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Network neighborhood for query Sequence : PLCD1_MOUSE

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PLCD1_MOUSE
SwissProt Accessions	Q8R3B1	Gene names	Plcd1, Plcd
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PLCD1_HUMAN
θ value	0 (rank : 1)	NC score	0.989088 (rank : 2)
Query Neighborhood Hits	106	Target Neighborhood Hits	93	Shared Neighborhood Hits	73
SwissProt Accessions	P51178	Gene names	PLCD1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

PLCD1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	106	Target Neighborhood Hits	106	Shared Neighborhood Hits	106
SwissProt Accessions	Q8R3B1	Gene names	Plcd1, Plcd
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

PLCB4_HUMAN
θ value	7.93343e-89 (rank : 3)	NC score	0.681046 (rank : 8)
Query Neighborhood Hits	106	Target Neighborhood Hits	658	Shared Neighborhood Hits	27
SwissProt Accessions	Q15147, Q5JYS8, Q5JYT0, Q5JYT4, Q9BQW5, Q9BQW6, Q9BQW8, Q9UJQ2	Gene names	PLCB4
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-4) (PLC-beta-4).

PLCB2_HUMAN
θ value	2.47191e-82 (rank : 4)	NC score	0.775201 (rank : 4)
Query Neighborhood Hits	106	Target Neighborhood Hits	608	Shared Neighborhood Hits	26
SwissProt Accessions	Q00722	Gene names	PLCB2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-2) (PLC-beta-2).

PLCB1_HUMAN
θ value	3.22841e-82 (rank : 5)	NC score	0.759512 (rank : 7)
Query Neighborhood Hits	106	Target Neighborhood Hits	614	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NQ66, O60325, Q5TFF7, Q5TGC9, Q8IV93, Q9BQW2, Q9H4H2, Q9H8H5, Q9NQ65, Q9NQH9, Q9NTH4, Q9UJP6, Q9UM26	Gene names	PLCB1, KIAA0581
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

PLCB1_MOUSE
θ value	1.2268e-81 (rank : 6)	NC score	0.770181 (rank : 5)
Query Neighborhood Hits	106	Target Neighborhood Hits	531	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z1B3, Q62075, Q8K5A5, Q8K5A6, Q9Z0E5, Q9Z2T5	Gene names	Plcb1, Plcb
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

PLCG2_HUMAN
θ value	2.32439e-64 (rank : 7)	NC score	0.632263 (rank : 9)
Query Neighborhood Hits	106	Target Neighborhood Hits	280	Shared Neighborhood Hits	25
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

PLCG1_MOUSE
θ value	9.78833e-55 (rank : 8)	NC score	0.618546 (rank : 11)
Query Neighborhood Hits	106	Target Neighborhood Hits	314	Shared Neighborhood Hits	28
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLCG1_HUMAN
θ value	1.66964e-54 (rank : 9)	NC score	0.623952 (rank : 10)
Query Neighborhood Hits	106	Target Neighborhood Hits	293	Shared Neighborhood Hits	28
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLCB3_HUMAN
θ value	8.87376e-48 (rank : 10)	NC score	0.766409 (rank : 6)
Query Neighborhood Hits	106	Target Neighborhood Hits	445	Shared Neighborhood Hits	22
SwissProt Accessions	Q01970	Gene names	PLCB3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

PLCB3_MOUSE
θ value	2.58187e-47 (rank : 11)	NC score	0.794116 (rank : 3)
Query Neighborhood Hits	106	Target Neighborhood Hits	344	Shared Neighborhood Hits	17
SwissProt Accessions	P51432	Gene names	Plcb3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

SYT1_HUMAN
θ value	0.00020696 (rank : 12)	NC score	0.145419 (rank : 14)
Query Neighborhood Hits	106	Target Neighborhood Hits	150	Shared Neighborhood Hits	55
SwissProt Accessions	P21579	Gene names	SYT1, SYT
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT1_MOUSE
θ value	0.00020696 (rank : 13)	NC score	0.145410 (rank : 15)
Query Neighborhood Hits	106	Target Neighborhood Hits	150	Shared Neighborhood Hits	55
SwissProt Accessions	P46096	Gene names	Syt1
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

CPNE6_HUMAN
θ value	0.000461057 (rank : 14)	NC score	0.102919 (rank : 45)
Query Neighborhood Hits	106	Target Neighborhood Hits	85	Shared Neighborhood Hits	46
SwissProt Accessions	O95741, Q53HA6, Q8WVG1	Gene names	CPNE6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

CPNE6_MOUSE
θ value	0.000786445 (rank : 15)	NC score	0.105769 (rank : 41)
Query Neighborhood Hits	106	Target Neighborhood Hits	87	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z140	Gene names	Cpne6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

CALU_MOUSE
θ value	0.00665767 (rank : 16)	NC score	0.069036 (rank : 96)
Query Neighborhood Hits	106	Target Neighborhood Hits	113	Shared Neighborhood Hits	8
SwissProt Accessions	O35887	Gene names	Calu
Domain Architecture
Description	Calumenin precursor (Crocalbin).

RASL2_HUMAN
θ value	0.00665767 (rank : 17)	NC score	0.123710 (rank : 29)
Query Neighborhood Hits	106	Target Neighborhood Hits	161	Shared Neighborhood Hits	55
SwissProt Accessions	O43374, O60286, Q86UW3, Q96QU0	Gene names	RASA4, CAPRI, GAPL, KIAA0538
Domain Architecture
Description	Ras GTPase-activating protein 4 (RasGAP-activating-like protein 2) (Calcium-promoted Ras inactivator).

NED4L_HUMAN
θ value	0.00869519 (rank : 18)	NC score	0.101702 (rank : 47)
Query Neighborhood Hits	106	Target Neighborhood Hits	238	Shared Neighborhood Hits	57
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NED4L_MOUSE
θ value	0.00869519 (rank : 19)	NC score	0.100915 (rank : 48)
Query Neighborhood Hits	106	Target Neighborhood Hits	231	Shared Neighborhood Hits	57
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

CALU_HUMAN
θ value	0.0113563 (rank : 20)	NC score	0.065862 (rank : 101)
Query Neighborhood Hits	106	Target Neighborhood Hits	114	Shared Neighborhood Hits	7
SwissProt Accessions	O43852, O60456, Q6FHB9, Q96RL3, Q9NR43	Gene names	CALU
Domain Architecture
Description	Calumenin precursor (Crocalbin) (IEF SSP 9302).

SYT5_HUMAN
θ value	0.0113563 (rank : 21)	NC score	0.138082 (rank : 18)
Query Neighborhood Hits	106	Target Neighborhood Hits	138	Shared Neighborhood Hits	55
SwissProt Accessions	O00445, Q86X72	Gene names	SYT5
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV).

AKAP9_HUMAN
θ value	0.0148317 (rank : 22)	NC score	0.049414 (rank : 155)
Query Neighborhood Hits	106	Target Neighborhood Hits	1710	Shared Neighborhood Hits	30
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

SYT5_MOUSE
θ value	0.0252991 (rank : 23)	NC score	0.137292 (rank : 19)
Query Neighborhood Hits	106	Target Neighborhood Hits	140	Shared Neighborhood Hits	56
SwissProt Accessions	Q9R0N5	Gene names	Syt5, Syt9
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV) (Synaptotagmin IX).

SYT2_HUMAN
θ value	0.0330416 (rank : 24)	NC score	0.133002 (rank : 23)
Query Neighborhood Hits	106	Target Neighborhood Hits	142	Shared Neighborhood Hits	55
SwissProt Accessions	Q8N9I0, Q496K5, Q8NBE5	Gene names	SYT2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT2_MOUSE
θ value	0.0330416 (rank : 25)	NC score	0.133761 (rank : 22)
Query Neighborhood Hits	106	Target Neighborhood Hits	143	Shared Neighborhood Hits	55
SwissProt Accessions	P46097, Q8R0E1	Gene names	Syt2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

MYOF_HUMAN
θ value	0.0563607 (rank : 26)	NC score	0.112581 (rank : 36)
Query Neighborhood Hits	106	Target Neighborhood Hits	147	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NZM1, Q9HBU3, Q9NZM0, Q9ULL3, Q9Y4U4	Gene names	FER1L3, KIAA1207, MYOF
Domain Architecture
Description	Myoferlin (Fer-1-like protein 3).

NEDD4_MOUSE
θ value	0.0563607 (rank : 27)	NC score	0.087969 (rank : 61)
Query Neighborhood Hits	106	Target Neighborhood Hits	212	Shared Neighborhood Hits	53
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

DYSF_MOUSE
θ value	0.0961366 (rank : 28)	NC score	0.102963 (rank : 44)
Query Neighborhood Hits	106	Target Neighborhood Hits	162	Shared Neighborhood Hits	53
SwissProt Accessions	Q9ESD7, Q9QXC0	Gene names	Dysf, Fer1l1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

KPCA_MOUSE
θ value	0.0961366 (rank : 29)	NC score	0.039970 (rank : 159)
Query Neighborhood Hits	106	Target Neighborhood Hits	1067	Shared Neighborhood Hits	60
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

SYT7_MOUSE
θ value	0.125558 (rank : 30)	NC score	0.137150 (rank : 20)
Query Neighborhood Hits	106	Target Neighborhood Hits	137	Shared Neighborhood Hits	55
SwissProt Accessions	Q9R0N7	Gene names	Syt7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

AB2BP_MOUSE
θ value	0.163984 (rank : 31)	NC score	0.092303 (rank : 54)
Query Neighborhood Hits	106	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D6J4, Q3TYZ9, Q9ESR0	Gene names	Apba2bp, Xb51
Domain Architecture
Description	Amyloid beta A4 protein-binding family A member 2-binding protein (X11L-binding protein 51) (mXB51).

NEDD4_HUMAN
θ value	0.163984 (rank : 32)	NC score	0.086366 (rank : 62)
Query Neighborhood Hits	106	Target Neighborhood Hits	214	Shared Neighborhood Hits	53
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

TEX15_HUMAN
θ value	0.163984 (rank : 33)	NC score	0.051570 (rank : 146)
Query Neighborhood Hits	106	Target Neighborhood Hits	174	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BXT5	Gene names	TEX15
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 15 protein.

K0528_HUMAN
θ value	0.21417 (rank : 34)	NC score	0.130691 (rank : 24)
Query Neighborhood Hits	106	Target Neighborhood Hits	96	Shared Neighborhood Hits	47
SwissProt Accessions	Q86YS7, O60280, Q7Z619, Q86SU3	Gene names	KIAA0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

K0528_MOUSE
θ value	0.21417 (rank : 35)	NC score	0.130481 (rank : 25)
Query Neighborhood Hits	106	Target Neighborhood Hits	102	Shared Neighborhood Hits	47
SwissProt Accessions	Q7TPS5, Q3TQY6, Q6A052, Q80VA1, Q8C0U3, Q8CID5, Q9CS85	Gene names	Kiaa0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

KPCA_HUMAN
θ value	0.21417 (rank : 36)	NC score	0.038150 (rank : 162)
Query Neighborhood Hits	106	Target Neighborhood Hits	1070	Shared Neighborhood Hits	59
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

SYT7_HUMAN
θ value	0.21417 (rank : 37)	NC score	0.136542 (rank : 21)
Query Neighborhood Hits	106	Target Neighborhood Hits	137	Shared Neighborhood Hits	53
SwissProt Accessions	O43581	Gene names	SYT7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

KPCG_MOUSE
θ value	0.279714 (rank : 38)	NC score	0.042138 (rank : 157)
Query Neighborhood Hits	106	Target Neighborhood Hits	1123	Shared Neighborhood Hits	58
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

CPNE7_HUMAN
θ value	0.365318 (rank : 39)	NC score	0.082273 (rank : 70)
Query Neighborhood Hits	106	Target Neighborhood Hits	92	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UBL6	Gene names	CPNE7
Domain Architecture
Description	Copine-7 (Copine VII).

DOC2B_MOUSE
θ value	0.365318 (rank : 40)	NC score	0.144179 (rank : 16)
Query Neighborhood Hits	106	Target Neighborhood Hits	169	Shared Neighborhood Hits	58
SwissProt Accessions	P70169, Q6NXK3	Gene names	Doc2b
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

AB2BP_HUMAN
θ value	0.47712 (rank : 41)	NC score	0.085259 (rank : 64)
Query Neighborhood Hits	106	Target Neighborhood Hits	35	Shared Neighborhood Hits	6
SwissProt Accessions	Q96P71, Q5JWF6, Q5JWF7, Q86VV1, Q9H433, Q9H8G8, Q9HBW7, Q9HCQ9	Gene names	APBA2BP, NECAB3, NIP1, XB51
Domain Architecture
Description	Amyloid beta A4 protein-binding family A member 2-binding protein (Neuronal calcium-binding protein 3) (NECAB 3) (X11L-binding protein 51) (Nek2-interacting protein 1).

