Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : B3A3_HUMAN

For an explanation of this page, click here

B3A3_HUMAN
SwissProt Accessions	P48751	Gene names	SLC4A3, AE3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3) (Cardiac/brain band 3-like protein) (CAE3/BAE3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

B3A2_HUMAN
θ value	0 (rank : 1)	NC score	0.986841 (rank : 3)
Query Neighborhood Hits	119	Target Neighborhood Hits	57	Shared Neighborhood Hits	19
SwissProt Accessions	P04920, Q45EY5, Q969L3	Gene names	SLC4A2, AE2, EPB3L1, HKB3, MPB3L
Domain Architecture
Description	Anion exchange protein 2 (Non-erythroid band 3-like protein) (AE2 anion exchanger) (Solute carrier family 4 member 2) (BND3L).

B3A2_MOUSE
θ value	0 (rank : 2)	NC score	0.986343 (rank : 4)
Query Neighborhood Hits	119	Target Neighborhood Hits	64	Shared Neighborhood Hits	18
SwissProt Accessions	P13808, Q9ES09, Q9ES10, Q9ES11, Q9ES12, Q9ES13	Gene names	Slc4a2, Ae2
Domain Architecture
Description	Anion exchange protein 2 (Non-erythroid band 3-like protein) (AE2 anion exchanger) (Solute carrier family 4 member 2) (B3RP).

B3A3_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	119	Target Neighborhood Hits	119	Shared Neighborhood Hits	119
SwissProt Accessions	P48751	Gene names	SLC4A3, AE3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3) (Cardiac/brain band 3-like protein) (CAE3/BAE3).

B3A3_MOUSE
θ value	0 (rank : 4)	NC score	0.993637 (rank : 2)
Query Neighborhood Hits	119	Target Neighborhood Hits	112	Shared Neighborhood Hits	59
SwissProt Accessions	P16283	Gene names	Slc4a3, Ae3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3).

B3AT_HUMAN
θ value	0 (rank : 5)	NC score	0.985394 (rank : 5)
Query Neighborhood Hits	119	Target Neighborhood Hits	31	Shared Neighborhood Hits	15
SwissProt Accessions	P02730, P78487, Q4VB84	Gene names	SLC4A1, AE1, DI, EPB3
Domain Architecture
Description	Band 3 anion transport protein (Anion exchange protein 1) (AE 1) (Solute carrier family 4 member 1) (CD233 antigen).

B3AT_MOUSE
θ value	0 (rank : 6)	NC score	0.984730 (rank : 6)
Query Neighborhood Hits	119	Target Neighborhood Hits	23	Shared Neighborhood Hits	14
SwissProt Accessions	P04919	Gene names	Slc4a1, Ae1
Domain Architecture
Description	Band 3 anion transport protein (Anion exchange protein 1) (AE 1) (Solute carrier family 4 member 1) (MEB3) (CD233 antigen).

S4A10_HUMAN
θ value	0 (rank : 7)	NC score	0.967026 (rank : 10)
Query Neighborhood Hits	119	Target Neighborhood Hits	33	Shared Neighborhood Hits	15
SwissProt Accessions	Q6U841, Q4ZFX6, Q8TCP2, Q9HCQ6	Gene names	SLC4A10, NCBE
Domain Architecture	No domain graphic available
Description	Sodium-driven chloride bicarbonate exchanger (Solute carrier family 4 member 10).

S4A4_HUMAN
θ value	4.23373e-183 (rank : 8)	NC score	0.969625 (rank : 7)
Query Neighborhood Hits	119	Target Neighborhood Hits	33	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y6R1, O15153, Q8NEJ2, Q9H262, Q9NRZ1, Q9UIC0, Q9UIC1, Q9UP50	Gene names	SLC4A4, NBC, NBC1, NBCE1
Domain Architecture	No domain graphic available
Description	Electrogenic sodium bicarbonate cotransporter 1 (Sodium bicarbonate cotransporter) (Na(+)/HCO3(-) cotransporter) (Solute carrier family 4 member 4) (kNBC1).

S4A4_MOUSE
θ value	7.22167e-183 (rank : 9)	NC score	0.969217 (rank : 8)
Query Neighborhood Hits	119	Target Neighborhood Hits	31	Shared Neighborhood Hits	14
SwissProt Accessions	O88343, Q3USE4, Q8BUG0, Q8QZR9, Q9R1C4	Gene names	Slc4a4, Nbc1, Nbce1
Domain Architecture	No domain graphic available
Description	Electrogenic sodium bicarbonate cotransporter 1 (Sodium bicarbonate cotransporter) (Na(+)/HCO3(-) cotransporter) (Solute carrier family 4 member 4).

S4A10_MOUSE
θ value	1.07914e-178 (rank : 10)	NC score	0.966362 (rank : 11)
Query Neighborhood Hits	119	Target Neighborhood Hits	23	Shared Neighborhood Hits	14
SwissProt Accessions	Q5DTL9, Q8CFS3, Q9EST0	Gene names	Slc4a10, Kiaa4136, Ncbe
Domain Architecture	No domain graphic available
Description	Sodium-driven chloride bicarbonate exchanger (Solute carrier family 4 member 10).

S4A7_HUMAN
θ value	1.42253e-146 (rank : 11)	NC score	0.961967 (rank : 12)
Query Neighborhood Hits	119	Target Neighborhood Hits	55	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y6M7, O60350, Q6AHZ9, Q9HC88, Q9UIB9	Gene names	SLC4A7, BT, NBC2, NBC2B, NBC3, SBC2, SLC4A6
Domain Architecture	No domain graphic available
Description	Sodium bicarbonate cotransporter 3 (Sodium bicarbonate cotransporter 2) (Sodium bicarbonate cotransporter 2b) (Bicarbonate transporter) (Solute carrier family 4 member 7).

B3A4_HUMAN
θ value	1.09172e-138 (rank : 12)	NC score	0.967903 (rank : 9)
Query Neighborhood Hits	119	Target Neighborhood Hits	28	Shared Neighborhood Hits	14
SwissProt Accessions	Q96Q91, Q96RM5, Q9BXF2, Q9BXN3	Gene names	SLC4A9, AE4, SBC5
Domain Architecture
Description	Anion exchange protein 4 (Anion exchanger 4) (Solute carrier family 4 member 9) (Sodium bicarbonate cotransporter 5).

S4A7_MOUSE
θ value	6.43005e-123 (rank : 13)	NC score	0.956527 (rank : 13)
Query Neighborhood Hits	119	Target Neighborhood Hits	30	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BTY2, Q3U5H7	Gene names	Slc4a7, Nbc3
Domain Architecture	No domain graphic available
Description	Sodium bicarbonate cotransporter 3 (Solute carrier family 4 member 7).

S4A11_HUMAN
θ value	1.36902e-48 (rank : 14)	NC score	0.915941 (rank : 14)
Query Neighborhood Hits	119	Target Neighborhood Hits	23	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NBS3, Q9BXF4, Q9NTW9	Gene names	SLC4A11, BTR1
Domain Architecture
Description	Sodium bicarbonate transporter-like protein 11 (Bicarbonate transporter-related protein 1) (Solute carrier family 4 member 11).

NIPBL_HUMAN
θ value	0.000786445 (rank : 15)	NC score	0.038108 (rank : 17)
Query Neighborhood Hits	119	Target Neighborhood Hits	1311	Shared Neighborhood Hits	40
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

OGFR_MOUSE
θ value	0.00665767 (rank : 16)	NC score	0.035627 (rank : 19)
Query Neighborhood Hits	119	Target Neighborhood Hits	584	Shared Neighborhood Hits	28
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

SLIK3_MOUSE
θ value	0.0113563 (rank : 17)	NC score	0.019006 (rank : 45)
Query Neighborhood Hits	119	Target Neighborhood Hits	308	Shared Neighborhood Hits	4
SwissProt Accessions	Q810B9	Gene names	Slitrk3
Domain Architecture
Description	SLIT and NTRK-like protein 3 precursor.

PHAR3_MOUSE
θ value	0.0148317 (rank : 18)	NC score	0.037380 (rank : 18)
Query Neighborhood Hits	119	Target Neighborhood Hits	206	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BYK5, Q8BYS8, Q8C058, Q9DB87	Gene names	Phactr3, Scapin1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 3 (Scapinin) (Scaffold-associated PP1- inhibiting protein).

NFH_MOUSE
θ value	0.0193708 (rank : 19)	NC score	0.021355 (rank : 37)
Query Neighborhood Hits	119	Target Neighborhood Hits	2247	Shared Neighborhood Hits	63
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

TENS1_HUMAN
θ value	0.0736092 (rank : 20)	NC score	0.029486 (rank : 22)
Query Neighborhood Hits	119	Target Neighborhood Hits	400	Shared Neighborhood Hits	25
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

MA1B1_HUMAN
θ value	0.0961366 (rank : 21)	NC score	0.030534 (rank : 21)
Query Neighborhood Hits	119	Target Neighborhood Hits	125	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UKM7, Q5VSG3, Q9BRS9, Q9Y5K7	Gene names	MAN1B1
Domain Architecture
Description	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (Mannosidase alpha class 1B member 1) (Man9GlcNAc2-specific-processing alpha-mannosidase).

