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Network neighborhood for query Sequence : CYLD_MOUSE

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CYLD_MOUSE
SwissProt Accessions	Q80TQ2, Q80VB3, Q8BXZ3, Q8BYL9, Q8CGB0	Gene names	Cyld, Cyld1, Kiaa0849
Domain Architecture	No domain graphic available
Description	Probable ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.1.2.15) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD) (Deubiquitinating enzyme CYLD).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CYLD_HUMAN
θ value	0 (rank : 1)	NC score	0.991419 (rank : 2)
Query Neighborhood Hits	42	Target Neighborhood Hits	62	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NQC7, O94934, Q7L3N6, Q96EH0, Q9NZX9	Gene names	CYLD, CYLD1, KIAA0849
Domain Architecture	No domain graphic available
Description	Probable ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.1.2.15) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD) (Deubiquitinating enzyme CYLD).

CYLD_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	42	Target Neighborhood Hits	42	Shared Neighborhood Hits	42
SwissProt Accessions	Q80TQ2, Q80VB3, Q8BXZ3, Q8BYL9, Q8CGB0	Gene names	Cyld, Cyld1, Kiaa0849
Domain Architecture	No domain graphic available
Description	Probable ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.1.2.15) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD) (Deubiquitinating enzyme CYLD).

CYLN2_HUMAN
θ value	3.19293e-05 (rank : 3)	NC score	0.127510 (rank : 9)
Query Neighborhood Hits	42	Target Neighborhood Hits	1004	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

CLR59_HUMAN
θ value	0.000121331 (rank : 4)	NC score	0.235160 (rank : 3)
Query Neighborhood Hits	42	Target Neighborhood Hits	163	Shared Neighborhood Hits	16
SwissProt Accessions	Q96DZ5, Q8WWL1, Q96C99, Q9UFT7	Gene names	CLIPR59
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa protein).

CYLN2_MOUSE
θ value	0.000270298 (rank : 5)	NC score	0.126127 (rank : 10)
Query Neighborhood Hits	42	Target Neighborhood Hits	1002	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

DYNA_HUMAN
θ value	0.00869519 (rank : 6)	NC score	0.098726 (rank : 13)
Query Neighborhood Hits	42	Target Neighborhood Hits	1194	Shared Neighborhood Hits	18
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

DYNA_MOUSE
θ value	0.00869519 (rank : 7)	NC score	0.100380 (rank : 11)
Query Neighborhood Hits	42	Target Neighborhood Hits	1084	Shared Neighborhood Hits	18
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

REST_MOUSE
θ value	0.0113563 (rank : 8)	NC score	0.086774 (rank : 14)
Query Neighborhood Hits	42	Target Neighborhood Hits	1506	Shared Neighborhood Hits	17
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

REST_HUMAN
θ value	0.0148317 (rank : 9)	NC score	0.084475 (rank : 15)
Query Neighborhood Hits	42	Target Neighborhood Hits	1605	Shared Neighborhood Hits	17
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

CEP35_HUMAN
θ value	0.0563607 (rank : 10)	NC score	0.140243 (rank : 8)
Query Neighborhood Hits	42	Target Neighborhood Hits	811	Shared Neighborhood Hits	17
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

ASXL1_HUMAN
θ value	0.0961366 (rank : 11)	NC score	0.070402 (rank : 16)
Query Neighborhood Hits	42	Target Neighborhood Hits	260	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

TBCB_HUMAN
θ value	0.125558 (rank : 12)	NC score	0.218825 (rank : 4)
Query Neighborhood Hits	42	Target Neighborhood Hits	20	Shared Neighborhood Hits	16
SwissProt Accessions	Q99426, O00111, O00674, O14728	Gene names	CKAP1, CG22
Domain Architecture
Description	Tubulin-specific chaperone B (Tubulin folding cofactor B) (Cytoskeleton-associated protein 1) (Cytoskeleton-associated protein CKAPI).

