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Network neighborhood for query Sequence : SYTL2_MOUSE

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SYTL2_MOUSE
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SYTL2_HUMAN
θ value	0 (rank : 1)	NC score	0.976074 (rank : 2)
Query Neighborhood Hits	253	Target Neighborhood Hits	248	Shared Neighborhood Hits	121
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

SYTL2_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	253	Target Neighborhood Hits	253	Shared Neighborhood Hits	253
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

SYTL1_HUMAN
θ value	3.22841e-82 (rank : 3)	NC score	0.931509 (rank : 3)
Query Neighborhood Hits	253	Target Neighborhood Hits	227	Shared Neighborhood Hits	108
SwissProt Accessions	Q8IYJ3, Q96BB6, Q96GU6, Q96S89, Q96SI0	Gene names	SYTL1, SLP1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1) (SB146).

SYTL1_MOUSE
θ value	5.15425e-80 (rank : 4)	NC score	0.919444 (rank : 6)
Query Neighborhood Hits	253	Target Neighborhood Hits	314	Shared Neighborhood Hits	109
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

SYTL4_MOUSE
θ value	3.45727e-76 (rank : 5)	NC score	0.923772 (rank : 5)
Query Neighborhood Hits	253	Target Neighborhood Hits	137	Shared Neighborhood Hits	101
SwissProt Accessions	Q9R0Q1, Q8R321, Q9R0Q0	Gene names	Sytl4, Slp4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

SYTL4_HUMAN
θ value	1.22964e-73 (rank : 6)	NC score	0.924191 (rank : 4)
Query Neighborhood Hits	253	Target Neighborhood Hits	138	Shared Neighborhood Hits	99
SwissProt Accessions	Q96C24, Q5H9J3, Q5JPG8, Q8N9P4, Q9H4R0, Q9H4R1	Gene names	SYTL4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

SYTL5_HUMAN
θ value	1.40689e-69 (rank : 7)	NC score	0.915316 (rank : 8)
Query Neighborhood Hits	253	Target Neighborhood Hits	237	Shared Neighborhood Hits	121
SwissProt Accessions	Q8TDW5	Gene names	SYTL5, SLP5
Domain Architecture
Description	Synaptotagmin-like protein 5.

SYTL5_MOUSE
θ value	1.07972e-61 (rank : 8)	NC score	0.916724 (rank : 7)
Query Neighborhood Hits	253	Target Neighborhood Hits	154	Shared Neighborhood Hits	105
SwissProt Accessions	Q80T23, Q812E5	Gene names	Sytl5, Slp5
Domain Architecture
Description	Synaptotagmin-like protein 5.

SYTL3_MOUSE
θ value	1.91031e-50 (rank : 9)	NC score	0.908288 (rank : 9)
Query Neighborhood Hits	253	Target Neighborhood Hits	110	Shared Neighborhood Hits	87
SwissProt Accessions	Q99N48, Q8C506, Q99N47, Q99N49, Q99N54, Q99N79	Gene names	Sytl3, Slp3
Domain Architecture
Description	Synaptotagmin-like protein 3 (Exophilin-6).

SYT3_HUMAN
θ value	5.23862e-24 (rank : 10)	NC score	0.794554 (rank : 11)
Query Neighborhood Hits	253	Target Neighborhood Hits	145	Shared Neighborhood Hits	105
SwissProt Accessions	Q9BQG1, Q8N5Z1, Q8N640	Gene names	SYT3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

SYT3_MOUSE
θ value	7.56453e-23 (rank : 11)	NC score	0.794179 (rank : 12)
Query Neighborhood Hits	253	Target Neighborhood Hits	147	Shared Neighborhood Hits	104
SwissProt Accessions	O35681, P97791, Q80WV1	Gene names	Syt3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

SYT6_MOUSE
θ value	2.20094e-22 (rank : 12)	NC score	0.781169 (rank : 20)
Query Neighborhood Hits	253	Target Neighborhood Hits	132	Shared Neighborhood Hits	102
SwissProt Accessions	Q9R0N8	Gene names	Syt6
Domain Architecture
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

SYT6_HUMAN
θ value	6.40375e-22 (rank : 13)	NC score	0.780223 (rank : 25)
Query Neighborhood Hits	253	Target Neighborhood Hits	138	Shared Neighborhood Hits	102
SwissProt Accessions	Q5T7P8	Gene names	SYT6
Domain Architecture	No domain graphic available
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

DOC2B_MOUSE
θ value	9.24701e-21 (rank : 14)	NC score	0.795708 (rank : 10)
Query Neighborhood Hits	253	Target Neighborhood Hits	169	Shared Neighborhood Hits	106
SwissProt Accessions	P70169, Q6NXK3	Gene names	Doc2b
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

SYT2_MOUSE
θ value	9.24701e-21 (rank : 15)	NC score	0.789003 (rank : 16)
Query Neighborhood Hits	253	Target Neighborhood Hits	143	Shared Neighborhood Hits	105
SwissProt Accessions	P46097, Q8R0E1	Gene names	Syt2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT2_HUMAN
θ value	1.2077e-20 (rank : 16)	NC score	0.788950 (rank : 17)
Query Neighborhood Hits	253	Target Neighborhood Hits	142	Shared Neighborhood Hits	105
SwissProt Accessions	Q8N9I0, Q496K5, Q8NBE5	Gene names	SYT2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

RP3A_MOUSE
θ value	1.5773e-20 (rank : 17)	NC score	0.772763 (rank : 31)
Query Neighborhood Hits	253	Target Neighborhood Hits	510	Shared Neighborhood Hits	126
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

DOC2B_HUMAN
θ value	1.02238e-19 (rank : 18)	NC score	0.794141 (rank : 13)
Query Neighborhood Hits	253	Target Neighborhood Hits	150	Shared Neighborhood Hits	104
SwissProt Accessions	Q14184	Gene names	DOC2B
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

RP3A_HUMAN
θ value	1.33526e-19 (rank : 19)	NC score	0.777267 (rank : 26)
Query Neighborhood Hits	253	Target Neighborhood Hits	305	Shared Neighborhood Hits	115
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SYT11_HUMAN
θ value	2.27762e-19 (rank : 20)	NC score	0.775160 (rank : 29)
Query Neighborhood Hits	253	Target Neighborhood Hits	113	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BT88, Q14998, Q68CT5, Q8IXU3, Q96SU2	Gene names	SYT11, KIAA0080
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

SYT11_MOUSE
θ value	2.27762e-19 (rank : 21)	NC score	0.775757 (rank : 28)
Query Neighborhood Hits	253	Target Neighborhood Hits	116	Shared Neighborhood Hits	99
SwissProt Accessions	Q9R0N3	Gene names	Syt11
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

SYT10_HUMAN
θ value	5.07402e-19 (rank : 22)	NC score	0.776082 (rank : 27)
Query Neighborhood Hits	253	Target Neighborhood Hits	134	Shared Neighborhood Hits	102
SwissProt Accessions	Q6XYQ8	Gene names	SYT10
Domain Architecture	No domain graphic available
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

SYT10_MOUSE
θ value	8.65492e-19 (rank : 23)	NC score	0.773120 (rank : 30)
Query Neighborhood Hits	253	Target Neighborhood Hits	133	Shared Neighborhood Hits	103
SwissProt Accessions	Q9R0N4	Gene names	Syt10
Domain Architecture
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

SYT1_HUMAN
θ value	9.56915e-18 (rank : 24)	NC score	0.780910 (rank : 22)
Query Neighborhood Hits	253	Target Neighborhood Hits	150	Shared Neighborhood Hits	105
SwissProt Accessions	P21579	Gene names	SYT1, SYT
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT1_MOUSE
θ value	9.56915e-18 (rank : 25)	NC score	0.780887 (rank : 23)
Query Neighborhood Hits	253	Target Neighborhood Hits	150	Shared Neighborhood Hits	105
SwissProt Accessions	P46096	Gene names	Syt1
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT9_HUMAN
θ value	2.7842e-17 (rank : 26)	NC score	0.772577 (rank : 32)
Query Neighborhood Hits	253	Target Neighborhood Hits	144	Shared Neighborhood Hits	103
SwissProt Accessions	Q86SS6	Gene names	SYT9
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX).

SYT9_MOUSE
θ value	2.7842e-17 (rank : 27)	NC score	0.770927 (rank : 33)
Query Neighborhood Hits	253	Target Neighborhood Hits	148	Shared Neighborhood Hits	104
SwissProt Accessions	Q9R0N9, Q8C280	Gene names	Syt9, Syt5
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX) (Synaptotagmin V).

PCLO_HUMAN
θ value	1.058e-16 (rank : 28)	NC score	0.516327 (rank : 52)
Query Neighborhood Hits	253	Target Neighborhood Hits	2046	Shared Neighborhood Hits	171
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SYT4_HUMAN
θ value	2.35696e-16 (rank : 29)	NC score	0.770449 (rank : 34)
Query Neighborhood Hits	253	Target Neighborhood Hits	121	Shared Neighborhood Hits	100
SwissProt Accessions	Q9H2B2, Q9P2K4	Gene names	SYT4, KIAA1342
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

SYT4_MOUSE
θ value	2.35696e-16 (rank : 30)	NC score	0.768302 (rank : 35)
Query Neighborhood Hits	253	Target Neighborhood Hits	123	Shared Neighborhood Hits	98
SwissProt Accessions	P40749, Q3UFC1, Q8BGH3, Q8BRL6	Gene names	Syt4, Syt3
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

SYT5_HUMAN
θ value	8.95645e-16 (rank : 31)	NC score	0.785910 (rank : 19)
Query Neighborhood Hits	253	Target Neighborhood Hits	138	Shared Neighborhood Hits	105
SwissProt Accessions	O00445, Q86X72	Gene names	SYT5
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV).

DOC2A_HUMAN
θ value	1.99529e-15 (rank : 32)	NC score	0.791535 (rank : 15)
Query Neighborhood Hits	253	Target Neighborhood Hits	144	Shared Neighborhood Hits	102
SwissProt Accessions	Q14183, Q6P4G4, Q7Z5G0, Q8IVX0	Gene names	DOC2A
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha) (Doc2).

PCLO_MOUSE
θ value	2.60593e-15 (rank : 33)	NC score	0.486079 (rank : 55)
Query Neighborhood Hits	253	Target Neighborhood Hits	2275	Shared Neighborhood Hits	178
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SYT5_MOUSE
θ value	2.60593e-15 (rank : 34)	NC score	0.786213 (rank : 18)
Query Neighborhood Hits	253	Target Neighborhood Hits	140	Shared Neighborhood Hits	105
SwissProt Accessions	Q9R0N5	Gene names	Syt5, Syt9
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV) (Synaptotagmin IX).

DOC2A_MOUSE
θ value	3.40345e-15 (rank : 35)	NC score	0.792565 (rank : 14)
Query Neighborhood Hits	253	Target Neighborhood Hits	140	Shared Neighborhood Hits	101
SwissProt Accessions	Q7TNF0	Gene names	Doc2a
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha).

SYT7_MOUSE
θ value	1.09485e-13 (rank : 36)	NC score	0.781081 (rank : 21)
Query Neighborhood Hits	253	Target Neighborhood Hits	137	Shared Neighborhood Hits	104
SwissProt Accessions	Q9R0N7	Gene names	Syt7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

SYT7_HUMAN
θ value	7.09661e-13 (rank : 37)	NC score	0.780726 (rank : 24)
Query Neighborhood Hits	253	Target Neighborhood Hits	137	Shared Neighborhood Hits	104
SwissProt Accessions	O43581	Gene names	SYT7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

SYT12_MOUSE
θ value	2.69671e-12 (rank : 38)	NC score	0.748166 (rank : 37)
Query Neighborhood Hits	253	Target Neighborhood Hits	102	Shared Neighborhood Hits	88
SwissProt Accessions	Q920N7	Gene names	Syt12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

SYT15_HUMAN
θ value	8.67504e-11 (rank : 39)	NC score	0.739293 (rank : 39)
Query Neighborhood Hits	253	Target Neighborhood Hits	112	Shared Neighborhood Hits	91
SwissProt Accessions	Q9BQS2, Q7Z439, Q7Z440	Gene names	SYT15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV) (Chr10Syt).

DOC2G_MOUSE
θ value	1.133e-10 (rank : 40)	NC score	0.763108 (rank : 36)
Query Neighborhood Hits	253	Target Neighborhood Hits	125	Shared Neighborhood Hits	97
SwissProt Accessions	Q9ESN1, Q6P8R8	Gene names	Doc2g
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein gamma (Doc2-gamma).

SYT12_HUMAN
θ value	1.47974e-10 (rank : 41)	NC score	0.744024 (rank : 38)
Query Neighborhood Hits	253	Target Neighborhood Hits	100	Shared Neighborhood Hits	86
SwissProt Accessions	Q8IV01	Gene names	SYT12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

RIMS1_HUMAN
θ value	1.9326e-10 (rank : 42)	NC score	0.561191 (rank : 48)
Query Neighborhood Hits	253	Target Neighborhood Hits	437	Shared Neighborhood Hits	109
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

KPCG_HUMAN
θ value	2.52405e-10 (rank : 43)	NC score	0.206000 (rank : 95)
Query Neighborhood Hits	253	Target Neighborhood Hits	1126	Shared Neighborhood Hits	109
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

P3C2A_HUMAN
θ value	2.52405e-10 (rank : 44)	NC score	0.453910 (rank : 58)
Query Neighborhood Hits	253	Target Neighborhood Hits	188	Shared Neighborhood Hits	76
SwissProt Accessions	O00443	Gene names	PIK3C2A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha).

KPCG_MOUSE
θ value	3.29651e-10 (rank : 45)	NC score	0.205697 (rank : 96)
Query Neighborhood Hits	253	Target Neighborhood Hits	1123	Shared Neighborhood Hits	108
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

KPCA_HUMAN
θ value	5.62301e-10 (rank : 46)	NC score	0.191864 (rank : 99)
Query Neighborhood Hits	253	Target Neighborhood Hits	1070	Shared Neighborhood Hits	110
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

RASA3_HUMAN
θ value	1.25267e-09 (rank : 47)	NC score	0.418576 (rank : 66)
Query Neighborhood Hits	253	Target Neighborhood Hits	166	Shared Neighborhood Hits	82
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

P3C2A_MOUSE
θ value	1.63604e-09 (rank : 48)	NC score	0.450524 (rank : 59)
Query Neighborhood Hits	253	Target Neighborhood Hits	181	Shared Neighborhood Hits	79
SwissProt Accessions	Q61194, Q61182	Gene names	Pik3c2a, Cpk
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).

KPCA_MOUSE
θ value	2.13673e-09 (rank : 49)	NC score	0.188747 (rank : 101)
Query Neighborhood Hits	253	Target Neighborhood Hits	1067	Shared Neighborhood Hits	110
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KPCB_HUMAN
θ value	3.64472e-09 (rank : 50)	NC score	0.188607 (rank : 102)
Query Neighborhood Hits	253	Target Neighborhood Hits	1121	Shared Neighborhood Hits	109
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCB_MOUSE
θ value	4.76016e-09 (rank : 51)	NC score	0.190778 (rank : 100)
Query Neighborhood Hits	253	Target Neighborhood Hits	1117	Shared Neighborhood Hits	108
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

FA62A_HUMAN
θ value	8.11959e-09 (rank : 52)	NC score	0.630748 (rank : 42)
Query Neighborhood Hits	253	Target Neighborhood Hits	168	Shared Neighborhood Hits	102
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

FA62A_MOUSE
θ value	1.80886e-08 (rank : 53)	NC score	0.629473 (rank : 43)
Query Neighborhood Hits	253	Target Neighborhood Hits	155	Shared Neighborhood Hits	102
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

SYT15_MOUSE
θ value	5.26297e-08 (rank : 54)	NC score	0.700857 (rank : 41)
Query Neighborhood Hits	253	Target Neighborhood Hits	100	Shared Neighborhood Hits	85
SwissProt Accessions	Q8C6N3, Q7TN81, Q7TN82, Q8C999	Gene names	Syt15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV).

RASA2_MOUSE
θ value	4.45536e-07 (rank : 55)	NC score	0.444373 (rank : 61)
Query Neighborhood Hits	253	Target Neighborhood Hits	159	Shared Neighborhood Hits	82
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

RIMS2_HUMAN
θ value	4.45536e-07 (rank : 56)	NC score	0.546741 (rank : 50)
Query Neighborhood Hits	253	Target Neighborhood Hits	342	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
θ value	4.45536e-07 (rank : 57)	NC score	0.540532 (rank : 51)
Query Neighborhood Hits	253	Target Neighborhood Hits	376	Shared Neighborhood Hits	111
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

P3C2B_HUMAN
θ value	9.92553e-07 (rank : 58)	NC score	0.479542 (rank : 56)
Query Neighborhood Hits	253	Target Neighborhood Hits	148	Shared Neighborhood Hits	81
SwissProt Accessions	O00750, O95666, Q5SW99	Gene names	PIK3C2B
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-beta) (PtdIns-3-kinase C2 beta) (PI3K-C2beta) (C2-PI3K).

RASA2_HUMAN
θ value	1.29631e-06 (rank : 59)	NC score	0.438482 (rank : 62)
Query Neighborhood Hits	253	Target Neighborhood Hits	157	Shared Neighborhood Hits	82
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

SLC2B_HUMAN
θ value	1.29631e-06 (rank : 60)	NC score	0.209221 (rank : 94)
Query Neighborhood Hits	253	Target Neighborhood Hits	214	Shared Neighborhood Hits	31
SwissProt Accessions	Q8NEV8, Q9Y4D6	Gene names	EXPH5, KIAA0624, SLAC2B
Domain Architecture	No domain graphic available
Description	Slp homolog lacking C2 domains b (Exophilin-5).

SYT8_MOUSE
θ value	1.69304e-06 (rank : 61)	NC score	0.729915 (rank : 40)
Query Neighborhood Hits	253	Target Neighborhood Hits	94	Shared Neighborhood Hits	84
SwissProt Accessions	Q9R0N6, Q64366, Q8C6E7	Gene names	Syt8
Domain Architecture
Description	Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII).

RASA3_MOUSE
θ value	2.21117e-06 (rank : 62)	NC score	0.362483 (rank : 73)
Query Neighborhood Hits	253	Target Neighborhood Hits	144	Shared Neighborhood Hits	75
SwissProt Accessions	Q60790	Gene names	Rasa3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) (GapIII).

RFIP2_HUMAN
θ value	2.21117e-06 (rank : 63)	NC score	0.374588 (rank : 71)
Query Neighborhood Hits	253	Target Neighborhood Hits	97	Shared Neighborhood Hits	76
SwissProt Accessions	Q7L804, Q9Y2F0	Gene names	RAB11FIP2, KIAA0941
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 2 (Rab11-FIP2) (NRip11).

RIMS4_MOUSE
θ value	2.88788e-06 (rank : 64)	NC score	0.494515 (rank : 53)
Query Neighborhood Hits	253	Target Neighborhood Hits	76	Shared Neighborhood Hits	70
SwissProt Accessions	P60191	Gene names	Rims4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

RIMS4_HUMAN
θ value	3.77169e-06 (rank : 65)	NC score	0.491002 (rank : 54)
Query Neighborhood Hits	253	Target Neighborhood Hits	76	Shared Neighborhood Hits	70
SwissProt Accessions	Q9H426, Q5JWT7	Gene names	RIMS4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

NED4L_HUMAN
θ value	1.87187e-05 (rank : 66)	NC score	0.310837 (rank : 76)
Query Neighborhood Hits	253	Target Neighborhood Hits	238	Shared Neighborhood Hits	102
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NED4L_MOUSE
θ value	1.87187e-05 (rank : 67)	NC score	0.306873 (rank : 78)
Query Neighborhood Hits	253	Target Neighborhood Hits	231	Shared Neighborhood Hits	100
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

RASL2_HUMAN
θ value	2.44474e-05 (rank : 68)	NC score	0.560837 (rank : 49)
Query Neighborhood Hits	253	Target Neighborhood Hits	161	Shared Neighborhood Hits	98
SwissProt Accessions	O43374, O60286, Q86UW3, Q96QU0	Gene names	RASA4, CAPRI, GAPL, KIAA0538
Domain Architecture
Description	Ras GTPase-activating protein 4 (RasGAP-activating-like protein 2) (Calcium-promoted Ras inactivator).