ERCC1_HUMAN
θ value	0.279714 (rank : 22)	NC score	0.041065 (rank : 16)
Query Neighborhood Hits	119	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	P07992	Gene names	ERCC1
Domain Architecture
Description	DNA excision repair protein ERCC-1.

NTKL_MOUSE
θ value	0.279714 (rank : 23)	NC score	0.018727 (rank : 46)
Query Neighborhood Hits	119	Target Neighborhood Hits	326	Shared Neighborhood Hits	6
SwissProt Accessions	Q9EQC5, Q3TST7, Q3UKU0, Q8K222	Gene names	Scyl1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like protein (SCY1-like protein 1) (105 kDa kinase- like protein) (Mitosis-associated kinase-like protein NTKL).

DVL3_HUMAN
θ value	0.365318 (rank : 24)	NC score	0.020459 (rank : 40)
Query Neighborhood Hits	119	Target Neighborhood Hits	194	Shared Neighborhood Hits	8
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

MDC1_MOUSE
θ value	0.365318 (rank : 25)	NC score	0.029182 (rank : 23)
Query Neighborhood Hits	119	Target Neighborhood Hits	998	Shared Neighborhood Hits	46
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

CASC3_MOUSE
θ value	0.47712 (rank : 26)	NC score	0.031908 (rank : 20)
Query Neighborhood Hits	119	Target Neighborhood Hits	333	Shared Neighborhood Hits	21
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

PHLB1_HUMAN
θ value	0.47712 (rank : 27)	NC score	0.015931 (rank : 55)
Query Neighborhood Hits	119	Target Neighborhood Hits	1038	Shared Neighborhood Hits	31
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

SMC4_MOUSE
θ value	0.47712 (rank : 28)	NC score	0.011015 (rank : 77)
Query Neighborhood Hits	119	Target Neighborhood Hits	830	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

TLK2_HUMAN
θ value	0.47712 (rank : 29)	NC score	0.000972 (rank : 117)
Query Neighborhood Hits	119	Target Neighborhood Hits	1044	Shared Neighborhood Hits	12
SwissProt Accessions	Q86UE8, Q9UKI7, Q9Y4F7	Gene names	TLK2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2) (PKU-alpha).

BTBD7_HUMAN
θ value	0.62314 (rank : 30)	NC score	0.020447 (rank : 41)
Query Neighborhood Hits	119	Target Neighborhood Hits	176	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P203, Q69Z05, Q7Z308, Q86TS0, Q9HAA4, Q9NVM0	Gene names	BTBD7, KIAA1525
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 7.

ETV3_HUMAN
θ value	0.62314 (rank : 31)	NC score	0.018575 (rank : 47)
Query Neighborhood Hits	119	Target Neighborhood Hits	312	Shared Neighborhood Hits	17
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

MAP9_MOUSE
θ value	0.62314 (rank : 32)	NC score	0.024278 (rank : 29)
Query Neighborhood Hits	119	Target Neighborhood Hits	529	Shared Neighborhood Hits	12
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

TXND2_HUMAN
θ value	0.62314 (rank : 33)	NC score	0.026128 (rank : 27)
Query Neighborhood Hits	119	Target Neighborhood Hits	793	Shared Neighborhood Hits	36
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

NACAM_MOUSE
θ value	0.813845 (rank : 34)	NC score	0.017510 (rank : 50)
Query Neighborhood Hits	119	Target Neighborhood Hits	1866	Shared Neighborhood Hits	55
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

K1802_MOUSE
θ value	1.06291 (rank : 35)	NC score	0.015025 (rank : 59)
Query Neighborhood Hits	119	Target Neighborhood Hits	1596	Shared Neighborhood Hits	41
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MYBB_MOUSE
θ value	1.06291 (rank : 36)	NC score	0.019176 (rank : 44)
Query Neighborhood Hits	119	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	P48972	Gene names	Mybl2, Bmyb
Domain Architecture
Description	Myb-related protein B (B-Myb).

SLIK3_HUMAN
θ value	1.06291 (rank : 37)	NC score	0.011176 (rank : 74)
Query Neighborhood Hits	119	Target Neighborhood Hits	298	Shared Neighborhood Hits	5
SwissProt Accessions	O94933	Gene names	SLITRK3, KIAA0848
Domain Architecture	No domain graphic available
Description	SLIT and NTRK-like protein 3 precursor.

SPEG_MOUSE
θ value	1.06291 (rank : 38)	NC score	0.002588 (rank : 112)
Query Neighborhood Hits	119	Target Neighborhood Hits	1959	Shared Neighborhood Hits	43
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

CO002_HUMAN
θ value	1.38821 (rank : 39)	NC score	0.025422 (rank : 28)
Query Neighborhood Hits	119	Target Neighborhood Hits	387	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

DVL3_MOUSE
θ value	1.38821 (rank : 40)	NC score	0.014064 (rank : 64)
Query Neighborhood Hits	119	Target Neighborhood Hits	198	Shared Neighborhood Hits	5
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

LCP2_HUMAN
θ value	1.38821 (rank : 41)	NC score	0.015645 (rank : 57)
Query Neighborhood Hits	119	Target Neighborhood Hits	531	Shared Neighborhood Hits	23
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

DCBD2_MOUSE
θ value	1.81305 (rank : 42)	NC score	0.010788 (rank : 79)
Query Neighborhood Hits	119	Target Neighborhood Hits	113	Shared Neighborhood Hits	4
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

MLL2_HUMAN
θ value	1.81305 (rank : 43)	NC score	0.019190 (rank : 43)
Query Neighborhood Hits	119	Target Neighborhood Hits	1788	Shared Neighborhood Hits	56
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

REV1_MOUSE
θ value	1.81305 (rank : 44)	NC score	0.014048 (rank : 65)
Query Neighborhood Hits	119	Target Neighborhood Hits	67	Shared Neighborhood Hits	6
SwissProt Accessions	Q920Q2, Q9QXV2	Gene names	Rev1l, Rev1
Domain Architecture	No domain graphic available
Description	DNA repair protein REV1 (EC 2.7.7.-) (Rev1-like terminal deoxycytidyl transferase).

SNPC2_MOUSE
θ value	1.81305 (rank : 45)	NC score	0.024074 (rank : 31)
Query Neighborhood Hits	119	Target Neighborhood Hits	83	Shared Neighborhood Hits	6
SwissProt Accessions	Q91XA5, Q3UK17, Q8CBS9	Gene names	Snapc2
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 2 (SNAPc subunit 2) (snRNA- activating protein complex 45 kDa subunit) (SNAPc 45 kDa subunit) (Small nuclear RNA-activating complex polypeptide 2).

TCAL5_HUMAN
θ value	1.81305 (rank : 46)	NC score	0.013822 (rank : 66)
Query Neighborhood Hits	119	Target Neighborhood Hits	806	Shared Neighborhood Hits	24
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

ZN690_HUMAN
θ value	1.81305 (rank : 47)	NC score	-0.002014 (rank : 119)
Query Neighborhood Hits	119	Target Neighborhood Hits	777	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IWY8, Q32M75, Q32M76, Q8NA40	Gene names	ZNF690
Domain Architecture	No domain graphic available
Description	Zinc finger protein 690.

ADDB_MOUSE
θ value	2.36792 (rank : 48)	NC score	0.018063 (rank : 48)
Query Neighborhood Hits	119	Target Neighborhood Hits	574	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

BCAS1_MOUSE
θ value	2.36792 (rank : 49)	NC score	0.023456 (rank : 32)
Query Neighborhood Hits	119	Target Neighborhood Hits	215	Shared Neighborhood Hits	20
SwissProt Accessions	Q80YN3, Q9CVA1	Gene names	Bcas1, Nabc1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 1 homolog (Novel amplified in breast cancer 1 homolog).

CT151_HUMAN
θ value	2.36792 (rank : 50)	NC score	0.021357 (rank : 36)
Query Neighborhood Hits	119	Target Neighborhood Hits	382	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

HCN4_HUMAN
θ value	2.36792 (rank : 51)	NC score	0.009960 (rank : 82)
Query Neighborhood Hits	119	Target Neighborhood Hits	303	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

I28RA_HUMAN
θ value	2.36792 (rank : 52)	NC score	0.024188 (rank : 30)
Query Neighborhood Hits	119	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IU57, Q6ZML8, Q8IZI7, Q8IZI8	Gene names	IL28RA, IFNLR1, LICR2
Domain Architecture	No domain graphic available
Description	Interleukin-28 receptor alpha chain precursor (IL-28R-alpha) (IL-28RA) (Cytokine receptor family 2 member 12) (Cytokine receptor class-II member 12) (CRF2-12) (Interferon lambda receptor 1) (IFN-lambda R1) (Likely interleukin or cytokine receptor 2).

