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Network neighborhood for query Sequence : REV1_MOUSE

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REV1_MOUSE
SwissProt Accessions	Q920Q2, Q9QXV2	Gene names	Rev1l, Rev1
Domain Architecture	No domain graphic available
Description	DNA repair protein REV1 (EC 2.7.7.-) (Rev1-like terminal deoxycytidyl transferase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

REV1_HUMAN
θ value	0 (rank : 1)	NC score	0.980203 (rank : 2)
Query Neighborhood Hits	67	Target Neighborhood Hits	56	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UBZ9, O95941, Q9C0J4, Q9NUP2	Gene names	REV1L, REV1
Domain Architecture	No domain graphic available
Description	DNA repair protein REV1 (EC 2.7.7.-) (Rev1-like terminal deoxycytidyl transferase) (Alpha integrin-binding protein 80) (AIBP80).

REV1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	67	Target Neighborhood Hits	67	Shared Neighborhood Hits	67
SwissProt Accessions	Q920Q2, Q9QXV2	Gene names	Rev1l, Rev1
Domain Architecture	No domain graphic available
Description	DNA repair protein REV1 (EC 2.7.7.-) (Rev1-like terminal deoxycytidyl transferase).

POLK_MOUSE
θ value	1.5773e-20 (rank : 3)	NC score	0.579750 (rank : 3)
Query Neighborhood Hits	67	Target Neighborhood Hits	66	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QUG2, Q7TPY7	Gene names	Polk, Dinb1
Domain Architecture	No domain graphic available
Description	DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP).

POLI_HUMAN
θ value	9.56915e-18 (rank : 4)	NC score	0.571333 (rank : 4)
Query Neighborhood Hits	67	Target Neighborhood Hits	28	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UNA4, Q8N590, Q9H0S1, Q9NYH6	Gene names	POLI, RAD30B
Domain Architecture	No domain graphic available
Description	DNA polymerase iota (EC 2.7.7.7) (RAD30 homolog B) (Eta2).

POLI_MOUSE
θ value	5.25075e-16 (rank : 5)	NC score	0.565033 (rank : 5)
Query Neighborhood Hits	67	Target Neighborhood Hits	27	Shared Neighborhood Hits	11
SwissProt Accessions	Q6R3M4, Q641P1, Q6R3M3, Q9R1A6	Gene names	Poli, Rad30b
Domain Architecture	No domain graphic available
Description	DNA polymerase iota (EC 2.7.7.7) (Rad30 homolog B).

POLK_HUMAN
θ value	1.52774e-15 (rank : 6)	NC score	0.558697 (rank : 6)
Query Neighborhood Hits	67	Target Neighborhood Hits	64	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UBT6, Q86VJ8, Q8IZY0, Q8IZY1, Q8NB30, Q96L01, Q96Q86, Q96Q87, Q9UHC5	Gene names	POLK, DINB1
Domain Architecture	No domain graphic available
Description	DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP).

POLH_MOUSE
θ value	1.9326e-10 (rank : 7)	NC score	0.481926 (rank : 7)
Query Neighborhood Hits	67	Target Neighborhood Hits	29	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JJN0, Q9JJJ2	Gene names	Polh, Rad30a, Xpv
Domain Architecture	No domain graphic available
Description	DNA polymerase eta (EC 2.7.7.7) (RAD30 homolog A) (Xeroderma pigmentosum variant type protein homolog).

POLH_HUMAN
θ value	2.79066e-09 (rank : 8)	NC score	0.468484 (rank : 8)
Query Neighborhood Hits	67	Target Neighborhood Hits	44	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y253, Q7L8E3, Q96BC4, Q9BX13	Gene names	POLH, RAD30, RAD30A, XPV
Domain Architecture	No domain graphic available
Description	DNA polymerase eta (EC 2.7.7.7) (RAD30 homolog A) (Xeroderma pigmentosum variant type protein).

XRCC1_HUMAN
θ value	0.000461057 (rank : 9)	NC score	0.131154 (rank : 9)
Query Neighborhood Hits	67	Target Neighborhood Hits	131	Shared Neighborhood Hits	5
SwissProt Accessions	P18887, Q9HCB1	Gene names	XRCC1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

TOPB1_HUMAN
θ value	0.00175202 (rank : 10)	NC score	0.130748 (rank : 10)
Query Neighborhood Hits	67	Target Neighborhood Hits	82	Shared Neighborhood Hits	6
SwissProt Accessions	Q92547, Q7LGC1, Q9UEB9	Gene names	TOPBP1, KIAA0259
Domain Architecture	No domain graphic available
Description	DNA topoisomerase 2-binding protein 1 (DNA topoisomerase II-binding protein 1) (DNA topoisomerase IIbeta-binding protein 1) (TopBP1).