NEDD4_HUMAN
θ value	4.1701e-05 (rank : 69)	NC score	0.289823 (rank : 84)
Query Neighborhood Hits	253	Target Neighborhood Hits	214	Shared Neighborhood Hits	100
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

DYSF_HUMAN
θ value	0.000158464 (rank : 70)	NC score	0.364455 (rank : 72)
Query Neighborhood Hits	253	Target Neighborhood Hits	170	Shared Neighborhood Hits	101
SwissProt Accessions	O75923, O75696, Q9UEN7	Gene names	DYSF, FER1L1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

NEDD4_MOUSE
θ value	0.00020696 (rank : 71)	NC score	0.276585 (rank : 87)
Query Neighborhood Hits	253	Target Neighborhood Hits	212	Shared Neighborhood Hits	99
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

MELPH_HUMAN
θ value	0.00035302 (rank : 72)	NC score	0.263873 (rank : 89)
Query Neighborhood Hits	253	Target Neighborhood Hits	145	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BV36, Q9HA71	Gene names	MLPH, SLAC2A
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Synaptotagmin-like protein 2a) (Slp homolog lacking C2 domains a).

MYRIP_HUMAN
θ value	0.00175202 (rank : 73)	NC score	0.262742 (rank : 90)
Query Neighborhood Hits	253	Target Neighborhood Hits	269	Shared Neighborhood Hits	37
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

P3C2G_MOUSE
θ value	0.00175202 (rank : 74)	NC score	0.196283 (rank : 98)
Query Neighborhood Hits	253	Target Neighborhood Hits	113	Shared Neighborhood Hits	61
SwissProt Accessions	O70167, O70168	Gene names	Pik3c2g
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).

OTOF_HUMAN
θ value	0.00228821 (rank : 75)	NC score	0.308057 (rank : 77)
Query Neighborhood Hits	253	Target Neighborhood Hits	168	Shared Neighborhood Hits	83
SwissProt Accessions	Q9HC10, Q9HC08, Q9HC09, Q9Y650	Gene names	OTOF, FER1L2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

MELPH_MOUSE
θ value	0.00298849 (rank : 76)	NC score	0.257012 (rank : 91)
Query Neighborhood Hits	253	Target Neighborhood Hits	112	Shared Neighborhood Hits	20
SwissProt Accessions	Q91V27, Q99N53	Gene names	Mlph, Ln, Slac2a
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Leaden protein) (Synaptotagmin-like protein 2a) (Slac2-a) (Slp homolog lacking C2 domains a).

OTOF_MOUSE
θ value	0.00298849 (rank : 77)	NC score	0.304718 (rank : 79)
Query Neighborhood Hits	253	Target Neighborhood Hits	196	Shared Neighborhood Hits	87
SwissProt Accessions	Q9ESF1, Q9ESF2	Gene names	Otof, Fer1l2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

P3C2G_HUMAN
θ value	0.00298849 (rank : 78)	NC score	0.177692 (rank : 106)
Query Neighborhood Hits	253	Target Neighborhood Hits	92	Shared Neighborhood Hits	45
SwissProt Accessions	O75747	Gene names	PIK3C2G
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).

K0528_HUMAN
θ value	0.00390308 (rank : 79)	NC score	0.421305 (rank : 64)
Query Neighborhood Hits	253	Target Neighborhood Hits	96	Shared Neighborhood Hits	79
SwissProt Accessions	Q86YS7, O60280, Q7Z619, Q86SU3	Gene names	KIAA0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

K0528_MOUSE
θ value	0.00390308 (rank : 80)	NC score	0.420608 (rank : 65)
Query Neighborhood Hits	253	Target Neighborhood Hits	102	Shared Neighborhood Hits	78
SwissProt Accessions	Q7TPS5, Q3TQY6, Q6A052, Q80VA1, Q8C0U3, Q8CID5, Q9CS85	Gene names	Kiaa0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

SYT14_MOUSE
θ value	0.00390308 (rank : 81)	NC score	0.580211 (rank : 46)
Query Neighborhood Hits	253	Target Neighborhood Hits	82	Shared Neighborhood Hits	66
SwissProt Accessions	Q7TN84	Gene names	Syt14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

DYSF_MOUSE
θ value	0.00509761 (rank : 82)	NC score	0.358971 (rank : 74)
Query Neighborhood Hits	253	Target Neighborhood Hits	162	Shared Neighborhood Hits	104
SwissProt Accessions	Q9ESD7, Q9QXC0	Gene names	Dysf, Fer1l1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

SYT14_HUMAN
θ value	0.00509761 (rank : 83)	NC score	0.577492 (rank : 47)
Query Neighborhood Hits	253	Target Neighborhood Hits	81	Shared Neighborhood Hits	60
SwissProt Accessions	Q8NB59, Q5THX7, Q707N3, Q707N4, Q707N5, Q707N6, Q707N7	Gene names	SYT14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

RASL1_MOUSE
θ value	0.00665767 (rank : 84)	NC score	0.448602 (rank : 60)
Query Neighborhood Hits	253	Target Neighborhood Hits	148	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Z268	Gene names	Rasal1, Rasal
Domain Architecture
Description	RasGAP-activating-like protein 1.

UN13A_HUMAN
θ value	0.00665767 (rank : 85)	NC score	0.299770 (rank : 80)
Query Neighborhood Hits	253	Target Neighborhood Hits	285	Shared Neighborhood Hits	100
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

LEO1_HUMAN
θ value	0.0113563 (rank : 86)	NC score	0.053040 (rank : 165)
Query Neighborhood Hits	253	Target Neighborhood Hits	958	Shared Neighborhood Hits	61
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

MYOF_HUMAN
θ value	0.0113563 (rank : 87)	NC score	0.353639 (rank : 75)
Query Neighborhood Hits	253	Target Neighborhood Hits	147	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NZM1, Q9HBU3, Q9NZM0, Q9ULL3, Q9Y4U4	Gene names	FER1L3, KIAA1207, MYOF
Domain Architecture
Description	Myoferlin (Fer-1-like protein 3).

XRCC4_HUMAN
θ value	0.0113563 (rank : 88)	NC score	0.046534 (rank : 174)
Query Neighborhood Hits	253	Target Neighborhood Hits	131	Shared Neighborhood Hits	8
SwissProt Accessions	Q13426, Q9BS72, Q9UP94	Gene names	XRCC4
Domain Architecture
Description	DNA-repair protein XRCC4 (X-ray repair cross-complementing protein 4).

MYRIP_MOUSE
θ value	0.0148317 (rank : 89)	NC score	0.266442 (rank : 88)
Query Neighborhood Hits	253	Target Neighborhood Hits	207	Shared Neighborhood Hits	38
SwissProt Accessions	Q8K3I4, Q8CFC0, Q8K4H5	Gene names	Myrip, Slac2c
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

PA24D_HUMAN
θ value	0.0148317 (rank : 90)	NC score	0.254718 (rank : 92)
Query Neighborhood Hits	253	Target Neighborhood Hits	97	Shared Neighborhood Hits	77
SwissProt Accessions	Q86XP0, Q8N176	Gene names	PLA2G4D
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

SYT13_HUMAN
θ value	0.0193708 (rank : 91)	NC score	0.601217 (rank : 44)
Query Neighborhood Hits	253	Target Neighborhood Hits	76	Shared Neighborhood Hits	66
SwissProt Accessions	Q7L8C5, Q9BQS3, Q9H041, Q9P2C0	Gene names	SYT13, KIAA1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

SYT13_MOUSE
θ value	0.0193708 (rank : 92)	NC score	0.593591 (rank : 45)
Query Neighborhood Hits	253	Target Neighborhood Hits	69	Shared Neighborhood Hits	66
SwissProt Accessions	Q9EQT6, Q6ZPR2, Q8BRK6	Gene names	Syt13, Kiaa1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

RASL1_HUMAN
θ value	0.0252991 (rank : 93)	NC score	0.458779 (rank : 57)
Query Neighborhood Hits	253	Target Neighborhood Hits	142	Shared Neighborhood Hits	88
SwissProt Accessions	O95294, Q52M03, Q96CC7	Gene names	RASAL1, RASAL
Domain Architecture
Description	RasGAP-activating-like protein 1.

RGS3_HUMAN
θ value	0.0252991 (rank : 94)	NC score	0.214848 (rank : 93)
Query Neighborhood Hits	253	Target Neighborhood Hits	1375	Shared Neighborhood Hits	121
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

UN13B_MOUSE
θ value	0.0252991 (rank : 95)	NC score	0.296358 (rank : 81)
Query Neighborhood Hits	253	Target Neighborhood Hits	210	Shared Neighborhood Hits	89
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

RFIP1_MOUSE
θ value	0.0330416 (rank : 96)	NC score	0.188002 (rank : 103)
Query Neighborhood Hits	253	Target Neighborhood Hits	152	Shared Neighborhood Hits	49
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

WWC3_HUMAN
θ value	0.0330416 (rank : 97)	NC score	0.036995 (rank : 189)
Query Neighborhood Hits	253	Target Neighborhood Hits	193	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ULE0, Q659C1, Q9BTQ1	Gene names	WWC3, KIAA1280
Domain Architecture	No domain graphic available
Description	WWC family member 3.

PA24D_MOUSE
θ value	0.0431538 (rank : 98)	NC score	0.291667 (rank : 83)
Query Neighborhood Hits	253	Target Neighborhood Hits	100	Shared Neighborhood Hits	80
SwissProt Accessions	Q50L43, Q3TJC5	Gene names	Pla2g4d
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

RBBP6_HUMAN
θ value	0.0431538 (rank : 99)	NC score	0.057650 (rank : 153)
Query Neighborhood Hits	253	Target Neighborhood Hits	1135	Shared Neighborhood Hits	74
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

SVIL_MOUSE
θ value	0.0431538 (rank : 100)	NC score	0.034380 (rank : 194)
Query Neighborhood Hits	253	Target Neighborhood Hits	439	Shared Neighborhood Hits	34
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

UN13B_HUMAN
θ value	0.0431538 (rank : 101)	NC score	0.291974 (rank : 82)
Query Neighborhood Hits	253	Target Neighborhood Hits	217	Shared Neighborhood Hits	94
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

RFIP1_HUMAN
θ value	0.0563607 (rank : 102)	NC score	0.183811 (rank : 105)
Query Neighborhood Hits	253	Target Neighborhood Hits	236	Shared Neighborhood Hits	58
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

TCAL5_MOUSE
θ value	0.0563607 (rank : 103)	NC score	0.043062 (rank : 180)
Query Neighborhood Hits	253	Target Neighborhood Hits	63	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CCT4, Q497R6	Gene names	Tceal5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

TXND2_HUMAN
θ value	0.0563607 (rank : 104)	NC score	0.059942 (rank : 148)
Query Neighborhood Hits	253	Target Neighborhood Hits	793	Shared Neighborhood Hits	65
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

AKA12_HUMAN
θ value	0.0961366 (rank : 105)	NC score	0.063982 (rank : 146)
Query Neighborhood Hits	253	Target Neighborhood Hits	825	Shared Neighborhood Hits	74
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

ATRX_MOUSE
θ value	0.0961366 (rank : 106)	NC score	0.044876 (rank : 178)
Query Neighborhood Hits	253	Target Neighborhood Hits	682	Shared Neighborhood Hits	49
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

MARCS_HUMAN
θ value	0.0961366 (rank : 107)	NC score	0.069038 (rank : 141)
Query Neighborhood Hits	253	Target Neighborhood Hits	204	Shared Neighborhood Hits	20
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

MCPH1_MOUSE
θ value	0.0961366 (rank : 108)	NC score	0.042839 (rank : 181)
Query Neighborhood Hits	253	Target Neighborhood Hits	116	Shared Neighborhood Hits	8
SwissProt Accessions	Q7TT79, Q8BNI9, Q8C9I7	Gene names	Mcph1
Domain Architecture
Description	Microcephalin.

MINT_HUMAN
θ value	0.0961366 (rank : 109)	NC score	0.049491 (rank : 173)
Query Neighborhood Hits	253	Target Neighborhood Hits	1291	Shared Neighborhood Hits	75
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

PININ_HUMAN
θ value	0.0961366 (rank : 110)	NC score	0.049671 (rank : 172)
Query Neighborhood Hits	253	Target Neighborhood Hits	753	Shared Neighborhood Hits	51
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

ASXL1_MOUSE
θ value	0.125558 (rank : 111)	NC score	0.045184 (rank : 176)
Query Neighborhood Hits	253	Target Neighborhood Hits	182	Shared Neighborhood Hits	21
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

CD2L1_MOUSE
θ value	0.125558 (rank : 112)	NC score	0.016864 (rank : 242)
Query Neighborhood Hits	253	Target Neighborhood Hits	1463	Shared Neighborhood Hits	57
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

NFH_MOUSE
θ value	0.125558 (rank : 113)	NC score	0.035748 (rank : 190)
Query Neighborhood Hits	253	Target Neighborhood Hits	2247	Shared Neighborhood Hits	97
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

DSPP_MOUSE
θ value	0.163984 (rank : 114)	NC score	0.057109 (rank : 155)
Query Neighborhood Hits	253	Target Neighborhood Hits	491	Shared Neighborhood Hits	47
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

TAB3_HUMAN
θ value	0.163984 (rank : 115)	NC score	0.033751 (rank : 197)
Query Neighborhood Hits	253	Target Neighborhood Hits	168	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N5C8, Q6VQR0	Gene names	MAP3K7IP3, TAB3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3) (NF-kappa-B-activating protein 1).

TDRD5_HUMAN
θ value	0.163984 (rank : 116)	NC score	0.034925 (rank : 193)
Query Neighborhood Hits	253	Target Neighborhood Hits	65	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NAT2, Q5VTV0	Gene names	TDRD5
Domain Architecture
Description	Tudor domain-containing protein 5.

ATRX_HUMAN
θ value	0.21417 (rank : 117)	NC score	0.037372 (rank : 188)
Query Neighborhood Hits	253	Target Neighborhood Hits	842	Shared Neighborhood Hits	61
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

RSF1_HUMAN
θ value	0.21417 (rank : 118)	NC score	0.042422 (rank : 183)
Query Neighborhood Hits	253	Target Neighborhood Hits	539	Shared Neighborhood Hits	47
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

BBX_MOUSE
θ value	0.279714 (rank : 119)	NC score	0.027326 (rank : 208)
Query Neighborhood Hits	253	Target Neighborhood Hits	152	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VBW5, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VI48, Q8VI49, Q8VI50, Q9CS94	Gene names	Bbx, Hbp2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

FA13A_MOUSE
θ value	0.279714 (rank : 120)	NC score	0.020489 (rank : 226)
Query Neighborhood Hits	253	Target Neighborhood Hits	83	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BGI4, Q8BZ91	Gene names	Fam13a1, Precm1
Domain Architecture	No domain graphic available
Description	Protein FAM13A1 (Precm1 protein).

PDZD8_HUMAN
θ value	0.279714 (rank : 121)	NC score	0.069042 (rank : 140)
Query Neighborhood Hits	253	Target Neighborhood Hits	185	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

FRMD6_HUMAN
θ value	0.365318 (rank : 122)	NC score	0.017337 (rank : 241)
Query Neighborhood Hits	253	Target Neighborhood Hits	60	Shared Neighborhood Hits	5
SwissProt Accessions	Q96NE9, Q5HYF2, Q8N2X1, Q8WUH7	Gene names	FRMD6, C14orf31
Domain Architecture
Description	FERM domain-containing protein 6 (Willin).

LPIN2_HUMAN
θ value	0.365318 (rank : 123)	NC score	0.022440 (rank : 221)
Query Neighborhood Hits	253	Target Neighborhood Hits	117	Shared Neighborhood Hits	13
SwissProt Accessions	Q92539	Gene names	LPIN2, KIAA0249
Domain Architecture	No domain graphic available
Description	Lipin-2.

RNC_HUMAN
θ value	0.365318 (rank : 124)	NC score	0.032685 (rank : 199)
Query Neighborhood Hits	253	Target Neighborhood Hits	176	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

ARI1B_HUMAN
θ value	0.47712 (rank : 125)	NC score	0.032803 (rank : 198)
Query Neighborhood Hits	253	Target Neighborhood Hits	567	Shared Neighborhood Hits	34
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

CBP_MOUSE
θ value	0.47712 (rank : 126)	NC score	0.035732 (rank : 191)
Query Neighborhood Hits	253	Target Neighborhood Hits	1051	Shared Neighborhood Hits	46
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CIR_HUMAN
θ value	0.47712 (rank : 127)	NC score	0.035471 (rank : 192)
Query Neighborhood Hits	253	Target Neighborhood Hits	249	Shared Neighborhood Hits	23
SwissProt Accessions	Q86X95, O95367, Q12804, Q4G1B9, Q6PJI4, Q8IWI2	Gene names	CIR
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor (Recepin).

CPNE7_HUMAN
θ value	0.47712 (rank : 128)	NC score	0.155875 (rank : 117)
Query Neighborhood Hits	253	Target Neighborhood Hits	92	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UBL6	Gene names	CPNE7
Domain Architecture
Description	Copine-7 (Copine VII).

ERIC1_HUMAN
θ value	0.47712 (rank : 129)	NC score	0.044223 (rank : 179)
Query Neighborhood Hits	253	Target Neighborhood Hits	364	Shared Neighborhood Hits	35
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

NDEL1_HUMAN
θ value	0.47712 (rank : 130)	NC score	0.018132 (rank : 236)
Query Neighborhood Hits	253	Target Neighborhood Hits	415	Shared Neighborhood Hits	8
SwissProt Accessions	Q9GZM8, Q86T80, Q8TAR7, Q9UH50	Gene names	NDEL1, EOPA, MITAP1, NUDEL
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE-like 1 (Protein Nudel) (Mitosin- associated protein 1).

NDEL1_MOUSE
θ value	0.47712 (rank : 131)	NC score	0.018152 (rank : 235)
Query Neighborhood Hits	253	Target Neighborhood Hits	420	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ERR1, Q9D0Q4, Q9EPT6	Gene names	Ndel1, Nudel
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE-like 1 (Protein Nudel) (Protein mNudE-like) (mNudE-L).