TBCB_MOUSE
θ value	0.163984 (rank : 13)	NC score	0.206949 (rank : 5)
Query Neighborhood Hits	42	Target Neighborhood Hits	21	Shared Neighborhood Hits	16
SwissProt Accessions	Q9D1E6, Q9CWR6, Q9DCZ6	Gene names	Ckap1
Domain Architecture	No domain graphic available
Description	Tubulin-specific chaperone B (Tubulin folding cofactor B) (Cytoskeleton-associated protein 1) (Cytoskeleton-associated protein CKAPI).

JAD1C_HUMAN
θ value	0.365318 (rank : 14)	NC score	0.062576 (rank : 19)
Query Neighborhood Hits	42	Target Neighborhood Hits	187	Shared Neighborhood Hits	6
SwissProt Accessions	P41229	Gene names	SMCX, DXS1272E, JARID1C, XE169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (Protein SmcX) (Protein Xe169).

JAD1C_MOUSE
θ value	0.365318 (rank : 15)	NC score	0.062745 (rank : 18)
Query Neighborhood Hits	42	Target Neighborhood Hits	164	Shared Neighborhood Hits	6
SwissProt Accessions	P41230, O54995, Q9CVI4, Q9D0C3, Q9QVR8, Q9R039	Gene names	Smcx, Jarid1c, Xe169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (SmcX protein) (Xe169 protein).

JAD1D_HUMAN
θ value	0.47712 (rank : 16)	NC score	0.061445 (rank : 20)
Query Neighborhood Hits	42	Target Neighborhood Hits	147	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BY66, Q92509, Q92809, Q9HCU1	Gene names	SMCY, HY, HYA, JARID1D, KIAA0234
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

TBCE_MOUSE
θ value	1.06291 (rank : 17)	NC score	0.099884 (rank : 12)
Query Neighborhood Hits	42	Target Neighborhood Hits	122	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CIV8	Gene names	Tbce
Domain Architecture	No domain graphic available
Description	Tubulin-specific chaperone E (Tubulin-folding cofactor E).

RSNL2_HUMAN
θ value	1.38821 (rank : 18)	NC score	0.162921 (rank : 7)
Query Neighborhood Hits	42	Target Neighborhood Hits	136	Shared Neighborhood Hits	17
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

JAD1D_MOUSE
θ value	1.81305 (rank : 19)	NC score	0.057157 (rank : 21)
Query Neighborhood Hits	42	Target Neighborhood Hits	228	Shared Neighborhood Hits	6
SwissProt Accessions	Q62240, Q9QVR9, Q9R040	Gene names	Smcy, Hya, Jarid1d
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

PITM2_MOUSE
θ value	1.81305 (rank : 20)	NC score	0.041797 (rank : 23)
Query Neighborhood Hits	42	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZPQ6, Q9R1P5	Gene names	Pitpnm2, Kiaa1457, Nir3
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 2 (Phosphatidylinositol transfer protein, membrane-associated 2) (Pyk2 N-terminal domain-interacting receptor 3) (NIR-3) (Drosophila retinal degeneration B homolog 2) (RdgB2).

RBP2_MOUSE
θ value	2.36792 (rank : 21)	NC score	0.022967 (rank : 31)
Query Neighborhood Hits	42	Target Neighborhood Hits	232	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ERU9, Q61992, Q8C9K9	Gene names	Ranbp2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2 (RanBP2).

RSNL2_MOUSE
θ value	2.36792 (rank : 22)	NC score	0.167336 (rank : 6)
Query Neighborhood Hits	42	Target Neighborhood Hits	129	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CI96, Q8BW09, Q921Q4, Q9D2S6	Gene names	Rsnl2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

WNK2_HUMAN
θ value	2.36792 (rank : 23)	NC score	0.003969 (rank : 42)
Query Neighborhood Hits	42	Target Neighborhood Hits	1407	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

AZI1_HUMAN
θ value	3.0926 (rank : 24)	NC score	0.030137 (rank : 28)
Query Neighborhood Hits	42	Target Neighborhood Hits	1000	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