DOC2A_MOUSE
θ value	0.47712 (rank : 42)	NC score	0.154175 (rank : 12)
Query Neighborhood Hits	106	Target Neighborhood Hits	140	Shared Neighborhood Hits	60
SwissProt Accessions	Q7TNF0	Gene names	Doc2a
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha).

KNTC2_MOUSE
θ value	0.47712 (rank : 43)	NC score	0.035313 (rank : 165)
Query Neighborhood Hits	106	Target Neighborhood Hits	692	Shared Neighborhood Hits	19
SwissProt Accessions	Q9D0F1, Q3TQT6, Q3UWM5, Q99P70	Gene names	Kntc2, Hec1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (Kinetochore-associated protein 2).

KPCG_HUMAN
θ value	0.47712 (rank : 44)	NC score	0.041722 (rank : 158)
Query Neighborhood Hits	106	Target Neighborhood Hits	1126	Shared Neighborhood Hits	58
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

MYH2_HUMAN
θ value	0.47712 (rank : 45)	NC score	0.025021 (rank : 168)
Query Neighborhood Hits	106	Target Neighborhood Hits	1491	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

SYT3_HUMAN
θ value	0.47712 (rank : 46)	NC score	0.123866 (rank : 28)
Query Neighborhood Hits	106	Target Neighborhood Hits	145	Shared Neighborhood Hits	55
SwissProt Accessions	Q9BQG1, Q8N5Z1, Q8N640	Gene names	SYT3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

DOC2B_HUMAN
θ value	0.62314 (rank : 47)	NC score	0.143814 (rank : 17)
Query Neighborhood Hits	106	Target Neighborhood Hits	150	Shared Neighborhood Hits	58
SwissProt Accessions	Q14184	Gene names	DOC2B
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

SEGN_MOUSE
θ value	0.62314 (rank : 48)	NC score	0.063188 (rank : 105)
Query Neighborhood Hits	106	Target Neighborhood Hits	101	Shared Neighborhood Hits	8
SwissProt Accessions	Q91WD9	Gene names	Scgn
Domain Architecture
Description	Secretagogin.

SYT3_MOUSE
θ value	0.62314 (rank : 49)	NC score	0.123452 (rank : 30)
Query Neighborhood Hits	106	Target Neighborhood Hits	147	Shared Neighborhood Hits	55
SwissProt Accessions	O35681, P97791, Q80WV1	Gene names	Syt3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

CU013_HUMAN
θ value	0.813845 (rank : 50)	NC score	0.053877 (rank : 135)
Query Neighborhood Hits	106	Target Neighborhood Hits	405	Shared Neighborhood Hits	18
SwissProt Accessions	O95447	Gene names	C21orf13
Domain Architecture
Description	Protein C21orf13.

DOC2A_HUMAN
θ value	1.06291 (rank : 51)	NC score	0.149092 (rank : 13)
Query Neighborhood Hits	106	Target Neighborhood Hits	144	Shared Neighborhood Hits	59
SwissProt Accessions	Q14183, Q6P4G4, Q7Z5G0, Q8IVX0	Gene names	DOC2A
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha) (Doc2).

KTN1_HUMAN
θ value	1.06291 (rank : 52)	NC score	0.036501 (rank : 164)
Query Neighborhood Hits	106	Target Neighborhood Hits	1197	Shared Neighborhood Hits	22
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

MYH1_HUMAN
θ value	1.06291 (rank : 53)	NC score	0.025821 (rank : 167)
Query Neighborhood Hits	106	Target Neighborhood Hits	1478	Shared Neighborhood Hits	24
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

SYT11_HUMAN
θ value	1.06291 (rank : 54)	NC score	0.124460 (rank : 26)
Query Neighborhood Hits	106	Target Neighborhood Hits	113	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BT88, Q14998, Q68CT5, Q8IXU3, Q96SU2	Gene names	SYT11, KIAA0080
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

SYT11_MOUSE
θ value	1.06291 (rank : 55)	NC score	0.124329 (rank : 27)
Query Neighborhood Hits	106	Target Neighborhood Hits	116	Shared Neighborhood Hits	48
SwissProt Accessions	Q9R0N3	Gene names	Syt11
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

TEC_HUMAN
θ value	1.06291 (rank : 56)	NC score	0.017104 (rank : 180)
Query Neighborhood Hits	106	Target Neighborhood Hits	1006	Shared Neighborhood Hits	18
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

BAIP3_HUMAN
θ value	1.38821 (rank : 57)	NC score	0.102759 (rank : 46)
Query Neighborhood Hits	106	Target Neighborhood Hits	108	Shared Neighborhood Hits	47
SwissProt Accessions	O94812, O94839, Q2M226, Q658J2, Q76N05, Q96RZ3, Q9UJK1	Gene names	BAIAP3, KIAA0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

CCD11_HUMAN
θ value	1.38821 (rank : 58)	NC score	0.047034 (rank : 156)
Query Neighborhood Hits	106	Target Neighborhood Hits	822	Shared Neighborhood Hits	23
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

MCM8_HUMAN
θ value	1.38821 (rank : 59)	NC score	0.022701 (rank : 171)
Query Neighborhood Hits	106	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UJA3, Q495R4, Q495R7, Q86US4, Q969I5	Gene names	MCM8, C20orf154
Domain Architecture
Description	DNA replication licensing factor MCM8 (Minichromosome maintenance 8).

TF2LY_HUMAN
θ value	1.38821 (rank : 60)	NC score	0.020190 (rank : 174)
Query Neighborhood Hits	106	Target Neighborhood Hits	90	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IUE0	Gene names	TGIF2LY, TGIFLY
Domain Architecture
Description	Homeobox protein TGIF2LY (TGFB-induced factor 2-like protein, Y- linked) (TGF(beta)induced transcription factor 2-like protein) (TGIF- like on the Y).

ARNT2_HUMAN
θ value	1.81305 (rank : 61)	NC score	0.015555 (rank : 184)
Query Neighborhood Hits	106	Target Neighborhood Hits	109	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT2_MOUSE
θ value	1.81305 (rank : 62)	NC score	0.015514 (rank : 185)
Query Neighborhood Hits	106	Target Neighborhood Hits	115	Shared Neighborhood Hits	3
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

KPCB_HUMAN
θ value	1.81305 (rank : 63)	NC score	0.038322 (rank : 161)
Query Neighborhood Hits	106	Target Neighborhood Hits	1121	Shared Neighborhood Hits	60
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCB_MOUSE
θ value	1.81305 (rank : 64)	NC score	0.038766 (rank : 160)
Query Neighborhood Hits	106	Target Neighborhood Hits	1117	Shared Neighborhood Hits	60
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

TEC_MOUSE
θ value	1.81305 (rank : 65)	NC score	0.016550 (rank : 182)
Query Neighborhood Hits	106	Target Neighborhood Hits	1006	Shared Neighborhood Hits	18
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

KTN1_MOUSE
θ value	2.36792 (rank : 66)	NC score	0.037256 (rank : 163)
Query Neighborhood Hits	106	Target Neighborhood Hits	1324	Shared Neighborhood Hits	24
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

SEGN_HUMAN
θ value	2.36792 (rank : 67)	NC score	0.051453 (rank : 148)
Query Neighborhood Hits	106	Target Neighborhood Hits	96	Shared Neighborhood Hits	6
SwissProt Accessions	O76038, Q5VV44, Q96QV7, Q9UJF6	Gene names	SCGN, SECRET
Domain Architecture
Description	Secretagogin.

BAIP3_MOUSE
θ value	3.0926 (rank : 68)	NC score	0.099000 (rank : 49)
Query Neighborhood Hits	106	Target Neighborhood Hits	112	Shared Neighborhood Hits	50
SwissProt Accessions	Q80TT2, Q6RUT4	Gene names	Baiap3, Gm937, Kiaa0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

CPNE4_HUMAN
θ value	3.0926 (rank : 69)	NC score	0.062937 (rank : 106)
Query Neighborhood Hits	106	Target Neighborhood Hits	70	Shared Neighborhood Hits	38
SwissProt Accessions	Q96A23, Q8TEX1	Gene names	CPNE4
Domain Architecture
Description	Copine-4 (Copine IV) (Copine-8).

CPNE4_MOUSE
θ value	3.0926 (rank : 70)	NC score	0.062761 (rank : 108)
Query Neighborhood Hits	106	Target Neighborhood Hits	67	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BLR2	Gene names	Cpne4
Domain Architecture	No domain graphic available
Description	Copine-4 (Copine IV).

HAP1_HUMAN
θ value	3.0926 (rank : 71)	NC score	0.018003 (rank : 177)
Query Neighborhood Hits	106	Target Neighborhood Hits	606	Shared Neighborhood Hits	18
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

MYH1_MOUSE
θ value	3.0926 (rank : 72)	NC score	0.022524 (rank : 172)
Query Neighborhood Hits	106	Target Neighborhood Hits	1461	Shared Neighborhood Hits	24
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

RP3A_HUMAN
θ value	3.0926 (rank : 73)	NC score	0.118224 (rank : 32)
Query Neighborhood Hits	106	Target Neighborhood Hits	305	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

RP3A_MOUSE
θ value	3.0926 (rank : 74)	NC score	0.118392 (rank : 31)
Query Neighborhood Hits	106	Target Neighborhood Hits	510	Shared Neighborhood Hits	54
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SYNE1_HUMAN
θ value	3.0926 (rank : 75)	NC score	0.030622 (rank : 166)
Query Neighborhood Hits	106	Target Neighborhood Hits	1484	Shared Neighborhood Hits	30
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

SYT10_HUMAN
θ value	3.0926 (rank : 76)	NC score	0.109270 (rank : 39)
Query Neighborhood Hits	106	Target Neighborhood Hits	134	Shared Neighborhood Hits	54
SwissProt Accessions	Q6XYQ8	Gene names	SYT10
Domain Architecture	No domain graphic available
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

DUOX1_HUMAN
θ value	4.03905 (rank : 77)	NC score	0.007606 (rank : 193)
Query Neighborhood Hits	106	Target Neighborhood Hits	172	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NRD9, Q6ZMB3, Q6ZR09, Q9NZC1	Gene names	DUOX1, DUOX, LNOX1, THOX1
Domain Architecture	No domain graphic available
Description	Dual oxidase 1 precursor (EC 1.6.3.1) (EC 1.11.1.-) (NADPH thyroid oxidase 1) (Thyroid oxidase 1) (Large NOX 1) (Long NOX 1).

MPDZ_HUMAN
θ value	4.03905 (rank : 78)	NC score	0.007966 (rank : 191)
Query Neighborhood Hits	106	Target Neighborhood Hits	261	Shared Neighborhood Hits	4
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

NCOR2_HUMAN
θ value	4.03905 (rank : 79)	NC score	0.018339 (rank : 176)
Query Neighborhood Hits	106	Target Neighborhood Hits	870	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

RASL1_MOUSE
θ value	4.03905 (rank : 80)	NC score	0.092563 (rank : 53)
Query Neighborhood Hits	106	Target Neighborhood Hits	148	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Z268	Gene names	Rasal1, Rasal
Domain Architecture
Description	RasGAP-activating-like protein 1.

ROCK2_HUMAN
θ value	4.03905 (rank : 81)	NC score	0.017941 (rank : 178)
Query Neighborhood Hits	106	Target Neighborhood Hits	2073	Shared Neighborhood Hits	33
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

TAF3_MOUSE
θ value	4.03905 (rank : 82)	NC score	0.017032 (rank : 181)
Query Neighborhood Hits	106	Target Neighborhood Hits	463	Shared Neighborhood Hits	8
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

DUS2L_MOUSE
θ value	5.27518 (rank : 83)	NC score	0.011593 (rank : 189)
Query Neighborhood Hits	106	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D7B1, Q6PDX2	Gene names	Dus2l
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 2-like (EC 1.-.-.-).

EFHC1_HUMAN
θ value	5.27518 (rank : 84)	NC score	0.017939 (rank : 179)
Query Neighborhood Hits	106	Target Neighborhood Hits	61	Shared Neighborhood Hits	5
SwissProt Accessions	Q5JVL4, Q5XKM4, Q6E1U7, Q6E1U8, Q8WUL2, Q9NVW6	Gene names	EFHC1
Domain Architecture	No domain graphic available
Description	EF-hand domain-containing protein 1.