NU214_HUMAN
θ value	0.47712 (rank : 132)	NC score	0.029448 (rank : 204)
Query Neighborhood Hits	253	Target Neighborhood Hits	657	Shared Neighborhood Hits	32
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

TNR6A_HUMAN
θ value	0.47712 (rank : 133)	NC score	0.032101 (rank : 200)
Query Neighborhood Hits	253	Target Neighborhood Hits	343	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

FGD6_MOUSE
θ value	0.62314 (rank : 134)	NC score	0.016611 (rank : 243)
Query Neighborhood Hits	253	Target Neighborhood Hits	282	Shared Neighborhood Hits	16
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

ITSN2_HUMAN
θ value	0.62314 (rank : 135)	NC score	0.150064 (rank : 119)
Query Neighborhood Hits	253	Target Neighborhood Hits	1173	Shared Neighborhood Hits	97
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

MYST3_MOUSE
θ value	0.62314 (rank : 136)	NC score	0.034228 (rank : 196)
Query Neighborhood Hits	253	Target Neighborhood Hits	688	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

TRIPC_HUMAN
θ value	0.62314 (rank : 137)	NC score	0.045529 (rank : 175)
Query Neighborhood Hits	253	Target Neighborhood Hits	319	Shared Neighborhood Hits	29
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

ANR11_HUMAN
θ value	0.813845 (rank : 138)	NC score	0.023870 (rank : 213)
Query Neighborhood Hits	253	Target Neighborhood Hits	1289	Shared Neighborhood Hits	64
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

CPNE5_HUMAN
θ value	0.813845 (rank : 139)	NC score	0.166124 (rank : 111)
Query Neighborhood Hits	253	Target Neighborhood Hits	88	Shared Neighborhood Hits	64
SwissProt Accessions	Q9HCH3	Gene names	CPNE5, KIAA1599
Domain Architecture
Description	Copine-5 (Copine V).

ENL_HUMAN
θ value	0.813845 (rank : 140)	NC score	0.056644 (rank : 159)
Query Neighborhood Hits	253	Target Neighborhood Hits	305	Shared Neighborhood Hits	34
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

K0494_MOUSE
θ value	0.813845 (rank : 141)	NC score	0.018927 (rank : 232)
Query Neighborhood Hits	253	Target Neighborhood Hits	241	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BGQ6, Q3TQN6, Q8BJV7, Q8C0R1	Gene names	Kiaa0494
Domain Architecture	No domain graphic available
Description	Uncharacterized calcium-binding protein KIAA0494.

MYO9B_HUMAN
θ value	0.813845 (rank : 142)	NC score	0.019951 (rank : 230)
Query Neighborhood Hits	253	Target Neighborhood Hits	641	Shared Neighborhood Hits	46
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

PRGC2_HUMAN
θ value	0.813845 (rank : 143)	NC score	0.023412 (rank : 218)
Query Neighborhood Hits	253	Target Neighborhood Hits	272	Shared Neighborhood Hits	17
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

RBBP6_MOUSE
θ value	0.813845 (rank : 144)	NC score	0.058099 (rank : 152)
Query Neighborhood Hits	253	Target Neighborhood Hits	1014	Shared Neighborhood Hits	64
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

TAB3_MOUSE
θ value	0.813845 (rank : 145)	NC score	0.034250 (rank : 195)
Query Neighborhood Hits	253	Target Neighborhood Hits	273	Shared Neighborhood Hits	18
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

AP3B2_MOUSE
θ value	1.06291 (rank : 146)	NC score	0.021203 (rank : 222)
Query Neighborhood Hits	253	Target Neighborhood Hits	246	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JME5, Q6QR53, Q8R1E5	Gene names	Ap3b2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain).

ERCC5_HUMAN
θ value	1.06291 (rank : 147)	NC score	0.023706 (rank : 216)
Query Neighborhood Hits	253	Target Neighborhood Hits	162	Shared Neighborhood Hits	23
SwissProt Accessions	P28715, Q7Z2V3, Q8IZL6, Q8N1B7, Q9HD59	Gene names	ERCC5, XPG, XPGC
Domain Architecture
Description	DNA-repair protein complementing XP-G cells (Xeroderma pigmentosum group G-complementing protein) (DNA excision repair protein ERCC-5).

JHD2A_MOUSE
θ value	1.06291 (rank : 148)	NC score	0.018327 (rank : 234)
Query Neighborhood Hits	253	Target Neighborhood Hits	123	Shared Neighborhood Hits	12
SwissProt Accessions	Q6PCM1, Q2MJQ6, Q3TKW8, Q3UML3, Q6ZQ57, Q8K2J6, Q8K2K4, Q8R350	Gene names	Jmjd1a, Jhdm2a, Kiaa0742
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2A (EC 1.14.11.-) (Jumonji domain-containing protein 1A).

MASTL_MOUSE
θ value	1.06291 (rank : 149)	NC score	0.020134 (rank : 228)
Query Neighborhood Hits	253	Target Neighborhood Hits	862	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C0P0, Q5RJW0, Q6NXX9, Q8BVF3, Q9CZH9, Q9D9V0	Gene names	Mastl
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase-like (EC 2.7.11.1).

ORC2_HUMAN
θ value	1.06291 (rank : 150)	NC score	0.020650 (rank : 224)
Query Neighborhood Hits	253	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	Q13416, Q13204	Gene names	ORC2L, ORC2
Domain Architecture
Description	Origin recognition complex subunit 2.

OXR1_MOUSE
θ value	1.06291 (rank : 151)	NC score	0.039462 (rank : 186)
Query Neighborhood Hits	253	Target Neighborhood Hits	516	Shared Neighborhood Hits	53
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

PININ_MOUSE
θ value	1.06291 (rank : 152)	NC score	0.039573 (rank : 185)
Query Neighborhood Hits	253	Target Neighborhood Hits	777	Shared Neighborhood Hits	49
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

RERE_MOUSE
θ value	1.06291 (rank : 153)	NC score	0.028625 (rank : 206)
Query Neighborhood Hits	253	Target Neighborhood Hits	785	Shared Neighborhood Hits	40
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

ANR12_HUMAN
θ value	1.38821 (rank : 154)	NC score	0.010239 (rank : 263)
Query Neighborhood Hits	253	Target Neighborhood Hits	1081	Shared Neighborhood Hits	44
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

BAZ2B_HUMAN
θ value	1.38821 (rank : 155)	NC score	0.021116 (rank : 223)
Query Neighborhood Hits	253	Target Neighborhood Hits	803	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

NOLC1_HUMAN
θ value	1.38821 (rank : 156)	NC score	0.064512 (rank : 144)
Query Neighborhood Hits	253	Target Neighborhood Hits	452	Shared Neighborhood Hits	46
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

PALB2_HUMAN
θ value	1.38821 (rank : 157)	NC score	0.020032 (rank : 229)
Query Neighborhood Hits	253	Target Neighborhood Hits	117	Shared Neighborhood Hits	7
SwissProt Accessions	Q86YC2, Q8N7Y6, Q8ND31, Q9H6W1	Gene names	PALB2
Domain Architecture	No domain graphic available
Description	Partner and localizer of BRCA2.

PCX1_HUMAN
θ value	1.38821 (rank : 158)	NC score	0.017877 (rank : 239)
Query Neighborhood Hits	253	Target Neighborhood Hits	102	Shared Neighborhood Hits	8
SwissProt Accessions	Q96RV3, O94897, Q96AI7, Q9Y2J9	Gene names	PCNX, KIAA0805, KIAA0995, PCNXL1
Domain Architecture
Description	Pecanex-like protein 1 (Pecanex homolog).

RTN2_HUMAN
θ value	1.38821 (rank : 159)	NC score	0.015946 (rank : 247)
Query Neighborhood Hits	253	Target Neighborhood Hits	59	Shared Neighborhood Hits	5
SwissProt Accessions	O75298, O60509, Q7RTM6, Q7RTN1, Q7RTN2	Gene names	RTN2, NSPL1
Domain Architecture
Description	Reticulon-2 (Neuroendocrine-specific protein-like 1) (NSP-like protein 1) (NSPLI).

TITIN_HUMAN
θ value	1.38821 (rank : 160)	NC score	0.018649 (rank : 233)
Query Neighborhood Hits	253	Target Neighborhood Hits	2923	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

AMPH_MOUSE
θ value	1.81305 (rank : 161)	NC score	0.017765 (rank : 240)
Query Neighborhood Hits	253	Target Neighborhood Hits	291	Shared Neighborhood Hits	20
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

AP3D1_MOUSE
θ value	1.81305 (rank : 162)	NC score	0.012237 (rank : 257)
Query Neighborhood Hits	253	Target Neighborhood Hits	144	Shared Neighborhood Hits	13
SwissProt Accessions	O54774	Gene names	Ap3d1, Ap3d
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin) (mBLVR1).

ARP5_MOUSE
θ value	1.81305 (rank : 163)	NC score	0.009307 (rank : 267)
Query Neighborhood Hits	253	Target Neighborhood Hits	116	Shared Neighborhood Hits	2
SwissProt Accessions	Q80US4, Q8BL26	Gene names	Actr5
Domain Architecture	No domain graphic available
Description	Actin-related protein 5.

CPNE8_HUMAN
θ value	1.81305 (rank : 164)	NC score	0.160269 (rank : 113)
Query Neighborhood Hits	253	Target Neighborhood Hits	86	Shared Neighborhood Hits	64
SwissProt Accessions	Q86YQ8, Q2TB41	Gene names	CPNE8
Domain Architecture
Description	Copine-8 (Copine VIII).

CPNE8_MOUSE
θ value	1.81305 (rank : 165)	NC score	0.156768 (rank : 116)
Query Neighborhood Hits	253	Target Neighborhood Hits	85	Shared Neighborhood Hits	64
SwissProt Accessions	Q9DC53, Q9CUZ8	Gene names	Cpne8
Domain Architecture
Description	Copine-8 (Copine VIII).

ITSN1_HUMAN
θ value	1.81305 (rank : 166)	NC score	0.104893 (rank : 134)
Query Neighborhood Hits	253	Target Neighborhood Hits	1757	Shared Neighborhood Hits	110
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN1_MOUSE
θ value	1.81305 (rank : 167)	NC score	0.107415 (rank : 129)
Query Neighborhood Hits	253	Target Neighborhood Hits	1669	Shared Neighborhood Hits	116
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

IWS1_HUMAN
θ value	1.81305 (rank : 168)	NC score	0.068512 (rank : 142)
Query Neighborhood Hits	253	Target Neighborhood Hits	1241	Shared Neighborhood Hits	89
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

IWS1_MOUSE
θ value	1.81305 (rank : 169)	NC score	0.057285 (rank : 154)
Query Neighborhood Hits	253	Target Neighborhood Hits	1258	Shared Neighborhood Hits	89
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MINT_MOUSE
θ value	1.81305 (rank : 170)	NC score	0.044933 (rank : 177)
Query Neighborhood Hits	253	Target Neighborhood Hits	1514	Shared Neighborhood Hits	74
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MYST4_HUMAN
θ value	1.81305 (rank : 171)	NC score	0.026348 (rank : 210)
Query Neighborhood Hits	253	Target Neighborhood Hits	671	Shared Neighborhood Hits	51
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

CCD55_MOUSE
θ value	2.36792 (rank : 172)	NC score	0.031522 (rank : 202)
Query Neighborhood Hits	253	Target Neighborhood Hits	519	Shared Neighborhood Hits	47
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

CRCM_HUMAN
θ value	2.36792 (rank : 173)	NC score	0.015533 (rank : 250)
Query Neighborhood Hits	253	Target Neighborhood Hits	520	Shared Neighborhood Hits	16
SwissProt Accessions	P23508	Gene names	MCC
Domain Architecture
Description	Colorectal mutant cancer protein (Protein MCC).

DCX_MOUSE
θ value	2.36792 (rank : 174)	NC score	0.012752 (rank : 255)
Query Neighborhood Hits	253	Target Neighborhood Hits	124	Shared Neighborhood Hits	14
SwissProt Accessions	O88809	Gene names	Dcx, Dcn
Domain Architecture
Description	Neuronal migration protein doublecortin (Lissencephalin-X) (Lis-X) (Doublin).

DSPP_HUMAN
θ value	2.36792 (rank : 175)	NC score	0.056391 (rank : 160)
Query Neighborhood Hits	253	Target Neighborhood Hits	645	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

HS105_MOUSE
θ value	2.36792 (rank : 176)	NC score	0.006388 (rank : 283)
Query Neighborhood Hits	253	Target Neighborhood Hits	129	Shared Neighborhood Hits	11
SwissProt Accessions	Q61699, Q3TNS2, Q3UIY8, Q62578, Q62579, Q6A0A5, Q8C430, Q8VCW6	Gene names	Hsph1, Hsp105, Hsp110, Kiaa0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock-related 100 kDa protein E7I) (HSP-E7I) (Heat shock 110 kDa protein) (42 degrees C-HSP).

LYST_HUMAN
θ value	2.36792 (rank : 177)	NC score	0.007265 (rank : 280)
Query Neighborhood Hits	253	Target Neighborhood Hits	324	Shared Neighborhood Hits	11
SwissProt Accessions	Q99698, O43274, Q5T2U9, Q96TD7, Q96TD8, Q99709, Q9H133	Gene names	LYST, CHS, CHS1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige homolog).

PCDGF_HUMAN
θ value	2.36792 (rank : 178)	NC score	-0.001054 (rank : 297)
Query Neighborhood Hits	253	Target Neighborhood Hits	162	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5G1, Q9Y5C7	Gene names	PCDHGB3
Domain Architecture
Description	Protocadherin gamma B3 precursor (PCDH-gamma-B3).

PHC3_MOUSE
θ value	2.36792 (rank : 179)	NC score	0.015748 (rank : 248)
Query Neighborhood Hits	253	Target Neighborhood Hits	194	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CHP6, Q3TLV5	Gene names	Phc3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3.

PZRN3_MOUSE
θ value	2.36792 (rank : 180)	NC score	0.007486 (rank : 276)
Query Neighborhood Hits	253	Target Neighborhood Hits	447	Shared Neighborhood Hits	13
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

SPF45_MOUSE
θ value	2.36792 (rank : 181)	NC score	0.016314 (rank : 245)
Query Neighborhood Hits	253	Target Neighborhood Hits	95	Shared Neighborhood Hits	6
SwissProt Accessions	Q8JZX4, O75939	Gene names	Rbm17, Spf45
Domain Architecture
Description	Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17).

SRRM2_MOUSE
θ value	2.36792 (rank : 182)	NC score	0.059368 (rank : 151)
Query Neighborhood Hits	253	Target Neighborhood Hits	1470	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TCAL3_MOUSE
θ value	2.36792 (rank : 183)	NC score	0.039757 (rank : 184)
Query Neighborhood Hits	253	Target Neighborhood Hits	132	Shared Neighborhood Hits	22
SwissProt Accessions	Q8R0A5, Q9CYK5, Q9D1S4	Gene names	Tceal3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

EFG2_MOUSE
θ value	3.0926 (rank : 184)	NC score	0.008771 (rank : 269)
Query Neighborhood Hits	253	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R2Q4	Gene names	Gfm2, Efg2
Domain Architecture
Description	Elongation factor G 2, mitochondrial precursor (mEF-G 2) (Elongation factor G2).

HBP1_MOUSE
θ value	3.0926 (rank : 185)	NC score	0.010275 (rank : 262)
Query Neighborhood Hits	253	Target Neighborhood Hits	86	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R316, Q3V0I4, Q8BUS3, Q8C199	Gene names	Hbp1
Domain Architecture	No domain graphic available
Description	HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1).

NUDC_MOUSE
θ value	3.0926 (rank : 186)	NC score	0.013736 (rank : 251)
Query Neighborhood Hits	253	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	O35685, Q3UJS7	Gene names	Nudc
Domain Architecture	No domain graphic available
Description	Nuclear migration protein nudC (Nuclear distribution protein C homolog) (Silica-induced gene 92 protein) (SIG-92).

UBP24_HUMAN
θ value	3.0926 (rank : 187)	NC score	0.005778 (rank : 287)
Query Neighborhood Hits	253	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPU5, Q6ZSY2, Q8N2Y4, Q9NXD1	Gene names	USP24, KIAA1057
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.1.2.15) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) (Deubiquitinating enzyme 24).

UN13D_HUMAN
θ value	3.0926 (rank : 188)	NC score	0.438466 (rank : 63)
Query Neighborhood Hits	253	Target Neighborhood Hits	117	Shared Neighborhood Hits	90
SwissProt Accessions	Q70J99, Q9H7K5	Gene names	UNC13D
Domain Architecture	No domain graphic available
Description	Unc-13 homolog D (Munc13-4).

ZCH11_HUMAN
θ value	3.0926 (rank : 189)	NC score	0.020185 (rank : 227)
Query Neighborhood Hits	253	Target Neighborhood Hits	278	Shared Neighborhood Hits	24
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

ZGPAT_HUMAN
θ value	3.0926 (rank : 190)	NC score	0.013005 (rank : 254)
Query Neighborhood Hits	253	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N5A5, Q5JWI9, Q8NC55, Q96JI0, Q96JU4, Q9H401	Gene names	ZGPAT, KIAA1847, ZC3H9, ZC3HDC9
Domain Architecture
Description	Zinc finger CCCH-type with G patch domain protein (Zinc finger CCCH domain-containing protein 9).

CPNE5_MOUSE
θ value	4.03905 (rank : 191)	NC score	0.164737 (rank : 112)
Query Neighborhood Hits	253	Target Neighborhood Hits	86	Shared Neighborhood Hits	64
SwissProt Accessions	Q8JZW4	Gene names	Cpne5
Domain Architecture
Description	Copine-5 (Copine V).

DAXX_MOUSE
θ value	4.03905 (rank : 192)	NC score	0.023809 (rank : 214)
Query Neighborhood Hits	253	Target Neighborhood Hits	173	Shared Neighborhood Hits	16
SwissProt Accessions	O35613, Q9QWT8, Q9QWV3	Gene names	Daxx
Domain Architecture
Description	Death domain-associated protein 6 (Daxx).

ICAL_HUMAN
θ value	4.03905 (rank : 193)	NC score	0.027057 (rank : 209)
Query Neighborhood Hits	253	Target Neighborhood Hits	275	Shared Neighborhood Hits	37
SwissProt Accessions	P20810, O95360, Q96D08, Q9H1Z5	Gene names	CAST
Domain Architecture
Description	Calpastatin (Calpain inhibitor) (Sperm BS-17 component).

MAP1B_HUMAN
θ value	4.03905 (rank : 194)	NC score	0.037794 (rank : 187)
Query Neighborhood Hits	253	Target Neighborhood Hits	903	Shared Neighborhood Hits	72
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

NALP5_MOUSE
θ value	4.03905 (rank : 195)	NC score	0.023768 (rank : 215)
Query Neighborhood Hits	253	Target Neighborhood Hits	560	Shared Neighborhood Hits	56
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

RBP26_HUMAN
θ value	4.03905 (rank : 196)	NC score	0.007453 (rank : 278)
Query Neighborhood Hits	253	Target Neighborhood Hits	146	Shared Neighborhood Hits	12
SwissProt Accessions	Q68DN6, Q6V1X0	Gene names	RANBP2L6
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 6 (RanBP2L6).

TRHY_HUMAN
θ value	4.03905 (rank : 197)	NC score	0.005901 (rank : 285)
Query Neighborhood Hits	253	Target Neighborhood Hits	1385	Shared Neighborhood Hits	51
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

BNI3L_HUMAN
θ value	5.27518 (rank : 198)	NC score	0.016414 (rank : 244)
Query Neighborhood Hits	253	Target Neighborhood Hits	15	Shared Neighborhood Hits	6
SwissProt Accessions	O60238	Gene names	BNIP3L, BNIP3A, BNIP3H, NIX
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like (NIP3L) (NIP3-like protein X) (BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A).

BNI3L_MOUSE
θ value	5.27518 (rank : 199)	NC score	0.016138 (rank : 246)
Query Neighborhood Hits	253	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z2F7, Q545J6	Gene names	Bnip3l, Nix
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like (NIP3L) (NIP3-like protein X).

