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Network neighborhood for query Sequence : PITM2_MOUSE

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PITM2_MOUSE
SwissProt Accessions	Q6ZPQ6, Q9R1P5	Gene names	Pitpnm2, Kiaa1457, Nir3
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 2 (Phosphatidylinositol transfer protein, membrane-associated 2) (Pyk2 N-terminal domain-interacting receptor 3) (NIR-3) (Drosophila retinal degeneration B homolog 2) (RdgB2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PITM1_HUMAN
θ value	0 (rank : 1)	NC score	0.972606 (rank : 4)
Query Neighborhood Hits	46	Target Neighborhood Hits	129	Shared Neighborhood Hits	16
SwissProt Accessions	O00562, Q6T7X3, Q8TBN3, Q9BZ73	Gene names	PITPNM1, DRES9, NIR2, PITPNM
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 1 (Phosphatidylinositol transfer protein, membrane-associated 1) (Pyk2 N-terminal domain-interacting receptor 2) (NIR-2) (Drosophila retinal degeneration B homolog).

PITM1_MOUSE
θ value	0 (rank : 2)	NC score	0.982944 (rank : 3)
Query Neighborhood Hits	46	Target Neighborhood Hits	69	Shared Neighborhood Hits	15
SwissProt Accessions	O35954	Gene names	Pitpnm1, Dres9, Mpt1, Nir2, Pitpnm
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 1 (Phosphatidylinositol transfer protein, membrane-associated 1) (PITPnm 1) (Mpt-1) (Pyk2 N-terminal domain-interacting receptor 2) (NIR-2) (Drosophila retinal degeneration B homolog 1) (RdgB1).

PITM2_HUMAN
θ value	0 (rank : 3)	NC score	0.994327 (rank : 2)
Query Neighborhood Hits	46	Target Neighborhood Hits	52	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BZ72, Q9P271	Gene names	PITPNM2, KIAA1457, NIR3
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 2 (Phosphatidylinositol transfer protein, membrane-associated 2) (Pyk2 N-terminal domain-interacting receptor 3) (NIR-3).

PITM2_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	46	Target Neighborhood Hits	46	Shared Neighborhood Hits	46
SwissProt Accessions	Q6ZPQ6, Q9R1P5	Gene names	Pitpnm2, Kiaa1457, Nir3
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 2 (Phosphatidylinositol transfer protein, membrane-associated 2) (Pyk2 N-terminal domain-interacting receptor 3) (NIR-3) (Drosophila retinal degeneration B homolog 2) (RdgB2).

PITM3_HUMAN
θ value	0 (rank : 5)	NC score	0.897424 (rank : 6)
Query Neighborhood Hits	46	Target Neighborhood Hits	30	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BZ71, Q59GH9, Q9NPQ4	Gene names	PITPNM3, NIR1
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 3 (Phosphatidylinositol transfer protein, membrane-associated 3) (Pyk2 N-terminal domain-interacting receptor 1) (NIR-1).

PITM3_MOUSE
θ value	0 (rank : 6)	NC score	0.899737 (rank : 5)
Query Neighborhood Hits	46	Target Neighborhood Hits	30	Shared Neighborhood Hits	11
SwissProt Accessions	Q3UHE1, Q3UH22, Q5RIT9	Gene names	Pitpnm3, Nir1
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 3 (Phosphatidylinositol transfer protein, membrane-associated 3) (Pyk2 N-terminal domain-interacting receptor 1) (NIR-1).

PIPNA_MOUSE
θ value	8.26713e-62 (rank : 7)	NC score	0.776446 (rank : 7)
Query Neighborhood Hits	46	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	P53810	Gene names	Pitpna, Pitpn
Domain Architecture
Description	Phosphatidylinositol transfer protein alpha isoform (PtdIns transfer protein alpha) (PtdInsTP) (PI-TP-alpha).

PIPNA_HUMAN
θ value	5.35859e-61 (rank : 8)	NC score	0.775340 (rank : 8)
Query Neighborhood Hits	46	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	Q00169	Gene names	PITPNA, PITPN
Domain Architecture
Description	Phosphatidylinositol transfer protein alpha isoform (PtdIns transfer protein alpha) (PtdInsTP) (PI-TP-alpha).