MAST4_HUMAN
θ value	0.00390308 (rank : 11)	NC score	0.017403 (rank : 45)
Query Neighborhood Hits	67	Target Neighborhood Hits	1804	Shared Neighborhood Hits	31
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

HUWE1_MOUSE
θ value	0.0193708 (rank : 12)	NC score	0.065331 (rank : 13)
Query Neighborhood Hits	67	Target Neighborhood Hits	406	Shared Neighborhood Hits	17
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

HUWE1_HUMAN
θ value	0.0330416 (rank : 13)	NC score	0.062091 (rank : 14)
Query Neighborhood Hits	67	Target Neighborhood Hits	443	Shared Neighborhood Hits	14
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

XRCC1_MOUSE
θ value	0.0330416 (rank : 14)	NC score	0.111396 (rank : 11)
Query Neighborhood Hits	67	Target Neighborhood Hits	242	Shared Neighborhood Hits	8
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

TRRAP_HUMAN
θ value	0.0736092 (rank : 15)	NC score	0.047772 (rank : 15)
Query Neighborhood Hits	67	Target Neighborhood Hits	117	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y4A5, O75218, Q9Y631, Q9Y6H4	Gene names	TRRAP, PAF400
Domain Architecture
Description	Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog).

MUC1_HUMAN
θ value	0.163984 (rank : 16)	NC score	0.029148 (rank : 25)
Query Neighborhood Hits	67	Target Neighborhood Hits	975	Shared Neighborhood Hits	24
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

ADDA_MOUSE
θ value	0.365318 (rank : 17)	NC score	0.043847 (rank : 17)
Query Neighborhood Hits	67	Target Neighborhood Hits	198	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QYC0, Q9JLE3	Gene names	Add1
Domain Architecture
Description	Alpha-adducin (Erythrocyte adducin subunit alpha).

TOPB1_MOUSE
θ value	0.365318 (rank : 18)	NC score	0.096992 (rank : 12)
Query Neighborhood Hits	67	Target Neighborhood Hits	89	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZQF0, Q6P6P0, Q80Y33, Q8BUI0, Q8BUK1, Q8R348, Q91VX3, Q922X8	Gene names	Topbp1, Kiaa0259
Domain Architecture	No domain graphic available
Description	DNA topoisomerase II-binding protein 1 (DNA topoisomerase IIbeta- binding protein 1) (TopBP1).

BRSK2_HUMAN
θ value	0.62314 (rank : 19)	NC score	0.006621 (rank : 66)
Query Neighborhood Hits	67	Target Neighborhood Hits	897	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IWQ3, O60843, O95099, Q5J5B4, Q8TB60	Gene names	BRSK2, C11orf7, PEN11B, STK29
Domain Architecture
Description	BR serine/threonine-protein kinase 2 (EC 2.7.11.1) (Serine/threonine- protein kinase 29) (SAD1B).

TACC2_HUMAN
θ value	0.62314 (rank : 20)	NC score	0.019454 (rank : 39)
Query Neighborhood Hits	67	Target Neighborhood Hits	856	Shared Neighborhood Hits	10
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

CMTA2_MOUSE
θ value	0.813845 (rank : 21)	NC score	0.030975 (rank : 24)
Query Neighborhood Hits	67	Target Neighborhood Hits	216	Shared Neighborhood Hits	7
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

MAGC1_HUMAN
θ value	0.813845 (rank : 22)	NC score	0.020667 (rank : 38)
Query Neighborhood Hits	67	Target Neighborhood Hits	431	Shared Neighborhood Hits	17
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

OXR1_MOUSE
θ value	1.06291 (rank : 23)	NC score	0.027557 (rank : 29)
Query Neighborhood Hits	67	Target Neighborhood Hits	516	Shared Neighborhood Hits	12
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

ZYX_MOUSE
θ value	1.06291 (rank : 24)	NC score	0.021979 (rank : 36)
Query Neighborhood Hits	67	Target Neighborhood Hits	347	Shared Neighborhood Hits	12
SwissProt Accessions	Q62523, P70461	Gene names	Zyx
Domain Architecture
Description	Zyxin.

ACK1_HUMAN
θ value	1.38821 (rank : 25)	NC score	0.007982 (rank : 64)
Query Neighborhood Hits	67	Target Neighborhood Hits	1140	Shared Neighborhood Hits	17
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

ADDA_HUMAN
θ value	1.38821 (rank : 26)	NC score	0.035615 (rank : 20)
Query Neighborhood Hits	67	Target Neighborhood Hits	108	Shared Neighborhood Hits	5
SwissProt Accessions	P35611, Q13734, Q14729, Q16156, Q9UJB6	Gene names	ADD1, ADDA
Domain Architecture
Description	Alpha-adducin (Erythrocyte adducin subunit alpha).