PLCD1_HUMAN
θ value	3.0926 (rank : 25)	NC score	0.028344 (rank : 29)
Query Neighborhood Hits	42	Target Neighborhood Hits	93	Shared Neighborhood Hits	4
SwissProt Accessions	P51178	Gene names	PLCD1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

RBP22_HUMAN
θ value	3.0926 (rank : 26)	NC score	0.035009 (rank : 27)
Query Neighborhood Hits	42	Target Neighborhood Hits	165	Shared Neighborhood Hits	5
SwissProt Accessions	Q53T03, Q53QN2, Q59GM7	Gene names	RANBP2L2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 2 (RanBP2L2).

RGPD8_HUMAN
θ value	3.0926 (rank : 27)	NC score	0.035189 (rank : 26)
Query Neighborhood Hits	42	Target Neighborhood Hits	135	Shared Neighborhood Hits	5
SwissProt Accessions	Q99666	Gene names	RGPD8, RANBP2L1
Domain Architecture	No domain graphic available
Description	RANBP2-like and GRIP domain-containing protein 8 (Ran-binding protein 2-like 1) (RanBP2L1) (Sperm membrane protein BS-63).

SPHK2_HUMAN
θ value	3.0926 (rank : 28)	NC score	0.022636 (rank : 32)
Query Neighborhood Hits	42	Target Neighborhood Hits	81	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NRA0, Q9BRN1, Q9H0Q2, Q9NWU7	Gene names	SPHK2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

UB17L_HUMAN
θ value	3.0926 (rank : 29)	NC score	0.020643 (rank : 34)
Query Neighborhood Hits	42	Target Neighborhood Hits	83	Shared Neighborhood Hits	3
SwissProt Accessions	Q7RTZ2	Gene names	USP17L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 17-like protein (EC 3.1.2.15) (Ubiquitin thioesterase 17-like) (Ubiquitin-specific-processing protease 17-like) (Deubiquitinating enzyme 17-like).

TR13C_MOUSE
θ value	4.03905 (rank : 30)	NC score	0.037277 (rank : 24)
Query Neighborhood Hits	42	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D8D0	Gene names	Tnfrsf13c, Baffr, Bcmd, Br3
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 13C (B cell- activating factor receptor) (BAFF receptor) (BAFF-R) (BLyS receptor 3) (B-cell maturation defect).

CUZD1_MOUSE
θ value	5.27518 (rank : 31)	NC score	0.015901 (rank : 36)
Query Neighborhood Hits	42	Target Neighborhood Hits	91	Shared Neighborhood Hits	3
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

KI13B_HUMAN
θ value	5.27518 (rank : 32)	NC score	0.043573 (rank : 22)
Query Neighborhood Hits	42	Target Neighborhood Hits	492	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NQT8, O75134, Q9BYJ6	Gene names	KIF13B, GAKIN, KIAA0639
Domain Architecture
Description	Kinesin-like protein KIF13B (Kinesin-like protein GAKIN).

TRPC2_MOUSE
θ value	5.27518 (rank : 33)	NC score	0.010279 (rank : 38)
Query Neighborhood Hits	42	Target Neighborhood Hits	84	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R244, Q9ES59, Q9ES60, Q9R243	Gene names	Trpc2, Trp2, Trrp2
Domain Architecture
Description	Short transient receptor potential channel 2 (TrpC2) (mTrp2).

CPN2_MOUSE
θ value	6.88961 (rank : 34)	NC score	0.003846 (rank : 43)
Query Neighborhood Hits	42	Target Neighborhood Hits	291	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBB9, Q8R113	Gene names	Cpn2
Domain Architecture	No domain graphic available
Description	Carboxypeptidase N subunit 2 precursor (Carboxypeptidase N polypeptide 2) (Carboxypeptidase N 83 kDa chain) (Carboxypeptidase N regulatory subunit) (Carboxypeptidase N large subunit).