BRPF3_HUMAN
θ value	5.27518 (rank : 200)	NC score	0.009046 (rank : 268)
Query Neighborhood Hits	253	Target Neighborhood Hits	217	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

CKAP2_HUMAN
θ value	5.27518 (rank : 201)	NC score	0.017962 (rank : 238)
Query Neighborhood Hits	253	Target Neighborhood Hits	116	Shared Neighborhood Hits	14
SwissProt Accessions	Q8WWK9, Q3KRA5, Q5VXB4, Q8IWV5, Q8IWV6, Q96FH9, Q9H012, Q9H0D0, Q9H988, Q9HC49, Q9NVG4	Gene names	CKAP2, LB1, TMAP
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 2 (Tumor-associated microtubule- associated protein) (CTCL tumor antigen se20-10).

HELI_MOUSE
θ value	5.27518 (rank : 202)	NC score	-0.007365 (rank : 299)
Query Neighborhood Hits	253	Target Neighborhood Hits	746	Shared Neighborhood Hits	8
SwissProt Accessions	P81183	Gene names	Ikzf2, Helios, Zfpn1a2, Znfn1a2
Domain Architecture	No domain graphic available
Description	Zinc finger protein Helios (IKAROS family zinc finger protein 2).

ITSN2_MOUSE
θ value	5.27518 (rank : 203)	NC score	0.133630 (rank : 122)
Query Neighborhood Hits	253	Target Neighborhood Hits	1371	Shared Neighborhood Hits	98
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

JHD1B_MOUSE
θ value	5.27518 (rank : 204)	NC score	0.007423 (rank : 279)
Query Neighborhood Hits	253	Target Neighborhood Hits	214	Shared Neighborhood Hits	18
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

MAP2_MOUSE
θ value	5.27518 (rank : 205)	NC score	0.027920 (rank : 207)
Query Neighborhood Hits	253	Target Neighborhood Hits	342	Shared Neighborhood Hits	31
SwissProt Accessions	P20357	Gene names	Map2, Mtap2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2).

MAP9_MOUSE
θ value	5.27518 (rank : 206)	NC score	0.019646 (rank : 231)
Query Neighborhood Hits	253	Target Neighborhood Hits	529	Shared Neighborhood Hits	39
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

MDN1_HUMAN
θ value	5.27518 (rank : 207)	NC score	0.042626 (rank : 182)
Query Neighborhood Hits	253	Target Neighborhood Hits	662	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

NUPL2_HUMAN
θ value	5.27518 (rank : 208)	NC score	0.011865 (rank : 258)
Query Neighborhood Hits	253	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	O15504, Q49AE7, Q9BS49	Gene names	NUPL2, CG1
Domain Architecture	No domain graphic available
Description	Nucleoporin-like 2 (NLP-1) (hCG1) (NUP42 homolog).

S3TC1_HUMAN
θ value	5.27518 (rank : 209)	NC score	0.013113 (rank : 253)
Query Neighborhood Hits	253	Target Neighborhood Hits	78	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TE82	Gene names	SH3TC1
Domain Architecture	No domain graphic available
Description	SH3 domain and tetratricopeptide repeats-containing protein 1.

UBF1_HUMAN
θ value	5.27518 (rank : 210)	NC score	0.018083 (rank : 237)
Query Neighborhood Hits	253	Target Neighborhood Hits	415	Shared Neighborhood Hits	34
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

UBP2L_HUMAN
θ value	5.27518 (rank : 211)	NC score	0.023955 (rank : 212)
Query Neighborhood Hits	253	Target Neighborhood Hits	170	Shared Neighborhood Hits	14
SwissProt Accessions	Q14157, Q5VU75, Q5VU76, Q9BTU3, Q9UGL5	Gene names	UBAP2L, KIAA0144, NICE4
Domain Architecture
Description	Ubiquitin-associated protein 2-like (Protein NICE-4).

UBP2L_MOUSE
θ value	5.27518 (rank : 212)	NC score	0.022609 (rank : 220)
Query Neighborhood Hits	253	Target Neighborhood Hits	173	Shared Neighborhood Hits	15
SwissProt Accessions	Q80X50, Q8BIT6, Q8BIW4, Q8BJ01, Q8CIG7, Q8K102, Q9CRT6	Gene names	Ubap2l
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated protein 2-like.

UBP8_HUMAN
θ value	5.27518 (rank : 213)	NC score	0.008540 (rank : 272)
Query Neighborhood Hits	253	Target Neighborhood Hits	751	Shared Neighborhood Hits	36
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

WWP1_HUMAN
θ value	5.27518 (rank : 214)	NC score	0.053967 (rank : 163)
Query Neighborhood Hits	253	Target Neighborhood Hits	262	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

ADA30_HUMAN
θ value	6.88961 (rank : 215)	NC score	0.002016 (rank : 295)
Query Neighborhood Hits	253	Target Neighborhood Hits	391	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

ASPM_HUMAN
θ value	6.88961 (rank : 216)	NC score	0.007223 (rank : 281)
Query Neighborhood Hits	253	Target Neighborhood Hits	197	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IZT6, Q86UX4, Q8IUL2, Q8IZJ7, Q8IZJ8, Q8IZJ9, Q8N4D1, Q9NVS1, Q9NVT6	Gene names	ASPM, MCPH5
Domain Architecture
Description	Abnormal spindle-like microcephaly-associated protein (Abnormal spindle protein homolog) (Asp homolog).

ASXL1_HUMAN
θ value	6.88961 (rank : 217)	NC score	0.031861 (rank : 201)
Query Neighborhood Hits	253	Target Neighborhood Hits	260	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

BAIP3_MOUSE
θ value	6.88961 (rank : 218)	NC score	0.403186 (rank : 68)
Query Neighborhood Hits	253	Target Neighborhood Hits	112	Shared Neighborhood Hits	88
SwissProt Accessions	Q80TT2, Q6RUT4	Gene names	Baiap3, Gm937, Kiaa0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

DNMT1_HUMAN
θ value	6.88961 (rank : 219)	NC score	0.023685 (rank : 217)
Query Neighborhood Hits	253	Target Neighborhood Hits	401	Shared Neighborhood Hits	43
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

FGD6_HUMAN
θ value	6.88961 (rank : 220)	NC score	0.011726 (rank : 260)
Query Neighborhood Hits	253	Target Neighborhood Hits	237	Shared Neighborhood Hits	16
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

GPTC2_MOUSE
θ value	6.88961 (rank : 221)	NC score	0.008580 (rank : 271)
Query Neighborhood Hits	253	Target Neighborhood Hits	61	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TQC7, Q8BNJ9, Q8BPM1, Q8CDH9	Gene names	Gpatc2
Domain Architecture
Description	G patch domain-containing protein 2.

HES6_HUMAN
θ value	6.88961 (rank : 222)	NC score	0.010132 (rank : 265)
Query Neighborhood Hits	253	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q96HZ4, Q8N2J2, Q96T93, Q9P2S3	Gene names	HES6
Domain Architecture	No domain graphic available
Description	Transcription cofactor HES-6 (Hairy and enhancer of split 6) (C- HAIRY1).

HES6_MOUSE
θ value	6.88961 (rank : 223)	NC score	0.010220 (rank : 264)
Query Neighborhood Hits	253	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JHE6, Q3U2D7	Gene names	Hes6
Domain Architecture	No domain graphic available
Description	Transcription cofactor HES-6 (Hairy and enhancer of split 6).

LAT_HUMAN
θ value	6.88961 (rank : 224)	NC score	0.012648 (rank : 256)
Query Neighborhood Hits	253	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	O43561, O43919	Gene names	LAT
Domain Architecture	No domain graphic available
Description	Linker for activation of T-cells family member 1 (36 kDa phospho- tyrosine adapter protein) (pp36) (p36-38).

MLL3_HUMAN
θ value	6.88961 (rank : 225)	NC score	0.020522 (rank : 225)
Query Neighborhood Hits	253	Target Neighborhood Hits	1644	Shared Neighborhood Hits	63
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

OGFR_MOUSE
θ value	6.88961 (rank : 226)	NC score	0.028934 (rank : 205)
Query Neighborhood Hits	253	Target Neighborhood Hits	584	Shared Neighborhood Hits	38
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

SOS1_HUMAN
θ value	6.88961 (rank : 227)	NC score	0.007736 (rank : 274)
Query Neighborhood Hits	253	Target Neighborhood Hits	274	Shared Neighborhood Hits	11
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

SSBP4_HUMAN
θ value	6.88961 (rank : 228)	NC score	0.013565 (rank : 252)
Query Neighborhood Hits	253	Target Neighborhood Hits	753	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

TS1R2_HUMAN
θ value	6.88961 (rank : 229)	NC score	0.002255 (rank : 294)
Query Neighborhood Hits	253	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TE23, Q5TZ19	Gene names	TAS1R2, GPR71, T1R2, TR2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).

UB2J1_HUMAN
θ value	6.88961 (rank : 230)	NC score	0.004306 (rank : 289)
Query Neighborhood Hits	253	Target Neighborhood Hits	61	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y385, Q5W0N4, Q9BZ32, Q9NQL3, Q9NY66, Q9P011, Q9P0S0, Q9UF10	Gene names	UBE2J1, NCUBE1
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 J1 (EC 6.3.2.19) (Non-canonical ubiquitin-conjugating enzyme 1) (NCUBE1) (Yeast ubiquitin-conjugating enzyme UBC6 homolog E) (HSUBC6e).

AAKG2_MOUSE
θ value	8.99809 (rank : 231)	NC score	0.005889 (rank : 286)
Query Neighborhood Hits	253	Target Neighborhood Hits	53	Shared Neighborhood Hits	7
SwissProt Accessions	Q91WG5, Q6V7V5	Gene names	Prkag2
Domain Architecture	No domain graphic available
Description	5'-AMP-activated protein kinase subunit gamma-2 (AMPK gamma-2 chain) (AMPK gamma2).

AUTS2_HUMAN
θ value	8.99809 (rank : 232)	NC score	0.030299 (rank : 203)
Query Neighborhood Hits	253	Target Neighborhood Hits	342	Shared Neighborhood Hits	31
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

B3A2_HUMAN
θ value	8.99809 (rank : 233)	NC score	0.003524 (rank : 293)
Query Neighborhood Hits	253	Target Neighborhood Hits	57	Shared Neighborhood Hits	6
SwissProt Accessions	P04920, Q45EY5, Q969L3	Gene names	SLC4A2, AE2, EPB3L1, HKB3, MPB3L
Domain Architecture
Description	Anion exchange protein 2 (Non-erythroid band 3-like protein) (AE2 anion exchanger) (Solute carrier family 4 member 2) (BND3L).

BAIP3_HUMAN
θ value	8.99809 (rank : 234)	NC score	0.404498 (rank : 67)
Query Neighborhood Hits	253	Target Neighborhood Hits	108	Shared Neighborhood Hits	83
SwissProt Accessions	O94812, O94839, Q2M226, Q658J2, Q76N05, Q96RZ3, Q9UJK1	Gene names	BAIAP3, KIAA0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

CEP68_MOUSE
θ value	8.99809 (rank : 235)	NC score	0.008026 (rank : 273)
Query Neighborhood Hits	253	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C0D9, Q3US49, Q5SW85, Q8R2V0	Gene names	Cep68
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 68 kDa (Cep68 protein).

GCC2_MOUSE
θ value	8.99809 (rank : 236)	NC score	0.003975 (rank : 290)
Query Neighborhood Hits	253	Target Neighborhood Hits	1619	Shared Neighborhood Hits	42
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

ILDR1_HUMAN
θ value	8.99809 (rank : 237)	NC score	0.007476 (rank : 277)
Query Neighborhood Hits	253	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q86SU0, Q6ZP61, Q7Z578	Gene names	ILDR1
Domain Architecture	No domain graphic available
Description	Immunoglobulin-like domain-containing receptor 1 precursor.

KCNB2_HUMAN
θ value	8.99809 (rank : 238)	NC score	0.000479 (rank : 296)
Query Neighborhood Hits	253	Target Neighborhood Hits	212	Shared Neighborhood Hits	7
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

LRC50_HUMAN
θ value	8.99809 (rank : 239)	NC score	0.007521 (rank : 275)
Query Neighborhood Hits	253	Target Neighborhood Hits	275	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NEP3, Q69YI8, Q69YJ0, Q96LP3	Gene names	LRRC50
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 50.

MADCA_HUMAN
θ value	8.99809 (rank : 240)	NC score	0.024391 (rank : 211)
Query Neighborhood Hits	253	Target Neighborhood Hits	221	Shared Neighborhood Hits	16
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

MAP2_HUMAN
θ value	8.99809 (rank : 241)	NC score	0.022629 (rank : 219)
Query Neighborhood Hits	253	Target Neighborhood Hits	348	Shared Neighborhood Hits	26
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

MYPT1_MOUSE
θ value	8.99809 (rank : 242)	NC score	0.008736 (rank : 270)
Query Neighborhood Hits	253	Target Neighborhood Hits	539	Shared Neighborhood Hits	30
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

NFM_MOUSE
θ value	8.99809 (rank : 243)	NC score	0.011641 (rank : 261)
Query Neighborhood Hits	253	Target Neighborhood Hits	1159	Shared Neighborhood Hits	64
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

NSD1_MOUSE
θ value	8.99809 (rank : 244)	NC score	0.015612 (rank : 249)
Query Neighborhood Hits	253	Target Neighborhood Hits	472	Shared Neighborhood Hits	32
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

OSBL5_HUMAN
θ value	8.99809 (rank : 245)	NC score	0.003629 (rank : 292)
Query Neighborhood Hits	253	Target Neighborhood Hits	117	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H0X9, Q9BZB0, Q9P1Z4	Gene names	OSBPL5, KIAA1534, ORP5
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5).

PA24E_HUMAN
θ value	8.99809 (rank : 246)	NC score	0.168366 (rank : 110)
Query Neighborhood Hits	253	Target Neighborhood Hits	89	Shared Neighborhood Hits	69
SwissProt Accessions	Q3MJ16, Q6ZSC0	Gene names	PLA2G4E
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

PCIF1_HUMAN
θ value	8.99809 (rank : 247)	NC score	0.005983 (rank : 284)
Query Neighborhood Hits	253	Target Neighborhood Hits	92	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H4Z3, Q9NT85	Gene names	PCIF1, C20orf67
Domain Architecture
Description	Phosphorylated CTD-interacting factor 1.

PTPRG_MOUSE
θ value	8.99809 (rank : 248)	NC score	0.003778 (rank : 291)
Query Neighborhood Hits	253	Target Neighborhood Hits	260	Shared Neighborhood Hits	19
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

SUHW1_HUMAN
θ value	8.99809 (rank : 249)	NC score	-0.004366 (rank : 298)
Query Neighborhood Hits	253	Target Neighborhood Hits	648	Shared Neighborhood Hits	8
SwissProt Accessions	P59817	Gene names	SUHW1
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 1 (3'OY11.1).

TM16H_HUMAN
θ value	8.99809 (rank : 250)	NC score	0.011855 (rank : 259)
Query Neighborhood Hits	253	Target Neighborhood Hits	139	Shared Neighborhood Hits	9
SwissProt Accessions	Q9HCE9	Gene names	TMEM16H, KIAA1623
Domain Architecture	No domain graphic available
Description	Transmembrane protein 16H.

TOX_HUMAN
θ value	8.99809 (rank : 251)	NC score	0.005761 (rank : 288)
Query Neighborhood Hits	253	Target Neighborhood Hits	106	Shared Neighborhood Hits	7
SwissProt Accessions	O94900, Q96AV5	Gene names	TOX, KIAA0808
Domain Architecture	No domain graphic available
Description	Thymus high mobility group box protein TOX.

TXLNB_HUMAN
θ value	8.99809 (rank : 252)	NC score	0.006910 (rank : 282)
Query Neighborhood Hits	253	Target Neighborhood Hits	912	Shared Neighborhood Hits	42
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

WNK4_MOUSE
θ value	8.99809 (rank : 253)	NC score	0.009541 (rank : 266)
Query Neighborhood Hits	253	Target Neighborhood Hits	961	Shared Neighborhood Hits	22
SwissProt Accessions	Q80UE6, Q4VAC1, Q80XB5, Q80XN2, Q8R0N0, Q8R340	Gene names	Wnk4, Prkwnk4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

BASP_HUMAN
θ value	θ > 10 (rank : 254)	NC score	0.064167 (rank : 145)
Query Neighborhood Hits	253	Target Neighborhood Hits	321	Shared Neighborhood Hits	28
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BSN_HUMAN
θ value	θ > 10 (rank : 255)	NC score	0.061637 (rank : 147)
Query Neighborhood Hits	253	Target Neighborhood Hits	1537	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

BSN_MOUSE
θ value	θ > 10 (rank : 256)	NC score	0.059937 (rank : 149)
Query Neighborhood Hits	253	Target Neighborhood Hits	2057	Shared Neighborhood Hits	65
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CPNE1_HUMAN
θ value	θ > 10 (rank : 257)	NC score	0.126829 (rank : 123)
Query Neighborhood Hits	253	Target Neighborhood Hits	70	Shared Neighborhood Hits	56
SwissProt Accessions	Q99829, Q6IBL3, Q9H243, Q9NTZ7	Gene names	CPNE1, CPN1
Domain Architecture
Description	Copine-1 (Copine I).

CPNE1_MOUSE
θ value	θ > 10 (rank : 258)	NC score	0.149843 (rank : 120)
Query Neighborhood Hits	253	Target Neighborhood Hits	83	Shared Neighborhood Hits	61
SwissProt Accessions	Q8C166, Q925K4, Q925K5	Gene names	Cpne1
Domain Architecture
Description	Copine-1 (Copine I).

CPNE2_HUMAN
θ value	θ > 10 (rank : 259)	NC score	0.148638 (rank : 121)
Query Neighborhood Hits	253	Target Neighborhood Hits	75	Shared Neighborhood Hits	56
SwissProt Accessions	Q96FN4, Q68D19, Q86XP9	Gene names	CPNE2
Domain Architecture
Description	Copine-2 (Copine II).

CPNE2_MOUSE
θ value	θ > 10 (rank : 260)	NC score	0.150236 (rank : 118)
Query Neighborhood Hits	253	Target Neighborhood Hits	82	Shared Neighborhood Hits	59
SwissProt Accessions	P59108, Q8K1D7	Gene names	Cpne2
Domain Architecture
Description	Copine-2 (Copine II).

CPNE3_HUMAN
θ value	θ > 10 (rank : 261)	NC score	0.172657 (rank : 107)
Query Neighborhood Hits	253	Target Neighborhood Hits	90	Shared Neighborhood Hits	64
SwissProt Accessions	O75131, Q8IYA1	Gene names	CPNE3, CPN3, KIAA0636
Domain Architecture
Description	Copine-3 (Copine III).

CPNE3_MOUSE
θ value	θ > 10 (rank : 262)	NC score	0.172602 (rank : 108)
Query Neighborhood Hits	253	Target Neighborhood Hits	90	Shared Neighborhood Hits	66
SwissProt Accessions	Q8BT60, Q5CZX9, Q5DU22	Gene names	Cpne3, Kiaa0636
Domain Architecture
Description	Copine-3 (Copine III).

CPNE4_HUMAN
θ value	θ > 10 (rank : 263)	NC score	0.100952 (rank : 135)
Query Neighborhood Hits	253	Target Neighborhood Hits	70	Shared Neighborhood Hits	52
SwissProt Accessions	Q96A23, Q8TEX1	Gene names	CPNE4
Domain Architecture
Description	Copine-4 (Copine IV) (Copine-8).