BRD4_HUMAN
θ value	1.38821 (rank : 27)	NC score	0.027822 (rank : 28)
Query Neighborhood Hits	67	Target Neighborhood Hits	851	Shared Neighborhood Hits	18
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

CSKI1_MOUSE
θ value	1.38821 (rank : 28)	NC score	0.015728 (rank : 51)
Query Neighborhood Hits	67	Target Neighborhood Hits	1031	Shared Neighborhood Hits	22
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

EP300_HUMAN
θ value	1.38821 (rank : 29)	NC score	0.026242 (rank : 31)
Query Neighborhood Hits	67	Target Neighborhood Hits	821	Shared Neighborhood Hits	19
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

RUSC2_MOUSE
θ value	1.38821 (rank : 30)	NC score	0.029095 (rank : 26)
Query Neighborhood Hits	67	Target Neighborhood Hits	305	Shared Neighborhood Hits	10
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

ACK1_MOUSE
θ value	1.81305 (rank : 31)	NC score	0.008080 (rank : 63)
Query Neighborhood Hits	67	Target Neighborhood Hits	1080	Shared Neighborhood Hits	15
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

ANR38_MOUSE
θ value	1.81305 (rank : 32)	NC score	0.016626 (rank : 49)
Query Neighborhood Hits	67	Target Neighborhood Hits	512	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

B3A3_HUMAN
θ value	1.81305 (rank : 33)	NC score	0.014048 (rank : 55)
Query Neighborhood Hits	67	Target Neighborhood Hits	119	Shared Neighborhood Hits	6
SwissProt Accessions	P48751	Gene names	SLC4A3, AE3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3) (Cardiac/brain band 3-like protein) (CAE3/BAE3).

CU059_HUMAN
θ value	1.81305 (rank : 34)	NC score	0.047079 (rank : 16)
Query Neighborhood Hits	67	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	P57076	Gene names	C21orf59, C21orf48
Domain Architecture	No domain graphic available
Description	Protein C21orf59.

K0329_HUMAN
θ value	1.81305 (rank : 35)	NC score	0.033623 (rank : 22)
Query Neighborhood Hits	67	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	O15040, Q9UEG6	Gene names	KIAA0329, KIAA0297
Domain Architecture
Description	Protein KIAA0329/KIAA0297.

NU133_MOUSE
θ value	1.81305 (rank : 36)	NC score	0.034797 (rank : 21)
Query Neighborhood Hits	67	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R0G9	Gene names	Nup133
Domain Architecture
Description	Nuclear pore complex protein Nup133 (Nucleoporin Nup133) (133 kDa nucleoporin).

AP180_HUMAN
θ value	2.36792 (rank : 37)	NC score	0.028521 (rank : 27)
Query Neighborhood Hits	67	Target Neighborhood Hits	183	Shared Neighborhood Hits	11
SwissProt Accessions	O60641, Q5JX13, Q68DL9, Q6P9D3, Q9NTY7	Gene names	SNAP91, KIAA0656
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein).

CI090_HUMAN
θ value	2.36792 (rank : 38)	NC score	0.043330 (rank : 19)
Query Neighborhood Hits	67	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q69YI7, Q8WU12	Gene names	C9orf90
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf90.

CI090_MOUSE
θ value	2.36792 (rank : 39)	NC score	0.043426 (rank : 18)
Query Neighborhood Hits	67	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PFD7	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf90 homolog.

K1802_MOUSE
θ value	2.36792 (rank : 40)	NC score	0.018161 (rank : 43)
Query Neighborhood Hits	67	Target Neighborhood Hits	1596	Shared Neighborhood Hits	28
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

LYRIC_MOUSE
θ value	2.36792 (rank : 41)	NC score	0.026528 (rank : 30)
Query Neighborhood Hits	67	Target Neighborhood Hits	126	Shared Neighborhood Hits	4
SwissProt Accessions	Q80WJ7, Q3U9F8, Q3UAQ8, Q8BN67, Q8CBT9, Q8CDL0, Q8CGI7, Q9D052	Gene names	Mtdh, Lyric
Domain Architecture	No domain graphic available
Description	Protein LYRIC (Lysine-rich CEACAM1 co-isolated protein) (3D3/LYRIC) (Metastasis adhesion protein) (Metadherin).

PHLB1_HUMAN
θ value	2.36792 (rank : 42)	NC score	0.020886 (rank : 37)
Query Neighborhood Hits	67	Target Neighborhood Hits	1038	Shared Neighborhood Hits	22
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

ECHA_HUMAN
θ value	3.0926 (rank : 43)	NC score	0.018903 (rank : 42)
Query Neighborhood Hits	67	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	P40939, Q16679, Q96GT7	Gene names	HADHA, HADH
Domain Architecture
Description	Trifunctional enzyme subunit alpha, mitochondrial precursor (TP-alpha) (78 kDa gastrin-binding protein) [Includes: Long-chain enoyl-CoA hydratase (EC 4.2.1.17); Long chain 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.211)].

TAB2_MOUSE
θ value	3.0926 (rank : 44)	NC score	0.019304 (rank : 40)
Query Neighborhood Hits	67	Target Neighborhood Hits	245	Shared Neighborhood Hits	5
SwissProt Accessions	Q99K90, Q3UGP1, Q8BTP4, Q8CHD3, Q99KP4	Gene names	Map3k7ip2, Kiaa0733, Tab2
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 2 (TAK1-binding protein 2) (TAB2).