PIPNB_HUMAN
θ value	3.84025e-59 (rank : 9)	NC score	0.771167 (rank : 10)
Query Neighborhood Hits	46	Target Neighborhood Hits	15	Shared Neighborhood Hits	8
SwissProt Accessions	P48739, Q8N5W1	Gene names	PITPNB
Domain Architecture
Description	Phosphatidylinositol transfer protein beta isoform (PtdIns transfer protein beta) (PtdInsTP) (PI-TP-beta).

PIPNB_MOUSE
θ value	6.55044e-59 (rank : 10)	NC score	0.771354 (rank : 9)
Query Neighborhood Hits	46	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	P53811	Gene names	Pitpnb
Domain Architecture
Description	Phosphatidylinositol transfer protein beta isoform (PtdIns transfer protein beta) (PtdInsTP) (PI-TP-beta).

DDHD1_HUMAN
θ value	1.29631e-06 (rank : 11)	NC score	0.337168 (rank : 12)
Query Neighborhood Hits	46	Target Neighborhood Hits	40	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NEL9, Q8WVH3, Q96LL2, Q9C0F8	Gene names	DDHD1, KIAA1705
Domain Architecture
Description	Probable phospholipase DDHD1 (EC 3.1.1.-) (DDHD domain protein 1) (Phosphatidic acid-preferring phospholipase A1 homolog) (PA-PLA1).

DDHD1_MOUSE
θ value	1.69304e-06 (rank : 12)	NC score	0.349996 (rank : 11)
Query Neighborhood Hits	46	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	Q80YA3, Q8VEF2	Gene names	Ddhd1
Domain Architecture
Description	Probable phospholipase DDHD1 (EC 3.1.1.-) (DDHD domain protein 1) (Phosphatidic acid-preferring phospholipase A1 homolog) (PA-PLA1).

S23IP_MOUSE
θ value	1.09739e-05 (rank : 13)	NC score	0.283790 (rank : 14)
Query Neighborhood Hits	46	Target Neighborhood Hits	363	Shared Neighborhood Hits	11
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

S23IP_HUMAN
θ value	7.1131e-05 (rank : 14)	NC score	0.289572 (rank : 13)
Query Neighborhood Hits	46	Target Neighborhood Hits	134	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6Y8, Q8IXH5, Q9BUK5	Gene names	SEC23IP
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein (p125).

CYLD_HUMAN
θ value	0.00509761 (rank : 15)	NC score	0.058086 (rank : 15)
Query Neighborhood Hits	46	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NQC7, O94934, Q7L3N6, Q96EH0, Q9NZX9	Gene names	CYLD, CYLD1, KIAA0849
Domain Architecture	No domain graphic available
Description	Probable ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.1.2.15) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD) (Deubiquitinating enzyme CYLD).

LEO1_MOUSE
θ value	0.0961366 (rank : 16)	NC score	0.024820 (rank : 19)
Query Neighborhood Hits	46	Target Neighborhood Hits	946	Shared Neighborhood Hits	10
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

LEO1_HUMAN
θ value	0.47712 (rank : 17)	NC score	0.020593 (rank : 21)
Query Neighborhood Hits	46	Target Neighborhood Hits	958	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

TNF10_HUMAN
θ value	0.62314 (rank : 18)	NC score	0.025893 (rank : 18)
Query Neighborhood Hits	46	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	P50591	Gene names	TNFSF10, APO2L, TRAIL
Domain Architecture
Description	Tumor necrosis factor ligand superfamily member 10 (TNF-related apoptosis-inducing ligand) (Protein TRAIL) (Apo-2 ligand) (Apo-2L) (CD253 antigen).

AIPL1_HUMAN
θ value	0.813845 (rank : 19)	NC score	0.024274 (rank : 20)
Query Neighborhood Hits	46	Target Neighborhood Hits	113	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZN9, Q9H873, Q9NS10	Gene names	AIPL1
Domain Architecture
Description	Aryl-hydrocarbon-interacting protein-like 1.