PLCD1_MOUSE
θ value	6.88961 (rank : 35)	NC score	0.023246 (rank : 30)
Query Neighborhood Hits	42	Target Neighborhood Hits	106	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R3B1	Gene names	Plcd1, Plcd
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

COG2_HUMAN
θ value	8.99809 (rank : 36)	NC score	0.021069 (rank : 33)
Query Neighborhood Hits	42	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q14746	Gene names	COG2, LDLC
Domain Architecture
Description	Conserved oligomeric Golgi complex component 2 (Low density lipoprotein receptor defect C-complementing protein).

DGCR8_MOUSE
θ value	8.99809 (rank : 37)	NC score	0.012957 (rank : 37)
Query Neighborhood Hits	42	Target Neighborhood Hits	70	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EQM6	Gene names	Dgcr8
Domain Architecture	No domain graphic available
Description	DGCR8 protein (DiGeorge syndrome critical region 8 homolog) (Gy1).

ETV6_MOUSE
θ value	8.99809 (rank : 38)	NC score	0.007723 (rank : 40)
Query Neighborhood Hits	42	Target Neighborhood Hits	103	Shared Neighborhood Hits	2
SwissProt Accessions	P97360	Gene names	Etv6, Tel, Tel1
Domain Architecture
Description	Transcription factor ETV6 (ETS-related protein Tel1) (Tel) (ETS translocation variant 6).

FGD4_HUMAN
θ value	8.99809 (rank : 39)	NC score	0.007275 (rank : 41)
Query Neighborhood Hits	42	Target Neighborhood Hits	219	Shared Neighborhood Hits	3
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

IP6K1_HUMAN
θ value	8.99809 (rank : 40)	NC score	0.009439 (rank : 39)
Query Neighborhood Hits	42	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q92551, Q7L3I7, Q96E38	Gene names	IHPK1, IP6K1, KIAA0263
Domain Architecture	No domain graphic available
Description	Inositol hexaphosphate kinase 1 (EC 2.7.4.21) (InsP6 kinase 1) (Inositol hexakisphosphate kinase 1).

MKL1_MOUSE
θ value	8.99809 (rank : 41)	NC score	0.016337 (rank : 35)
Query Neighborhood Hits	42	Target Neighborhood Hits	667	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

SETBP_HUMAN
θ value	8.99809 (rank : 42)	NC score	0.036038 (rank : 25)
Query Neighborhood Hits	42	Target Neighborhood Hits	305	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

TBCE_HUMAN
θ value	θ > 10 (rank : 43)	NC score	0.063753 (rank : 17)
Query Neighborhood Hits	42	Target Neighborhood Hits	141	Shared Neighborhood Hits	14
SwissProt Accessions	Q15813	Gene names	TBCE
Domain Architecture	No domain graphic available
Description	Tubulin-specific chaperone E (Tubulin-folding cofactor E).

Hits sorted by NC score

CYLD_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	42	Target Neighborhood Hits	42	Shared Neighborhood Hits	42
SwissProt Accessions	Q80TQ2, Q80VB3, Q8BXZ3, Q8BYL9, Q8CGB0	Gene names	Cyld, Cyld1, Kiaa0849
Domain Architecture	No domain graphic available
Description	Probable ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.1.2.15) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD) (Deubiquitinating enzyme CYLD).

CYLD_HUMAN
NC score	0.991419 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	42	Target Neighborhood Hits	62	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NQC7, O94934, Q7L3N6, Q96EH0, Q9NZX9	Gene names	CYLD, CYLD1, KIAA0849
Domain Architecture	No domain graphic available
Description	Probable ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.1.2.15) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD) (Deubiquitinating enzyme CYLD).

CLR59_HUMAN
NC score	0.235160 (rank : 3)	θ value	0.000121331 (rank : 4)
Query Neighborhood Hits	42	Target Neighborhood Hits	163	Shared Neighborhood Hits	16
SwissProt Accessions	Q96DZ5, Q8WWL1, Q96C99, Q9UFT7	Gene names	CLIPR59
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa protein).

