhood Hits	248	Target Neighborhood Hits	437	Shared Neighborhood Hits	110
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

SYT12_HUMAN
θ value	9.59137e-10 (rank : 47)	NC score	0.746358 (rank : 38)
Query Neighborhood Hits	248	Target Neighborhood Hits	100	Shared Neighborhood Hits	86
SwissProt Accessions	Q8IV01	Gene names	SYT12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

KPCB_HUMAN
θ value	1.25267e-09 (rank : 48)	NC score	0.192530 (rank : 102)
Query Neighborhood Hits	248	Target Neighborhood Hits	1121	Shared Neighborhood Hits	108
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCB_MOUSE
θ value	1.63604e-09 (rank : 49)	NC score	0.194709 (rank : 99)
Query Neighborhood Hits	248	Target Neighborhood Hits	1117	Shared Neighborhood Hits	107
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

RASA3_HUMAN
θ value	1.63604e-09 (rank : 50)	NC score	0.419648 (rank : 66)
Query Neighborhood Hits	248	Target Neighborhood Hits	166	Shared Neighborhood Hits	82
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

P3C2A_MOUSE
θ value	2.13673e-09 (rank : 51)	NC score	0.453863 (rank : 59)
Query Neighborhood Hits	248	Target Neighborhood Hits	181	Shared Neighborhood Hits	76
SwissProt Accessions	Q61194, Q61182	Gene names	Pik3c2a, Cpk
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).

FA62A_HUMAN
θ value	8.11959e-09 (rank : 52)	NC score	0.633257 (rank : 42)
Query Neighborhood Hits	248	Target Neighborhood Hits	168	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

FA62A_MOUSE
θ value	1.80886e-08 (rank : 53)	NC score	0.632950 (rank : 43)
Query Neighborhood Hits	248	Target Neighborhood Hits	155	Shared Neighborhood Hits	99
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

SYT15_MOUSE
θ value	4.0297e-08 (rank : 54)	NC score	0.703355 (rank : 41)
Query Neighborhood Hits	248	Target Neighborhood Hits	100	Shared Neighborhood Hits	86
SwissProt Accessions	Q8C6N3, Q7TN81, Q7TN82, Q8C999	Gene names	Syt15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV).

RIMS2_HUMAN
θ value	5.81887e-07 (rank : 55)	NC score	0.550825 (rank : 50)
Query Neighborhood Hits	248	Target Neighborhood Hits	342	Shared Neighborhood Hits	108
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
θ value	5.81887e-07 (rank : 56)	NC score	0.544893 (rank : 51)
Query Neighborhood Hits	248	Target Neighborhood Hits	376	Shared Neighborhood Hits	110
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

SYT8_MOUSE
θ value	5.81887e-07 (rank : 57)	NC score	0.733168 (rank : 40)
Query Neighborhood Hits	248	Target Neighborhood Hits	94	Shared Neighborhood Hits	83
SwissProt Accessions	Q9R0N6, Q64366, Q8C6E7	Gene names	Syt8
Domain Architecture
Description	Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII).

P3C2B_HUMAN
θ value	1.29631e-06 (rank : 58)	NC score	0.483614 (rank : 56)
Query Neighborhood Hits	248	Target Neighborhood Hits	148	Shared Neighborhood Hits	83
SwissProt Accessions	O00750, O95666, Q5SW99	Gene names	PIK3C2B
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-beta) (PtdIns-3-kinase C2 beta) (PI3K-C2beta) (C2-PI3K).

RIMS4_MOUSE
θ value	1.69304e-06 (rank : 59)	NC score	0.499791 (rank : 53)
Query Neighborhood Hits	248	Target Neighborhood Hits	76	Shared Neighborhood Hits	71
SwissProt Accessions	P60191	Gene names	Rims4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

RIMS4_HUMAN
θ value	2.21117e-06 (rank : 60)	NC score	0.496240 (rank : 54)
Query Neighborhood Hits	248	Target Neighborhood Hits	76	Shared Neighborhood Hits	71
SwissProt Accessions	Q9H426, Q5JWT7	Gene names	RIMS4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

RASA3_MOUSE
θ value	3.77169e-06 (rank : 61)	NC score	0.362847 (rank : 73)
Query Neighborhood Hits	248	Target Neighborhood Hits	144	Shared Neighborhood Hits	74
SwissProt Accessions	Q60790	Gene names	Rasa3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) (GapIII).

RFIP2_HUMAN
θ value	6.43352e-06 (rank : 62)	NC score	0.373430 (rank : 71)
Query Neighborhood Hits	248	Target Neighborhood Hits	97	Shared Neighborhood Hits	75
SwissProt Accessions	Q7L804, Q9Y2F0	Gene names	RAB11FIP2, KIAA0941
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 2 (Rab11-FIP2) (NRip11).

RASA2_HUMAN
θ value	8.40245e-06 (rank : 63)	NC score	0.439479 (rank : 63)
Query Neighborhood Hits	248	Target Neighborhood Hits	157	Shared Neighborhood Hits	85
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

RASL2_HUMAN
θ value	8.40245e-06 (rank : 64)	NC score	0.565232 (rank : 49)
Query Neighborhood Hits	248	Target Neighborhood Hits	161	Shared Neighborhood Hits	96
SwissProt Accessions	O43374, O60286, Q86UW3, Q96QU0	Gene names	RASA4, CAPRI, GAPL, KIAA0538
Domain Architecture
Description	Ras GTPase-activating protein 4 (RasGAP-activating-like protein 2) (Calcium-promoted Ras inactivator).

TITIN_HUMAN
θ value	1.43324e-05 (rank : 65)	NC score	0.027026 (rank : 201)
Query Neighborhood Hits	248	Target Neighborhood Hits	2923	Shared Neighborhood Hits	81
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

NEDD4_HUMAN
θ value	1.87187e-05 (rank : 66)	NC score	0.289886 (rank : 84)
Query Neighborhood Hits	248	Target Neighborhood Hits	214	Shared Neighborhood Hits	95
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

RASA2_MOUSE
θ value	2.44474e-05 (rank : 67)	NC score	0.445354 (rank : 61)
Query Neighborhood Hits	248	Target Neighborhood Hits	159	Shared Neighborhood Hits	85
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

NED4L_HUMAN
θ value	4.1701e-05 (rank : 68)	NC score	0.310546 (rank : 76)
Query Neighborhood Hits	248	Target Neighborhood Hits	238	Shared Neighborhood Hits	97
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NED4L_MOUSE
θ value	4.1701e-05 (rank : 69)	NC score	0.306576 (rank : 77)
Query Neighborhood Hits	248	Target Neighborhood Hits	231	Shared Neighborhood Hits	95
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NEDD4_MOUSE
θ value	7.1131e-05 (rank : 70)	NC score	0.276959 (rank : 87)
Query Neighborhood Hits	248	Target Neighborhood Hits	212	Shared Neighborhood Hits	95
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

DYSF_HUMAN
θ value	0.00020696 (rank : 71)	NC score	0.364827 (rank : 72)
Query Neighborhood Hits	248	Target Neighborhood Hits	170	Shared Neighborhood Hits	100
SwissProt Accessions	O75923, O75696, Q9UEN7	Gene names	DYSF, FER1L1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

P3C2G_HUMAN
θ value	0.000602161 (rank : 72)	NC score	0.180253 (rank : 106)
Query Neighborhood Hits	248	Target Neighborhood Hits	92	Shared Neighborhood Hits	47
SwissProt Accessions	O75747	Gene names	PIK3C2G
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).

RASL1_MOUSE
θ value	0.000786445 (rank : 73)	NC score	0.452713 (rank : 60)
Query Neighborhood Hits	248	Target Neighborhood Hits	148	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Z268	Gene names	Rasal1, Rasal
Domain Architecture
Description	RasGAP-activating-like protein 1.

RASL1_HUMAN
θ value	0.00228821 (rank : 74)	NC score	0.462660 (rank : 57)
Query Neighborhood Hits	248	Target Neighborhood Hits	142	Shared Neighborhood Hits	85
SwissProt Accessions	O95294, Q52M03, Q96CC7	Gene names	RASAL1, RASAL
Domain Architecture
Description	RasGAP-activating-like protein 1.

PA24D_HUMAN
θ value	0.00298849 (rank : 75)	NC score	0.260514 (rank : 88)
Query Neighborhood Hits	248	Target Neighborhood Hits	97	Shared Neighborhood Hits	74
SwissProt Accessions	Q86XP0, Q8N176	Gene names	PLA2G4D
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

K0528_HUMAN
θ value	0.00390308 (rank : 76)	NC score	0.424150 (rank : 64)
Query Neighborhood Hits	248	Target Neighborhood Hits	96	Shared Neighborhood Hits	77
SwissProt Accessions	Q86YS7, O60280, Q7Z619, Q86SU3	Gene names	KIAA0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

K0528_MOUSE
θ value	0.00390308 (rank : 77)	NC score	0.423688 (rank : 65)
Query Neighborhood Hits	248	Target Neighborhood Hits	102	Shared Neighborhood Hits	78
SwissProt Accessions	Q7TPS5, Q3TQY6, Q6A052, Q80VA1, Q8C0U3, Q8CID5, Q9CS85	Gene names	Kiaa0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

DYSF_MOUSE
θ value	0.00509761 (rank : 78)	NC score	0.359101 (rank : 74)
Query Neighborhood Hits	248	Target Neighborhood Hits	162	Shared Neighborhood Hits	98
SwissProt Accessions	Q9ESD7, Q9QXC0	Gene names	Dysf, Fer1l1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

SYT14_MOUSE
θ value	0.00509761 (rank : 79)	NC score	0.581459 (rank : 46)
Query Neighborhood Hits	248	Target Neighborhood Hits	82	Shared Neighborhood Hits	62
SwissProt Accessions	Q7TN84	Gene names	Syt14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

P3C2G_MOUSE
θ value	0.00665767 (rank : 80)	NC score	0.198599 (rank : 97)
Query Neighborhood Hits	248	Target Neighborhood Hits	113	Shared Neighborhood Hits	64
SwissProt Accessions	O70167, O70168	Gene names	Pik3c2g
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).

SYT14_HUMAN
θ value	0.00665767 (rank : 81)	NC score	0.579287 (rank : 47)
Query Neighborhood Hits	248	Target Neighborhood Hits	81	Shared Neighborhood Hits	60
SwissProt Accessions	Q8NB59, Q5THX7, Q707N3, Q707N4, Q707N5, Q707N6, Q707N7	Gene names	SYT14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

MYOF_HUMAN
θ value	0.00869519 (rank : 82)	NC score	0.353068 (rank : 75)
Query Neighborhood Hits	248	Target Neighborhood Hits	147	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NZM1, Q9HBU3, Q9NZM0, Q9ULL3, Q9Y4U4	Gene names	FER1L3, KIAA1207, MYOF
Domain Architecture
Description	Myoferlin (Fer-1-like protein 3).

OTOF_HUMAN
θ value	0.00869519 (rank : 83)	NC score	0.306229 (rank : 78)
Query Neighborhood Hits	248	Target Neighborhood Hits	168	Shared Neighborhood Hits	79
SwissProt Accessions	Q9HC10, Q9HC08, Q9HC09, Q9Y650	Gene names	OTOF, FER1L2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

SLC2B_HUMAN
θ value	0.0113563 (rank : 84)	NC score	0.185244 (rank : 104)
Query Neighborhood Hits	248	Target Neighborhood Hits	214	Shared Neighborhood Hits	34
SwissProt Accessions	Q8NEV8, Q9Y4D6	Gene names	EXPH5, KIAA0624, SLAC2B
Domain Architecture	No domain graphic available
Description	Slp homolog lacking C2 domains b (Exophilin-5).

UN13A_HUMAN
θ value	0.0113563 (rank : 85)	NC score	0.298807 (rank : 80)
Query Neighborhood Hits	248	Target Neighborhood Hits	285	Shared Neighborhood Hits	93
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

OTOF_MOUSE
θ value	0.0148317 (rank : 86)	NC score	0.301763 (rank : 79)
Query Neighborhood Hits	248	Target Neighborhood Hits	196	Shared Neighborhood Hits	85
SwissProt Accessions	Q9ESF1, Q9ESF2	Gene names	Otof, Fer1l2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

PA24D_MOUSE
θ value	0.0148317 (rank : 87)	NC score	0.297996 (rank : 81)
Query Neighborhood Hits	248	Target Neighborhood Hits	100	Shared Neighborhood Hits	79
SwissProt Accessions	Q50L43, Q3TJC5	Gene names	Pla2g4d
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

SYT13_HUMAN
θ value	0.0193708 (rank : 88)	NC score	0.603536 (rank : 44)
Query Neighborhood Hits	248	Target Neighborhood Hits	76	Shared Neighborhood Hits	66
SwissProt Accessions	Q7L8C5, Q9BQS3, Q9H041, Q9P2C0	Gene names	SYT13, KIAA1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

SYT13_MOUSE
θ value	0.0193708 (rank : 89)	NC score	0.595681 (rank : 45)
Query Neighborhood Hits	248	Target Neighborhood Hits	69	Shared Neighborhood Hits	66
SwissProt Accessions	Q9EQT6, Q6ZPR2, Q8BRK6	Gene names	Syt13, Kiaa1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

MDC1_MOUSE
θ value	0.0330416 (rank : 90)	NC score	0.045677 (rank : 171)
Query Neighborhood Hits	248	Target Neighborhood Hits	998	Shared Neighborhood Hits	58
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

RGS3_HUMAN
θ value	0.0330416 (rank : 91)	NC score	0.214851 (rank : 90)
Query Neighborhood Hits	248	Target Neighborhood Hits	1375	Shared Neighborhood Hits	121
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RFIP1_MOUSE
θ value	0.0563607 (rank : 92)	NC score	0.188061 (rank : 103)
Query Neighborhood Hits	248	Target Neighborhood Hits	152	Shared Neighborhood Hits	50
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

UN13B_MOUSE
θ value	0.0563607 (rank : 93)	NC score	0.295820 (rank : 82)
Query Neighborhood Hits	248	Target Neighborhood Hits	210	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

RFIP1_HUMAN
θ value	0.0961366 (rank : 94)	NC score	0.181948 (rank : 105)
Query Neighborhood Hits	248	Target Neighborhood Hits	236	Shared Neighborhood Hits	64
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

UN13B_HUMAN
θ value	0.0961366 (rank : 95)	NC score	0.291828 (rank : 83)
Query Neighborhood Hits	248	Target Neighborhood Hits	217	Shared Neighborhood Hits	88
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

FANCJ_HUMAN
θ value	0.125558 (rank : 96)	NC score	0.023676 (rank : 211)
Query Neighborhood Hits	248	Target Neighborhood Hits	72	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BX63, Q8NCI5	Gene names	BRIP1, BACH1, FANCJ
Domain Architecture	No domain graphic available
Description	Fanconi anemia group J protein (EC 3.6.1.-) (ATP-dependent RNA helicase BRIP1) (Protein FACJ) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1) (BRCA1-associated C-terminal helicase 1).

TGON2_HUMAN
θ value	0.125558 (rank : 97)	NC score	0.051854 (rank : 161)
Query Neighborhood Hits	248	Target Neighborhood Hits	1037	Shared Neighborhood Hits	70
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

ADDB_MOUSE
θ value	0.163984 (rank : 98)	NC score	0.039137 (rank : 177)
Query Neighborhood Hits	248	Target Neighborhood Hits	574	Shared Neighborhood Hits	48
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

JHD2C_HUMAN
θ value	0.163984 (rank : 99)	NC score	0.031107 (rank : 188)
Query Neighborhood Hits	248	Target Neighborhood Hits	279	Shared Neighborhood Hits	28
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

SRRM2_MOUSE
θ value	0.163984 (rank : 100)	NC score	0.071670 (rank : 140)
Query Neighborhood Hits	248	Target Neighborhood Hits	1470	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

BRCA2_HUMAN
θ value	0.21417 (rank : 101)	NC score	0.025188 (rank : 207)
Query Neighborhood Hits	248	Target Neighborhood Hits	202	Shared Neighborhood Hits	12
SwissProt Accessions	P51587, O00183, O15008, Q13879	Gene names	BRCA2, FANCD1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein).

CAF1B_MOUSE
θ value	0.21417 (rank : 102)	NC score	0.015080 (rank : 245)
Query Neighborhood Hits	248	Target Neighborhood Hits	385	Shared Neighborhood Hits	20
SwissProt Accessions	Q9D0N7	Gene names	Chaf1b
Domain Architecture
Description	Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60).

CBP_MOUSE
θ value	0.21417 (rank : 103)	NC score	0.046835 (rank : 170)
Query Neighborhood Hits	248	Target Neighborhood Hits	1051	Shared Neighborhood Hits	54
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

IWS1_HUMAN
θ value	0.21417 (rank : 104)	NC score	0.055929 (rank : 152)
Query Neighborhood Hits	248	Target Neighborhood Hits	1241	Shared Neighborhood Hits	86
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

SOX13_HUMAN
θ value	0.21417 (rank : 105)	NC score	0.022204 (rank : 217)
Query Neighborhood Hits	248	Target Neighborhood Hits	464	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

CK5P2_HUMAN
θ value	0.279714 (rank : 106)	NC score	0.010941 (rank : 272)
Query Neighborhood Hits	248	Target Neighborhood Hits	1433	Shared Neighborhood Hits	44
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

CPNE7_HUMAN
θ value	0.279714 (rank : 107)	NC score	0.152578 (rank : 116)
Query Neighborhood Hits	248	Target Neighborhood Hits	92	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UBL6	Gene names	CPNE7
Domain Architecture
Description	Copine-7 (Copine VII).

SUHW4_HUMAN
θ value	0.279714 (rank : 108)	NC score	0.006039 (rank : 289)
Query Neighborhood Hits	248	Target Neighborhood Hits	860	Shared Neighborhood Hits	28
SwissProt Accessions	Q6N043, Q6MZM6, Q6N085, Q9H0U5, Q9HCI8, Q9NXS0	Gene names	SUHW4, KIAA1584
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

AKAP6_HUMAN
θ value	0.365318 (rank : 109)	NC score	0.024233 (rank : 209)
Query Neighborhood Hits	248	Target Neighborhood Hits	263	Shared Neighborhood Hits	12
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

APXL_HUMAN
θ value	0.365318 (rank : 110)	NC score	0.028637 (rank : 197)
Query Neighborhood Hits	248	Target Neighborhood Hits	553	Shared Neighborhood Hits	30
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

CENPR_HUMAN
θ value	0.365318 (rank : 111)	NC score	0.034134 (rank : 183)
Query Neighborhood Hits	248	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	Q13352, Q13353, Q5RJ42, Q5RJ44, Q5RJ45, Q7KYX2, Q96CD5, Q9UKB6	Gene names	ITGB3BP, CENPR, NRIF3
Domain Architecture	No domain graphic available
Description	Centromere protein R (CENP-R) (Nuclear receptor-interacting factor 3) (Integrin beta-3-binding protein) (Beta3-endonexin).

REPS1_MOUSE
θ value	0.365318 (rank : 112)	NC score	0.025544 (rank : 205)
Query Neighborhood Hits	248	Target Neighborhood Hits	204	Shared Neighborhood Hits	20
SwissProt Accessions	O54916, Q8C9J9, Q99LR8	Gene names	Reps1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

SRRM2_HUMAN
θ value	0.365318 (rank : 113)	NC score	0.065201 (rank : 142)
Query Neighborhood Hits	248	Target Neighborhood Hits	1296	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

WNK4_HUMAN
θ value	0.365318 (rank : 114)	NC score	0.015807 (rank : 243)
Query Neighborhood Hits	248	Target Neighborhood Hits	1043	Shared Neighborhood Hits	33
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

DOCK4_MOUSE
θ value	0.47712 (rank : 115)	NC score	0.023586 (rank : 212)
Query Neighborhood Hits	248	Target Neighborhood Hits	210	Shared Neighborhood Hits	26
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

MINT_HUMAN
θ value	0.47712 (rank : 116)	NC score	0.041415 (rank : 174)
Query Neighborhood Hits	248	Target Neighborhood Hits	1291	Shared Neighborhood Hits	69
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

RTN4_MOUSE
θ value	0.47712 (rank : 117)	NC score	0.027214 (rank : 200)
Query Neighborhood Hits	248	Target Neighborhood Hits	341	Shared Neighborhood Hits	27
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

SAS6_MOUSE
θ value	0.47712 (rank : 118)	NC score	0.011470 (rank : 269)
Query Neighborhood Hits	248	Target Neighborhood Hits	931	Shared Neighborhood Hits	20
SwissProt Accessions	Q80UK7, Q9CYT4	Gene names	Sass6, Sas6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog.