STK10_MOUSE
θ value	0.813845 (rank : 20)	NC score	0.000321 (rank : 45)
Query Neighborhood Hits	46	Target Neighborhood Hits	2132	Shared Neighborhood Hits	12
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

ADDB_MOUSE
θ value	1.06291 (rank : 21)	NC score	0.012470 (rank : 24)
Query Neighborhood Hits	46	Target Neighborhood Hits	574	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

RIPK1_MOUSE
θ value	1.38821 (rank : 22)	NC score	0.003155 (rank : 42)
Query Neighborhood Hits	46	Target Neighborhood Hits	874	Shared Neighborhood Hits	4
SwissProt Accessions	Q60855, Q3U0J3, Q8CD90	Gene names	Ripk1, Rinp, Rip
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

SUHW4_HUMAN
θ value	1.38821 (rank : 23)	NC score	0.003805 (rank : 41)
Query Neighborhood Hits	46	Target Neighborhood Hits	860	Shared Neighborhood Hits	6
SwissProt Accessions	Q6N043, Q6MZM6, Q6N085, Q9H0U5, Q9HCI8, Q9NXS0	Gene names	SUHW4, KIAA1584
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

CYLD_MOUSE
θ value	1.81305 (rank : 24)	NC score	0.041797 (rank : 16)
Query Neighborhood Hits	46	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q80TQ2, Q80VB3, Q8BXZ3, Q8BYL9, Q8CGB0	Gene names	Cyld, Cyld1, Kiaa0849
Domain Architecture	No domain graphic available
Description	Probable ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.1.2.15) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD) (Deubiquitinating enzyme CYLD).

NRBP_HUMAN
θ value	1.81305 (rank : 25)	NC score	0.013726 (rank : 23)
Query Neighborhood Hits	46	Target Neighborhood Hits	448	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UHY1, Q53FZ5, Q96SU3	Gene names	NRBP1, BCON3, NRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding protein.

NRBP_MOUSE
θ value	1.81305 (rank : 26)	NC score	0.013832 (rank : 22)
Query Neighborhood Hits	46	Target Neighborhood Hits	442	Shared Neighborhood Hits	5
SwissProt Accessions	Q99J45, Q8BL77	Gene names	Nrbp1, Madm, Nrbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding protein (MLF1 adapter molecule) (HLS7- interacting protein kinase).

AT8B1_HUMAN
θ value	4.03905 (rank : 27)	NC score	0.004683 (rank : 36)
Query Neighborhood Hits	46	Target Neighborhood Hits	67	Shared Neighborhood Hits	2
SwissProt Accessions	O43520, Q9BTP8	Gene names	ATP8B1, ATPIC, FIC1, PFIC
Domain Architecture
Description	Probable phospholipid-transporting ATPase IC (EC 3.6.3.1) (Familial intrahepatic cholestasis type 1) (ATPase class I type 8B member 1).

DCDC2_MOUSE
θ value	4.03905 (rank : 28)	NC score	0.011831 (rank : 26)
Query Neighborhood Hits	46	Target Neighborhood Hits	247	Shared Neighborhood Hits	4
SwissProt Accessions	Q5DU00, Q5SZU0, Q80Y99	Gene names	Dcdc2, Kiaa1154
Domain Architecture	No domain graphic available
Description	Doublecortin domain-containing protein 2.

FBN3_HUMAN
θ value	4.03905 (rank : 29)	NC score	0.001551 (rank : 44)
Query Neighborhood Hits	46	Target Neighborhood Hits	543	Shared Neighborhood Hits	2
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

GEM_HUMAN
θ value	4.03905 (rank : 30)	NC score	0.007489 (rank : 29)
Query Neighborhood Hits	46	Target Neighborhood Hits	238	Shared Neighborhood Hits	4
SwissProt Accessions	P55040	Gene names	GEM, KIR
Domain Architecture
Description	GTP-binding protein GEM (GTP-binding mitogen-induced T-cell protein) (RAS-like protein KIR).