FA62A_MOUSE
θ value	5.27518 (rank : 85)	NC score	0.091366 (rank : 58)
Query Neighborhood Hits	106	Target Neighborhood Hits	155	Shared Neighborhood Hits	54
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

ITSN1_HUMAN
θ value	5.27518 (rank : 86)	NC score	0.076165 (rank : 78)
Query Neighborhood Hits	106	Target Neighborhood Hits	1757	Shared Neighborhood Hits	78
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN1_MOUSE
θ value	5.27518 (rank : 87)	NC score	0.072138 (rank : 87)
Query Neighborhood Hits	106	Target Neighborhood Hits	1669	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

KNTC2_HUMAN
θ value	5.27518 (rank : 88)	NC score	0.022713 (rank : 170)
Query Neighborhood Hits	106	Target Neighborhood Hits	673	Shared Neighborhood Hits	18
SwissProt Accessions	O14777, Q6PJX2	Gene names	KNTC2, HEC, HEC1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cancer protein) (Retinoblastoma-associated protein HEC).

MPDZ_MOUSE
θ value	5.27518 (rank : 89)	NC score	0.007617 (rank : 192)
Query Neighborhood Hits	106	Target Neighborhood Hits	298	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

RASF8_HUMAN
θ value	5.27518 (rank : 90)	NC score	0.019779 (rank : 175)
Query Neighborhood Hits	106	Target Neighborhood Hits	469	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NHQ8, O95647, Q5SCI2, Q76KB6	Gene names	RASSF8, C12orf2
Domain Architecture
Description	Ras association domain-containing protein 8 (Carcinoma-associated protein HOJ-1).

CYLD_HUMAN
θ value	6.88961 (rank : 91)	NC score	0.022137 (rank : 173)
Query Neighborhood Hits	106	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NQC7, O94934, Q7L3N6, Q96EH0, Q9NZX9	Gene names	CYLD, CYLD1, KIAA0849
Domain Architecture	No domain graphic available
Description	Probable ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.1.2.15) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD) (Deubiquitinating enzyme CYLD).

CYLD_MOUSE
θ value	6.88961 (rank : 92)	NC score	0.023246 (rank : 169)
Query Neighborhood Hits	106	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q80TQ2, Q80VB3, Q8BXZ3, Q8BYL9, Q8CGB0	Gene names	Cyld, Cyld1, Kiaa0849
Domain Architecture	No domain graphic available
Description	Probable ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.1.2.15) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD) (Deubiquitinating enzyme CYLD).

DYSF_HUMAN
θ value	6.88961 (rank : 93)	NC score	0.084278 (rank : 67)
Query Neighborhood Hits	106	Target Neighborhood Hits	170	Shared Neighborhood Hits	56
SwissProt Accessions	O75923, O75696, Q9UEN7	Gene names	DYSF, FER1L1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

LETM1_MOUSE
θ value	6.88961 (rank : 94)	NC score	0.014086 (rank : 186)
Query Neighborhood Hits	106	Target Neighborhood Hits	240	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z2I0, Q5PQC5, Q7TMK8, Q80ZX6, Q8CGJ3, Q8K5E5	Gene names	Letm1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

MACF1_MOUSE
θ value	6.88961 (rank : 95)	NC score	0.013868 (rank : 187)
Query Neighborhood Hits	106	Target Neighborhood Hits	1313	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

PLSI_HUMAN
θ value	6.88961 (rank : 96)	NC score	0.016231 (rank : 183)
Query Neighborhood Hits	106	Target Neighborhood Hits	209	Shared Neighborhood Hits	14
SwissProt Accessions	Q14651	Gene names	PLS1
Domain Architecture
Description	Plastin-1 (I-plastin) (Intestine-specific plastin).

REV1_MOUSE
θ value	6.88961 (rank : 97)	NC score	0.009103 (rank : 190)
Query Neighborhood Hits	106	Target Neighborhood Hits	67	Shared Neighborhood Hits	2
SwissProt Accessions	Q920Q2, Q9QXV2	Gene names	Rev1l, Rev1
Domain Architecture	No domain graphic available
Description	DNA repair protein REV1 (EC 2.7.7.-) (Rev1-like terminal deoxycytidyl transferase).

S10A5_MOUSE
θ value	6.88961 (rank : 98)	NC score	0.007098 (rank : 194)
Query Neighborhood Hits	106	Target Neighborhood Hits	54	Shared Neighborhood Hits	2
SwissProt Accessions	P63084, O88945, P82540	Gene names	S100a5, S100d
Domain Architecture	No domain graphic available
Description	Protein S100-A5 (S100 calcium-binding protein A5) (Protein S-100D).

SYT9_HUMAN
θ value	6.88961 (rank : 99)	NC score	0.113309 (rank : 34)
Query Neighborhood Hits	106	Target Neighborhood Hits	144	Shared Neighborhood Hits	56
SwissProt Accessions	Q86SS6	Gene names	SYT9
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX).

CPNE5_HUMAN
θ value	8.99809 (rank : 100)	NC score	0.070579 (rank : 91)
Query Neighborhood Hits	106	Target Neighborhood Hits	88	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HCH3	Gene names	CPNE5, KIAA1599
Domain Architecture
Description	Copine-5 (Copine V).

CPNE5_MOUSE
θ value	8.99809 (rank : 101)	NC score	0.070722 (rank : 90)
Query Neighborhood Hits	106	Target Neighborhood Hits	86	Shared Neighborhood Hits	48
SwissProt Accessions	Q8JZW4	Gene names	Cpne5
Domain Architecture
Description	Copine-5 (Copine V).

DOC2G_MOUSE
θ value	8.99809 (rank : 102)	NC score	0.112923 (rank : 35)
Query Neighborhood Hits	106	Target Neighborhood Hits	125	Shared Neighborhood Hits	49
SwissProt Accessions	Q9ESN1, Q6P8R8	Gene names	Doc2g
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein gamma (Doc2-gamma).

EFHC1_MOUSE
θ value	8.99809 (rank : 103)	NC score	0.012829 (rank : 188)
Query Neighborhood Hits	106	Target Neighborhood Hits	65	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D9T8	Gene names	Efhc1
Domain Architecture	No domain graphic available
Description	EF-hand domain-containing protein 1.

FA62A_HUMAN
θ value	8.99809 (rank : 104)	NC score	0.091783 (rank : 57)
Query Neighborhood Hits	106	Target Neighborhood Hits	168	Shared Neighborhood Hits	55
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

SYT4_HUMAN
θ value	8.99809 (rank : 105)	NC score	0.114014 (rank : 33)
Query Neighborhood Hits	106	Target Neighborhood Hits	121	Shared Neighborhood Hits	51
SwissProt Accessions	Q9H2B2, Q9P2K4	Gene names	SYT4, KIAA1342
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

SYT9_MOUSE
θ value	8.99809 (rank : 106)	NC score	0.112342 (rank : 37)
Query Neighborhood Hits	106	Target Neighborhood Hits	148	Shared Neighborhood Hits	56
SwissProt Accessions	Q9R0N9, Q8C280	Gene names	Syt9, Syt5
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX) (Synaptotagmin V).

APS_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.053765 (rank : 136)
Query Neighborhood Hits	106	Target Neighborhood Hits	162	Shared Neighborhood Hits	3
SwissProt Accessions	O14492	Gene names	APS
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

CAF1A_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.056047 (rank : 120)
Query Neighborhood Hits	106	Target Neighborhood Hits	750	Shared Neighborhood Hits	18
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CCD19_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.054122 (rank : 132)
Query Neighborhood Hits	106	Target Neighborhood Hits	639	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

CCD21_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.051866 (rank : 145)
Query Neighborhood Hits	106	Target Neighborhood Hits	1228	Shared Neighborhood Hits	26
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CCD45_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.051928 (rank : 143)
Query Neighborhood Hits	106	Target Neighborhood Hits	663	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

CCD46_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.053243 (rank : 138)
Query Neighborhood Hits	106	Target Neighborhood Hits	1430	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

CCD46_MOUSE
θ value	θ > 10 (rank : 113)	NC score	0.050465 (rank : 153)
Query Neighborhood Hits	106	Target Neighborhood Hits	1405	Shared Neighborhood Hits	26
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

CPNE1_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.061752 (rank : 109)
Query Neighborhood Hits	106	Target Neighborhood Hits	70	Shared Neighborhood Hits	43
SwissProt Accessions	Q99829, Q6IBL3, Q9H243, Q9NTZ7	Gene names	CPNE1, CPN1
Domain Architecture
Description	Copine-1 (Copine I).

CPNE1_MOUSE
θ value	θ > 10 (rank : 115)	NC score	0.066845 (rank : 98)
Query Neighborhood Hits	106	Target Neighborhood Hits	83	Shared Neighborhood Hits	45
SwissProt Accessions	Q8C166, Q925K4, Q925K5	Gene names	Cpne1
Domain Architecture
Description	Copine-1 (Copine I).

CPNE2_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.073911 (rank : 82)
Query Neighborhood Hits	106	Target Neighborhood Hits	75	Shared Neighborhood Hits	46
SwissProt Accessions	Q96FN4, Q68D19, Q86XP9	Gene names	CPNE2
Domain Architecture
Description	Copine-2 (Copine II).

CPNE2_MOUSE
θ value	θ > 10 (rank : 117)	NC score	0.072700 (rank : 86)
Query Neighborhood Hits	106	Target Neighborhood Hits	82	Shared Neighborhood Hits	46
SwissProt Accessions	P59108, Q8K1D7	Gene names	Cpne2
Domain Architecture
Description	Copine-2 (Copine II).

CPNE3_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.072708 (rank : 85)
Query Neighborhood Hits	106	Target Neighborhood Hits	90	Shared Neighborhood Hits	45
SwissProt Accessions	O75131, Q8IYA1	Gene names	CPNE3, CPN3, KIAA0636
Domain Architecture
Description	Copine-3 (Copine III).

CPNE3_MOUSE
θ value	θ > 10 (rank : 119)	NC score	0.073748 (rank : 83)
Query Neighborhood Hits	106	Target Neighborhood Hits	90	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BT60, Q5CZX9, Q5DU22	Gene names	Cpne3, Kiaa0636
Domain Architecture
Description	Copine-3 (Copine III).

CPNE8_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.070302 (rank : 92)
Query Neighborhood Hits	106	Target Neighborhood Hits	86	Shared Neighborhood Hits	46
SwissProt Accessions	Q86YQ8, Q2TB41	Gene names	CPNE8
Domain Architecture
Description	Copine-8 (Copine VIII).

CPNE8_MOUSE
θ value	θ > 10 (rank : 121)	NC score	0.067571 (rank : 97)
Query Neighborhood Hits	106	Target Neighborhood Hits	85	Shared Neighborhood Hits	45
SwissProt Accessions	Q9DC53, Q9CUZ8	Gene names	Cpne8
Domain Architecture
Description	Copine-8 (Copine VIII).