BRD4_MOUSE
θ value	4.03905 (rank : 45)	NC score	0.024289 (rank : 34)
Query Neighborhood Hits	67	Target Neighborhood Hits	845	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

CE005_MOUSE
θ value	4.03905 (rank : 46)	NC score	0.015328 (rank : 53)
Query Neighborhood Hits	67	Target Neighborhood Hits	238	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

GSCR1_HUMAN
θ value	4.03905 (rank : 47)	NC score	0.032676 (rank : 23)
Query Neighborhood Hits	67	Target Neighborhood Hits	674	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

HCFC2_HUMAN
θ value	4.03905 (rank : 48)	NC score	0.013388 (rank : 56)
Query Neighborhood Hits	67	Target Neighborhood Hits	154	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5Z7	Gene names	HCFC2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

HDAC9_MOUSE
θ value	4.03905 (rank : 49)	NC score	0.016793 (rank : 48)
Query Neighborhood Hits	67	Target Neighborhood Hits	186	Shared Neighborhood Hits	5
SwissProt Accessions	Q99N13, Q9EPT2	Gene names	Hdac9, Hdac7b, Hdrp, Mitr
Domain Architecture	No domain graphic available
Description	Histone deacetylase 9 (HD9) (HD7B) (Histone deacetylase-related protein) (MEF2-interacting transcription repressor MITR).

PHLPP_MOUSE
θ value	4.03905 (rank : 50)	NC score	0.006818 (rank : 65)
Query Neighborhood Hits	67	Target Neighborhood Hits	394	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CHE4, Q6PCN0, Q8QZU8, Q8R5E5, Q99KL6	Gene names	Phlpp, Kiaa0606, Plekhe1, Scop
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein).

BCOR_HUMAN
θ value	5.27518 (rank : 51)	NC score	0.012135 (rank : 59)
Query Neighborhood Hits	67	Target Neighborhood Hits	609	Shared Neighborhood Hits	14
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

CN103_HUMAN
θ value	5.27518 (rank : 52)	NC score	0.017664 (rank : 44)
Query Neighborhood Hits	67	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q96BY7, Q6ZRE7, Q9NW80	Gene names	C14orf103
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf103.

CT160_HUMAN
θ value	5.27518 (rank : 53)	NC score	0.019184 (rank : 41)
Query Neighborhood Hits	67	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NUG4, Q5JYR9, Q8N5F1, Q8N6G8, Q96MD5	Gene names	C20orf160
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf160.

KIRR3_MOUSE
θ value	5.27518 (rank : 54)	NC score	0.010149 (rank : 61)
Query Neighborhood Hits	67	Target Neighborhood Hits	292	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BR86, Q6P555, Q810H3, Q8BGQ5, Q8BRS8	Gene names	Kirrel3, Kiaa1867
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3).

NFRKB_HUMAN
θ value	5.27518 (rank : 55)	NC score	0.023569 (rank : 35)
Query Neighborhood Hits	67	Target Neighborhood Hits	211	Shared Neighborhood Hits	11
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

PDLI5_HUMAN
θ value	5.27518 (rank : 56)	NC score	0.010516 (rank : 60)
Query Neighborhood Hits	67	Target Neighborhood Hits	322	Shared Neighborhood Hits	8
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

SDCG1_HUMAN
θ value	5.27518 (rank : 57)	NC score	0.017327 (rank : 46)
Query Neighborhood Hits	67	Target Neighborhood Hits	190	Shared Neighborhood Hits	4
SwissProt Accessions	O60524, Q8WW70, Q9NWG1	Gene names	SDCCAG1
Domain Architecture
Description	Serologically defined colon cancer antigen 1 (Antigen NY-CO-1).

ZN318_HUMAN
θ value	5.27518 (rank : 58)	NC score	0.016016 (rank : 50)
Query Neighborhood Hits	67	Target Neighborhood Hits	497	Shared Neighborhood Hits	6
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

CE005_HUMAN
θ value	6.88961 (rank : 59)	NC score	0.013034 (rank : 57)
Query Neighborhood Hits	67	Target Neighborhood Hits	213	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

LIMA1_HUMAN
θ value	6.88961 (rank : 60)	NC score	0.012162 (rank : 58)
Query Neighborhood Hits	67	Target Neighborhood Hits	309	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UHB6, Q2TAN7, Q9BVF2, Q9H8J1, Q9HBN5, Q9NX96, Q9NXC3, Q9NXU6, Q9P0H8, Q9UHB5	Gene names	LIMA1, EPLIN, SREBP3
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm).

MLL3_MOUSE
θ value	6.88961 (rank : 61)	NC score	0.015156 (rank : 54)
Query Neighborhood Hits	67	Target Neighborhood Hits	1399	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

PLCD1_MOUSE
θ value	6.88961 (rank : 62)	NC score	0.009103 (rank : 62)
Query Neighborhood Hits	67	Target Neighborhood Hits	106	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R3B1	Gene names	Plcd1, Plcd
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

RIN3_HUMAN
θ value	6.88961 (rank : 63)	NC score	0.016895 (rank : 47)
Query Neighborhood Hits	67	Target Neighborhood Hits	227	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

SN1L1_HUMAN
θ value	6.88961 (rank : 64)	NC score	0.003891 (rank : 67)
Query Neighborhood Hits	67	Target Neighborhood Hits	911	Shared Neighborhood Hits	8
SwissProt Accessions	P57059, Q5R2V5, Q86YJ2	Gene names	SNF1LK
Domain Architecture
Description	Serine/threonine-protein kinase SNF1-like kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase SNF1LK).