CPNE4_MOUSE
θ value	θ > 10 (rank : 264)	NC score	0.097461 (rank : 136)
Query Neighborhood Hits	253	Target Neighborhood Hits	67	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BLR2	Gene names	Cpne4
Domain Architecture	No domain graphic available
Description	Copine-4 (Copine IV).

CPNE6_HUMAN
θ value	θ > 10 (rank : 265)	NC score	0.112954 (rank : 125)
Query Neighborhood Hits	253	Target Neighborhood Hits	85	Shared Neighborhood Hits	58
SwissProt Accessions	O95741, Q53HA6, Q8WVG1	Gene names	CPNE6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

CPNE6_MOUSE
θ value	θ > 10 (rank : 266)	NC score	0.111664 (rank : 127)
Query Neighborhood Hits	253	Target Neighborhood Hits	87	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Z140	Gene names	Cpne6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

DAB2P_HUMAN
θ value	θ > 10 (rank : 267)	NC score	0.059438 (rank : 150)
Query Neighborhood Hits	253	Target Neighborhood Hits	303	Shared Neighborhood Hits	18
SwissProt Accessions	Q5VWQ8, Q8TDL2, Q96SE1, Q9C0C0	Gene names	DAB2IP, AF9Q34, AIP1, KIAA1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein) (DAB2 interaction protein) (ASK-interacting protein 1).

DAB2P_MOUSE
θ value	θ > 10 (rank : 268)	NC score	0.057065 (rank : 156)
Query Neighborhood Hits	253	Target Neighborhood Hits	284	Shared Neighborhood Hits	16
SwissProt Accessions	Q3UHC7, Q3TPD5, Q3UH44, Q6JTV1, Q80T97	Gene names	Dab2ip, Kiaa1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein).

PA24A_HUMAN
θ value	θ > 10 (rank : 269)	NC score	0.158103 (rank : 115)
Query Neighborhood Hits	253	Target Neighborhood Hits	88	Shared Neighborhood Hits	70
SwissProt Accessions	P47712	Gene names	PLA2G4A, CPLA2, PLA2G4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

PA24A_MOUSE
θ value	θ > 10 (rank : 270)	NC score	0.170626 (rank : 109)
Query Neighborhood Hits	253	Target Neighborhood Hits	100	Shared Neighborhood Hits	71
SwissProt Accessions	P47713	Gene names	Pla2g4a, Cpla2, Pla2g4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

PA24B_HUMAN
θ value	θ > 10 (rank : 271)	NC score	0.160105 (rank : 114)
Query Neighborhood Hits	253	Target Neighborhood Hits	89	Shared Neighborhood Hits	63
SwissProt Accessions	O95712, Q59GF9, Q8TB10, Q9UKV7	Gene names	PLA2G4B
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

PA24B_MOUSE
θ value	θ > 10 (rank : 272)	NC score	0.201381 (rank : 97)
Query Neighborhood Hits	253	Target Neighborhood Hits	102	Shared Neighborhood Hits	69
SwissProt Accessions	Q4QQM1, Q80VV8, Q91W88	Gene names	Pla2g4b
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

PA24E_MOUSE
θ value	θ > 10 (rank : 273)	NC score	0.186690 (rank : 104)
Query Neighborhood Hits	253	Target Neighborhood Hits	95	Shared Neighborhood Hits	74
SwissProt Accessions	Q50L42, Q8BX44	Gene names	Pla2g4e
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

PA24F_HUMAN
θ value	θ > 10 (rank : 274)	NC score	0.106141 (rank : 131)
Query Neighborhood Hits	253	Target Neighborhood Hits	78	Shared Neighborhood Hits	57
SwissProt Accessions	Q68DD2, Q6ZMC8	Gene names	PLA2G4F
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

PA24F_MOUSE
θ value	θ > 10 (rank : 275)	NC score	0.125306 (rank : 124)
Query Neighborhood Hits	253	Target Neighborhood Hits	93	Shared Neighborhood Hits	59
SwissProt Accessions	Q50L41, Q80VQ8, Q80VV9	Gene names	Pla2g4f
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

PK3CA_HUMAN
θ value	θ > 10 (rank : 276)	NC score	0.055376 (rank : 161)
Query Neighborhood Hits	253	Target Neighborhood Hits	45	Shared Neighborhood Hits	7
SwissProt Accessions	P42336, Q99762	Gene names	PIK3CA
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).

PK3CA_MOUSE
θ value	θ > 10 (rank : 277)	NC score	0.055302 (rank : 162)
Query Neighborhood Hits	253	Target Neighborhood Hits	48	Shared Neighborhood Hits	5
SwissProt Accessions	P42337	Gene names	Pik3ca
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).

PK3CB_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.052253 (rank : 169)
Query Neighborhood Hits	253	Target Neighborhood Hits	43	Shared Neighborhood Hits	5
SwissProt Accessions	P42338	Gene names	PIK3CB
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).

PK3CB_MOUSE
θ value	θ > 10 (rank : 279)	NC score	0.052276 (rank : 168)
Query Neighborhood Hits	253	Target Neighborhood Hits	49	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BTI9	Gene names	Pik3cb
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).

PK3CD_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.052784 (rank : 166)
Query Neighborhood Hits	253	Target Neighborhood Hits	40	Shared Neighborhood Hits	5
SwissProt Accessions	O00329, O15445	Gene names	PIK3CD
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit delta) (PtdIns-3- kinase p110) (PI3K) (p110delta).

PK3CD_MOUSE
θ value	θ > 10 (rank : 281)	NC score	0.052720 (rank : 167)
Query Neighborhood Hits	253	Target Neighborhood Hits	42	Shared Neighborhood Hits	5
SwissProt Accessions	O35904	Gene names	Pik3cd
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit delta) (PtdIns-3- kinase p110) (PI3K) (p110delta).

PK3CG_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.056864 (rank : 157)
Query Neighborhood Hits	253	Target Neighborhood Hits	41	Shared Neighborhood Hits	5
SwissProt Accessions	P48736, Q8IV23, Q9BZC8	Gene names	PIK3CG
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

PK3CG_MOUSE
θ value	θ > 10 (rank : 283)	NC score	0.056707 (rank : 158)
Query Neighborhood Hits	253	Target Neighborhood Hits	43	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JHG7	Gene names	Pik3cg, Pi3kg1
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

PLCD1_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.112644 (rank : 126)
Query Neighborhood Hits	253	Target Neighborhood Hits	93	Shared Neighborhood Hits	50
SwissProt Accessions	P51178	Gene names	PLCD1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

PLCD1_MOUSE
θ value	θ > 10 (rank : 285)	NC score	0.075581 (rank : 139)
Query Neighborhood Hits	253	Target Neighborhood Hits	106	Shared Neighborhood Hits	49
SwissProt Accessions	Q8R3B1	Gene names	Plcd1, Plcd
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

RASA1_HUMAN
θ value	θ > 10 (rank : 286)	NC score	0.066748 (rank : 143)
Query Neighborhood Hits	253	Target Neighborhood Hits	258	Shared Neighborhood Hits	25
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

RIMS3_HUMAN
θ value	θ > 10 (rank : 287)	NC score	0.386532 (rank : 69)
Query Neighborhood Hits	253	Target Neighborhood Hits	66	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UJD0, Q92511	Gene names	RIMS3, KIAA0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

RIMS3_MOUSE
θ value	θ > 10 (rank : 288)	NC score	0.384361 (rank : 70)
Query Neighborhood Hits	253	Target Neighborhood Hits	67	Shared Neighborhood Hits	64
SwissProt Accessions	Q80U57	Gene names	Rims3, Kiaa0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

SMUF1_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.106886 (rank : 130)
Query Neighborhood Hits	253	Target Neighborhood Hits	135	Shared Neighborhood Hits	57
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

SMUF1_MOUSE
θ value	θ > 10 (rank : 290)	NC score	0.105729 (rank : 132)
Query Neighborhood Hits	253	Target Neighborhood Hits	142	Shared Neighborhood Hits	57
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

SMUF2_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.105667 (rank : 133)
Query Neighborhood Hits	253	Target Neighborhood Hits	142	Shared Neighborhood Hits	59
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

SYT8_HUMAN
θ value	θ > 10 (rank : 292)	NC score	0.076621 (rank : 138)
Query Neighborhood Hits	253	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NBV8, Q9NSV9	Gene names	SYT8
Domain Architecture	No domain graphic available
Description	Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII).

TAC2N_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.281605 (rank : 85)
Query Neighborhood Hits	253	Target Neighborhood Hits	47	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N9U0	Gene names	MTAC2D1, C14orf47
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

TAC2N_MOUSE
θ value	θ > 10 (rank : 294)	NC score	0.280643 (rank : 86)
Query Neighborhood Hits	253	Target Neighborhood Hits	43	Shared Neighborhood Hits	36
SwissProt Accessions	Q91XT6, Q9D4A0	Gene names	Mtac2d1
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

TGON2_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.053097 (rank : 164)
Query Neighborhood Hits	253	Target Neighborhood Hits	1037	Shared Neighborhood Hits	74
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TXND2_MOUSE
θ value	θ > 10 (rank : 296)	NC score	0.050916 (rank : 170)
Query Neighborhood Hits	253	Target Neighborhood Hits	828	Shared Neighborhood Hits	69
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

WWC1_HUMAN
θ value	θ > 10 (rank : 297)	NC score	0.078746 (rank : 137)
Query Neighborhood Hits	253	Target Neighborhood Hits	290	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

WWC1_MOUSE
θ value	θ > 10 (rank : 298)	NC score	0.107529 (rank : 128)
Query Neighborhood Hits	253	Target Neighborhood Hits	290	Shared Neighborhood Hits	37
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

WWP1_MOUSE
θ value	θ > 10 (rank : 299)	NC score	0.050050 (rank : 171)
Query Neighborhood Hits	253	Target Neighborhood Hits	138	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

Hits sorted by NC score

SYTL2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	253	Target Neighborhood Hits	253	Shared Neighborhood Hits	253
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

SYTL2_HUMAN
NC score	0.976074 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	253	Target Neighborhood Hits	248	Shared Neighborhood Hits	121
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

SYTL1_HUMAN
NC score	0.931509 (rank : 3)	θ value	3.22841e-82 (rank : 3)
Query Neighborhood Hits	253	Target Neighborhood Hits	227	Shared Neighborhood Hits	108
SwissProt Accessions	Q8IYJ3, Q96BB6, Q96GU6, Q96S89, Q96SI0	Gene names	SYTL1, SLP1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1) (SB146).

SYTL4_HUMAN
NC score	0.924191 (rank : 4)	θ value	1.22964e-73 (rank : 6)
Query Neighborhood Hits	253	Target Neighborhood Hits	138	Shared Neighborhood Hits	99
SwissProt Accessions	Q96C24, Q5H9J3, Q5JPG8, Q8N9P4, Q9H4R0, Q9H4R1	Gene names	SYTL4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

SYTL4_MOUSE
NC score	0.923772 (rank : 5)	θ value	3.45727e-76 (rank : 5)
Query Neighborhood Hits	253	Target Neighborhood Hits	137	Shared Neighborhood Hits	101
SwissProt Accessions	Q9R0Q1, Q8R321, Q9R0Q0	Gene names	Sytl4, Slp4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

SYTL1_MOUSE
NC score	0.919444 (rank : 6)	θ value	5.15425e-80 (rank : 4)
Query Neighborhood Hits	253	Target Neighborhood Hits	314	Shared Neighborhood Hits	109
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

SYTL5_MOUSE
NC score	0.916724 (rank : 7)	θ value	1.07972e-61 (rank : 8)
Query Neighborhood Hits	253	Target Neighborhood Hits	154	Shared Neighborhood Hits	105
SwissProt Accessions	Q80T23, Q812E5	Gene names	Sytl5, Slp5
Domain Architecture
Description	Synaptotagmin-like protein 5.

SYTL5_HUMAN
NC score	0.915316 (rank : 8)	θ value	1.40689e-69 (rank : 7)
Query Neighborhood Hits	253	Target Neighborhood Hits	237	Shared Neighborhood Hits	121
SwissProt Accessions	Q8TDW5	Gene names	SYTL5, SLP5
Domain Architecture
Description	Synaptotagmin-like protein 5.

SYTL3_MOUSE
NC score	0.908288 (rank : 9)	θ value	1.91031e-50 (rank : 9)
Query Neighborhood Hits	253	Target Neighborhood Hits	110	Shared Neighborhood Hits	87
SwissProt Accessions	Q99N48, Q8C506, Q99N47, Q99N49, Q99N54, Q99N79	Gene names	Sytl3, Slp3
Domain Architecture
Description	Synaptotagmin-like protein 3 (Exophilin-6).

DOC2B_MOUSE
NC score	0.795708 (rank : 10)	θ value	9.24701e-21 (rank : 14)
Query Neighborhood Hits	253	Target Neighborhood Hits	169	Shared Neighborhood Hits	106
SwissProt Accessions	P70169, Q6NXK3	Gene names	Doc2b
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

SYT3_HUMAN
NC score	0.794554 (rank : 11)	θ value	5.23862e-24 (rank : 10)
Query Neighborhood Hits	253	Target Neighborhood Hits	145	Shared Neighborhood Hits	105
SwissProt Accessions	Q9BQG1, Q8N5Z1, Q8N640	Gene names	SYT3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

SYT3_MOUSE
NC score	0.794179 (rank : 12)	θ value	7.56453e-23 (rank : 11)
Query Neighborhood Hits	253	Target Neighborhood Hits	147	Shared Neighborhood Hits	104
SwissProt Accessions	O35681, P97791, Q80WV1	Gene names	Syt3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

DOC2B_HUMAN
NC score	0.794141 (rank : 13)	θ value	1.02238e-19 (rank : 18)
Query Neighborhood Hits	253	Target Neighborhood Hits	150	Shared Neighborhood Hits	104
SwissProt Accessions	Q14184	Gene names	DOC2B
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

DOC2A_MOUSE
NC score	0.792565 (rank : 14)	θ value	3.40345e-15 (rank : 35)
Query Neighborhood Hits	253	Target Neighborhood Hits	140	Shared Neighborhood Hits	101
SwissProt Accessions	Q7TNF0	Gene names	Doc2a
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha).

DOC2A_HUMAN
NC score	0.791535 (rank : 15)	θ value	1.99529e-15 (rank : 32)
Query Neighborhood Hits	253	Target Neighborhood Hits	144	Shared Neighborhood Hits	102
SwissProt Accessions	Q14183, Q6P4G4, Q7Z5G0, Q8IVX0	Gene names	DOC2A
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha) (Doc2).

SYT2_MOUSE
NC score	0.789003 (rank : 16)	θ value	9.24701e-21 (rank : 15)
Query Neighborhood Hits	253	Target Neighborhood Hits	143	Shared Neighborhood Hits	105
SwissProt Accessions	P46097, Q8R0E1	Gene names	Syt2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT2_HUMAN
NC score	0.788950 (rank : 17)	θ value	1.2077e-20 (rank : 16)
Query Neighborhood Hits	253	Target Neighborhood Hits	142	Shared Neighborhood Hits	105
SwissProt Accessions	Q8N9I0, Q496K5, Q8NBE5	Gene names	SYT2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT5_MOUSE
NC score	0.786213 (rank : 18)	θ value	2.60593e-15 (rank : 34)
Query Neighborhood Hits	253	Target Neighborhood Hits	140	Shared Neighborhood Hits	105
SwissProt Accessions	Q9R0N5	Gene names	Syt5, Syt9
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV) (Synaptotagmin IX).

SYT5_HUMAN
NC score	0.785910 (rank : 19)	θ value	8.95645e-16 (rank : 31)
Query Neighborhood Hits	253	Target Neighborhood Hits	138	Shared Neighborhood Hits	105
SwissProt Accessions	O00445, Q86X72	Gene names	SYT5
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV).

SYT6_MOUSE
NC score	0.781169 (rank : 20)	θ value	2.20094e-22 (rank : 12)
Query Neighborhood Hits	253	Target Neighborhood Hits	132	Shared Neighborhood Hits	102
SwissProt Accessions	Q9R0N8	Gene names	Syt6
Domain Architecture
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

SYT7_MOUSE
NC score	0.781081 (rank : 21)	θ value	1.09485e-13 (rank : 36)
Query Neighborhood Hits	253	Target Neighborhood Hits	137	Shared Neighborhood Hits	104
SwissProt Accessions	Q9R0N7	Gene names	Syt7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

SYT1_HUMAN
NC score	0.780910 (rank : 22)	θ value	9.56915e-18 (rank : 24)
Query Neighborhood Hits	253	Target Neighborhood Hits	150	Shared Neighborhood Hits	105
SwissProt Accessions	P21579	Gene names	SYT1, SYT
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT1_MOUSE
NC score	0.780887 (rank : 23)	θ value	9.56915e-18 (rank : 25)
Query Neighborhood Hits	253	Target Neighborhood Hits	150	Shared Neighborhood Hits	105
SwissProt Accessions	P46096	Gene names	Syt1
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT7_HUMAN
NC score	0.780726 (rank : 24)	θ value	7.09661e-13 (rank : 37)
Query Neighborhood Hits	253	Target Neighborhood Hits	137	Shared Neighborhood Hits	104
SwissProt Accessions	O43581	Gene names	SYT7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

SYT6_HUMAN
NC score	0.780223 (rank : 25)	θ value	6.40375e-22 (rank : 13)
Query Neighborhood Hits	253	Target Neighborhood Hits	138	Shared Neighborhood Hits	102
SwissProt Accessions	Q5T7P8	Gene names	SYT6
Domain Architecture	No domain graphic available
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

RP3A_HUMAN
NC score	0.777267 (rank : 26)	θ value	1.33526e-19 (rank : 19)
Query Neighborhood Hits	253	Target Neighborhood Hits	305	Shared Neighborhood Hits	115
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SYT10_HUMAN
NC score	0.776082 (rank : 27)	θ value	5.07402e-19 (rank : 22)
Query Neighborhood Hits	253	Target Neighborhood Hits	134	Shared Neighborhood Hits	102
SwissProt Accessions	Q6XYQ8	Gene names	SYT10
Domain Architecture	No domain graphic available
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

SYT11_MOUSE
NC score	0.775757 (rank : 28)	θ value	2.27762e-19 (rank : 21)
Query Neighborhood Hits	253	Target Neighborhood Hits	116	Shared Neighborhood Hits	99
SwissProt Accessions	Q9R0N3	Gene names	Syt11
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

SYT11_HUMAN
NC score	0.775160 (rank : 29)	θ value	2.27762e-19 (rank : 20)
Query Neighborhood Hits	253	Target Neighborhood Hits	113	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BT88, Q14998, Q68CT5, Q8IXU3, Q96SU2	Gene names	SYT11, KIAA0080
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

SYT10_MOUSE
NC score	0.773120 (rank : 30)	θ value	8.65492e-19 (rank : 23)
Query Neighborhood Hits	253	Target Neighborhood Hits	133	Shared Neighborhood Hits	103
SwissProt Accessions	Q9R0N4	Gene names	Syt10
Domain Architecture
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

RP3A_MOUSE
NC score	0.772763 (rank : 31)	θ value	1.5773e-20 (rank : 17)
Query Neighborhood Hits	253	Target Neighborhood Hits	510	Shared Neighborhood Hits	126
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SYT9_HUMAN
NC score	0.772577 (rank : 32)	θ value	2.7842e-17 (rank : 26)
Query Neighborhood Hits	253	Target Neighborhood Hits	144	Shared Neighborhood Hits	103
SwissProt Accessions	Q86SS6	Gene names	SYT9
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX).