CRKL_MOUSE
θ value	θ > 10 (rank : 122)	NC score	0.050609 (rank : 152)
Query Neighborhood Hits	106	Target Neighborhood Hits	307	Shared Neighborhood Hits	7
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

CRK_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.055406 (rank : 125)
Query Neighborhood Hits	106	Target Neighborhood Hits	308	Shared Neighborhood Hits	7
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CRK_MOUSE
θ value	θ > 10 (rank : 124)	NC score	0.054270 (rank : 131)
Query Neighborhood Hits	106	Target Neighborhood Hits	314	Shared Neighborhood Hits	7
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

DAPP1_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.061088 (rank : 110)
Query Neighborhood Hits	106	Target Neighborhood Hits	227	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_MOUSE
θ value	θ > 10 (rank : 126)	NC score	0.066283 (rank : 99)
Query Neighborhood Hits	106	Target Neighborhood Hits	225	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DBNL_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.051979 (rank : 141)
Query Neighborhood Hits	106	Target Neighborhood Hits	244	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

GRAP_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.054986 (rank : 128)
Query Neighborhood Hits	106	Target Neighborhood Hits	307	Shared Neighborhood Hits	7
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

GRAP_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.056548 (rank : 116)
Query Neighborhood Hits	106	Target Neighborhood Hits	309	Shared Neighborhood Hits	7
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

GRB2_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.055216 (rank : 126)
Query Neighborhood Hits	106	Target Neighborhood Hits	310	Shared Neighborhood Hits	7
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
θ value	θ > 10 (rank : 131)	NC score	0.056276 (rank : 118)
Query Neighborhood Hits	106	Target Neighborhood Hits	312	Shared Neighborhood Hits	7
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

HSH2D_MOUSE
θ value	θ > 10 (rank : 132)	NC score	0.053188 (rank : 139)
Query Neighborhood Hits	106	Target Neighborhood Hits	124	Shared Neighborhood Hits	3
SwissProt Accessions	Q6VYH9, Q52KL3	Gene names	Hsh2d, Alx
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

ITSN2_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.071604 (rank : 88)
Query Neighborhood Hits	106	Target Neighborhood Hits	1173	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

ITSN2_MOUSE
θ value	θ > 10 (rank : 134)	NC score	0.076893 (rank : 76)
Query Neighborhood Hits	106	Target Neighborhood Hits	1371	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

LCP2_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.056965 (rank : 114)
Query Neighborhood Hits	106	Target Neighborhood Hits	531	Shared Neighborhood Hits	6
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

LCP2_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.074913 (rank : 80)
Query Neighborhood Hits	106	Target Neighborhood Hits	177	Shared Neighborhood Hits	5
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

MAP1B_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.050943 (rank : 151)
Query Neighborhood Hits	106	Target Neighborhood Hits	903	Shared Neighborhood Hits	17
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

NCK1_HUMAN
θ value	θ > 10 (rank : 138)	NC score	0.051435 (rank : 149)
Query Neighborhood Hits	106	Target Neighborhood Hits	312	Shared Neighborhood Hits	7
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

OTOF_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.069899 (rank : 93)
Query Neighborhood Hits	106	Target Neighborhood Hits	168	Shared Neighborhood Hits	53
SwissProt Accessions	Q9HC10, Q9HC08, Q9HC09, Q9Y650	Gene names	OTOF, FER1L2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

OTOF_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.069049 (rank : 95)
Query Neighborhood Hits	106	Target Neighborhood Hits	196	Shared Neighborhood Hits	53
SwissProt Accessions	Q9ESF1, Q9ESF2	Gene names	Otof, Fer1l2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

P55G_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.058496 (rank : 111)
Query Neighborhood Hits	106	Target Neighborhood Hits	451	Shared Neighborhood Hits	18
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P55G_MOUSE
θ value	θ > 10 (rank : 142)	NC score	0.054828 (rank : 129)
Query Neighborhood Hits	106	Target Neighborhood Hits	401	Shared Neighborhood Hits	16
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P85B_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.053945 (rank : 134)
Query Neighborhood Hits	106	Target Neighborhood Hits	543	Shared Neighborhood Hits	19
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

P85B_MOUSE
θ value	θ > 10 (rank : 144)	NC score	0.056159 (rank : 119)
Query Neighborhood Hits	106	Target Neighborhood Hits	519	Shared Neighborhood Hits	20
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PA24D_MOUSE
θ value	θ > 10 (rank : 145)	NC score	0.084404 (rank : 65)
Query Neighborhood Hits	106	Target Neighborhood Hits	100	Shared Neighborhood Hits	48
SwissProt Accessions	Q50L43, Q3TJC5	Gene names	Pla2g4d
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

PCLO_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.065018 (rank : 102)
Query Neighborhood Hits	106	Target Neighborhood Hits	2046	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PCLO_MOUSE
θ value	θ > 10 (rank : 147)	NC score	0.063397 (rank : 104)
Query Neighborhood Hits	106	Target Neighborhood Hits	2275	Shared Neighborhood Hits	68
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RASA1_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.066261 (rank : 100)
Query Neighborhood Hits	106	Target Neighborhood Hits	258	Shared Neighborhood Hits	22
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

RASA2_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.053320 (rank : 137)
Query Neighborhood Hits	106	Target Neighborhood Hits	157	Shared Neighborhood Hits	45
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

RASA2_MOUSE
θ value	θ > 10 (rank : 150)	NC score	0.055111 (rank : 127)
Query Neighborhood Hits	106	Target Neighborhood Hits	159	Shared Neighborhood Hits	48
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

RASA3_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.056036 (rank : 121)
Query Neighborhood Hits	106	Target Neighborhood Hits	166	Shared Neighborhood Hits	46
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

RASL1_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.098668 (rank : 50)
Query Neighborhood Hits	106	Target Neighborhood Hits	142	Shared Neighborhood Hits	56
SwissProt Accessions	O95294, Q52M03, Q96CC7	Gene names	RASAL1, RASAL
Domain Architecture
Description	RasGAP-activating-like protein 1.

RBBP8_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.054104 (rank : 133)
Query Neighborhood Hits	106	Target Neighborhood Hits	476	Shared Neighborhood Hits	17
SwissProt Accessions	Q99708, O75371	Gene names	RBBP8, CTIP
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 8 (RBBP-8) (CtBP-interacting protein) (CtIP) (Retinoblastoma-interacting protein and myosin-like) (RIM).

RFIP2_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.057864 (rank : 113)
Query Neighborhood Hits	106	Target Neighborhood Hits	97	Shared Neighborhood Hits	46
SwissProt Accessions	Q7L804, Q9Y2F0	Gene names	RAB11FIP2, KIAA0941
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 2 (Rab11-FIP2) (NRip11).

RIMS1_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.054758 (rank : 130)
Query Neighborhood Hits	106	Target Neighborhood Hits	437	Shared Neighborhood Hits	45
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

RIMS2_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.056476 (rank : 117)
Query Neighborhood Hits	106	Target Neighborhood Hits	342	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.055584 (rank : 123)
Query Neighborhood Hits	106	Target Neighborhood Hits	376	Shared Neighborhood Hits	50
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

SH22A_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.072892 (rank : 84)
Query Neighborhood Hits	106	Target Neighborhood Hits	144	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NP31, O43817, Q9UPA7	Gene names	SH2D2A, SCAP, TSAD, VRAP
Domain Architecture
Description	SH2 domain protein 2A (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein) (SH2 domain-containing adapter protein).

SH22A_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.064047 (rank : 103)
Query Neighborhood Hits	106	Target Neighborhood Hits	179	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

SH24A_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.071229 (rank : 89)
Query Neighborhood Hits	106	Target Neighborhood Hits	455	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H788, Q5XKC1, Q6NXE9, Q86YM2, Q96C88, Q9H7F7	Gene names	SH2D4A, SH2A
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A (Protein SH(2)A).

SH3K1_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.051510 (rank : 147)
Query Neighborhood Hits	106	Target Neighborhood Hits	341	Shared Neighborhood Hits	9
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

SH3K1_MOUSE
θ value	θ > 10 (rank : 162)	NC score	0.052093 (rank : 140)
Query Neighborhood Hits	106	Target Neighborhood Hits	332	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

SHE_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.051203 (rank : 150)
Query Neighborhood Hits	106	Target Neighborhood Hits	164	Shared Neighborhood Hits	5
SwissProt Accessions	Q5VZ18, Q8TEQ5	Gene names	SHE
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

SHE_MOUSE
θ value	θ > 10 (rank : 164)	NC score	0.051884 (rank : 144)
Query Neighborhood Hits	106	Target Neighborhood Hits	169	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BSD5, Q3TZT0	Gene names	She
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

SYT10_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.109163 (rank : 40)
Query Neighborhood Hits	106	Target Neighborhood Hits	133	Shared Neighborhood Hits	54
SwissProt Accessions	Q9R0N4	Gene names	Syt10
Domain Architecture
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

SYT12_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.089440 (rank : 60)
Query Neighborhood Hits	106	Target Neighborhood Hits	100	Shared Neighborhood Hits	39
SwissProt Accessions	Q8IV01	Gene names	SYT12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

SYT12_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.091990 (rank : 56)
Query Neighborhood Hits	106	Target Neighborhood Hits	102	Shared Neighborhood Hits	40
SwissProt Accessions	Q920N7	Gene names	Syt12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

SYT13_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.086209 (rank : 63)
Query Neighborhood Hits	106	Target Neighborhood Hits	76	Shared Neighborhood Hits	41
SwissProt Accessions	Q7L8C5, Q9BQS3, Q9H041, Q9P2C0	Gene names	SYT13, KIAA1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

SYT13_MOUSE
θ value	θ > 10 (rank : 169)	NC score	0.084385 (rank : 66)
Query Neighborhood Hits	106	Target Neighborhood Hits	69	Shared Neighborhood Hits	39
SwissProt Accessions	Q9EQT6, Q6ZPR2, Q8BRK6	Gene names	Syt13, Kiaa1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

SYT14_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.077886 (rank : 75)
Query Neighborhood Hits	106	Target Neighborhood Hits	81	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NB59, Q5THX7, Q707N3, Q707N4, Q707N5, Q707N6, Q707N7	Gene names	SYT14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

SYT14_MOUSE
θ value	θ > 10 (rank : 171)	NC score	0.080095 (rank : 73)
Query Neighborhood Hits	106	Target Neighborhood Hits	82	Shared Neighborhood Hits	34
SwissProt Accessions	Q7TN84	Gene names	Syt14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

SYT15_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.093014 (rank : 52)
Query Neighborhood Hits	106	Target Neighborhood Hits	112	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BQS2, Q7Z439, Q7Z440	Gene names	SYT15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV) (Chr10Syt).

SYT15_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.090072 (rank : 59)
Query Neighborhood Hits	106	Target Neighborhood Hits	100	Shared Neighborhood Hits	44
SwissProt Accessions	Q8C6N3, Q7TN81, Q7TN82, Q8C999	Gene names	Syt15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV).

SYT4_MOUSE
θ value	θ > 10 (rank : 174)	NC score	0.112152 (rank : 38)
Query Neighborhood Hits	106	Target Neighborhood Hits	123	Shared Neighborhood Hits	52
SwissProt Accessions	P40749, Q3UFC1, Q8BGH3, Q8BRL6	Gene names	Syt4, Syt3
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

SYT6_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.105333 (rank : 43)
Query Neighborhood Hits	106	Target Neighborhood Hits	138	Shared Neighborhood Hits	53
SwissProt Accessions	Q5T7P8	Gene names	SYT6
Domain Architecture	No domain graphic available
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

SYT6_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.105746 (rank : 42)
Query Neighborhood Hits	106	Target Neighborhood Hits	132	Shared Neighborhood Hits	53
SwissProt Accessions	Q9R0N8	Gene names	Syt6
Domain Architecture
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

SYT8_MOUSE
θ value	θ > 10 (rank : 177)	NC score	0.095571 (rank : 51)
Query Neighborhood Hits	106	Target Neighborhood Hits	94	Shared Neighborhood Hits	40
SwissProt Accessions	Q9R0N6, Q64366, Q8C6E7	Gene names	Syt8
Domain Architecture
Description	Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII).

SYTL1_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.080722 (rank : 71)
Query Neighborhood Hits	106	Target Neighborhood Hits	227	Shared Neighborhood Hits	46
SwissProt Accessions	Q8IYJ3, Q96BB6, Q96GU6, Q96S89, Q96SI0	Gene names	SYTL1, SLP1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1) (SB146).

SYTL1_MOUSE
θ value	θ > 10 (rank : 179)	NC score	0.074463 (rank : 81)
Query Neighborhood Hits	106	Target Neighborhood Hits	314	Shared Neighborhood Hits	43
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

SYTL2_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.076665 (rank : 77)
Query Neighborhood Hits	106	Target Neighborhood Hits	248	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

SYTL2_MOUSE
θ value	θ > 10 (rank : 181)	NC score	0.075581 (rank : 79)
Query Neighborhood Hits	106	Target Neighborhood Hits	253	Shared Neighborhood Hits	49
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

SYTL3_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.069698 (rank : 94)
Query Neighborhood Hits	106	Target Neighborhood Hits	110	Shared Neighborhood Hits	39
SwissProt Accessions	Q99N48, Q8C506, Q99N47, Q99N49, Q99N54, Q99N79	Gene names	Sytl3, Slp3
Domain Architecture
Description	Synaptotagmin-like protein 3 (Exophilin-6).

SYTL4_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.082824 (rank : 68)
Query Neighborhood Hits	106	Target Neighborhood Hits	138	Shared Neighborhood Hits	47
SwissProt Accessions	Q96C24, Q5H9J3, Q5JPG8, Q8N9P4, Q9H4R0, Q9H4R1	Gene names	SYTL4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

SYTL4_MOUSE
θ value	θ > 10 (rank : 184)	NC score	0.082653 (rank : 69)
Query Neighborhood Hits	106	Target Neighborhood Hits	137	Shared Neighborhood Hits	49
SwissProt Accessions	Q9R0Q1, Q8R321, Q9R0Q0	Gene names	Sytl4, Slp4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

SYTL5_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.080398 (rank : 72)
Query Neighborhood Hits	106	Target Neighborhood Hits	237	Shared Neighborhood Hits	52
SwissProt Accessions	Q8TDW5	Gene names	SYTL5, SLP5
Domain Architecture
Description	Synaptotagmin-like protein 5.