TAF4_HUMAN
θ value	6.88961 (rank : 65)	NC score	0.024595 (rank : 32)
Query Neighborhood Hits	67	Target Neighborhood Hits	687	Shared Neighborhood Hits	16
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

BPTF_HUMAN
θ value	8.99809 (rank : 66)	NC score	0.015491 (rank : 52)
Query Neighborhood Hits	67	Target Neighborhood Hits	786	Shared Neighborhood Hits	18
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

NU214_HUMAN
θ value	8.99809 (rank : 67)	NC score	0.024298 (rank : 33)
Query Neighborhood Hits	67	Target Neighborhood Hits	657	Shared Neighborhood Hits	15
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

Hits sorted by NC score

REV1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	67	Target Neighborhood Hits	67	Shared Neighborhood Hits	67
SwissProt Accessions	Q920Q2, Q9QXV2	Gene names	Rev1l, Rev1
Domain Architecture	No domain graphic available
Description	DNA repair protein REV1 (EC 2.7.7.-) (Rev1-like terminal deoxycytidyl transferase).

REV1_HUMAN
NC score	0.980203 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	67	Target Neighborhood Hits	56	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UBZ9, O95941, Q9C0J4, Q9NUP2	Gene names	REV1L, REV1
Domain Architecture	No domain graphic available
Description	DNA repair protein REV1 (EC 2.7.7.-) (Rev1-like terminal deoxycytidyl transferase) (Alpha integrin-binding protein 80) (AIBP80).

POLK_MOUSE
NC score	0.579750 (rank : 3)	θ value	1.5773e-20 (rank : 3)
Query Neighborhood Hits	67	Target Neighborhood Hits	66	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QUG2, Q7TPY7	Gene names	Polk, Dinb1
Domain Architecture	No domain graphic available
Description	DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP).

POLI_HUMAN
NC score	0.571333 (rank : 4)	θ value	9.56915e-18 (rank : 4)
Query Neighborhood Hits	67	Target Neighborhood Hits	28	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UNA4, Q8N590, Q9H0S1, Q9NYH6	Gene names	POLI, RAD30B
Domain Architecture	No domain graphic available
Description	DNA polymerase iota (EC 2.7.7.7) (RAD30 homolog B) (Eta2).

POLI_MOUSE
NC score	0.565033 (rank : 5)	θ value	5.25075e-16 (rank : 5)
Query Neighborhood Hits	67	Target Neighborhood Hits	27	Shared Neighborhood Hits	11
SwissProt Accessions	Q6R3M4, Q641P1, Q6R3M3, Q9R1A6	Gene names	Poli, Rad30b
Domain Architecture	No domain graphic available
Description	DNA polymerase iota (EC 2.7.7.7) (Rad30 homolog B).

POLK_HUMAN
NC score	0.558697 (rank : 6)	θ value	1.52774e-15 (rank : 6)
Query Neighborhood Hits	67	Target Neighborhood Hits	64	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UBT6, Q86VJ8, Q8IZY0, Q8IZY1, Q8NB30, Q96L01, Q96Q86, Q96Q87, Q9UHC5	Gene names	POLK, DINB1
Domain Architecture	No domain graphic available
Description	DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP).

POLH_MOUSE
NC score	0.481926 (rank : 7)	θ value	1.9326e-10 (rank : 7)
Query Neighborhood Hits	67	Target Neighborhood Hits	29	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JJN0, Q9JJJ2	Gene names	Polh, Rad30a, Xpv
Domain Architecture	No domain graphic available
Description	DNA polymerase eta (EC 2.7.7.7) (RAD30 homolog A) (Xeroderma pigmentosum variant type protein homolog).

POLH_HUMAN
NC score	0.468484 (rank : 8)	θ value	2.79066e-09 (rank : 8)
Query Neighborhood Hits	67	Target Neighborhood Hits	44	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y253, Q7L8E3, Q96BC4, Q9BX13	Gene names	POLH, RAD30, RAD30A, XPV
Domain Architecture	No domain graphic available
Description	DNA polymerase eta (EC 2.7.7.7) (RAD30 homolog A) (Xeroderma pigmentosum variant type protein).

XRCC1_HUMAN
NC score	0.131154 (rank : 9)	θ value	0.000461057 (rank : 9)
Query Neighborhood Hits	67	Target Neighborhood Hits	131	Shared Neighborhood Hits	5
SwissProt Accessions	P18887, Q9HCB1	Gene names	XRCC1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

TOPB1_HUMAN
NC score	0.130748 (rank : 10)	θ value	0.00175202 (rank : 10)
Query Neighborhood Hits	67	Target Neighborhood Hits	82	Shared Neighborhood Hits	6
SwissProt Accessions	Q92547, Q7LGC1, Q9UEB9	Gene names	TOPBP1, KIAA0259
Domain Architecture	No domain graphic available
Description	DNA topoisomerase 2-binding protein 1 (DNA topoisomerase II-binding protein 1) (DNA topoisomerase IIbeta-binding protein 1) (TopBP1).