SYT9_MOUSE
NC score	0.770927 (rank : 33)	θ value	2.7842e-17 (rank : 27)
Query Neighborhood Hits	253	Target Neighborhood Hits	148	Shared Neighborhood Hits	104
SwissProt Accessions	Q9R0N9, Q8C280	Gene names	Syt9, Syt5
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX) (Synaptotagmin V).

SYT4_HUMAN
NC score	0.770449 (rank : 34)	θ value	2.35696e-16 (rank : 29)
Query Neighborhood Hits	253	Target Neighborhood Hits	121	Shared Neighborhood Hits	100
SwissProt Accessions	Q9H2B2, Q9P2K4	Gene names	SYT4, KIAA1342
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

SYT4_MOUSE
NC score	0.768302 (rank : 35)	θ value	2.35696e-16 (rank : 30)
Query Neighborhood Hits	253	Target Neighborhood Hits	123	Shared Neighborhood Hits	98
SwissProt Accessions	P40749, Q3UFC1, Q8BGH3, Q8BRL6	Gene names	Syt4, Syt3
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

DOC2G_MOUSE
NC score	0.763108 (rank : 36)	θ value	1.133e-10 (rank : 40)
Query Neighborhood Hits	253	Target Neighborhood Hits	125	Shared Neighborhood Hits	97
SwissProt Accessions	Q9ESN1, Q6P8R8	Gene names	Doc2g
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein gamma (Doc2-gamma).

SYT12_MOUSE
NC score	0.748166 (rank : 37)	θ value	2.69671e-12 (rank : 38)
Query Neighborhood Hits	253	Target Neighborhood Hits	102	Shared Neighborhood Hits	88
SwissProt Accessions	Q920N7	Gene names	Syt12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

SYT12_HUMAN
NC score	0.744024 (rank : 38)	θ value	1.47974e-10 (rank : 41)
Query Neighborhood Hits	253	Target Neighborhood Hits	100	Shared Neighborhood Hits	86
SwissProt Accessions	Q8IV01	Gene names	SYT12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

SYT15_HUMAN
NC score	0.739293 (rank : 39)	θ value	8.67504e-11 (rank : 39)
Query Neighborhood Hits	253	Target Neighborhood Hits	112	Shared Neighborhood Hits	91
SwissProt Accessions	Q9BQS2, Q7Z439, Q7Z440	Gene names	SYT15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV) (Chr10Syt).

SYT8_MOUSE
NC score	0.729915 (rank : 40)	θ value	1.69304e-06 (rank : 61)
Query Neighborhood Hits	253	Target Neighborhood Hits	94	Shared Neighborhood Hits	84
SwissProt Accessions	Q9R0N6, Q64366, Q8C6E7	Gene names	Syt8
Domain Architecture
Description	Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII).

SYT15_MOUSE
NC score	0.700857 (rank : 41)	θ value	5.26297e-08 (rank : 54)
Query Neighborhood Hits	253	Target Neighborhood Hits	100	Shared Neighborhood Hits	85
SwissProt Accessions	Q8C6N3, Q7TN81, Q7TN82, Q8C999	Gene names	Syt15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV).

FA62A_HUMAN
NC score	0.630748 (rank : 42)	θ value	8.11959e-09 (rank : 52)
Query Neighborhood Hits	253	Target Neighborhood Hits	168	Shared Neighborhood Hits	102
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

FA62A_MOUSE
NC score	0.629473 (rank : 43)	θ value	1.80886e-08 (rank : 53)
Query Neighborhood Hits	253	Target Neighborhood Hits	155	Shared Neighborhood Hits	102
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

SYT13_HUMAN
NC score	0.601217 (rank : 44)	θ value	0.0193708 (rank : 91)
Query Neighborhood Hits	253	Target Neighborhood Hits	76	Shared Neighborhood Hits	66
SwissProt Accessions	Q7L8C5, Q9BQS3, Q9H041, Q9P2C0	Gene names	SYT13, KIAA1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

SYT13_MOUSE
NC score	0.593591 (rank : 45)	θ value	0.0193708 (rank : 92)
Query Neighborhood Hits	253	Target Neighborhood Hits	69	Shared Neighborhood Hits	66
SwissProt Accessions	Q9EQT6, Q6ZPR2, Q8BRK6	Gene names	Syt13, Kiaa1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

SYT14_MOUSE
NC score	0.580211 (rank : 46)	θ value	0.00390308 (rank : 81)
Query Neighborhood Hits	253	Target Neighborhood Hits	82	Shared Neighborhood Hits	66
SwissProt Accessions	Q7TN84	Gene names	Syt14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

SYT14_HUMAN
NC score	0.577492 (rank : 47)	θ value	0.00509761 (rank : 83)
Query Neighborhood Hits	253	Target Neighborhood Hits	81	Shared Neighborhood Hits	60
SwissProt Accessions	Q8NB59, Q5THX7, Q707N3, Q707N4, Q707N5, Q707N6, Q707N7	Gene names	SYT14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

RIMS1_HUMAN
NC score	0.561191 (rank : 48)	θ value	1.9326e-10 (rank : 42)
Query Neighborhood Hits	253	Target Neighborhood Hits	437	Shared Neighborhood Hits	109
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

RASL2_HUMAN
NC score	0.560837 (rank : 49)	θ value	2.44474e-05 (rank : 68)
Query Neighborhood Hits	253	Target Neighborhood Hits	161	Shared Neighborhood Hits	98
SwissProt Accessions	O43374, O60286, Q86UW3, Q96QU0	Gene names	RASA4, CAPRI, GAPL, KIAA0538
Domain Architecture
Description	Ras GTPase-activating protein 4 (RasGAP-activating-like protein 2) (Calcium-promoted Ras inactivator).

RIMS2_HUMAN
NC score	0.546741 (rank : 50)	θ value	4.45536e-07 (rank : 56)
Query Neighborhood Hits	253	Target Neighborhood Hits	342	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
NC score	0.540532 (rank : 51)	θ value	4.45536e-07 (rank : 57)
Query Neighborhood Hits	253	Target Neighborhood Hits	376	Shared Neighborhood Hits	111
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

PCLO_HUMAN
NC score	0.516327 (rank : 52)	θ value	1.058e-16 (rank : 28)
Query Neighborhood Hits	253	Target Neighborhood Hits	2046	Shared Neighborhood Hits	171
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

RIMS4_MOUSE
NC score	0.494515 (rank : 53)	θ value	2.88788e-06 (rank : 64)
Query Neighborhood Hits	253	Target Neighborhood Hits	76	Shared Neighborhood Hits	70
SwissProt Accessions	P60191	Gene names	Rims4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

RIMS4_HUMAN
NC score	0.491002 (rank : 54)	θ value	3.77169e-06 (rank : 65)
Query Neighborhood Hits	253	Target Neighborhood Hits	76	Shared Neighborhood Hits	70
SwissProt Accessions	Q9H426, Q5JWT7	Gene names	RIMS4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

PCLO_MOUSE
NC score	0.486079 (rank : 55)	θ value	2.60593e-15 (rank : 33)
Query Neighborhood Hits	253	Target Neighborhood Hits	2275	Shared Neighborhood Hits	178
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

P3C2B_HUMAN
NC score	0.479542 (rank : 56)	θ value	9.92553e-07 (rank : 58)
Query Neighborhood Hits	253	Target Neighborhood Hits	148	Shared Neighborhood Hits	81
SwissProt Accessions	O00750, O95666, Q5SW99	Gene names	PIK3C2B
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-beta) (PtdIns-3-kinase C2 beta) (PI3K-C2beta) (C2-PI3K).

RASL1_HUMAN
NC score	0.458779 (rank : 57)	θ value	0.0252991 (rank : 93)
Query Neighborhood Hits	253	Target Neighborhood Hits	142	Shared Neighborhood Hits	88
SwissProt Accessions	O95294, Q52M03, Q96CC7	Gene names	RASAL1, RASAL
Domain Architecture
Description	RasGAP-activating-like protein 1.

P3C2A_HUMAN
NC score	0.453910 (rank : 58)	θ value	2.52405e-10 (rank : 44)
Query Neighborhood Hits	253	Target Neighborhood Hits	188	Shared Neighborhood Hits	76
SwissProt Accessions	O00443	Gene names	PIK3C2A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha).

P3C2A_MOUSE
NC score	0.450524 (rank : 59)	θ value	1.63604e-09 (rank : 48)
Query Neighborhood Hits	253	Target Neighborhood Hits	181	Shared Neighborhood Hits	79
SwissProt Accessions	Q61194, Q61182	Gene names	Pik3c2a, Cpk
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).

RASL1_MOUSE
NC score	0.448602 (rank : 60)	θ value	0.00665767 (rank : 84)
Query Neighborhood Hits	253	Target Neighborhood Hits	148	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Z268	Gene names	Rasal1, Rasal
Domain Architecture
Description	RasGAP-activating-like protein 1.

RASA2_MOUSE
NC score	0.444373 (rank : 61)	θ value	4.45536e-07 (rank : 55)
Query Neighborhood Hits	253	Target Neighborhood Hits	159	Shared Neighborhood Hits	82
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

RASA2_HUMAN
NC score	0.438482 (rank : 62)	θ value	1.29631e-06 (rank : 59)
Query Neighborhood Hits	253	Target Neighborhood Hits	157	Shared Neighborhood Hits	82
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

UN13D_HUMAN
NC score	0.438466 (rank : 63)	θ value	3.0926 (rank : 188)
Query Neighborhood Hits	253	Target Neighborhood Hits	117	Shared Neighborhood Hits	90
SwissProt Accessions	Q70J99, Q9H7K5	Gene names	UNC13D
Domain Architecture	No domain graphic available
Description	Unc-13 homolog D (Munc13-4).

K0528_HUMAN
NC score	0.421305 (rank : 64)	θ value	0.00390308 (rank : 79)
Query Neighborhood Hits	253	Target Neighborhood Hits	96	Shared Neighborhood Hits	79
SwissProt Accessions	Q86YS7, O60280, Q7Z619, Q86SU3	Gene names	KIAA0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

K0528_MOUSE
NC score	0.420608 (rank : 65)	θ value	0.00390308 (rank : 80)
Query Neighborhood Hits	253	Target Neighborhood Hits	102	Shared Neighborhood Hits	78
SwissProt Accessions	Q7TPS5, Q3TQY6, Q6A052, Q80VA1, Q8C0U3, Q8CID5, Q9CS85	Gene names	Kiaa0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

RASA3_HUMAN
NC score	0.418576 (rank : 66)	θ value	1.25267e-09 (rank : 47)
Query Neighborhood Hits	253	Target Neighborhood Hits	166	Shared Neighborhood Hits	82
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

BAIP3_HUMAN
NC score	0.404498 (rank : 67)	θ value	8.99809 (rank : 234)
Query Neighborhood Hits	253	Target Neighborhood Hits	108	Shared Neighborhood Hits	83
SwissProt Accessions	O94812, O94839, Q2M226, Q658J2, Q76N05, Q96RZ3, Q9UJK1	Gene names	BAIAP3, KIAA0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

BAIP3_MOUSE
NC score	0.403186 (rank : 68)	θ value	6.88961 (rank : 218)
Query Neighborhood Hits	253	Target Neighborhood Hits	112	Shared Neighborhood Hits	88
SwissProt Accessions	Q80TT2, Q6RUT4	Gene names	Baiap3, Gm937, Kiaa0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

RIMS3_HUMAN
NC score	0.386532 (rank : 69)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	253	Target Neighborhood Hits	66	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UJD0, Q92511	Gene names	RIMS3, KIAA0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

RIMS3_MOUSE
NC score	0.384361 (rank : 70)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	253	Target Neighborhood Hits	67	Shared Neighborhood Hits	64
SwissProt Accessions	Q80U57	Gene names	Rims3, Kiaa0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

RFIP2_HUMAN
NC score	0.374588 (rank : 71)	θ value	2.21117e-06 (rank : 63)
Query Neighborhood Hits	253	Target Neighborhood Hits	97	Shared Neighborhood Hits	76
SwissProt Accessions	Q7L804, Q9Y2F0	Gene names	RAB11FIP2, KIAA0941
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 2 (Rab11-FIP2) (NRip11).

DYSF_HUMAN
NC score	0.364455 (rank : 72)	θ value	0.000158464 (rank : 70)
Query Neighborhood Hits	253	Target Neighborhood Hits	170	Shared Neighborhood Hits	101
SwissProt Accessions	O75923, O75696, Q9UEN7	Gene names	DYSF, FER1L1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

RASA3_MOUSE
NC score	0.362483 (rank : 73)	θ value	2.21117e-06 (rank : 62)
Query Neighborhood Hits	253	Target Neighborhood Hits	144	Shared Neighborhood Hits	75
SwissProt Accessions	Q60790	Gene names	Rasa3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) (GapIII).

DYSF_MOUSE
NC score	0.358971 (rank : 74)	θ value	0.00509761 (rank : 82)
Query Neighborhood Hits	253	Target Neighborhood Hits	162	Shared Neighborhood Hits	104
SwissProt Accessions	Q9ESD7, Q9QXC0	Gene names	Dysf, Fer1l1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

MYOF_HUMAN
NC score	0.353639 (rank : 75)	θ value	0.0113563 (rank : 87)
Query Neighborhood Hits	253	Target Neighborhood Hits	147	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NZM1, Q9HBU3, Q9NZM0, Q9ULL3, Q9Y4U4	Gene names	FER1L3, KIAA1207, MYOF
Domain Architecture
Description	Myoferlin (Fer-1-like protein 3).

NED4L_HUMAN
NC score	0.310837 (rank : 76)	θ value	1.87187e-05 (rank : 66)
Query Neighborhood Hits	253	Target Neighborhood Hits	238	Shared Neighborhood Hits	102
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

OTOF_HUMAN
NC score	0.308057 (rank : 77)	θ value	0.00228821 (rank : 75)
Query Neighborhood Hits	253	Target Neighborhood Hits	168	Shared Neighborhood Hits	83
SwissProt Accessions	Q9HC10, Q9HC08, Q9HC09, Q9Y650	Gene names	OTOF, FER1L2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

NED4L_MOUSE
NC score	0.306873 (rank : 78)	θ value	1.87187e-05 (rank : 67)
Query Neighborhood Hits	253	Target Neighborhood Hits	231	Shared Neighborhood Hits	100
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

OTOF_MOUSE
NC score	0.304718 (rank : 79)	θ value	0.00298849 (rank : 77)
Query Neighborhood Hits	253	Target Neighborhood Hits	196	Shared Neighborhood Hits	87
SwissProt Accessions	Q9ESF1, Q9ESF2	Gene names	Otof, Fer1l2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

UN13A_HUMAN
NC score	0.299770 (rank : 80)	θ value	0.00665767 (rank : 85)
Query Neighborhood Hits	253	Target Neighborhood Hits	285	Shared Neighborhood Hits	100
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

UN13B_MOUSE
NC score	0.296358 (rank : 81)	θ value	0.0252991 (rank : 95)
Query Neighborhood Hits	253	Target Neighborhood Hits	210	Shared Neighborhood Hits	89
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

UN13B_HUMAN
NC score	0.291974 (rank : 82)	θ value	0.0431538 (rank : 101)
Query Neighborhood Hits	253	Target Neighborhood Hits	217	Shared Neighborhood Hits	94
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

PA24D_MOUSE
NC score	0.291667 (rank : 83)	θ value	0.0431538 (rank : 98)
Query Neighborhood Hits	253	Target Neighborhood Hits	100	Shared Neighborhood Hits	80
SwissProt Accessions	Q50L43, Q3TJC5	Gene names	Pla2g4d
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

NEDD4_HUMAN
NC score	0.289823 (rank : 84)	θ value	4.1701e-05 (rank : 69)
Query Neighborhood Hits	253	Target Neighborhood Hits	214	Shared Neighborhood Hits	100
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

TAC2N_HUMAN
NC score	0.281605 (rank : 85)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	253	Target Neighborhood Hits	47	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N9U0	Gene names	MTAC2D1, C14orf47
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

TAC2N_MOUSE
NC score	0.280643 (rank : 86)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	253	Target Neighborhood Hits	43	Shared Neighborhood Hits	36
SwissProt Accessions	Q91XT6, Q9D4A0	Gene names	Mtac2d1
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

NEDD4_MOUSE
NC score	0.276585 (rank : 87)	θ value	0.00020696 (rank : 71)
Query Neighborhood Hits	253	Target Neighborhood Hits	212	Shared Neighborhood Hits	99
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

MYRIP_MOUSE
NC score	0.266442 (rank : 88)	θ value	0.0148317 (rank : 89)
Query Neighborhood Hits	253	Target Neighborhood Hits	207	Shared Neighborhood Hits	38
SwissProt Accessions	Q8K3I4, Q8CFC0, Q8K4H5	Gene names	Myrip, Slac2c
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

MELPH_HUMAN
NC score	0.263873 (rank : 89)	θ value	0.00035302 (rank : 72)
Query Neighborhood Hits	253	Target Neighborhood Hits	145	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BV36, Q9HA71	Gene names	MLPH, SLAC2A
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Synaptotagmin-like protein 2a) (Slp homolog lacking C2 domains a).

MYRIP_HUMAN
NC score	0.262742 (rank : 90)	θ value	0.00175202 (rank : 73)
Query Neighborhood Hits	253	Target Neighborhood Hits	269	Shared Neighborhood Hits	37
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

MELPH_MOUSE
NC score	0.257012 (rank : 91)	θ value	0.00298849 (rank : 76)
Query Neighborhood Hits	253	Target Neighborhood Hits	112	Shared Neighborhood Hits	20
SwissProt Accessions	Q91V27, Q99N53	Gene names	Mlph, Ln, Slac2a
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Leaden protein) (Synaptotagmin-like protein 2a) (Slac2-a) (Slp homolog lacking C2 domains a).

PA24D_HUMAN
NC score	0.254718 (rank : 92)	θ value	0.0148317 (rank : 90)
Query Neighborhood Hits	253	Target Neighborhood Hits	97	Shared Neighborhood Hits	77
SwissProt Accessions	Q86XP0, Q8N176	Gene names	PLA2G4D
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

RGS3_HUMAN
NC score	0.214848 (rank : 93)	θ value	0.0252991 (rank : 94)
Query Neighborhood Hits	253	Target Neighborhood Hits	1375	Shared Neighborhood Hits	121
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SLC2B_HUMAN
NC score	0.209221 (rank : 94)	θ value	1.29631e-06 (rank : 60)
Query Neighborhood Hits	253	Target Neighborhood Hits	214	Shared Neighborhood Hits	31
SwissProt Accessions	Q8NEV8, Q9Y4D6	Gene names	EXPH5, KIAA0624, SLAC2B
Domain Architecture	No domain graphic available
Description	Slp homolog lacking C2 domains b (Exophilin-5).

KPCG_HUMAN
NC score	0.206000 (rank : 95)	θ value	2.52405e-10 (rank : 43)
Query Neighborhood Hits	253	Target Neighborhood Hits	1126	Shared Neighborhood Hits	109
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

KPCG_MOUSE
NC score	0.205697 (rank : 96)	θ value	3.29651e-10 (rank : 45)
Query Neighborhood Hits	253	Target Neighborhood Hits	1123	Shared Neighborhood Hits	108
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

PA24B_MOUSE
NC score	0.201381 (rank : 97)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	253	Target Neighborhood Hits	102	Shared Neighborhood Hits	69
SwissProt Accessions	Q4QQM1, Q80VV8, Q91W88	Gene names	Pla2g4b
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

P3C2G_MOUSE
NC score	0.196283 (rank : 98)	θ value	0.00175202 (rank : 74)
Query Neighborhood Hits	253	Target Neighborhood Hits	113	Shared Neighborhood Hits	61
SwissProt Accessions	O70167, O70168	Gene names	Pik3c2g
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).