SYTL5_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.078513 (rank : 74)
Query Neighborhood Hits	106	Target Neighborhood Hits	154	Shared Neighborhood Hits	52
SwissProt Accessions	Q80T23, Q812E5	Gene names	Sytl5, Slp5
Domain Architecture
Description	Synaptotagmin-like protein 5.

UN13A_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.056757 (rank : 115)
Query Neighborhood Hits	106	Target Neighborhood Hits	285	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

UN13B_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.055679 (rank : 122)
Query Neighborhood Hits	106	Target Neighborhood Hits	217	Shared Neighborhood Hits	54
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

UN13B_MOUSE
θ value	θ > 10 (rank : 189)	NC score	0.062812 (rank : 107)
Query Neighborhood Hits	106	Target Neighborhood Hits	210	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

UN13D_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.092100 (rank : 55)
Query Neighborhood Hits	106	Target Neighborhood Hits	117	Shared Neighborhood Hits	50
SwissProt Accessions	Q70J99, Q9H7K5	Gene names	UNC13D
Domain Architecture	No domain graphic available
Description	Unc-13 homolog D (Munc13-4).

VAV2_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.051954 (rank : 142)
Query Neighborhood Hits	106	Target Neighborhood Hits	453	Shared Neighborhood Hits	14
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

VAV3_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.057964 (rank : 112)
Query Neighborhood Hits	106	Target Neighborhood Hits	398	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

VAV3_MOUSE
θ value	θ > 10 (rank : 193)	NC score	0.055469 (rank : 124)
Query Neighborhood Hits	106	Target Neighborhood Hits	404	Shared Neighborhood Hits	14
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

VAV_MOUSE
θ value	θ > 10 (rank : 194)	NC score	0.050427 (rank : 154)
Query Neighborhood Hits	106	Target Neighborhood Hits	430	Shared Neighborhood Hits	14
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

Hits sorted by NC score

PLCD1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	106	Target Neighborhood Hits	106	Shared Neighborhood Hits	106
SwissProt Accessions	Q8R3B1	Gene names	Plcd1, Plcd
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

PLCD1_HUMAN
NC score	0.989088 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	106	Target Neighborhood Hits	93	Shared Neighborhood Hits	73
SwissProt Accessions	P51178	Gene names	PLCD1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

PLCB3_MOUSE
NC score	0.794116 (rank : 3)	θ value	2.58187e-47 (rank : 11)
Query Neighborhood Hits	106	Target Neighborhood Hits	344	Shared Neighborhood Hits	17
SwissProt Accessions	P51432	Gene names	Plcb3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

PLCB2_HUMAN
NC score	0.775201 (rank : 4)	θ value	2.47191e-82 (rank : 4)
Query Neighborhood Hits	106	Target Neighborhood Hits	608	Shared Neighborhood Hits	26
SwissProt Accessions	Q00722	Gene names	PLCB2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-2) (PLC-beta-2).

PLCB1_MOUSE
NC score	0.770181 (rank : 5)	θ value	1.2268e-81 (rank : 6)
Query Neighborhood Hits	106	Target Neighborhood Hits	531	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z1B3, Q62075, Q8K5A5, Q8K5A6, Q9Z0E5, Q9Z2T5	Gene names	Plcb1, Plcb
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

PLCB3_HUMAN
NC score	0.766409 (rank : 6)	θ value	8.87376e-48 (rank : 10)
Query Neighborhood Hits	106	Target Neighborhood Hits	445	Shared Neighborhood Hits	22
SwissProt Accessions	Q01970	Gene names	PLCB3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

PLCB1_HUMAN
NC score	0.759512 (rank : 7)	θ value	3.22841e-82 (rank : 5)
Query Neighborhood Hits	106	Target Neighborhood Hits	614	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NQ66, O60325, Q5TFF7, Q5TGC9, Q8IV93, Q9BQW2, Q9H4H2, Q9H8H5, Q9NQ65, Q9NQH9, Q9NTH4, Q9UJP6, Q9UM26	Gene names	PLCB1, KIAA0581
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

PLCB4_HUMAN
NC score	0.681046 (rank : 8)	θ value	7.93343e-89 (rank : 3)
Query Neighborhood Hits	106	Target Neighborhood Hits	658	Shared Neighborhood Hits	27
SwissProt Accessions	Q15147, Q5JYS8, Q5JYT0, Q5JYT4, Q9BQW5, Q9BQW6, Q9BQW8, Q9UJQ2	Gene names	PLCB4
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-4) (PLC-beta-4).

PLCG2_HUMAN
NC score	0.632263 (rank : 9)	θ value	2.32439e-64 (rank : 7)
Query Neighborhood Hits	106	Target Neighborhood Hits	280	Shared Neighborhood Hits	25
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

PLCG1_HUMAN
NC score	0.623952 (rank : 10)	θ value	1.66964e-54 (rank : 9)
Query Neighborhood Hits	106	Target Neighborhood Hits	293	Shared Neighborhood Hits	28
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLCG1_MOUSE
NC score	0.618546 (rank : 11)	θ value	9.78833e-55 (rank : 8)
Query Neighborhood Hits	106	Target Neighborhood Hits	314	Shared Neighborhood Hits	28
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

DOC2A_MOUSE
NC score	0.154175 (rank : 12)	θ value	0.47712 (rank : 42)
Query Neighborhood Hits	106	Target Neighborhood Hits	140	Shared Neighborhood Hits	60
SwissProt Accessions	Q7TNF0	Gene names	Doc2a
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha).

DOC2A_HUMAN
NC score	0.149092 (rank : 13)	θ value	1.06291 (rank : 51)
Query Neighborhood Hits	106	Target Neighborhood Hits	144	Shared Neighborhood Hits	59
SwissProt Accessions	Q14183, Q6P4G4, Q7Z5G0, Q8IVX0	Gene names	DOC2A
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha) (Doc2).

SYT1_HUMAN
NC score	0.145419 (rank : 14)	θ value	0.00020696 (rank : 12)
Query Neighborhood Hits	106	Target Neighborhood Hits	150	Shared Neighborhood Hits	55
SwissProt Accessions	P21579	Gene names	SYT1, SYT
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT1_MOUSE
NC score	0.145410 (rank : 15)	θ value	0.00020696 (rank : 13)
Query Neighborhood Hits	106	Target Neighborhood Hits	150	Shared Neighborhood Hits	55
SwissProt Accessions	P46096	Gene names	Syt1
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

DOC2B_MOUSE
NC score	0.144179 (rank : 16)	θ value	0.365318 (rank : 40)
Query Neighborhood Hits	106	Target Neighborhood Hits	169	Shared Neighborhood Hits	58
SwissProt Accessions	P70169, Q6NXK3	Gene names	Doc2b
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

DOC2B_HUMAN
NC score	0.143814 (rank : 17)	θ value	0.62314 (rank : 47)
Query Neighborhood Hits	106	Target Neighborhood Hits	150	Shared Neighborhood Hits	58
SwissProt Accessions	Q14184	Gene names	DOC2B
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

SYT5_HUMAN
NC score	0.138082 (rank : 18)	θ value	0.0113563 (rank : 21)
Query Neighborhood Hits	106	Target Neighborhood Hits	138	Shared Neighborhood Hits	55
SwissProt Accessions	O00445, Q86X72	Gene names	SYT5
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV).

SYT5_MOUSE
NC score	0.137292 (rank : 19)	θ value	0.0252991 (rank : 23)
Query Neighborhood Hits	106	Target Neighborhood Hits	140	Shared Neighborhood Hits	56
SwissProt Accessions	Q9R0N5	Gene names	Syt5, Syt9
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV) (Synaptotagmin IX).

SYT7_MOUSE
NC score	0.137150 (rank : 20)	θ value	0.125558 (rank : 30)
Query Neighborhood Hits	106	Target Neighborhood Hits	137	Shared Neighborhood Hits	55
SwissProt Accessions	Q9R0N7	Gene names	Syt7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

SYT7_HUMAN
NC score	0.136542 (rank : 21)	θ value	0.21417 (rank : 37)
Query Neighborhood Hits	106	Target Neighborhood Hits	137	Shared Neighborhood Hits	53
SwissProt Accessions	O43581	Gene names	SYT7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

SYT2_MOUSE
NC score	0.133761 (rank : 22)	θ value	0.0330416 (rank : 25)
Query Neighborhood Hits	106	Target Neighborhood Hits	143	Shared Neighborhood Hits	55
SwissProt Accessions	P46097, Q8R0E1	Gene names	Syt2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT2_HUMAN
NC score	0.133002 (rank : 23)	θ value	0.0330416 (rank : 24)
Query Neighborhood Hits	106	Target Neighborhood Hits	142	Shared Neighborhood Hits	55
SwissProt Accessions	Q8N9I0, Q496K5, Q8NBE5	Gene names	SYT2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

K0528_HUMAN
NC score	0.130691 (rank : 24)	θ value	0.21417 (rank : 34)
Query Neighborhood Hits	106	Target Neighborhood Hits	96	Shared Neighborhood Hits	47
SwissProt Accessions	Q86YS7, O60280, Q7Z619, Q86SU3	Gene names	KIAA0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

K0528_MOUSE
NC score	0.130481 (rank : 25)	θ value	0.21417 (rank : 35)
Query Neighborhood Hits	106	Target Neighborhood Hits	102	Shared Neighborhood Hits	47
SwissProt Accessions	Q7TPS5, Q3TQY6, Q6A052, Q80VA1, Q8C0U3, Q8CID5, Q9CS85	Gene names	Kiaa0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

SYT11_HUMAN
NC score	0.124460 (rank : 26)	θ value	1.06291 (rank : 54)
Query Neighborhood Hits	106	Target Neighborhood Hits	113	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BT88, Q14998, Q68CT5, Q8IXU3, Q96SU2	Gene names	SYT11, KIAA0080
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

SYT11_MOUSE
NC score	0.124329 (rank : 27)	θ value	1.06291 (rank : 55)
Query Neighborhood Hits	106	Target Neighborhood Hits	116	Shared Neighborhood Hits	48
SwissProt Accessions	Q9R0N3	Gene names	Syt11
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

SYT3_HUMAN
NC score	0.123866 (rank : 28)	θ value	0.47712 (rank : 46)
Query Neighborhood Hits	106	Target Neighborhood Hits	145	Shared Neighborhood Hits	55
SwissProt Accessions	Q9BQG1, Q8N5Z1, Q8N640	Gene names	SYT3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

RASL2_HUMAN
NC score	0.123710 (rank : 29)	θ value	0.00665767 (rank : 17)
Query Neighborhood Hits	106	Target Neighborhood Hits	161	Shared Neighborhood Hits	55
SwissProt Accessions	O43374, O60286, Q86UW3, Q96QU0	Gene names	RASA4, CAPRI, GAPL, KIAA0538
Domain Architecture
Description	Ras GTPase-activating protein 4 (RasGAP-activating-like protein 2) (Calcium-promoted Ras inactivator).

SYT3_MOUSE
NC score	0.123452 (rank : 30)	θ value	0.62314 (rank : 49)
Query Neighborhood Hits	106	Target Neighborhood Hits	147	Shared Neighborhood Hits	55
SwissProt Accessions	O35681, P97791, Q80WV1	Gene names	Syt3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

RP3A_MOUSE
NC score	0.118392 (rank : 31)	θ value	3.0926 (rank : 74)
Query Neighborhood Hits	106	Target Neighborhood Hits	510	Shared Neighborhood Hits	54
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

RP3A_HUMAN
NC score	0.118224 (rank : 32)	θ value	3.0926 (rank : 73)
Query Neighborhood Hits	106	Target Neighborhood Hits	305	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SYT4_HUMAN
NC score	0.114014 (rank : 33)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	106	Target Neighborhood Hits	121	Shared Neighborhood Hits	51
SwissProt Accessions	Q9H2B2, Q9P2K4	Gene names	SYT4, KIAA1342
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

SYT9_HUMAN
NC score	0.113309 (rank : 34)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	106	Target Neighborhood Hits	144	Shared Neighborhood Hits	56
SwissProt Accessions	Q86SS6	Gene names	SYT9
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX).

DOC2G_MOUSE
NC score	0.112923 (rank : 35)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	106	Target Neighborhood Hits	125	Shared Neighborhood Hits	49
SwissProt Accessions	Q9ESN1, Q6P8R8	Gene names	Doc2g
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein gamma (Doc2-gamma).