ZSCA5_HUMAN
θ value	0.47712 (rank : 119)	NC score	-0.003329 (rank : 304)
Query Neighborhood Hits	248	Target Neighborhood Hits	862	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BUG6	Gene names	ZSCAN5, ZNF495
Domain Architecture	No domain graphic available
Description	Zinc finger and SCAN domain-containing protein 5 (Zinc finger protein 495).

CBP_HUMAN
θ value	0.62314 (rank : 120)	NC score	0.040369 (rank : 175)
Query Neighborhood Hits	248	Target Neighborhood Hits	941	Shared Neighborhood Hits	47
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

NEB1_HUMAN
θ value	0.62314 (rank : 121)	NC score	0.020582 (rank : 228)
Query Neighborhood Hits	248	Target Neighborhood Hits	829	Shared Neighborhood Hits	38
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

NPBL_MOUSE
θ value	0.62314 (rank : 122)	NC score	0.042326 (rank : 173)
Query Neighborhood Hits	248	Target Neighborhood Hits	1041	Shared Neighborhood Hits	71
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PARG_MOUSE
θ value	0.62314 (rank : 123)	NC score	0.029780 (rank : 193)
Query Neighborhood Hits	248	Target Neighborhood Hits	54	Shared Neighborhood Hits	8
SwissProt Accessions	O88622, Q80YQ6, Q8CB72	Gene names	Parg
Domain Architecture	No domain graphic available
Description	Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143).

RNF38_HUMAN
θ value	0.62314 (rank : 124)	NC score	0.022711 (rank : 215)
Query Neighborhood Hits	248	Target Neighborhood Hits	155	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H0F5, Q8N0Y0	Gene names	RNF38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

ZDHC5_HUMAN
θ value	0.62314 (rank : 125)	NC score	0.016328 (rank : 240)
Query Neighborhood Hits	248	Target Neighborhood Hits	106	Shared Neighborhood Hits	6
SwissProt Accessions	Q9C0B5, Q6ZMF0, Q8TAK8, Q9H923, Q9UFI7	Gene names	ZDHHC5, KIAA1748, ZNF375
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC5 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 5) (DHHC-5) (Zinc finger protein 375).

BBX_MOUSE
θ value	0.813845 (rank : 126)	NC score	0.024280 (rank : 208)
Query Neighborhood Hits	248	Target Neighborhood Hits	152	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VBW5, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VI48, Q8VI49, Q8VI50, Q9CS94	Gene names	Bbx, Hbp2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

INVS_MOUSE
θ value	0.813845 (rank : 127)	NC score	0.008992 (rank : 277)
Query Neighborhood Hits	248	Target Neighborhood Hits	609	Shared Neighborhood Hits	23
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

JHD2A_MOUSE
θ value	0.813845 (rank : 128)	NC score	0.032671 (rank : 184)
Query Neighborhood Hits	248	Target Neighborhood Hits	123	Shared Neighborhood Hits	17
SwissProt Accessions	Q6PCM1, Q2MJQ6, Q3TKW8, Q3UML3, Q6ZQ57, Q8K2J6, Q8K2K4, Q8R350	Gene names	Jmjd1a, Jhdm2a, Kiaa0742
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2A (EC 1.14.11.-) (Jumonji domain-containing protein 1A).

RAI1_MOUSE
θ value	0.813845 (rank : 129)	NC score	0.027716 (rank : 198)
Query Neighborhood Hits	248	Target Neighborhood Hits	344	Shared Neighborhood Hits	23
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RNF38_MOUSE
θ value	0.813845 (rank : 130)	NC score	0.021907 (rank : 220)
Query Neighborhood Hits	248	Target Neighborhood Hits	153	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BI21, Q6P5B1	Gene names	Rnf38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

ALMS1_MOUSE
θ value	1.06291 (rank : 131)	NC score	0.021435 (rank : 223)
Query Neighborhood Hits	248	Target Neighborhood Hits	181	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K4E0, Q6A084, Q8C9N9	Gene names	Alms1, Kiaa0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1 homolog.

DMP1_HUMAN
θ value	1.06291 (rank : 132)	NC score	0.034314 (rank : 182)
Query Neighborhood Hits	248	Target Neighborhood Hits	491	Shared Neighborhood Hits	42
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

MAP2_MOUSE
θ value	1.06291 (rank : 133)	NC score	0.028911 (rank : 196)
Query Neighborhood Hits	248	Target Neighborhood Hits	342	Shared Neighborhood Hits	36
SwissProt Accessions	P20357	Gene names	Map2, Mtap2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2).

ZDHC5_MOUSE
θ value	1.06291 (rank : 134)	NC score	0.016262 (rank : 241)
Query Neighborhood Hits	248	Target Neighborhood Hits	113	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VDZ4, Q69ZB5, Q8R2X7	Gene names	Zdhhc5, Kiaa1748
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC5 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 5) (DHHC-5).

ZN592_MOUSE
θ value	1.06291 (rank : 135)	NC score	0.001357 (rank : 302)
Query Neighborhood Hits	248	Target Neighborhood Hits	768	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BHZ4, Q80XM1	Gene names	Znf592, Kiaa0211, Zfp592
Domain Architecture	No domain graphic available
Description	Zinc finger protein 592 (Zfp-592).

CCD93_HUMAN
θ value	1.38821 (rank : 136)	NC score	0.011470 (rank : 268)
Query Neighborhood Hits	248	Target Neighborhood Hits	600	Shared Neighborhood Hits	21
SwissProt Accessions	Q567U6, Q4LE78, Q53TJ2, Q8TBX5, Q9H6R5, Q9NV15	Gene names	CCDC93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

CTR9_MOUSE
θ value	1.38821 (rank : 137)	NC score	0.029346 (rank : 194)
Query Neighborhood Hits	248	Target Neighborhood Hits	427	Shared Neighborhood Hits	31
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

JHD2A_HUMAN
θ value	1.38821 (rank : 138)	NC score	0.029056 (rank : 195)
Query Neighborhood Hits	248	Target Neighborhood Hits	118	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y4C1, Q53S72, Q68D47, Q68UT9, Q6N050, Q8IY08	Gene names	JMJD1A, JHDM2A, JMJD1, KIAA0742
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2A (EC 1.14.11.-) (Jumonji domain-containing protein 1A).

K0240_HUMAN
θ value	1.38821 (rank : 139)	NC score	0.026198 (rank : 203)
Query Neighborhood Hits	248	Target Neighborhood Hits	96	Shared Neighborhood Hits	12
SwissProt Accessions	Q6AI39, Q5TFZ3, Q92514	Gene names	KIAA0240
Domain Architecture	No domain graphic available
Description	Protein KIAA0240.

LPIN2_HUMAN
θ value	1.38821 (rank : 140)	NC score	0.021247 (rank : 224)
Query Neighborhood Hits	248	Target Neighborhood Hits	117	Shared Neighborhood Hits	15
SwissProt Accessions	Q92539	Gene names	LPIN2, KIAA0249
Domain Architecture	No domain graphic available
Description	Lipin-2.

NCOA6_HUMAN
θ value	1.38821 (rank : 141)	NC score	0.032148 (rank : 186)
Query Neighborhood Hits	248	Target Neighborhood Hits	1202	Shared Neighborhood Hits	53
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

RHG07_HUMAN
θ value	1.38821 (rank : 142)	NC score	0.012329 (rank : 261)
Query Neighborhood Hits	248	Target Neighborhood Hits	108	Shared Neighborhood Hits	7
SwissProt Accessions	Q96QB1, O14868, O43199, Q9C0E0	Gene names	DLC1, ARHGAP7, KIAA1723, STARD12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

RHG07_MOUSE
θ value	1.38821 (rank : 143)	NC score	0.012054 (rank : 262)
Query Neighborhood Hits	248	Target Neighborhood Hits	103	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

AFF1_MOUSE
θ value	1.81305 (rank : 144)	NC score	0.026612 (rank : 202)
Query Neighborhood Hits	248	Target Neighborhood Hits	351	Shared Neighborhood Hits	35
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

DOCK4_HUMAN
θ value	1.81305 (rank : 145)	NC score	0.022750 (rank : 214)
Query Neighborhood Hits	248	Target Neighborhood Hits	237	Shared Neighborhood Hits	24
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

DYH9_HUMAN
θ value	1.81305 (rank : 146)	NC score	0.008669 (rank : 280)
Query Neighborhood Hits	248	Target Neighborhood Hits	291	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NYC9, O95494, Q9NQ28	Gene names	DNAH9, DNAH17L, DNAL1
Domain Architecture
Description	Ciliary dynein heavy chain 9 (Axonemal beta dynein heavy chain 9).

GASP1_MOUSE
θ value	1.81305 (rank : 147)	NC score	0.014562 (rank : 246)
Query Neighborhood Hits	248	Target Neighborhood Hits	169	Shared Neighborhood Hits	19
SwissProt Accessions	Q5U4C1, Q8BKR8, Q8BUN4, Q8BYK9, Q8CHF4, Q8R095	Gene names	Gprasp1, Kiaa0443
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 1 (GASP-1).

GP156_HUMAN
θ value	1.81305 (rank : 148)	NC score	0.016188 (rank : 242)
Query Neighborhood Hits	248	Target Neighborhood Hits	84	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NFN8, Q86SN6	Gene names	GPR156, GABABL, PGR28
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor) (G-protein coupled receptor PGR28).

ITSN1_HUMAN
θ value	1.81305 (rank : 149)	NC score	0.104466 (rank : 131)
Query Neighborhood Hits	248	Target Neighborhood Hits	1757	Shared Neighborhood Hits	112
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN1_MOUSE
θ value	1.81305 (rank : 150)	NC score	0.106554 (rank : 129)
Query Neighborhood Hits	248	Target Neighborhood Hits	1669	Shared Neighborhood Hits	119
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

MYRIP_MOUSE
θ value	1.81305 (rank : 151)	NC score	0.220493 (rank : 89)
Query Neighborhood Hits	248	Target Neighborhood Hits	207	Shared Neighborhood Hits	41
SwissProt Accessions	Q8K3I4, Q8CFC0, Q8K4H5	Gene names	Myrip, Slac2c
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

RIF1_MOUSE
θ value	1.81305 (rank : 152)	NC score	0.022012 (rank : 218)
Query Neighborhood Hits	248	Target Neighborhood Hits	315	Shared Neighborhood Hits	34
SwissProt Accessions	Q6PR54, Q6T8D9, Q7TPD8, Q8BTU2, Q8C408, Q9CS77	Gene names	Rif1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1).

BCAS1_HUMAN
θ value	2.36792 (rank : 153)	NC score	0.021634 (rank : 222)
Query Neighborhood Hits	248	Target Neighborhood Hits	133	Shared Neighborhood Hits	21
SwissProt Accessions	O75363, Q68CZ3	Gene names	BCAS1, AIBC1, NABC1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 1 (Novel amplified in breast cancer 1) (Amplified and overexpressed in breast cancer).

CEND1_HUMAN
θ value	2.36792 (rank : 154)	NC score	0.013205 (rank : 257)
Query Neighborhood Hits	248	Target Neighborhood Hits	284	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

CPNE8_HUMAN
θ value	2.36792 (rank : 155)	NC score	0.155595 (rank : 115)
Query Neighborhood Hits	248	Target Neighborhood Hits	86	Shared Neighborhood Hits	62
SwissProt Accessions	Q86YQ8, Q2TB41	Gene names	CPNE8
Domain Architecture
Description	Copine-8 (Copine VIII).

CPNE8_MOUSE
θ value	2.36792 (rank : 156)	NC score	0.152015 (rank : 117)
Query Neighborhood Hits	248	Target Neighborhood Hits	85	Shared Neighborhood Hits	62
SwissProt Accessions	Q9DC53, Q9CUZ8	Gene names	Cpne8
Domain Architecture
Description	Copine-8 (Copine VIII).

ELOA1_MOUSE
θ value	2.36792 (rank : 157)	NC score	0.020315 (rank : 229)
Query Neighborhood Hits	248	Target Neighborhood Hits	152	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CB77, Q80VB2, Q9R0Q5	Gene names	Tceb3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

FIP1_HUMAN
θ value	2.36792 (rank : 158)	NC score	0.020116 (rank : 231)
Query Neighborhood Hits	248	Target Neighborhood Hits	118	Shared Neighborhood Hits	15
SwissProt Accessions	Q6UN15, Q499Y4, Q49AU3, Q7Z608, Q8WVN3, Q96F80, Q9H077	Gene names	FIP1L1, FIP1, RHE
Domain Architecture	No domain graphic available
Description	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1) (Factor interacting with PAP) (hFip1) (Rearranged in hypereosinophilia).

GLIS3_HUMAN
θ value	2.36792 (rank : 159)	NC score	-0.004984 (rank : 305)
Query Neighborhood Hits	248	Target Neighborhood Hits	758	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NEA6	Gene names	GLIS3, ZNF515
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3) (Zinc finger protein 515).

ITSN2_HUMAN
θ value	2.36792 (rank : 160)	NC score	0.149251 (rank : 118)
Query Neighborhood Hits	248	Target Neighborhood Hits	1173	Shared Neighborhood Hits	95
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

K0240_MOUSE
θ value	2.36792 (rank : 161)	NC score	0.032225 (rank : 185)
Query Neighborhood Hits	248	Target Neighborhood Hits	211	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CHH5	Gene names	Kiaa0240
Domain Architecture	No domain graphic available
Description	Protein KIAA0240.

MFAP1_HUMAN
θ value	2.36792 (rank : 162)	NC score	0.018800 (rank : 234)
Query Neighborhood Hits	248	Target Neighborhood Hits	321	Shared Neighborhood Hits	18
SwissProt Accessions	P55081	Gene names	MFAP1
Domain Architecture
Description	Microfibrillar-associated protein 1.

PARG_HUMAN
θ value	2.36792 (rank : 163)	NC score	0.027306 (rank : 199)
Query Neighborhood Hits	248	Target Neighborhood Hits	97	Shared Neighborhood Hits	12
SwissProt Accessions	Q86W56, Q6E4P6, Q6E4P7, Q7Z742, Q9Y4W7	Gene names	PARG
Domain Architecture	No domain graphic available
Description	Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143).

TR150_MOUSE
θ value	2.36792 (rank : 164)	NC score	0.020989 (rank : 225)
Query Neighborhood Hits	248	Target Neighborhood Hits	468	Shared Neighborhood Hits	39
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

UN13D_HUMAN
θ value	2.36792 (rank : 165)	NC score	0.442741 (rank : 62)
Query Neighborhood Hits	248	Target Neighborhood Hits	117	Shared Neighborhood Hits	87
SwissProt Accessions	Q70J99, Q9H7K5	Gene names	UNC13D
Domain Architecture	No domain graphic available
Description	Unc-13 homolog D (Munc13-4).

US6NL_HUMAN
θ value	2.36792 (rank : 166)	NC score	0.018421 (rank : 237)
Query Neighborhood Hits	248	Target Neighborhood Hits	201	Shared Neighborhood Hits	15
SwissProt Accessions	Q92738, Q15400, Q7L0K9	Gene names	USP6NL, KIAA0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN- tre).

ALO17_HUMAN
θ value	3.0926 (rank : 167)	NC score	0.031100 (rank : 189)
Query Neighborhood Hits	248	Target Neighborhood Hits	317	Shared Neighborhood Hits	25
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

DNM3A_MOUSE
θ value	3.0926 (rank : 168)	NC score	0.010916 (rank : 273)
Query Neighborhood Hits	248	Target Neighborhood Hits	91	Shared Neighborhood Hits	7
SwissProt Accessions	O88508, Q3UH24, Q8CJ60, Q922J0, Q9CSE1	Gene names	Dnmt3a
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase MmuIIIA) (DNA MTase MmuIIIA) (M.MmuIIIA).

GRIPE_MOUSE
θ value	3.0926 (rank : 169)	NC score	0.010903 (rank : 274)
Query Neighborhood Hits	248	Target Neighborhood Hits	70	Shared Neighborhood Hits	5
SwissProt Accessions	Q6GYP7, Q6GYP6, Q6ZQ28, Q8BNJ5, Q8C9G8, Q8CIW4, Q9JMC4	Gene names	Garnl1, Kiaa0884, Tulip1
Domain Architecture	No domain graphic available
Description	GTPase-activating RapGAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

HS105_HUMAN
θ value	3.0926 (rank : 170)	NC score	0.008728 (rank : 279)
Query Neighborhood Hits	248	Target Neighborhood Hits	209	Shared Neighborhood Hits	20
SwissProt Accessions	Q92598, O95739, Q5TBM6, Q5TBM8, Q9UPC4	Gene names	HSPH1, HSP105, HSP110, KIAA0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock 110 kDa protein) (Antigen NY- CO-25).

LIPB2_HUMAN
θ value	3.0926 (rank : 171)	NC score	0.005090 (rank : 291)
Query Neighborhood Hits	248	Target Neighborhood Hits	599	Shared Neighborhood Hits	15
SwissProt Accessions	Q8ND30, O75337, Q8WW26	Gene names	PPFIBP2
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2).

MFAP1_MOUSE
θ value	3.0926 (rank : 172)	NC score	0.017158 (rank : 239)
Query Neighborhood Hits	248	Target Neighborhood Hits	353	Shared Neighborhood Hits	18
SwissProt Accessions	Q9CQU1, Q3TU29, Q8CCL1, Q9CSJ5	Gene names	Mfap1
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 1.

OGFR_HUMAN
θ value	3.0926 (rank : 173)	NC score	0.039113 (rank : 178)
Query Neighborhood Hits	248	Target Neighborhood Hits	1582	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PA24E_HUMAN
θ value	3.0926 (rank : 174)	NC score	0.173544 (rank : 108)
Query Neighborhood Hits	248	Target Neighborhood Hits	89	Shared Neighborhood Hits	66
SwissProt Accessions	Q3MJ16, Q6ZSC0	Gene names	PLA2G4E
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

SRPK1_HUMAN
θ value	3.0926 (rank : 175)	NC score	0.001695 (rank : 301)
Query Neighborhood Hits	248	Target Neighborhood Hits	706	Shared Neighborhood Hits	17
SwissProt Accessions	Q96SB4, Q12890, Q5R364, Q5R365, Q8IY12	Gene names	SRPK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK1 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 1) (SR-protein-specific kinase 1) (SFRS protein kinase 1).

TRI66_HUMAN
θ value	3.0926 (rank : 176)	NC score	0.012463 (rank : 260)
Query Neighborhood Hits	248	Target Neighborhood Hits	479	Shared Neighborhood Hits	19
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TXND2_MOUSE
θ value	3.0926 (rank : 177)	NC score	0.039792 (rank : 176)
Query Neighborhood Hits	248	Target Neighborhood Hits	828	Shared Neighborhood Hits	68
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

XRCC1_MOUSE
θ value	3.0926 (rank : 178)	NC score	0.020831 (rank : 227)
Query Neighborhood Hits	248	Target Neighborhood Hits	242	Shared Neighborhood Hits	18
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

ZO2_HUMAN
θ value	3.0926 (rank : 179)	NC score	0.013112 (rank : 258)
Query Neighborhood Hits	248	Target Neighborhood Hits	289	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ADDB_HUMAN
θ value	4.03905 (rank : 180)	NC score	0.021852 (rank : 221)
Query Neighborhood Hits	248	Target Neighborhood Hits	142	Shared Neighborhood Hits	18
SwissProt Accessions	P35612, Q13482, Q16412, Q59G82, Q5U5P4, Q6P0P2, Q6PGQ4, Q7Z688, Q7Z689, Q7Z690, Q7Z691	Gene names	ADD2, ADDB
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta).