XRCC1_MOUSE
NC score	0.111396 (rank : 11)	θ value	0.0330416 (rank : 14)
Query Neighborhood Hits	67	Target Neighborhood Hits	242	Shared Neighborhood Hits	8
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

TOPB1_MOUSE
NC score	0.096992 (rank : 12)	θ value	0.365318 (rank : 18)
Query Neighborhood Hits	67	Target Neighborhood Hits	89	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZQF0, Q6P6P0, Q80Y33, Q8BUI0, Q8BUK1, Q8R348, Q91VX3, Q922X8	Gene names	Topbp1, Kiaa0259
Domain Architecture	No domain graphic available
Description	DNA topoisomerase II-binding protein 1 (DNA topoisomerase IIbeta- binding protein 1) (TopBP1).

HUWE1_MOUSE
NC score	0.065331 (rank : 13)	θ value	0.0193708 (rank : 12)
Query Neighborhood Hits	67	Target Neighborhood Hits	406	Shared Neighborhood Hits	17
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

HUWE1_HUMAN
NC score	0.062091 (rank : 14)	θ value	0.0330416 (rank : 13)
Query Neighborhood Hits	67	Target Neighborhood Hits	443	Shared Neighborhood Hits	14
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

TRRAP_HUMAN
NC score	0.047772 (rank : 15)	θ value	0.0736092 (rank : 15)
Query Neighborhood Hits	67	Target Neighborhood Hits	117	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y4A5, O75218, Q9Y631, Q9Y6H4	Gene names	TRRAP, PAF400
Domain Architecture
Description	Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog).

CU059_HUMAN
NC score	0.047079 (rank : 16)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	67	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	P57076	Gene names	C21orf59, C21orf48
Domain Architecture	No domain graphic available
Description	Protein C21orf59.

ADDA_MOUSE
NC score	0.043847 (rank : 17)	θ value	0.365318 (rank : 17)
Query Neighborhood Hits	67	Target Neighborhood Hits	198	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QYC0, Q9JLE3	Gene names	Add1
Domain Architecture
Description	Alpha-adducin (Erythrocyte adducin subunit alpha).

CI090_MOUSE
NC score	0.043426 (rank : 18)	θ value	2.36792 (rank : 39)
Query Neighborhood Hits	67	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PFD7	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf90 homolog.

CI090_HUMAN
NC score	0.043330 (rank : 19)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	67	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q69YI7, Q8WU12	Gene names	C9orf90
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf90.

ADDA_HUMAN
NC score	0.035615 (rank : 20)	θ value	1.38821 (rank : 26)
Query Neighborhood Hits	67	Target Neighborhood Hits	108	Shared Neighborhood Hits	5
SwissProt Accessions	P35611, Q13734, Q14729, Q16156, Q9UJB6	Gene names	ADD1, ADDA
Domain Architecture
Description	Alpha-adducin (Erythrocyte adducin subunit alpha).

NU133_MOUSE
NC score	0.034797 (rank : 21)	θ value	1.81305 (rank : 36)
Query Neighborhood Hits	67	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R0G9	Gene names	Nup133
Domain Architecture
Description	Nuclear pore complex protein Nup133 (Nucleoporin Nup133) (133 kDa nucleoporin).

K0329_HUMAN
NC score	0.033623 (rank : 22)	θ value	1.81305 (rank : 35)
Query Neighborhood Hits	67	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	O15040, Q9UEG6	Gene names	KIAA0329, KIAA0297
Domain Architecture
Description	Protein KIAA0329/KIAA0297.

GSCR1_HUMAN
NC score	0.032676 (rank : 23)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	67	Target Neighborhood Hits	674	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

CMTA2_MOUSE
NC score	0.030975 (rank : 24)	θ value	0.813845 (rank : 21)
Query Neighborhood Hits	67	Target Neighborhood Hits	216	Shared Neighborhood Hits	7
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

MUC1_HUMAN
NC score	0.029148 (rank : 25)	θ value	0.163984 (rank : 16)
Query Neighborhood Hits	67	Target Neighborhood Hits	975	Shared Neighborhood Hits	24
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

RUSC2_MOUSE
NC score	0.029095 (rank : 26)	θ value	1.38821 (rank : 30)
Query Neighborhood Hits	67	Target Neighborhood Hits	305	Shared Neighborhood Hits	10
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

AP180_HUMAN
NC score	0.028521 (rank : 27)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	67	Target Neighborhood Hits	183	Shared Neighborhood Hits	11
SwissProt Accessions	O60641, Q5JX13, Q68DL9, Q6P9D3, Q9NTY7	Gene names	SNAP91, KIAA0656
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein).