MBB1A_HUMAN
θ value	2.36792 (rank : 53)	NC score	0.023255 (rank : 33)
Query Neighborhood Hits	119	Target Neighborhood Hits	665	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

NPBL_MOUSE
θ value	2.36792 (rank : 54)	NC score	0.027491 (rank : 24)
Query Neighborhood Hits	119	Target Neighborhood Hits	1041	Shared Neighborhood Hits	32
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

NTKL_HUMAN
θ value	2.36792 (rank : 55)	NC score	0.017269 (rank : 51)
Query Neighborhood Hits	119	Target Neighborhood Hits	266	Shared Neighborhood Hits	6
SwissProt Accessions	Q96KG9, Q96G50, Q96KG8, Q96KH1, Q9HAW5, Q9HBL3, Q9NR53	Gene names	SCYL1, GKLP, NTKL, TAPK, TEIF, TRAP
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like protein (SCY1-like protein 1) (Teratoma- associated tyrosine kinase) (Telomerase transcriptional element- interacting factor) (Telomerase regulation-associated protein).

SC24C_HUMAN
θ value	2.36792 (rank : 56)	NC score	0.013158 (rank : 68)
Query Neighborhood Hits	119	Target Neighborhood Hits	662	Shared Neighborhood Hits	33
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SMAD9_MOUSE
θ value	2.36792 (rank : 57)	NC score	0.006731 (rank : 97)
Query Neighborhood Hits	119	Target Neighborhood Hits	75	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JIW5, Q8CFF9	Gene names	Smad9, Madh8, Madh9, Smad8
Domain Architecture
Description	Mothers against decapentaplegic homolog 9 (SMAD 9) (Mothers against DPP homolog 9) (Smad9) (Smad8).

ZIC5_HUMAN
θ value	2.36792 (rank : 58)	NC score	-0.001265 (rank : 118)
Query Neighborhood Hits	119	Target Neighborhood Hits	774	Shared Neighborhood Hits	12
SwissProt Accessions	Q96T25	Gene names	ZIC5
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZIC 5 (Zinc finger protein of the cerebellum 5).

DOCK8_HUMAN
θ value	3.0926 (rank : 59)	NC score	0.012508 (rank : 71)
Query Neighborhood Hits	119	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NF50, Q3MV16, Q5JPJ1, Q8TEP1, Q8WUY2, Q9BYJ5, Q9H1Q2, Q9H1Q3, Q9H308, Q9H7P2	Gene names	DOCK8
Domain Architecture	No domain graphic available
Description	Dedicator of cytokinesis protein 8.

FRS3_MOUSE
θ value	3.0926 (rank : 60)	NC score	0.022972 (rank : 34)
Query Neighborhood Hits	119	Target Neighborhood Hits	168	Shared Neighborhood Hits	10
SwissProt Accessions	Q91WJ0	Gene names	Frs3, Frs2b
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (FRS2-beta).

PO121_MOUSE
θ value	3.0926 (rank : 61)	NC score	0.022622 (rank : 35)
Query Neighborhood Hits	119	Target Neighborhood Hits	345	Shared Neighborhood Hits	24
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

TNFL6_MOUSE
θ value	3.0926 (rank : 62)	NC score	0.015756 (rank : 56)
Query Neighborhood Hits	119	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	P41047, Q61217, Q9R1F2	Gene names	Faslg, Apt1lg1, Fasl, gld, Tnfsf6
Domain Architecture
Description	Tumor necrosis factor ligand superfamily member 6 (Fas antigen ligand) (Fas ligand) (CD178 antigen) (CD95L protein) [Contains: Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form].

ANXA7_MOUSE
θ value	4.03905 (rank : 63)	NC score	0.004270 (rank : 107)
Query Neighborhood Hits	119	Target Neighborhood Hits	142	Shared Neighborhood Hits	7
SwissProt Accessions	Q07076	Gene names	Anxa7, Anx7
Domain Architecture
Description	Annexin A7 (Annexin VII) (Synexin).

CCDC8_HUMAN
θ value	4.03905 (rank : 64)	NC score	0.020947 (rank : 39)
Query Neighborhood Hits	119	Target Neighborhood Hits	70	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H0W5, Q8TB26	Gene names	CCDC8
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 8.

CLMN_HUMAN
θ value	4.03905 (rank : 65)	NC score	0.005477 (rank : 103)
Query Neighborhood Hits	119	Target Neighborhood Hits	205	Shared Neighborhood Hits	8
SwissProt Accessions	Q96JQ2, Q9H713, Q9HA23, Q9HA57, Q9UFP4, Q9ULN2	Gene names	CLMN, KIAA1188
Domain Architecture
Description	Calmin.

CSKI1_MOUSE
θ value	4.03905 (rank : 66)	NC score	0.005962 (rank : 100)
Query Neighborhood Hits	119	Target Neighborhood Hits	1031	Shared Neighborhood Hits	39
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

DAZP2_MOUSE
θ value	4.03905 (rank : 67)	NC score	0.015068 (rank : 58)
Query Neighborhood Hits	119	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DCP9, O88675, Q3UVI4	Gene names	Dazap2, Prtb
Domain Architecture	No domain graphic available
Description	DAZ-associated protein 2 (Deleted in azoospermia-associated protein 2) (Proline-rich protein expressed in brain).

GTSE1_HUMAN
θ value	4.03905 (rank : 68)	NC score	0.021065 (rank : 38)
Query Neighborhood Hits	119	Target Neighborhood Hits	193	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NYZ3, Q53GX5, Q5R3I6, Q6DHX4, Q9BRE0, Q9UGZ9, Q9Y557	Gene names	GTSE1
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (B99 homolog).

HCN4_MOUSE
θ value	4.03905 (rank : 69)	NC score	0.009729 (rank : 83)
Query Neighborhood Hits	119	Target Neighborhood Hits	284	Shared Neighborhood Hits	19
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

MAST4_HUMAN
θ value	4.03905 (rank : 70)	NC score	0.001339 (rank : 116)
Query Neighborhood Hits	119	Target Neighborhood Hits	1804	Shared Neighborhood Hits	42
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MKL1_MOUSE
θ value	4.03905 (rank : 71)	NC score	0.014867 (rank : 60)
Query Neighborhood Hits	119	Target Neighborhood Hits	667	Shared Neighborhood Hits	28
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

NCOR2_MOUSE
θ value	4.03905 (rank : 72)	NC score	0.014819 (rank : 61)
Query Neighborhood Hits	119	Target Neighborhood Hits	790	Shared Neighborhood Hits	41
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

PCLO_HUMAN
θ value	4.03905 (rank : 73)	NC score	0.016633 (rank : 52)
Query Neighborhood Hits	119	Target Neighborhood Hits	2046	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

ZN638_MOUSE
θ value	4.03905 (rank : 74)	NC score	0.012154 (rank : 72)
Query Neighborhood Hits	119	Target Neighborhood Hits	318	Shared Neighborhood Hits	9
SwissProt Accessions	Q61464, Q6DFV9, Q8C941	Gene names	Znf638, Np220, Zfml
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein).

BCR_HUMAN
θ value	5.27518 (rank : 75)	NC score	0.007752 (rank : 91)
Query Neighborhood Hits	119	Target Neighborhood Hits	204	Shared Neighborhood Hits	10
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

BT2A2_HUMAN
θ value	5.27518 (rank : 76)	NC score	0.004279 (rank : 106)
Query Neighborhood Hits	119	Target Neighborhood Hits	191	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WVV5, O00480	Gene names	BTN2A2, BT2.2, BTF2
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A2 precursor.

C1QT6_HUMAN
θ value	5.27518 (rank : 77)	NC score	0.006296 (rank : 99)
Query Neighborhood Hits	119	Target Neighborhood Hits	122	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BXI9	Gene names	C1QTNF6, CTRP6
Domain Architecture
Description	Complement C1q tumor necrosis factor-related protein 6 precursor.

CTDP1_HUMAN
θ value	5.27518 (rank : 78)	NC score	0.012567 (rank : 70)
Query Neighborhood Hits	119	Target Neighborhood Hits	416	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

DNMBP_MOUSE
θ value	5.27518 (rank : 79)	NC score	0.006934 (rank : 96)
Query Neighborhood Hits	119	Target Neighborhood Hits	435	Shared Neighborhood Hits	12
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

EMID1_MOUSE
θ value	5.27518 (rank : 80)	NC score	0.009088 (rank : 87)
Query Neighborhood Hits	119	Target Neighborhood Hits	230	Shared Neighborhood Hits	18
SwissProt Accessions	Q91VF5	Gene names	Emid1, Emu1
Domain Architecture	No domain graphic available
Description	EMI domain-containing protein 1 precursor (Protein Emu1) (Emilin and multimerin domain-containing protein 1).

KCNH6_HUMAN
θ value	5.27518 (rank : 81)	NC score	0.007064 (rank : 94)
Query Neighborhood Hits	119	Target Neighborhood Hits	222	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

LSP1_HUMAN
θ value	5.27518 (rank : 82)	NC score	0.013334 (rank : 67)
Query Neighborhood Hits	119	Target Neighborhood Hits	142	Shared Neighborhood Hits	6
SwissProt Accessions	P33241, Q16096, Q9BUY8	Gene names	LSP1, WP34
Domain Architecture	No domain graphic available
Description	Lymphocyte-specific protein 1 (Protein pp52) (52 kDa phosphoprotein) (Lymphocyte-specific antigen WP34) (47 kDa actin-binding protein).

