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Network neighborhood for query Sequence : REPS2_HUMAN

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REPS2_HUMAN
SwissProt Accessions	Q8NFH8, O43428, Q8NFI5	Gene names	REPS2, POB1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

REPS2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	131	Target Neighborhood Hits	131	Shared Neighborhood Hits	131
SwissProt Accessions	Q8NFH8, O43428, Q8NFI5	Gene names	REPS2, POB1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

REPS2_MOUSE
θ value	0 (rank : 2)	NC score	0.967026 (rank : 2)
Query Neighborhood Hits	131	Target Neighborhood Hits	102	Shared Neighborhood Hits	56
SwissProt Accessions	Q80XA6	Gene names	Reps2, Pob1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

REPS1_MOUSE
θ value	8.24801e-70 (rank : 3)	NC score	0.836309 (rank : 3)
Query Neighborhood Hits	131	Target Neighborhood Hits	204	Shared Neighborhood Hits	31
SwissProt Accessions	O54916, Q8C9J9, Q99LR8	Gene names	Reps1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

REPS1_HUMAN
θ value	5.37103e-53 (rank : 4)	NC score	0.828145 (rank : 4)
Query Neighborhood Hits	131	Target Neighborhood Hits	205	Shared Neighborhood Hits	36
SwissProt Accessions	Q96D71, Q8NDR7, Q8WU62, Q9BXY9	Gene names	REPS1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

ITSN2_HUMAN
θ value	5.8054e-15 (rank : 5)	NC score	0.299297 (rank : 16)
Query Neighborhood Hits	131	Target Neighborhood Hits	1173	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

ITSN2_MOUSE
θ value	4.91457e-14 (rank : 6)	NC score	0.288696 (rank : 17)
Query Neighborhood Hits	131	Target Neighborhood Hits	1371	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

ITSN1_MOUSE
θ value	8.38298e-14 (rank : 7)	NC score	0.285919 (rank : 18)
Query Neighborhood Hits	131	Target Neighborhood Hits	1669	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

ITSN1_HUMAN
θ value	2.43908e-13 (rank : 8)	NC score	0.284012 (rank : 19)
Query Neighborhood Hits	131	Target Neighborhood Hits	1757	Shared Neighborhood Hits	62
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

EHD4_HUMAN
θ value	3.89403e-11 (rank : 9)	NC score	0.516525 (rank : 6)
Query Neighborhood Hits	131	Target Neighborhood Hits	41	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H223, Q9HAR1, Q9NZN2	Gene names	EHD4, HCA10, HCA11
Domain Architecture
Description	EH-domain-containing protein 4 (Hepatocellular carcinoma-associated protein 10/11).

EHD4_MOUSE
θ value	3.89403e-11 (rank : 10)	NC score	0.520896 (rank : 5)
Query Neighborhood Hits	131	Target Neighborhood Hits	40	Shared Neighborhood Hits	21
SwissProt Accessions	Q9EQP2	Gene names	Ehd4, Past2
Domain Architecture
Description	EH-domain-containing protein 4 (mPAST2).

EP15_MOUSE
θ value	1.133e-10 (rank : 11)	NC score	0.389606 (rank : 12)
Query Neighborhood Hits	131	Target Neighborhood Hits	820	Shared Neighborhood Hits	42
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

EP15_HUMAN
θ value	1.47974e-10 (rank : 12)	NC score	0.373013 (rank : 13)
Query Neighborhood Hits	131	Target Neighborhood Hits	1021	Shared Neighborhood Hits	45
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

EP15R_HUMAN
θ value	3.29651e-10 (rank : 13)	NC score	0.331262 (rank : 15)
Query Neighborhood Hits	131	Target Neighborhood Hits	1083	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

EP15R_MOUSE
θ value	1.25267e-09 (rank : 14)	NC score	0.336604 (rank : 14)
Query Neighborhood Hits	131	Target Neighborhood Hits	1135	Shared Neighborhood Hits	53
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

EHD2_HUMAN
θ value	3.64472e-09 (rank : 15)	NC score	0.515413 (rank : 7)
Query Neighborhood Hits	131	Target Neighborhood Hits	29	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NZN4, Q96CB6	Gene names	EHD2
Domain Architecture
Description	EH-domain-containing protein 2.

EHD1_HUMAN
θ value	4.0297e-08 (rank : 16)	NC score	0.506406 (rank : 8)
Query Neighborhood Hits	131	Target Neighborhood Hits	36	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H4M9, O14611, Q9UNR3	Gene names	EHD1, PAST, PAST1
Domain Architecture
Description	EH-domain-containing protein 1 (Testilin) (hPAST1).

EHD1_MOUSE
θ value	5.26297e-08 (rank : 17)	NC score	0.505824 (rank : 9)
Query Neighborhood Hits	131	Target Neighborhood Hits	37	Shared Neighborhood Hits	21
SwissProt Accessions	Q9WVK4	Gene names	Ehd1, Past1
Domain Architecture
Description	EH-domain-containing protein 1 (mPAST1).

EHD3_MOUSE
θ value	1.17247e-07 (rank : 18)	NC score	0.501629 (rank : 10)
Query Neighborhood Hits	131	Target Neighborhood Hits	34	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QXY6	Gene names	Ehd3, Ehd2
Domain Architecture
Description	EH-domain-containing protein 3.

EHD3_HUMAN
θ value	5.81887e-07 (rank : 19)	NC score	0.498063 (rank : 11)
Query Neighborhood Hits	131	Target Neighborhood Hits	33	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NZN3, Q8N514, Q9NZB3	Gene names	EHD3, EHD2
Domain Architecture
Description	EH-domain-containing protein 3.

RGS3_MOUSE
θ value	0.00102713 (rank : 20)	NC score	0.058900 (rank : 98)
Query Neighborhood Hits	131	Target Neighborhood Hits	1621	Shared Neighborhood Hits	59
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

IWS1_HUMAN
θ value	0.0431538 (rank : 21)	NC score	0.050888 (rank : 183)
Query Neighborhood Hits	131	Target Neighborhood Hits	1241	Shared Neighborhood Hits	41
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

BLNK_MOUSE
θ value	0.0563607 (rank : 22)	NC score	0.080993 (rank : 33)
Query Neighborhood Hits	131	Target Neighborhood Hits	296	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

SELPL_MOUSE
θ value	0.0563607 (rank : 23)	NC score	0.072679 (rank : 49)
Query Neighborhood Hits	131	Target Neighborhood Hits	588	Shared Neighborhood Hits	41
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

ZN750_HUMAN
θ value	0.0736092 (rank : 24)	NC score	0.055856 (rank : 124)
Query Neighborhood Hits	131	Target Neighborhood Hits	183	Shared Neighborhood Hits	10
SwissProt Accessions	Q32MQ0, Q9H899	Gene names	ZNF750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

LATS1_HUMAN
θ value	0.0961366 (rank : 25)	NC score	0.014574 (rank : 264)
Query Neighborhood Hits	131	Target Neighborhood Hits	1057	Shared Neighborhood Hits	30
SwissProt Accessions	O95835, Q6PKD0	Gene names	LATS1, WARTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts).

PITM2_HUMAN
θ value	0.0961366 (rank : 26)	NC score	0.053326 (rank : 145)
Query Neighborhood Hits	131	Target Neighborhood Hits	52	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BZ72, Q9P271	Gene names	PITPNM2, KIAA1457, NIR3
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 2 (Phosphatidylinositol transfer protein, membrane-associated 2) (Pyk2 N-terminal domain-interacting receptor 3) (NIR-3).

ICB1_MOUSE
θ value	0.163984 (rank : 27)	NC score	0.043263 (rank : 214)
Query Neighborhood Hits	131	Target Neighborhood Hits	69	Shared Neighborhood Hits	7
SwissProt Accessions	Q91YX0	Gene names	Icb1
Domain Architecture	No domain graphic available
Description	Induced by contact to basement membrane 1 protein homolog (ICB-1 protein).

NRIP1_MOUSE
θ value	0.163984 (rank : 28)	NC score	0.045313 (rank : 211)
Query Neighborhood Hits	131	Target Neighborhood Hits	110	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CBD1, Q8C3Y8, Q9Z2K2	Gene names	Nrip1
Domain Architecture	No domain graphic available
Description	Nuclear receptor-interacting protein 1 (Nuclear factor RIP140) (Receptor-interacting protein 140).

ATX7_MOUSE
θ value	0.21417 (rank : 29)	NC score	0.060346 (rank : 89)
Query Neighborhood Hits	131	Target Neighborhood Hits	328	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

RPGR1_MOUSE
θ value	0.21417 (rank : 30)	NC score	0.059767 (rank : 92)
Query Neighborhood Hits	131	Target Neighborhood Hits	713	Shared Neighborhood Hits	26
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

SEPT9_HUMAN
θ value	0.21417 (rank : 31)	NC score	0.047256 (rank : 207)
Query Neighborhood Hits	131	Target Neighborhood Hits	706	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

TARSH_HUMAN
θ value	0.21417 (rank : 32)	NC score	0.057022 (rank : 112)
Query Neighborhood Hits	131	Target Neighborhood Hits	768	Shared Neighborhood Hits	39
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

GOGA2_HUMAN
θ value	0.279714 (rank : 33)	NC score	0.074945 (rank : 44)
Query Neighborhood Hits	131	Target Neighborhood Hits	856	Shared Neighborhood Hits	33
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

GOGA2_MOUSE
θ value	0.279714 (rank : 34)	NC score	0.083987 (rank : 26)
Query Neighborhood Hits	131	Target Neighborhood Hits	944	Shared Neighborhood Hits	36
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

PI5PA_HUMAN
θ value	0.279714 (rank : 35)	NC score	0.041299 (rank : 220)
Query Neighborhood Hits	131	Target Neighborhood Hits	749	Shared Neighborhood Hits	35
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

TGON2_HUMAN
θ value	0.279714 (rank : 36)	NC score	0.046674 (rank : 208)
Query Neighborhood Hits	131	Target Neighborhood Hits	1037	Shared Neighborhood Hits	40
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

ASPP1_MOUSE
θ value	0.365318 (rank : 37)	NC score	0.058019 (rank : 102)
Query Neighborhood Hits	131	Target Neighborhood Hits	1244	Shared Neighborhood Hits	53
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ARI5B_HUMAN
θ value	0.47712 (rank : 38)	NC score	0.039491 (rank : 224)
Query Neighborhood Hits	131	Target Neighborhood Hits	328	Shared Neighborhood Hits	23
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

K2027_HUMAN
θ value	0.47712 (rank : 39)	NC score	0.047920 (rank : 206)
Query Neighborhood Hits	131	Target Neighborhood Hits	194	Shared Neighborhood Hits	18
SwissProt Accessions	Q6ZVF9, Q8IVE4	Gene names	KIAA2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

JHD3C_MOUSE
θ value	0.62314 (rank : 40)	NC score	0.019198 (rank : 255)
Query Neighborhood Hits	131	Target Neighborhood Hits	84	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VCD7, Q3UNP7, Q69ZZ5, Q8BUY6, Q8BWA1	Gene names	Jmjd2c, Jhdm3c, Kiaa0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C).

KIFC3_HUMAN
θ value	0.62314 (rank : 41)	NC score	0.043324 (rank : 213)
Query Neighborhood Hits	131	Target Neighborhood Hits	619	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BVG8, O75299, Q8IUT3, Q96HW6	Gene names	KIFC3
Domain Architecture
Description	Kinesin-like protein KIFC3.

NFH_MOUSE
θ value	0.62314 (rank : 42)	NC score	0.035984 (rank : 229)
Query Neighborhood Hits	131	Target Neighborhood Hits	2247	Shared Neighborhood Hits	75
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SRRM1_MOUSE
θ value	0.62314 (rank : 43)	NC score	0.063661 (rank : 78)
Query Neighborhood Hits	131	Target Neighborhood Hits	966	Shared Neighborhood Hits	54
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TTF1_MOUSE
θ value	0.62314 (rank : 44)	NC score	0.042831 (rank : 215)
Query Neighborhood Hits	131	Target Neighborhood Hits	277	Shared Neighborhood Hits	16
SwissProt Accessions	Q62187, Q9JKK5	Gene names	Ttf1
Domain Architecture	No domain graphic available
Description	Transcription termination factor 1 (TTF-1) (TTF-I) (mTFF-I) (RNA polymerase I termination factor).

ICK_HUMAN
θ value	0.813845 (rank : 45)	NC score	0.007653 (rank : 277)
Query Neighborhood Hits	131	Target Neighborhood Hits	867	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UPZ9, O75985, Q5THL2, Q8IYH8, Q9BX17, Q9NYX3	Gene names	ICK, KIAA0936
Domain Architecture
Description	Serine/threonine-protein kinase ICK (EC 2.7.11.22) (Intestinal cell kinase) (hICK) (MAK-related kinase) (MRK) (Laryngeal cancer kinase 2) (LCK2).

MAP9_HUMAN
θ value	0.813845 (rank : 46)	NC score	0.042595 (rank : 216)
Query Neighborhood Hits	131	Target Neighborhood Hits	518	Shared Neighborhood Hits	18
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

NCOA6_MOUSE
θ value	0.813845 (rank : 47)	NC score	0.055892 (rank : 120)
Query Neighborhood Hits	131	Target Neighborhood Hits	1076	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

RUNX1_HUMAN
θ value	0.813845 (rank : 48)	NC score	0.033186 (rank : 232)
Query Neighborhood Hits	131	Target Neighborhood Hits	94	Shared Neighborhood Hits	8
SwissProt Accessions	Q01196, O60472, O60473, O76047, O76089, Q13081, Q13755, Q13756, Q13757, Q13758, Q13759, Q15341, Q15343, Q16122, Q16284, Q16285, Q16286, Q16346, Q16347, Q92479	Gene names	RUNX1, AML1, CBFA2
Domain Architecture
Description	Runt-related transcription factor 1 (Core-binding factor, alpha 2 subunit) (CBF-alpha 2) (Acute myeloid leukemia 1 protein) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEBP2-alpha B) (PEA2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit).

SFRIP_HUMAN
θ value	0.813845 (rank : 49)	NC score	0.062611 (rank : 83)
Query Neighborhood Hits	131	Target Neighborhood Hits	530	Shared Neighborhood Hits	32
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

TRIPB_HUMAN
θ value	0.813845 (rank : 50)	NC score	0.054485 (rank : 134)
Query Neighborhood Hits	131	Target Neighborhood Hits	1587	Shared Neighborhood Hits	41
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

ABL1_HUMAN
θ value	1.06291 (rank : 51)	NC score	0.011941 (rank : 270)
Query Neighborhood Hits	131	Target Neighborhood Hits	1220	Shared Neighborhood Hits	31
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

BSN_HUMAN
θ value	1.06291 (rank : 52)	NC score	0.064462 (rank : 76)
Query Neighborhood Hits	131	Target Neighborhood Hits	1537	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

MLL3_HUMAN
θ value	1.06291 (rank : 53)	NC score	0.059504 (rank : 95)
Query Neighborhood Hits	131	Target Neighborhood Hits	1644	Shared Neighborhood Hits	58
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MYPN_MOUSE
θ value	1.06291 (rank : 54)	NC score	0.013861 (rank : 267)
Query Neighborhood Hits	131	Target Neighborhood Hits	421	Shared Neighborhood Hits	13
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

PCLO_HUMAN
θ value	1.06291 (rank : 55)	NC score	0.074531 (rank : 46)
Query Neighborhood Hits	131	Target Neighborhood Hits	2046	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SPY2_MOUSE
θ value	1.06291 (rank : 56)	NC score	0.029428 (rank : 239)
Query Neighborhood Hits	131	Target Neighborhood Hits	71	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QXV8, Q9WUQ9	Gene names	Spry2
Domain Architecture
Description	Sprouty homolog 2 (Spry-2).