PCLO_HUMAN
θ value	4.03905 (rank : 31)	NC score	0.009206 (rank : 27)
Query Neighborhood Hits	46	Target Neighborhood Hits	2046	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

RBCC1_MOUSE
θ value	4.03905 (rank : 32)	NC score	0.005539 (rank : 35)
Query Neighborhood Hits	46	Target Neighborhood Hits	1048	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

SCN3A_HUMAN
θ value	4.03905 (rank : 33)	NC score	0.003986 (rank : 40)
Query Neighborhood Hits	46	Target Neighborhood Hits	115	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

CCD45_HUMAN
θ value	5.27518 (rank : 34)	NC score	0.007471 (rank : 30)
Query Neighborhood Hits	46	Target Neighborhood Hits	525	Shared Neighborhood Hits	5
SwissProt Accessions	Q96GE4, Q96M81	Gene names	CCDC45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

GEM_MOUSE
θ value	5.27518 (rank : 35)	NC score	0.006741 (rank : 31)
Query Neighborhood Hits	46	Target Neighborhood Hits	233	Shared Neighborhood Hits	4
SwissProt Accessions	P55041, Q8JZS1	Gene names	Gem, Kir
Domain Architecture
Description	GTP-binding protein GEM (GTP-binding mitogen-induced T-cell protein) (RAS-like protein KIR).

KLF6_MOUSE
θ value	5.27518 (rank : 36)	NC score	-0.001210 (rank : 46)
Query Neighborhood Hits	46	Target Neighborhood Hits	691	Shared Neighborhood Hits	2
SwissProt Accessions	O08584	Gene names	Klf6, Copeb, Cpbp
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 6 (Core promoter element-binding protein).

MAP1B_HUMAN
θ value	5.27518 (rank : 37)	NC score	0.012138 (rank : 25)
Query Neighborhood Hits	46	Target Neighborhood Hits	903	Shared Neighborhood Hits	10
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

RBCC1_HUMAN
θ value	5.27518 (rank : 38)	NC score	0.005797 (rank : 33)
Query Neighborhood Hits	46	Target Neighborhood Hits	1023	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

FOXO3_HUMAN
θ value	6.88961 (rank : 39)	NC score	0.004225 (rank : 38)
Query Neighborhood Hits	46	Target Neighborhood Hits	105	Shared Neighborhood Hits	2
SwissProt Accessions	O43524, O15171, Q5T2I7, Q9BZ04	Gene names	FOXO3A, FKHRL1
Domain Architecture
Description	Forkhead box protein O3A (Forkhead in rhabdomyosarcoma-like 1) (AF6q21 protein).

REPS2_HUMAN
θ value	6.88961 (rank : 40)	NC score	0.029953 (rank : 17)
Query Neighborhood Hits	46	Target Neighborhood Hits	131	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NFH8, O43428, Q8NFI5	Gene names	REPS2, POB1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

RYR3_HUMAN
θ value	6.88961 (rank : 41)	NC score	0.006059 (rank : 32)
Query Neighborhood Hits	46	Target Neighborhood Hits	134	Shared Neighborhood Hits	2
SwissProt Accessions	Q15413, O15175, Q15412	Gene names	RYR3, HBRR
Domain Architecture
Description	Ryanodine receptor 3 (Brain-type ryanodine receptor) (RyR3) (RYR-3) (Brain ryanodine receptor-calcium release channel).

CACB3_MOUSE
θ value	8.99809 (rank : 42)	NC score	0.004396 (rank : 37)
Query Neighborhood Hits	46	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	P54285	Gene names	Cacnb3, Cacnlb3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-3 (CAB3) (Calcium channel voltage-dependent subunit beta 3) (CCHB3).

NDE1_MOUSE
θ value	8.99809 (rank : 43)	NC score	0.002842 (rank : 43)
Query Neighborhood Hits	46	Target Neighborhood Hits	602	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CZA6, Q3UBS6, Q3UIC1, Q9ERR0	Gene names	Nde1, Nude
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE) (mNudE).

RB15B_MOUSE
θ value	8.99809 (rank : 44)	NC score	0.003994 (rank : 39)
Query Neighborhood Hits	46	Target Neighborhood Hits	284	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PHZ5, Q8C6G2	Gene names	Rbm15b
Domain Architecture	No domain graphic available
Description	Putative RNA-binding protein 15B (RNA-binding motif protein 15B).