NPM_MOUSE
θ value	5.27518 (rank : 83)	NC score	0.019205 (rank : 42)
Query Neighborhood Hits	119	Target Neighborhood Hits	69	Shared Neighborhood Hits	9
SwissProt Accessions	Q61937	Gene names	Npm1
Domain Architecture
Description	Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Numatrin) (Nucleolar protein NO38).

OGFR_HUMAN
θ value	5.27518 (rank : 84)	NC score	0.026968 (rank : 26)
Query Neighborhood Hits	119	Target Neighborhood Hits	1582	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

OSBL5_HUMAN
θ value	5.27518 (rank : 85)	NC score	0.005311 (rank : 105)
Query Neighborhood Hits	119	Target Neighborhood Hits	117	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H0X9, Q9BZB0, Q9P1Z4	Gene names	OSBPL5, KIAA1534, ORP5
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5).

OXRP_HUMAN
θ value	5.27518 (rank : 86)	NC score	0.011158 (rank : 76)
Query Neighborhood Hits	119	Target Neighborhood Hits	544	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

RIN3_MOUSE
θ value	5.27518 (rank : 87)	NC score	0.010537 (rank : 80)
Query Neighborhood Hits	119	Target Neighborhood Hits	239	Shared Neighborhood Hits	20
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

TRI56_HUMAN
θ value	5.27518 (rank : 88)	NC score	0.006364 (rank : 98)
Query Neighborhood Hits	119	Target Neighborhood Hits	339	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

ATBF1_MOUSE
θ value	6.88961 (rank : 89)	NC score	0.002343 (rank : 114)
Query Neighborhood Hits	119	Target Neighborhood Hits	1841	Shared Neighborhood Hits	38
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

CNOT3_MOUSE
θ value	6.88961 (rank : 90)	NC score	0.013110 (rank : 69)
Query Neighborhood Hits	119	Target Neighborhood Hits	504	Shared Neighborhood Hits	29
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

MYST4_MOUSE
θ value	6.88961 (rank : 91)	NC score	0.007044 (rank : 95)
Query Neighborhood Hits	119	Target Neighborhood Hits	416	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

NPM_HUMAN
θ value	6.88961 (rank : 92)	NC score	0.018046 (rank : 49)
Query Neighborhood Hits	119	Target Neighborhood Hits	69	Shared Neighborhood Hits	10
SwissProt Accessions	P06748, P08693, Q12826, Q13440, Q13441, Q14115, Q5EU94, Q5EU95, Q5EU96, Q5EU97, Q5EU98, Q5EU99, Q6V962, Q8WTW5, Q96AT6, Q96DC4, Q96EA5	Gene names	NPM1, NPM
Domain Architecture
Description	Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Numatrin) (Nucleolar protein NO38).

PDE4D_HUMAN
θ value	6.88961 (rank : 93)	NC score	0.003635 (rank : 108)
Query Neighborhood Hits	119	Target Neighborhood Hits	122	Shared Neighborhood Hits	6
SwissProt Accessions	Q08499, O43433, Q13549, Q13550, Q13551, Q7Z2L8, Q8IV84, Q8IVA9, Q8IVD2, Q8IVD3, Q9HCX7	Gene names	PDE4D
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4D (EC 3.1.4.17) (DPDE3) (PDE43).

P_MOUSE
θ value	6.88961 (rank : 94)	NC score	0.027115 (rank : 25)
Query Neighborhood Hits	119	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	Q62052	Gene names	Oca2, P
Domain Architecture	No domain graphic available
Description	P protein (Melanocyte-specific transporter protein) (Pink-eyed dilution protein).

RFFL_HUMAN
θ value	6.88961 (rank : 95)	NC score	0.005544 (rank : 102)
Query Neighborhood Hits	119	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

SEN34_MOUSE
θ value	6.88961 (rank : 96)	NC score	0.008789 (rank : 88)
Query Neighborhood Hits	119	Target Neighborhood Hits	158	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BMZ5, Q58EU2, Q99LV6, Q9CYW1	Gene names	Tsen34, Leng5, Sen34
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (tRNA-intron endonuclease Sen34) (Leukocyte receptor cluster member 5 homolog).

SNIP_MOUSE
θ value	6.88961 (rank : 97)	NC score	0.015983 (rank : 54)
Query Neighborhood Hits	119	Target Neighborhood Hits	319	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QWI6, O70298	Gene names	P140, Kiaa1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

TINF2_MOUSE
θ value	6.88961 (rank : 98)	NC score	0.009456 (rank : 85)
Query Neighborhood Hits	119	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QXG9	Gene names	Tinf2, Tin2
Domain Architecture	No domain graphic available
Description	TERF1-interacting nuclear factor 2 (TRF1-interacting nuclear protein 2).

ZIM10_MOUSE
θ value	6.88961 (rank : 99)	NC score	0.010932 (rank : 78)
Query Neighborhood Hits	119	Target Neighborhood Hits	430	Shared Neighborhood Hits	29
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

A4_HUMAN
θ value	8.99809 (rank : 100)	NC score	0.003194 (rank : 109)
Query Neighborhood Hits	119	Target Neighborhood Hits	274	Shared Neighborhood Hits	4
SwissProt Accessions	P05067, P09000, P78438, Q13764, Q13778, Q13793, Q16011, Q16014, Q16019, Q16020, Q9BT38, Q9UCA9, Q9UCB6, Q9UCC8, Q9UCD1, Q9UQ58	Gene names	APP, A4, AD1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein) (Cerebral vascular amyloid peptide) (CVAP) (Protease nexin-II) (PN-II) (APPI) (PreA4) [Contains: Soluble APP-alpha (S-APP- alpha); Soluble APP-beta (S-APP-beta); C99; Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)); Gamma-CTF(57) (Gamma- secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

ABL1_HUMAN
θ value	8.99809 (rank : 101)	NC score	-0.002022 (rank : 120)
Query Neighborhood Hits	119	Target Neighborhood Hits	1220	Shared Neighborhood Hits	21
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

CO3A1_HUMAN
θ value	8.99809 (rank : 102)	NC score	0.008024 (rank : 89)
Query Neighborhood Hits	119	Target Neighborhood Hits	452	Shared Neighborhood Hits	25
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CO3A1_MOUSE
θ value	8.99809 (rank : 103)	NC score	0.007973 (rank : 90)
Query Neighborhood Hits	119	Target Neighborhood Hits	466	Shared Neighborhood Hits	27
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CO5A2_HUMAN
θ value	8.99809 (rank : 104)	NC score	0.005406 (rank : 104)
Query Neighborhood Hits	119	Target Neighborhood Hits	760	Shared Neighborhood Hits	30
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

CRTC1_MOUSE
θ value	8.99809 (rank : 105)	NC score	0.010268 (rank : 81)
Query Neighborhood Hits	119	Target Neighborhood Hits	230	Shared Neighborhood Hits	15
SwissProt Accessions	Q68ED7, Q6ZQ85	Gene names	Crtc1, Kiaa0616, Mect1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1 homolog).

FYB_HUMAN
θ value	8.99809 (rank : 106)	NC score	0.016165 (rank : 53)
Query Neighborhood Hits	119	Target Neighborhood Hits	379	Shared Neighborhood Hits	31
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

GOGA5_HUMAN
θ value	8.99809 (rank : 107)	NC score	0.002667 (rank : 111)
Query Neighborhood Hits	119	Target Neighborhood Hits	1168	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

GOGA5_MOUSE
θ value	8.99809 (rank : 108)	NC score	0.002528 (rank : 113)
Query Neighborhood Hits	119	Target Neighborhood Hits	1434	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

HECD2_MOUSE
θ value	8.99809 (rank : 109)	NC score	0.002322 (rank : 115)
Query Neighborhood Hits	119	Target Neighborhood Hits	38	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CDU6, Q8CBQ9	Gene names	Hectd2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

IQEC1_MOUSE
θ value	8.99809 (rank : 110)	NC score	0.002752 (rank : 110)
Query Neighborhood Hits	119	Target Neighborhood Hits	54	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R0S2, Q3TZC3, Q5DU15	Gene names	Iqsec1, Kiaa0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1.

KI67_HUMAN
θ value	8.99809 (rank : 111)	NC score	0.014279 (rank : 62)
Query Neighborhood Hits	119	Target Neighborhood Hits	581	Shared Neighborhood Hits	23
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

MAP1A_HUMAN
θ value	8.99809 (rank : 112)	NC score	0.009444 (rank : 86)
Query Neighborhood Hits	119	Target Neighborhood Hits	1626	Shared Neighborhood Hits	43
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

NBL1_MOUSE
θ value	8.99809 (rank : 113)	NC score	0.007651 (rank : 93)
Query Neighborhood Hits	119	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q61477	Gene names	Nbl1, Dan, Dana
Domain Architecture
Description	Neuroblastoma suppressor of tumorigenicity 1 precursor (Zinc finger protein DAN) (N03).