BAIP3_HUMAN
θ value	4.03905 (rank : 181)	NC score	0.410074 (rank : 67)
Query Neighborhood Hits	248	Target Neighborhood Hits	108	Shared Neighborhood Hits	82
SwissProt Accessions	O94812, O94839, Q2M226, Q658J2, Q76N05, Q96RZ3, Q9UJK1	Gene names	BAIAP3, KIAA0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

BAIP3_MOUSE
θ value	4.03905 (rank : 182)	NC score	0.408301 (rank : 68)
Query Neighborhood Hits	248	Target Neighborhood Hits	112	Shared Neighborhood Hits	86
SwissProt Accessions	Q80TT2, Q6RUT4	Gene names	Baiap3, Gm937, Kiaa0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

BAT3_HUMAN
θ value	4.03905 (rank : 183)	NC score	0.023761 (rank : 210)
Query Neighborhood Hits	248	Target Neighborhood Hits	490	Shared Neighborhood Hits	25
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

BRWD1_HUMAN
θ value	4.03905 (rank : 184)	NC score	0.005121 (rank : 290)
Query Neighborhood Hits	248	Target Neighborhood Hits	448	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NSI6, O43721, Q5R2V0, Q5R2V1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1	Gene names	BRWD1, C21orf107, WDR9
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

CD2L1_HUMAN
θ value	4.03905 (rank : 185)	NC score	0.014296 (rank : 248)
Query Neighborhood Hits	248	Target Neighborhood Hits	1467	Shared Neighborhood Hits	58
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

CD2L2_HUMAN
θ value	4.03905 (rank : 186)	NC score	0.013486 (rank : 255)
Query Neighborhood Hits	248	Target Neighborhood Hits	1439	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

CYTSA_HUMAN
θ value	4.03905 (rank : 187)	NC score	0.002911 (rank : 297)
Query Neighborhood Hits	248	Target Neighborhood Hits	1138	Shared Neighborhood Hits	33
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

CYTSA_MOUSE
θ value	4.03905 (rank : 188)	NC score	0.002351 (rank : 298)
Query Neighborhood Hits	248	Target Neighborhood Hits	1104	Shared Neighborhood Hits	29
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

GAB1_HUMAN
θ value	4.03905 (rank : 189)	NC score	0.015522 (rank : 244)
Query Neighborhood Hits	248	Target Neighborhood Hits	279	Shared Neighborhood Hits	20
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

MYOZ3_MOUSE
θ value	4.03905 (rank : 190)	NC score	0.011905 (rank : 263)
Query Neighborhood Hits	248	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R4E4	Gene names	Myoz3
Domain Architecture	No domain graphic available
Description	Myozenin-3 (Calsarcin-3) (FATZ-related protein 3).

N4BP2_HUMAN
θ value	4.03905 (rank : 191)	NC score	0.013829 (rank : 251)
Query Neighborhood Hits	248	Target Neighborhood Hits	107	Shared Neighborhood Hits	7
SwissProt Accessions	Q86UW6, Q9NVK2, Q9P2D4	Gene names	N4BP2, B3BP, KIAA1413
Domain Architecture
Description	NEDD4-binding protein 2 (EC 3.-.-.-) (N4BP2) (BCL-3-binding protein).

OS9_HUMAN
θ value	4.03905 (rank : 192)	NC score	0.018648 (rank : 235)
Query Neighborhood Hits	248	Target Neighborhood Hits	134	Shared Neighborhood Hits	14
SwissProt Accessions	Q13438, O00579	Gene names	OS9
Domain Architecture	No domain graphic available
Description	Protein OS-9 precursor (Amplified in osteosarcoma 9).

PI4KB_HUMAN
θ value	4.03905 (rank : 193)	NC score	0.052355 (rank : 159)
Query Neighborhood Hits	248	Target Neighborhood Hits	79	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UBF8, O15096, P78405, Q9BWR6	Gene names	PIK4CB, PI4KB
Domain Architecture
Description	Phosphatidylinositol 4-kinase beta (EC 2.7.1.67) (PtdIns 4-kinase beta) (PI4Kbeta) (PI4K-beta) (NPIK) (PI4K92).

PPIG_HUMAN
θ value	4.03905 (rank : 194)	NC score	0.013532 (rank : 254)
Query Neighborhood Hits	248	Target Neighborhood Hits	670	Shared Neighborhood Hits	55
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

SOS1_HUMAN
θ value	4.03905 (rank : 195)	NC score	0.011162 (rank : 271)
Query Neighborhood Hits	248	Target Neighborhood Hits	274	Shared Neighborhood Hits	21
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

TACT_HUMAN
θ value	4.03905 (rank : 196)	NC score	0.013966 (rank : 250)
Query Neighborhood Hits	248	Target Neighborhood Hits	100	Shared Neighborhood Hits	4
SwissProt Accessions	P40200	Gene names	CD96
Domain Architecture	No domain graphic available
Description	T-cell surface protein tactile precursor (T cell-activated increased late expression protein) (CD96 antigen).

VGFR2_MOUSE
θ value	4.03905 (rank : 197)	NC score	0.007338 (rank : 287)
Query Neighborhood Hits	248	Target Neighborhood Hits	1089	Shared Neighborhood Hits	17
SwissProt Accessions	P35918	Gene names	Kdr, Flk-1, Flk1
Domain Architecture
Description	Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) (Kinase NYK) (CD309 antigen).

ZG14_MOUSE
θ value	4.03905 (rank : 198)	NC score	0.014155 (rank : 249)
Query Neighborhood Hits	248	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D1C9, Q3TWT8, Q8CCK8	Gene names
Domain Architecture	No domain graphic available
Description	Gastric cancer antigen Zg14 homolog.

AP3B1_MOUSE
θ value	5.27518 (rank : 199)	NC score	0.011384 (rank : 270)
Query Neighborhood Hits	248	Target Neighborhood Hits	302	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

BAT3_MOUSE
θ value	5.27518 (rank : 200)	NC score	0.025577 (rank : 204)
Query Neighborhood Hits	248	Target Neighborhood Hits	518	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

CAC1E_MOUSE
θ value	5.27518 (rank : 201)	NC score	0.004392 (rank : 293)
Query Neighborhood Hits	248	Target Neighborhood Hits	167	Shared Neighborhood Hits	14
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CD2L1_MOUSE
θ value	5.27518 (rank : 202)	NC score	0.018246 (rank : 238)
Query Neighborhood Hits	248	Target Neighborhood Hits	1463	Shared Neighborhood Hits	57
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

CI039_HUMAN
θ value	5.27518 (rank : 203)	NC score	0.006568 (rank : 288)
Query Neighborhood Hits	248	Target Neighborhood Hits	1171	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

DMP1_MOUSE
θ value	5.27518 (rank : 204)	NC score	0.034584 (rank : 181)
Query Neighborhood Hits	248	Target Neighborhood Hits	498	Shared Neighborhood Hits	47
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

ELOA1_HUMAN
θ value	5.27518 (rank : 205)	NC score	0.019911 (rank : 232)
Query Neighborhood Hits	248	Target Neighborhood Hits	388	Shared Neighborhood Hits	32
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

K0460_MOUSE
θ value	5.27518 (rank : 206)	NC score	0.020152 (rank : 230)
Query Neighborhood Hits	248	Target Neighborhood Hits	374	Shared Neighborhood Hits	29
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

LEO1_HUMAN
θ value	5.27518 (rank : 207)	NC score	0.031697 (rank : 187)
Query Neighborhood Hits	248	Target Neighborhood Hits	958	Shared Neighborhood Hits	53
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

MELPH_HUMAN
θ value	5.27518 (rank : 208)	NC score	0.209376 (rank : 94)
Query Neighborhood Hits	248	Target Neighborhood Hits	145	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BV36, Q9HA71	Gene names	MLPH, SLAC2A
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Synaptotagmin-like protein 2a) (Slp homolog lacking C2 domains a).

MINT_MOUSE
θ value	5.27518 (rank : 209)	NC score	0.038669 (rank : 180)
Query Neighborhood Hits	248	Target Neighborhood Hits	1514	Shared Neighborhood Hits	78
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MLL3_MOUSE
θ value	5.27518 (rank : 210)	NC score	0.023390 (rank : 213)
Query Neighborhood Hits	248	Target Neighborhood Hits	1399	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MO4L2_HUMAN
θ value	5.27518 (rank : 211)	NC score	0.011612 (rank : 267)
Query Neighborhood Hits	248	Target Neighborhood Hits	90	Shared Neighborhood Hits	8
SwissProt Accessions	Q15014, Q567V0, Q8J026	Gene names	MORF4L2, KIAA0026, MRGX
Domain Architecture
Description	Mortality factor 4-like protein 2 (MORF-related gene X protein) (Transcription factor-like protein MRGX) (MSL3-2 protein).

NHEJ1_MOUSE
θ value	5.27518 (rank : 212)	NC score	0.013328 (rank : 256)
Query Neighborhood Hits	248	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	Q3KNJ2, Q99JK0, Q9D9U0	Gene names	Nhej1, Xlf
Domain Architecture	No domain graphic available
Description	Non-homologous end-joining factor 1 (Protein cernunnos) (XRCC4-like factor).

RBBP6_MOUSE
θ value	5.27518 (rank : 213)	NC score	0.038811 (rank : 179)
Query Neighborhood Hits	248	Target Neighborhood Hits	1014	Shared Neighborhood Hits	61
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

TGON1_MOUSE
θ value	5.27518 (rank : 214)	NC score	0.029954 (rank : 192)
Query Neighborhood Hits	248	Target Neighborhood Hits	243	Shared Neighborhood Hits	31
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

U2AFM_HUMAN
θ value	5.27518 (rank : 215)	NC score	0.007679 (rank : 284)
Query Neighborhood Hits	248	Target Neighborhood Hits	577	Shared Neighborhood Hits	21
SwissProt Accessions	Q15696	Gene names	ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (NY-REN-20 antigen).

AKA11_HUMAN
θ value	6.88961 (rank : 216)	NC score	0.011705 (rank : 266)
Query Neighborhood Hits	248	Target Neighborhood Hits	57	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UKA4, O75124, Q9NUK7	Gene names	AKAP11, AKAP220, KIAA0629
Domain Architecture
Description	A-kinase anchor protein 11 (Protein kinase A-anchoring protein 11) (PRKA11) (A kinase anchor protein 220 kDa) (AKAP 220) (hAKAP220).

ARI5B_HUMAN
θ value	6.88961 (rank : 217)	NC score	0.022329 (rank : 216)
Query Neighborhood Hits	248	Target Neighborhood Hits	328	Shared Neighborhood Hits	31
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

C8AP2_MOUSE
θ value	6.88961 (rank : 218)	NC score	0.014412 (rank : 247)
Query Neighborhood Hits	248	Target Neighborhood Hits	405	Shared Neighborhood Hits	37
SwissProt Accessions	Q9WUF3, Q9CSW2	Gene names	Casp8ap2, Flash
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

DDX21_HUMAN
θ value	6.88961 (rank : 219)	NC score	0.003575 (rank : 295)
Query Neighborhood Hits	248	Target Neighborhood Hits	308	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

FA35A_MOUSE
θ value	6.88961 (rank : 220)	NC score	0.012967 (rank : 259)
Query Neighborhood Hits	248	Target Neighborhood Hits	54	Shared Neighborhood Hits	8
SwissProt Accessions	Q3UEN2	Gene names	Fam35a
Domain Architecture	No domain graphic available
Description	Protein FAM35A.

HMG1X_HUMAN
θ value	6.88961 (rank : 221)	NC score	0.004875 (rank : 292)
Query Neighborhood Hits	248	Target Neighborhood Hits	97	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UGV6	Gene names	HMG1L10
Domain Architecture
Description	High mobility group protein 1-like 10 (HMG-1L10).

MCPH1_HUMAN
θ value	6.88961 (rank : 222)	NC score	0.009716 (rank : 276)
Query Neighborhood Hits	248	Target Neighborhood Hits	85	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NEM0, Q66GU1, Q9H9C7	Gene names	MCPH1
Domain Architecture
Description	Microcephalin.

NFM_HUMAN
θ value	6.88961 (rank : 223)	NC score	0.011864 (rank : 265)
Query Neighborhood Hits	248	Target Neighborhood Hits	1328	Shared Neighborhood Hits	68
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

PRCC_HUMAN
θ value	6.88961 (rank : 224)	NC score	0.018458 (rank : 236)
Query Neighborhood Hits	248	Target Neighborhood Hits	109	Shared Neighborhood Hits	7
SwissProt Accessions	Q92733, O00665, O00724	Gene names	PRCC, TPRC
Domain Architecture	No domain graphic available
Description	Proline-rich protein PRCC (Papillary renal cell carcinoma translocation-associated gene protein).

SRRM1_HUMAN
θ value	6.88961 (rank : 225)	NC score	0.051572 (rank : 162)
Query Neighborhood Hits	248	Target Neighborhood Hits	690	Shared Neighborhood Hits	51
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

TEX15_HUMAN
θ value	6.88961 (rank : 226)	NC score	0.013534 (rank : 253)
Query Neighborhood Hits	248	Target Neighborhood Hits	174	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BXT5	Gene names	TEX15
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 15 protein.

ADDA_HUMAN
θ value	8.99809 (rank : 227)	NC score	0.022002 (rank : 219)
Query Neighborhood Hits	248	Target Neighborhood Hits	108	Shared Neighborhood Hits	16
SwissProt Accessions	P35611, Q13734, Q14729, Q16156, Q9UJB6	Gene names	ADD1, ADDA
Domain Architecture
Description	Alpha-adducin (Erythrocyte adducin subunit alpha).

ATX2_HUMAN
θ value	8.99809 (rank : 228)	NC score	0.020905 (rank : 226)
Query Neighborhood Hits	248	Target Neighborhood Hits	375	Shared Neighborhood Hits	29
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

ATX2_MOUSE
θ value	8.99809 (rank : 229)	NC score	0.019042 (rank : 233)
Query Neighborhood Hits	248	Target Neighborhood Hits	445	Shared Neighborhood Hits	33
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

BUB1_HUMAN
θ value	8.99809 (rank : 230)	NC score	0.010597 (rank : 275)
Query Neighborhood Hits	248	Target Neighborhood Hits	543	Shared Neighborhood Hits	16
SwissProt Accessions	O43683, O43430, O43643, O60626	Gene names	BUB1, BUB1L
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 (EC 2.7.11.1) (hBUB1) (BUB1A).

CAC1E_HUMAN
θ value	8.99809 (rank : 231)	NC score	0.003851 (rank : 294)
Query Neighborhood Hits	248	Target Neighborhood Hits	148	Shared Neighborhood Hits	11
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAF1A_HUMAN
θ value	8.99809 (rank : 232)	NC score	0.008879 (rank : 278)
Query Neighborhood Hits	248	Target Neighborhood Hits	750	Shared Neighborhood Hits	31
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

DMXL2_HUMAN
θ value	8.99809 (rank : 233)	NC score	0.001833 (rank : 300)
Query Neighborhood Hits	248	Target Neighborhood Hits	374	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TDJ6, O94938	Gene names	DMXL2, KIAA0856
Domain Architecture	No domain graphic available
Description	Protein DmX-like 2 (Rabconnectin-3).

GLU2B_HUMAN
θ value	8.99809 (rank : 234)	NC score	0.025478 (rank : 206)
Query Neighborhood Hits	248	Target Neighborhood Hits	377	Shared Neighborhood Hits	27
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

GLUD1_MOUSE
θ value	8.99809 (rank : 235)	NC score	0.007997 (rank : 282)
Query Neighborhood Hits	248	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CIX8	Gene names	Gluld1, Lgs
Domain Architecture	No domain graphic available
Description	Glutamate--ammonia ligase domain-containing protein 1 (Lengsin) (Lens glutamine synthase-like).

HEM1_MOUSE
θ value	8.99809 (rank : 236)	NC score	0.007972 (rank : 283)
Query Neighborhood Hits	248	Target Neighborhood Hits	66	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VC19, Q64453	Gene names	Alas1
Domain Architecture	No domain graphic available
Description	5-aminolevulinate synthase, nonspecific, mitochondrial precursor (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta-aminolevulinate synthase) (Delta-ALA synthetase) (ALAS-H).

MAP1B_HUMAN
θ value	8.99809 (rank : 237)	NC score	0.030331 (rank : 191)
Query Neighborhood Hits	248	Target Neighborhood Hits	903	Shared Neighborhood Hits	64
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MK10_MOUSE
θ value	8.99809 (rank : 238)	NC score	0.007359 (rank : 286)
Query Neighborhood Hits	248	Target Neighborhood Hits	849	Shared Neighborhood Hits	16
SwissProt Accessions	Q61831, Q9R0U6	Gene names	Mapk10, Jnk3, Prkm10, Serk2
Domain Architecture
Description	Mitogen-activated protein kinase 10 (EC 2.7.11.24) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3) (MAP kinase p49 3F12).

NASP_HUMAN
θ value	8.99809 (rank : 239)	NC score	0.030805 (rank : 190)
Query Neighborhood Hits	248	Target Neighborhood Hits	709	Shared Neighborhood Hits	50
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

NIPBL_HUMAN
θ value	8.99809 (rank : 240)	NC score	0.042354 (rank : 172)
Query Neighborhood Hits	248	Target Neighborhood Hits	1311	Shared Neighborhood Hits	83
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NOL8_HUMAN
θ value	8.99809 (rank : 241)	NC score	0.011872 (rank : 264)
Query Neighborhood Hits	248	Target Neighborhood Hits	297	Shared Neighborhood Hits	25
SwissProt Accessions	Q76FK4, Q5TCC7, Q5TCC8, Q5TCD3, Q5TCD5, Q5TCD6, Q5TCD7, Q76D35, Q7L3E2, Q9H586, Q9H795, Q9H7W7, Q9H9J6, Q9NWA4, Q9NWM4	Gene names	NOL8, NOP132
Domain Architecture	No domain graphic available
Description	Nucleolar protein 8 (Nucleolar protein Nop132).

NPTX1_MOUSE
θ value	8.99809 (rank : 242)	NC score	0.003232 (rank : 296)
Query Neighborhood Hits	248	Target Neighborhood Hits	67	Shared Neighborhood Hits	2
SwissProt Accessions	Q62443	Gene names	Nptx1
Domain Architecture
Description	Neuronal pentraxin-1 precursor (NP1) (Neuronal pentraxin I) (NP-I).

NUP50_MOUSE
θ value	8.99809 (rank : 243)	NC score	0.007574 (rank : 285)
Query Neighborhood Hits	248	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JIH2, Q9CU02, Q9JK85	Gene names	Nup50, Npap60
Domain Architecture
Description	Nucleoporin 50 kDa (Nuclear pore-associated protein 60 kDa-like).

RIMS3_MOUSE
θ value	8.99809 (rank : 244)	NC score	0.389863 (rank : 70)
Query Neighborhood Hits	248	Target Neighborhood Hits	67	Shared Neighborhood Hits	65
SwissProt Accessions	Q80U57	Gene names	Rims3, Kiaa0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

RYR1_HUMAN
θ value	8.99809 (rank : 245)	NC score	0.008102 (rank : 281)
Query Neighborhood Hits	248	Target Neighborhood Hits	303	Shared Neighborhood Hits	19
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

SALL3_HUMAN
θ value	8.99809 (rank : 246)	NC score	-0.000103 (rank : 303)
Query Neighborhood Hits	248	Target Neighborhood Hits	1066	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

SSH1_MOUSE
θ value	8.99809 (rank : 247)	NC score	0.001898 (rank : 299)
Query Neighborhood Hits	248	Target Neighborhood Hits	107	Shared Neighborhood Hits	4
SwissProt Accessions	Q76I79, Q3TDG3, Q69ZM4, Q811E5	Gene names	Ssh1, Kiaa1298, Ssh1l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (mSSH-1L).

ZCH11_HUMAN
θ value	8.99809 (rank : 248)	NC score	0.013732 (rank : 252)
Query Neighborhood Hits	248	Target Neighborhood Hits	278	Shared Neighborhood Hits	22
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

BASP_HUMAN
θ value	θ > 10 (rank : 249)	NC score	0.060344 (rank : 146)
Query Neighborhood Hits	248	Target Neighborhood Hits	321	Shared Neighborhood Hits	32
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BSN_HUMAN
θ value	θ > 10 (rank : 250)	NC score	0.063358 (rank : 144)
Query Neighborhood Hits	248	Target Neighborhood Hits	1537	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

BSN_MOUSE
θ value	θ > 10 (rank : 251)	NC score	0.064301 (rank : 143)
Query Neighborhood Hits	248	Target Neighborhood Hits	2057	Shared Neighborhood Hits	71
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CPNE1_HUMAN
θ value	θ > 10 (rank : 252)	NC score	0.122907 (rank : 124)
Query Neighborhood Hits	248	Target Neighborhood Hits	70	Shared Neighborhood Hits	54
SwissProt Accessions	Q99829, Q6IBL3, Q9H243, Q9NTZ7	Gene names	CPNE1, CPN1
Domain Architecture
Description	Copine-1 (Copine I).

CPNE1_MOUSE
θ value	θ > 10 (rank : 253)	NC score	0.146484 (rank : 120)
Query Neighborhood Hits	248	Target Neighborhood Hits	83	Shared Neighborhood Hits	59
SwissProt Accessions	Q8C166, Q925K4, Q925K5	Gene names	Cpne1
Domain Architecture
Description	Copine-1 (Copine I).