SIM1_HUMAN
θ value	8.99809 (rank : 45)	NC score	0.007791 (rank : 28)
Query Neighborhood Hits	46	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	P81133, Q5TDP7	Gene names	SIM1
Domain Architecture
Description	Single-minded homolog 1.

SIRT1_HUMAN
θ value	8.99809 (rank : 46)	NC score	0.005790 (rank : 34)
Query Neighborhood Hits	46	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	Q96EB6, Q2XNF6, Q5JVQ0, Q9GZR9, Q9Y6F0	Gene names	SIRT1, SIR2L1
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-1 (EC 3.5.1.-) (hSIRT1) (hSIR2) (SIR2-like protein 1).

Hits sorted by NC score

PITM2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	46	Target Neighborhood Hits	46	Shared Neighborhood Hits	46
SwissProt Accessions	Q6ZPQ6, Q9R1P5	Gene names	Pitpnm2, Kiaa1457, Nir3
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 2 (Phosphatidylinositol transfer protein, membrane-associated 2) (Pyk2 N-terminal domain-interacting receptor 3) (NIR-3) (Drosophila retinal degeneration B homolog 2) (RdgB2).

PITM2_HUMAN
NC score	0.994327 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	46	Target Neighborhood Hits	52	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BZ72, Q9P271	Gene names	PITPNM2, KIAA1457, NIR3
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 2 (Phosphatidylinositol transfer protein, membrane-associated 2) (Pyk2 N-terminal domain-interacting receptor 3) (NIR-3).

PITM1_MOUSE
NC score	0.982944 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	46	Target Neighborhood Hits	69	Shared Neighborhood Hits	15
SwissProt Accessions	O35954	Gene names	Pitpnm1, Dres9, Mpt1, Nir2, Pitpnm
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 1 (Phosphatidylinositol transfer protein, membrane-associated 1) (PITPnm 1) (Mpt-1) (Pyk2 N-terminal domain-interacting receptor 2) (NIR-2) (Drosophila retinal degeneration B homolog 1) (RdgB1).

PITM1_HUMAN
NC score	0.972606 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	46	Target Neighborhood Hits	129	Shared Neighborhood Hits	16
SwissProt Accessions	O00562, Q6T7X3, Q8TBN3, Q9BZ73	Gene names	PITPNM1, DRES9, NIR2, PITPNM
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 1 (Phosphatidylinositol transfer protein, membrane-associated 1) (Pyk2 N-terminal domain-interacting receptor 2) (NIR-2) (Drosophila retinal degeneration B homolog).

PITM3_MOUSE
NC score	0.899737 (rank : 5)	θ value	0 (rank : 6)
Query Neighborhood Hits	46	Target Neighborhood Hits	30	Shared Neighborhood Hits	11
SwissProt Accessions	Q3UHE1, Q3UH22, Q5RIT9	Gene names	Pitpnm3, Nir1
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 3 (Phosphatidylinositol transfer protein, membrane-associated 3) (Pyk2 N-terminal domain-interacting receptor 1) (NIR-1).

PITM3_HUMAN
NC score	0.897424 (rank : 6)	θ value	0 (rank : 5)
Query Neighborhood Hits	46	Target Neighborhood Hits	30	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BZ71, Q59GH9, Q9NPQ4	Gene names	PITPNM3, NIR1
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 3 (Phosphatidylinositol transfer protein, membrane-associated 3) (Pyk2 N-terminal domain-interacting receptor 1) (NIR-1).

PIPNA_MOUSE
NC score	0.776446 (rank : 7)	θ value	8.26713e-62 (rank : 7)
Query Neighborhood Hits	46	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	P53810	Gene names	Pitpna, Pitpn
Domain Architecture
Description	Phosphatidylinositol transfer protein alpha isoform (PtdIns transfer protein alpha) (PtdInsTP) (PI-TP-alpha).

PIPNA_HUMAN
NC score	0.775340 (rank : 8)	θ value	5.35859e-61 (rank : 8)
Query Neighborhood Hits	46	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	Q00169	Gene names	PITPNA, PITPN
Domain Architecture
Description	Phosphatidylinositol transfer protein alpha isoform (PtdIns transfer protein alpha) (PtdInsTP) (PI-TP-alpha).