SYNG_HUMAN
θ value	1.06291 (rank : 57)	NC score	0.120107 (rank : 23)
Query Neighborhood Hits	131	Target Neighborhood Hits	160	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UMZ2, Q6ZT17	Gene names	AP1GBP1, SYNG
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

SYNG_MOUSE
θ value	1.06291 (rank : 58)	NC score	0.135717 (rank : 22)
Query Neighborhood Hits	131	Target Neighborhood Hits	206	Shared Neighborhood Hits	27
SwissProt Accessions	Q5SV85, Q5SV84, Q6PHT6	Gene names	Ap1gbp1, Syng
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

TP53B_HUMAN
θ value	1.06291 (rank : 59)	NC score	0.057374 (rank : 108)
Query Neighborhood Hits	131	Target Neighborhood Hits	413	Shared Neighborhood Hits	26
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

ATX7_HUMAN
θ value	1.38821 (rank : 60)	NC score	0.061578 (rank : 84)
Query Neighborhood Hits	131	Target Neighborhood Hits	351	Shared Neighborhood Hits	24
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

CSPG3_HUMAN
θ value	1.38821 (rank : 61)	NC score	0.016650 (rank : 262)
Query Neighborhood Hits	131	Target Neighborhood Hits	676	Shared Neighborhood Hits	17
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

SKI_MOUSE
θ value	1.38821 (rank : 62)	NC score	0.052945 (rank : 150)
Query Neighborhood Hits	131	Target Neighborhood Hits	423	Shared Neighborhood Hits	23
SwissProt Accessions	Q60698, Q8VIL5	Gene names	Ski
Domain Architecture	No domain graphic available
Description	Ski oncogene (C-ski).

SRRM2_MOUSE
θ value	1.38821 (rank : 63)	NC score	0.050280 (rank : 195)
Query Neighborhood Hits	131	Target Neighborhood Hits	1470	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

CQ028_HUMAN
θ value	1.81305 (rank : 64)	NC score	0.026028 (rank : 246)
Query Neighborhood Hits	131	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IV36, Q8N5L6, Q8TE83, Q9NT34	Gene names	C17orf28, DMC1
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf28 (Down-regulated in multiple cancers- 1).

MAP4_HUMAN
θ value	1.81305 (rank : 65)	NC score	0.035490 (rank : 230)
Query Neighborhood Hits	131	Target Neighborhood Hits	428	Shared Neighborhood Hits	25
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

RS6_HUMAN
θ value	1.81305 (rank : 66)	NC score	0.061404 (rank : 85)
Query Neighborhood Hits	131	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	P62753, P08227, P10660, Q4VBY7, Q8N6Z7	Gene names	RPS6
Domain Architecture	No domain graphic available
Description	40S ribosomal protein S6 (Phosphoprotein NP33).

RS6_MOUSE
θ value	1.81305 (rank : 67)	NC score	0.061404 (rank : 86)
Query Neighborhood Hits	131	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	P62754, P08227, P10660	Gene names	Rps6
Domain Architecture	No domain graphic available
Description	40S ribosomal protein S6 (Phosphoprotein NP33).

WBS14_HUMAN
θ value	1.81305 (rank : 68)	NC score	0.040452 (rank : 222)
Query Neighborhood Hits	131	Target Neighborhood Hits	273	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

ASXL1_MOUSE
θ value	2.36792 (rank : 69)	NC score	0.041311 (rank : 219)
Query Neighborhood Hits	131	Target Neighborhood Hits	182	Shared Neighborhood Hits	18
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

CS016_HUMAN
θ value	2.36792 (rank : 70)	NC score	0.066215 (rank : 66)
Query Neighborhood Hits	131	Target Neighborhood Hits	310	Shared Neighborhood Hits	36
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

CUTL1_MOUSE
θ value	2.36792 (rank : 71)	NC score	0.055664 (rank : 126)
Query Neighborhood Hits	131	Target Neighborhood Hits	1620	Shared Neighborhood Hits	61
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

ERRFI_MOUSE
θ value	2.36792 (rank : 72)	NC score	0.037028 (rank : 228)
Query Neighborhood Hits	131	Target Neighborhood Hits	72	Shared Neighborhood Hits	8
SwissProt Accessions	Q99JZ7	Gene names	Errfi1, Mig6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein homolog) (Mig-6).

FA5_HUMAN
θ value	2.36792 (rank : 73)	NC score	0.019087 (rank : 256)
Query Neighborhood Hits	131	Target Neighborhood Hits	172	Shared Neighborhood Hits	12
SwissProt Accessions	P12259, Q14285, Q6UPU6	Gene names	F5
Domain Architecture
Description	Coagulation factor V precursor (Activated protein C cofactor) [Contains: Coagulation factor V heavy chain; Coagulation factor V light chain].

K1543_MOUSE
θ value	2.36792 (rank : 74)	NC score	0.050218 (rank : 196)
Query Neighborhood Hits	131	Target Neighborhood Hits	497	Shared Neighborhood Hits	31
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

KIFC3_MOUSE
θ value	2.36792 (rank : 75)	NC score	0.041814 (rank : 217)
Query Neighborhood Hits	131	Target Neighborhood Hits	571	Shared Neighborhood Hits	25
SwissProt Accessions	O35231, Q91YQ2	Gene names	Kifc3
Domain Architecture
Description	Kinesin-like protein KIFC3.

LPXN_MOUSE
θ value	2.36792 (rank : 76)	NC score	0.010107 (rank : 272)
Query Neighborhood Hits	131	Target Neighborhood Hits	227	Shared Neighborhood Hits	8
SwissProt Accessions	Q99N69	Gene names	Lpxn
Domain Architecture	No domain graphic available
Description	Leupaxin.

MACF1_HUMAN
θ value	2.36792 (rank : 77)	NC score	0.038256 (rank : 227)
Query Neighborhood Hits	131	Target Neighborhood Hits	1341	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

PO121_HUMAN
θ value	2.36792 (rank : 78)	NC score	0.041778 (rank : 218)
Query Neighborhood Hits	131	Target Neighborhood Hits	344	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

RBBP6_HUMAN
θ value	2.36792 (rank : 79)	NC score	0.040260 (rank : 223)
Query Neighborhood Hits	131	Target Neighborhood Hits	1135	Shared Neighborhood Hits	45
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

STAR8_HUMAN
θ value	2.36792 (rank : 80)	NC score	0.015712 (rank : 263)
Query Neighborhood Hits	131	Target Neighborhood Hits	216	Shared Neighborhood Hits	14
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

ABL1_MOUSE
θ value	3.0926 (rank : 81)	NC score	0.014123 (rank : 266)
Query Neighborhood Hits	131	Target Neighborhood Hits	1178	Shared Neighborhood Hits	38
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

BPA1_MOUSE
θ value	3.0926 (rank : 82)	NC score	0.040942 (rank : 221)
Query Neighborhood Hits	131	Target Neighborhood Hits	1477	Shared Neighborhood Hits	35
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

M4K4_MOUSE
θ value	3.0926 (rank : 83)	NC score	0.017366 (rank : 259)
Query Neighborhood Hits	131	Target Neighborhood Hits	1560	Shared Neighborhood Hits	38
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MACF4_HUMAN
θ value	3.0926 (rank : 84)	NC score	0.046108 (rank : 209)
Query Neighborhood Hits	131	Target Neighborhood Hits	1321	Shared Neighborhood Hits	42
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

NCOA6_HUMAN
θ value	3.0926 (rank : 85)	NC score	0.051685 (rank : 170)
Query Neighborhood Hits	131	Target Neighborhood Hits	1202	Shared Neighborhood Hits	48
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NSD1_HUMAN
θ value	3.0926 (rank : 86)	NC score	0.022197 (rank : 250)
Query Neighborhood Hits	131	Target Neighborhood Hits	427	Shared Neighborhood Hits	26
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

PWWP2_HUMAN
θ value	3.0926 (rank : 87)	NC score	0.033994 (rank : 231)
Query Neighborhood Hits	131	Target Neighborhood Hits	80	Shared Neighborhood Hits	7
SwissProt Accessions	Q6NUJ5, Q5SZI0, Q6ZQX5, Q96F43	Gene names	PWWP2
Domain Architecture	No domain graphic available
Description	PWWP domain-containing protein 2.

ROCK2_MOUSE
θ value	3.0926 (rank : 88)	NC score	0.032367 (rank : 234)
Query Neighborhood Hits	131	Target Neighborhood Hits	2072	Shared Neighborhood Hits	47
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

TRAK1_HUMAN
θ value	3.0926 (rank : 89)	NC score	0.063468 (rank : 79)
Query Neighborhood Hits	131	Target Neighborhood Hits	660	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UPV9, Q96B69	Gene names	TRAK1, KIAA1042, OIP106
Domain Architecture	No domain graphic available
Description	Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase- interacting protein).

AFF2_MOUSE
θ value	4.03905 (rank : 90)	NC score	0.028777 (rank : 240)
Query Neighborhood Hits	131	Target Neighborhood Hits	225	Shared Neighborhood Hits	24
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

CCD25_HUMAN
θ value	4.03905 (rank : 91)	NC score	0.032782 (rank : 233)
Query Neighborhood Hits	131	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	Q86WR0, Q96SI2, Q9NV98	Gene names	CCDC25
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 25.

CCD25_MOUSE
θ value	4.03905 (rank : 92)	NC score	0.031911 (rank : 235)
Query Neighborhood Hits	131	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q78PG9, Q9CSQ8, Q9CUF8	Gene names	Ccdc25
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 25.

EFS_MOUSE
θ value	4.03905 (rank : 93)	NC score	0.062761 (rank : 82)
Query Neighborhood Hits	131	Target Neighborhood Hits	389	Shared Neighborhood Hits	25
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

ENKUR_HUMAN
θ value	4.03905 (rank : 94)	NC score	0.028323 (rank : 242)
Query Neighborhood Hits	131	Target Neighborhood Hits	64	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TC29	Gene names	C10orf63
Domain Architecture	No domain graphic available
Description	Enkurin.

HEM1_HUMAN
θ value	4.03905 (rank : 95)	NC score	0.012221 (rank : 269)
Query Neighborhood Hits	131	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	P13196	Gene names	ALAS1, ALASH
Domain Architecture
Description	5-aminolevulinate synthase, nonspecific, mitochondrial precursor (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta-aminolevulinate synthase) (Delta-ALA synthetase) (ALAS-H).

K1802_MOUSE
θ value	4.03905 (rank : 96)	NC score	0.026061 (rank : 245)
Query Neighborhood Hits	131	Target Neighborhood Hits	1596	Shared Neighborhood Hits	48
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MA1B1_HUMAN
θ value	4.03905 (rank : 97)	NC score	0.024681 (rank : 248)
Query Neighborhood Hits	131	Target Neighborhood Hits	125	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UKM7, Q5VSG3, Q9BRS9, Q9Y5K7	Gene names	MAN1B1
Domain Architecture
Description	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (Mannosidase alpha class 1B member 1) (Man9GlcNAc2-specific-processing alpha-mannosidase).

MAST4_HUMAN
θ value	4.03905 (rank : 98)	NC score	0.008929 (rank : 275)
Query Neighborhood Hits	131	Target Neighborhood Hits	1804	Shared Neighborhood Hits	42
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

RC3H1_HUMAN
θ value	4.03905 (rank : 99)	NC score	0.014494 (rank : 265)
Query Neighborhood Hits	131	Target Neighborhood Hits	433	Shared Neighborhood Hits	14
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

RFX1_MOUSE
θ value	4.03905 (rank : 100)	NC score	0.020324 (rank : 254)
Query Neighborhood Hits	131	Target Neighborhood Hits	181	Shared Neighborhood Hits	25
SwissProt Accessions	P48377	Gene names	Rfx1
Domain Architecture
Description	DNA-binding protein RFX1.

SPY2_HUMAN
θ value	4.03905 (rank : 101)	NC score	0.023029 (rank : 249)
Query Neighborhood Hits	131	Target Neighborhood Hits	66	Shared Neighborhood Hits	3
SwissProt Accessions	O43597, Q5T6Z7	Gene names	SPRY2
Domain Architecture
Description	Sprouty homolog 2 (Spry-2).

TIP60_MOUSE
θ value	4.03905 (rank : 102)	NC score	0.018133 (rank : 258)
Query Neighborhood Hits	131	Target Neighborhood Hits	95	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CHK4, Q8CGZ3, Q8CGZ4, Q8VIH0	Gene names	Htatip, Tip60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60).

CABYR_HUMAN
θ value	5.27518 (rank : 103)	NC score	0.021246 (rank : 253)
Query Neighborhood Hits	131	Target Neighborhood Hits	87	Shared Neighborhood Hits	11
SwissProt Accessions	O75952, Q8WXW5, Q9HAY3, Q9HAY4, Q9HAY5, Q9HCY9	Gene names	CABYR, CBP86, FSP2
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86) (Fibrousheathin-2) (FSP-2).

CI039_HUMAN
θ value	5.27518 (rank : 104)	NC score	0.049578 (rank : 205)
Query Neighborhood Hits	131	Target Neighborhood Hits	1171	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

DDEF1_MOUSE
θ value	5.27518 (rank : 105)	NC score	0.045597 (rank : 210)
Query Neighborhood Hits	131	Target Neighborhood Hits	592	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

NACAM_MOUSE
θ value	5.27518 (rank : 106)	NC score	0.053027 (rank : 148)
Query Neighborhood Hits	131	Target Neighborhood Hits	1866	Shared Neighborhood Hits	74
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PCLO_MOUSE
θ value	5.27518 (rank : 107)	NC score	0.061261 (rank : 88)
Query Neighborhood Hits	131	Target Neighborhood Hits	2275	Shared Neighborhood Hits	76
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PDLI7_HUMAN
θ value	5.27518 (rank : 108)	NC score	0.009415 (rank : 274)
Query Neighborhood Hits	131	Target Neighborhood Hits	547	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PITM3_MOUSE
θ value	5.27518 (rank : 109)	NC score	0.031886 (rank : 236)
Query Neighborhood Hits	131	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	Q3UHE1, Q3UH22, Q5RIT9	Gene names	Pitpnm3, Nir1
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 3 (Phosphatidylinositol transfer protein, membrane-associated 3) (Pyk2 N-terminal domain-interacting receptor 1) (NIR-1).

PRGC2_HUMAN
θ value	5.27518 (rank : 110)	NC score	0.025523 (rank : 247)
Query Neighborhood Hits	131	Target Neighborhood Hits	272	Shared Neighborhood Hits	21
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

RENT2_HUMAN
θ value	5.27518 (rank : 111)	NC score	0.054805 (rank : 133)
Query Neighborhood Hits	131	Target Neighborhood Hits	618	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

SKI_HUMAN
θ value	5.27518 (rank : 112)	NC score	0.057132 (rank : 110)
Query Neighborhood Hits	131	Target Neighborhood Hits	423	Shared Neighborhood Hits	25
SwissProt Accessions	P12755, Q5SYT7	Gene names	SKI
Domain Architecture
Description	Ski oncogene (C-ski).

2A5D_HUMAN
θ value	6.88961 (rank : 113)	NC score	0.009461 (rank : 273)
Query Neighborhood Hits	131	Target Neighborhood Hits	59	Shared Neighborhood Hits	6
SwissProt Accessions	Q14738, O00494, O00696, Q15171	Gene names	PPP2R5D
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PP2A, B subunit, B' delta isoform) (PP2A, B subunit, B56 delta isoform) (PP2A, B subunit, PR61 delta isoform) (PP2A, B subunit, R5 delta isoform).

BLNK_HUMAN
θ value	6.88961 (rank : 114)	NC score	0.039357 (rank : 226)
Query Neighborhood Hits	131	Target Neighborhood Hits	228	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WV28, O75498, O75499	Gene names	BLNK, BASH, SLP65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (SLP-65).