MYOF_HUMAN
NC score	0.112581 (rank : 36)	θ value	0.0563607 (rank : 26)
Query Neighborhood Hits	106	Target Neighborhood Hits	147	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NZM1, Q9HBU3, Q9NZM0, Q9ULL3, Q9Y4U4	Gene names	FER1L3, KIAA1207, MYOF
Domain Architecture
Description	Myoferlin (Fer-1-like protein 3).

SYT9_MOUSE
NC score	0.112342 (rank : 37)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	106	Target Neighborhood Hits	148	Shared Neighborhood Hits	56
SwissProt Accessions	Q9R0N9, Q8C280	Gene names	Syt9, Syt5
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX) (Synaptotagmin V).

SYT4_MOUSE
NC score	0.112152 (rank : 38)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	106	Target Neighborhood Hits	123	Shared Neighborhood Hits	52
SwissProt Accessions	P40749, Q3UFC1, Q8BGH3, Q8BRL6	Gene names	Syt4, Syt3
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

SYT10_HUMAN
NC score	0.109270 (rank : 39)	θ value	3.0926 (rank : 76)
Query Neighborhood Hits	106	Target Neighborhood Hits	134	Shared Neighborhood Hits	54
SwissProt Accessions	Q6XYQ8	Gene names	SYT10
Domain Architecture	No domain graphic available
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

SYT10_MOUSE
NC score	0.109163 (rank : 40)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	106	Target Neighborhood Hits	133	Shared Neighborhood Hits	54
SwissProt Accessions	Q9R0N4	Gene names	Syt10
Domain Architecture
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

CPNE6_MOUSE
NC score	0.105769 (rank : 41)	θ value	0.000786445 (rank : 15)
Query Neighborhood Hits	106	Target Neighborhood Hits	87	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z140	Gene names	Cpne6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

SYT6_MOUSE
NC score	0.105746 (rank : 42)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	106	Target Neighborhood Hits	132	Shared Neighborhood Hits	53
SwissProt Accessions	Q9R0N8	Gene names	Syt6
Domain Architecture
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

SYT6_HUMAN
NC score	0.105333 (rank : 43)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	106	Target Neighborhood Hits	138	Shared Neighborhood Hits	53
SwissProt Accessions	Q5T7P8	Gene names	SYT6
Domain Architecture	No domain graphic available
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

DYSF_MOUSE
NC score	0.102963 (rank : 44)	θ value	0.0961366 (rank : 28)
Query Neighborhood Hits	106	Target Neighborhood Hits	162	Shared Neighborhood Hits	53
SwissProt Accessions	Q9ESD7, Q9QXC0	Gene names	Dysf, Fer1l1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

CPNE6_HUMAN
NC score	0.102919 (rank : 45)	θ value	0.000461057 (rank : 14)
Query Neighborhood Hits	106	Target Neighborhood Hits	85	Shared Neighborhood Hits	46
SwissProt Accessions	O95741, Q53HA6, Q8WVG1	Gene names	CPNE6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

BAIP3_HUMAN
NC score	0.102759 (rank : 46)	θ value	1.38821 (rank : 57)
Query Neighborhood Hits	106	Target Neighborhood Hits	108	Shared Neighborhood Hits	47
SwissProt Accessions	O94812, O94839, Q2M226, Q658J2, Q76N05, Q96RZ3, Q9UJK1	Gene names	BAIAP3, KIAA0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

NED4L_HUMAN
NC score	0.101702 (rank : 47)	θ value	0.00869519 (rank : 18)
Query Neighborhood Hits	106	Target Neighborhood Hits	238	Shared Neighborhood Hits	57
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NED4L_MOUSE
NC score	0.100915 (rank : 48)	θ value	0.00869519 (rank : 19)
Query Neighborhood Hits	106	Target Neighborhood Hits	231	Shared Neighborhood Hits	57
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

BAIP3_MOUSE
NC score	0.099000 (rank : 49)	θ value	3.0926 (rank : 68)
Query Neighborhood Hits	106	Target Neighborhood Hits	112	Shared Neighborhood Hits	50
SwissProt Accessions	Q80TT2, Q6RUT4	Gene names	Baiap3, Gm937, Kiaa0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

RASL1_HUMAN
NC score	0.098668 (rank : 50)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	106	Target Neighborhood Hits	142	Shared Neighborhood Hits	56
SwissProt Accessions	O95294, Q52M03, Q96CC7	Gene names	RASAL1, RASAL
Domain Architecture
Description	RasGAP-activating-like protein 1.

SYT8_MOUSE
NC score	0.095571 (rank : 51)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	106	Target Neighborhood Hits	94	Shared Neighborhood Hits	40
SwissProt Accessions	Q9R0N6, Q64366, Q8C6E7	Gene names	Syt8
Domain Architecture
Description	Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII).

SYT15_HUMAN
NC score	0.093014 (rank : 52)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	106	Target Neighborhood Hits	112	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BQS2, Q7Z439, Q7Z440	Gene names	SYT15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV) (Chr10Syt).

RASL1_MOUSE
NC score	0.092563 (rank : 53)	θ value	4.03905 (rank : 80)
Query Neighborhood Hits	106	Target Neighborhood Hits	148	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Z268	Gene names	Rasal1, Rasal
Domain Architecture
Description	RasGAP-activating-like protein 1.

AB2BP_MOUSE
NC score	0.092303 (rank : 54)	θ value	0.163984 (rank : 31)
Query Neighborhood Hits	106	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D6J4, Q3TYZ9, Q9ESR0	Gene names	Apba2bp, Xb51
Domain Architecture
Description	Amyloid beta A4 protein-binding family A member 2-binding protein (X11L-binding protein 51) (mXB51).

UN13D_HUMAN
NC score	0.092100 (rank : 55)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	106	Target Neighborhood Hits	117	Shared Neighborhood Hits	50
SwissProt Accessions	Q70J99, Q9H7K5	Gene names	UNC13D
Domain Architecture	No domain graphic available
Description	Unc-13 homolog D (Munc13-4).

SYT12_MOUSE
NC score	0.091990 (rank : 56)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	106	Target Neighborhood Hits	102	Shared Neighborhood Hits	40
SwissProt Accessions	Q920N7	Gene names	Syt12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

FA62A_HUMAN
NC score	0.091783 (rank : 57)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	106	Target Neighborhood Hits	168	Shared Neighborhood Hits	55
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

FA62A_MOUSE
NC score	0.091366 (rank : 58)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	106	Target Neighborhood Hits	155	Shared Neighborhood Hits	54
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

SYT15_MOUSE
NC score	0.090072 (rank : 59)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	106	Target Neighborhood Hits	100	Shared Neighborhood Hits	44
SwissProt Accessions	Q8C6N3, Q7TN81, Q7TN82, Q8C999	Gene names	Syt15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV).

SYT12_HUMAN
NC score	0.089440 (rank : 60)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	106	Target Neighborhood Hits	100	Shared Neighborhood Hits	39
SwissProt Accessions	Q8IV01	Gene names	SYT12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

NEDD4_MOUSE
NC score	0.087969 (rank : 61)	θ value	0.0563607 (rank : 27)
Query Neighborhood Hits	106	Target Neighborhood Hits	212	Shared Neighborhood Hits	53
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

NEDD4_HUMAN
NC score	0.086366 (rank : 62)	θ value	0.163984 (rank : 32)
Query Neighborhood Hits	106	Target Neighborhood Hits	214	Shared Neighborhood Hits	53
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

SYT13_HUMAN
NC score	0.086209 (rank : 63)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	106	Target Neighborhood Hits	76	Shared Neighborhood Hits	41
SwissProt Accessions	Q7L8C5, Q9BQS3, Q9H041, Q9P2C0	Gene names	SYT13, KIAA1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

AB2BP_HUMAN
NC score	0.085259 (rank : 64)	θ value	0.47712 (rank : 41)
Query Neighborhood Hits	106	Target Neighborhood Hits	35	Shared Neighborhood Hits	6
SwissProt Accessions	Q96P71, Q5JWF6, Q5JWF7, Q86VV1, Q9H433, Q9H8G8, Q9HBW7, Q9HCQ9	Gene names	APBA2BP, NECAB3, NIP1, XB51
Domain Architecture
Description	Amyloid beta A4 protein-binding family A member 2-binding protein (Neuronal calcium-binding protein 3) (NECAB 3) (X11L-binding protein 51) (Nek2-interacting protein 1).

PA24D_MOUSE
NC score	0.084404 (rank : 65)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	106	Target Neighborhood Hits	100	Shared Neighborhood Hits	48
SwissProt Accessions	Q50L43, Q3TJC5	Gene names	Pla2g4d
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

SYT13_MOUSE
NC score	0.084385 (rank : 66)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	106	Target Neighborhood Hits	69	Shared Neighborhood Hits	39
SwissProt Accessions	Q9EQT6, Q6ZPR2, Q8BRK6	Gene names	Syt13, Kiaa1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

DYSF_HUMAN
NC score	0.084278 (rank : 67)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	106	Target Neighborhood Hits	170	Shared Neighborhood Hits	56
SwissProt Accessions	O75923, O75696, Q9UEN7	Gene names	DYSF, FER1L1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

SYTL4_HUMAN
NC score	0.082824 (rank : 68)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	106	Target Neighborhood Hits	138	Shared Neighborhood Hits	47
SwissProt Accessions	Q96C24, Q5H9J3, Q5JPG8, Q8N9P4, Q9H4R0, Q9H4R1	Gene names	SYTL4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

SYTL4_MOUSE
NC score	0.082653 (rank : 69)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	106	Target Neighborhood Hits	137	Shared Neighborhood Hits	49
SwissProt Accessions	Q9R0Q1, Q8R321, Q9R0Q0	Gene names	Sytl4, Slp4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

CPNE7_HUMAN
NC score	0.082273 (rank : 70)	θ value	0.365318 (rank : 39)
Query Neighborhood Hits	106	Target Neighborhood Hits	92	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UBL6	Gene names	CPNE7
Domain Architecture
Description	Copine-7 (Copine VII).

SYTL1_HUMAN
NC score	0.080722 (rank : 71)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	106	Target Neighborhood Hits	227	Shared Neighborhood Hits	46
SwissProt Accessions	Q8IYJ3, Q96BB6, Q96GU6, Q96S89, Q96SI0	Gene names	SYTL1, SLP1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1) (SB146).

SYTL5_HUMAN
NC score	0.080398 (rank : 72)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	106	Target Neighborhood Hits	237	Shared Neighborhood Hits	52
SwissProt Accessions	Q8TDW5	Gene names	SYTL5, SLP5
Domain Architecture
Description	Synaptotagmin-like protein 5.

SYT14_MOUSE
NC score	0.080095 (rank : 73)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	106	Target Neighborhood Hits	82	Shared Neighborhood Hits	34
SwissProt Accessions	Q7TN84	Gene names	Syt14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

SYTL5_MOUSE
NC score	0.078513 (rank : 74)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	106	Target Neighborhood Hits	154	Shared Neighborhood Hits	52
SwissProt Accessions	Q80T23, Q812E5	Gene names	Sytl5, Slp5
Domain Architecture
Description	Synaptotagmin-like protein 5.

SYT14_HUMAN
NC score	0.077886 (rank : 75)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	106	Target Neighborhood Hits	81	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NB59, Q5THX7, Q707N3, Q707N4, Q707N5, Q707N6, Q707N7	Gene names	SYT14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

ITSN2_MOUSE
NC score	0.076893 (rank : 76)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	106	Target Neighborhood Hits	1371	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

SYTL2_HUMAN
NC score	0.076665 (rank : 77)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	106	Target Neighborhood Hits	248	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

ITSN1_HUMAN
NC score	0.076165 (rank : 78)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	106	Target Neighborhood Hits	1757	Shared Neighborhood Hits	78
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

SYTL2_MOUSE
NC score	0.075581 (rank : 79)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	106	Target Neighborhood Hits	253	Shared Neighborhood Hits	49
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

LCP2_MOUSE
NC score	0.074913 (rank : 80)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	106	Target Neighborhood Hits	177	Shared Neighborhood Hits	5
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

SYTL1_MOUSE
NC score	0.074463 (rank : 81)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	106	Target Neighborhood Hits	314	Shared Neighborhood Hits	43
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

CPNE2_HUMAN
NC score	0.073911 (rank : 82)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	106	Target Neighborhood Hits	75	Shared Neighborhood Hits	46
SwissProt Accessions	Q96FN4, Q68D19, Q86XP9	Gene names	CPNE2
Domain Architecture
Description	Copine-2 (Copine II).