CPNE2_HUMAN
θ value	θ > 10 (rank : 254)	NC score	0.144980 (rank : 121)
Query Neighborhood Hits	248	Target Neighborhood Hits	75	Shared Neighborhood Hits	54
SwissProt Accessions	Q96FN4, Q68D19, Q86XP9	Gene names	CPNE2
Domain Architecture
Description	Copine-2 (Copine II).

CPNE2_MOUSE
θ value	θ > 10 (rank : 255)	NC score	0.146562 (rank : 119)
Query Neighborhood Hits	248	Target Neighborhood Hits	82	Shared Neighborhood Hits	57
SwissProt Accessions	P59108, Q8K1D7	Gene names	Cpne2
Domain Architecture
Description	Copine-2 (Copine II).

CPNE3_HUMAN
θ value	θ > 10 (rank : 256)	NC score	0.169383 (rank : 109)
Query Neighborhood Hits	248	Target Neighborhood Hits	90	Shared Neighborhood Hits	61
SwissProt Accessions	O75131, Q8IYA1	Gene names	CPNE3, CPN3, KIAA0636
Domain Architecture
Description	Copine-3 (Copine III).

CPNE3_MOUSE
θ value	θ > 10 (rank : 257)	NC score	0.169180 (rank : 110)
Query Neighborhood Hits	248	Target Neighborhood Hits	90	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BT60, Q5CZX9, Q5DU22	Gene names	Cpne3, Kiaa0636
Domain Architecture
Description	Copine-3 (Copine III).

CPNE4_HUMAN
θ value	θ > 10 (rank : 258)	NC score	0.097075 (rank : 135)
Query Neighborhood Hits	248	Target Neighborhood Hits	70	Shared Neighborhood Hits	50
SwissProt Accessions	Q96A23, Q8TEX1	Gene names	CPNE4
Domain Architecture
Description	Copine-4 (Copine IV) (Copine-8).

CPNE4_MOUSE
θ value	θ > 10 (rank : 259)	NC score	0.093547 (rank : 136)
Query Neighborhood Hits	248	Target Neighborhood Hits	67	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BLR2	Gene names	Cpne4
Domain Architecture	No domain graphic available
Description	Copine-4 (Copine IV).

CPNE5_HUMAN
θ value	θ > 10 (rank : 260)	NC score	0.160988 (rank : 113)
Query Neighborhood Hits	248	Target Neighborhood Hits	88	Shared Neighborhood Hits	62
SwissProt Accessions	Q9HCH3	Gene names	CPNE5, KIAA1599
Domain Architecture
Description	Copine-5 (Copine V).

CPNE5_MOUSE
θ value	θ > 10 (rank : 261)	NC score	0.159739 (rank : 114)
Query Neighborhood Hits	248	Target Neighborhood Hits	86	Shared Neighborhood Hits	62
SwissProt Accessions	Q8JZW4	Gene names	Cpne5
Domain Architecture
Description	Copine-5 (Copine V).

CPNE6_HUMAN
θ value	θ > 10 (rank : 262)	NC score	0.108958 (rank : 127)
Query Neighborhood Hits	248	Target Neighborhood Hits	85	Shared Neighborhood Hits	55
SwissProt Accessions	O95741, Q53HA6, Q8WVG1	Gene names	CPNE6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

CPNE6_MOUSE
θ value	θ > 10 (rank : 263)	NC score	0.107634 (rank : 128)
Query Neighborhood Hits	248	Target Neighborhood Hits	87	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Z140	Gene names	Cpne6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

DAB2P_HUMAN
θ value	θ > 10 (rank : 264)	NC score	0.061811 (rank : 145)
Query Neighborhood Hits	248	Target Neighborhood Hits	303	Shared Neighborhood Hits	23
SwissProt Accessions	Q5VWQ8, Q8TDL2, Q96SE1, Q9C0C0	Gene names	DAB2IP, AF9Q34, AIP1, KIAA1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein) (DAB2 interaction protein) (ASK-interacting protein 1).

DAB2P_MOUSE
θ value	θ > 10 (rank : 265)	NC score	0.059282 (rank : 147)
Query Neighborhood Hits	248	Target Neighborhood Hits	284	Shared Neighborhood Hits	21
SwissProt Accessions	Q3UHC7, Q3TPD5, Q3UH44, Q6JTV1, Q80T97	Gene names	Dab2ip, Kiaa1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein).

ITSN2_MOUSE
θ value	θ > 10 (rank : 266)	NC score	0.133303 (rank : 122)
Query Neighborhood Hits	248	Target Neighborhood Hits	1371	Shared Neighborhood Hits	102
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

MARCS_HUMAN
θ value	θ > 10 (rank : 267)	NC score	0.053553 (rank : 155)
Query Neighborhood Hits	248	Target Neighborhood Hits	204	Shared Neighborhood Hits	17
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

MELPH_MOUSE
θ value	θ > 10 (rank : 268)	NC score	0.203460 (rank : 96)
Query Neighborhood Hits	248	Target Neighborhood Hits	112	Shared Neighborhood Hits	16
SwissProt Accessions	Q91V27, Q99N53	Gene names	Mlph, Ln, Slac2a
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Leaden protein) (Synaptotagmin-like protein 2a) (Slac2-a) (Slp homolog lacking C2 domains a).

MYRIP_HUMAN
θ value	θ > 10 (rank : 269)	NC score	0.212546 (rank : 91)
Query Neighborhood Hits	248	Target Neighborhood Hits	269	Shared Neighborhood Hits	39
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

NGAP_HUMAN
θ value	θ > 10 (rank : 270)	NC score	0.050596 (rank : 169)
Query Neighborhood Hits	248	Target Neighborhood Hits	517	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UJF2, O95174, Q5TFU9	Gene names	RASAL2, NGAP
Domain Architecture
Description	Ras GTPase-activating protein nGAP (RAS protein activator-like 1).

NOLC1_HUMAN
θ value	θ > 10 (rank : 271)	NC score	0.051070 (rank : 164)
Query Neighborhood Hits	248	Target Neighborhood Hits	452	Shared Neighborhood Hits	52
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

PA24A_HUMAN
θ value	θ > 10 (rank : 272)	NC score	0.162537 (rank : 112)
Query Neighborhood Hits	248	Target Neighborhood Hits	88	Shared Neighborhood Hits	70
SwissProt Accessions	P47712	Gene names	PLA2G4A, CPLA2, PLA2G4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

PA24A_MOUSE
θ value	θ > 10 (rank : 273)	NC score	0.174594 (rank : 107)
Query Neighborhood Hits	248	Target Neighborhood Hits	100	Shared Neighborhood Hits	69
SwissProt Accessions	P47713	Gene names	Pla2g4a, Cpla2, Pla2g4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

PA24B_HUMAN
θ value	θ > 10 (rank : 274)	NC score	0.165754 (rank : 111)
Query Neighborhood Hits	248	Target Neighborhood Hits	89	Shared Neighborhood Hits	63
SwissProt Accessions	O95712, Q59GF9, Q8TB10, Q9UKV7	Gene names	PLA2G4B
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

PA24B_MOUSE
θ value	θ > 10 (rank : 275)	NC score	0.207353 (rank : 95)
Query Neighborhood Hits	248	Target Neighborhood Hits	102	Shared Neighborhood Hits	68
SwissProt Accessions	Q4QQM1, Q80VV8, Q91W88	Gene names	Pla2g4b
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

PA24E_MOUSE
θ value	θ > 10 (rank : 276)	NC score	0.192822 (rank : 100)
Query Neighborhood Hits	248	Target Neighborhood Hits	95	Shared Neighborhood Hits	72
SwissProt Accessions	Q50L42, Q8BX44	Gene names	Pla2g4e
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

PA24F_HUMAN
θ value	θ > 10 (rank : 277)	NC score	0.110658 (rank : 126)
Query Neighborhood Hits	248	Target Neighborhood Hits	78	Shared Neighborhood Hits	56
SwissProt Accessions	Q68DD2, Q6ZMC8	Gene names	PLA2G4F
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

PA24F_MOUSE
θ value	θ > 10 (rank : 278)	NC score	0.130240 (rank : 123)
Query Neighborhood Hits	248	Target Neighborhood Hits	93	Shared Neighborhood Hits	58
SwissProt Accessions	Q50L41, Q80VQ8, Q80VV9	Gene names	Pla2g4f
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

PDZD8_HUMAN
θ value	θ > 10 (rank : 279)	NC score	0.052308 (rank : 160)
Query Neighborhood Hits	248	Target Neighborhood Hits	185	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

PI4KA_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.050988 (rank : 166)
Query Neighborhood Hits	248	Target Neighborhood Hits	53	Shared Neighborhood Hits	6
SwissProt Accessions	P42356, Q7Z625, Q9UPG2	Gene names	PIK4CA, PIK4
Domain Architecture
Description	Phosphatidylinositol 4-kinase alpha (EC 2.7.1.67) (PI4-kinase alpha) (PtdIns-4-kinase alpha) (PI4K-alpha).

PK3C3_HUMAN
θ value	θ > 10 (rank : 281)	NC score	0.051031 (rank : 165)
Query Neighborhood Hits	248	Target Neighborhood Hits	49	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NEB9, Q15134	Gene names	PIK3C3
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC 2.7.1.137) (PtdIns-3-kinase type 3) (PI3-kinase type 3) (PI3K type 3) (Phosphoinositide-3-kinase class 3) (Phosphatidylinositol 3-kinase p100 subunit).

PK3C3_MOUSE
θ value	θ > 10 (rank : 282)	NC score	0.050854 (rank : 167)
Query Neighborhood Hits	248	Target Neighborhood Hits	49	Shared Neighborhood Hits	7
SwissProt Accessions	Q6PF93, Q8R3S8	Gene names	Pik3c3
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC 2.7.1.137) (PtdIns-3-kinase type 3) (PI3-kinase type 3) (PI3K type 3) (Phosphoinositide-3-kinase class 3).

PK3CA_HUMAN
θ value	θ > 10 (rank : 283)	NC score	0.056642 (rank : 151)
Query Neighborhood Hits	248	Target Neighborhood Hits	45	Shared Neighborhood Hits	7
SwissProt Accessions	P42336, Q99762	Gene names	PIK3CA
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).

PK3CA_MOUSE
θ value	θ > 10 (rank : 284)	NC score	0.056710 (rank : 150)
Query Neighborhood Hits	248	Target Neighborhood Hits	48	Shared Neighborhood Hits	7
SwissProt Accessions	P42337	Gene names	Pik3ca
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).

PK3CB_HUMAN
θ value	θ > 10 (rank : 285)	NC score	0.053474 (rank : 157)
Query Neighborhood Hits	248	Target Neighborhood Hits	43	Shared Neighborhood Hits	6
SwissProt Accessions	P42338	Gene names	PIK3CB
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).

PK3CB_MOUSE
θ value	θ > 10 (rank : 286)	NC score	0.053497 (rank : 156)
Query Neighborhood Hits	248	Target Neighborhood Hits	49	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BTI9	Gene names	Pik3cb
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).

PK3CD_HUMAN
θ value	θ > 10 (rank : 287)	NC score	0.054056 (rank : 153)
Query Neighborhood Hits	248	Target Neighborhood Hits	40	Shared Neighborhood Hits	7
SwissProt Accessions	O00329, O15445	Gene names	PIK3CD
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit delta) (PtdIns-3- kinase p110) (PI3K) (p110delta).

PK3CD_MOUSE
θ value	θ > 10 (rank : 288)	NC score	0.053948 (rank : 154)
Query Neighborhood Hits	248	Target Neighborhood Hits	42	Shared Neighborhood Hits	6
SwissProt Accessions	O35904	Gene names	Pik3cd
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit delta) (PtdIns-3- kinase p110) (PI3K) (p110delta).

PK3CG_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.058302 (rank : 148)
Query Neighborhood Hits	248	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	P48736, Q8IV23, Q9BZC8	Gene names	PIK3CG
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

PK3CG_MOUSE
θ value	θ > 10 (rank : 290)	NC score	0.058131 (rank : 149)
Query Neighborhood Hits	248	Target Neighborhood Hits	43	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JHG7	Gene names	Pik3cg, Pi3kg1
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

PLCD1_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.114400 (rank : 125)
Query Neighborhood Hits	248	Target Neighborhood Hits	93	Shared Neighborhood Hits	51
SwissProt Accessions	P51178	Gene names	PLCD1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

PLCD1_MOUSE
θ value	θ > 10 (rank : 292)	NC score	0.076665 (rank : 138)
Query Neighborhood Hits	248	Target Neighborhood Hits	106	Shared Neighborhood Hits	48
SwissProt Accessions	Q8R3B1	Gene names	Plcd1, Plcd
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

RASA1_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.067831 (rank : 141)
Query Neighborhood Hits	248	Target Neighborhood Hits	258	Shared Neighborhood Hits	25
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

RIMS3_HUMAN
θ value	θ > 10 (rank : 294)	NC score	0.391785 (rank : 69)
Query Neighborhood Hits	248	Target Neighborhood Hits	66	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UJD0, Q92511	Gene names	RIMS3, KIAA0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

SMUF1_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.104586 (rank : 130)
Query Neighborhood Hits	248	Target Neighborhood Hits	135	Shared Neighborhood Hits	54
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

SMUF1_MOUSE
θ value	θ > 10 (rank : 296)	NC score	0.103425 (rank : 132)
Query Neighborhood Hits	248	Target Neighborhood Hits	142	Shared Neighborhood Hits	54
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

SMUF2_HUMAN
θ value	θ > 10 (rank : 297)	NC score	0.103231 (rank : 133)
Query Neighborhood Hits	248	Target Neighborhood Hits	142	Shared Neighborhood Hits	55
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

SRRM1_MOUSE
θ value	θ > 10 (rank : 298)	NC score	0.052483 (rank : 158)
Query Neighborhood Hits	248	Target Neighborhood Hits	966	Shared Neighborhood Hits	61
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SYGP1_HUMAN
θ value	θ > 10 (rank : 299)	NC score	0.050646 (rank : 168)
Query Neighborhood Hits	248	Target Neighborhood Hits	589	Shared Neighborhood Hits	29
SwissProt Accessions	Q96PV0, Q8TCS2, Q9UGE2	Gene names	SYNGAP1, KIAA1938
Domain Architecture
Description	Ras GTPase-activating protein SynGAP (Synaptic Ras-GTPase-activating protein 1) (Synaptic Ras-GAP 1) (Neuronal RasGAP).

SYT8_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.077988 (rank : 137)
Query Neighborhood Hits	248	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NBV8, Q9NSV9	Gene names	SYT8
Domain Architecture	No domain graphic available
Description	Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII).

TAC2N_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.282267 (rank : 85)
Query Neighborhood Hits	248	Target Neighborhood Hits	47	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N9U0	Gene names	MTAC2D1, C14orf47
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

TAC2N_MOUSE
θ value	θ > 10 (rank : 302)	NC score	0.280953 (rank : 86)
Query Neighborhood Hits	248	Target Neighborhood Hits	43	Shared Neighborhood Hits	36
SwissProt Accessions	Q91XT6, Q9D4A0	Gene names	Mtac2d1
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

WWC1_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.072309 (rank : 139)
Query Neighborhood Hits	248	Target Neighborhood Hits	290	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

WWC1_MOUSE
θ value	θ > 10 (rank : 304)	NC score	0.101420 (rank : 134)
Query Neighborhood Hits	248	Target Neighborhood Hits	290	Shared Neighborhood Hits	36
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

WWP1_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.051559 (rank : 163)
Query Neighborhood Hits	248	Target Neighborhood Hits	262	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

Hits sorted by NC score

SYTL2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	248	Target Neighborhood Hits	248	Shared Neighborhood Hits	248
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

SYTL2_MOUSE
NC score	0.976074 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	248	Target Neighborhood Hits	253	Shared Neighborhood Hits	121
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

SYTL1_HUMAN
NC score	0.932837 (rank : 3)	θ value	4.50487e-84 (rank : 3)
Query Neighborhood Hits	248	Target Neighborhood Hits	227	Shared Neighborhood Hits	108
SwissProt Accessions	Q8IYJ3, Q96BB6, Q96GU6, Q96S89, Q96SI0	Gene names	SYTL1, SLP1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1) (SB146).

SYTL4_HUMAN
NC score	0.921384 (rank : 4)	θ value	5.51964e-74 (rank : 6)
Query Neighborhood Hits	248	Target Neighborhood Hits	138	Shared Neighborhood Hits	97
SwissProt Accessions	Q96C24, Q5H9J3, Q5JPG8, Q8N9P4, Q9H4R0, Q9H4R1	Gene names	SYTL4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

SYTL4_MOUSE
NC score	0.919358 (rank : 5)	θ value	1.11217e-74 (rank : 5)
Query Neighborhood Hits	248	Target Neighborhood Hits	137	Shared Neighborhood Hits	97
SwissProt Accessions	Q9R0Q1, Q8R321, Q9R0Q0	Gene names	Sytl4, Slp4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

SYTL1_MOUSE
NC score	0.917972 (rank : 6)	θ value	3.22841e-82 (rank : 4)
Query Neighborhood Hits	248	Target Neighborhood Hits	314	Shared Neighborhood Hits	107
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

SYTL5_MOUSE
NC score	0.913361 (rank : 7)	θ value	5.7252e-63 (rank : 8)
Query Neighborhood Hits	248	Target Neighborhood Hits	154	Shared Neighborhood Hits	100
SwissProt Accessions	Q80T23, Q812E5	Gene names	Sytl5, Slp5
Domain Architecture
Description	Synaptotagmin-like protein 5.

SYTL5_HUMAN
NC score	0.910097 (rank : 8)	θ value	8.24801e-70 (rank : 7)
Query Neighborhood Hits	248	Target Neighborhood Hits	237	Shared Neighborhood Hits	114
SwissProt Accessions	Q8TDW5	Gene names	SYTL5, SLP5
Domain Architecture
Description	Synaptotagmin-like protein 5.

SYTL3_MOUSE
NC score	0.901486 (rank : 9)	θ value	4.25575e-50 (rank : 9)
Query Neighborhood Hits	248	Target Neighborhood Hits	110	Shared Neighborhood Hits	85
SwissProt Accessions	Q99N48, Q8C506, Q99N47, Q99N49, Q99N54, Q99N79	Gene names	Sytl3, Slp3
Domain Architecture
Description	Synaptotagmin-like protein 3 (Exophilin-6).

DOC2B_MOUSE
NC score	0.799978 (rank : 10)	θ value	5.99374e-20 (rank : 17)
Query Neighborhood Hits	248	Target Neighborhood Hits	169	Shared Neighborhood Hits	102
SwissProt Accessions	P70169, Q6NXK3	Gene names	Doc2b
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

DOC2B_HUMAN
NC score	0.798769 (rank : 11)	θ value	5.07402e-19 (rank : 19)
Query Neighborhood Hits	248	Target Neighborhood Hits	150	Shared Neighborhood Hits	102
SwissProt Accessions	Q14184	Gene names	DOC2B
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

SYT3_HUMAN
NC score	0.798326 (rank : 12)	θ value	6.84181e-24 (rank : 10)
Query Neighborhood Hits	248	Target Neighborhood Hits	145	Shared Neighborhood Hits	103
SwissProt Accessions	Q9BQG1, Q8N5Z1, Q8N640	Gene names	SYT3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

SYT3_MOUSE
NC score	0.798023 (rank : 13)	θ value	1.29031e-22 (rank : 11)
Query Neighborhood Hits	248	Target Neighborhood Hits	147	Shared Neighborhood Hits	104
SwissProt Accessions	O35681, P97791, Q80WV1	Gene names	Syt3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

DOC2A_MOUSE
NC score	0.797529 (rank : 14)	θ value	1.16975e-15 (rank : 32)
Query Neighborhood Hits	248	Target Neighborhood Hits	140	Shared Neighborhood Hits	99
SwissProt Accessions	Q7TNF0	Gene names	Doc2a
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha).

DOC2A_HUMAN
NC score	0.796487 (rank : 15)	θ value	6.85773e-16 (rank : 31)
Query Neighborhood Hits	248	Target Neighborhood Hits	144	Shared Neighborhood Hits	100
SwissProt Accessions	Q14183, Q6P4G4, Q7Z5G0, Q8IVX0	Gene names	DOC2A
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha) (Doc2).