PIPNB_MOUSE
NC score	0.771354 (rank : 9)	θ value	6.55044e-59 (rank : 10)
Query Neighborhood Hits	46	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	P53811	Gene names	Pitpnb
Domain Architecture
Description	Phosphatidylinositol transfer protein beta isoform (PtdIns transfer protein beta) (PtdInsTP) (PI-TP-beta).

PIPNB_HUMAN
NC score	0.771167 (rank : 10)	θ value	3.84025e-59 (rank : 9)
Query Neighborhood Hits	46	Target Neighborhood Hits	15	Shared Neighborhood Hits	8
SwissProt Accessions	P48739, Q8N5W1	Gene names	PITPNB
Domain Architecture
Description	Phosphatidylinositol transfer protein beta isoform (PtdIns transfer protein beta) (PtdInsTP) (PI-TP-beta).

DDHD1_MOUSE
NC score	0.349996 (rank : 11)	θ value	1.69304e-06 (rank : 12)
Query Neighborhood Hits	46	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	Q80YA3, Q8VEF2	Gene names	Ddhd1
Domain Architecture
Description	Probable phospholipase DDHD1 (EC 3.1.1.-) (DDHD domain protein 1) (Phosphatidic acid-preferring phospholipase A1 homolog) (PA-PLA1).

DDHD1_HUMAN
NC score	0.337168 (rank : 12)	θ value	1.29631e-06 (rank : 11)
Query Neighborhood Hits	46	Target Neighborhood Hits	40	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NEL9, Q8WVH3, Q96LL2, Q9C0F8	Gene names	DDHD1, KIAA1705
Domain Architecture
Description	Probable phospholipase DDHD1 (EC 3.1.1.-) (DDHD domain protein 1) (Phosphatidic acid-preferring phospholipase A1 homolog) (PA-PLA1).

S23IP_HUMAN
NC score	0.289572 (rank : 13)	θ value	7.1131e-05 (rank : 14)
Query Neighborhood Hits	46	Target Neighborhood Hits	134	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6Y8, Q8IXH5, Q9BUK5	Gene names	SEC23IP
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein (p125).

S23IP_MOUSE
NC score	0.283790 (rank : 14)	θ value	1.09739e-05 (rank : 13)
Query Neighborhood Hits	46	Target Neighborhood Hits	363	Shared Neighborhood Hits	11
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

CYLD_HUMAN
NC score	0.058086 (rank : 15)	θ value	0.00509761 (rank : 15)
Query Neighborhood Hits	46	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NQC7, O94934, Q7L3N6, Q96EH0, Q9NZX9	Gene names	CYLD, CYLD1, KIAA0849
Domain Architecture	No domain graphic available
Description	Probable ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.1.2.15) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD) (Deubiquitinating enzyme CYLD).

CYLD_MOUSE
NC score	0.041797 (rank : 16)	θ value	1.81305 (rank : 24)
Query Neighborhood Hits	46	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q80TQ2, Q80VB3, Q8BXZ3, Q8BYL9, Q8CGB0	Gene names	Cyld, Cyld1, Kiaa0849
Domain Architecture	No domain graphic available
Description	Probable ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.1.2.15) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD) (Deubiquitinating enzyme CYLD).

REPS2_HUMAN
NC score	0.029953 (rank : 17)	θ value	6.88961 (rank : 40)
Query Neighborhood Hits	46	Target Neighborhood Hits	131	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NFH8, O43428, Q8NFI5	Gene names	REPS2, POB1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

TNF10_HUMAN
NC score	0.025893 (rank : 18)	θ value	0.62314 (rank : 18)
Query Neighborhood Hits	46	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	P50591	Gene names	TNFSF10, APO2L, TRAIL
Domain Architecture
Description	Tumor necrosis factor ligand superfamily member 10 (TNF-related apoptosis-inducing ligand) (Protein TRAIL) (Apo-2 ligand) (Apo-2L) (CD253 antigen).