PHLB1_MOUSE
θ value	8.99809 (rank : 114)	NC score	0.014226 (rank : 63)
Query Neighborhood Hits	119	Target Neighborhood Hits	678	Shared Neighborhood Hits	23
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PXK_MOUSE
θ value	8.99809 (rank : 115)	NC score	0.005942 (rank : 101)
Query Neighborhood Hits	119	Target Neighborhood Hits	320	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BX57, Q3TD60, Q3TEL7, Q3TZZ1, Q3U197, Q3U773, Q3UCS5, Q4FBH7, Q91WB6	Gene names	Pxk
Domain Architecture	No domain graphic available
Description	PX domain-containing protein kinase-like protein (Modulator of Na,K- ATPase) (MONaKA).

SELPL_MOUSE
θ value	8.99809 (rank : 116)	NC score	0.011686 (rank : 73)
Query Neighborhood Hits	119	Target Neighborhood Hits	588	Shared Neighborhood Hits	25
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SEN2_MOUSE
θ value	8.99809 (rank : 117)	NC score	0.007665 (rank : 92)
Query Neighborhood Hits	119	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P7W5, Q3UYG6	Gene names	Tsen2, Sen2
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen2 (EC 3.1.27.9) (tRNA-intron endonuclease Sen2).

SON_HUMAN
θ value	8.99809 (rank : 118)	NC score	0.011173 (rank : 75)
Query Neighborhood Hits	119	Target Neighborhood Hits	1568	Shared Neighborhood Hits	50
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

ZIM10_HUMAN
θ value	8.99809 (rank : 119)	NC score	0.009616 (rank : 84)
Query Neighborhood Hits	119	Target Neighborhood Hits	577	Shared Neighborhood Hits	29
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

VMAT1_MOUSE
θ value	θ > 10 (rank : 120)	NC score	0.052578 (rank : 15)
Query Neighborhood Hits	119	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R090	Gene names	Slc18a1, Vmat1
Domain Architecture
Description	Chromaffin granule amine transporter (Vesicular amine transporter 1) (VAT1) (Solute carrier family 18 member 1).

Hits sorted by NC score

B3A3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	119	Target Neighborhood Hits	119	Shared Neighborhood Hits	119
SwissProt Accessions	P48751	Gene names	SLC4A3, AE3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3) (Cardiac/brain band 3-like protein) (CAE3/BAE3).

B3A3_MOUSE
NC score	0.993637 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	119	Target Neighborhood Hits	112	Shared Neighborhood Hits	59
SwissProt Accessions	P16283	Gene names	Slc4a3, Ae3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3).

B3A2_HUMAN
NC score	0.986841 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	119	Target Neighborhood Hits	57	Shared Neighborhood Hits	19
SwissProt Accessions	P04920, Q45EY5, Q969L3	Gene names	SLC4A2, AE2, EPB3L1, HKB3, MPB3L
Domain Architecture
Description	Anion exchange protein 2 (Non-erythroid band 3-like protein) (AE2 anion exchanger) (Solute carrier family 4 member 2) (BND3L).

B3A2_MOUSE
NC score	0.986343 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	119	Target Neighborhood Hits	64	Shared Neighborhood Hits	18
SwissProt Accessions	P13808, Q9ES09, Q9ES10, Q9ES11, Q9ES12, Q9ES13	Gene names	Slc4a2, Ae2
Domain Architecture
Description	Anion exchange protein 2 (Non-erythroid band 3-like protein) (AE2 anion exchanger) (Solute carrier family 4 member 2) (B3RP).

B3AT_HUMAN
NC score	0.985394 (rank : 5)	θ value	0 (rank : 5)
Query Neighborhood Hits	119	Target Neighborhood Hits	31	Shared Neighborhood Hits	15
SwissProt Accessions	P02730, P78487, Q4VB84	Gene names	SLC4A1, AE1, DI, EPB3
Domain Architecture
Description	Band 3 anion transport protein (Anion exchange protein 1) (AE 1) (Solute carrier family 4 member 1) (CD233 antigen).

B3AT_MOUSE
NC score	0.984730 (rank : 6)	θ value	0 (rank : 6)
Query Neighborhood Hits	119	Target Neighborhood Hits	23	Shared Neighborhood Hits	14
SwissProt Accessions	P04919	Gene names	Slc4a1, Ae1
Domain Architecture
Description	Band 3 anion transport protein (Anion exchange protein 1) (AE 1) (Solute carrier family 4 member 1) (MEB3) (CD233 antigen).

S4A4_HUMAN
NC score	0.969625 (rank : 7)	θ value	4.23373e-183 (rank : 8)
Query Neighborhood Hits	119	Target Neighborhood Hits	33	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y6R1, O15153, Q8NEJ2, Q9H262, Q9NRZ1, Q9UIC0, Q9UIC1, Q9UP50	Gene names	SLC4A4, NBC, NBC1, NBCE1
Domain Architecture	No domain graphic available
Description	Electrogenic sodium bicarbonate cotransporter 1 (Sodium bicarbonate cotransporter) (Na(+)/HCO3(-) cotransporter) (Solute carrier family 4 member 4) (kNBC1).

S4A4_MOUSE
NC score	0.969217 (rank : 8)	θ value	7.22167e-183 (rank : 9)
Query Neighborhood Hits	119	Target Neighborhood Hits	31	Shared Neighborhood Hits	14
SwissProt Accessions	O88343, Q3USE4, Q8BUG0, Q8QZR9, Q9R1C4	Gene names	Slc4a4, Nbc1, Nbce1
Domain Architecture	No domain graphic available
Description	Electrogenic sodium bicarbonate cotransporter 1 (Sodium bicarbonate cotransporter) (Na(+)/HCO3(-) cotransporter) (Solute carrier family 4 member 4).

B3A4_HUMAN
NC score	0.967903 (rank : 9)	θ value	1.09172e-138 (rank : 12)
Query Neighborhood Hits	119	Target Neighborhood Hits	28	Shared Neighborhood Hits	14
SwissProt Accessions	Q96Q91, Q96RM5, Q9BXF2, Q9BXN3	Gene names	SLC4A9, AE4, SBC5
Domain Architecture
Description	Anion exchange protein 4 (Anion exchanger 4) (Solute carrier family 4 member 9) (Sodium bicarbonate cotransporter 5).

S4A10_HUMAN
NC score	0.967026 (rank : 10)	θ value	0 (rank : 7)
Query Neighborhood Hits	119	Target Neighborhood Hits	33	Shared Neighborhood Hits	15
SwissProt Accessions	Q6U841, Q4ZFX6, Q8TCP2, Q9HCQ6	Gene names	SLC4A10, NCBE
Domain Architecture	No domain graphic available
Description	Sodium-driven chloride bicarbonate exchanger (Solute carrier family 4 member 10).

S4A10_MOUSE
NC score	0.966362 (rank : 11)	θ value	1.07914e-178 (rank : 10)
Query Neighborhood Hits	119	Target Neighborhood Hits	23	Shared Neighborhood Hits	14
SwissProt Accessions	Q5DTL9, Q8CFS3, Q9EST0	Gene names	Slc4a10, Kiaa4136, Ncbe
Domain Architecture	No domain graphic available
Description	Sodium-driven chloride bicarbonate exchanger (Solute carrier family 4 member 10).

S4A7_HUMAN
NC score	0.961967 (rank : 12)	θ value	1.42253e-146 (rank : 11)
Query Neighborhood Hits	119	Target Neighborhood Hits	55	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y6M7, O60350, Q6AHZ9, Q9HC88, Q9UIB9	Gene names	SLC4A7, BT, NBC2, NBC2B, NBC3, SBC2, SLC4A6
Domain Architecture	No domain graphic available
Description	Sodium bicarbonate cotransporter 3 (Sodium bicarbonate cotransporter 2) (Sodium bicarbonate cotransporter 2b) (Bicarbonate transporter) (Solute carrier family 4 member 7).

S4A7_MOUSE
NC score	0.956527 (rank : 13)	θ value	6.43005e-123 (rank : 13)
Query Neighborhood Hits	119	Target Neighborhood Hits	30	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BTY2, Q3U5H7	Gene names	Slc4a7, Nbc3
Domain Architecture	No domain graphic available
Description	Sodium bicarbonate cotransporter 3 (Solute carrier family 4 member 7).

S4A11_HUMAN
NC score	0.915941 (rank : 14)	θ value	1.36902e-48 (rank : 14)
Query Neighborhood Hits	119	Target Neighborhood Hits	23	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NBS3, Q9BXF4, Q9NTW9	Gene names	SLC4A11, BTR1
Domain Architecture
Description	Sodium bicarbonate transporter-like protein 11 (Bicarbonate transporter-related protein 1) (Solute carrier family 4 member 11).

VMAT1_MOUSE
NC score	0.052578 (rank : 15)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	119	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R090	Gene names	Slc18a1, Vmat1
Domain Architecture
Description	Chromaffin granule amine transporter (Vesicular amine transporter 1) (VAT1) (Solute carrier family 18 member 1).

ERCC1_HUMAN
NC score	0.041065 (rank : 16)	θ value	0.279714 (rank : 22)
Query Neighborhood Hits	119	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	P07992	Gene names	ERCC1
Domain Architecture
Description	DNA excision repair protein ERCC-1.