NCOR1_HUMAN
θ value	6.88961 (rank : 115)	NC score	0.028416 (rank : 241)
Query Neighborhood Hits	131	Target Neighborhood Hits	577	Shared Neighborhood Hits	36
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

NFAC3_HUMAN
θ value	6.88961 (rank : 116)	NC score	0.008108 (rank : 276)
Query Neighborhood Hits	131	Target Neighborhood Hits	102	Shared Neighborhood Hits	4
SwissProt Accessions	Q12968, O75211, Q14516, Q99840, Q99841, Q99842	Gene names	NFATC3, NFAT4
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx).

PITM2_MOUSE
θ value	6.88961 (rank : 117)	NC score	0.029953 (rank : 237)
Query Neighborhood Hits	131	Target Neighborhood Hits	46	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZPQ6, Q9R1P5	Gene names	Pitpnm2, Kiaa1457, Nir3
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 2 (Phosphatidylinositol transfer protein, membrane-associated 2) (Pyk2 N-terminal domain-interacting receptor 3) (NIR-3) (Drosophila retinal degeneration B homolog 2) (RdgB2).

RAPH1_HUMAN
θ value	6.88961 (rank : 118)	NC score	0.044178 (rank : 212)
Query Neighborhood Hits	131	Target Neighborhood Hits	593	Shared Neighborhood Hits	43
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

ROCK2_HUMAN
θ value	6.88961 (rank : 119)	NC score	0.027861 (rank : 243)
Query Neighborhood Hits	131	Target Neighborhood Hits	2073	Shared Neighborhood Hits	45
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

RPGR1_HUMAN
θ value	6.88961 (rank : 120)	NC score	0.059640 (rank : 93)
Query Neighborhood Hits	131	Target Neighborhood Hits	578	Shared Neighborhood Hits	31
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

SAPS1_HUMAN
θ value	6.88961 (rank : 121)	NC score	0.026072 (rank : 244)
Query Neighborhood Hits	131	Target Neighborhood Hits	704	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SEPT9_MOUSE
θ value	6.88961 (rank : 122)	NC score	0.021893 (rank : 251)
Query Neighborhood Hits	131	Target Neighborhood Hits	238	Shared Neighborhood Hits	16
SwissProt Accessions	Q80UG5, Q3URP2, Q80TM7, Q9QYX9	Gene names	Sept9, Kiaa0991, Sint1
Domain Architecture	No domain graphic available
Description	Septin-9 (SL3-3 integration site 1 protein).

TIP60_HUMAN
θ value	6.88961 (rank : 123)	NC score	0.016689 (rank : 260)
Query Neighborhood Hits	131	Target Neighborhood Hits	90	Shared Neighborhood Hits	11
SwissProt Accessions	Q92993, O95624, Q13430, Q6GSE8, Q9BWK7	Gene names	HTATIP, TIP60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60) (HIV-1 Tat interactive protein) (cPLA(2)-interacting protein).

TOPB1_MOUSE
θ value	6.88961 (rank : 124)	NC score	0.013445 (rank : 268)
Query Neighborhood Hits	131	Target Neighborhood Hits	89	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZQF0, Q6P6P0, Q80Y33, Q8BUI0, Q8BUK1, Q8R348, Q91VX3, Q922X8	Gene names	Topbp1, Kiaa0259
Domain Architecture	No domain graphic available
Description	DNA topoisomerase II-binding protein 1 (DNA topoisomerase IIbeta- binding protein 1) (TopBP1).

BPAEA_HUMAN
θ value	8.99809 (rank : 125)	NC score	0.039432 (rank : 225)
Query Neighborhood Hits	131	Target Neighborhood Hits	1369	Shared Neighborhood Hits	39
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CD2L7_HUMAN
θ value	8.99809 (rank : 126)	NC score	0.011215 (rank : 271)
Query Neighborhood Hits	131	Target Neighborhood Hits	1275	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

LARP1_HUMAN
θ value	8.99809 (rank : 127)	NC score	0.021776 (rank : 252)
Query Neighborhood Hits	131	Target Neighborhood Hits	242	Shared Neighborhood Hits	15
SwissProt Accessions	Q6PKG0, O94836, Q8N4M2, Q8NB73, Q9UFD7	Gene names	LARP1, KIAA0731, LARP
Domain Architecture	No domain graphic available
Description	La-related protein 1 (La ribonucleoprotein domain family member 1).

LTB1L_HUMAN
θ value	8.99809 (rank : 128)	NC score	0.000973 (rank : 278)
Query Neighborhood Hits	131	Target Neighborhood Hits	553	Shared Neighborhood Hits	9
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

PITM3_HUMAN
θ value	8.99809 (rank : 129)	NC score	0.029698 (rank : 238)
Query Neighborhood Hits	131	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BZ71, Q59GH9, Q9NPQ4	Gene names	PITPNM3, NIR1
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 3 (Phosphatidylinositol transfer protein, membrane-associated 3) (Pyk2 N-terminal domain-interacting receptor 1) (NIR-1).

RUNX1_MOUSE
θ value	8.99809 (rank : 130)	NC score	0.018954 (rank : 257)
Query Neighborhood Hits	131	Target Neighborhood Hits	93	Shared Neighborhood Hits	7
SwissProt Accessions	Q03347, O08598, Q62049, Q9ESB9, Q9ET65	Gene names	Runx1, Aml1, Cbfa2, Pebp2ab
Domain Architecture
Description	Runt-related transcription factor 1 (Core-binding factor, alpha 2 subunit) (CBF-alpha 2) (Acute myeloid leukemia 1 protein) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEBP2-alpha B) (PEA2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit).

TFE3_HUMAN
θ value	8.99809 (rank : 131)	NC score	0.016673 (rank : 261)
Query Neighborhood Hits	131	Target Neighborhood Hits	190	Shared Neighborhood Hits	10
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

ABI1_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.056090 (rank : 118)
Query Neighborhood Hits	131	Target Neighborhood Hits	257	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

ABI1_MOUSE
θ value	θ > 10 (rank : 133)	NC score	0.055181 (rank : 129)
Query Neighborhood Hits	131	Target Neighborhood Hits	246	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

ABI2_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.059840 (rank : 91)
Query Neighborhood Hits	131	Target Neighborhood Hits	350	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

ABI2_MOUSE
θ value	θ > 10 (rank : 135)	NC score	0.055665 (rank : 125)
Query Neighborhood Hits	131	Target Neighborhood Hits	266	Shared Neighborhood Hits	11
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

ABI3_HUMAN
θ value	θ > 10 (rank : 136)	NC score	0.056683 (rank : 115)
Query Neighborhood Hits	131	Target Neighborhood Hits	227	Shared Neighborhood Hits	17
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ABI3_MOUSE
θ value	θ > 10 (rank : 137)	NC score	0.055914 (rank : 119)
Query Neighborhood Hits	131	Target Neighborhood Hits	227	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ARHG1_HUMAN
θ value	θ > 10 (rank : 138)	NC score	0.078810 (rank : 35)
Query Neighborhood Hits	131	Target Neighborhood Hits	176	Shared Neighborhood Hits	13
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

ARHG1_MOUSE
θ value	θ > 10 (rank : 139)	NC score	0.078553 (rank : 36)
Query Neighborhood Hits	131	Target Neighborhood Hits	266	Shared Neighborhood Hits	14
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

ARHG2_HUMAN
θ value	θ > 10 (rank : 140)	NC score	0.067223 (rank : 63)
Query Neighborhood Hits	131	Target Neighborhood Hits	142	Shared Neighborhood Hits	6
SwissProt Accessions	Q92974, O75142, Q15079	Gene names	ARHGEF2, KIAA0651, LFP40
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (GEF-H1 protein) (Proliferating cell nucleolar antigen p40).

ARHG2_MOUSE
θ value	θ > 10 (rank : 141)	NC score	0.069079 (rank : 56)
Query Neighborhood Hits	131	Target Neighborhood Hits	120	Shared Neighborhood Hits	6
SwissProt Accessions	Q60875, O09115	Gene names	Arhgef2, Lbcl1, Lfc
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (Lymphoid blast crisis- like 1) (LBC'S first cousin) (Oncogene LFC) (RHOBIN).

ARHG3_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.083557 (rank : 28)
Query Neighborhood Hits	131	Target Neighborhood Hits	82	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

ARHG3_MOUSE
θ value	θ > 10 (rank : 143)	NC score	0.082606 (rank : 31)
Query Neighborhood Hits	131	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

ARHG4_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.064863 (rank : 74)
Query Neighborhood Hits	131	Target Neighborhood Hits	242	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG4_MOUSE
θ value	θ > 10 (rank : 145)	NC score	0.068045 (rank : 58)
Query Neighborhood Hits	131	Target Neighborhood Hits	185	Shared Neighborhood Hits	8
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG5_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.065008 (rank : 73)
Query Neighborhood Hits	131	Target Neighborhood Hits	172	Shared Neighborhood Hits	4
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

ARHG6_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.066982 (rank : 65)
Query Neighborhood Hits	131	Target Neighborhood Hits	376	Shared Neighborhood Hits	14
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

ARHG6_MOUSE
θ value	θ > 10 (rank : 148)	NC score	0.067047 (rank : 64)
Query Neighborhood Hits	131	Target Neighborhood Hits	394	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

ARHG7_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.064575 (rank : 75)
Query Neighborhood Hits	131	Target Neighborhood Hits	347	Shared Neighborhood Hits	9
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

ARHG7_MOUSE
θ value	θ > 10 (rank : 150)	NC score	0.067242 (rank : 62)
Query Neighborhood Hits	131	Target Neighborhood Hits	396	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

ARHG8_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.083872 (rank : 27)
Query Neighborhood Hits	131	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z628, Q12773, Q96D82, Q99903, Q9UEN6	Gene names	NET1, ARHGEF8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (p65 Net1 proto- oncogene) (Rho guanine nucleotide exchange factor 8).

ARHG8_MOUSE
θ value	θ > 10 (rank : 152)	NC score	0.083037 (rank : 30)
Query Neighborhood Hits	131	Target Neighborhood Hits	79	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z206, Q8C4I0, Q9Z1L7	Gene names	Net1, Arhgef8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (Rho guanine nucleotide exchange factor 8).

ARHG9_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.066201 (rank : 67)
Query Neighborhood Hits	131	Target Neighborhood Hits	235	Shared Neighborhood Hits	9
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

ARHG9_MOUSE
θ value	θ > 10 (rank : 154)	NC score	0.066136 (rank : 68)
Query Neighborhood Hits	131	Target Neighborhood Hits	234	Shared Neighborhood Hits	9
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

ARHGA_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.067341 (rank : 61)
Query Neighborhood Hits	131	Target Neighborhood Hits	187	Shared Neighborhood Hits	8
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ARHGA_MOUSE
θ value	θ > 10 (rank : 156)	NC score	0.069363 (rank : 55)
Query Neighborhood Hits	131	Target Neighborhood Hits	125	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ARHGB_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.077770 (rank : 38)
Query Neighborhood Hits	131	Target Neighborhood Hits	375	Shared Neighborhood Hits	13
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

ARHGC_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.074624 (rank : 45)
Query Neighborhood Hits	131	Target Neighborhood Hits	351	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGC_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.075805 (rank : 40)
Query Neighborhood Hits	131	Target Neighborhood Hits	344	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGF_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.087321 (rank : 24)
Query Neighborhood Hits	131	Target Neighborhood Hits	214	Shared Neighborhood Hits	20
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

ARHGG_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.081288 (rank : 32)
Query Neighborhood Hits	131	Target Neighborhood Hits	129	Shared Neighborhood Hits	8
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

ARHGG_MOUSE
θ value	θ > 10 (rank : 162)	NC score	0.084198 (rank : 25)
Query Neighborhood Hits	131	Target Neighborhood Hits	152	Shared Neighborhood Hits	7
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

ASPP1_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.050037 (rank : 200)
Query Neighborhood Hits	131	Target Neighborhood Hits	956	Shared Neighborhood Hits	37
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

AZI1_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.059523 (rank : 94)
Query Neighborhood Hits	131	Target Neighborhood Hits	1000	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

BRE1B_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.054874 (rank : 132)
Query Neighborhood Hits	131	Target Neighborhood Hits	1040	Shared Neighborhood Hits	37
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

BSN_MOUSE
θ value	θ > 10 (rank : 166)	NC score	0.055875 (rank : 122)
Query Neighborhood Hits	131	Target Neighborhood Hits	2057	Shared Neighborhood Hits	72
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CARD9_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.051914 (rank : 165)
Query Neighborhood Hits	131	Target Neighborhood Hits	602	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H257, Q5SXM6, Q9H854	Gene names	CARD9
Domain Architecture
Description	Caspase recruitment domain-containing protein 9 (hCARD9).

CCD13_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.051464 (rank : 175)
Query Neighborhood Hits	131	Target Neighborhood Hits	721	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IYE1	Gene names	CCDC13
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 13.

CCD21_MOUSE
θ value	θ > 10 (rank : 169)	NC score	0.056511 (rank : 116)
Query Neighborhood Hits	131	Target Neighborhood Hits	1135	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CCD27_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.052656 (rank : 153)
Query Neighborhood Hits	131	Target Neighborhood Hits	594	Shared Neighborhood Hits	25
SwissProt Accessions	Q2M243, Q5TBV3, Q96M50	Gene names	CCDC27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

CCD41_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.052534 (rank : 154)
Query Neighborhood Hits	131	Target Neighborhood Hits	1139	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

CCD96_MOUSE
θ value	θ > 10 (rank : 172)	NC score	0.063895 (rank : 77)
Query Neighborhood Hits	131	Target Neighborhood Hits	704	Shared Neighborhood Hits	44
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CCDC6_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.057814 (rank : 105)
Query Neighborhood Hits	131	Target Neighborhood Hits	723	Shared Neighborhood Hits	31
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

CCHCR_MOUSE
θ value	θ > 10 (rank : 174)	NC score	0.050696 (rank : 186)
Query Neighborhood Hits	131	Target Neighborhood Hits	932	Shared Neighborhood Hits	33
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

CD2AP_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.075428 (rank : 42)
Query Neighborhood Hits	131	Target Neighborhood Hits	315	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

CD2AP_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.077503 (rank : 39)
Query Neighborhood Hits	131	Target Neighborhood Hits	336	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

CDC37_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.052144 (rank : 162)
Query Neighborhood Hits	131	Target Neighborhood Hits	506	Shared Neighborhood Hits	18
SwissProt Accessions	Q16543	Gene names	CDC37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

CE152_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.050306 (rank : 194)
Query Neighborhood Hits	131	Target Neighborhood Hits	976	Shared Neighborhood Hits	33
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

CEP57_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.057476 (rank : 107)
Query Neighborhood Hits	131	Target Neighborhood Hits	576	Shared Neighborhood Hits	27
SwissProt Accessions	Q86XR8, Q14704, Q8IXP0, Q9BVF9	Gene names	CEP57, KIAA0092, TSP57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin) (FGF2-interacting protein).

CEP57_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.057848 (rank : 104)
Query Neighborhood Hits	131	Target Neighborhood Hits	580	Shared Neighborhood Hits	25
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

CK5P2_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.050057 (rank : 199)
Query Neighborhood Hits	131	Target Neighborhood Hits	1433	Shared Neighborhood Hits	43
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

CN145_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.050061 (rank : 198)
Query Neighborhood Hits	131	Target Neighborhood Hits	1196	Shared Neighborhood Hits	34
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

CNTRB_MOUSE
θ value	θ > 10 (rank : 183)	NC score	0.052249 (rank : 160)
Query Neighborhood Hits	131	Target Neighborhood Hits	1029	Shared Neighborhood Hits	42
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CP250_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.055110 (rank : 131)
Query Neighborhood Hits	131	Target Neighborhood Hits	1805	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

CT096_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.054286 (rank : 135)
Query Neighborhood Hits	131	Target Neighborhood Hits	438	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NUD7, Q8N840, Q8NAX5	Gene names	C20orf96
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf96.