LEO1_MOUSE
NC score	0.024820 (rank : 19)	θ value	0.0961366 (rank : 16)
Query Neighborhood Hits	46	Target Neighborhood Hits	946	Shared Neighborhood Hits	10
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

AIPL1_HUMAN
NC score	0.024274 (rank : 20)	θ value	0.813845 (rank : 19)
Query Neighborhood Hits	46	Target Neighborhood Hits	113	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZN9, Q9H873, Q9NS10	Gene names	AIPL1
Domain Architecture
Description	Aryl-hydrocarbon-interacting protein-like 1.

LEO1_HUMAN
NC score	0.020593 (rank : 21)	θ value	0.47712 (rank : 17)
Query Neighborhood Hits	46	Target Neighborhood Hits	958	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

NRBP_MOUSE
NC score	0.013832 (rank : 22)	θ value	1.81305 (rank : 26)
Query Neighborhood Hits	46	Target Neighborhood Hits	442	Shared Neighborhood Hits	5
SwissProt Accessions	Q99J45, Q8BL77	Gene names	Nrbp1, Madm, Nrbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding protein (MLF1 adapter molecule) (HLS7- interacting protein kinase).

NRBP_HUMAN
NC score	0.013726 (rank : 23)	θ value	1.81305 (rank : 25)
Query Neighborhood Hits	46	Target Neighborhood Hits	448	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UHY1, Q53FZ5, Q96SU3	Gene names	NRBP1, BCON3, NRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding protein.

ADDB_MOUSE
NC score	0.012470 (rank : 24)	θ value	1.06291 (rank : 21)
Query Neighborhood Hits	46	Target Neighborhood Hits	574	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

MAP1B_HUMAN
NC score	0.012138 (rank : 25)	θ value	5.27518 (rank : 37)
Query Neighborhood Hits	46	Target Neighborhood Hits	903	Shared Neighborhood Hits	10
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

DCDC2_MOUSE
NC score	0.011831 (rank : 26)	θ value	4.03905 (rank : 28)
Query Neighborhood Hits	46	Target Neighborhood Hits	247	Shared Neighborhood Hits	4
SwissProt Accessions	Q5DU00, Q5SZU0, Q80Y99	Gene names	Dcdc2, Kiaa1154
Domain Architecture	No domain graphic available
Description	Doublecortin domain-containing protein 2.

PCLO_HUMAN
NC score	0.009206 (rank : 27)	θ value	4.03905 (rank : 31)
Query Neighborhood Hits	46	Target Neighborhood Hits	2046	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SIM1_HUMAN
NC score	0.007791 (rank : 28)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	46	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	P81133, Q5TDP7	Gene names	SIM1
Domain Architecture
Description	Single-minded homolog 1.

GEM_HUMAN
NC score	0.007489 (rank : 29)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	46	Target Neighborhood Hits	238	Shared Neighborhood Hits	4
SwissProt Accessions	P55040	Gene names	GEM, KIR
Domain Architecture
Description	GTP-binding protein GEM (GTP-binding mitogen-induced T-cell protein) (RAS-like protein KIR).

CCD45_HUMAN
NC score	0.007471 (rank : 30)	θ value	5.27518 (rank : 34)
Query Neighborhood Hits	46	Target Neighborhood Hits	525	Shared Neighborhood Hits	5
SwissProt Accessions	Q96GE4, Q96M81	Gene names	CCDC45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

GEM_MOUSE
NC score	0.006741 (rank : 31)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	46	Target Neighborhood Hits	233	Shared Neighborhood Hits	4
SwissProt Accessions	P55041, Q8JZS1	Gene names	Gem, Kir
Domain Architecture
Description	GTP-binding protein GEM (GTP-binding mitogen-induced T-cell protein) (RAS-like protein KIR).

RYR3_HUMAN
NC score	0.006059 (rank : 32)	θ value	6.88961 (rank : 41)
Query Neighborhood Hits	46	Target Neighborhood Hits	134	Shared Neighborhood Hits	2
SwissProt Accessions	Q15413, O15175, Q15412	Gene names	RYR3, HBRR
Domain Architecture
Description	Ryanodine receptor 3 (Brain-type ryanodine receptor) (RyR3) (RYR-3) (Brain ryanodine receptor-calcium release channel).