KPCA_HUMAN
NC score	0.191864 (rank : 99)	θ value	5.62301e-10 (rank : 46)
Query Neighborhood Hits	253	Target Neighborhood Hits	1070	Shared Neighborhood Hits	110
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KPCB_MOUSE
NC score	0.190778 (rank : 100)	θ value	4.76016e-09 (rank : 51)
Query Neighborhood Hits	253	Target Neighborhood Hits	1117	Shared Neighborhood Hits	108
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCA_MOUSE
NC score	0.188747 (rank : 101)	θ value	2.13673e-09 (rank : 49)
Query Neighborhood Hits	253	Target Neighborhood Hits	1067	Shared Neighborhood Hits	110
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KPCB_HUMAN
NC score	0.188607 (rank : 102)	θ value	3.64472e-09 (rank : 50)
Query Neighborhood Hits	253	Target Neighborhood Hits	1121	Shared Neighborhood Hits	109
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

RFIP1_MOUSE
NC score	0.188002 (rank : 103)	θ value	0.0330416 (rank : 96)
Query Neighborhood Hits	253	Target Neighborhood Hits	152	Shared Neighborhood Hits	49
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

PA24E_MOUSE
NC score	0.186690 (rank : 104)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	253	Target Neighborhood Hits	95	Shared Neighborhood Hits	74
SwissProt Accessions	Q50L42, Q8BX44	Gene names	Pla2g4e
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

RFIP1_HUMAN
NC score	0.183811 (rank : 105)	θ value	0.0563607 (rank : 102)
Query Neighborhood Hits	253	Target Neighborhood Hits	236	Shared Neighborhood Hits	58
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

P3C2G_HUMAN
NC score	0.177692 (rank : 106)	θ value	0.00298849 (rank : 78)
Query Neighborhood Hits	253	Target Neighborhood Hits	92	Shared Neighborhood Hits	45
SwissProt Accessions	O75747	Gene names	PIK3C2G
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).

CPNE3_HUMAN
NC score	0.172657 (rank : 107)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	253	Target Neighborhood Hits	90	Shared Neighborhood Hits	64
SwissProt Accessions	O75131, Q8IYA1	Gene names	CPNE3, CPN3, KIAA0636
Domain Architecture
Description	Copine-3 (Copine III).

CPNE3_MOUSE
NC score	0.172602 (rank : 108)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	253	Target Neighborhood Hits	90	Shared Neighborhood Hits	66
SwissProt Accessions	Q8BT60, Q5CZX9, Q5DU22	Gene names	Cpne3, Kiaa0636
Domain Architecture
Description	Copine-3 (Copine III).

PA24A_MOUSE
NC score	0.170626 (rank : 109)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	253	Target Neighborhood Hits	100	Shared Neighborhood Hits	71
SwissProt Accessions	P47713	Gene names	Pla2g4a, Cpla2, Pla2g4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

PA24E_HUMAN
NC score	0.168366 (rank : 110)	θ value	8.99809 (rank : 246)
Query Neighborhood Hits	253	Target Neighborhood Hits	89	Shared Neighborhood Hits	69
SwissProt Accessions	Q3MJ16, Q6ZSC0	Gene names	PLA2G4E
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

CPNE5_HUMAN
NC score	0.166124 (rank : 111)	θ value	0.813845 (rank : 139)
Query Neighborhood Hits	253	Target Neighborhood Hits	88	Shared Neighborhood Hits	64
SwissProt Accessions	Q9HCH3	Gene names	CPNE5, KIAA1599
Domain Architecture
Description	Copine-5 (Copine V).

CPNE5_MOUSE
NC score	0.164737 (rank : 112)	θ value	4.03905 (rank : 191)
Query Neighborhood Hits	253	Target Neighborhood Hits	86	Shared Neighborhood Hits	64
SwissProt Accessions	Q8JZW4	Gene names	Cpne5
Domain Architecture
Description	Copine-5 (Copine V).

CPNE8_HUMAN
NC score	0.160269 (rank : 113)	θ value	1.81305 (rank : 164)
Query Neighborhood Hits	253	Target Neighborhood Hits	86	Shared Neighborhood Hits	64
SwissProt Accessions	Q86YQ8, Q2TB41	Gene names	CPNE8
Domain Architecture
Description	Copine-8 (Copine VIII).

PA24B_HUMAN
NC score	0.160105 (rank : 114)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	253	Target Neighborhood Hits	89	Shared Neighborhood Hits	63
SwissProt Accessions	O95712, Q59GF9, Q8TB10, Q9UKV7	Gene names	PLA2G4B
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

PA24A_HUMAN
NC score	0.158103 (rank : 115)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	253	Target Neighborhood Hits	88	Shared Neighborhood Hits	70
SwissProt Accessions	P47712	Gene names	PLA2G4A, CPLA2, PLA2G4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

CPNE8_MOUSE
NC score	0.156768 (rank : 116)	θ value	1.81305 (rank : 165)
Query Neighborhood Hits	253	Target Neighborhood Hits	85	Shared Neighborhood Hits	64
SwissProt Accessions	Q9DC53, Q9CUZ8	Gene names	Cpne8
Domain Architecture
Description	Copine-8 (Copine VIII).

CPNE7_HUMAN
NC score	0.155875 (rank : 117)	θ value	0.47712 (rank : 128)
Query Neighborhood Hits	253	Target Neighborhood Hits	92	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UBL6	Gene names	CPNE7
Domain Architecture
Description	Copine-7 (Copine VII).

CPNE2_MOUSE
NC score	0.150236 (rank : 118)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	253	Target Neighborhood Hits	82	Shared Neighborhood Hits	59
SwissProt Accessions	P59108, Q8K1D7	Gene names	Cpne2
Domain Architecture
Description	Copine-2 (Copine II).

ITSN2_HUMAN
NC score	0.150064 (rank : 119)	θ value	0.62314 (rank : 135)
Query Neighborhood Hits	253	Target Neighborhood Hits	1173	Shared Neighborhood Hits	97
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

CPNE1_MOUSE
NC score	0.149843 (rank : 120)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	253	Target Neighborhood Hits	83	Shared Neighborhood Hits	61
SwissProt Accessions	Q8C166, Q925K4, Q925K5	Gene names	Cpne1
Domain Architecture
Description	Copine-1 (Copine I).

CPNE2_HUMAN
NC score	0.148638 (rank : 121)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	253	Target Neighborhood Hits	75	Shared Neighborhood Hits	56
SwissProt Accessions	Q96FN4, Q68D19, Q86XP9	Gene names	CPNE2
Domain Architecture
Description	Copine-2 (Copine II).

ITSN2_MOUSE
NC score	0.133630 (rank : 122)	θ value	5.27518 (rank : 203)
Query Neighborhood Hits	253	Target Neighborhood Hits	1371	Shared Neighborhood Hits	98
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

CPNE1_HUMAN
NC score	0.126829 (rank : 123)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	253	Target Neighborhood Hits	70	Shared Neighborhood Hits	56
SwissProt Accessions	Q99829, Q6IBL3, Q9H243, Q9NTZ7	Gene names	CPNE1, CPN1
Domain Architecture
Description	Copine-1 (Copine I).

PA24F_MOUSE
NC score	0.125306 (rank : 124)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	253	Target Neighborhood Hits	93	Shared Neighborhood Hits	59
SwissProt Accessions	Q50L41, Q80VQ8, Q80VV9	Gene names	Pla2g4f
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

CPNE6_HUMAN
NC score	0.112954 (rank : 125)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	253	Target Neighborhood Hits	85	Shared Neighborhood Hits	58
SwissProt Accessions	O95741, Q53HA6, Q8WVG1	Gene names	CPNE6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

PLCD1_HUMAN
NC score	0.112644 (rank : 126)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	253	Target Neighborhood Hits	93	Shared Neighborhood Hits	50
SwissProt Accessions	P51178	Gene names	PLCD1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

CPNE6_MOUSE
NC score	0.111664 (rank : 127)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	253	Target Neighborhood Hits	87	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Z140	Gene names	Cpne6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

WWC1_MOUSE
NC score	0.107529 (rank : 128)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	253	Target Neighborhood Hits	290	Shared Neighborhood Hits	37
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

ITSN1_MOUSE
NC score	0.107415 (rank : 129)	θ value	1.81305 (rank : 167)
Query Neighborhood Hits	253	Target Neighborhood Hits	1669	Shared Neighborhood Hits	116
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

SMUF1_HUMAN
NC score	0.106886 (rank : 130)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	253	Target Neighborhood Hits	135	Shared Neighborhood Hits	57
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

PA24F_HUMAN
NC score	0.106141 (rank : 131)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	253	Target Neighborhood Hits	78	Shared Neighborhood Hits	57
SwissProt Accessions	Q68DD2, Q6ZMC8	Gene names	PLA2G4F
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

SMUF1_MOUSE
NC score	0.105729 (rank : 132)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	253	Target Neighborhood Hits	142	Shared Neighborhood Hits	57
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

SMUF2_HUMAN
NC score	0.105667 (rank : 133)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	253	Target Neighborhood Hits	142	Shared Neighborhood Hits	59
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

ITSN1_HUMAN
NC score	0.104893 (rank : 134)	θ value	1.81305 (rank : 166)
Query Neighborhood Hits	253	Target Neighborhood Hits	1757	Shared Neighborhood Hits	110
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

CPNE4_HUMAN
NC score	0.100952 (rank : 135)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	253	Target Neighborhood Hits	70	Shared Neighborhood Hits	52
SwissProt Accessions	Q96A23, Q8TEX1	Gene names	CPNE4
Domain Architecture
Description	Copine-4 (Copine IV) (Copine-8).

CPNE4_MOUSE
NC score	0.097461 (rank : 136)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	253	Target Neighborhood Hits	67	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BLR2	Gene names	Cpne4
Domain Architecture	No domain graphic available
Description	Copine-4 (Copine IV).

WWC1_HUMAN
NC score	0.078746 (rank : 137)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	253	Target Neighborhood Hits	290	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

SYT8_HUMAN
NC score	0.076621 (rank : 138)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	253	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NBV8, Q9NSV9	Gene names	SYT8
Domain Architecture	No domain graphic available
Description	Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII).

PLCD1_MOUSE
NC score	0.075581 (rank : 139)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	253	Target Neighborhood Hits	106	Shared Neighborhood Hits	49
SwissProt Accessions	Q8R3B1	Gene names	Plcd1, Plcd
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

PDZD8_HUMAN
NC score	0.069042 (rank : 140)	θ value	0.279714 (rank : 121)
Query Neighborhood Hits	253	Target Neighborhood Hits	185	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

MARCS_HUMAN
NC score	0.069038 (rank : 141)	θ value	0.0961366 (rank : 107)
Query Neighborhood Hits	253	Target Neighborhood Hits	204	Shared Neighborhood Hits	20
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

IWS1_HUMAN
NC score	0.068512 (rank : 142)	θ value	1.81305 (rank : 168)
Query Neighborhood Hits	253	Target Neighborhood Hits	1241	Shared Neighborhood Hits	89
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

RASA1_HUMAN
NC score	0.066748 (rank : 143)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	253	Target Neighborhood Hits	258	Shared Neighborhood Hits	25
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

NOLC1_HUMAN
NC score	0.064512 (rank : 144)	θ value	1.38821 (rank : 156)
Query Neighborhood Hits	253	Target Neighborhood Hits	452	Shared Neighborhood Hits	46
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

BASP_HUMAN
NC score	0.064167 (rank : 145)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	253	Target Neighborhood Hits	321	Shared Neighborhood Hits	28
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

AKA12_HUMAN
NC score	0.063982 (rank : 146)	θ value	0.0961366 (rank : 105)
Query Neighborhood Hits	253	Target Neighborhood Hits	825	Shared Neighborhood Hits	74
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

BSN_HUMAN
NC score	0.061637 (rank : 147)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	253	Target Neighborhood Hits	1537	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

TXND2_HUMAN
NC score	0.059942 (rank : 148)	θ value	0.0563607 (rank : 104)
Query Neighborhood Hits	253	Target Neighborhood Hits	793	Shared Neighborhood Hits	65
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

BSN_MOUSE
NC score	0.059937 (rank : 149)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	253	Target Neighborhood Hits	2057	Shared Neighborhood Hits	65
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

DAB2P_HUMAN
NC score	0.059438 (rank : 150)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	253	Target Neighborhood Hits	303	Shared Neighborhood Hits	18
SwissProt Accessions	Q5VWQ8, Q8TDL2, Q96SE1, Q9C0C0	Gene names	DAB2IP, AF9Q34, AIP1, KIAA1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein) (DAB2 interaction protein) (ASK-interacting protein 1).

SRRM2_MOUSE
NC score	0.059368 (rank : 151)	θ value	2.36792 (rank : 182)
Query Neighborhood Hits	253	Target Neighborhood Hits	1470	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

RBBP6_MOUSE
NC score	0.058099 (rank : 152)	θ value	0.813845 (rank : 144)
Query Neighborhood Hits	253	Target Neighborhood Hits	1014	Shared Neighborhood Hits	64
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RBBP6_HUMAN
NC score	0.057650 (rank : 153)	θ value	0.0431538 (rank : 99)
Query Neighborhood Hits	253	Target Neighborhood Hits	1135	Shared Neighborhood Hits	74
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

IWS1_MOUSE
NC score	0.057285 (rank : 154)	θ value	1.81305 (rank : 169)
Query Neighborhood Hits	253	Target Neighborhood Hits	1258	Shared Neighborhood Hits	89
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

DSPP_MOUSE
NC score	0.057109 (rank : 155)	θ value	0.163984 (rank : 114)
Query Neighborhood Hits	253	Target Neighborhood Hits	491	Shared Neighborhood Hits	47
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

DAB2P_MOUSE
NC score	0.057065 (rank : 156)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	253	Target Neighborhood Hits	284	Shared Neighborhood Hits	16
SwissProt Accessions	Q3UHC7, Q3TPD5, Q3UH44, Q6JTV1, Q80T97	Gene names	Dab2ip, Kiaa1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein).

PK3CG_HUMAN
NC score	0.056864 (rank : 157)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	253	Target Neighborhood Hits	41	Shared Neighborhood Hits	5
SwissProt Accessions	P48736, Q8IV23, Q9BZC8	Gene names	PIK3CG
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

PK3CG_MOUSE
NC score	0.056707 (rank : 158)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	253	Target Neighborhood Hits	43	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JHG7	Gene names	Pik3cg, Pi3kg1
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

ENL_HUMAN
NC score	0.056644 (rank : 159)	θ value	0.813845 (rank : 140)
Query Neighborhood Hits	253	Target Neighborhood Hits	305	Shared Neighborhood Hits	34
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

DSPP_HUMAN
NC score	0.056391 (rank : 160)	θ value	2.36792 (rank : 175)
Query Neighborhood Hits	253	Target Neighborhood Hits	645	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

PK3CA_HUMAN
NC score	0.055376 (rank : 161)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	253	Target Neighborhood Hits	45	Shared Neighborhood Hits	7
SwissProt Accessions	P42336, Q99762	Gene names	PIK3CA
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).

PK3CA_MOUSE
NC score	0.055302 (rank : 162)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	253	Target Neighborhood Hits	48	Shared Neighborhood Hits	5
SwissProt Accessions	P42337	Gene names	Pik3ca
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).

WWP1_HUMAN
NC score	0.053967 (rank : 163)	θ value	5.27518 (rank : 214)
Query Neighborhood Hits	253	Target Neighborhood Hits	262	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

TGON2_HUMAN
NC score	0.053097 (rank : 164)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	253	Target Neighborhood Hits	1037	Shared Neighborhood Hits	74
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

LEO1_HUMAN
NC score	0.053040 (rank : 165)	θ value	0.0113563 (rank : 86)
Query Neighborhood Hits	253	Target Neighborhood Hits	958	Shared Neighborhood Hits	61
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

PK3CD_HUMAN
NC score	0.052784 (rank : 166)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	253	Target Neighborhood Hits	40	Shared Neighborhood Hits	5
SwissProt Accessions	O00329, O15445	Gene names	PIK3CD
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit delta) (PtdIns-3- kinase p110) (PI3K) (p110delta).

PK3CD_MOUSE
NC score	0.052720 (rank : 167)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	253	Target Neighborhood Hits	42	Shared Neighborhood Hits	5
SwissProt Accessions	O35904	Gene names	Pik3cd
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit delta) (PtdIns-3- kinase p110) (PI3K) (p110delta).

PK3CB_MOUSE
NC score	0.052276 (rank : 168)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	253	Target Neighborhood Hits	49	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BTI9	Gene names	Pik3cb
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).

PK3CB_HUMAN
NC score	0.052253 (rank : 169)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	253	Target Neighborhood Hits	43	Shared Neighborhood Hits	5
SwissProt Accessions	P42338	Gene names	PIK3CB
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).

TXND2_MOUSE
NC score	0.050916 (rank : 170)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	253	Target Neighborhood Hits	828	Shared Neighborhood Hits	69
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

WWP1_MOUSE
NC score	0.050050 (rank : 171)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	253	Target Neighborhood Hits	138	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

PININ_HUMAN
NC score	0.049671 (rank : 172)	θ value	0.0961366 (rank : 110)
Query Neighborhood Hits	253	Target Neighborhood Hits	753	Shared Neighborhood Hits	51
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

MINT_HUMAN
NC score	0.049491 (rank : 173)	θ value	0.0961366 (rank : 109)
Query Neighborhood Hits	253	Target Neighborhood Hits	1291	Shared Neighborhood Hits	75
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

XRCC4_HUMAN
NC score	0.046534 (rank : 174)	θ value	0.0113563 (rank : 88)
Query Neighborhood Hits	253	Target Neighborhood Hits	131	Shared Neighborhood Hits	8
SwissProt Accessions	Q13426, Q9BS72, Q9UP94	Gene names	XRCC4
Domain Architecture
Description	DNA-repair protein XRCC4 (X-ray repair cross-complementing protein 4).

TRIPC_HUMAN
NC score	0.045529 (rank : 175)	θ value	0.62314 (rank : 137)
Query Neighborhood Hits	253	Target Neighborhood Hits	319	Shared Neighborhood Hits	29
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

ASXL1_MOUSE
NC score	0.045184 (rank : 176)	θ value	0.125558 (rank : 111)
Query Neighborhood Hits	253	Target Neighborhood Hits	182	Shared Neighborhood Hits	21
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

MINT_MOUSE
NC score	0.044933 (rank : 177)	θ value	1.81305 (rank : 170)
Query Neighborhood Hits	253	Target Neighborhood Hits	1514	Shared Neighborhood Hits	74
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

ATRX_MOUSE
NC score	0.044876 (rank : 178)	θ value	0.0961366 (rank : 106)
Query Neighborhood Hits	253	Target Neighborhood Hits	682	Shared Neighborhood Hits	49
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

ERIC1_HUMAN
NC score	0.044223 (rank : 179)	θ value	0.47712 (rank : 129)
Query Neighborhood Hits	253	Target Neighborhood Hits	364	Shared Neighborhood Hits	35
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

TCAL5_MOUSE
NC score	0.043062 (rank : 180)	θ value	0.0563607 (rank : 103)
Query Neighborhood Hits	253	Target Neighborhood Hits	63	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CCT4, Q497R6	Gene names	Tceal5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

MCPH1_MOUSE
NC score	0.042839 (rank : 181)	θ value	0.0961366 (rank : 108)
Query Neighborhood Hits	253	Target Neighborhood Hits	116	Shared Neighborhood Hits	8
SwissProt Accessions	Q7TT79, Q8BNI9, Q8C9I7	Gene names	Mcph1
Domain Architecture
Description	Microcephalin.