TBCB_HUMAN
NC score	0.218825 (rank : 4)	θ value	0.125558 (rank : 12)
Query Neighborhood Hits	42	Target Neighborhood Hits	20	Shared Neighborhood Hits	16
SwissProt Accessions	Q99426, O00111, O00674, O14728	Gene names	CKAP1, CG22
Domain Architecture
Description	Tubulin-specific chaperone B (Tubulin folding cofactor B) (Cytoskeleton-associated protein 1) (Cytoskeleton-associated protein CKAPI).

TBCB_MOUSE
NC score	0.206949 (rank : 5)	θ value	0.163984 (rank : 13)
Query Neighborhood Hits	42	Target Neighborhood Hits	21	Shared Neighborhood Hits	16
SwissProt Accessions	Q9D1E6, Q9CWR6, Q9DCZ6	Gene names	Ckap1
Domain Architecture	No domain graphic available
Description	Tubulin-specific chaperone B (Tubulin folding cofactor B) (Cytoskeleton-associated protein 1) (Cytoskeleton-associated protein CKAPI).

RSNL2_MOUSE
NC score	0.167336 (rank : 6)	θ value	2.36792 (rank : 22)
Query Neighborhood Hits	42	Target Neighborhood Hits	129	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CI96, Q8BW09, Q921Q4, Q9D2S6	Gene names	Rsnl2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

RSNL2_HUMAN
NC score	0.162921 (rank : 7)	θ value	1.38821 (rank : 18)
Query Neighborhood Hits	42	Target Neighborhood Hits	136	Shared Neighborhood Hits	17
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

CEP35_HUMAN
NC score	0.140243 (rank : 8)	θ value	0.0563607 (rank : 10)
Query Neighborhood Hits	42	Target Neighborhood Hits	811	Shared Neighborhood Hits	17
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

CYLN2_HUMAN
NC score	0.127510 (rank : 9)	θ value	3.19293e-05 (rank : 3)
Query Neighborhood Hits	42	Target Neighborhood Hits	1004	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

CYLN2_MOUSE
NC score	0.126127 (rank : 10)	θ value	0.000270298 (rank : 5)
Query Neighborhood Hits	42	Target Neighborhood Hits	1002	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

DYNA_MOUSE
NC score	0.100380 (rank : 11)	θ value	0.00869519 (rank : 7)
Query Neighborhood Hits	42	Target Neighborhood Hits	1084	Shared Neighborhood Hits	18
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

TBCE_MOUSE
NC score	0.099884 (rank : 12)	θ value	1.06291 (rank : 17)
Query Neighborhood Hits	42	Target Neighborhood Hits	122	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CIV8	Gene names	Tbce
Domain Architecture	No domain graphic available
Description	Tubulin-specific chaperone E (Tubulin-folding cofactor E).

DYNA_HUMAN
NC score	0.098726 (rank : 13)	θ value	0.00869519 (rank : 6)
Query Neighborhood Hits	42	Target Neighborhood Hits	1194	Shared Neighborhood Hits	18
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

REST_MOUSE
NC score	0.086774 (rank : 14)	θ value	0.0113563 (rank : 8)
Query Neighborhood Hits	42	Target Neighborhood Hits	1506	Shared Neighborhood Hits	17
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

REST_HUMAN
NC score	0.084475 (rank : 15)	θ value	0.0148317 (rank : 9)
Query Neighborhood Hits	42	Target Neighborhood Hits	1605	Shared Neighborhood Hits	17
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

ASXL1_HUMAN
NC score	0.070402 (rank : 16)	θ value	0.0961366 (rank : 11)
Query Neighborhood Hits	42	Target Neighborhood Hits	260	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

TBCE_HUMAN
NC score	0.063753 (rank : 17)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	42	Target Neighborhood Hits	141	Shared Neighborhood Hits	14
SwissProt Accessions	Q15813	Gene names	TBCE
Domain Architecture	No domain graphic available
Description	Tubulin-specific chaperone E (Tubulin-folding cofactor E).