BRD4_HUMAN
NC score	0.027822 (rank : 28)	θ value	1.38821 (rank : 27)
Query Neighborhood Hits	67	Target Neighborhood Hits	851	Shared Neighborhood Hits	18
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

OXR1_MOUSE
NC score	0.027557 (rank : 29)	θ value	1.06291 (rank : 23)
Query Neighborhood Hits	67	Target Neighborhood Hits	516	Shared Neighborhood Hits	12
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

LYRIC_MOUSE
NC score	0.026528 (rank : 30)	θ value	2.36792 (rank : 41)
Query Neighborhood Hits	67	Target Neighborhood Hits	126	Shared Neighborhood Hits	4
SwissProt Accessions	Q80WJ7, Q3U9F8, Q3UAQ8, Q8BN67, Q8CBT9, Q8CDL0, Q8CGI7, Q9D052	Gene names	Mtdh, Lyric
Domain Architecture	No domain graphic available
Description	Protein LYRIC (Lysine-rich CEACAM1 co-isolated protein) (3D3/LYRIC) (Metastasis adhesion protein) (Metadherin).

EP300_HUMAN
NC score	0.026242 (rank : 31)	θ value	1.38821 (rank : 29)
Query Neighborhood Hits	67	Target Neighborhood Hits	821	Shared Neighborhood Hits	19
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

TAF4_HUMAN
NC score	0.024595 (rank : 32)	θ value	6.88961 (rank : 65)
Query Neighborhood Hits	67	Target Neighborhood Hits	687	Shared Neighborhood Hits	16
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

NU214_HUMAN
NC score	0.024298 (rank : 33)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	67	Target Neighborhood Hits	657	Shared Neighborhood Hits	15
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

BRD4_MOUSE
NC score	0.024289 (rank : 34)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	67	Target Neighborhood Hits	845	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

NFRKB_HUMAN
NC score	0.023569 (rank : 35)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	67	Target Neighborhood Hits	211	Shared Neighborhood Hits	11
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

ZYX_MOUSE
NC score	0.021979 (rank : 36)	θ value	1.06291 (rank : 24)
Query Neighborhood Hits	67	Target Neighborhood Hits	347	Shared Neighborhood Hits	12
SwissProt Accessions	Q62523, P70461	Gene names	Zyx
Domain Architecture
Description	Zyxin.

PHLB1_HUMAN
NC score	0.020886 (rank : 37)	θ value	2.36792 (rank : 42)
Query Neighborhood Hits	67	Target Neighborhood Hits	1038	Shared Neighborhood Hits	22
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

MAGC1_HUMAN
NC score	0.020667 (rank : 38)	θ value	0.813845 (rank : 22)
Query Neighborhood Hits	67	Target Neighborhood Hits	431	Shared Neighborhood Hits	17
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

TACC2_HUMAN
NC score	0.019454 (rank : 39)	θ value	0.62314 (rank : 20)
Query Neighborhood Hits	67	Target Neighborhood Hits	856	Shared Neighborhood Hits	10
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

TAB2_MOUSE
NC score	0.019304 (rank : 40)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	67	Target Neighborhood Hits	245	Shared Neighborhood Hits	5
SwissProt Accessions	Q99K90, Q3UGP1, Q8BTP4, Q8CHD3, Q99KP4	Gene names	Map3k7ip2, Kiaa0733, Tab2
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 2 (TAK1-binding protein 2) (TAB2).

CT160_HUMAN
NC score	0.019184 (rank : 41)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	67	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NUG4, Q5JYR9, Q8N5F1, Q8N6G8, Q96MD5	Gene names	C20orf160
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf160.

ECHA_HUMAN
NC score	0.018903 (rank : 42)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	67	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	P40939, Q16679, Q96GT7	Gene names	HADHA, HADH
Domain Architecture
Description	Trifunctional enzyme subunit alpha, mitochondrial precursor (TP-alpha) (78 kDa gastrin-binding protein) [Includes: Long-chain enoyl-CoA hydratase (EC 4.2.1.17); Long chain 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.211)].

K1802_MOUSE
NC score	0.018161 (rank : 43)	θ value	2.36792 (rank : 40)
Query Neighborhood Hits	67	Target Neighborhood Hits	1596	Shared Neighborhood Hits	28
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

CN103_HUMAN
NC score	0.017664 (rank : 44)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	67	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q96BY7, Q6ZRE7, Q9NW80	Gene names	C14orf103
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf103.

MAST4_HUMAN
NC score	0.017403 (rank : 45)	θ value	0.00390308 (rank : 11)
Query Neighborhood Hits	67	Target Neighborhood Hits	1804	Shared Neighborhood Hits	31
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

SDCG1_HUMAN
NC score	0.017327 (rank : 46)	θ value	5.27518 (rank : 57)
Query Neighborhood Hits	67	Target Neighborhood Hits	190	Shared Neighborhood Hits	4
SwissProt Accessions	O60524, Q8WW70, Q9NWG1	Gene names	SDCCAG1
Domain Architecture
Description	Serologically defined colon cancer antigen 1 (Antigen NY-CO-1).