CT2NL_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.058377 (rank : 100)
Query Neighborhood Hits	131	Target Neighborhood Hits	1059	Shared Neighborhood Hits	43
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CUTL1_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.050384 (rank : 192)
Query Neighborhood Hits	131	Target Neighborhood Hits	1574	Shared Neighborhood Hits	52
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

DNMBP_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.061268 (rank : 87)
Query Neighborhood Hits	131	Target Neighborhood Hits	413	Shared Neighborhood Hits	16
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

DNMBP_MOUSE
θ value	θ > 10 (rank : 189)	NC score	0.070042 (rank : 53)
Query Neighborhood Hits	131	Target Neighborhood Hits	435	Shared Neighborhood Hits	28
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

ECT2_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.051612 (rank : 171)
Query Neighborhood Hits	131	Target Neighborhood Hits	98	Shared Neighborhood Hits	7
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

EFS_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.050027 (rank : 202)
Query Neighborhood Hits	131	Target Neighborhood Hits	348	Shared Neighborhood Hits	23
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

ENAH_MOUSE
θ value	θ > 10 (rank : 192)	NC score	0.050573 (rank : 187)
Query Neighborhood Hits	131	Target Neighborhood Hits	919	Shared Neighborhood Hits	47
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

FA62A_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.052667 (rank : 152)
Query Neighborhood Hits	131	Target Neighborhood Hits	168	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

FA62A_MOUSE
θ value	θ > 10 (rank : 194)	NC score	0.051932 (rank : 163)
Query Neighborhood Hits	131	Target Neighborhood Hits	155	Shared Neighborhood Hits	6
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

FGD6_MOUSE
θ value	θ > 10 (rank : 195)	NC score	0.058554 (rank : 99)
Query Neighborhood Hits	131	Target Neighborhood Hits	282	Shared Neighborhood Hits	13
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

GAS8_HUMAN
θ value	θ > 10 (rank : 196)	NC score	0.050434 (rank : 190)
Query Neighborhood Hits	131	Target Neighborhood Hits	819	Shared Neighborhood Hits	28
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

GNRP_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.054220 (rank : 137)
Query Neighborhood Hits	131	Target Neighborhood Hits	239	Shared Neighborhood Hits	9
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

GNRP_MOUSE
θ value	θ > 10 (rank : 198)	NC score	0.053134 (rank : 147)
Query Neighborhood Hits	131	Target Neighborhood Hits	191	Shared Neighborhood Hits	8
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

GOGA1_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.052482 (rank : 155)
Query Neighborhood Hits	131	Target Neighborhood Hits	1222	Shared Neighborhood Hits	38
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

GOGA1_MOUSE
θ value	θ > 10 (rank : 200)	NC score	0.051554 (rank : 173)
Query Neighborhood Hits	131	Target Neighborhood Hits	994	Shared Neighborhood Hits	33
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

GOGA5_MOUSE
θ value	θ > 10 (rank : 201)	NC score	0.051769 (rank : 168)
Query Neighborhood Hits	131	Target Neighborhood Hits	1434	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

GOGA6_HUMAN
θ value	θ > 10 (rank : 202)	NC score	0.050034 (rank : 201)
Query Neighborhood Hits	131	Target Neighborhood Hits	1007	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

GRAP1_MOUSE
θ value	θ > 10 (rank : 203)	NC score	0.052390 (rank : 157)
Query Neighborhood Hits	131	Target Neighborhood Hits	1234	Shared Neighborhood Hits	39
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

GRAP_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.052348 (rank : 159)
Query Neighborhood Hits	131	Target Neighborhood Hits	307	Shared Neighborhood Hits	11
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

GRAP_MOUSE
θ value	θ > 10 (rank : 205)	NC score	0.052373 (rank : 158)
Query Neighborhood Hits	131	Target Neighborhood Hits	309	Shared Neighborhood Hits	11
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

HCLS1_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.057848 (rank : 103)
Query Neighborhood Hits	131	Target Neighborhood Hits	358	Shared Neighborhood Hits	20
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

HCLS1_MOUSE
θ value	θ > 10 (rank : 207)	NC score	0.057782 (rank : 106)
Query Neighborhood Hits	131	Target Neighborhood Hits	329	Shared Neighborhood Hits	17
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

HIP1_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.053966 (rank : 138)
Query Neighborhood Hits	131	Target Neighborhood Hits	1016	Shared Neighborhood Hits	33
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

IFT74_HUMAN
θ value	θ > 10 (rank : 209)	NC score	0.056200 (rank : 117)
Query Neighborhood Hits	131	Target Neighborhood Hits	949	Shared Neighborhood Hits	30
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

IFT74_MOUSE
θ value	θ > 10 (rank : 210)	NC score	0.050180 (rank : 197)
Query Neighborhood Hits	131	Target Neighborhood Hits	939	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

IFT81_MOUSE
θ value	θ > 10 (rank : 211)	NC score	0.051245 (rank : 179)
Query Neighborhood Hits	131	Target Neighborhood Hits	959	Shared Neighborhood Hits	31
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

INVO_MOUSE
θ value	θ > 10 (rank : 212)	NC score	0.050985 (rank : 182)
Query Neighborhood Hits	131	Target Neighborhood Hits	474	Shared Neighborhood Hits	33
SwissProt Accessions	P48997	Gene names	Ivl
Domain Architecture	No domain graphic available
Description	Involucrin.

K0555_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.051282 (rank : 178)
Query Neighborhood Hits	131	Target Neighborhood Hits	880	Shared Neighborhood Hits	33
SwissProt Accessions	Q96AA8, O60302	Gene names	KIAA0555
Domain Architecture	No domain graphic available
Description	Protein KIAA0555.

LBC_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.065447 (rank : 70)
Query Neighborhood Hits	131	Target Neighborhood Hits	90	Shared Neighborhood Hits	6
SwissProt Accessions	Q12802	Gene names	LBC
Domain Architecture
Description	LBC oncogene (P47) (Lymphoid blast crisis oncogene).

LZTS1_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.053394 (rank : 143)
Query Neighborhood Hits	131	Target Neighborhood Hits	532	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y250, Q9Y5V7, Q9Y5V8, Q9Y5V9, Q9Y5W0, Q9Y5W1, Q9Y5W2	Gene names	LZTS1, FEZ1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

LZTS1_MOUSE
θ value	θ > 10 (rank : 216)	NC score	0.051389 (rank : 177)
Query Neighborhood Hits	131	Target Neighborhood Hits	540	Shared Neighborhood Hits	25
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

MD1L1_MOUSE
θ value	θ > 10 (rank : 217)	NC score	0.053627 (rank : 140)
Query Neighborhood Hits	131	Target Neighborhood Hits	1001	Shared Neighborhood Hits	32
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

MDC1_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.055567 (rank : 127)
Query Neighborhood Hits	131	Target Neighborhood Hits	1446	Shared Neighborhood Hits	62
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MLL2_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.052714 (rank : 151)
Query Neighborhood Hits	131	Target Neighborhood Hits	1788	Shared Neighborhood Hits	71
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MUC7_HUMAN
θ value	θ > 10 (rank : 220)	NC score	0.055879 (rank : 121)
Query Neighborhood Hits	131	Target Neighborhood Hits	538	Shared Neighborhood Hits	39
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

NAF1_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.050396 (rank : 191)
Query Neighborhood Hits	131	Target Neighborhood Hits	937	Shared Neighborhood Hits	35
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

NCF1_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.074197 (rank : 47)
Query Neighborhood Hits	131	Target Neighborhood Hits	198	Shared Neighborhood Hits	9
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

NCF1_MOUSE
θ value	θ > 10 (rank : 223)	NC score	0.077894 (rank : 37)
Query Neighborhood Hits	131	Target Neighborhood Hits	198	Shared Neighborhood Hits	9
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

NCF2_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.065809 (rank : 69)
Query Neighborhood Hits	131	Target Neighborhood Hits	229	Shared Neighborhood Hits	7
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

NCF4_HUMAN
θ value	θ > 10 (rank : 225)	NC score	0.055875 (rank : 123)
Query Neighborhood Hits	131	Target Neighborhood Hits	161	Shared Neighborhood Hits	6
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

NCF4_MOUSE
θ value	θ > 10 (rank : 226)	NC score	0.050879 (rank : 184)
Query Neighborhood Hits	131	Target Neighborhood Hits	177	Shared Neighborhood Hits	6
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

NCK1_HUMAN
θ value	θ > 10 (rank : 227)	NC score	0.072790 (rank : 48)
Query Neighborhood Hits	131	Target Neighborhood Hits	312	Shared Neighborhood Hits	11
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

NCK2_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.067625 (rank : 59)
Query Neighborhood Hits	131	Target Neighborhood Hits	310	Shared Neighborhood Hits	12
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

NEB2_MOUSE
θ value	θ > 10 (rank : 229)	NC score	0.053922 (rank : 139)
Query Neighborhood Hits	131	Target Neighborhood Hits	889	Shared Neighborhood Hits	37
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEMO_HUMAN
θ value	θ > 10 (rank : 230)	NC score	0.051419 (rank : 176)
Query Neighborhood Hits	131	Target Neighborhood Hits	820	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

NEST_HUMAN
θ value	θ > 10 (rank : 231)	NC score	0.051924 (rank : 164)
Query Neighborhood Hits	131	Target Neighborhood Hits	1305	Shared Neighborhood Hits	49
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

NGEF_HUMAN
θ value	θ > 10 (rank : 232)	NC score	0.075559 (rank : 41)
Query Neighborhood Hits	131	Target Neighborhood Hits	166	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

NGEF_MOUSE
θ value	θ > 10 (rank : 233)	NC score	0.079137 (rank : 34)
Query Neighborhood Hits	131	Target Neighborhood Hits	228	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

NOLC1_HUMAN
θ value	θ > 10 (rank : 234)	NC score	0.057063 (rank : 111)
Query Neighborhood Hits	131	Target Neighborhood Hits	452	Shared Neighborhood Hits	36
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

NOXO1_HUMAN
θ value	θ > 10 (rank : 235)	NC score	0.065052 (rank : 72)
Query Neighborhood Hits	131	Target Neighborhood Hits	100	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NFA2, Q86YM1, Q8NFA3, Q96B73	Gene names	NOXO1, P41NOX
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Nox-organizing protein 1) (NADPH oxidase regulatory protein).

NOXO1_MOUSE
θ value	θ > 10 (rank : 236)	NC score	0.070102 (rank : 52)
Query Neighborhood Hits	131	Target Neighborhood Hits	114	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VCM2, Q3TZA4, Q8BH41, Q9D747	Gene names	Noxo1, Snx28
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Sorting nexin-28).

NUCB2_MOUSE
θ value	θ > 10 (rank : 237)	NC score	0.050014 (rank : 204)
Query Neighborhood Hits	131	Target Neighborhood Hits	459	Shared Neighborhood Hits	23
SwissProt Accessions	P81117	Gene names	Nucb2, Nefa
Domain Architecture	No domain graphic available
Description	Nucleobindin-2 precursor (DNA-binding protein NEFA).

OPTN_HUMAN
θ value	θ > 10 (rank : 238)	NC score	0.050500 (rank : 188)
Query Neighborhood Hits	131	Target Neighborhood Hits	827	Shared Neighborhood Hits	31
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

PCQAP_HUMAN
θ value	θ > 10 (rank : 239)	NC score	0.059286 (rank : 96)
Query Neighborhood Hits	131	Target Neighborhood Hits	549	Shared Neighborhood Hits	35
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

PCQAP_MOUSE
θ value	θ > 10 (rank : 240)	NC score	0.067352 (rank : 60)
Query Neighborhood Hits	131	Target Neighborhood Hits	506	Shared Neighborhood Hits	35
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

PKHG1_HUMAN
θ value	θ > 10 (rank : 241)	NC score	0.051497 (rank : 174)
Query Neighborhood Hits	131	Target Neighborhood Hits	174	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

PREX1_HUMAN
θ value	θ > 10 (rank : 242)	NC score	0.055306 (rank : 128)
Query Neighborhood Hits	131	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

RABE1_HUMAN
θ value	θ > 10 (rank : 243)	NC score	0.050446 (rank : 189)
Query Neighborhood Hits	131	Target Neighborhood Hits	1104	Shared Neighborhood Hits	33
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

RABE2_HUMAN
θ value	θ > 10 (rank : 244)	NC score	0.051789 (rank : 167)
Query Neighborhood Hits	131	Target Neighborhood Hits	545	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H5N1	Gene names	RABEP2, RABPT5B
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

RFIP3_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.059217 (rank : 97)
Query Neighborhood Hits	131	Target Neighborhood Hits	1055	Shared Neighborhood Hits	40
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

RFIP4_HUMAN
θ value	θ > 10 (rank : 246)	NC score	0.051699 (rank : 169)
Query Neighborhood Hits	131	Target Neighborhood Hits	785	Shared Neighborhood Hits	31
SwissProt Accessions	Q86YS3, Q8N829, Q8NDT7, Q969D8	Gene names	RAB11FIP4, KIAA1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

RGNEF_MOUSE
θ value	θ > 10 (rank : 247)	NC score	0.075245 (rank : 43)
Query Neighborhood Hits	131	Target Neighborhood Hits	641	Shared Neighborhood Hits	22
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

RIMB1_HUMAN
θ value	θ > 10 (rank : 248)	NC score	0.052470 (rank : 156)
Query Neighborhood Hits	131	Target Neighborhood Hits	1479	Shared Neighborhood Hits	55
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SAS6_MOUSE
θ value	θ > 10 (rank : 249)	NC score	0.051575 (rank : 172)
Query Neighborhood Hits	131	Target Neighborhood Hits	931	Shared Neighborhood Hits	32
SwissProt Accessions	Q80UK7, Q9CYT4	Gene names	Sass6, Sas6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog.