JAD1C_MOUSE
NC score	0.062745 (rank : 18)	θ value	0.365318 (rank : 15)
Query Neighborhood Hits	42	Target Neighborhood Hits	164	Shared Neighborhood Hits	6
SwissProt Accessions	P41230, O54995, Q9CVI4, Q9D0C3, Q9QVR8, Q9R039	Gene names	Smcx, Jarid1c, Xe169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (SmcX protein) (Xe169 protein).

JAD1C_HUMAN
NC score	0.062576 (rank : 19)	θ value	0.365318 (rank : 14)
Query Neighborhood Hits	42	Target Neighborhood Hits	187	Shared Neighborhood Hits	6
SwissProt Accessions	P41229	Gene names	SMCX, DXS1272E, JARID1C, XE169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (Protein SmcX) (Protein Xe169).

JAD1D_HUMAN
NC score	0.061445 (rank : 20)	θ value	0.47712 (rank : 16)
Query Neighborhood Hits	42	Target Neighborhood Hits	147	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BY66, Q92509, Q92809, Q9HCU1	Gene names	SMCY, HY, HYA, JARID1D, KIAA0234
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

JAD1D_MOUSE
NC score	0.057157 (rank : 21)	θ value	1.81305 (rank : 19)
Query Neighborhood Hits	42	Target Neighborhood Hits	228	Shared Neighborhood Hits	6
SwissProt Accessions	Q62240, Q9QVR9, Q9R040	Gene names	Smcy, Hya, Jarid1d
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

KI13B_HUMAN
NC score	0.043573 (rank : 22)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	42	Target Neighborhood Hits	492	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NQT8, O75134, Q9BYJ6	Gene names	KIF13B, GAKIN, KIAA0639
Domain Architecture
Description	Kinesin-like protein KIF13B (Kinesin-like protein GAKIN).

PITM2_MOUSE
NC score	0.041797 (rank : 23)	θ value	1.81305 (rank : 20)
Query Neighborhood Hits	42	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZPQ6, Q9R1P5	Gene names	Pitpnm2, Kiaa1457, Nir3
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 2 (Phosphatidylinositol transfer protein, membrane-associated 2) (Pyk2 N-terminal domain-interacting receptor 3) (NIR-3) (Drosophila retinal degeneration B homolog 2) (RdgB2).

TR13C_MOUSE
NC score	0.037277 (rank : 24)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	42	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D8D0	Gene names	Tnfrsf13c, Baffr, Bcmd, Br3
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 13C (B cell- activating factor receptor) (BAFF receptor) (BAFF-R) (BLyS receptor 3) (B-cell maturation defect).

SETBP_HUMAN
NC score	0.036038 (rank : 25)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	42	Target Neighborhood Hits	305	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

RGPD8_HUMAN
NC score	0.035189 (rank : 26)	θ value	3.0926 (rank : 27)
Query Neighborhood Hits	42	Target Neighborhood Hits	135	Shared Neighborhood Hits	5
SwissProt Accessions	Q99666	Gene names	RGPD8, RANBP2L1
Domain Architecture	No domain graphic available
Description	RANBP2-like and GRIP domain-containing protein 8 (Ran-binding protein 2-like 1) (RanBP2L1) (Sperm membrane protein BS-63).

RBP22_HUMAN
NC score	0.035009 (rank : 27)	θ value	3.0926 (rank : 26)
Query Neighborhood Hits	42	Target Neighborhood Hits	165	Shared Neighborhood Hits	5
SwissProt Accessions	Q53T03, Q53QN2, Q59GM7	Gene names	RANBP2L2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 2 (RanBP2L2).