RIN3_HUMAN
NC score	0.016895 (rank : 47)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	67	Target Neighborhood Hits	227	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

HDAC9_MOUSE
NC score	0.016793 (rank : 48)	θ value	4.03905 (rank : 49)
Query Neighborhood Hits	67	Target Neighborhood Hits	186	Shared Neighborhood Hits	5
SwissProt Accessions	Q99N13, Q9EPT2	Gene names	Hdac9, Hdac7b, Hdrp, Mitr
Domain Architecture	No domain graphic available
Description	Histone deacetylase 9 (HD9) (HD7B) (Histone deacetylase-related protein) (MEF2-interacting transcription repressor MITR).

ANR38_MOUSE
NC score	0.016626 (rank : 49)	θ value	1.81305 (rank : 32)
Query Neighborhood Hits	67	Target Neighborhood Hits	512	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ZN318_HUMAN
NC score	0.016016 (rank : 50)	θ value	5.27518 (rank : 58)
Query Neighborhood Hits	67	Target Neighborhood Hits	497	Shared Neighborhood Hits	6
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

CSKI1_MOUSE
NC score	0.015728 (rank : 51)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	67	Target Neighborhood Hits	1031	Shared Neighborhood Hits	22
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

BPTF_HUMAN
NC score	0.015491 (rank : 52)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	67	Target Neighborhood Hits	786	Shared Neighborhood Hits	18
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

CE005_MOUSE
NC score	0.015328 (rank : 53)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	67	Target Neighborhood Hits	238	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

MLL3_MOUSE
NC score	0.015156 (rank : 54)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	67	Target Neighborhood Hits	1399	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

B3A3_HUMAN
NC score	0.014048 (rank : 55)	θ value	1.81305 (rank : 33)
Query Neighborhood Hits	67	Target Neighborhood Hits	119	Shared Neighborhood Hits	6
SwissProt Accessions	P48751	Gene names	SLC4A3, AE3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3) (Cardiac/brain band 3-like protein) (CAE3/BAE3).

HCFC2_HUMAN
NC score	0.013388 (rank : 56)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	67	Target Neighborhood Hits	154	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5Z7	Gene names	HCFC2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

CE005_HUMAN
NC score	0.013034 (rank : 57)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	67	Target Neighborhood Hits	213	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

LIMA1_HUMAN
NC score	0.012162 (rank : 58)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	67	Target Neighborhood Hits	309	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UHB6, Q2TAN7, Q9BVF2, Q9H8J1, Q9HBN5, Q9NX96, Q9NXC3, Q9NXU6, Q9P0H8, Q9UHB5	Gene names	LIMA1, EPLIN, SREBP3
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm).

BCOR_HUMAN
NC score	0.012135 (rank : 59)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	67	Target Neighborhood Hits	609	Shared Neighborhood Hits	14
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

PDLI5_HUMAN
NC score	0.010516 (rank : 60)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	67	Target Neighborhood Hits	322	Shared Neighborhood Hits	8
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

KIRR3_MOUSE
NC score	0.010149 (rank : 61)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	67	Target Neighborhood Hits	292	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BR86, Q6P555, Q810H3, Q8BGQ5, Q8BRS8	Gene names	Kirrel3, Kiaa1867
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3).

PLCD1_MOUSE
NC score	0.009103 (rank : 62)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	67	Target Neighborhood Hits	106	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R3B1	Gene names	Plcd1, Plcd
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

ACK1_MOUSE
NC score	0.008080 (rank : 63)	θ value	1.81305 (rank : 31)
Query Neighborhood Hits	67	Target Neighborhood Hits	1080	Shared Neighborhood Hits	15
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

ACK1_HUMAN
NC score	0.007982 (rank : 64)	θ value	1.38821 (rank : 25)
Query Neighborhood Hits	67	Target Neighborhood Hits	1140	Shared Neighborhood Hits	17
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

PHLPP_MOUSE
NC score	0.006818 (rank : 65)	θ value	4.03905 (rank : 50)
Query Neighborhood Hits	67	Target Neighborhood Hits	394	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CHE4, Q6PCN0, Q8QZU8, Q8R5E5, Q99KL6	Gene names	Phlpp, Kiaa0606, Plekhe1, Scop
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein).

BRSK2_HUMAN
NC score	0.006621 (rank : 66)	θ value	0.62314 (rank : 19)
Query Neighborhood Hits	67	Target Neighborhood Hits	897	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IWQ3, O60843, O95099, Q5J5B4, Q8TB60	Gene names	BRSK2, C11orf7, PEN11B, STK29
Domain Architecture
Description	BR serine/threonine-protein kinase 2 (EC 2.7.11.1) (Serine/threonine- protein kinase 29) (SAD1B).

SN1L1_HUMAN
NC score	0.003891 (rank : 67)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	67	Target Neighborhood Hits	911	Shared Neighborhood Hits	8
SwissProt Accessions	P57059, Q5R2V5, Q86YJ2	Gene names	SNF1LK
Domain Architecture
Description	Serine/threonine-protein kinase SNF1-like kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase SNF1LK).