RBCC1_HUMAN
NC score	0.005797 (rank : 33)	θ value	5.27518 (rank : 38)
Query Neighborhood Hits	46	Target Neighborhood Hits	1023	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

SIRT1_HUMAN
NC score	0.005790 (rank : 34)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	46	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	Q96EB6, Q2XNF6, Q5JVQ0, Q9GZR9, Q9Y6F0	Gene names	SIRT1, SIR2L1
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-1 (EC 3.5.1.-) (hSIRT1) (hSIR2) (SIR2-like protein 1).

RBCC1_MOUSE
NC score	0.005539 (rank : 35)	θ value	4.03905 (rank : 32)
Query Neighborhood Hits	46	Target Neighborhood Hits	1048	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

AT8B1_HUMAN
NC score	0.004683 (rank : 36)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	46	Target Neighborhood Hits	67	Shared Neighborhood Hits	2
SwissProt Accessions	O43520, Q9BTP8	Gene names	ATP8B1, ATPIC, FIC1, PFIC
Domain Architecture
Description	Probable phospholipid-transporting ATPase IC (EC 3.6.3.1) (Familial intrahepatic cholestasis type 1) (ATPase class I type 8B member 1).

CACB3_MOUSE
NC score	0.004396 (rank : 37)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	46	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	P54285	Gene names	Cacnb3, Cacnlb3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-3 (CAB3) (Calcium channel voltage-dependent subunit beta 3) (CCHB3).

FOXO3_HUMAN
NC score	0.004225 (rank : 38)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	46	Target Neighborhood Hits	105	Shared Neighborhood Hits	2
SwissProt Accessions	O43524, O15171, Q5T2I7, Q9BZ04	Gene names	FOXO3A, FKHRL1
Domain Architecture
Description	Forkhead box protein O3A (Forkhead in rhabdomyosarcoma-like 1) (AF6q21 protein).

RB15B_MOUSE
NC score	0.003994 (rank : 39)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	46	Target Neighborhood Hits	284	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PHZ5, Q8C6G2	Gene names	Rbm15b
Domain Architecture	No domain graphic available
Description	Putative RNA-binding protein 15B (RNA-binding motif protein 15B).

SCN3A_HUMAN
NC score	0.003986 (rank : 40)	θ value	4.03905 (rank : 33)
Query Neighborhood Hits	46	Target Neighborhood Hits	115	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

SUHW4_HUMAN
NC score	0.003805 (rank : 41)	θ value	1.38821 (rank : 23)
Query Neighborhood Hits	46	Target Neighborhood Hits	860	Shared Neighborhood Hits	6
SwissProt Accessions	Q6N043, Q6MZM6, Q6N085, Q9H0U5, Q9HCI8, Q9NXS0	Gene names	SUHW4, KIAA1584
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

RIPK1_MOUSE
NC score	0.003155 (rank : 42)	θ value	1.38821 (rank : 22)
Query Neighborhood Hits	46	Target Neighborhood Hits	874	Shared Neighborhood Hits	4
SwissProt Accessions	Q60855, Q3U0J3, Q8CD90	Gene names	Ripk1, Rinp, Rip
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

NDE1_MOUSE
NC score	0.002842 (rank : 43)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	46	Target Neighborhood Hits	602	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CZA6, Q3UBS6, Q3UIC1, Q9ERR0	Gene names	Nde1, Nude
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE) (mNudE).

FBN3_HUMAN
NC score	0.001551 (rank : 44)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	46	Target Neighborhood Hits	543	Shared Neighborhood Hits	2
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

STK10_MOUSE
NC score	0.000321 (rank : 45)	θ value	0.813845 (rank : 20)
Query Neighborhood Hits	46	Target Neighborhood Hits	2132	Shared Neighborhood Hits	12
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

KLF6_MOUSE
NC score	-0.001210 (rank : 46)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	46	Target Neighborhood Hits	691	Shared Neighborhood Hits	2
SwissProt Accessions	O08584	Gene names	Klf6, Copeb, Cpbp
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 6 (Core promoter element-binding protein).