SYT2_MOUSE
NC score	0.792501 (rank : 16)	θ value	3.51386e-20 (rank : 15)
Query Neighborhood Hits	248	Target Neighborhood Hits	143	Shared Neighborhood Hits	103
SwissProt Accessions	P46097, Q8R0E1	Gene names	Syt2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT2_HUMAN
NC score	0.792480 (rank : 17)	θ value	4.58923e-20 (rank : 16)
Query Neighborhood Hits	248	Target Neighborhood Hits	142	Shared Neighborhood Hits	103
SwissProt Accessions	Q8N9I0, Q496K5, Q8NBE5	Gene names	SYT2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT5_MOUSE
NC score	0.789779 (rank : 18)	θ value	4.44505e-15 (rank : 35)
Query Neighborhood Hits	248	Target Neighborhood Hits	140	Shared Neighborhood Hits	103
SwissProt Accessions	Q9R0N5	Gene names	Syt5, Syt9
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV) (Synaptotagmin IX).

SYT5_HUMAN
NC score	0.789423 (rank : 19)	θ value	2.60593e-15 (rank : 34)
Query Neighborhood Hits	248	Target Neighborhood Hits	138	Shared Neighborhood Hits	103
SwissProt Accessions	O00445, Q86X72	Gene names	SYT5
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV).

SYT7_MOUSE
NC score	0.786219 (rank : 20)	θ value	9.90251e-15 (rank : 36)
Query Neighborhood Hits	248	Target Neighborhood Hits	137	Shared Neighborhood Hits	103
SwissProt Accessions	Q9R0N7	Gene names	Syt7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

SYT7_HUMAN
NC score	0.785789 (rank : 21)	θ value	1.09485e-13 (rank : 37)
Query Neighborhood Hits	248	Target Neighborhood Hits	137	Shared Neighborhood Hits	103
SwissProt Accessions	O43581	Gene names	SYT7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

SYT6_MOUSE
NC score	0.784711 (rank : 22)	θ value	2.87452e-22 (rank : 12)
Query Neighborhood Hits	248	Target Neighborhood Hits	132	Shared Neighborhood Hits	100
SwissProt Accessions	Q9R0N8	Gene names	Syt6
Domain Architecture
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

SYT1_HUMAN
NC score	0.784027 (rank : 23)	θ value	2.7842e-17 (rank : 24)
Query Neighborhood Hits	248	Target Neighborhood Hits	150	Shared Neighborhood Hits	103
SwissProt Accessions	P21579	Gene names	SYT1, SYT
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT1_MOUSE
NC score	0.784006 (rank : 24)	θ value	2.7842e-17 (rank : 25)
Query Neighborhood Hits	248	Target Neighborhood Hits	150	Shared Neighborhood Hits	103
SwissProt Accessions	P46096	Gene names	Syt1
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT6_HUMAN
NC score	0.783832 (rank : 25)	θ value	8.36355e-22 (rank : 13)
Query Neighborhood Hits	248	Target Neighborhood Hits	138	Shared Neighborhood Hits	100
SwissProt Accessions	Q5T7P8	Gene names	SYT6
Domain Architecture	No domain graphic available
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

SYT11_MOUSE
NC score	0.779555 (rank : 26)	θ value	1.92812e-18 (rank : 23)
Query Neighborhood Hits	248	Target Neighborhood Hits	116	Shared Neighborhood Hits	99
SwissProt Accessions	Q9R0N3	Gene names	Syt11
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

SYT10_HUMAN
NC score	0.779442 (rank : 27)	θ value	6.62687e-19 (rank : 20)
Query Neighborhood Hits	248	Target Neighborhood Hits	134	Shared Neighborhood Hits	100
SwissProt Accessions	Q6XYQ8	Gene names	SYT10
Domain Architecture	No domain graphic available
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

SYT11_HUMAN
NC score	0.779014 (rank : 28)	θ value	1.13037e-18 (rank : 22)
Query Neighborhood Hits	248	Target Neighborhood Hits	113	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BT88, Q14998, Q68CT5, Q8IXU3, Q96SU2	Gene names	SYT11, KIAA0080
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

RP3A_HUMAN
NC score	0.778096 (rank : 29)	θ value	1.74391e-19 (rank : 18)
Query Neighborhood Hits	248	Target Neighborhood Hits	305	Shared Neighborhood Hits	115
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SYT10_MOUSE
NC score	0.776452 (rank : 30)	θ value	6.62687e-19 (rank : 21)
Query Neighborhood Hits	248	Target Neighborhood Hits	133	Shared Neighborhood Hits	101
SwissProt Accessions	Q9R0N4	Gene names	Syt10
Domain Architecture
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

SYT9_HUMAN
NC score	0.776240 (rank : 31)	θ value	4.74913e-17 (rank : 26)
Query Neighborhood Hits	248	Target Neighborhood Hits	144	Shared Neighborhood Hits	102
SwissProt Accessions	Q86SS6	Gene names	SYT9
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX).

SYT9_MOUSE
NC score	0.774482 (rank : 32)	θ value	4.74913e-17 (rank : 27)
Query Neighborhood Hits	248	Target Neighborhood Hits	148	Shared Neighborhood Hits	102
SwissProt Accessions	Q9R0N9, Q8C280	Gene names	Syt9, Syt5
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX) (Synaptotagmin V).

SYT4_HUMAN
NC score	0.774057 (rank : 33)	θ value	2.35696e-16 (rank : 29)
Query Neighborhood Hits	248	Target Neighborhood Hits	121	Shared Neighborhood Hits	98
SwissProt Accessions	Q9H2B2, Q9P2K4	Gene names	SYT4, KIAA1342
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

RP3A_MOUSE
NC score	0.773043 (rank : 34)	θ value	1.2077e-20 (rank : 14)
Query Neighborhood Hits	248	Target Neighborhood Hits	510	Shared Neighborhood Hits	121
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SYT4_MOUSE
NC score	0.772073 (rank : 35)	θ value	5.25075e-16 (rank : 30)
Query Neighborhood Hits	248	Target Neighborhood Hits	123	Shared Neighborhood Hits	96
SwissProt Accessions	P40749, Q3UFC1, Q8BGH3, Q8BRL6	Gene names	Syt4, Syt3
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

DOC2G_MOUSE
NC score	0.768432 (rank : 36)	θ value	1.133e-10 (rank : 42)
Query Neighborhood Hits	248	Target Neighborhood Hits	125	Shared Neighborhood Hits	96
SwissProt Accessions	Q9ESN1, Q6P8R8	Gene names	Doc2g
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein gamma (Doc2-gamma).

SYT12_MOUSE
NC score	0.750682 (rank : 37)	θ value	1.133e-10 (rank : 43)
Query Neighborhood Hits	248	Target Neighborhood Hits	102	Shared Neighborhood Hits	88
SwissProt Accessions	Q920N7	Gene names	Syt12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

SYT12_HUMAN
NC score	0.746358 (rank : 38)	θ value	9.59137e-10 (rank : 47)
Query Neighborhood Hits	248	Target Neighborhood Hits	100	Shared Neighborhood Hits	86
SwissProt Accessions	Q8IV01	Gene names	SYT12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

SYT15_HUMAN
NC score	0.742690 (rank : 39)	θ value	3.89403e-11 (rank : 38)
Query Neighborhood Hits	248	Target Neighborhood Hits	112	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BQS2, Q7Z439, Q7Z440	Gene names	SYT15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV) (Chr10Syt).

SYT8_MOUSE
NC score	0.733168 (rank : 40)	θ value	5.81887e-07 (rank : 57)
Query Neighborhood Hits	248	Target Neighborhood Hits	94	Shared Neighborhood Hits	83
SwissProt Accessions	Q9R0N6, Q64366, Q8C6E7	Gene names	Syt8
Domain Architecture
Description	Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII).

SYT15_MOUSE
NC score	0.703355 (rank : 41)	θ value	4.0297e-08 (rank : 54)
Query Neighborhood Hits	248	Target Neighborhood Hits	100	Shared Neighborhood Hits	86
SwissProt Accessions	Q8C6N3, Q7TN81, Q7TN82, Q8C999	Gene names	Syt15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV).

FA62A_HUMAN
NC score	0.633257 (rank : 42)	θ value	8.11959e-09 (rank : 52)
Query Neighborhood Hits	248	Target Neighborhood Hits	168	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

FA62A_MOUSE
NC score	0.632950 (rank : 43)	θ value	1.80886e-08 (rank : 53)
Query Neighborhood Hits	248	Target Neighborhood Hits	155	Shared Neighborhood Hits	99
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

SYT13_HUMAN
NC score	0.603536 (rank : 44)	θ value	0.0193708 (rank : 88)
Query Neighborhood Hits	248	Target Neighborhood Hits	76	Shared Neighborhood Hits	66
SwissProt Accessions	Q7L8C5, Q9BQS3, Q9H041, Q9P2C0	Gene names	SYT13, KIAA1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

SYT13_MOUSE
NC score	0.595681 (rank : 45)	θ value	0.0193708 (rank : 89)
Query Neighborhood Hits	248	Target Neighborhood Hits	69	Shared Neighborhood Hits	66
SwissProt Accessions	Q9EQT6, Q6ZPR2, Q8BRK6	Gene names	Syt13, Kiaa1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

SYT14_MOUSE
NC score	0.581459 (rank : 46)	θ value	0.00509761 (rank : 79)
Query Neighborhood Hits	248	Target Neighborhood Hits	82	Shared Neighborhood Hits	62
SwissProt Accessions	Q7TN84	Gene names	Syt14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

SYT14_HUMAN
NC score	0.579287 (rank : 47)	θ value	0.00665767 (rank : 81)
Query Neighborhood Hits	248	Target Neighborhood Hits	81	Shared Neighborhood Hits	60
SwissProt Accessions	Q8NB59, Q5THX7, Q707N3, Q707N4, Q707N5, Q707N6, Q707N7	Gene names	SYT14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

RIMS1_HUMAN
NC score	0.566108 (rank : 48)	θ value	9.59137e-10 (rank : 46)
Query Neighborhood Hits	248	Target Neighborhood Hits	437	Shared Neighborhood Hits	110
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

RASL2_HUMAN
NC score	0.565232 (rank : 49)	θ value	8.40245e-06 (rank : 64)
Query Neighborhood Hits	248	Target Neighborhood Hits	161	Shared Neighborhood Hits	96
SwissProt Accessions	O43374, O60286, Q86UW3, Q96QU0	Gene names	RASA4, CAPRI, GAPL, KIAA0538
Domain Architecture
Description	Ras GTPase-activating protein 4 (RasGAP-activating-like protein 2) (Calcium-promoted Ras inactivator).

RIMS2_HUMAN
NC score	0.550825 (rank : 50)	θ value	5.81887e-07 (rank : 55)
Query Neighborhood Hits	248	Target Neighborhood Hits	342	Shared Neighborhood Hits	108
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
NC score	0.544893 (rank : 51)	θ value	5.81887e-07 (rank : 56)
Query Neighborhood Hits	248	Target Neighborhood Hits	376	Shared Neighborhood Hits	110
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

PCLO_HUMAN
NC score	0.519923 (rank : 52)	θ value	1.80466e-16 (rank : 28)
Query Neighborhood Hits	248	Target Neighborhood Hits	2046	Shared Neighborhood Hits	168
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

RIMS4_MOUSE
NC score	0.499791 (rank : 53)	θ value	1.69304e-06 (rank : 59)
Query Neighborhood Hits	248	Target Neighborhood Hits	76	Shared Neighborhood Hits	71
SwissProt Accessions	P60191	Gene names	Rims4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

RIMS4_HUMAN
NC score	0.496240 (rank : 54)	θ value	2.21117e-06 (rank : 60)
Query Neighborhood Hits	248	Target Neighborhood Hits	76	Shared Neighborhood Hits	71
SwissProt Accessions	Q9H426, Q5JWT7	Gene names	RIMS4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

PCLO_MOUSE
NC score	0.488871 (rank : 55)	θ value	1.52774e-15 (rank : 33)
Query Neighborhood Hits	248	Target Neighborhood Hits	2275	Shared Neighborhood Hits	172
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

P3C2B_HUMAN
NC score	0.483614 (rank : 56)	θ value	1.29631e-06 (rank : 58)
Query Neighborhood Hits	248	Target Neighborhood Hits	148	Shared Neighborhood Hits	83
SwissProt Accessions	O00750, O95666, Q5SW99	Gene names	PIK3C2B
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-beta) (PtdIns-3-kinase C2 beta) (PI3K-C2beta) (C2-PI3K).

RASL1_HUMAN
NC score	0.462660 (rank : 57)	θ value	0.00228821 (rank : 74)
Query Neighborhood Hits	248	Target Neighborhood Hits	142	Shared Neighborhood Hits	85
SwissProt Accessions	O95294, Q52M03, Q96CC7	Gene names	RASAL1, RASAL
Domain Architecture
Description	RasGAP-activating-like protein 1.

P3C2A_HUMAN
NC score	0.457690 (rank : 58)	θ value	2.52405e-10 (rank : 45)
Query Neighborhood Hits	248	Target Neighborhood Hits	188	Shared Neighborhood Hits	78
SwissProt Accessions	O00443	Gene names	PIK3C2A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha).

P3C2A_MOUSE
NC score	0.453863 (rank : 59)	θ value	2.13673e-09 (rank : 51)
Query Neighborhood Hits	248	Target Neighborhood Hits	181	Shared Neighborhood Hits	76
SwissProt Accessions	Q61194, Q61182	Gene names	Pik3c2a, Cpk
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).

RASL1_MOUSE
NC score	0.452713 (rank : 60)	θ value	0.000786445 (rank : 73)
Query Neighborhood Hits	248	Target Neighborhood Hits	148	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Z268	Gene names	Rasal1, Rasal
Domain Architecture
Description	RasGAP-activating-like protein 1.

RASA2_MOUSE
NC score	0.445354 (rank : 61)	θ value	2.44474e-05 (rank : 67)
Query Neighborhood Hits	248	Target Neighborhood Hits	159	Shared Neighborhood Hits	85
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

UN13D_HUMAN
NC score	0.442741 (rank : 62)	θ value	2.36792 (rank : 165)
Query Neighborhood Hits	248	Target Neighborhood Hits	117	Shared Neighborhood Hits	87
SwissProt Accessions	Q70J99, Q9H7K5	Gene names	UNC13D
Domain Architecture	No domain graphic available
Description	Unc-13 homolog D (Munc13-4).

RASA2_HUMAN
NC score	0.439479 (rank : 63)	θ value	8.40245e-06 (rank : 63)
Query Neighborhood Hits	248	Target Neighborhood Hits	157	Shared Neighborhood Hits	85
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

K0528_HUMAN
NC score	0.424150 (rank : 64)	θ value	0.00390308 (rank : 76)
Query Neighborhood Hits	248	Target Neighborhood Hits	96	Shared Neighborhood Hits	77
SwissProt Accessions	Q86YS7, O60280, Q7Z619, Q86SU3	Gene names	KIAA0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

K0528_MOUSE
NC score	0.423688 (rank : 65)	θ value	0.00390308 (rank : 77)
Query Neighborhood Hits	248	Target Neighborhood Hits	102	Shared Neighborhood Hits	78
SwissProt Accessions	Q7TPS5, Q3TQY6, Q6A052, Q80VA1, Q8C0U3, Q8CID5, Q9CS85	Gene names	Kiaa0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

RASA3_HUMAN
NC score	0.419648 (rank : 66)	θ value	1.63604e-09 (rank : 50)
Query Neighborhood Hits	248	Target Neighborhood Hits	166	Shared Neighborhood Hits	82
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

BAIP3_HUMAN
NC score	0.410074 (rank : 67)	θ value	4.03905 (rank : 181)
Query Neighborhood Hits	248	Target Neighborhood Hits	108	Shared Neighborhood Hits	82
SwissProt Accessions	O94812, O94839, Q2M226, Q658J2, Q76N05, Q96RZ3, Q9UJK1	Gene names	BAIAP3, KIAA0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

BAIP3_MOUSE
NC score	0.408301 (rank : 68)	θ value	4.03905 (rank : 182)
Query Neighborhood Hits	248	Target Neighborhood Hits	112	Shared Neighborhood Hits	86
SwissProt Accessions	Q80TT2, Q6RUT4	Gene names	Baiap3, Gm937, Kiaa0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

RIMS3_HUMAN
NC score	0.391785 (rank : 69)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	248	Target Neighborhood Hits	66	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UJD0, Q92511	Gene names	RIMS3, KIAA0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

RIMS3_MOUSE
NC score	0.389863 (rank : 70)	θ value	8.99809 (rank : 244)
Query Neighborhood Hits	248	Target Neighborhood Hits	67	Shared Neighborhood Hits	65
SwissProt Accessions	Q80U57	Gene names	Rims3, Kiaa0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

RFIP2_HUMAN
NC score	0.373430 (rank : 71)	θ value	6.43352e-06 (rank : 62)
Query Neighborhood Hits	248	Target Neighborhood Hits	97	Shared Neighborhood Hits	75
SwissProt Accessions	Q7L804, Q9Y2F0	Gene names	RAB11FIP2, KIAA0941
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 2 (Rab11-FIP2) (NRip11).

DYSF_HUMAN
NC score	0.364827 (rank : 72)	θ value	0.00020696 (rank : 71)
Query Neighborhood Hits	248	Target Neighborhood Hits	170	Shared Neighborhood Hits	100
SwissProt Accessions	O75923, O75696, Q9UEN7	Gene names	DYSF, FER1L1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

RASA3_MOUSE
NC score	0.362847 (rank : 73)	θ value	3.77169e-06 (rank : 61)
Query Neighborhood Hits	248	Target Neighborhood Hits	144	Shared Neighborhood Hits	74
SwissProt Accessions	Q60790	Gene names	Rasa3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) (GapIII).

DYSF_MOUSE
NC score	0.359101 (rank : 74)	θ value	0.00509761 (rank : 78)
Query Neighborhood Hits	248	Target Neighborhood Hits	162	Shared Neighborhood Hits	98
SwissProt Accessions	Q9ESD7, Q9QXC0	Gene names	Dysf, Fer1l1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

MYOF_HUMAN
NC score	0.353068 (rank : 75)	θ value	0.00869519 (rank : 82)
Query Neighborhood Hits	248	Target Neighborhood Hits	147	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NZM1, Q9HBU3, Q9NZM0, Q9ULL3, Q9Y4U4	Gene names	FER1L3, KIAA1207, MYOF
Domain Architecture
Description	Myoferlin (Fer-1-like protein 3).

NED4L_HUMAN
NC score	0.310546 (rank : 76)	θ value	4.1701e-05 (rank : 68)
Query Neighborhood Hits	248	Target Neighborhood Hits	238	Shared Neighborhood Hits	97
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NED4L_MOUSE
NC score	0.306576 (rank : 77)	θ value	4.1701e-05 (rank : 69)
Query Neighborhood Hits	248	Target Neighborhood Hits	231	Shared Neighborhood Hits	95
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

OTOF_HUMAN
NC score	0.306229 (rank : 78)	θ value	0.00869519 (rank : 83)
Query Neighborhood Hits	248	Target Neighborhood Hits	168	Shared Neighborhood Hits	79
SwissProt Accessions	Q9HC10, Q9HC08, Q9HC09, Q9Y650	Gene names	OTOF, FER1L2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

OTOF_MOUSE
NC score	0.301763 (rank : 79)	θ value	0.0148317 (rank : 86)
Query Neighborhood Hits	248	Target Neighborhood Hits	196	Shared Neighborhood Hits	85
SwissProt Accessions	Q9ESF1, Q9ESF2	Gene names	Otof, Fer1l2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

UN13A_HUMAN
NC score	0.298807 (rank : 80)	θ value	0.0113563 (rank : 85)
Query Neighborhood Hits	248	Target Neighborhood Hits	285	Shared Neighborhood Hits	93
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

PA24D_MOUSE
NC score	0.297996 (rank : 81)	θ value	0.0148317 (rank : 87)
Query Neighborhood Hits	248	Target Neighborhood Hits	100	Shared Neighborhood Hits	79
SwissProt Accessions	Q50L43, Q3TJC5	Gene names	Pla2g4d
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

UN13B_MOUSE
NC score	0.295820 (rank : 82)	θ value	0.0563607 (rank : 93)
Query Neighborhood Hits	248	Target Neighborhood Hits	210	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

UN13B_HUMAN
NC score	0.291828 (rank : 83)	θ value	0.0961366 (rank : 95)
Query Neighborhood Hits	248	Target Neighborhood Hits	217	Shared Neighborhood Hits	88
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

NEDD4_HUMAN
NC score	0.289886 (rank : 84)	θ value	1.87187e-05 (rank : 66)
Query Neighborhood Hits	248	Target Neighborhood Hits	214	Shared Neighborhood Hits	95
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

TAC2N_HUMAN
NC score	0.282267 (rank : 85)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	248	Target Neighborhood Hits	47	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N9U0	Gene names	MTAC2D1, C14orf47
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

TAC2N_MOUSE
NC score	0.280953 (rank : 86)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	248	Target Neighborhood Hits	43	Shared Neighborhood Hits	36
SwissProt Accessions	Q91XT6, Q9D4A0	Gene names	Mtac2d1
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

NEDD4_MOUSE
NC score	0.276959 (rank : 87)	θ value	7.1131e-05 (rank : 70)
Query Neighborhood Hits	248	Target Neighborhood Hits	212	Shared Neighborhood Hits	95
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

PA24D_HUMAN
NC score	0.260514 (rank : 88)	θ value	0.00298849 (rank : 75)
Query Neighborhood Hits	248	Target Neighborhood Hits	97	Shared Neighborhood Hits	74
SwissProt Accessions	Q86XP0, Q8N176	Gene names	PLA2G4D
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

MYRIP_MOUSE
NC score	0.220493 (rank : 89)	θ value	1.81305 (rank : 151)
Query Neighborhood Hits	248	Target Neighborhood Hits	207	Shared Neighborhood Hits	41
SwissProt Accessions	Q8K3I4, Q8CFC0, Q8K4H5	Gene names	Myrip, Slac2c
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

RGS3_HUMAN
NC score	0.214851 (rank : 90)	θ value	0.0330416 (rank : 91)
Query Neighborhood Hits	248	Target Neighborhood Hits	1375	Shared Neighborhood Hits	121
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

MYRIP_HUMAN
NC score	0.212546 (rank : 91)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	248	Target Neighborhood Hits	269	Shared Neighborhood Hits	39
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

KPCG_HUMAN
NC score	0.210092 (rank : 92)	θ value	5.08577e-11 (rank : 39)
Query Neighborhood Hits	248	Target Neighborhood Hits	1126	Shared Neighborhood Hits	110
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

KPCG_MOUSE
NC score	0.209795 (rank : 93)	θ value	6.64225e-11 (rank : 41)
Query Neighborhood Hits	248	Target Neighborhood Hits	1123	Shared Neighborhood Hits	109
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

MELPH_HUMAN
NC score	0.209376 (rank : 94)	θ value	5.27518 (rank : 208)
Query Neighborhood Hits	248	Target Neighborhood Hits	145	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BV36, Q9HA71	Gene names	MLPH, SLAC2A
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Synaptotagmin-like protein 2a) (Slp homolog lacking C2 domains a).