SDCG8_HUMAN
θ value	θ > 10 (rank : 250)	NC score	0.054226 (rank : 136)
Query Neighborhood Hits	131	Target Neighborhood Hits	1002	Shared Neighborhood Hits	36
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

SH3K1_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.083149 (rank : 29)
Query Neighborhood Hits	131	Target Neighborhood Hits	341	Shared Neighborhood Hits	18
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

SH3K1_MOUSE
θ value	θ > 10 (rank : 252)	NC score	0.070648 (rank : 51)
Query Neighborhood Hits	131	Target Neighborhood Hits	332	Shared Neighborhood Hits	17
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

SMC2_HUMAN
θ value	θ > 10 (rank : 253)	NC score	0.050333 (rank : 193)
Query Neighborhood Hits	131	Target Neighborhood Hits	1405	Shared Neighborhood Hits	41
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

SRBS1_HUMAN
θ value	θ > 10 (rank : 254)	NC score	0.059931 (rank : 90)
Query Neighborhood Hits	131	Target Neighborhood Hits	396	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SRBS1_MOUSE
θ value	θ > 10 (rank : 255)	NC score	0.072388 (rank : 50)
Query Neighborhood Hits	131	Target Neighborhood Hits	409	Shared Neighborhood Hits	20
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SRCA_HUMAN
θ value	θ > 10 (rank : 256)	NC score	0.193654 (rank : 21)
Query Neighborhood Hits	131	Target Neighborhood Hits	380	Shared Neighborhood Hits	24
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

SRCA_MOUSE
θ value	θ > 10 (rank : 257)	NC score	0.200126 (rank : 20)
Query Neighborhood Hits	131	Target Neighborhood Hits	212	Shared Neighborhood Hits	14
SwissProt Accessions	Q7TQ48, Q8BS43	Gene names	Srl, Sar
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

SRRM1_HUMAN
θ value	θ > 10 (rank : 258)	NC score	0.056886 (rank : 113)
Query Neighborhood Hits	131	Target Neighborhood Hits	690	Shared Neighborhood Hits	48
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRRM2_HUMAN
θ value	θ > 10 (rank : 259)	NC score	0.053382 (rank : 144)
Query Neighborhood Hits	131	Target Neighborhood Hits	1296	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

STAC3_HUMAN
θ value	θ > 10 (rank : 260)	NC score	0.052972 (rank : 149)
Query Neighborhood Hits	131	Target Neighborhood Hits	228	Shared Neighborhood Hits	10
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_MOUSE
θ value	θ > 10 (rank : 261)	NC score	0.053203 (rank : 146)
Query Neighborhood Hits	131	Target Neighborhood Hits	232	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAM1_HUMAN
θ value	θ > 10 (rank : 262)	NC score	0.051886 (rank : 166)
Query Neighborhood Hits	131	Target Neighborhood Hits	271	Shared Neighborhood Hits	11
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM1_MOUSE
θ value	θ > 10 (rank : 263)	NC score	0.053480 (rank : 141)
Query Neighborhood Hits	131	Target Neighborhood Hits	273	Shared Neighborhood Hits	11
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM2_MOUSE
θ value	θ > 10 (rank : 264)	NC score	0.051049 (rank : 181)
Query Neighborhood Hits	131	Target Neighborhood Hits	285	Shared Neighborhood Hits	11
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

SWP70_MOUSE
θ value	θ > 10 (rank : 265)	NC score	0.051202 (rank : 180)
Query Neighborhood Hits	131	Target Neighborhood Hits	1097	Shared Neighborhood Hits	33
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

TAXB1_HUMAN
θ value	θ > 10 (rank : 266)	NC score	0.055128 (rank : 130)
Query Neighborhood Hits	131	Target Neighborhood Hits	829	Shared Neighborhood Hits	28
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

TCRG1_MOUSE
θ value	θ > 10 (rank : 267)	NC score	0.050762 (rank : 185)
Query Neighborhood Hits	131	Target Neighborhood Hits	947	Shared Neighborhood Hits	44
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TIAM1_HUMAN
θ value	θ > 10 (rank : 268)	NC score	0.062765 (rank : 81)
Query Neighborhood Hits	131	Target Neighborhood Hits	225	Shared Neighborhood Hits	6
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TIAM1_MOUSE
θ value	θ > 10 (rank : 269)	NC score	0.065309 (rank : 71)
Query Neighborhood Hits	131	Target Neighborhood Hits	205	Shared Neighborhood Hits	5
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TRAIP_HUMAN
θ value	θ > 10 (rank : 270)	NC score	0.050015 (rank : 203)
Query Neighborhood Hits	131	Target Neighborhood Hits	780	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TRAIP_MOUSE
θ value	θ > 10 (rank : 271)	NC score	0.058196 (rank : 101)
Query Neighborhood Hits	131	Target Neighborhood Hits	745	Shared Neighborhood Hits	30
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

TSC1_HUMAN
θ value	θ > 10 (rank : 272)	NC score	0.056757 (rank : 114)
Query Neighborhood Hits	131	Target Neighborhood Hits	765	Shared Neighborhood Hits	35
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

TUFT1_HUMAN
θ value	θ > 10 (rank : 273)	NC score	0.063253 (rank : 80)
Query Neighborhood Hits	131	Target Neighborhood Hits	686	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

TUFT1_MOUSE
θ value	θ > 10 (rank : 274)	NC score	0.057318 (rank : 109)
Query Neighborhood Hits	131	Target Neighborhood Hits	732	Shared Neighborhood Hits	31
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

VINEX_HUMAN
θ value	θ > 10 (rank : 275)	NC score	0.069365 (rank : 54)
Query Neighborhood Hits	131	Target Neighborhood Hits	270	Shared Neighborhood Hits	11
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

VINEX_MOUSE
θ value	θ > 10 (rank : 276)	NC score	0.068902 (rank : 57)
Query Neighborhood Hits	131	Target Neighborhood Hits	286	Shared Neighborhood Hits	12
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

WBP11_HUMAN
θ value	θ > 10 (rank : 277)	NC score	0.052227 (rank : 161)
Query Neighborhood Hits	131	Target Neighborhood Hits	354	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

WBP11_MOUSE
θ value	θ > 10 (rank : 278)	NC score	0.053411 (rank : 142)
Query Neighborhood Hits	131	Target Neighborhood Hits	362	Shared Neighborhood Hits	24
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

Hits sorted by NC score

REPS2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	131	Target Neighborhood Hits	131	Shared Neighborhood Hits	131
SwissProt Accessions	Q8NFH8, O43428, Q8NFI5	Gene names	REPS2, POB1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

REPS2_MOUSE
NC score	0.967026 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	131	Target Neighborhood Hits	102	Shared Neighborhood Hits	56
SwissProt Accessions	Q80XA6	Gene names	Reps2, Pob1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

REPS1_MOUSE
NC score	0.836309 (rank : 3)	θ value	8.24801e-70 (rank : 3)
Query Neighborhood Hits	131	Target Neighborhood Hits	204	Shared Neighborhood Hits	31
SwissProt Accessions	O54916, Q8C9J9, Q99LR8	Gene names	Reps1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

REPS1_HUMAN
NC score	0.828145 (rank : 4)	θ value	5.37103e-53 (rank : 4)
Query Neighborhood Hits	131	Target Neighborhood Hits	205	Shared Neighborhood Hits	36
SwissProt Accessions	Q96D71, Q8NDR7, Q8WU62, Q9BXY9	Gene names	REPS1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

EHD4_MOUSE
NC score	0.520896 (rank : 5)	θ value	3.89403e-11 (rank : 10)
Query Neighborhood Hits	131	Target Neighborhood Hits	40	Shared Neighborhood Hits	21
SwissProt Accessions	Q9EQP2	Gene names	Ehd4, Past2
Domain Architecture
Description	EH-domain-containing protein 4 (mPAST2).

EHD4_HUMAN
NC score	0.516525 (rank : 6)	θ value	3.89403e-11 (rank : 9)
Query Neighborhood Hits	131	Target Neighborhood Hits	41	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H223, Q9HAR1, Q9NZN2	Gene names	EHD4, HCA10, HCA11
Domain Architecture
Description	EH-domain-containing protein 4 (Hepatocellular carcinoma-associated protein 10/11).

EHD2_HUMAN
NC score	0.515413 (rank : 7)	θ value	3.64472e-09 (rank : 15)
Query Neighborhood Hits	131	Target Neighborhood Hits	29	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NZN4, Q96CB6	Gene names	EHD2
Domain Architecture
Description	EH-domain-containing protein 2.

EHD1_HUMAN
NC score	0.506406 (rank : 8)	θ value	4.0297e-08 (rank : 16)
Query Neighborhood Hits	131	Target Neighborhood Hits	36	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H4M9, O14611, Q9UNR3	Gene names	EHD1, PAST, PAST1
Domain Architecture
Description	EH-domain-containing protein 1 (Testilin) (hPAST1).

EHD1_MOUSE
NC score	0.505824 (rank : 9)	θ value	5.26297e-08 (rank : 17)
Query Neighborhood Hits	131	Target Neighborhood Hits	37	Shared Neighborhood Hits	21
SwissProt Accessions	Q9WVK4	Gene names	Ehd1, Past1
Domain Architecture
Description	EH-domain-containing protein 1 (mPAST1).

EHD3_MOUSE
NC score	0.501629 (rank : 10)	θ value	1.17247e-07 (rank : 18)
Query Neighborhood Hits	131	Target Neighborhood Hits	34	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QXY6	Gene names	Ehd3, Ehd2
Domain Architecture
Description	EH-domain-containing protein 3.

EHD3_HUMAN
NC score	0.498063 (rank : 11)	θ value	5.81887e-07 (rank : 19)
Query Neighborhood Hits	131	Target Neighborhood Hits	33	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NZN3, Q8N514, Q9NZB3	Gene names	EHD3, EHD2
Domain Architecture
Description	EH-domain-containing protein 3.

EP15_MOUSE
NC score	0.389606 (rank : 12)	θ value	1.133e-10 (rank : 11)
Query Neighborhood Hits	131	Target Neighborhood Hits	820	Shared Neighborhood Hits	42
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

EP15_HUMAN
NC score	0.373013 (rank : 13)	θ value	1.47974e-10 (rank : 12)
Query Neighborhood Hits	131	Target Neighborhood Hits	1021	Shared Neighborhood Hits	45
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

EP15R_MOUSE
NC score	0.336604 (rank : 14)	θ value	1.25267e-09 (rank : 14)
Query Neighborhood Hits	131	Target Neighborhood Hits	1135	Shared Neighborhood Hits	53
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

EP15R_HUMAN
NC score	0.331262 (rank : 15)	θ value	3.29651e-10 (rank : 13)
Query Neighborhood Hits	131	Target Neighborhood Hits	1083	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

ITSN2_HUMAN
NC score	0.299297 (rank : 16)	θ value	5.8054e-15 (rank : 5)
Query Neighborhood Hits	131	Target Neighborhood Hits	1173	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

ITSN2_MOUSE
NC score	0.288696 (rank : 17)	θ value	4.91457e-14 (rank : 6)
Query Neighborhood Hits	131	Target Neighborhood Hits	1371	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

ITSN1_MOUSE
NC score	0.285919 (rank : 18)	θ value	8.38298e-14 (rank : 7)
Query Neighborhood Hits	131	Target Neighborhood Hits	1669	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

ITSN1_HUMAN
NC score	0.284012 (rank : 19)	θ value	2.43908e-13 (rank : 8)
Query Neighborhood Hits	131	Target Neighborhood Hits	1757	Shared Neighborhood Hits	62
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

SRCA_MOUSE
NC score	0.200126 (rank : 20)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	131	Target Neighborhood Hits	212	Shared Neighborhood Hits	14
SwissProt Accessions	Q7TQ48, Q8BS43	Gene names	Srl, Sar
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

SRCA_HUMAN
NC score	0.193654 (rank : 21)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	131	Target Neighborhood Hits	380	Shared Neighborhood Hits	24
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

SYNG_MOUSE
NC score	0.135717 (rank : 22)	θ value	1.06291 (rank : 58)
Query Neighborhood Hits	131	Target Neighborhood Hits	206	Shared Neighborhood Hits	27
SwissProt Accessions	Q5SV85, Q5SV84, Q6PHT6	Gene names	Ap1gbp1, Syng
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

SYNG_HUMAN
NC score	0.120107 (rank : 23)	θ value	1.06291 (rank : 57)
Query Neighborhood Hits	131	Target Neighborhood Hits	160	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UMZ2, Q6ZT17	Gene names	AP1GBP1, SYNG
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

ARHGF_HUMAN
NC score	0.087321 (rank : 24)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	131	Target Neighborhood Hits	214	Shared Neighborhood Hits	20
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

ARHGG_MOUSE
NC score	0.084198 (rank : 25)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	131	Target Neighborhood Hits	152	Shared Neighborhood Hits	7
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

GOGA2_MOUSE
NC score	0.083987 (rank : 26)	θ value	0.279714 (rank : 34)
Query Neighborhood Hits	131	Target Neighborhood Hits	944	Shared Neighborhood Hits	36
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

ARHG8_HUMAN
NC score	0.083872 (rank : 27)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	131	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z628, Q12773, Q96D82, Q99903, Q9UEN6	Gene names	NET1, ARHGEF8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (p65 Net1 proto- oncogene) (Rho guanine nucleotide exchange factor 8).

ARHG3_HUMAN
NC score	0.083557 (rank : 28)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	131	Target Neighborhood Hits	82	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

SH3K1_HUMAN
NC score	0.083149 (rank : 29)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	131	Target Neighborhood Hits	341	Shared Neighborhood Hits	18
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

ARHG8_MOUSE
NC score	0.083037 (rank : 30)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	131	Target Neighborhood Hits	79	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z206, Q8C4I0, Q9Z1L7	Gene names	Net1, Arhgef8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (Rho guanine nucleotide exchange factor 8).

ARHG3_MOUSE
NC score	0.082606 (rank : 31)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	131	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

ARHGG_HUMAN
NC score	0.081288 (rank : 32)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	131	Target Neighborhood Hits	129	Shared Neighborhood Hits	8
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

BLNK_MOUSE
NC score	0.080993 (rank : 33)	θ value	0.0563607 (rank : 22)
Query Neighborhood Hits	131	Target Neighborhood Hits	296	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

NGEF_MOUSE
NC score	0.079137 (rank : 34)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	131	Target Neighborhood Hits	228	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

ARHG1_HUMAN
NC score	0.078810 (rank : 35)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	131	Target Neighborhood Hits	176	Shared Neighborhood Hits	13
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

ARHG1_MOUSE
NC score	0.078553 (rank : 36)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	131	Target Neighborhood Hits	266	Shared Neighborhood Hits	14
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

NCF1_MOUSE
NC score	0.077894 (rank : 37)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	131	Target Neighborhood Hits	198	Shared Neighborhood Hits	9
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

ARHGB_HUMAN
NC score	0.077770 (rank : 38)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	131	Target Neighborhood Hits	375	Shared Neighborhood Hits	13
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

CD2AP_MOUSE
NC score	0.077503 (rank : 39)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	131	Target Neighborhood Hits	336	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

ARHGC_MOUSE
NC score	0.075805 (rank : 40)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	131	Target Neighborhood Hits	344	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

NGEF_HUMAN
NC score	0.075559 (rank : 41)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	131	Target Neighborhood Hits	166	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

CD2AP_HUMAN
NC score	0.075428 (rank : 42)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	131	Target Neighborhood Hits	315	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

RGNEF_MOUSE
NC score	0.075245 (rank : 43)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	131	Target Neighborhood Hits	641	Shared Neighborhood Hits	22
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

GOGA2_HUMAN
NC score	0.074945 (rank : 44)	θ value	0.279714 (rank : 33)
Query Neighborhood Hits	131	Target Neighborhood Hits	856	Shared Neighborhood Hits	33
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

ARHGC_HUMAN
NC score	0.074624 (rank : 45)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	131	Target Neighborhood Hits	351	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

PCLO_HUMAN
NC score	0.074531 (rank : 46)	θ value	1.06291 (rank : 55)
Query Neighborhood Hits	131	Target Neighborhood Hits	2046	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

NCF1_HUMAN
NC score	0.074197 (rank : 47)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	131	Target Neighborhood Hits	198	Shared Neighborhood Hits	9
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

NCK1_HUMAN
NC score	0.072790 (rank : 48)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	131	Target Neighborhood Hits	312	Shared Neighborhood Hits	11
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

SELPL_MOUSE
NC score	0.072679 (rank : 49)	θ value	0.0563607 (rank : 23)
Query Neighborhood Hits	131	Target Neighborhood Hits	588	Shared Neighborhood Hits	41
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SRBS1_MOUSE
NC score	0.072388 (rank : 50)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	131	Target Neighborhood Hits	409	Shared Neighborhood Hits	20
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SH3K1_MOUSE
NC score	0.070648 (rank : 51)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	131	Target Neighborhood Hits	332	Shared Neighborhood Hits	17
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

NOXO1_MOUSE
NC score	0.070102 (rank : 52)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	131	Target Neighborhood Hits	114	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VCM2, Q3TZA4, Q8BH41, Q9D747	Gene names	Noxo1, Snx28
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Sorting nexin-28).

DNMBP_MOUSE
NC score	0.070042 (rank : 53)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	131	Target Neighborhood Hits	435	Shared Neighborhood Hits	28
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

VINEX_HUMAN
NC score	0.069365 (rank : 54)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	131	Target Neighborhood Hits	270	Shared Neighborhood Hits	11
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

ARHGA_MOUSE
NC score	0.069363 (rank : 55)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	131	Target Neighborhood Hits	125	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ARHG2_MOUSE
NC score	0.069079 (rank : 56)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	131	Target Neighborhood Hits	120	Shared Neighborhood Hits	6
SwissProt Accessions	Q60875, O09115	Gene names	Arhgef2, Lbcl1, Lfc
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (Lymphoid blast crisis- like 1) (LBC'S first cousin) (Oncogene LFC) (RHOBIN).