CPNE3_MOUSE
NC score	0.073748 (rank : 83)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	106	Target Neighborhood Hits	90	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BT60, Q5CZX9, Q5DU22	Gene names	Cpne3, Kiaa0636
Domain Architecture
Description	Copine-3 (Copine III).

SH22A_HUMAN
NC score	0.072892 (rank : 84)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	106	Target Neighborhood Hits	144	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NP31, O43817, Q9UPA7	Gene names	SH2D2A, SCAP, TSAD, VRAP
Domain Architecture
Description	SH2 domain protein 2A (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein) (SH2 domain-containing adapter protein).

CPNE3_HUMAN
NC score	0.072708 (rank : 85)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	106	Target Neighborhood Hits	90	Shared Neighborhood Hits	45
SwissProt Accessions	O75131, Q8IYA1	Gene names	CPNE3, CPN3, KIAA0636
Domain Architecture
Description	Copine-3 (Copine III).

CPNE2_MOUSE
NC score	0.072700 (rank : 86)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	106	Target Neighborhood Hits	82	Shared Neighborhood Hits	46
SwissProt Accessions	P59108, Q8K1D7	Gene names	Cpne2
Domain Architecture
Description	Copine-2 (Copine II).

ITSN1_MOUSE
NC score	0.072138 (rank : 87)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	106	Target Neighborhood Hits	1669	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

ITSN2_HUMAN
NC score	0.071604 (rank : 88)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	106	Target Neighborhood Hits	1173	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

SH24A_HUMAN
NC score	0.071229 (rank : 89)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	106	Target Neighborhood Hits	455	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H788, Q5XKC1, Q6NXE9, Q86YM2, Q96C88, Q9H7F7	Gene names	SH2D4A, SH2A
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A (Protein SH(2)A).

CPNE5_MOUSE
NC score	0.070722 (rank : 90)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	106	Target Neighborhood Hits	86	Shared Neighborhood Hits	48
SwissProt Accessions	Q8JZW4	Gene names	Cpne5
Domain Architecture
Description	Copine-5 (Copine V).

CPNE5_HUMAN
NC score	0.070579 (rank : 91)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	106	Target Neighborhood Hits	88	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HCH3	Gene names	CPNE5, KIAA1599
Domain Architecture
Description	Copine-5 (Copine V).

CPNE8_HUMAN
NC score	0.070302 (rank : 92)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	106	Target Neighborhood Hits	86	Shared Neighborhood Hits	46
SwissProt Accessions	Q86YQ8, Q2TB41	Gene names	CPNE8
Domain Architecture
Description	Copine-8 (Copine VIII).

OTOF_HUMAN
NC score	0.069899 (rank : 93)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	106	Target Neighborhood Hits	168	Shared Neighborhood Hits	53
SwissProt Accessions	Q9HC10, Q9HC08, Q9HC09, Q9Y650	Gene names	OTOF, FER1L2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

SYTL3_MOUSE
NC score	0.069698 (rank : 94)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	106	Target Neighborhood Hits	110	Shared Neighborhood Hits	39
SwissProt Accessions	Q99N48, Q8C506, Q99N47, Q99N49, Q99N54, Q99N79	Gene names	Sytl3, Slp3
Domain Architecture
Description	Synaptotagmin-like protein 3 (Exophilin-6).

OTOF_MOUSE
NC score	0.069049 (rank : 95)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	106	Target Neighborhood Hits	196	Shared Neighborhood Hits	53
SwissProt Accessions	Q9ESF1, Q9ESF2	Gene names	Otof, Fer1l2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

CALU_MOUSE
NC score	0.069036 (rank : 96)	θ value	0.00665767 (rank : 16)
Query Neighborhood Hits	106	Target Neighborhood Hits	113	Shared Neighborhood Hits	8
SwissProt Accessions	O35887	Gene names	Calu
Domain Architecture
Description	Calumenin precursor (Crocalbin).

CPNE8_MOUSE
NC score	0.067571 (rank : 97)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	106	Target Neighborhood Hits	85	Shared Neighborhood Hits	45
SwissProt Accessions	Q9DC53, Q9CUZ8	Gene names	Cpne8
Domain Architecture
Description	Copine-8 (Copine VIII).

CPNE1_MOUSE
NC score	0.066845 (rank : 98)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	106	Target Neighborhood Hits	83	Shared Neighborhood Hits	45
SwissProt Accessions	Q8C166, Q925K4, Q925K5	Gene names	Cpne1
Domain Architecture
Description	Copine-1 (Copine I).

DAPP1_MOUSE
NC score	0.066283 (rank : 99)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	106	Target Neighborhood Hits	225	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

RASA1_HUMAN
NC score	0.066261 (rank : 100)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	106	Target Neighborhood Hits	258	Shared Neighborhood Hits	22
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

CALU_HUMAN
NC score	0.065862 (rank : 101)	θ value	0.0113563 (rank : 20)
Query Neighborhood Hits	106	Target Neighborhood Hits	114	Shared Neighborhood Hits	7
SwissProt Accessions	O43852, O60456, Q6FHB9, Q96RL3, Q9NR43	Gene names	CALU
Domain Architecture
Description	Calumenin precursor (Crocalbin) (IEF SSP 9302).

PCLO_HUMAN
NC score	0.065018 (rank : 102)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	106	Target Neighborhood Hits	2046	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SH22A_MOUSE
NC score	0.064047 (rank : 103)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	106	Target Neighborhood Hits	179	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

PCLO_MOUSE
NC score	0.063397 (rank : 104)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	106	Target Neighborhood Hits	2275	Shared Neighborhood Hits	68
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SEGN_MOUSE
NC score	0.063188 (rank : 105)	θ value	0.62314 (rank : 48)
Query Neighborhood Hits	106	Target Neighborhood Hits	101	Shared Neighborhood Hits	8
SwissProt Accessions	Q91WD9	Gene names	Scgn
Domain Architecture
Description	Secretagogin.

CPNE4_HUMAN
NC score	0.062937 (rank : 106)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	106	Target Neighborhood Hits	70	Shared Neighborhood Hits	38
SwissProt Accessions	Q96A23, Q8TEX1	Gene names	CPNE4
Domain Architecture
Description	Copine-4 (Copine IV) (Copine-8).

UN13B_MOUSE
NC score	0.062812 (rank : 107)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	106	Target Neighborhood Hits	210	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

CPNE4_MOUSE
NC score	0.062761 (rank : 108)	θ value	3.0926 (rank : 70)
Query Neighborhood Hits	106	Target Neighborhood Hits	67	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BLR2	Gene names	Cpne4
Domain Architecture	No domain graphic available
Description	Copine-4 (Copine IV).

CPNE1_HUMAN
NC score	0.061752 (rank : 109)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	106	Target Neighborhood Hits	70	Shared Neighborhood Hits	43
SwissProt Accessions	Q99829, Q6IBL3, Q9H243, Q9NTZ7	Gene names	CPNE1, CPN1
Domain Architecture
Description	Copine-1 (Copine I).

DAPP1_HUMAN
NC score	0.061088 (rank : 110)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	106	Target Neighborhood Hits	227	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

P55G_HUMAN
NC score	0.058496 (rank : 111)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	106	Target Neighborhood Hits	451	Shared Neighborhood Hits	18
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

VAV3_HUMAN
NC score	0.057964 (rank : 112)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	106	Target Neighborhood Hits	398	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

RFIP2_HUMAN
NC score	0.057864 (rank : 113)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	106	Target Neighborhood Hits	97	Shared Neighborhood Hits	46
SwissProt Accessions	Q7L804, Q9Y2F0	Gene names	RAB11FIP2, KIAA0941
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 2 (Rab11-FIP2) (NRip11).

LCP2_HUMAN
NC score	0.056965 (rank : 114)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	106	Target Neighborhood Hits	531	Shared Neighborhood Hits	6
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

UN13A_HUMAN
NC score	0.056757 (rank : 115)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	106	Target Neighborhood Hits	285	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

GRAP_MOUSE
NC score	0.056548 (rank : 116)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	106	Target Neighborhood Hits	309	Shared Neighborhood Hits	7
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

RIMS2_HUMAN
NC score	0.056476 (rank : 117)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	106	Target Neighborhood Hits	342	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

GRB2_MOUSE
NC score	0.056276 (rank : 118)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	106	Target Neighborhood Hits	312	Shared Neighborhood Hits	7
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

P85B_MOUSE
NC score	0.056159 (rank : 119)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	106	Target Neighborhood Hits	519	Shared Neighborhood Hits	20
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

CAF1A_HUMAN
NC score	0.056047 (rank : 120)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	106	Target Neighborhood Hits	750	Shared Neighborhood Hits	18
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

RASA3_HUMAN
NC score	0.056036 (rank : 121)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	106	Target Neighborhood Hits	166	Shared Neighborhood Hits	46
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

UN13B_HUMAN
NC score	0.055679 (rank : 122)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	106	Target Neighborhood Hits	217	Shared Neighborhood Hits	54
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

RIMS2_MOUSE
NC score	0.055584 (rank : 123)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	106	Target Neighborhood Hits	376	Shared Neighborhood Hits	50
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

VAV3_MOUSE
NC score	0.055469 (rank : 124)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	106	Target Neighborhood Hits	404	Shared Neighborhood Hits	14
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

CRK_HUMAN
NC score	0.055406 (rank : 125)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	106	Target Neighborhood Hits	308	Shared Neighborhood Hits	7
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

GRB2_HUMAN
NC score	0.055216 (rank : 126)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	106	Target Neighborhood Hits	310	Shared Neighborhood Hits	7
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

RASA2_MOUSE
NC score	0.055111 (rank : 127)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	106	Target Neighborhood Hits	159	Shared Neighborhood Hits	48
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

GRAP_HUMAN
NC score	0.054986 (rank : 128)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	106	Target Neighborhood Hits	307	Shared Neighborhood Hits	7
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

P55G_MOUSE
NC score	0.054828 (rank : 129)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	106	Target Neighborhood Hits	401	Shared Neighborhood Hits	16
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

RIMS1_HUMAN
NC score	0.054758 (rank : 130)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	106	Target Neighborhood Hits	437	Shared Neighborhood Hits	45
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

CRK_MOUSE
NC score	0.054270 (rank : 131)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	106	Target Neighborhood Hits	314	Shared Neighborhood Hits	7
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CCD19_HUMAN
NC score	0.054122 (rank : 132)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	106	Target Neighborhood Hits	639	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

RBBP8_HUMAN
NC score	0.054104 (rank : 133)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	106	Target Neighborhood Hits	476	Shared Neighborhood Hits	17
SwissProt Accessions	Q99708, O75371	Gene names	RBBP8, CTIP
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 8 (RBBP-8) (CtBP-interacting protein) (CtIP) (Retinoblastoma-interacting protein and myosin-like) (RIM).

P85B_HUMAN
NC score	0.053945 (rank : 134)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	106	Target Neighborhood Hits	543	Shared Neighborhood Hits	19
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

CU013_HUMAN
NC score	0.053877 (rank : 135)	θ value	0.813845 (rank : 50)
Query Neighborhood Hits	106	Target Neighborhood Hits	405	Shared Neighborhood Hits	18
SwissProt Accessions	O95447	Gene names	C21orf13
Domain Architecture
Description	Protein C21orf13.

APS_HUMAN
NC score	0.053765 (rank : 136)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	106	Target Neighborhood Hits	162	Shared Neighborhood Hits	3
SwissProt Accessions	O14492	Gene names	APS
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

RASA2_HUMAN
NC score	0.053320 (rank : 137)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	106	Target Neighborhood Hits	157	Shared Neighborhood Hits	45
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

CCD46_HUMAN
NC score	0.053243 (rank : 138)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	106	Target Neighborhood Hits	1430	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

HSH2D_MOUSE
NC score	0.053188 (rank : 139)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	106	Target Neighborhood Hits	124	Shared Neighborhood Hits	3
SwissProt Accessions	Q6VYH9, Q52KL3	Gene names	Hsh2d, Alx
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

SH3K1_MOUSE
NC score	0.052093 (rank : 140)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	106	Target Neighborhood Hits	332	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

DBNL_HUMAN
NC score	0.051979 (rank : 141)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	106	Target Neighborhood Hits	244	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

VAV2_HUMAN
NC score	0.051954 (rank : 142)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	106	Target Neighborhood Hits	453	Shared Neighborhood Hits	14
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

CCD45_MOUSE
NC score	0.051928 (rank : 143)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	106	Target Neighborhood Hits	663	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

SHE_MOUSE
NC score	0.051884 (rank : 144)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	106	Target Neighborhood Hits	169	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BSD5, Q3TZT0	Gene names	She
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

CCD21_HUMAN
NC score	0.051866 (rank : 145)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	106	Target Neighborhood Hits	1228	Shared Neighborhood Hits	26
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

TEX15_HUMAN
NC score	0.051570 (rank : 146)	θ value	0.163984 (rank : 33)
Query Neighborhood Hits	106	Target Neighborhood Hits	174	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BXT5	Gene names	TEX15
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 15 protein.