PA24B_MOUSE
NC score	0.207353 (rank : 95)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	248	Target Neighborhood Hits	102	Shared Neighborhood Hits	68
SwissProt Accessions	Q4QQM1, Q80VV8, Q91W88	Gene names	Pla2g4b
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

MELPH_MOUSE
NC score	0.203460 (rank : 96)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	248	Target Neighborhood Hits	112	Shared Neighborhood Hits	16
SwissProt Accessions	Q91V27, Q99N53	Gene names	Mlph, Ln, Slac2a
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Leaden protein) (Synaptotagmin-like protein 2a) (Slac2-a) (Slp homolog lacking C2 domains a).

P3C2G_MOUSE
NC score	0.198599 (rank : 97)	θ value	0.00665767 (rank : 80)
Query Neighborhood Hits	248	Target Neighborhood Hits	113	Shared Neighborhood Hits	64
SwissProt Accessions	O70167, O70168	Gene names	Pik3c2g
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).

KPCA_HUMAN
NC score	0.195759 (rank : 98)	θ value	6.64225e-11 (rank : 40)
Query Neighborhood Hits	248	Target Neighborhood Hits	1070	Shared Neighborhood Hits	109
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KPCB_MOUSE
NC score	0.194709 (rank : 99)	θ value	1.63604e-09 (rank : 49)
Query Neighborhood Hits	248	Target Neighborhood Hits	1117	Shared Neighborhood Hits	107
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

PA24E_MOUSE
NC score	0.192822 (rank : 100)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	248	Target Neighborhood Hits	95	Shared Neighborhood Hits	72
SwissProt Accessions	Q50L42, Q8BX44	Gene names	Pla2g4e
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

KPCA_MOUSE
NC score	0.192677 (rank : 101)	θ value	2.52405e-10 (rank : 44)
Query Neighborhood Hits	248	Target Neighborhood Hits	1067	Shared Neighborhood Hits	109
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KPCB_HUMAN
NC score	0.192530 (rank : 102)	θ value	1.25267e-09 (rank : 48)
Query Neighborhood Hits	248	Target Neighborhood Hits	1121	Shared Neighborhood Hits	108
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

RFIP1_MOUSE
NC score	0.188061 (rank : 103)	θ value	0.0563607 (rank : 92)
Query Neighborhood Hits	248	Target Neighborhood Hits	152	Shared Neighborhood Hits	50
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

SLC2B_HUMAN
NC score	0.185244 (rank : 104)	θ value	0.0113563 (rank : 84)
Query Neighborhood Hits	248	Target Neighborhood Hits	214	Shared Neighborhood Hits	34
SwissProt Accessions	Q8NEV8, Q9Y4D6	Gene names	EXPH5, KIAA0624, SLAC2B
Domain Architecture	No domain graphic available
Description	Slp homolog lacking C2 domains b (Exophilin-5).

RFIP1_HUMAN
NC score	0.181948 (rank : 105)	θ value	0.0961366 (rank : 94)
Query Neighborhood Hits	248	Target Neighborhood Hits	236	Shared Neighborhood Hits	64
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

P3C2G_HUMAN
NC score	0.180253 (rank : 106)	θ value	0.000602161 (rank : 72)
Query Neighborhood Hits	248	Target Neighborhood Hits	92	Shared Neighborhood Hits	47
SwissProt Accessions	O75747	Gene names	PIK3C2G
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).

PA24A_MOUSE
NC score	0.174594 (rank : 107)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	248	Target Neighborhood Hits	100	Shared Neighborhood Hits	69
SwissProt Accessions	P47713	Gene names	Pla2g4a, Cpla2, Pla2g4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

PA24E_HUMAN
NC score	0.173544 (rank : 108)	θ value	3.0926 (rank : 174)
Query Neighborhood Hits	248	Target Neighborhood Hits	89	Shared Neighborhood Hits	66
SwissProt Accessions	Q3MJ16, Q6ZSC0	Gene names	PLA2G4E
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

CPNE3_HUMAN
NC score	0.169383 (rank : 109)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	248	Target Neighborhood Hits	90	Shared Neighborhood Hits	61
SwissProt Accessions	O75131, Q8IYA1	Gene names	CPNE3, CPN3, KIAA0636
Domain Architecture
Description	Copine-3 (Copine III).

CPNE3_MOUSE
NC score	0.169180 (rank : 110)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	248	Target Neighborhood Hits	90	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BT60, Q5CZX9, Q5DU22	Gene names	Cpne3, Kiaa0636
Domain Architecture
Description	Copine-3 (Copine III).

PA24B_HUMAN
NC score	0.165754 (rank : 111)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	248	Target Neighborhood Hits	89	Shared Neighborhood Hits	63
SwissProt Accessions	O95712, Q59GF9, Q8TB10, Q9UKV7	Gene names	PLA2G4B
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

PA24A_HUMAN
NC score	0.162537 (rank : 112)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	248	Target Neighborhood Hits	88	Shared Neighborhood Hits	70
SwissProt Accessions	P47712	Gene names	PLA2G4A, CPLA2, PLA2G4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

CPNE5_HUMAN
NC score	0.160988 (rank : 113)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	248	Target Neighborhood Hits	88	Shared Neighborhood Hits	62
SwissProt Accessions	Q9HCH3	Gene names	CPNE5, KIAA1599
Domain Architecture
Description	Copine-5 (Copine V).

CPNE5_MOUSE
NC score	0.159739 (rank : 114)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	248	Target Neighborhood Hits	86	Shared Neighborhood Hits	62
SwissProt Accessions	Q8JZW4	Gene names	Cpne5
Domain Architecture
Description	Copine-5 (Copine V).

CPNE8_HUMAN
NC score	0.155595 (rank : 115)	θ value	2.36792 (rank : 155)
Query Neighborhood Hits	248	Target Neighborhood Hits	86	Shared Neighborhood Hits	62
SwissProt Accessions	Q86YQ8, Q2TB41	Gene names	CPNE8
Domain Architecture
Description	Copine-8 (Copine VIII).

CPNE7_HUMAN
NC score	0.152578 (rank : 116)	θ value	0.279714 (rank : 107)
Query Neighborhood Hits	248	Target Neighborhood Hits	92	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UBL6	Gene names	CPNE7
Domain Architecture
Description	Copine-7 (Copine VII).

CPNE8_MOUSE
NC score	0.152015 (rank : 117)	θ value	2.36792 (rank : 156)
Query Neighborhood Hits	248	Target Neighborhood Hits	85	Shared Neighborhood Hits	62
SwissProt Accessions	Q9DC53, Q9CUZ8	Gene names	Cpne8
Domain Architecture
Description	Copine-8 (Copine VIII).

ITSN2_HUMAN
NC score	0.149251 (rank : 118)	θ value	2.36792 (rank : 160)
Query Neighborhood Hits	248	Target Neighborhood Hits	1173	Shared Neighborhood Hits	95
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

CPNE2_MOUSE
NC score	0.146562 (rank : 119)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	248	Target Neighborhood Hits	82	Shared Neighborhood Hits	57
SwissProt Accessions	P59108, Q8K1D7	Gene names	Cpne2
Domain Architecture
Description	Copine-2 (Copine II).

CPNE1_MOUSE
NC score	0.146484 (rank : 120)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	248	Target Neighborhood Hits	83	Shared Neighborhood Hits	59
SwissProt Accessions	Q8C166, Q925K4, Q925K5	Gene names	Cpne1
Domain Architecture
Description	Copine-1 (Copine I).

CPNE2_HUMAN
NC score	0.144980 (rank : 121)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	248	Target Neighborhood Hits	75	Shared Neighborhood Hits	54
SwissProt Accessions	Q96FN4, Q68D19, Q86XP9	Gene names	CPNE2
Domain Architecture
Description	Copine-2 (Copine II).

ITSN2_MOUSE
NC score	0.133303 (rank : 122)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	248	Target Neighborhood Hits	1371	Shared Neighborhood Hits	102
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

PA24F_MOUSE
NC score	0.130240 (rank : 123)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	248	Target Neighborhood Hits	93	Shared Neighborhood Hits	58
SwissProt Accessions	Q50L41, Q80VQ8, Q80VV9	Gene names	Pla2g4f
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

CPNE1_HUMAN
NC score	0.122907 (rank : 124)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	248	Target Neighborhood Hits	70	Shared Neighborhood Hits	54
SwissProt Accessions	Q99829, Q6IBL3, Q9H243, Q9NTZ7	Gene names	CPNE1, CPN1
Domain Architecture
Description	Copine-1 (Copine I).

PLCD1_HUMAN
NC score	0.114400 (rank : 125)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	248	Target Neighborhood Hits	93	Shared Neighborhood Hits	51
SwissProt Accessions	P51178	Gene names	PLCD1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

PA24F_HUMAN
NC score	0.110658 (rank : 126)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	248	Target Neighborhood Hits	78	Shared Neighborhood Hits	56
SwissProt Accessions	Q68DD2, Q6ZMC8	Gene names	PLA2G4F
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

CPNE6_HUMAN
NC score	0.108958 (rank : 127)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	248	Target Neighborhood Hits	85	Shared Neighborhood Hits	55
SwissProt Accessions	O95741, Q53HA6, Q8WVG1	Gene names	CPNE6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

CPNE6_MOUSE
NC score	0.107634 (rank : 128)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	248	Target Neighborhood Hits	87	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Z140	Gene names	Cpne6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

ITSN1_MOUSE
NC score	0.106554 (rank : 129)	θ value	1.81305 (rank : 150)
Query Neighborhood Hits	248	Target Neighborhood Hits	1669	Shared Neighborhood Hits	119
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

SMUF1_HUMAN
NC score	0.104586 (rank : 130)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	248	Target Neighborhood Hits	135	Shared Neighborhood Hits	54
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

ITSN1_HUMAN
NC score	0.104466 (rank : 131)	θ value	1.81305 (rank : 149)
Query Neighborhood Hits	248	Target Neighborhood Hits	1757	Shared Neighborhood Hits	112
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

SMUF1_MOUSE
NC score	0.103425 (rank : 132)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	248	Target Neighborhood Hits	142	Shared Neighborhood Hits	54
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

SMUF2_HUMAN
NC score	0.103231 (rank : 133)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	248	Target Neighborhood Hits	142	Shared Neighborhood Hits	55
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

WWC1_MOUSE
NC score	0.101420 (rank : 134)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	248	Target Neighborhood Hits	290	Shared Neighborhood Hits	36
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

CPNE4_HUMAN
NC score	0.097075 (rank : 135)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	248	Target Neighborhood Hits	70	Shared Neighborhood Hits	50
SwissProt Accessions	Q96A23, Q8TEX1	Gene names	CPNE4
Domain Architecture
Description	Copine-4 (Copine IV) (Copine-8).

CPNE4_MOUSE
NC score	0.093547 (rank : 136)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	248	Target Neighborhood Hits	67	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BLR2	Gene names	Cpne4
Domain Architecture	No domain graphic available
Description	Copine-4 (Copine IV).

SYT8_HUMAN
NC score	0.077988 (rank : 137)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	248	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NBV8, Q9NSV9	Gene names	SYT8
Domain Architecture	No domain graphic available
Description	Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII).

PLCD1_MOUSE
NC score	0.076665 (rank : 138)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	248	Target Neighborhood Hits	106	Shared Neighborhood Hits	48
SwissProt Accessions	Q8R3B1	Gene names	Plcd1, Plcd
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

WWC1_HUMAN
NC score	0.072309 (rank : 139)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	248	Target Neighborhood Hits	290	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

SRRM2_MOUSE
NC score	0.071670 (rank : 140)	θ value	0.163984 (rank : 100)
Query Neighborhood Hits	248	Target Neighborhood Hits	1470	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

RASA1_HUMAN
NC score	0.067831 (rank : 141)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	248	Target Neighborhood Hits	258	Shared Neighborhood Hits	25
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

SRRM2_HUMAN
NC score	0.065201 (rank : 142)	θ value	0.365318 (rank : 113)
Query Neighborhood Hits	248	Target Neighborhood Hits	1296	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

BSN_MOUSE
NC score	0.064301 (rank : 143)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	248	Target Neighborhood Hits	2057	Shared Neighborhood Hits	71
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

BSN_HUMAN
NC score	0.063358 (rank : 144)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	248	Target Neighborhood Hits	1537	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

DAB2P_HUMAN
NC score	0.061811 (rank : 145)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	248	Target Neighborhood Hits	303	Shared Neighborhood Hits	23
SwissProt Accessions	Q5VWQ8, Q8TDL2, Q96SE1, Q9C0C0	Gene names	DAB2IP, AF9Q34, AIP1, KIAA1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein) (DAB2 interaction protein) (ASK-interacting protein 1).

BASP_HUMAN
NC score	0.060344 (rank : 146)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	248	Target Neighborhood Hits	321	Shared Neighborhood Hits	32
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

DAB2P_MOUSE
NC score	0.059282 (rank : 147)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	248	Target Neighborhood Hits	284	Shared Neighborhood Hits	21
SwissProt Accessions	Q3UHC7, Q3TPD5, Q3UH44, Q6JTV1, Q80T97	Gene names	Dab2ip, Kiaa1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein).

PK3CG_HUMAN
NC score	0.058302 (rank : 148)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	248	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	P48736, Q8IV23, Q9BZC8	Gene names	PIK3CG
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

PK3CG_MOUSE
NC score	0.058131 (rank : 149)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	248	Target Neighborhood Hits	43	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JHG7	Gene names	Pik3cg, Pi3kg1
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

PK3CA_MOUSE
NC score	0.056710 (rank : 150)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	248	Target Neighborhood Hits	48	Shared Neighborhood Hits	7
SwissProt Accessions	P42337	Gene names	Pik3ca
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).

PK3CA_HUMAN
NC score	0.056642 (rank : 151)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	248	Target Neighborhood Hits	45	Shared Neighborhood Hits	7
SwissProt Accessions	P42336, Q99762	Gene names	PIK3CA
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).

IWS1_HUMAN
NC score	0.055929 (rank : 152)	θ value	0.21417 (rank : 104)
Query Neighborhood Hits	248	Target Neighborhood Hits	1241	Shared Neighborhood Hits	86
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PK3CD_HUMAN
NC score	0.054056 (rank : 153)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	248	Target Neighborhood Hits	40	Shared Neighborhood Hits	7
SwissProt Accessions	O00329, O15445	Gene names	PIK3CD
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit delta) (PtdIns-3- kinase p110) (PI3K) (p110delta).

PK3CD_MOUSE
NC score	0.053948 (rank : 154)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	248	Target Neighborhood Hits	42	Shared Neighborhood Hits	6
SwissProt Accessions	O35904	Gene names	Pik3cd
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit delta) (PtdIns-3- kinase p110) (PI3K) (p110delta).

MARCS_HUMAN
NC score	0.053553 (rank : 155)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	248	Target Neighborhood Hits	204	Shared Neighborhood Hits	17
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

PK3CB_MOUSE
NC score	0.053497 (rank : 156)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	248	Target Neighborhood Hits	49	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BTI9	Gene names	Pik3cb
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).

PK3CB_HUMAN
NC score	0.053474 (rank : 157)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	248	Target Neighborhood Hits	43	Shared Neighborhood Hits	6
SwissProt Accessions	P42338	Gene names	PIK3CB
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).

SRRM1_MOUSE
NC score	0.052483 (rank : 158)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	248	Target Neighborhood Hits	966	Shared Neighborhood Hits	61
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

PI4KB_HUMAN
NC score	0.052355 (rank : 159)	θ value	4.03905 (rank : 193)
Query Neighborhood Hits	248	Target Neighborhood Hits	79	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UBF8, O15096, P78405, Q9BWR6	Gene names	PIK4CB, PI4KB
Domain Architecture
Description	Phosphatidylinositol 4-kinase beta (EC 2.7.1.67) (PtdIns 4-kinase beta) (PI4Kbeta) (PI4K-beta) (NPIK) (PI4K92).

PDZD8_HUMAN
NC score	0.052308 (rank : 160)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	248	Target Neighborhood Hits	185	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

TGON2_HUMAN
NC score	0.051854 (rank : 161)	θ value	0.125558 (rank : 97)
Query Neighborhood Hits	248	Target Neighborhood Hits	1037	Shared Neighborhood Hits	70
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

SRRM1_HUMAN
NC score	0.051572 (rank : 162)	θ value	6.88961 (rank : 225)
Query Neighborhood Hits	248	Target Neighborhood Hits	690	Shared Neighborhood Hits	51
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

WWP1_HUMAN
NC score	0.051559 (rank : 163)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	248	Target Neighborhood Hits	262	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

NOLC1_HUMAN
NC score	0.051070 (rank : 164)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	248	Target Neighborhood Hits	452	Shared Neighborhood Hits	52
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

PK3C3_HUMAN
NC score	0.051031 (rank : 165)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	248	Target Neighborhood Hits	49	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NEB9, Q15134	Gene names	PIK3C3
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC 2.7.1.137) (PtdIns-3-kinase type 3) (PI3-kinase type 3) (PI3K type 3) (Phosphoinositide-3-kinase class 3) (Phosphatidylinositol 3-kinase p100 subunit).

PI4KA_HUMAN
NC score	0.050988 (rank : 166)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	248	Target Neighborhood Hits	53	Shared Neighborhood Hits	6
SwissProt Accessions	P42356, Q7Z625, Q9UPG2	Gene names	PIK4CA, PIK4
Domain Architecture
Description	Phosphatidylinositol 4-kinase alpha (EC 2.7.1.67) (PI4-kinase alpha) (PtdIns-4-kinase alpha) (PI4K-alpha).

PK3C3_MOUSE
NC score	0.050854 (rank : 167)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	248	Target Neighborhood Hits	49	Shared Neighborhood Hits	7
SwissProt Accessions	Q6PF93, Q8R3S8	Gene names	Pik3c3
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC 2.7.1.137) (PtdIns-3-kinase type 3) (PI3-kinase type 3) (PI3K type 3) (Phosphoinositide-3-kinase class 3).

SYGP1_HUMAN
NC score	0.050646 (rank : 168)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	248	Target Neighborhood Hits	589	Shared Neighborhood Hits	29
SwissProt Accessions	Q96PV0, Q8TCS2, Q9UGE2	Gene names	SYNGAP1, KIAA1938
Domain Architecture
Description	Ras GTPase-activating protein SynGAP (Synaptic Ras-GTPase-activating protein 1) (Synaptic Ras-GAP 1) (Neuronal RasGAP).