VINEX_MOUSE
NC score	0.068902 (rank : 57)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	131	Target Neighborhood Hits	286	Shared Neighborhood Hits	12
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

ARHG4_MOUSE
NC score	0.068045 (rank : 58)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	131	Target Neighborhood Hits	185	Shared Neighborhood Hits	8
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

NCK2_HUMAN
NC score	0.067625 (rank : 59)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	131	Target Neighborhood Hits	310	Shared Neighborhood Hits	12
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

PCQAP_MOUSE
NC score	0.067352 (rank : 60)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	131	Target Neighborhood Hits	506	Shared Neighborhood Hits	35
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

ARHGA_HUMAN
NC score	0.067341 (rank : 61)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	131	Target Neighborhood Hits	187	Shared Neighborhood Hits	8
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ARHG7_MOUSE
NC score	0.067242 (rank : 62)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	131	Target Neighborhood Hits	396	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

ARHG2_HUMAN
NC score	0.067223 (rank : 63)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	131	Target Neighborhood Hits	142	Shared Neighborhood Hits	6
SwissProt Accessions	Q92974, O75142, Q15079	Gene names	ARHGEF2, KIAA0651, LFP40
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (GEF-H1 protein) (Proliferating cell nucleolar antigen p40).

ARHG6_MOUSE
NC score	0.067047 (rank : 64)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	131	Target Neighborhood Hits	394	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

ARHG6_HUMAN
NC score	0.066982 (rank : 65)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	131	Target Neighborhood Hits	376	Shared Neighborhood Hits	14
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

CS016_HUMAN
NC score	0.066215 (rank : 66)	θ value	2.36792 (rank : 70)
Query Neighborhood Hits	131	Target Neighborhood Hits	310	Shared Neighborhood Hits	36
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

ARHG9_HUMAN
NC score	0.066201 (rank : 67)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	131	Target Neighborhood Hits	235	Shared Neighborhood Hits	9
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

ARHG9_MOUSE
NC score	0.066136 (rank : 68)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	131	Target Neighborhood Hits	234	Shared Neighborhood Hits	9
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

NCF2_HUMAN
NC score	0.065809 (rank : 69)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	131	Target Neighborhood Hits	229	Shared Neighborhood Hits	7
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

LBC_HUMAN
NC score	0.065447 (rank : 70)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	131	Target Neighborhood Hits	90	Shared Neighborhood Hits	6
SwissProt Accessions	Q12802	Gene names	LBC
Domain Architecture
Description	LBC oncogene (P47) (Lymphoid blast crisis oncogene).

TIAM1_MOUSE
NC score	0.065309 (rank : 71)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	131	Target Neighborhood Hits	205	Shared Neighborhood Hits	5
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

NOXO1_HUMAN
NC score	0.065052 (rank : 72)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	131	Target Neighborhood Hits	100	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NFA2, Q86YM1, Q8NFA3, Q96B73	Gene names	NOXO1, P41NOX
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Nox-organizing protein 1) (NADPH oxidase regulatory protein).

ARHG5_HUMAN
NC score	0.065008 (rank : 73)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	131	Target Neighborhood Hits	172	Shared Neighborhood Hits	4
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

ARHG4_HUMAN
NC score	0.064863 (rank : 74)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	131	Target Neighborhood Hits	242	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG7_HUMAN
NC score	0.064575 (rank : 75)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	131	Target Neighborhood Hits	347	Shared Neighborhood Hits	9
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

BSN_HUMAN
NC score	0.064462 (rank : 76)	θ value	1.06291 (rank : 52)
Query Neighborhood Hits	131	Target Neighborhood Hits	1537	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CCD96_MOUSE
NC score	0.063895 (rank : 77)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	131	Target Neighborhood Hits	704	Shared Neighborhood Hits	44
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

SRRM1_MOUSE
NC score	0.063661 (rank : 78)	θ value	0.62314 (rank : 43)
Query Neighborhood Hits	131	Target Neighborhood Hits	966	Shared Neighborhood Hits	54
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TRAK1_HUMAN
NC score	0.063468 (rank : 79)	θ value	3.0926 (rank : 89)
Query Neighborhood Hits	131	Target Neighborhood Hits	660	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UPV9, Q96B69	Gene names	TRAK1, KIAA1042, OIP106
Domain Architecture	No domain graphic available
Description	Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase- interacting protein).

TUFT1_HUMAN
NC score	0.063253 (rank : 80)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	131	Target Neighborhood Hits	686	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

TIAM1_HUMAN
NC score	0.062765 (rank : 81)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	131	Target Neighborhood Hits	225	Shared Neighborhood Hits	6
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

EFS_MOUSE
NC score	0.062761 (rank : 82)	θ value	4.03905 (rank : 93)
Query Neighborhood Hits	131	Target Neighborhood Hits	389	Shared Neighborhood Hits	25
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

SFRIP_HUMAN
NC score	0.062611 (rank : 83)	θ value	0.813845 (rank : 49)
Query Neighborhood Hits	131	Target Neighborhood Hits	530	Shared Neighborhood Hits	32
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

ATX7_HUMAN
NC score	0.061578 (rank : 84)	θ value	1.38821 (rank : 60)
Query Neighborhood Hits	131	Target Neighborhood Hits	351	Shared Neighborhood Hits	24
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

RS6_HUMAN
NC score	0.061404 (rank : 85)	θ value	1.81305 (rank : 66)
Query Neighborhood Hits	131	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	P62753, P08227, P10660, Q4VBY7, Q8N6Z7	Gene names	RPS6
Domain Architecture	No domain graphic available
Description	40S ribosomal protein S6 (Phosphoprotein NP33).

RS6_MOUSE
NC score	0.061404 (rank : 86)	θ value	1.81305 (rank : 67)
Query Neighborhood Hits	131	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	P62754, P08227, P10660	Gene names	Rps6
Domain Architecture	No domain graphic available
Description	40S ribosomal protein S6 (Phosphoprotein NP33).

DNMBP_HUMAN
NC score	0.061268 (rank : 87)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	131	Target Neighborhood Hits	413	Shared Neighborhood Hits	16
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

PCLO_MOUSE
NC score	0.061261 (rank : 88)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	131	Target Neighborhood Hits	2275	Shared Neighborhood Hits	76
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

ATX7_MOUSE
NC score	0.060346 (rank : 89)	θ value	0.21417 (rank : 29)
Query Neighborhood Hits	131	Target Neighborhood Hits	328	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

SRBS1_HUMAN
NC score	0.059931 (rank : 90)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	131	Target Neighborhood Hits	396	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

ABI2_HUMAN
NC score	0.059840 (rank : 91)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	131	Target Neighborhood Hits	350	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

RPGR1_MOUSE
NC score	0.059767 (rank : 92)	θ value	0.21417 (rank : 30)
Query Neighborhood Hits	131	Target Neighborhood Hits	713	Shared Neighborhood Hits	26
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

RPGR1_HUMAN
NC score	0.059640 (rank : 93)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	131	Target Neighborhood Hits	578	Shared Neighborhood Hits	31
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

AZI1_HUMAN
NC score	0.059523 (rank : 94)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	131	Target Neighborhood Hits	1000	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

MLL3_HUMAN
NC score	0.059504 (rank : 95)	θ value	1.06291 (rank : 53)
Query Neighborhood Hits	131	Target Neighborhood Hits	1644	Shared Neighborhood Hits	58
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PCQAP_HUMAN
NC score	0.059286 (rank : 96)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	131	Target Neighborhood Hits	549	Shared Neighborhood Hits	35
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

RFIP3_HUMAN
NC score	0.059217 (rank : 97)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	131	Target Neighborhood Hits	1055	Shared Neighborhood Hits	40
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

RGS3_MOUSE
NC score	0.058900 (rank : 98)	θ value	0.00102713 (rank : 20)
Query Neighborhood Hits	131	Target Neighborhood Hits	1621	Shared Neighborhood Hits	59
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

FGD6_MOUSE
NC score	0.058554 (rank : 99)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	131	Target Neighborhood Hits	282	Shared Neighborhood Hits	13
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

CT2NL_HUMAN
NC score	0.058377 (rank : 100)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	131	Target Neighborhood Hits	1059	Shared Neighborhood Hits	43
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

TRAIP_MOUSE
NC score	0.058196 (rank : 101)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	131	Target Neighborhood Hits	745	Shared Neighborhood Hits	30
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

ASPP1_MOUSE
NC score	0.058019 (rank : 102)	θ value	0.365318 (rank : 37)
Query Neighborhood Hits	131	Target Neighborhood Hits	1244	Shared Neighborhood Hits	53
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

HCLS1_HUMAN
NC score	0.057848 (rank : 103)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	131	Target Neighborhood Hits	358	Shared Neighborhood Hits	20
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

CEP57_MOUSE
NC score	0.057848 (rank : 104)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	131	Target Neighborhood Hits	580	Shared Neighborhood Hits	25
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

CCDC6_HUMAN
NC score	0.057814 (rank : 105)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	131	Target Neighborhood Hits	723	Shared Neighborhood Hits	31
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

HCLS1_MOUSE
NC score	0.057782 (rank : 106)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	131	Target Neighborhood Hits	329	Shared Neighborhood Hits	17
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

CEP57_HUMAN
NC score	0.057476 (rank : 107)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	131	Target Neighborhood Hits	576	Shared Neighborhood Hits	27
SwissProt Accessions	Q86XR8, Q14704, Q8IXP0, Q9BVF9	Gene names	CEP57, KIAA0092, TSP57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin) (FGF2-interacting protein).

TP53B_HUMAN
NC score	0.057374 (rank : 108)	θ value	1.06291 (rank : 59)
Query Neighborhood Hits	131	Target Neighborhood Hits	413	Shared Neighborhood Hits	26
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TUFT1_MOUSE
NC score	0.057318 (rank : 109)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	131	Target Neighborhood Hits	732	Shared Neighborhood Hits	31
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

SKI_HUMAN
NC score	0.057132 (rank : 110)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	131	Target Neighborhood Hits	423	Shared Neighborhood Hits	25
SwissProt Accessions	P12755, Q5SYT7	Gene names	SKI
Domain Architecture
Description	Ski oncogene (C-ski).

NOLC1_HUMAN
NC score	0.057063 (rank : 111)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	131	Target Neighborhood Hits	452	Shared Neighborhood Hits	36
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

TARSH_HUMAN
NC score	0.057022 (rank : 112)	θ value	0.21417 (rank : 32)
Query Neighborhood Hits	131	Target Neighborhood Hits	768	Shared Neighborhood Hits	39
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

SRRM1_HUMAN
NC score	0.056886 (rank : 113)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	131	Target Neighborhood Hits	690	Shared Neighborhood Hits	48
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

TSC1_HUMAN
NC score	0.056757 (rank : 114)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	131	Target Neighborhood Hits	765	Shared Neighborhood Hits	35
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

ABI3_HUMAN
NC score	0.056683 (rank : 115)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	131	Target Neighborhood Hits	227	Shared Neighborhood Hits	17
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

CCD21_MOUSE
NC score	0.056511 (rank : 116)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	131	Target Neighborhood Hits	1135	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

IFT74_HUMAN
NC score	0.056200 (rank : 117)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	131	Target Neighborhood Hits	949	Shared Neighborhood Hits	30
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

ABI1_HUMAN
NC score	0.056090 (rank : 118)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	131	Target Neighborhood Hits	257	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

ABI3_MOUSE
NC score	0.055914 (rank : 119)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	131	Target Neighborhood Hits	227	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

NCOA6_MOUSE
NC score	0.055892 (rank : 120)	θ value	0.813845 (rank : 47)
Query Neighborhood Hits	131	Target Neighborhood Hits	1076	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

MUC7_HUMAN
NC score	0.055879 (rank : 121)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	131	Target Neighborhood Hits	538	Shared Neighborhood Hits	39
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

BSN_MOUSE
NC score	0.055875 (rank : 122)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	131	Target Neighborhood Hits	2057	Shared Neighborhood Hits	72
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

NCF4_HUMAN
NC score	0.055875 (rank : 123)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	131	Target Neighborhood Hits	161	Shared Neighborhood Hits	6
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

ZN750_HUMAN
NC score	0.055856 (rank : 124)	θ value	0.0736092 (rank : 24)
Query Neighborhood Hits	131	Target Neighborhood Hits	183	Shared Neighborhood Hits	10
SwissProt Accessions	Q32MQ0, Q9H899	Gene names	ZNF750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

ABI2_MOUSE
NC score	0.055665 (rank : 125)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	131	Target Neighborhood Hits	266	Shared Neighborhood Hits	11
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

CUTL1_MOUSE
NC score	0.055664 (rank : 126)	θ value	2.36792 (rank : 71)
Query Neighborhood Hits	131	Target Neighborhood Hits	1620	Shared Neighborhood Hits	61
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

MDC1_HUMAN
NC score	0.055567 (rank : 127)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	131	Target Neighborhood Hits	1446	Shared Neighborhood Hits	62
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

PREX1_HUMAN
NC score	0.055306 (rank : 128)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	131	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

ABI1_MOUSE
NC score	0.055181 (rank : 129)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	131	Target Neighborhood Hits	246	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

TAXB1_HUMAN
NC score	0.055128 (rank : 130)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	131	Target Neighborhood Hits	829	Shared Neighborhood Hits	28
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

CP250_HUMAN
NC score	0.055110 (rank : 131)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	131	Target Neighborhood Hits	1805	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

BRE1B_HUMAN
NC score	0.054874 (rank : 132)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	131	Target Neighborhood Hits	1040	Shared Neighborhood Hits	37
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

RENT2_HUMAN
NC score	0.054805 (rank : 133)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	131	Target Neighborhood Hits	618	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

TRIPB_HUMAN
NC score	0.054485 (rank : 134)	θ value	0.813845 (rank : 50)
Query Neighborhood Hits	131	Target Neighborhood Hits	1587	Shared Neighborhood Hits	41
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

CT096_HUMAN
NC score	0.054286 (rank : 135)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	131	Target Neighborhood Hits	438	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NUD7, Q8N840, Q8NAX5	Gene names	C20orf96
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf96.

SDCG8_HUMAN
NC score	0.054226 (rank : 136)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	131	Target Neighborhood Hits	1002	Shared Neighborhood Hits	36
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

GNRP_HUMAN
NC score	0.054220 (rank : 137)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	131	Target Neighborhood Hits	239	Shared Neighborhood Hits	9
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

HIP1_HUMAN
NC score	0.053966 (rank : 138)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	131	Target Neighborhood Hits	1016	Shared Neighborhood Hits	33
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

NEB2_MOUSE
NC score	0.053922 (rank : 139)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	131	Target Neighborhood Hits	889	Shared Neighborhood Hits	37
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

MD1L1_MOUSE
NC score	0.053627 (rank : 140)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	131	Target Neighborhood Hits	1001	Shared Neighborhood Hits	32
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

STAM1_MOUSE
NC score	0.053480 (rank : 141)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	131	Target Neighborhood Hits	273	Shared Neighborhood Hits	11
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

WBP11_MOUSE
NC score	0.053411 (rank : 142)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	131	Target Neighborhood Hits	362	Shared Neighborhood Hits	24
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

LZTS1_HUMAN
NC score	0.053394 (rank : 143)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	131	Target Neighborhood Hits	532	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y250, Q9Y5V7, Q9Y5V8, Q9Y5V9, Q9Y5W0, Q9Y5W1, Q9Y5W2	Gene names	LZTS1, FEZ1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

SRRM2_HUMAN
NC score	0.053382 (rank : 144)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	131	Target Neighborhood Hits	1296	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

PITM2_HUMAN
NC score	0.053326 (rank : 145)	θ value	0.0961366 (rank : 26)
Query Neighborhood Hits	131	Target Neighborhood Hits	52	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BZ72, Q9P271	Gene names	PITPNM2, KIAA1457, NIR3
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 2 (Phosphatidylinositol transfer protein, membrane-associated 2) (Pyk2 N-terminal domain-interacting receptor 3) (NIR-3).