SH3K1_HUMAN
NC score	0.051510 (rank : 147)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	106	Target Neighborhood Hits	341	Shared Neighborhood Hits	9
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

SEGN_HUMAN
NC score	0.051453 (rank : 148)	θ value	2.36792 (rank : 67)
Query Neighborhood Hits	106	Target Neighborhood Hits	96	Shared Neighborhood Hits	6
SwissProt Accessions	O76038, Q5VV44, Q96QV7, Q9UJF6	Gene names	SCGN, SECRET
Domain Architecture
Description	Secretagogin.

NCK1_HUMAN
NC score	0.051435 (rank : 149)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	106	Target Neighborhood Hits	312	Shared Neighborhood Hits	7
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

SHE_HUMAN
NC score	0.051203 (rank : 150)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	106	Target Neighborhood Hits	164	Shared Neighborhood Hits	5
SwissProt Accessions	Q5VZ18, Q8TEQ5	Gene names	SHE
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

MAP1B_HUMAN
NC score	0.050943 (rank : 151)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	106	Target Neighborhood Hits	903	Shared Neighborhood Hits	17
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

CRKL_MOUSE
NC score	0.050609 (rank : 152)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	106	Target Neighborhood Hits	307	Shared Neighborhood Hits	7
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

CCD46_MOUSE
NC score	0.050465 (rank : 153)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	106	Target Neighborhood Hits	1405	Shared Neighborhood Hits	26
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

VAV_MOUSE
NC score	0.050427 (rank : 154)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	106	Target Neighborhood Hits	430	Shared Neighborhood Hits	14
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

AKAP9_HUMAN
NC score	0.049414 (rank : 155)	θ value	0.0148317 (rank : 22)
Query Neighborhood Hits	106	Target Neighborhood Hits	1710	Shared Neighborhood Hits	30
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

CCD11_HUMAN
NC score	0.047034 (rank : 156)	θ value	1.38821 (rank : 58)
Query Neighborhood Hits	106	Target Neighborhood Hits	822	Shared Neighborhood Hits	23
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

KPCG_MOUSE
NC score	0.042138 (rank : 157)	θ value	0.279714 (rank : 38)
Query Neighborhood Hits	106	Target Neighborhood Hits	1123	Shared Neighborhood Hits	58
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

KPCG_HUMAN
NC score	0.041722 (rank : 158)	θ value	0.47712 (rank : 44)
Query Neighborhood Hits	106	Target Neighborhood Hits	1126	Shared Neighborhood Hits	58
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

KPCA_MOUSE
NC score	0.039970 (rank : 159)	θ value	0.0961366 (rank : 29)
Query Neighborhood Hits	106	Target Neighborhood Hits	1067	Shared Neighborhood Hits	60
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KPCB_MOUSE
NC score	0.038766 (rank : 160)	θ value	1.81305 (rank : 64)
Query Neighborhood Hits	106	Target Neighborhood Hits	1117	Shared Neighborhood Hits	60
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCB_HUMAN
NC score	0.038322 (rank : 161)	θ value	1.81305 (rank : 63)
Query Neighborhood Hits	106	Target Neighborhood Hits	1121	Shared Neighborhood Hits	60
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCA_HUMAN
NC score	0.038150 (rank : 162)	θ value	0.21417 (rank : 36)
Query Neighborhood Hits	106	Target Neighborhood Hits	1070	Shared Neighborhood Hits	59
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KTN1_MOUSE
NC score	0.037256 (rank : 163)	θ value	2.36792 (rank : 66)
Query Neighborhood Hits	106	Target Neighborhood Hits	1324	Shared Neighborhood Hits	24
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

KTN1_HUMAN
NC score	0.036501 (rank : 164)	θ value	1.06291 (rank : 52)
Query Neighborhood Hits	106	Target Neighborhood Hits	1197	Shared Neighborhood Hits	22
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

KNTC2_MOUSE
NC score	0.035313 (rank : 165)	θ value	0.47712 (rank : 43)
Query Neighborhood Hits	106	Target Neighborhood Hits	692	Shared Neighborhood Hits	19
SwissProt Accessions	Q9D0F1, Q3TQT6, Q3UWM5, Q99P70	Gene names	Kntc2, Hec1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (Kinetochore-associated protein 2).

SYNE1_HUMAN
NC score	0.030622 (rank : 166)	θ value	3.0926 (rank : 75)
Query Neighborhood Hits	106	Target Neighborhood Hits	1484	Shared Neighborhood Hits	30
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

MYH1_HUMAN
NC score	0.025821 (rank : 167)	θ value	1.06291 (rank : 53)
Query Neighborhood Hits	106	Target Neighborhood Hits	1478	Shared Neighborhood Hits	24
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

MYH2_HUMAN
NC score	0.025021 (rank : 168)	θ value	0.47712 (rank : 45)
Query Neighborhood Hits	106	Target Neighborhood Hits	1491	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

CYLD_MOUSE
NC score	0.023246 (rank : 169)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	106	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q80TQ2, Q80VB3, Q8BXZ3, Q8BYL9, Q8CGB0	Gene names	Cyld, Cyld1, Kiaa0849
Domain Architecture	No domain graphic available
Description	Probable ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.1.2.15) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD) (Deubiquitinating enzyme CYLD).

KNTC2_HUMAN
NC score	0.022713 (rank : 170)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	106	Target Neighborhood Hits	673	Shared Neighborhood Hits	18
SwissProt Accessions	O14777, Q6PJX2	Gene names	KNTC2, HEC, HEC1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cancer protein) (Retinoblastoma-associated protein HEC).

MCM8_HUMAN
NC score	0.022701 (rank : 171)	θ value	1.38821 (rank : 59)
Query Neighborhood Hits	106	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UJA3, Q495R4, Q495R7, Q86US4, Q969I5	Gene names	MCM8, C20orf154
Domain Architecture
Description	DNA replication licensing factor MCM8 (Minichromosome maintenance 8).

MYH1_MOUSE
NC score	0.022524 (rank : 172)	θ value	3.0926 (rank : 72)
Query Neighborhood Hits	106	Target Neighborhood Hits	1461	Shared Neighborhood Hits	24
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

CYLD_HUMAN
NC score	0.022137 (rank : 173)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	106	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NQC7, O94934, Q7L3N6, Q96EH0, Q9NZX9	Gene names	CYLD, CYLD1, KIAA0849
Domain Architecture	No domain graphic available
Description	Probable ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.1.2.15) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD) (Deubiquitinating enzyme CYLD).

TF2LY_HUMAN
NC score	0.020190 (rank : 174)	θ value	1.38821 (rank : 60)
Query Neighborhood Hits	106	Target Neighborhood Hits	90	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IUE0	Gene names	TGIF2LY, TGIFLY
Domain Architecture
Description	Homeobox protein TGIF2LY (TGFB-induced factor 2-like protein, Y- linked) (TGF(beta)induced transcription factor 2-like protein) (TGIF- like on the Y).

RASF8_HUMAN
NC score	0.019779 (rank : 175)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	106	Target Neighborhood Hits	469	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NHQ8, O95647, Q5SCI2, Q76KB6	Gene names	RASSF8, C12orf2
Domain Architecture
Description	Ras association domain-containing protein 8 (Carcinoma-associated protein HOJ-1).

NCOR2_HUMAN
NC score	0.018339 (rank : 176)	θ value	4.03905 (rank : 79)
Query Neighborhood Hits	106	Target Neighborhood Hits	870	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

HAP1_HUMAN
NC score	0.018003 (rank : 177)	θ value	3.0926 (rank : 71)
Query Neighborhood Hits	106	Target Neighborhood Hits	606	Shared Neighborhood Hits	18
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

ROCK2_HUMAN
NC score	0.017941 (rank : 178)	θ value	4.03905 (rank : 81)
Query Neighborhood Hits	106	Target Neighborhood Hits	2073	Shared Neighborhood Hits	33
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

EFHC1_HUMAN
NC score	0.017939 (rank : 179)	θ value	5.27518 (rank : 84)
Query Neighborhood Hits	106	Target Neighborhood Hits	61	Shared Neighborhood Hits	5
SwissProt Accessions	Q5JVL4, Q5XKM4, Q6E1U7, Q6E1U8, Q8WUL2, Q9NVW6	Gene names	EFHC1
Domain Architecture	No domain graphic available
Description	EF-hand domain-containing protein 1.

TEC_HUMAN
NC score	0.017104 (rank : 180)	θ value	1.06291 (rank : 56)
Query Neighborhood Hits	106	Target Neighborhood Hits	1006	Shared Neighborhood Hits	18
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

TAF3_MOUSE
NC score	0.017032 (rank : 181)	θ value	4.03905 (rank : 82)
Query Neighborhood Hits	106	Target Neighborhood Hits	463	Shared Neighborhood Hits	8
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TEC_MOUSE
NC score	0.016550 (rank : 182)	θ value	1.81305 (rank : 65)
Query Neighborhood Hits	106	Target Neighborhood Hits	1006	Shared Neighborhood Hits	18
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

PLSI_HUMAN
NC score	0.016231 (rank : 183)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	106	Target Neighborhood Hits	209	Shared Neighborhood Hits	14
SwissProt Accessions	Q14651	Gene names	PLS1
Domain Architecture
Description	Plastin-1 (I-plastin) (Intestine-specific plastin).

ARNT2_HUMAN
NC score	0.015555 (rank : 184)	θ value	1.81305 (rank : 61)
Query Neighborhood Hits	106	Target Neighborhood Hits	109	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT2_MOUSE
NC score	0.015514 (rank : 185)	θ value	1.81305 (rank : 62)
Query Neighborhood Hits	106	Target Neighborhood Hits	115	Shared Neighborhood Hits	3
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

LETM1_MOUSE
NC score	0.014086 (rank : 186)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	106	Target Neighborhood Hits	240	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z2I0, Q5PQC5, Q7TMK8, Q80ZX6, Q8CGJ3, Q8K5E5	Gene names	Letm1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

MACF1_MOUSE
NC score	0.013868 (rank : 187)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	106	Target Neighborhood Hits	1313	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

EFHC1_MOUSE
NC score	0.012829 (rank : 188)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	106	Target Neighborhood Hits	65	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D9T8	Gene names	Efhc1
Domain Architecture	No domain graphic available
Description	EF-hand domain-containing protein 1.

DUS2L_MOUSE
NC score	0.011593 (rank : 189)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	106	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D7B1, Q6PDX2	Gene names	Dus2l
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 2-like (EC 1.-.-.-).

REV1_MOUSE
NC score	0.009103 (rank : 190)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	106	Target Neighborhood Hits	67	Shared Neighborhood Hits	2
SwissProt Accessions	Q920Q2, Q9QXV2	Gene names	Rev1l, Rev1
Domain Architecture	No domain graphic available
Description	DNA repair protein REV1 (EC 2.7.7.-) (Rev1-like terminal deoxycytidyl transferase).

MPDZ_HUMAN
NC score	0.007966 (rank : 191)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	106	Target Neighborhood Hits	261	Shared Neighborhood Hits	4
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

MPDZ_MOUSE
NC score	0.007617 (rank : 192)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	106	Target Neighborhood Hits	298	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

DUOX1_HUMAN
NC score	0.007606 (rank : 193)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	106	Target Neighborhood Hits	172	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NRD9, Q6ZMB3, Q6ZR09, Q9NZC1	Gene names	DUOX1, DUOX, LNOX1, THOX1
Domain Architecture	No domain graphic available
Description	Dual oxidase 1 precursor (EC 1.6.3.1) (EC 1.11.1.-) (NADPH thyroid oxidase 1) (Thyroid oxidase 1) (Large NOX 1) (Long NOX 1).

S10A5_MOUSE
NC score	0.007098 (rank : 194)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	106	Target Neighborhood Hits	54	Shared Neighborhood Hits	2
SwissProt Accessions	P63084, O88945, P82540	Gene names	S100a5, S100d
Domain Architecture	No domain graphic available
Description	Protein S100-A5 (S100 calcium-binding protein A5) (Protein S-100D).