NIPBL_HUMAN
NC score	0.038108 (rank : 17)	θ value	0.000786445 (rank : 15)
Query Neighborhood Hits	119	Target Neighborhood Hits	1311	Shared Neighborhood Hits	40
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

PHAR3_MOUSE
NC score	0.037380 (rank : 18)	θ value	0.0148317 (rank : 18)
Query Neighborhood Hits	119	Target Neighborhood Hits	206	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BYK5, Q8BYS8, Q8C058, Q9DB87	Gene names	Phactr3, Scapin1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 3 (Scapinin) (Scaffold-associated PP1- inhibiting protein).

OGFR_MOUSE
NC score	0.035627 (rank : 19)	θ value	0.00665767 (rank : 16)
Query Neighborhood Hits	119	Target Neighborhood Hits	584	Shared Neighborhood Hits	28
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

CASC3_MOUSE
NC score	0.031908 (rank : 20)	θ value	0.47712 (rank : 26)
Query Neighborhood Hits	119	Target Neighborhood Hits	333	Shared Neighborhood Hits	21
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

MA1B1_HUMAN
NC score	0.030534 (rank : 21)	θ value	0.0961366 (rank : 21)
Query Neighborhood Hits	119	Target Neighborhood Hits	125	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UKM7, Q5VSG3, Q9BRS9, Q9Y5K7	Gene names	MAN1B1
Domain Architecture
Description	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (Mannosidase alpha class 1B member 1) (Man9GlcNAc2-specific-processing alpha-mannosidase).

TENS1_HUMAN
NC score	0.029486 (rank : 22)	θ value	0.0736092 (rank : 20)
Query Neighborhood Hits	119	Target Neighborhood Hits	400	Shared Neighborhood Hits	25
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

MDC1_MOUSE
NC score	0.029182 (rank : 23)	θ value	0.365318 (rank : 25)
Query Neighborhood Hits	119	Target Neighborhood Hits	998	Shared Neighborhood Hits	46
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

NPBL_MOUSE
NC score	0.027491 (rank : 24)	θ value	2.36792 (rank : 54)
Query Neighborhood Hits	119	Target Neighborhood Hits	1041	Shared Neighborhood Hits	32
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

P_MOUSE
NC score	0.027115 (rank : 25)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	119	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	Q62052	Gene names	Oca2, P
Domain Architecture	No domain graphic available
Description	P protein (Melanocyte-specific transporter protein) (Pink-eyed dilution protein).

OGFR_HUMAN
NC score	0.026968 (rank : 26)	θ value	5.27518 (rank : 84)
Query Neighborhood Hits	119	Target Neighborhood Hits	1582	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

TXND2_HUMAN
NC score	0.026128 (rank : 27)	θ value	0.62314 (rank : 33)
Query Neighborhood Hits	119	Target Neighborhood Hits	793	Shared Neighborhood Hits	36
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

CO002_HUMAN
NC score	0.025422 (rank : 28)	θ value	1.38821 (rank : 39)
Query Neighborhood Hits	119	Target Neighborhood Hits	387	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

MAP9_MOUSE
NC score	0.024278 (rank : 29)	θ value	0.62314 (rank : 32)
Query Neighborhood Hits	119	Target Neighborhood Hits	529	Shared Neighborhood Hits	12
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

I28RA_HUMAN
NC score	0.024188 (rank : 30)	θ value	2.36792 (rank : 52)
Query Neighborhood Hits	119	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IU57, Q6ZML8, Q8IZI7, Q8IZI8	Gene names	IL28RA, IFNLR1, LICR2
Domain Architecture	No domain graphic available
Description	Interleukin-28 receptor alpha chain precursor (IL-28R-alpha) (IL-28RA) (Cytokine receptor family 2 member 12) (Cytokine receptor class-II member 12) (CRF2-12) (Interferon lambda receptor 1) (IFN-lambda R1) (Likely interleukin or cytokine receptor 2).

SNPC2_MOUSE
NC score	0.024074 (rank : 31)	θ value	1.81305 (rank : 45)
Query Neighborhood Hits	119	Target Neighborhood Hits	83	Shared Neighborhood Hits	6
SwissProt Accessions	Q91XA5, Q3UK17, Q8CBS9	Gene names	Snapc2
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 2 (SNAPc subunit 2) (snRNA- activating protein complex 45 kDa subunit) (SNAPc 45 kDa subunit) (Small nuclear RNA-activating complex polypeptide 2).

BCAS1_MOUSE
NC score	0.023456 (rank : 32)	θ value	2.36792 (rank : 49)
Query Neighborhood Hits	119	Target Neighborhood Hits	215	Shared Neighborhood Hits	20
SwissProt Accessions	Q80YN3, Q9CVA1	Gene names	Bcas1, Nabc1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 1 homolog (Novel amplified in breast cancer 1 homolog).

MBB1A_HUMAN
NC score	0.023255 (rank : 33)	θ value	2.36792 (rank : 53)
Query Neighborhood Hits	119	Target Neighborhood Hits	665	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

FRS3_MOUSE
NC score	0.022972 (rank : 34)	θ value	3.0926 (rank : 60)
Query Neighborhood Hits	119	Target Neighborhood Hits	168	Shared Neighborhood Hits	10
SwissProt Accessions	Q91WJ0	Gene names	Frs3, Frs2b
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (FRS2-beta).

PO121_MOUSE
NC score	0.022622 (rank : 35)	θ value	3.0926 (rank : 61)
Query Neighborhood Hits	119	Target Neighborhood Hits	345	Shared Neighborhood Hits	24
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

CT151_HUMAN
NC score	0.021357 (rank : 36)	θ value	2.36792 (rank : 50)
Query Neighborhood Hits	119	Target Neighborhood Hits	382	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

NFH_MOUSE
NC score	0.021355 (rank : 37)	θ value	0.0193708 (rank : 19)
Query Neighborhood Hits	119	Target Neighborhood Hits	2247	Shared Neighborhood Hits	63
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

GTSE1_HUMAN
NC score	0.021065 (rank : 38)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	119	Target Neighborhood Hits	193	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NYZ3, Q53GX5, Q5R3I6, Q6DHX4, Q9BRE0, Q9UGZ9, Q9Y557	Gene names	GTSE1
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (B99 homolog).

CCDC8_HUMAN
NC score	0.020947 (rank : 39)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	119	Target Neighborhood Hits	70	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H0W5, Q8TB26	Gene names	CCDC8
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 8.

DVL3_HUMAN
NC score	0.020459 (rank : 40)	θ value	0.365318 (rank : 24)
Query Neighborhood Hits	119	Target Neighborhood Hits	194	Shared Neighborhood Hits	8
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

BTBD7_HUMAN
NC score	0.020447 (rank : 41)	θ value	0.62314 (rank : 30)
Query Neighborhood Hits	119	Target Neighborhood Hits	176	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P203, Q69Z05, Q7Z308, Q86TS0, Q9HAA4, Q9NVM0	Gene names	BTBD7, KIAA1525
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 7.

NPM_MOUSE
NC score	0.019205 (rank : 42)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	119	Target Neighborhood Hits	69	Shared Neighborhood Hits	9
SwissProt Accessions	Q61937	Gene names	Npm1
Domain Architecture
Description	Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Numatrin) (Nucleolar protein NO38).

MLL2_HUMAN
NC score	0.019190 (rank : 43)	θ value	1.81305 (rank : 43)
Query Neighborhood Hits	119	Target Neighborhood Hits	1788	Shared Neighborhood Hits	56
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MYBB_MOUSE
NC score	0.019176 (rank : 44)	θ value	1.06291 (rank : 36)
Query Neighborhood Hits	119	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	P48972	Gene names	Mybl2, Bmyb
Domain Architecture
Description	Myb-related protein B (B-Myb).

SLIK3_MOUSE
NC score	0.019006 (rank : 45)	θ value	0.0113563 (rank : 17)
Query Neighborhood Hits	119	Target Neighborhood Hits	308	Shared Neighborhood Hits	4
SwissProt Accessions	Q810B9	Gene names	Slitrk3
Domain Architecture
Description	SLIT and NTRK-like protein 3 precursor.

NTKL_MOUSE
NC score	0.018727 (rank : 46)	θ value	0.279714 (rank : 23)
Query Neighborhood Hits	119	Target Neighborhood Hits	326	Shared Neighborhood Hits	6
SwissProt Accessions	Q9EQC5, Q3TST7, Q3UKU0, Q8K222	Gene names	Scyl1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like protein (SCY1-like protein 1) (105 kDa kinase- like protein) (Mitosis-associated kinase-like protein NTKL).

ETV3_HUMAN
NC score	0.018575 (rank : 47)	θ value	0.62314 (rank : 31)
Query Neighborhood Hits	119	Target Neighborhood Hits	312	Shared Neighborhood Hits	17
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

ADDB_MOUSE
NC score	0.018063 (rank : 48)	θ value	2.36792 (rank : 48)
Query Neighborhood Hits	119	Target Neighborhood Hits	574	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

NPM_HUMAN
NC score	0.018046 (rank : 49)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	119	Target Neighborhood Hits	69	Shared Neighborhood Hits	10
SwissProt Accessions	P06748, P08693, Q12826, Q13440, Q13441, Q14115, Q5EU94, Q5EU95, Q5EU96, Q5EU97, Q5EU98, Q5EU99, Q6V962, Q8WTW5, Q96AT6, Q96DC4, Q96EA5	Gene names	NPM1, NPM
Domain Architecture
Description	Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Numatrin) (Nucleolar protein NO38).