AZI1_HUMAN
NC score	0.030137 (rank : 28)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	42	Target Neighborhood Hits	1000	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

PLCD1_HUMAN
NC score	0.028344 (rank : 29)	θ value	3.0926 (rank : 25)
Query Neighborhood Hits	42	Target Neighborhood Hits	93	Shared Neighborhood Hits	4
SwissProt Accessions	P51178	Gene names	PLCD1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

PLCD1_MOUSE
NC score	0.023246 (rank : 30)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	42	Target Neighborhood Hits	106	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R3B1	Gene names	Plcd1, Plcd
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

RBP2_MOUSE
NC score	0.022967 (rank : 31)	θ value	2.36792 (rank : 21)
Query Neighborhood Hits	42	Target Neighborhood Hits	232	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ERU9, Q61992, Q8C9K9	Gene names	Ranbp2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2 (RanBP2).

SPHK2_HUMAN
NC score	0.022636 (rank : 32)	θ value	3.0926 (rank : 28)
Query Neighborhood Hits	42	Target Neighborhood Hits	81	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NRA0, Q9BRN1, Q9H0Q2, Q9NWU7	Gene names	SPHK2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

COG2_HUMAN
NC score	0.021069 (rank : 33)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	42	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q14746	Gene names	COG2, LDLC
Domain Architecture
Description	Conserved oligomeric Golgi complex component 2 (Low density lipoprotein receptor defect C-complementing protein).

UB17L_HUMAN
NC score	0.020643 (rank : 34)	θ value	3.0926 (rank : 29)
Query Neighborhood Hits	42	Target Neighborhood Hits	83	Shared Neighborhood Hits	3
SwissProt Accessions	Q7RTZ2	Gene names	USP17L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 17-like protein (EC 3.1.2.15) (Ubiquitin thioesterase 17-like) (Ubiquitin-specific-processing protease 17-like) (Deubiquitinating enzyme 17-like).

MKL1_MOUSE
NC score	0.016337 (rank : 35)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	42	Target Neighborhood Hits	667	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

CUZD1_MOUSE
NC score	0.015901 (rank : 36)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	42	Target Neighborhood Hits	91	Shared Neighborhood Hits	3
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

DGCR8_MOUSE
NC score	0.012957 (rank : 37)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	42	Target Neighborhood Hits	70	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EQM6	Gene names	Dgcr8
Domain Architecture	No domain graphic available
Description	DGCR8 protein (DiGeorge syndrome critical region 8 homolog) (Gy1).

TRPC2_MOUSE
NC score	0.010279 (rank : 38)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	42	Target Neighborhood Hits	84	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R244, Q9ES59, Q9ES60, Q9R243	Gene names	Trpc2, Trp2, Trrp2
Domain Architecture
Description	Short transient receptor potential channel 2 (TrpC2) (mTrp2).

IP6K1_HUMAN
NC score	0.009439 (rank : 39)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	42	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q92551, Q7L3I7, Q96E38	Gene names	IHPK1, IP6K1, KIAA0263
Domain Architecture	No domain graphic available
Description	Inositol hexaphosphate kinase 1 (EC 2.7.4.21) (InsP6 kinase 1) (Inositol hexakisphosphate kinase 1).

ETV6_MOUSE
NC score	0.007723 (rank : 40)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	42	Target Neighborhood Hits	103	Shared Neighborhood Hits	2
SwissProt Accessions	P97360	Gene names	Etv6, Tel, Tel1
Domain Architecture
Description	Transcription factor ETV6 (ETS-related protein Tel1) (Tel) (ETS translocation variant 6).

FGD4_HUMAN
NC score	0.007275 (rank : 41)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	42	Target Neighborhood Hits	219	Shared Neighborhood Hits	3
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

WNK2_HUMAN
NC score	0.003969 (rank : 42)	θ value	2.36792 (rank : 23)
Query Neighborhood Hits	42	Target Neighborhood Hits	1407	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

CPN2_MOUSE
NC score	0.003846 (rank : 43)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	42	Target Neighborhood Hits	291	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBB9, Q8R113	Gene names	Cpn2
Domain Architecture	No domain graphic available
Description	Carboxypeptidase N subunit 2 precursor (Carboxypeptidase N polypeptide 2) (Carboxypeptidase N 83 kDa chain) (Carboxypeptidase N regulatory subunit) (Carboxypeptidase N large subunit).