NGAP_HUMAN
NC score	0.050596 (rank : 169)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	248	Target Neighborhood Hits	517	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UJF2, O95174, Q5TFU9	Gene names	RASAL2, NGAP
Domain Architecture
Description	Ras GTPase-activating protein nGAP (RAS protein activator-like 1).

CBP_MOUSE
NC score	0.046835 (rank : 170)	θ value	0.21417 (rank : 103)
Query Neighborhood Hits	248	Target Neighborhood Hits	1051	Shared Neighborhood Hits	54
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

MDC1_MOUSE
NC score	0.045677 (rank : 171)	θ value	0.0330416 (rank : 90)
Query Neighborhood Hits	248	Target Neighborhood Hits	998	Shared Neighborhood Hits	58
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

NIPBL_HUMAN
NC score	0.042354 (rank : 172)	θ value	8.99809 (rank : 240)
Query Neighborhood Hits	248	Target Neighborhood Hits	1311	Shared Neighborhood Hits	83
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NPBL_MOUSE
NC score	0.042326 (rank : 173)	θ value	0.62314 (rank : 122)
Query Neighborhood Hits	248	Target Neighborhood Hits	1041	Shared Neighborhood Hits	71
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

MINT_HUMAN
NC score	0.041415 (rank : 174)	θ value	0.47712 (rank : 116)
Query Neighborhood Hits	248	Target Neighborhood Hits	1291	Shared Neighborhood Hits	69
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

CBP_HUMAN
NC score	0.040369 (rank : 175)	θ value	0.62314 (rank : 120)
Query Neighborhood Hits	248	Target Neighborhood Hits	941	Shared Neighborhood Hits	47
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

TXND2_MOUSE
NC score	0.039792 (rank : 176)	θ value	3.0926 (rank : 177)
Query Neighborhood Hits	248	Target Neighborhood Hits	828	Shared Neighborhood Hits	68
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

ADDB_MOUSE
NC score	0.039137 (rank : 177)	θ value	0.163984 (rank : 98)
Query Neighborhood Hits	248	Target Neighborhood Hits	574	Shared Neighborhood Hits	48
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

OGFR_HUMAN
NC score	0.039113 (rank : 178)	θ value	3.0926 (rank : 173)
Query Neighborhood Hits	248	Target Neighborhood Hits	1582	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

RBBP6_MOUSE
NC score	0.038811 (rank : 179)	θ value	5.27518 (rank : 213)
Query Neighborhood Hits	248	Target Neighborhood Hits	1014	Shared Neighborhood Hits	61
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

MINT_MOUSE
NC score	0.038669 (rank : 180)	θ value	5.27518 (rank : 209)
Query Neighborhood Hits	248	Target Neighborhood Hits	1514	Shared Neighborhood Hits	78
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

DMP1_MOUSE
NC score	0.034584 (rank : 181)	θ value	5.27518 (rank : 204)
Query Neighborhood Hits	248	Target Neighborhood Hits	498	Shared Neighborhood Hits	47
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

DMP1_HUMAN
NC score	0.034314 (rank : 182)	θ value	1.06291 (rank : 132)
Query Neighborhood Hits	248	Target Neighborhood Hits	491	Shared Neighborhood Hits	42
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

CENPR_HUMAN
NC score	0.034134 (rank : 183)	θ value	0.365318 (rank : 111)
Query Neighborhood Hits	248	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	Q13352, Q13353, Q5RJ42, Q5RJ44, Q5RJ45, Q7KYX2, Q96CD5, Q9UKB6	Gene names	ITGB3BP, CENPR, NRIF3
Domain Architecture	No domain graphic available
Description	Centromere protein R (CENP-R) (Nuclear receptor-interacting factor 3) (Integrin beta-3-binding protein) (Beta3-endonexin).

JHD2A_MOUSE
NC score	0.032671 (rank : 184)	θ value	0.813845 (rank : 128)
Query Neighborhood Hits	248	Target Neighborhood Hits	123	Shared Neighborhood Hits	17
SwissProt Accessions	Q6PCM1, Q2MJQ6, Q3TKW8, Q3UML3, Q6ZQ57, Q8K2J6, Q8K2K4, Q8R350	Gene names	Jmjd1a, Jhdm2a, Kiaa0742
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2A (EC 1.14.11.-) (Jumonji domain-containing protein 1A).

K0240_MOUSE
NC score	0.032225 (rank : 185)	θ value	2.36792 (rank : 161)
Query Neighborhood Hits	248	Target Neighborhood Hits	211	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CHH5	Gene names	Kiaa0240
Domain Architecture	No domain graphic available
Description	Protein KIAA0240.

NCOA6_HUMAN
NC score	0.032148 (rank : 186)	θ value	1.38821 (rank : 141)
Query Neighborhood Hits	248	Target Neighborhood Hits	1202	Shared Neighborhood Hits	53
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

LEO1_HUMAN
NC score	0.031697 (rank : 187)	θ value	5.27518 (rank : 207)
Query Neighborhood Hits	248	Target Neighborhood Hits	958	Shared Neighborhood Hits	53
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

JHD2C_HUMAN
NC score	0.031107 (rank : 188)	θ value	0.163984 (rank : 99)
Query Neighborhood Hits	248	Target Neighborhood Hits	279	Shared Neighborhood Hits	28
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

ALO17_HUMAN
NC score	0.031100 (rank : 189)	θ value	3.0926 (rank : 167)
Query Neighborhood Hits	248	Target Neighborhood Hits	317	Shared Neighborhood Hits	25
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

NASP_HUMAN
NC score	0.030805 (rank : 190)	θ value	8.99809 (rank : 239)
Query Neighborhood Hits	248	Target Neighborhood Hits	709	Shared Neighborhood Hits	50
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

MAP1B_HUMAN
NC score	0.030331 (rank : 191)	θ value	8.99809 (rank : 237)
Query Neighborhood Hits	248	Target Neighborhood Hits	903	Shared Neighborhood Hits	64
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

TGON1_MOUSE
NC score	0.029954 (rank : 192)	θ value	5.27518 (rank : 214)
Query Neighborhood Hits	248	Target Neighborhood Hits	243	Shared Neighborhood Hits	31
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

PARG_MOUSE
NC score	0.029780 (rank : 193)	θ value	0.62314 (rank : 123)
Query Neighborhood Hits	248	Target Neighborhood Hits	54	Shared Neighborhood Hits	8
SwissProt Accessions	O88622, Q80YQ6, Q8CB72	Gene names	Parg
Domain Architecture	No domain graphic available
Description	Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143).

CTR9_MOUSE
NC score	0.029346 (rank : 194)	θ value	1.38821 (rank : 137)
Query Neighborhood Hits	248	Target Neighborhood Hits	427	Shared Neighborhood Hits	31
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

JHD2A_HUMAN
NC score	0.029056 (rank : 195)	θ value	1.38821 (rank : 138)
Query Neighborhood Hits	248	Target Neighborhood Hits	118	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y4C1, Q53S72, Q68D47, Q68UT9, Q6N050, Q8IY08	Gene names	JMJD1A, JHDM2A, JMJD1, KIAA0742
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2A (EC 1.14.11.-) (Jumonji domain-containing protein 1A).

MAP2_MOUSE
NC score	0.028911 (rank : 196)	θ value	1.06291 (rank : 133)
Query Neighborhood Hits	248	Target Neighborhood Hits	342	Shared Neighborhood Hits	36
SwissProt Accessions	P20357	Gene names	Map2, Mtap2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2).

APXL_HUMAN
NC score	0.028637 (rank : 197)	θ value	0.365318 (rank : 110)
Query Neighborhood Hits	248	Target Neighborhood Hits	553	Shared Neighborhood Hits	30
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

RAI1_MOUSE
NC score	0.027716 (rank : 198)	θ value	0.813845 (rank : 129)
Query Neighborhood Hits	248	Target Neighborhood Hits	344	Shared Neighborhood Hits	23
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

PARG_HUMAN
NC score	0.027306 (rank : 199)	θ value	2.36792 (rank : 163)
Query Neighborhood Hits	248	Target Neighborhood Hits	97	Shared Neighborhood Hits	12
SwissProt Accessions	Q86W56, Q6E4P6, Q6E4P7, Q7Z742, Q9Y4W7	Gene names	PARG
Domain Architecture	No domain graphic available
Description	Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143).

RTN4_MOUSE
NC score	0.027214 (rank : 200)	θ value	0.47712 (rank : 117)
Query Neighborhood Hits	248	Target Neighborhood Hits	341	Shared Neighborhood Hits	27
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

TITIN_HUMAN
NC score	0.027026 (rank : 201)	θ value	1.43324e-05 (rank : 65)
Query Neighborhood Hits	248	Target Neighborhood Hits	2923	Shared Neighborhood Hits	81
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

AFF1_MOUSE
NC score	0.026612 (rank : 202)	θ value	1.81305 (rank : 144)
Query Neighborhood Hits	248	Target Neighborhood Hits	351	Shared Neighborhood Hits	35
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

K0240_HUMAN
NC score	0.026198 (rank : 203)	θ value	1.38821 (rank : 139)
Query Neighborhood Hits	248	Target Neighborhood Hits	96	Shared Neighborhood Hits	12
SwissProt Accessions	Q6AI39, Q5TFZ3, Q92514	Gene names	KIAA0240
Domain Architecture	No domain graphic available
Description	Protein KIAA0240.

BAT3_MOUSE
NC score	0.025577 (rank : 204)	θ value	5.27518 (rank : 200)
Query Neighborhood Hits	248	Target Neighborhood Hits	518	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

REPS1_MOUSE
NC score	0.025544 (rank : 205)	θ value	0.365318 (rank : 112)
Query Neighborhood Hits	248	Target Neighborhood Hits	204	Shared Neighborhood Hits	20
SwissProt Accessions	O54916, Q8C9J9, Q99LR8	Gene names	Reps1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

GLU2B_HUMAN
NC score	0.025478 (rank : 206)	θ value	8.99809 (rank : 234)
Query Neighborhood Hits	248	Target Neighborhood Hits	377	Shared Neighborhood Hits	27
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

BRCA2_HUMAN
NC score	0.025188 (rank : 207)	θ value	0.21417 (rank : 101)
Query Neighborhood Hits	248	Target Neighborhood Hits	202	Shared Neighborhood Hits	12
SwissProt Accessions	P51587, O00183, O15008, Q13879	Gene names	BRCA2, FANCD1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein).

BBX_MOUSE
NC score	0.024280 (rank : 208)	θ value	0.813845 (rank : 126)
Query Neighborhood Hits	248	Target Neighborhood Hits	152	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VBW5, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VI48, Q8VI49, Q8VI50, Q9CS94	Gene names	Bbx, Hbp2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

AKAP6_HUMAN
NC score	0.024233 (rank : 209)	θ value	0.365318 (rank : 109)
Query Neighborhood Hits	248	Target Neighborhood Hits	263	Shared Neighborhood Hits	12
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

BAT3_HUMAN
NC score	0.023761 (rank : 210)	θ value	4.03905 (rank : 183)
Query Neighborhood Hits	248	Target Neighborhood Hits	490	Shared Neighborhood Hits	25
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

FANCJ_HUMAN
NC score	0.023676 (rank : 211)	θ value	0.125558 (rank : 96)
Query Neighborhood Hits	248	Target Neighborhood Hits	72	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BX63, Q8NCI5	Gene names	BRIP1, BACH1, FANCJ
Domain Architecture	No domain graphic available
Description	Fanconi anemia group J protein (EC 3.6.1.-) (ATP-dependent RNA helicase BRIP1) (Protein FACJ) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1) (BRCA1-associated C-terminal helicase 1).

DOCK4_MOUSE
NC score	0.023586 (rank : 212)	θ value	0.47712 (rank : 115)
Query Neighborhood Hits	248	Target Neighborhood Hits	210	Shared Neighborhood Hits	26
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

MLL3_MOUSE
NC score	0.023390 (rank : 213)	θ value	5.27518 (rank : 210)
Query Neighborhood Hits	248	Target Neighborhood Hits	1399	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

DOCK4_HUMAN
NC score	0.022750 (rank : 214)	θ value	1.81305 (rank : 145)
Query Neighborhood Hits	248	Target Neighborhood Hits	237	Shared Neighborhood Hits	24
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

RNF38_HUMAN
NC score	0.022711 (rank : 215)	θ value	0.62314 (rank : 124)
Query Neighborhood Hits	248	Target Neighborhood Hits	155	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H0F5, Q8N0Y0	Gene names	RNF38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

ARI5B_HUMAN
NC score	0.022329 (rank : 216)	θ value	6.88961 (rank : 217)
Query Neighborhood Hits	248	Target Neighborhood Hits	328	Shared Neighborhood Hits	31
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

SOX13_HUMAN
NC score	0.022204 (rank : 217)	θ value	0.21417 (rank : 105)
Query Neighborhood Hits	248	Target Neighborhood Hits	464	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

RIF1_MOUSE
NC score	0.022012 (rank : 218)	θ value	1.81305 (rank : 152)
Query Neighborhood Hits	248	Target Neighborhood Hits	315	Shared Neighborhood Hits	34
SwissProt Accessions	Q6PR54, Q6T8D9, Q7TPD8, Q8BTU2, Q8C408, Q9CS77	Gene names	Rif1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1).

ADDA_HUMAN
NC score	0.022002 (rank : 219)	θ value	8.99809 (rank : 227)
Query Neighborhood Hits	248	Target Neighborhood Hits	108	Shared Neighborhood Hits	16
SwissProt Accessions	P35611, Q13734, Q14729, Q16156, Q9UJB6	Gene names	ADD1, ADDA
Domain Architecture
Description	Alpha-adducin (Erythrocyte adducin subunit alpha).

RNF38_MOUSE
NC score	0.021907 (rank : 220)	θ value	0.813845 (rank : 130)
Query Neighborhood Hits	248	Target Neighborhood Hits	153	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BI21, Q6P5B1	Gene names	Rnf38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

ADDB_HUMAN
NC score	0.021852 (rank : 221)	θ value	4.03905 (rank : 180)
Query Neighborhood Hits	248	Target Neighborhood Hits	142	Shared Neighborhood Hits	18
SwissProt Accessions	P35612, Q13482, Q16412, Q59G82, Q5U5P4, Q6P0P2, Q6PGQ4, Q7Z688, Q7Z689, Q7Z690, Q7Z691	Gene names	ADD2, ADDB
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta).

BCAS1_HUMAN
NC score	0.021634 (rank : 222)	θ value	2.36792 (rank : 153)
Query Neighborhood Hits	248	Target Neighborhood Hits	133	Shared Neighborhood Hits	21
SwissProt Accessions	O75363, Q68CZ3	Gene names	BCAS1, AIBC1, NABC1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 1 (Novel amplified in breast cancer 1) (Amplified and overexpressed in breast cancer).

ALMS1_MOUSE
NC score	0.021435 (rank : 223)	θ value	1.06291 (rank : 131)
Query Neighborhood Hits	248	Target Neighborhood Hits	181	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K4E0, Q6A084, Q8C9N9	Gene names	Alms1, Kiaa0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1 homolog.

LPIN2_HUMAN
NC score	0.021247 (rank : 224)	θ value	1.38821 (rank : 140)
Query Neighborhood Hits	248	Target Neighborhood Hits	117	Shared Neighborhood Hits	15
SwissProt Accessions	Q92539	Gene names	LPIN2, KIAA0249
Domain Architecture	No domain graphic available
Description	Lipin-2.

TR150_MOUSE
NC score	0.020989 (rank : 225)	θ value	2.36792 (rank : 164)
Query Neighborhood Hits	248	Target Neighborhood Hits	468	Shared Neighborhood Hits	39
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

ATX2_HUMAN
NC score	0.020905 (rank : 226)	θ value	8.99809 (rank : 228)
Query Neighborhood Hits	248	Target Neighborhood Hits	375	Shared Neighborhood Hits	29
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

XRCC1_MOUSE
NC score	0.020831 (rank : 227)	θ value	3.0926 (rank : 178)
Query Neighborhood Hits	248	Target Neighborhood Hits	242	Shared Neighborhood Hits	18
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

NEB1_HUMAN
NC score	0.020582 (rank : 228)	θ value	0.62314 (rank : 121)
Query Neighborhood Hits	248	Target Neighborhood Hits	829	Shared Neighborhood Hits	38
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

ELOA1_MOUSE
NC score	0.020315 (rank : 229)	θ value	2.36792 (rank : 157)
Query Neighborhood Hits	248	Target Neighborhood Hits	152	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CB77, Q80VB2, Q9R0Q5	Gene names	Tceb3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

K0460_MOUSE
NC score	0.020152 (rank : 230)	θ value	5.27518 (rank : 206)
Query Neighborhood Hits	248	Target Neighborhood Hits	374	Shared Neighborhood Hits	29
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

FIP1_HUMAN
NC score	0.020116 (rank : 231)	θ value	2.36792 (rank : 158)
Query Neighborhood Hits	248	Target Neighborhood Hits	118	Shared Neighborhood Hits	15
SwissProt Accessions	Q6UN15, Q499Y4, Q49AU3, Q7Z608, Q8WVN3, Q96F80, Q9H077	Gene names	FIP1L1, FIP1, RHE
Domain Architecture	No domain graphic available
Description	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1) (Factor interacting with PAP) (hFip1) (Rearranged in hypereosinophilia).

ELOA1_HUMAN
NC score	0.019911 (rank : 232)	θ value	5.27518 (rank : 205)
Query Neighborhood Hits	248	Target Neighborhood Hits	388	Shared Neighborhood Hits	32
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

ATX2_MOUSE
NC score	0.019042 (rank : 233)	θ value	8.99809 (rank : 229)
Query Neighborhood Hits	248	Target Neighborhood Hits	445	Shared Neighborhood Hits	33
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

MFAP1_HUMAN
NC score	0.018800 (rank : 234)	θ value	2.36792 (rank : 162)
Query Neighborhood Hits	248	Target Neighborhood Hits	321	Shared Neighborhood Hits	18
SwissProt Accessions	P55081	Gene names	MFAP1
Domain Architecture
Description	Microfibrillar-associated protein 1.

OS9_HUMAN
NC score	0.018648 (rank : 235)	θ value	4.03905 (rank : 192)
Query Neighborhood Hits	248	Target Neighborhood Hits	134	Shared Neighborhood Hits	14
SwissProt Accessions	Q13438, O00579	Gene names	OS9
Domain Architecture	No domain graphic available
Description	Protein OS-9 precursor (Amplified in osteosarcoma 9).

PRCC_HUMAN
NC score	0.018458 (rank : 236)	θ value	6.88961 (rank : 224)
Query Neighborhood Hits	248	Target Neighborhood Hits	109	Shared Neighborhood Hits	7
SwissProt Accessions	Q92733, O00665, O00724	Gene names	PRCC, TPRC
Domain Architecture	No domain graphic available
Description	Proline-rich protein PRCC (Papillary renal cell carcinoma translocation-associated gene protein).

US6NL_HUMAN
NC score	0.018421 (rank : 237)	θ value	2.36792 (rank : 166)
Query Neighborhood Hits	248	Target Neighborhood Hits	201	Shared Neighborhood Hits	15
SwissProt Accessions	Q92738, Q15400, Q7L0K9	Gene names	USP6NL, KIAA0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN- tre).

CD2L1_MOUSE
NC score	0.018246 (rank : 238)	θ value	5.27518 (rank : 202)
Query Neighborhood Hits	248	Target Neighborhood Hits	1463	Shared Neighborhood Hits	57
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

MFAP1_MOUSE
NC score	0.017158 (rank : 239)	θ value	3.0926 (rank : 172)
Query Neighborhood Hits	248	Target Neighborhood Hits	353	Shared Neighborhood Hits	18
SwissProt Accessions	Q9CQU1, Q3TU29, Q8CCL1, Q9CSJ5	Gene names	Mfap1
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 1.

ZDHC5_HUMAN
NC score	0.016328 (rank : 240)	θ value	0.62314 (rank : 125)
Query Neighborhood Hits	248	Target Neighborhood Hits	106	Shared Neighborhood Hits	6
SwissProt Accessions	Q9C0B5, Q6ZMF0, Q8TAK8, Q9H923, Q9UFI7	Gene names	ZDHHC5, KIAA1748, ZNF375
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC5 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 5) (DHHC-5) (Zinc finger protein 375).