NACAM_MOUSE
NC score	0.017510 (rank : 50)	θ value	0.813845 (rank : 34)
Query Neighborhood Hits	119	Target Neighborhood Hits	1866	Shared Neighborhood Hits	55
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NTKL_HUMAN
NC score	0.017269 (rank : 51)	θ value	2.36792 (rank : 55)
Query Neighborhood Hits	119	Target Neighborhood Hits	266	Shared Neighborhood Hits	6
SwissProt Accessions	Q96KG9, Q96G50, Q96KG8, Q96KH1, Q9HAW5, Q9HBL3, Q9NR53	Gene names	SCYL1, GKLP, NTKL, TAPK, TEIF, TRAP
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like protein (SCY1-like protein 1) (Teratoma- associated tyrosine kinase) (Telomerase transcriptional element- interacting factor) (Telomerase regulation-associated protein).

PCLO_HUMAN
NC score	0.016633 (rank : 52)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	119	Target Neighborhood Hits	2046	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

FYB_HUMAN
NC score	0.016165 (rank : 53)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	119	Target Neighborhood Hits	379	Shared Neighborhood Hits	31
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

SNIP_MOUSE
NC score	0.015983 (rank : 54)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	119	Target Neighborhood Hits	319	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QWI6, O70298	Gene names	P140, Kiaa1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

PHLB1_HUMAN
NC score	0.015931 (rank : 55)	θ value	0.47712 (rank : 27)
Query Neighborhood Hits	119	Target Neighborhood Hits	1038	Shared Neighborhood Hits	31
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

TNFL6_MOUSE
NC score	0.015756 (rank : 56)	θ value	3.0926 (rank : 62)
Query Neighborhood Hits	119	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	P41047, Q61217, Q9R1F2	Gene names	Faslg, Apt1lg1, Fasl, gld, Tnfsf6
Domain Architecture
Description	Tumor necrosis factor ligand superfamily member 6 (Fas antigen ligand) (Fas ligand) (CD178 antigen) (CD95L protein) [Contains: Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form].

LCP2_HUMAN
NC score	0.015645 (rank : 57)	θ value	1.38821 (rank : 41)
Query Neighborhood Hits	119	Target Neighborhood Hits	531	Shared Neighborhood Hits	23
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

DAZP2_MOUSE
NC score	0.015068 (rank : 58)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	119	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DCP9, O88675, Q3UVI4	Gene names	Dazap2, Prtb
Domain Architecture	No domain graphic available
Description	DAZ-associated protein 2 (Deleted in azoospermia-associated protein 2) (Proline-rich protein expressed in brain).

K1802_MOUSE
NC score	0.015025 (rank : 59)	θ value	1.06291 (rank : 35)
Query Neighborhood Hits	119	Target Neighborhood Hits	1596	Shared Neighborhood Hits	41
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MKL1_MOUSE
NC score	0.014867 (rank : 60)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	119	Target Neighborhood Hits	667	Shared Neighborhood Hits	28
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

NCOR2_MOUSE
NC score	0.014819 (rank : 61)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	119	Target Neighborhood Hits	790	Shared Neighborhood Hits	41
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

KI67_HUMAN
NC score	0.014279 (rank : 62)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	119	Target Neighborhood Hits	581	Shared Neighborhood Hits	23
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

PHLB1_MOUSE
NC score	0.014226 (rank : 63)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	119	Target Neighborhood Hits	678	Shared Neighborhood Hits	23
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

DVL3_MOUSE
NC score	0.014064 (rank : 64)	θ value	1.38821 (rank : 40)
Query Neighborhood Hits	119	Target Neighborhood Hits	198	Shared Neighborhood Hits	5
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

REV1_MOUSE
NC score	0.014048 (rank : 65)	θ value	1.81305 (rank : 44)
Query Neighborhood Hits	119	Target Neighborhood Hits	67	Shared Neighborhood Hits	6
SwissProt Accessions	Q920Q2, Q9QXV2	Gene names	Rev1l, Rev1
Domain Architecture	No domain graphic available
Description	DNA repair protein REV1 (EC 2.7.7.-) (Rev1-like terminal deoxycytidyl transferase).

TCAL5_HUMAN
NC score	0.013822 (rank : 66)	θ value	1.81305 (rank : 46)
Query Neighborhood Hits	119	Target Neighborhood Hits	806	Shared Neighborhood Hits	24
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

LSP1_HUMAN
NC score	0.013334 (rank : 67)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	119	Target Neighborhood Hits	142	Shared Neighborhood Hits	6
SwissProt Accessions	P33241, Q16096, Q9BUY8	Gene names	LSP1, WP34
Domain Architecture	No domain graphic available
Description	Lymphocyte-specific protein 1 (Protein pp52) (52 kDa phosphoprotein) (Lymphocyte-specific antigen WP34) (47 kDa actin-binding protein).

SC24C_HUMAN
NC score	0.013158 (rank : 68)	θ value	2.36792 (rank : 56)
Query Neighborhood Hits	119	Target Neighborhood Hits	662	Shared Neighborhood Hits	33
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

CNOT3_MOUSE
NC score	0.013110 (rank : 69)	θ value	6.88961 (rank : 90)
Query Neighborhood Hits	119	Target Neighborhood Hits	504	Shared Neighborhood Hits	29
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CTDP1_HUMAN
NC score	0.012567 (rank : 70)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	119	Target Neighborhood Hits	416	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

DOCK8_HUMAN
NC score	0.012508 (rank : 71)	θ value	3.0926 (rank : 59)
Query Neighborhood Hits	119	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NF50, Q3MV16, Q5JPJ1, Q8TEP1, Q8WUY2, Q9BYJ5, Q9H1Q2, Q9H1Q3, Q9H308, Q9H7P2	Gene names	DOCK8
Domain Architecture	No domain graphic available
Description	Dedicator of cytokinesis protein 8.

ZN638_MOUSE
NC score	0.012154 (rank : 72)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	119	Target Neighborhood Hits	318	Shared Neighborhood Hits	9
SwissProt Accessions	Q61464, Q6DFV9, Q8C941	Gene names	Znf638, Np220, Zfml
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein).

SELPL_MOUSE
NC score	0.011686 (rank : 73)	θ value	8.99809 (rank : 116)
Query Neighborhood Hits	119	Target Neighborhood Hits	588	Shared Neighborhood Hits	25
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SLIK3_HUMAN
NC score	0.011176 (rank : 74)	θ value	1.06291 (rank : 37)
Query Neighborhood Hits	119	Target Neighborhood Hits	298	Shared Neighborhood Hits	5
SwissProt Accessions	O94933	Gene names	SLITRK3, KIAA0848
Domain Architecture	No domain graphic available
Description	SLIT and NTRK-like protein 3 precursor.

SON_HUMAN
NC score	0.011173 (rank : 75)	θ value	8.99809 (rank : 118)
Query Neighborhood Hits	119	Target Neighborhood Hits	1568	Shared Neighborhood Hits	50
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

OXRP_HUMAN
NC score	0.011158 (rank : 76)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	119	Target Neighborhood Hits	544	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

SMC4_MOUSE
NC score	0.011015 (rank : 77)	θ value	0.47712 (rank : 28)
Query Neighborhood Hits	119	Target Neighborhood Hits	830	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

ZIM10_MOUSE
NC score	0.010932 (rank : 78)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	119	Target Neighborhood Hits	430	Shared Neighborhood Hits	29
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

DCBD2_MOUSE
NC score	0.010788 (rank : 79)	θ value	1.81305 (rank : 42)
Query Neighborhood Hits	119	Target Neighborhood Hits	113	Shared Neighborhood Hits	4
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

RIN3_MOUSE
NC score	0.010537 (rank : 80)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	119	Target Neighborhood Hits	239	Shared Neighborhood Hits	20
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

CRTC1_MOUSE
NC score	0.010268 (rank : 81)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	119	Target Neighborhood Hits	230	Shared Neighborhood Hits	15
SwissProt Accessions	Q68ED7, Q6ZQ85	Gene names	Crtc1, Kiaa0616, Mect1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1 homolog).

HCN4_HUMAN
NC score	0.009960 (rank : 82)	θ value	2.36792 (rank : 51)
Query Neighborhood Hits	119	Target Neighborhood Hits	303	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HCN4_MOUSE
NC score	0.009729 (rank : 83)	θ value	4.03905 (rank : 69)
Query Neighborhood Hits	119	Target Neighborhood Hits	284	Shared Neighborhood Hits	19
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

ZIM10_HUMAN
NC score	0.009616 (rank : 84)	θ value	8.99809 (rank : 119)
Query Neighborhood Hits	119	Target Neighborhood Hits	577	Shared Neighborhood Hits	29
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

TINF2_MOUSE
NC score	0.009456 (rank : 85)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	119	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QXG9	Gene names	Tinf2, Tin2
Domain Architecture	No domain graphic available
Description	TERF1-interacting nuclear factor 2 (TRF1-interacting nuclear protein 2).