STAC3_MOUSE
NC score	0.053203 (rank : 146)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	131	Target Neighborhood Hits	232	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

GNRP_MOUSE
NC score	0.053134 (rank : 147)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	131	Target Neighborhood Hits	191	Shared Neighborhood Hits	8
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

NACAM_MOUSE
NC score	0.053027 (rank : 148)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	131	Target Neighborhood Hits	1866	Shared Neighborhood Hits	74
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

STAC3_HUMAN
NC score	0.052972 (rank : 149)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	131	Target Neighborhood Hits	228	Shared Neighborhood Hits	10
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

SKI_MOUSE
NC score	0.052945 (rank : 150)	θ value	1.38821 (rank : 62)
Query Neighborhood Hits	131	Target Neighborhood Hits	423	Shared Neighborhood Hits	23
SwissProt Accessions	Q60698, Q8VIL5	Gene names	Ski
Domain Architecture	No domain graphic available
Description	Ski oncogene (C-ski).

MLL2_HUMAN
NC score	0.052714 (rank : 151)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	131	Target Neighborhood Hits	1788	Shared Neighborhood Hits	71
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

FA62A_HUMAN
NC score	0.052667 (rank : 152)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	131	Target Neighborhood Hits	168	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

CCD27_HUMAN
NC score	0.052656 (rank : 153)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	131	Target Neighborhood Hits	594	Shared Neighborhood Hits	25
SwissProt Accessions	Q2M243, Q5TBV3, Q96M50	Gene names	CCDC27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

CCD41_HUMAN
NC score	0.052534 (rank : 154)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	131	Target Neighborhood Hits	1139	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

GOGA1_HUMAN
NC score	0.052482 (rank : 155)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	131	Target Neighborhood Hits	1222	Shared Neighborhood Hits	38
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

RIMB1_HUMAN
NC score	0.052470 (rank : 156)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	131	Target Neighborhood Hits	1479	Shared Neighborhood Hits	55
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

GRAP1_MOUSE
NC score	0.052390 (rank : 157)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	131	Target Neighborhood Hits	1234	Shared Neighborhood Hits	39
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

GRAP_MOUSE
NC score	0.052373 (rank : 158)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	131	Target Neighborhood Hits	309	Shared Neighborhood Hits	11
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

GRAP_HUMAN
NC score	0.052348 (rank : 159)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	131	Target Neighborhood Hits	307	Shared Neighborhood Hits	11
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

CNTRB_MOUSE
NC score	0.052249 (rank : 160)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	131	Target Neighborhood Hits	1029	Shared Neighborhood Hits	42
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

WBP11_HUMAN
NC score	0.052227 (rank : 161)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	131	Target Neighborhood Hits	354	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

CDC37_HUMAN
NC score	0.052144 (rank : 162)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	131	Target Neighborhood Hits	506	Shared Neighborhood Hits	18
SwissProt Accessions	Q16543	Gene names	CDC37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

FA62A_MOUSE
NC score	0.051932 (rank : 163)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	131	Target Neighborhood Hits	155	Shared Neighborhood Hits	6
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

NEST_HUMAN
NC score	0.051924 (rank : 164)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	131	Target Neighborhood Hits	1305	Shared Neighborhood Hits	49
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

CARD9_HUMAN
NC score	0.051914 (rank : 165)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	131	Target Neighborhood Hits	602	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H257, Q5SXM6, Q9H854	Gene names	CARD9
Domain Architecture
Description	Caspase recruitment domain-containing protein 9 (hCARD9).

STAM1_HUMAN
NC score	0.051886 (rank : 166)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	131	Target Neighborhood Hits	271	Shared Neighborhood Hits	11
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

RABE2_HUMAN
NC score	0.051789 (rank : 167)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	131	Target Neighborhood Hits	545	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H5N1	Gene names	RABEP2, RABPT5B
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

GOGA5_MOUSE
NC score	0.051769 (rank : 168)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	131	Target Neighborhood Hits	1434	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

RFIP4_HUMAN
NC score	0.051699 (rank : 169)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	131	Target Neighborhood Hits	785	Shared Neighborhood Hits	31
SwissProt Accessions	Q86YS3, Q8N829, Q8NDT7, Q969D8	Gene names	RAB11FIP4, KIAA1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

NCOA6_HUMAN
NC score	0.051685 (rank : 170)	θ value	3.0926 (rank : 85)
Query Neighborhood Hits	131	Target Neighborhood Hits	1202	Shared Neighborhood Hits	48
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

ECT2_MOUSE
NC score	0.051612 (rank : 171)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	131	Target Neighborhood Hits	98	Shared Neighborhood Hits	7
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

SAS6_MOUSE
NC score	0.051575 (rank : 172)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	131	Target Neighborhood Hits	931	Shared Neighborhood Hits	32
SwissProt Accessions	Q80UK7, Q9CYT4	Gene names	Sass6, Sas6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog.

GOGA1_MOUSE
NC score	0.051554 (rank : 173)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	131	Target Neighborhood Hits	994	Shared Neighborhood Hits	33
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

PKHG1_HUMAN
NC score	0.051497 (rank : 174)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	131	Target Neighborhood Hits	174	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

CCD13_HUMAN
NC score	0.051464 (rank : 175)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	131	Target Neighborhood Hits	721	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IYE1	Gene names	CCDC13
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 13.

NEMO_HUMAN
NC score	0.051419 (rank : 176)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	131	Target Neighborhood Hits	820	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

LZTS1_MOUSE
NC score	0.051389 (rank : 177)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	131	Target Neighborhood Hits	540	Shared Neighborhood Hits	25
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

K0555_HUMAN
NC score	0.051282 (rank : 178)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	131	Target Neighborhood Hits	880	Shared Neighborhood Hits	33
SwissProt Accessions	Q96AA8, O60302	Gene names	KIAA0555
Domain Architecture	No domain graphic available
Description	Protein KIAA0555.

IFT81_MOUSE
NC score	0.051245 (rank : 179)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	131	Target Neighborhood Hits	959	Shared Neighborhood Hits	31
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

SWP70_MOUSE
NC score	0.051202 (rank : 180)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	131	Target Neighborhood Hits	1097	Shared Neighborhood Hits	33
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

STAM2_MOUSE
NC score	0.051049 (rank : 181)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	131	Target Neighborhood Hits	285	Shared Neighborhood Hits	11
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

INVO_MOUSE
NC score	0.050985 (rank : 182)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	131	Target Neighborhood Hits	474	Shared Neighborhood Hits	33
SwissProt Accessions	P48997	Gene names	Ivl
Domain Architecture	No domain graphic available
Description	Involucrin.

IWS1_HUMAN
NC score	0.050888 (rank : 183)	θ value	0.0431538 (rank : 21)
Query Neighborhood Hits	131	Target Neighborhood Hits	1241	Shared Neighborhood Hits	41
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

NCF4_MOUSE
NC score	0.050879 (rank : 184)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	131	Target Neighborhood Hits	177	Shared Neighborhood Hits	6
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

TCRG1_MOUSE
NC score	0.050762 (rank : 185)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	131	Target Neighborhood Hits	947	Shared Neighborhood Hits	44
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

CCHCR_MOUSE
NC score	0.050696 (rank : 186)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	131	Target Neighborhood Hits	932	Shared Neighborhood Hits	33
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

ENAH_MOUSE
NC score	0.050573 (rank : 187)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	131	Target Neighborhood Hits	919	Shared Neighborhood Hits	47
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

OPTN_HUMAN
NC score	0.050500 (rank : 188)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	131	Target Neighborhood Hits	827	Shared Neighborhood Hits	31
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

RABE1_HUMAN
NC score	0.050446 (rank : 189)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	131	Target Neighborhood Hits	1104	Shared Neighborhood Hits	33
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

GAS8_HUMAN
NC score	0.050434 (rank : 190)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	131	Target Neighborhood Hits	819	Shared Neighborhood Hits	28
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

NAF1_HUMAN
NC score	0.050396 (rank : 191)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	131	Target Neighborhood Hits	937	Shared Neighborhood Hits	35
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

CUTL1_HUMAN
NC score	0.050384 (rank : 192)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	131	Target Neighborhood Hits	1574	Shared Neighborhood Hits	52
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

SMC2_HUMAN
NC score	0.050333 (rank : 193)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	131	Target Neighborhood Hits	1405	Shared Neighborhood Hits	41
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

CE152_HUMAN
NC score	0.050306 (rank : 194)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	131	Target Neighborhood Hits	976	Shared Neighborhood Hits	33
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

SRRM2_MOUSE
NC score	0.050280 (rank : 195)	θ value	1.38821 (rank : 63)
Query Neighborhood Hits	131	Target Neighborhood Hits	1470	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

K1543_MOUSE
NC score	0.050218 (rank : 196)	θ value	2.36792 (rank : 74)
Query Neighborhood Hits	131	Target Neighborhood Hits	497	Shared Neighborhood Hits	31
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

IFT74_MOUSE
NC score	0.050180 (rank : 197)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	131	Target Neighborhood Hits	939	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

CN145_HUMAN
NC score	0.050061 (rank : 198)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	131	Target Neighborhood Hits	1196	Shared Neighborhood Hits	34
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

CK5P2_HUMAN
NC score	0.050057 (rank : 199)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	131	Target Neighborhood Hits	1433	Shared Neighborhood Hits	43
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

ASPP1_HUMAN
NC score	0.050037 (rank : 200)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	131	Target Neighborhood Hits	956	Shared Neighborhood Hits	37
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

GOGA6_HUMAN
NC score	0.050034 (rank : 201)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	131	Target Neighborhood Hits	1007	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

EFS_HUMAN
NC score	0.050027 (rank : 202)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	131	Target Neighborhood Hits	348	Shared Neighborhood Hits	23
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

TRAIP_HUMAN
NC score	0.050015 (rank : 203)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	131	Target Neighborhood Hits	780	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

NUCB2_MOUSE
NC score	0.050014 (rank : 204)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	131	Target Neighborhood Hits	459	Shared Neighborhood Hits	23
SwissProt Accessions	P81117	Gene names	Nucb2, Nefa
Domain Architecture	No domain graphic available
Description	Nucleobindin-2 precursor (DNA-binding protein NEFA).

CI039_HUMAN
NC score	0.049578 (rank : 205)	θ value	5.27518 (rank : 104)
Query Neighborhood Hits	131	Target Neighborhood Hits	1171	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

K2027_HUMAN
NC score	0.047920 (rank : 206)	θ value	0.47712 (rank : 39)
Query Neighborhood Hits	131	Target Neighborhood Hits	194	Shared Neighborhood Hits	18
SwissProt Accessions	Q6ZVF9, Q8IVE4	Gene names	KIAA2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

SEPT9_HUMAN
NC score	0.047256 (rank : 207)	θ value	0.21417 (rank : 31)
Query Neighborhood Hits	131	Target Neighborhood Hits	706	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

TGON2_HUMAN
NC score	0.046674 (rank : 208)	θ value	0.279714 (rank : 36)
Query Neighborhood Hits	131	Target Neighborhood Hits	1037	Shared Neighborhood Hits	40
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

MACF4_HUMAN
NC score	0.046108 (rank : 209)	θ value	3.0926 (rank : 84)
Query Neighborhood Hits	131	Target Neighborhood Hits	1321	Shared Neighborhood Hits	42
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

DDEF1_MOUSE
NC score	0.045597 (rank : 210)	θ value	5.27518 (rank : 105)
Query Neighborhood Hits	131	Target Neighborhood Hits	592	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

NRIP1_MOUSE
NC score	0.045313 (rank : 211)	θ value	0.163984 (rank : 28)
Query Neighborhood Hits	131	Target Neighborhood Hits	110	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CBD1, Q8C3Y8, Q9Z2K2	Gene names	Nrip1
Domain Architecture	No domain graphic available
Description	Nuclear receptor-interacting protein 1 (Nuclear factor RIP140) (Receptor-interacting protein 140).

RAPH1_HUMAN
NC score	0.044178 (rank : 212)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	131	Target Neighborhood Hits	593	Shared Neighborhood Hits	43
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

KIFC3_HUMAN
NC score	0.043324 (rank : 213)	θ value	0.62314 (rank : 41)
Query Neighborhood Hits	131	Target Neighborhood Hits	619	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BVG8, O75299, Q8IUT3, Q96HW6	Gene names	KIFC3
Domain Architecture
Description	Kinesin-like protein KIFC3.

ICB1_MOUSE
NC score	0.043263 (rank : 214)	θ value	0.163984 (rank : 27)
Query Neighborhood Hits	131	Target Neighborhood Hits	69	Shared Neighborhood Hits	7
SwissProt Accessions	Q91YX0	Gene names	Icb1
Domain Architecture	No domain graphic available
Description	Induced by contact to basement membrane 1 protein homolog (ICB-1 protein).

TTF1_MOUSE
NC score	0.042831 (rank : 215)	θ value	0.62314 (rank : 44)
Query Neighborhood Hits	131	Target Neighborhood Hits	277	Shared Neighborhood Hits	16
SwissProt Accessions	Q62187, Q9JKK5	Gene names	Ttf1
Domain Architecture	No domain graphic available
Description	Transcription termination factor 1 (TTF-1) (TTF-I) (mTFF-I) (RNA polymerase I termination factor).

MAP9_HUMAN
NC score	0.042595 (rank : 216)	θ value	0.813845 (rank : 46)
Query Neighborhood Hits	131	Target Neighborhood Hits	518	Shared Neighborhood Hits	18
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

KIFC3_MOUSE
NC score	0.041814 (rank : 217)	θ value	2.36792 (rank : 75)
Query Neighborhood Hits	131	Target Neighborhood Hits	571	Shared Neighborhood Hits	25
SwissProt Accessions	O35231, Q91YQ2	Gene names	Kifc3
Domain Architecture
Description	Kinesin-like protein KIFC3.

PO121_HUMAN
NC score	0.041778 (rank : 218)	θ value	2.36792 (rank : 78)
Query Neighborhood Hits	131	Target Neighborhood Hits	344	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

ASXL1_MOUSE
NC score	0.041311 (rank : 219)	θ value	2.36792 (rank : 69)
Query Neighborhood Hits	131	Target Neighborhood Hits	182	Shared Neighborhood Hits	18
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

PI5PA_HUMAN
NC score	0.041299 (rank : 220)	θ value	0.279714 (rank : 35)
Query Neighborhood Hits	131	Target Neighborhood Hits	749	Shared Neighborhood Hits	35
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

BPA1_MOUSE
NC score	0.040942 (rank : 221)	θ value	3.0926 (rank : 82)
Query Neighborhood Hits	131	Target Neighborhood Hits	1477	Shared Neighborhood Hits	35
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

WBS14_HUMAN
NC score	0.040452 (rank : 222)	θ value	1.81305 (rank : 68)
Query Neighborhood Hits	131	Target Neighborhood Hits	273	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

RBBP6_HUMAN
NC score	0.040260 (rank : 223)	θ value	2.36792 (rank : 79)
Query Neighborhood Hits	131	Target Neighborhood Hits	1135	Shared Neighborhood Hits	45
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

ARI5B_HUMAN
NC score	0.039491 (rank : 224)	θ value	0.47712 (rank : 38)
Query Neighborhood Hits	131	Target Neighborhood Hits	328	Shared Neighborhood Hits	23
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

BPAEA_HUMAN
NC score	0.039432 (rank : 225)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	131	Target Neighborhood Hits	1369	Shared Neighborhood Hits	39
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BLNK_HUMAN
NC score	0.039357 (rank : 226)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	131	Target Neighborhood Hits	228	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WV28, O75498, O75499	Gene names	BLNK, BASH, SLP65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (SLP-65).