ZDHC5_MOUSE
NC score	0.016262 (rank : 241)	θ value	1.06291 (rank : 134)
Query Neighborhood Hits	248	Target Neighborhood Hits	113	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VDZ4, Q69ZB5, Q8R2X7	Gene names	Zdhhc5, Kiaa1748
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC5 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 5) (DHHC-5).

GP156_HUMAN
NC score	0.016188 (rank : 242)	θ value	1.81305 (rank : 148)
Query Neighborhood Hits	248	Target Neighborhood Hits	84	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NFN8, Q86SN6	Gene names	GPR156, GABABL, PGR28
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor) (G-protein coupled receptor PGR28).

WNK4_HUMAN
NC score	0.015807 (rank : 243)	θ value	0.365318 (rank : 114)
Query Neighborhood Hits	248	Target Neighborhood Hits	1043	Shared Neighborhood Hits	33
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

GAB1_HUMAN
NC score	0.015522 (rank : 244)	θ value	4.03905 (rank : 189)
Query Neighborhood Hits	248	Target Neighborhood Hits	279	Shared Neighborhood Hits	20
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

CAF1B_MOUSE
NC score	0.015080 (rank : 245)	θ value	0.21417 (rank : 102)
Query Neighborhood Hits	248	Target Neighborhood Hits	385	Shared Neighborhood Hits	20
SwissProt Accessions	Q9D0N7	Gene names	Chaf1b
Domain Architecture
Description	Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60).

GASP1_MOUSE
NC score	0.014562 (rank : 246)	θ value	1.81305 (rank : 147)
Query Neighborhood Hits	248	Target Neighborhood Hits	169	Shared Neighborhood Hits	19
SwissProt Accessions	Q5U4C1, Q8BKR8, Q8BUN4, Q8BYK9, Q8CHF4, Q8R095	Gene names	Gprasp1, Kiaa0443
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 1 (GASP-1).

C8AP2_MOUSE
NC score	0.014412 (rank : 247)	θ value	6.88961 (rank : 218)
Query Neighborhood Hits	248	Target Neighborhood Hits	405	Shared Neighborhood Hits	37
SwissProt Accessions	Q9WUF3, Q9CSW2	Gene names	Casp8ap2, Flash
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

CD2L1_HUMAN
NC score	0.014296 (rank : 248)	θ value	4.03905 (rank : 185)
Query Neighborhood Hits	248	Target Neighborhood Hits	1467	Shared Neighborhood Hits	58
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

ZG14_MOUSE
NC score	0.014155 (rank : 249)	θ value	4.03905 (rank : 198)
Query Neighborhood Hits	248	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D1C9, Q3TWT8, Q8CCK8	Gene names
Domain Architecture	No domain graphic available
Description	Gastric cancer antigen Zg14 homolog.

TACT_HUMAN
NC score	0.013966 (rank : 250)	θ value	4.03905 (rank : 196)
Query Neighborhood Hits	248	Target Neighborhood Hits	100	Shared Neighborhood Hits	4
SwissProt Accessions	P40200	Gene names	CD96
Domain Architecture	No domain graphic available
Description	T-cell surface protein tactile precursor (T cell-activated increased late expression protein) (CD96 antigen).

N4BP2_HUMAN
NC score	0.013829 (rank : 251)	θ value	4.03905 (rank : 191)
Query Neighborhood Hits	248	Target Neighborhood Hits	107	Shared Neighborhood Hits	7
SwissProt Accessions	Q86UW6, Q9NVK2, Q9P2D4	Gene names	N4BP2, B3BP, KIAA1413
Domain Architecture
Description	NEDD4-binding protein 2 (EC 3.-.-.-) (N4BP2) (BCL-3-binding protein).

ZCH11_HUMAN
NC score	0.013732 (rank : 252)	θ value	8.99809 (rank : 248)
Query Neighborhood Hits	248	Target Neighborhood Hits	278	Shared Neighborhood Hits	22
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

TEX15_HUMAN
NC score	0.013534 (rank : 253)	θ value	6.88961 (rank : 226)
Query Neighborhood Hits	248	Target Neighborhood Hits	174	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BXT5	Gene names	TEX15
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 15 protein.

PPIG_HUMAN
NC score	0.013532 (rank : 254)	θ value	4.03905 (rank : 194)
Query Neighborhood Hits	248	Target Neighborhood Hits	670	Shared Neighborhood Hits	55
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

CD2L2_HUMAN
NC score	0.013486 (rank : 255)	θ value	4.03905 (rank : 186)
Query Neighborhood Hits	248	Target Neighborhood Hits	1439	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

NHEJ1_MOUSE
NC score	0.013328 (rank : 256)	θ value	5.27518 (rank : 212)
Query Neighborhood Hits	248	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	Q3KNJ2, Q99JK0, Q9D9U0	Gene names	Nhej1, Xlf
Domain Architecture	No domain graphic available
Description	Non-homologous end-joining factor 1 (Protein cernunnos) (XRCC4-like factor).

CEND1_HUMAN
NC score	0.013205 (rank : 257)	θ value	2.36792 (rank : 154)
Query Neighborhood Hits	248	Target Neighborhood Hits	284	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

ZO2_HUMAN
NC score	0.013112 (rank : 258)	θ value	3.0926 (rank : 179)
Query Neighborhood Hits	248	Target Neighborhood Hits	289	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

FA35A_MOUSE
NC score	0.012967 (rank : 259)	θ value	6.88961 (rank : 220)
Query Neighborhood Hits	248	Target Neighborhood Hits	54	Shared Neighborhood Hits	8
SwissProt Accessions	Q3UEN2	Gene names	Fam35a
Domain Architecture	No domain graphic available
Description	Protein FAM35A.

TRI66_HUMAN
NC score	0.012463 (rank : 260)	θ value	3.0926 (rank : 176)
Query Neighborhood Hits	248	Target Neighborhood Hits	479	Shared Neighborhood Hits	19
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

RHG07_HUMAN
NC score	0.012329 (rank : 261)	θ value	1.38821 (rank : 142)
Query Neighborhood Hits	248	Target Neighborhood Hits	108	Shared Neighborhood Hits	7
SwissProt Accessions	Q96QB1, O14868, O43199, Q9C0E0	Gene names	DLC1, ARHGAP7, KIAA1723, STARD12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

RHG07_MOUSE
NC score	0.012054 (rank : 262)	θ value	1.38821 (rank : 143)
Query Neighborhood Hits	248	Target Neighborhood Hits	103	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

MYOZ3_MOUSE
NC score	0.011905 (rank : 263)	θ value	4.03905 (rank : 190)
Query Neighborhood Hits	248	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R4E4	Gene names	Myoz3
Domain Architecture	No domain graphic available
Description	Myozenin-3 (Calsarcin-3) (FATZ-related protein 3).

NOL8_HUMAN
NC score	0.011872 (rank : 264)	θ value	8.99809 (rank : 241)
Query Neighborhood Hits	248	Target Neighborhood Hits	297	Shared Neighborhood Hits	25
SwissProt Accessions	Q76FK4, Q5TCC7, Q5TCC8, Q5TCD3, Q5TCD5, Q5TCD6, Q5TCD7, Q76D35, Q7L3E2, Q9H586, Q9H795, Q9H7W7, Q9H9J6, Q9NWA4, Q9NWM4	Gene names	NOL8, NOP132
Domain Architecture	No domain graphic available
Description	Nucleolar protein 8 (Nucleolar protein Nop132).

NFM_HUMAN
NC score	0.011864 (rank : 265)	θ value	6.88961 (rank : 223)
Query Neighborhood Hits	248	Target Neighborhood Hits	1328	Shared Neighborhood Hits	68
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

AKA11_HUMAN
NC score	0.011705 (rank : 266)	θ value	6.88961 (rank : 216)
Query Neighborhood Hits	248	Target Neighborhood Hits	57	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UKA4, O75124, Q9NUK7	Gene names	AKAP11, AKAP220, KIAA0629
Domain Architecture
Description	A-kinase anchor protein 11 (Protein kinase A-anchoring protein 11) (PRKA11) (A kinase anchor protein 220 kDa) (AKAP 220) (hAKAP220).

MO4L2_HUMAN
NC score	0.011612 (rank : 267)	θ value	5.27518 (rank : 211)
Query Neighborhood Hits	248	Target Neighborhood Hits	90	Shared Neighborhood Hits	8
SwissProt Accessions	Q15014, Q567V0, Q8J026	Gene names	MORF4L2, KIAA0026, MRGX
Domain Architecture
Description	Mortality factor 4-like protein 2 (MORF-related gene X protein) (Transcription factor-like protein MRGX) (MSL3-2 protein).

CCD93_HUMAN
NC score	0.011470 (rank : 268)	θ value	1.38821 (rank : 136)
Query Neighborhood Hits	248	Target Neighborhood Hits	600	Shared Neighborhood Hits	21
SwissProt Accessions	Q567U6, Q4LE78, Q53TJ2, Q8TBX5, Q9H6R5, Q9NV15	Gene names	CCDC93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

SAS6_MOUSE
NC score	0.011470 (rank : 269)	θ value	0.47712 (rank : 118)
Query Neighborhood Hits	248	Target Neighborhood Hits	931	Shared Neighborhood Hits	20
SwissProt Accessions	Q80UK7, Q9CYT4	Gene names	Sass6, Sas6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog.

AP3B1_MOUSE
NC score	0.011384 (rank : 270)	θ value	5.27518 (rank : 199)
Query Neighborhood Hits	248	Target Neighborhood Hits	302	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

SOS1_HUMAN
NC score	0.011162 (rank : 271)	θ value	4.03905 (rank : 195)
Query Neighborhood Hits	248	Target Neighborhood Hits	274	Shared Neighborhood Hits	21
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

CK5P2_HUMAN
NC score	0.010941 (rank : 272)	θ value	0.279714 (rank : 106)
Query Neighborhood Hits	248	Target Neighborhood Hits	1433	Shared Neighborhood Hits	44
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

DNM3A_MOUSE
NC score	0.010916 (rank : 273)	θ value	3.0926 (rank : 168)
Query Neighborhood Hits	248	Target Neighborhood Hits	91	Shared Neighborhood Hits	7
SwissProt Accessions	O88508, Q3UH24, Q8CJ60, Q922J0, Q9CSE1	Gene names	Dnmt3a
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase MmuIIIA) (DNA MTase MmuIIIA) (M.MmuIIIA).

GRIPE_MOUSE
NC score	0.010903 (rank : 274)	θ value	3.0926 (rank : 169)
Query Neighborhood Hits	248	Target Neighborhood Hits	70	Shared Neighborhood Hits	5
SwissProt Accessions	Q6GYP7, Q6GYP6, Q6ZQ28, Q8BNJ5, Q8C9G8, Q8CIW4, Q9JMC4	Gene names	Garnl1, Kiaa0884, Tulip1
Domain Architecture	No domain graphic available
Description	GTPase-activating RapGAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

BUB1_HUMAN
NC score	0.010597 (rank : 275)	θ value	8.99809 (rank : 230)
Query Neighborhood Hits	248	Target Neighborhood Hits	543	Shared Neighborhood Hits	16
SwissProt Accessions	O43683, O43430, O43643, O60626	Gene names	BUB1, BUB1L
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 (EC 2.7.11.1) (hBUB1) (BUB1A).

MCPH1_HUMAN
NC score	0.009716 (rank : 276)	θ value	6.88961 (rank : 222)
Query Neighborhood Hits	248	Target Neighborhood Hits	85	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NEM0, Q66GU1, Q9H9C7	Gene names	MCPH1
Domain Architecture
Description	Microcephalin.

INVS_MOUSE
NC score	0.008992 (rank : 277)	θ value	0.813845 (rank : 127)
Query Neighborhood Hits	248	Target Neighborhood Hits	609	Shared Neighborhood Hits	23
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

CAF1A_HUMAN
NC score	0.008879 (rank : 278)	θ value	8.99809 (rank : 232)
Query Neighborhood Hits	248	Target Neighborhood Hits	750	Shared Neighborhood Hits	31
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

HS105_HUMAN
NC score	0.008728 (rank : 279)	θ value	3.0926 (rank : 170)
Query Neighborhood Hits	248	Target Neighborhood Hits	209	Shared Neighborhood Hits	20
SwissProt Accessions	Q92598, O95739, Q5TBM6, Q5TBM8, Q9UPC4	Gene names	HSPH1, HSP105, HSP110, KIAA0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock 110 kDa protein) (Antigen NY- CO-25).

DYH9_HUMAN
NC score	0.008669 (rank : 280)	θ value	1.81305 (rank : 146)
Query Neighborhood Hits	248	Target Neighborhood Hits	291	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NYC9, O95494, Q9NQ28	Gene names	DNAH9, DNAH17L, DNAL1
Domain Architecture
Description	Ciliary dynein heavy chain 9 (Axonemal beta dynein heavy chain 9).

RYR1_HUMAN
NC score	0.008102 (rank : 281)	θ value	8.99809 (rank : 245)
Query Neighborhood Hits	248	Target Neighborhood Hits	303	Shared Neighborhood Hits	19
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

GLUD1_MOUSE
NC score	0.007997 (rank : 282)	θ value	8.99809 (rank : 235)
Query Neighborhood Hits	248	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CIX8	Gene names	Gluld1, Lgs
Domain Architecture	No domain graphic available
Description	Glutamate--ammonia ligase domain-containing protein 1 (Lengsin) (Lens glutamine synthase-like).

HEM1_MOUSE
NC score	0.007972 (rank : 283)	θ value	8.99809 (rank : 236)
Query Neighborhood Hits	248	Target Neighborhood Hits	66	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VC19, Q64453	Gene names	Alas1
Domain Architecture	No domain graphic available
Description	5-aminolevulinate synthase, nonspecific, mitochondrial precursor (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta-aminolevulinate synthase) (Delta-ALA synthetase) (ALAS-H).

U2AFM_HUMAN
NC score	0.007679 (rank : 284)	θ value	5.27518 (rank : 215)
Query Neighborhood Hits	248	Target Neighborhood Hits	577	Shared Neighborhood Hits	21
SwissProt Accessions	Q15696	Gene names	ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (NY-REN-20 antigen).

NUP50_MOUSE
NC score	0.007574 (rank : 285)	θ value	8.99809 (rank : 243)
Query Neighborhood Hits	248	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JIH2, Q9CU02, Q9JK85	Gene names	Nup50, Npap60
Domain Architecture
Description	Nucleoporin 50 kDa (Nuclear pore-associated protein 60 kDa-like).

MK10_MOUSE
NC score	0.007359 (rank : 286)	θ value	8.99809 (rank : 238)
Query Neighborhood Hits	248	Target Neighborhood Hits	849	Shared Neighborhood Hits	16
SwissProt Accessions	Q61831, Q9R0U6	Gene names	Mapk10, Jnk3, Prkm10, Serk2
Domain Architecture
Description	Mitogen-activated protein kinase 10 (EC 2.7.11.24) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3) (MAP kinase p49 3F12).

VGFR2_MOUSE
NC score	0.007338 (rank : 287)	θ value	4.03905 (rank : 197)
Query Neighborhood Hits	248	Target Neighborhood Hits	1089	Shared Neighborhood Hits	17
SwissProt Accessions	P35918	Gene names	Kdr, Flk-1, Flk1
Domain Architecture
Description	Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) (Kinase NYK) (CD309 antigen).

CI039_HUMAN
NC score	0.006568 (rank : 288)	θ value	5.27518 (rank : 203)
Query Neighborhood Hits	248	Target Neighborhood Hits	1171	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

SUHW4_HUMAN
NC score	0.006039 (rank : 289)	θ value	0.279714 (rank : 108)
Query Neighborhood Hits	248	Target Neighborhood Hits	860	Shared Neighborhood Hits	28
SwissProt Accessions	Q6N043, Q6MZM6, Q6N085, Q9H0U5, Q9HCI8, Q9NXS0	Gene names	SUHW4, KIAA1584
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

BRWD1_HUMAN
NC score	0.005121 (rank : 290)	θ value	4.03905 (rank : 184)
Query Neighborhood Hits	248	Target Neighborhood Hits	448	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NSI6, O43721, Q5R2V0, Q5R2V1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1	Gene names	BRWD1, C21orf107, WDR9
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

LIPB2_HUMAN
NC score	0.005090 (rank : 291)	θ value	3.0926 (rank : 171)
Query Neighborhood Hits	248	Target Neighborhood Hits	599	Shared Neighborhood Hits	15
SwissProt Accessions	Q8ND30, O75337, Q8WW26	Gene names	PPFIBP2
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2).

HMG1X_HUMAN
NC score	0.004875 (rank : 292)	θ value	6.88961 (rank : 221)
Query Neighborhood Hits	248	Target Neighborhood Hits	97	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UGV6	Gene names	HMG1L10
Domain Architecture
Description	High mobility group protein 1-like 10 (HMG-1L10).

CAC1E_MOUSE
NC score	0.004392 (rank : 293)	θ value	5.27518 (rank : 201)
Query Neighborhood Hits	248	Target Neighborhood Hits	167	Shared Neighborhood Hits	14
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1E_HUMAN
NC score	0.003851 (rank : 294)	θ value	8.99809 (rank : 231)
Query Neighborhood Hits	248	Target Neighborhood Hits	148	Shared Neighborhood Hits	11
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

DDX21_HUMAN
NC score	0.003575 (rank : 295)	θ value	6.88961 (rank : 219)
Query Neighborhood Hits	248	Target Neighborhood Hits	308	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

NPTX1_MOUSE
NC score	0.003232 (rank : 296)	θ value	8.99809 (rank : 242)
Query Neighborhood Hits	248	Target Neighborhood Hits	67	Shared Neighborhood Hits	2
SwissProt Accessions	Q62443	Gene names	Nptx1
Domain Architecture
Description	Neuronal pentraxin-1 precursor (NP1) (Neuronal pentraxin I) (NP-I).

CYTSA_HUMAN
NC score	0.002911 (rank : 297)	θ value	4.03905 (rank : 187)
Query Neighborhood Hits	248	Target Neighborhood Hits	1138	Shared Neighborhood Hits	33
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

CYTSA_MOUSE
NC score	0.002351 (rank : 298)	θ value	4.03905 (rank : 188)
Query Neighborhood Hits	248	Target Neighborhood Hits	1104	Shared Neighborhood Hits	29
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

SSH1_MOUSE
NC score	0.001898 (rank : 299)	θ value	8.99809 (rank : 247)
Query Neighborhood Hits	248	Target Neighborhood Hits	107	Shared Neighborhood Hits	4
SwissProt Accessions	Q76I79, Q3TDG3, Q69ZM4, Q811E5	Gene names	Ssh1, Kiaa1298, Ssh1l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (mSSH-1L).

DMXL2_HUMAN
NC score	0.001833 (rank : 300)	θ value	8.99809 (rank : 233)
Query Neighborhood Hits	248	Target Neighborhood Hits	374	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TDJ6, O94938	Gene names	DMXL2, KIAA0856
Domain Architecture	No domain graphic available
Description	Protein DmX-like 2 (Rabconnectin-3).

SRPK1_HUMAN
NC score	0.001695 (rank : 301)	θ value	3.0926 (rank : 175)
Query Neighborhood Hits	248	Target Neighborhood Hits	706	Shared Neighborhood Hits	17
SwissProt Accessions	Q96SB4, Q12890, Q5R364, Q5R365, Q8IY12	Gene names	SRPK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK1 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 1) (SR-protein-specific kinase 1) (SFRS protein kinase 1).

ZN592_MOUSE
NC score	0.001357 (rank : 302)	θ value	1.06291 (rank : 135)
Query Neighborhood Hits	248	Target Neighborhood Hits	768	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BHZ4, Q80XM1	Gene names	Znf592, Kiaa0211, Zfp592
Domain Architecture	No domain graphic available
Description	Zinc finger protein 592 (Zfp-592).

SALL3_HUMAN
NC score	-0.000103 (rank : 303)	θ value	8.99809 (rank : 246)
Query Neighborhood Hits	248	Target Neighborhood Hits	1066	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

ZSCA5_HUMAN
NC score	-0.003329 (rank : 304)	θ value	0.47712 (rank : 119)
Query Neighborhood Hits	248	Target Neighborhood Hits	862	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BUG6	Gene names	ZSCAN5, ZNF495
Domain Architecture	No domain graphic available
Description	Zinc finger and SCAN domain-containing protein 5 (Zinc finger protein 495).

GLIS3_HUMAN
NC score	-0.004984 (rank : 305)	θ value	2.36792 (rank : 159)
Query Neighborhood Hits	248	Target Neighborhood Hits	758	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NEA6	Gene names	GLIS3, ZNF515
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3) (Zinc finger protein 515).