MAP1A_HUMAN
NC score	0.009444 (rank : 86)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	119	Target Neighborhood Hits	1626	Shared Neighborhood Hits	43
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

EMID1_MOUSE
NC score	0.009088 (rank : 87)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	119	Target Neighborhood Hits	230	Shared Neighborhood Hits	18
SwissProt Accessions	Q91VF5	Gene names	Emid1, Emu1
Domain Architecture	No domain graphic available
Description	EMI domain-containing protein 1 precursor (Protein Emu1) (Emilin and multimerin domain-containing protein 1).

SEN34_MOUSE
NC score	0.008789 (rank : 88)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	119	Target Neighborhood Hits	158	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BMZ5, Q58EU2, Q99LV6, Q9CYW1	Gene names	Tsen34, Leng5, Sen34
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (tRNA-intron endonuclease Sen34) (Leukocyte receptor cluster member 5 homolog).

CO3A1_HUMAN
NC score	0.008024 (rank : 89)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	119	Target Neighborhood Hits	452	Shared Neighborhood Hits	25
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CO3A1_MOUSE
NC score	0.007973 (rank : 90)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	119	Target Neighborhood Hits	466	Shared Neighborhood Hits	27
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

BCR_HUMAN
NC score	0.007752 (rank : 91)	θ value	5.27518 (rank : 75)
Query Neighborhood Hits	119	Target Neighborhood Hits	204	Shared Neighborhood Hits	10
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

SEN2_MOUSE
NC score	0.007665 (rank : 92)	θ value	8.99809 (rank : 117)
Query Neighborhood Hits	119	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P7W5, Q3UYG6	Gene names	Tsen2, Sen2
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen2 (EC 3.1.27.9) (tRNA-intron endonuclease Sen2).

NBL1_MOUSE
NC score	0.007651 (rank : 93)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	119	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q61477	Gene names	Nbl1, Dan, Dana
Domain Architecture
Description	Neuroblastoma suppressor of tumorigenicity 1 precursor (Zinc finger protein DAN) (N03).

KCNH6_HUMAN
NC score	0.007064 (rank : 94)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	119	Target Neighborhood Hits	222	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

MYST4_MOUSE
NC score	0.007044 (rank : 95)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	119	Target Neighborhood Hits	416	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

DNMBP_MOUSE
NC score	0.006934 (rank : 96)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	119	Target Neighborhood Hits	435	Shared Neighborhood Hits	12
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

SMAD9_MOUSE
NC score	0.006731 (rank : 97)	θ value	2.36792 (rank : 57)
Query Neighborhood Hits	119	Target Neighborhood Hits	75	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JIW5, Q8CFF9	Gene names	Smad9, Madh8, Madh9, Smad8
Domain Architecture
Description	Mothers against decapentaplegic homolog 9 (SMAD 9) (Mothers against DPP homolog 9) (Smad9) (Smad8).

TRI56_HUMAN
NC score	0.006364 (rank : 98)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	119	Target Neighborhood Hits	339	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

C1QT6_HUMAN
NC score	0.006296 (rank : 99)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	119	Target Neighborhood Hits	122	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BXI9	Gene names	C1QTNF6, CTRP6
Domain Architecture
Description	Complement C1q tumor necrosis factor-related protein 6 precursor.

CSKI1_MOUSE
NC score	0.005962 (rank : 100)	θ value	4.03905 (rank : 66)
Query Neighborhood Hits	119	Target Neighborhood Hits	1031	Shared Neighborhood Hits	39
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

PXK_MOUSE
NC score	0.005942 (rank : 101)	θ value	8.99809 (rank : 115)
Query Neighborhood Hits	119	Target Neighborhood Hits	320	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BX57, Q3TD60, Q3TEL7, Q3TZZ1, Q3U197, Q3U773, Q3UCS5, Q4FBH7, Q91WB6	Gene names	Pxk
Domain Architecture	No domain graphic available
Description	PX domain-containing protein kinase-like protein (Modulator of Na,K- ATPase) (MONaKA).

RFFL_HUMAN
NC score	0.005544 (rank : 102)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	119	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

CLMN_HUMAN
NC score	0.005477 (rank : 103)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	119	Target Neighborhood Hits	205	Shared Neighborhood Hits	8
SwissProt Accessions	Q96JQ2, Q9H713, Q9HA23, Q9HA57, Q9UFP4, Q9ULN2	Gene names	CLMN, KIAA1188
Domain Architecture
Description	Calmin.

CO5A2_HUMAN
NC score	0.005406 (rank : 104)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	119	Target Neighborhood Hits	760	Shared Neighborhood Hits	30
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

OSBL5_HUMAN
NC score	0.005311 (rank : 105)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	119	Target Neighborhood Hits	117	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H0X9, Q9BZB0, Q9P1Z4	Gene names	OSBPL5, KIAA1534, ORP5
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5).

BT2A2_HUMAN
NC score	0.004279 (rank : 106)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	119	Target Neighborhood Hits	191	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WVV5, O00480	Gene names	BTN2A2, BT2.2, BTF2
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A2 precursor.

ANXA7_MOUSE
NC score	0.004270 (rank : 107)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	119	Target Neighborhood Hits	142	Shared Neighborhood Hits	7
SwissProt Accessions	Q07076	Gene names	Anxa7, Anx7
Domain Architecture
Description	Annexin A7 (Annexin VII) (Synexin).

PDE4D_HUMAN
NC score	0.003635 (rank : 108)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	119	Target Neighborhood Hits	122	Shared Neighborhood Hits	6
SwissProt Accessions	Q08499, O43433, Q13549, Q13550, Q13551, Q7Z2L8, Q8IV84, Q8IVA9, Q8IVD2, Q8IVD3, Q9HCX7	Gene names	PDE4D
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4D (EC 3.1.4.17) (DPDE3) (PDE43).

A4_HUMAN
NC score	0.003194 (rank : 109)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	119	Target Neighborhood Hits	274	Shared Neighborhood Hits	4
SwissProt Accessions	P05067, P09000, P78438, Q13764, Q13778, Q13793, Q16011, Q16014, Q16019, Q16020, Q9BT38, Q9UCA9, Q9UCB6, Q9UCC8, Q9UCD1, Q9UQ58	Gene names	APP, A4, AD1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein) (Cerebral vascular amyloid peptide) (CVAP) (Protease nexin-II) (PN-II) (APPI) (PreA4) [Contains: Soluble APP-alpha (S-APP- alpha); Soluble APP-beta (S-APP-beta); C99; Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)); Gamma-CTF(57) (Gamma- secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

IQEC1_MOUSE
NC score	0.002752 (rank : 110)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	119	Target Neighborhood Hits	54	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R0S2, Q3TZC3, Q5DU15	Gene names	Iqsec1, Kiaa0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1.

GOGA5_HUMAN
NC score	0.002667 (rank : 111)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	119	Target Neighborhood Hits	1168	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

SPEG_MOUSE
NC score	0.002588 (rank : 112)	θ value	1.06291 (rank : 38)
Query Neighborhood Hits	119	Target Neighborhood Hits	1959	Shared Neighborhood Hits	43
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

GOGA5_MOUSE
NC score	0.002528 (rank : 113)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	119	Target Neighborhood Hits	1434	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

ATBF1_MOUSE
NC score	0.002343 (rank : 114)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	119	Target Neighborhood Hits	1841	Shared Neighborhood Hits	38
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

HECD2_MOUSE
NC score	0.002322 (rank : 115)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	119	Target Neighborhood Hits	38	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CDU6, Q8CBQ9	Gene names	Hectd2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

MAST4_HUMAN
NC score	0.001339 (rank : 116)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	119	Target Neighborhood Hits	1804	Shared Neighborhood Hits	42
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

TLK2_HUMAN
NC score	0.000972 (rank : 117)	θ value	0.47712 (rank : 29)
Query Neighborhood Hits	119	Target Neighborhood Hits	1044	Shared Neighborhood Hits	12
SwissProt Accessions	Q86UE8, Q9UKI7, Q9Y4F7	Gene names	TLK2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2) (PKU-alpha).

ZIC5_HUMAN
NC score	-0.001265 (rank : 118)	θ value	2.36792 (rank : 58)
Query Neighborhood Hits	119	Target Neighborhood Hits	774	Shared Neighborhood Hits	12
SwissProt Accessions	Q96T25	Gene names	ZIC5
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZIC 5 (Zinc finger protein of the cerebellum 5).

ZN690_HUMAN
NC score	-0.002014 (rank : 119)	θ value	1.81305 (rank : 47)
Query Neighborhood Hits	119	Target Neighborhood Hits	777	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IWY8, Q32M75, Q32M76, Q8NA40	Gene names	ZNF690
Domain Architecture	No domain graphic available
Description	Zinc finger protein 690.

ABL1_HUMAN
NC score	-0.002022 (rank : 120)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	119	Target Neighborhood Hits	1220	Shared Neighborhood Hits	21
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).