MACF1_HUMAN
NC score	0.038256 (rank : 227)	θ value	2.36792 (rank : 77)
Query Neighborhood Hits	131	Target Neighborhood Hits	1341	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

ERRFI_MOUSE
NC score	0.037028 (rank : 228)	θ value	2.36792 (rank : 72)
Query Neighborhood Hits	131	Target Neighborhood Hits	72	Shared Neighborhood Hits	8
SwissProt Accessions	Q99JZ7	Gene names	Errfi1, Mig6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein homolog) (Mig-6).

NFH_MOUSE
NC score	0.035984 (rank : 229)	θ value	0.62314 (rank : 42)
Query Neighborhood Hits	131	Target Neighborhood Hits	2247	Shared Neighborhood Hits	75
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

MAP4_HUMAN
NC score	0.035490 (rank : 230)	θ value	1.81305 (rank : 65)
Query Neighborhood Hits	131	Target Neighborhood Hits	428	Shared Neighborhood Hits	25
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

PWWP2_HUMAN
NC score	0.033994 (rank : 231)	θ value	3.0926 (rank : 87)
Query Neighborhood Hits	131	Target Neighborhood Hits	80	Shared Neighborhood Hits	7
SwissProt Accessions	Q6NUJ5, Q5SZI0, Q6ZQX5, Q96F43	Gene names	PWWP2
Domain Architecture	No domain graphic available
Description	PWWP domain-containing protein 2.

RUNX1_HUMAN
NC score	0.033186 (rank : 232)	θ value	0.813845 (rank : 48)
Query Neighborhood Hits	131	Target Neighborhood Hits	94	Shared Neighborhood Hits	8
SwissProt Accessions	Q01196, O60472, O60473, O76047, O76089, Q13081, Q13755, Q13756, Q13757, Q13758, Q13759, Q15341, Q15343, Q16122, Q16284, Q16285, Q16286, Q16346, Q16347, Q92479	Gene names	RUNX1, AML1, CBFA2
Domain Architecture
Description	Runt-related transcription factor 1 (Core-binding factor, alpha 2 subunit) (CBF-alpha 2) (Acute myeloid leukemia 1 protein) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEBP2-alpha B) (PEA2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit).

CCD25_HUMAN
NC score	0.032782 (rank : 233)	θ value	4.03905 (rank : 91)
Query Neighborhood Hits	131	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	Q86WR0, Q96SI2, Q9NV98	Gene names	CCDC25
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 25.

ROCK2_MOUSE
NC score	0.032367 (rank : 234)	θ value	3.0926 (rank : 88)
Query Neighborhood Hits	131	Target Neighborhood Hits	2072	Shared Neighborhood Hits	47
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

CCD25_MOUSE
NC score	0.031911 (rank : 235)	θ value	4.03905 (rank : 92)
Query Neighborhood Hits	131	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q78PG9, Q9CSQ8, Q9CUF8	Gene names	Ccdc25
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 25.

PITM3_MOUSE
NC score	0.031886 (rank : 236)	θ value	5.27518 (rank : 109)
Query Neighborhood Hits	131	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	Q3UHE1, Q3UH22, Q5RIT9	Gene names	Pitpnm3, Nir1
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 3 (Phosphatidylinositol transfer protein, membrane-associated 3) (Pyk2 N-terminal domain-interacting receptor 1) (NIR-1).

PITM2_MOUSE
NC score	0.029953 (rank : 237)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	131	Target Neighborhood Hits	46	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZPQ6, Q9R1P5	Gene names	Pitpnm2, Kiaa1457, Nir3
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 2 (Phosphatidylinositol transfer protein, membrane-associated 2) (Pyk2 N-terminal domain-interacting receptor 3) (NIR-3) (Drosophila retinal degeneration B homolog 2) (RdgB2).

PITM3_HUMAN
NC score	0.029698 (rank : 238)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	131	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BZ71, Q59GH9, Q9NPQ4	Gene names	PITPNM3, NIR1
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 3 (Phosphatidylinositol transfer protein, membrane-associated 3) (Pyk2 N-terminal domain-interacting receptor 1) (NIR-1).

SPY2_MOUSE
NC score	0.029428 (rank : 239)	θ value	1.06291 (rank : 56)
Query Neighborhood Hits	131	Target Neighborhood Hits	71	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QXV8, Q9WUQ9	Gene names	Spry2
Domain Architecture
Description	Sprouty homolog 2 (Spry-2).

AFF2_MOUSE
NC score	0.028777 (rank : 240)	θ value	4.03905 (rank : 90)
Query Neighborhood Hits	131	Target Neighborhood Hits	225	Shared Neighborhood Hits	24
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

NCOR1_HUMAN
NC score	0.028416 (rank : 241)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	131	Target Neighborhood Hits	577	Shared Neighborhood Hits	36
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

ENKUR_HUMAN
NC score	0.028323 (rank : 242)	θ value	4.03905 (rank : 94)
Query Neighborhood Hits	131	Target Neighborhood Hits	64	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TC29	Gene names	C10orf63
Domain Architecture	No domain graphic available
Description	Enkurin.

ROCK2_HUMAN
NC score	0.027861 (rank : 243)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	131	Target Neighborhood Hits	2073	Shared Neighborhood Hits	45
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

SAPS1_HUMAN
NC score	0.026072 (rank : 244)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	131	Target Neighborhood Hits	704	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

K1802_MOUSE
NC score	0.026061 (rank : 245)	θ value	4.03905 (rank : 96)
Query Neighborhood Hits	131	Target Neighborhood Hits	1596	Shared Neighborhood Hits	48
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

CQ028_HUMAN
NC score	0.026028 (rank : 246)	θ value	1.81305 (rank : 64)
Query Neighborhood Hits	131	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IV36, Q8N5L6, Q8TE83, Q9NT34	Gene names	C17orf28, DMC1
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf28 (Down-regulated in multiple cancers- 1).

PRGC2_HUMAN
NC score	0.025523 (rank : 247)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	131	Target Neighborhood Hits	272	Shared Neighborhood Hits	21
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

MA1B1_HUMAN
NC score	0.024681 (rank : 248)	θ value	4.03905 (rank : 97)
Query Neighborhood Hits	131	Target Neighborhood Hits	125	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UKM7, Q5VSG3, Q9BRS9, Q9Y5K7	Gene names	MAN1B1
Domain Architecture
Description	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (Mannosidase alpha class 1B member 1) (Man9GlcNAc2-specific-processing alpha-mannosidase).

SPY2_HUMAN
NC score	0.023029 (rank : 249)	θ value	4.03905 (rank : 101)
Query Neighborhood Hits	131	Target Neighborhood Hits	66	Shared Neighborhood Hits	3
SwissProt Accessions	O43597, Q5T6Z7	Gene names	SPRY2
Domain Architecture
Description	Sprouty homolog 2 (Spry-2).

NSD1_HUMAN
NC score	0.022197 (rank : 250)	θ value	3.0926 (rank : 86)
Query Neighborhood Hits	131	Target Neighborhood Hits	427	Shared Neighborhood Hits	26
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

SEPT9_MOUSE
NC score	0.021893 (rank : 251)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	131	Target Neighborhood Hits	238	Shared Neighborhood Hits	16
SwissProt Accessions	Q80UG5, Q3URP2, Q80TM7, Q9QYX9	Gene names	Sept9, Kiaa0991, Sint1
Domain Architecture	No domain graphic available
Description	Septin-9 (SL3-3 integration site 1 protein).

LARP1_HUMAN
NC score	0.021776 (rank : 252)	θ value	8.99809 (rank : 127)
Query Neighborhood Hits	131	Target Neighborhood Hits	242	Shared Neighborhood Hits	15
SwissProt Accessions	Q6PKG0, O94836, Q8N4M2, Q8NB73, Q9UFD7	Gene names	LARP1, KIAA0731, LARP
Domain Architecture	No domain graphic available
Description	La-related protein 1 (La ribonucleoprotein domain family member 1).

CABYR_HUMAN
NC score	0.021246 (rank : 253)	θ value	5.27518 (rank : 103)
Query Neighborhood Hits	131	Target Neighborhood Hits	87	Shared Neighborhood Hits	11
SwissProt Accessions	O75952, Q8WXW5, Q9HAY3, Q9HAY4, Q9HAY5, Q9HCY9	Gene names	CABYR, CBP86, FSP2
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86) (Fibrousheathin-2) (FSP-2).

RFX1_MOUSE
NC score	0.020324 (rank : 254)	θ value	4.03905 (rank : 100)
Query Neighborhood Hits	131	Target Neighborhood Hits	181	Shared Neighborhood Hits	25
SwissProt Accessions	P48377	Gene names	Rfx1
Domain Architecture
Description	DNA-binding protein RFX1.

JHD3C_MOUSE
NC score	0.019198 (rank : 255)	θ value	0.62314 (rank : 40)
Query Neighborhood Hits	131	Target Neighborhood Hits	84	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VCD7, Q3UNP7, Q69ZZ5, Q8BUY6, Q8BWA1	Gene names	Jmjd2c, Jhdm3c, Kiaa0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C).

FA5_HUMAN
NC score	0.019087 (rank : 256)	θ value	2.36792 (rank : 73)
Query Neighborhood Hits	131	Target Neighborhood Hits	172	Shared Neighborhood Hits	12
SwissProt Accessions	P12259, Q14285, Q6UPU6	Gene names	F5
Domain Architecture
Description	Coagulation factor V precursor (Activated protein C cofactor) [Contains: Coagulation factor V heavy chain; Coagulation factor V light chain].

RUNX1_MOUSE
NC score	0.018954 (rank : 257)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	131	Target Neighborhood Hits	93	Shared Neighborhood Hits	7
SwissProt Accessions	Q03347, O08598, Q62049, Q9ESB9, Q9ET65	Gene names	Runx1, Aml1, Cbfa2, Pebp2ab
Domain Architecture
Description	Runt-related transcription factor 1 (Core-binding factor, alpha 2 subunit) (CBF-alpha 2) (Acute myeloid leukemia 1 protein) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEBP2-alpha B) (PEA2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit).

TIP60_MOUSE
NC score	0.018133 (rank : 258)	θ value	4.03905 (rank : 102)
Query Neighborhood Hits	131	Target Neighborhood Hits	95	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CHK4, Q8CGZ3, Q8CGZ4, Q8VIH0	Gene names	Htatip, Tip60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60).

M4K4_MOUSE
NC score	0.017366 (rank : 259)	θ value	3.0926 (rank : 83)
Query Neighborhood Hits	131	Target Neighborhood Hits	1560	Shared Neighborhood Hits	38
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

TIP60_HUMAN
NC score	0.016689 (rank : 260)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	131	Target Neighborhood Hits	90	Shared Neighborhood Hits	11
SwissProt Accessions	Q92993, O95624, Q13430, Q6GSE8, Q9BWK7	Gene names	HTATIP, TIP60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60) (HIV-1 Tat interactive protein) (cPLA(2)-interacting protein).

TFE3_HUMAN
NC score	0.016673 (rank : 261)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	131	Target Neighborhood Hits	190	Shared Neighborhood Hits	10
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

CSPG3_HUMAN
NC score	0.016650 (rank : 262)	θ value	1.38821 (rank : 61)
Query Neighborhood Hits	131	Target Neighborhood Hits	676	Shared Neighborhood Hits	17
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

STAR8_HUMAN
NC score	0.015712 (rank : 263)	θ value	2.36792 (rank : 80)
Query Neighborhood Hits	131	Target Neighborhood Hits	216	Shared Neighborhood Hits	14
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

LATS1_HUMAN
NC score	0.014574 (rank : 264)	θ value	0.0961366 (rank : 25)
Query Neighborhood Hits	131	Target Neighborhood Hits	1057	Shared Neighborhood Hits	30
SwissProt Accessions	O95835, Q6PKD0	Gene names	LATS1, WARTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts).

RC3H1_HUMAN
NC score	0.014494 (rank : 265)	θ value	4.03905 (rank : 99)
Query Neighborhood Hits	131	Target Neighborhood Hits	433	Shared Neighborhood Hits	14
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

ABL1_MOUSE
NC score	0.014123 (rank : 266)	θ value	3.0926 (rank : 81)
Query Neighborhood Hits	131	Target Neighborhood Hits	1178	Shared Neighborhood Hits	38
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

MYPN_MOUSE
NC score	0.013861 (rank : 267)	θ value	1.06291 (rank : 54)
Query Neighborhood Hits	131	Target Neighborhood Hits	421	Shared Neighborhood Hits	13
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

TOPB1_MOUSE
NC score	0.013445 (rank : 268)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	131	Target Neighborhood Hits	89	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZQF0, Q6P6P0, Q80Y33, Q8BUI0, Q8BUK1, Q8R348, Q91VX3, Q922X8	Gene names	Topbp1, Kiaa0259
Domain Architecture	No domain graphic available
Description	DNA topoisomerase II-binding protein 1 (DNA topoisomerase IIbeta- binding protein 1) (TopBP1).

HEM1_HUMAN
NC score	0.012221 (rank : 269)	θ value	4.03905 (rank : 95)
Query Neighborhood Hits	131	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	P13196	Gene names	ALAS1, ALASH
Domain Architecture
Description	5-aminolevulinate synthase, nonspecific, mitochondrial precursor (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta-aminolevulinate synthase) (Delta-ALA synthetase) (ALAS-H).

ABL1_HUMAN
NC score	0.011941 (rank : 270)	θ value	1.06291 (rank : 51)
Query Neighborhood Hits	131	Target Neighborhood Hits	1220	Shared Neighborhood Hits	31
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

CD2L7_HUMAN
NC score	0.011215 (rank : 271)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	131	Target Neighborhood Hits	1275	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

LPXN_MOUSE
NC score	0.010107 (rank : 272)	θ value	2.36792 (rank : 76)
Query Neighborhood Hits	131	Target Neighborhood Hits	227	Shared Neighborhood Hits	8
SwissProt Accessions	Q99N69	Gene names	Lpxn
Domain Architecture	No domain graphic available
Description	Leupaxin.

2A5D_HUMAN
NC score	0.009461 (rank : 273)	θ value	6.88961 (rank : 113)
Query Neighborhood Hits	131	Target Neighborhood Hits	59	Shared Neighborhood Hits	6
SwissProt Accessions	Q14738, O00494, O00696, Q15171	Gene names	PPP2R5D
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PP2A, B subunit, B' delta isoform) (PP2A, B subunit, B56 delta isoform) (PP2A, B subunit, PR61 delta isoform) (PP2A, B subunit, R5 delta isoform).

PDLI7_HUMAN
NC score	0.009415 (rank : 274)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	131	Target Neighborhood Hits	547	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

MAST4_HUMAN
NC score	0.008929 (rank : 275)	θ value	4.03905 (rank : 98)
Query Neighborhood Hits	131	Target Neighborhood Hits	1804	Shared Neighborhood Hits	42
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

NFAC3_HUMAN
NC score	0.008108 (rank : 276)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	131	Target Neighborhood Hits	102	Shared Neighborhood Hits	4
SwissProt Accessions	Q12968, O75211, Q14516, Q99840, Q99841, Q99842	Gene names	NFATC3, NFAT4
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx).

ICK_HUMAN
NC score	0.007653 (rank : 277)	θ value	0.813845 (rank : 45)
Query Neighborhood Hits	131	Target Neighborhood Hits	867	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UPZ9, O75985, Q5THL2, Q8IYH8, Q9BX17, Q9NYX3	Gene names	ICK, KIAA0936
Domain Architecture
Description	Serine/threonine-protein kinase ICK (EC 2.7.11.22) (Intestinal cell kinase) (hICK) (MAK-related kinase) (MRK) (Laryngeal cancer kinase 2) (LCK2).

LTB1L_HUMAN
NC score	0.000973 (rank : 278)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	131	Target Neighborhood Hits	553	Shared Neighborhood Hits	9
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).