MDN1_HUMAN
NC score	0.042626 (rank : 182)	θ value	5.27518 (rank : 207)
Query Neighborhood Hits	253	Target Neighborhood Hits	662	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

RSF1_HUMAN
NC score	0.042422 (rank : 183)	θ value	0.21417 (rank : 118)
Query Neighborhood Hits	253	Target Neighborhood Hits	539	Shared Neighborhood Hits	47
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

TCAL3_MOUSE
NC score	0.039757 (rank : 184)	θ value	2.36792 (rank : 183)
Query Neighborhood Hits	253	Target Neighborhood Hits	132	Shared Neighborhood Hits	22
SwissProt Accessions	Q8R0A5, Q9CYK5, Q9D1S4	Gene names	Tceal3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

PININ_MOUSE
NC score	0.039573 (rank : 185)	θ value	1.06291 (rank : 152)
Query Neighborhood Hits	253	Target Neighborhood Hits	777	Shared Neighborhood Hits	49
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

OXR1_MOUSE
NC score	0.039462 (rank : 186)	θ value	1.06291 (rank : 151)
Query Neighborhood Hits	253	Target Neighborhood Hits	516	Shared Neighborhood Hits	53
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

MAP1B_HUMAN
NC score	0.037794 (rank : 187)	θ value	4.03905 (rank : 194)
Query Neighborhood Hits	253	Target Neighborhood Hits	903	Shared Neighborhood Hits	72
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

ATRX_HUMAN
NC score	0.037372 (rank : 188)	θ value	0.21417 (rank : 117)
Query Neighborhood Hits	253	Target Neighborhood Hits	842	Shared Neighborhood Hits	61
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

WWC3_HUMAN
NC score	0.036995 (rank : 189)	θ value	0.0330416 (rank : 97)
Query Neighborhood Hits	253	Target Neighborhood Hits	193	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ULE0, Q659C1, Q9BTQ1	Gene names	WWC3, KIAA1280
Domain Architecture	No domain graphic available
Description	WWC family member 3.

NFH_MOUSE
NC score	0.035748 (rank : 190)	θ value	0.125558 (rank : 113)
Query Neighborhood Hits	253	Target Neighborhood Hits	2247	Shared Neighborhood Hits	97
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

CBP_MOUSE
NC score	0.035732 (rank : 191)	θ value	0.47712 (rank : 126)
Query Neighborhood Hits	253	Target Neighborhood Hits	1051	Shared Neighborhood Hits	46
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CIR_HUMAN
NC score	0.035471 (rank : 192)	θ value	0.47712 (rank : 127)
Query Neighborhood Hits	253	Target Neighborhood Hits	249	Shared Neighborhood Hits	23
SwissProt Accessions	Q86X95, O95367, Q12804, Q4G1B9, Q6PJI4, Q8IWI2	Gene names	CIR
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor (Recepin).

TDRD5_HUMAN
NC score	0.034925 (rank : 193)	θ value	0.163984 (rank : 116)
Query Neighborhood Hits	253	Target Neighborhood Hits	65	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NAT2, Q5VTV0	Gene names	TDRD5
Domain Architecture
Description	Tudor domain-containing protein 5.

SVIL_MOUSE
NC score	0.034380 (rank : 194)	θ value	0.0431538 (rank : 100)
Query Neighborhood Hits	253	Target Neighborhood Hits	439	Shared Neighborhood Hits	34
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

TAB3_MOUSE
NC score	0.034250 (rank : 195)	θ value	0.813845 (rank : 145)
Query Neighborhood Hits	253	Target Neighborhood Hits	273	Shared Neighborhood Hits	18
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

MYST3_MOUSE
NC score	0.034228 (rank : 196)	θ value	0.62314 (rank : 136)
Query Neighborhood Hits	253	Target Neighborhood Hits	688	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

TAB3_HUMAN
NC score	0.033751 (rank : 197)	θ value	0.163984 (rank : 115)
Query Neighborhood Hits	253	Target Neighborhood Hits	168	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N5C8, Q6VQR0	Gene names	MAP3K7IP3, TAB3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3) (NF-kappa-B-activating protein 1).

ARI1B_HUMAN
NC score	0.032803 (rank : 198)	θ value	0.47712 (rank : 125)
Query Neighborhood Hits	253	Target Neighborhood Hits	567	Shared Neighborhood Hits	34
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

RNC_HUMAN
NC score	0.032685 (rank : 199)	θ value	0.365318 (rank : 124)
Query Neighborhood Hits	253	Target Neighborhood Hits	176	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

TNR6A_HUMAN
NC score	0.032101 (rank : 200)	θ value	0.47712 (rank : 133)
Query Neighborhood Hits	253	Target Neighborhood Hits	343	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

ASXL1_HUMAN
NC score	0.031861 (rank : 201)	θ value	6.88961 (rank : 217)
Query Neighborhood Hits	253	Target Neighborhood Hits	260	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

CCD55_MOUSE
NC score	0.031522 (rank : 202)	θ value	2.36792 (rank : 172)
Query Neighborhood Hits	253	Target Neighborhood Hits	519	Shared Neighborhood Hits	47
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

AUTS2_HUMAN
NC score	0.030299 (rank : 203)	θ value	8.99809 (rank : 232)
Query Neighborhood Hits	253	Target Neighborhood Hits	342	Shared Neighborhood Hits	31
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

NU214_HUMAN
NC score	0.029448 (rank : 204)	θ value	0.47712 (rank : 132)
Query Neighborhood Hits	253	Target Neighborhood Hits	657	Shared Neighborhood Hits	32
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

OGFR_MOUSE
NC score	0.028934 (rank : 205)	θ value	6.88961 (rank : 226)
Query Neighborhood Hits	253	Target Neighborhood Hits	584	Shared Neighborhood Hits	38
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

RERE_MOUSE
NC score	0.028625 (rank : 206)	θ value	1.06291 (rank : 153)
Query Neighborhood Hits	253	Target Neighborhood Hits	785	Shared Neighborhood Hits	40
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

MAP2_MOUSE
NC score	0.027920 (rank : 207)	θ value	5.27518 (rank : 205)
Query Neighborhood Hits	253	Target Neighborhood Hits	342	Shared Neighborhood Hits	31
SwissProt Accessions	P20357	Gene names	Map2, Mtap2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2).

BBX_MOUSE
NC score	0.027326 (rank : 208)	θ value	0.279714 (rank : 119)
Query Neighborhood Hits	253	Target Neighborhood Hits	152	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VBW5, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VI48, Q8VI49, Q8VI50, Q9CS94	Gene names	Bbx, Hbp2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

ICAL_HUMAN
NC score	0.027057 (rank : 209)	θ value	4.03905 (rank : 193)
Query Neighborhood Hits	253	Target Neighborhood Hits	275	Shared Neighborhood Hits	37
SwissProt Accessions	P20810, O95360, Q96D08, Q9H1Z5	Gene names	CAST
Domain Architecture
Description	Calpastatin (Calpain inhibitor) (Sperm BS-17 component).

MYST4_HUMAN
NC score	0.026348 (rank : 210)	θ value	1.81305 (rank : 171)
Query Neighborhood Hits	253	Target Neighborhood Hits	671	Shared Neighborhood Hits	51
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

MADCA_HUMAN
NC score	0.024391 (rank : 211)	θ value	8.99809 (rank : 240)
Query Neighborhood Hits	253	Target Neighborhood Hits	221	Shared Neighborhood Hits	16
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

UBP2L_HUMAN
NC score	0.023955 (rank : 212)	θ value	5.27518 (rank : 211)
Query Neighborhood Hits	253	Target Neighborhood Hits	170	Shared Neighborhood Hits	14
SwissProt Accessions	Q14157, Q5VU75, Q5VU76, Q9BTU3, Q9UGL5	Gene names	UBAP2L, KIAA0144, NICE4
Domain Architecture
Description	Ubiquitin-associated protein 2-like (Protein NICE-4).

ANR11_HUMAN
NC score	0.023870 (rank : 213)	θ value	0.813845 (rank : 138)
Query Neighborhood Hits	253	Target Neighborhood Hits	1289	Shared Neighborhood Hits	64
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

DAXX_MOUSE
NC score	0.023809 (rank : 214)	θ value	4.03905 (rank : 192)
Query Neighborhood Hits	253	Target Neighborhood Hits	173	Shared Neighborhood Hits	16
SwissProt Accessions	O35613, Q9QWT8, Q9QWV3	Gene names	Daxx
Domain Architecture
Description	Death domain-associated protein 6 (Daxx).

NALP5_MOUSE
NC score	0.023768 (rank : 215)	θ value	4.03905 (rank : 195)
Query Neighborhood Hits	253	Target Neighborhood Hits	560	Shared Neighborhood Hits	56
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

ERCC5_HUMAN
NC score	0.023706 (rank : 216)	θ value	1.06291 (rank : 147)
Query Neighborhood Hits	253	Target Neighborhood Hits	162	Shared Neighborhood Hits	23
SwissProt Accessions	P28715, Q7Z2V3, Q8IZL6, Q8N1B7, Q9HD59	Gene names	ERCC5, XPG, XPGC
Domain Architecture
Description	DNA-repair protein complementing XP-G cells (Xeroderma pigmentosum group G-complementing protein) (DNA excision repair protein ERCC-5).

DNMT1_HUMAN
NC score	0.023685 (rank : 217)	θ value	6.88961 (rank : 219)
Query Neighborhood Hits	253	Target Neighborhood Hits	401	Shared Neighborhood Hits	43
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

PRGC2_HUMAN
NC score	0.023412 (rank : 218)	θ value	0.813845 (rank : 143)
Query Neighborhood Hits	253	Target Neighborhood Hits	272	Shared Neighborhood Hits	17
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

MAP2_HUMAN
NC score	0.022629 (rank : 219)	θ value	8.99809 (rank : 241)
Query Neighborhood Hits	253	Target Neighborhood Hits	348	Shared Neighborhood Hits	26
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

UBP2L_MOUSE
NC score	0.022609 (rank : 220)	θ value	5.27518 (rank : 212)
Query Neighborhood Hits	253	Target Neighborhood Hits	173	Shared Neighborhood Hits	15
SwissProt Accessions	Q80X50, Q8BIT6, Q8BIW4, Q8BJ01, Q8CIG7, Q8K102, Q9CRT6	Gene names	Ubap2l
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated protein 2-like.

LPIN2_HUMAN
NC score	0.022440 (rank : 221)	θ value	0.365318 (rank : 123)
Query Neighborhood Hits	253	Target Neighborhood Hits	117	Shared Neighborhood Hits	13
SwissProt Accessions	Q92539	Gene names	LPIN2, KIAA0249
Domain Architecture	No domain graphic available
Description	Lipin-2.

AP3B2_MOUSE
NC score	0.021203 (rank : 222)	θ value	1.06291 (rank : 146)
Query Neighborhood Hits	253	Target Neighborhood Hits	246	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JME5, Q6QR53, Q8R1E5	Gene names	Ap3b2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain).

BAZ2B_HUMAN
NC score	0.021116 (rank : 223)	θ value	1.38821 (rank : 155)
Query Neighborhood Hits	253	Target Neighborhood Hits	803	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

ORC2_HUMAN
NC score	0.020650 (rank : 224)	θ value	1.06291 (rank : 150)
Query Neighborhood Hits	253	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	Q13416, Q13204	Gene names	ORC2L, ORC2
Domain Architecture
Description	Origin recognition complex subunit 2.

MLL3_HUMAN
NC score	0.020522 (rank : 225)	θ value	6.88961 (rank : 225)
Query Neighborhood Hits	253	Target Neighborhood Hits	1644	Shared Neighborhood Hits	63
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

FA13A_MOUSE
NC score	0.020489 (rank : 226)	θ value	0.279714 (rank : 120)
Query Neighborhood Hits	253	Target Neighborhood Hits	83	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BGI4, Q8BZ91	Gene names	Fam13a1, Precm1
Domain Architecture	No domain graphic available
Description	Protein FAM13A1 (Precm1 protein).

ZCH11_HUMAN
NC score	0.020185 (rank : 227)	θ value	3.0926 (rank : 189)
Query Neighborhood Hits	253	Target Neighborhood Hits	278	Shared Neighborhood Hits	24
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

MASTL_MOUSE
NC score	0.020134 (rank : 228)	θ value	1.06291 (rank : 149)
Query Neighborhood Hits	253	Target Neighborhood Hits	862	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C0P0, Q5RJW0, Q6NXX9, Q8BVF3, Q9CZH9, Q9D9V0	Gene names	Mastl
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase-like (EC 2.7.11.1).

PALB2_HUMAN
NC score	0.020032 (rank : 229)	θ value	1.38821 (rank : 157)
Query Neighborhood Hits	253	Target Neighborhood Hits	117	Shared Neighborhood Hits	7
SwissProt Accessions	Q86YC2, Q8N7Y6, Q8ND31, Q9H6W1	Gene names	PALB2
Domain Architecture	No domain graphic available
Description	Partner and localizer of BRCA2.

MYO9B_HUMAN
NC score	0.019951 (rank : 230)	θ value	0.813845 (rank : 142)
Query Neighborhood Hits	253	Target Neighborhood Hits	641	Shared Neighborhood Hits	46
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

MAP9_MOUSE
NC score	0.019646 (rank : 231)	θ value	5.27518 (rank : 206)
Query Neighborhood Hits	253	Target Neighborhood Hits	529	Shared Neighborhood Hits	39
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

K0494_MOUSE
NC score	0.018927 (rank : 232)	θ value	0.813845 (rank : 141)
Query Neighborhood Hits	253	Target Neighborhood Hits	241	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BGQ6, Q3TQN6, Q8BJV7, Q8C0R1	Gene names	Kiaa0494
Domain Architecture	No domain graphic available
Description	Uncharacterized calcium-binding protein KIAA0494.

TITIN_HUMAN
NC score	0.018649 (rank : 233)	θ value	1.38821 (rank : 160)
Query Neighborhood Hits	253	Target Neighborhood Hits	2923	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

JHD2A_MOUSE
NC score	0.018327 (rank : 234)	θ value	1.06291 (rank : 148)
Query Neighborhood Hits	253	Target Neighborhood Hits	123	Shared Neighborhood Hits	12
SwissProt Accessions	Q6PCM1, Q2MJQ6, Q3TKW8, Q3UML3, Q6ZQ57, Q8K2J6, Q8K2K4, Q8R350	Gene names	Jmjd1a, Jhdm2a, Kiaa0742
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2A (EC 1.14.11.-) (Jumonji domain-containing protein 1A).

NDEL1_MOUSE
NC score	0.018152 (rank : 235)	θ value	0.47712 (rank : 131)
Query Neighborhood Hits	253	Target Neighborhood Hits	420	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ERR1, Q9D0Q4, Q9EPT6	Gene names	Ndel1, Nudel
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE-like 1 (Protein Nudel) (Protein mNudE-like) (mNudE-L).

NDEL1_HUMAN
NC score	0.018132 (rank : 236)	θ value	0.47712 (rank : 130)
Query Neighborhood Hits	253	Target Neighborhood Hits	415	Shared Neighborhood Hits	8
SwissProt Accessions	Q9GZM8, Q86T80, Q8TAR7, Q9UH50	Gene names	NDEL1, EOPA, MITAP1, NUDEL
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE-like 1 (Protein Nudel) (Mitosin- associated protein 1).

UBF1_HUMAN
NC score	0.018083 (rank : 237)	θ value	5.27518 (rank : 210)
Query Neighborhood Hits	253	Target Neighborhood Hits	415	Shared Neighborhood Hits	34
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

CKAP2_HUMAN
NC score	0.017962 (rank : 238)	θ value	5.27518 (rank : 201)
Query Neighborhood Hits	253	Target Neighborhood Hits	116	Shared Neighborhood Hits	14
SwissProt Accessions	Q8WWK9, Q3KRA5, Q5VXB4, Q8IWV5, Q8IWV6, Q96FH9, Q9H012, Q9H0D0, Q9H988, Q9HC49, Q9NVG4	Gene names	CKAP2, LB1, TMAP
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 2 (Tumor-associated microtubule- associated protein) (CTCL tumor antigen se20-10).

PCX1_HUMAN
NC score	0.017877 (rank : 239)	θ value	1.38821 (rank : 158)
Query Neighborhood Hits	253	Target Neighborhood Hits	102	Shared Neighborhood Hits	8
SwissProt Accessions	Q96RV3, O94897, Q96AI7, Q9Y2J9	Gene names	PCNX, KIAA0805, KIAA0995, PCNXL1
Domain Architecture
Description	Pecanex-like protein 1 (Pecanex homolog).

AMPH_MOUSE
NC score	0.017765 (rank : 240)	θ value	1.81305 (rank : 161)
Query Neighborhood Hits	253	Target Neighborhood Hits	291	Shared Neighborhood Hits	20
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

FRMD6_HUMAN
NC score	0.017337 (rank : 241)	θ value	0.365318 (rank : 122)
Query Neighborhood Hits	253	Target Neighborhood Hits	60	Shared Neighborhood Hits	5
SwissProt Accessions	Q96NE9, Q5HYF2, Q8N2X1, Q8WUH7	Gene names	FRMD6, C14orf31
Domain Architecture
Description	FERM domain-containing protein 6 (Willin).

CD2L1_MOUSE
NC score	0.016864 (rank : 242)	θ value	0.125558 (rank : 112)
Query Neighborhood Hits	253	Target Neighborhood Hits	1463	Shared Neighborhood Hits	57
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

FGD6_MOUSE
NC score	0.016611 (rank : 243)	θ value	0.62314 (rank : 134)
Query Neighborhood Hits	253	Target Neighborhood Hits	282	Shared Neighborhood Hits	16
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

BNI3L_HUMAN
NC score	0.016414 (rank : 244)	θ value	5.27518 (rank : 198)
Query Neighborhood Hits	253	Target Neighborhood Hits	15	Shared Neighborhood Hits	6
SwissProt Accessions	O60238	Gene names	BNIP3L, BNIP3A, BNIP3H, NIX
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like (NIP3L) (NIP3-like protein X) (BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A).

SPF45_MOUSE
NC score	0.016314 (rank : 245)	θ value	2.36792 (rank : 181)
Query Neighborhood Hits	253	Target Neighborhood Hits	95	Shared Neighborhood Hits	6
SwissProt Accessions	Q8JZX4, O75939	Gene names	Rbm17, Spf45
Domain Architecture
Description	Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17).

BNI3L_MOUSE
NC score	0.016138 (rank : 246)	θ value	5.27518 (rank : 199)
Query Neighborhood Hits	253	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z2F7, Q545J6	Gene names	Bnip3l, Nix
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like (NIP3L) (NIP3-like protein X).

RTN2_HUMAN
NC score	0.015946 (rank : 247)	θ value	1.38821 (rank : 159)
Query Neighborhood Hits	253	Target Neighborhood Hits	59	Shared Neighborhood Hits	5
SwissProt Accessions	O75298, O60509, Q7RTM6, Q7RTN1, Q7RTN2	Gene names	RTN2, NSPL1
Domain Architecture
Description	Reticulon-2 (Neuroendocrine-specific protein-like 1) (NSP-like protein 1) (NSPLI).

PHC3_MOUSE
NC score	0.015748 (rank : 248)	θ value	2.36792 (rank : 179)
Query Neighborhood Hits	253	Target Neighborhood Hits	194	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CHP6, Q3TLV5	Gene names	Phc3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3.

NSD1_MOUSE
NC score	0.015612 (rank : 249)	θ value	8.99809 (rank : 244)
Query Neighborhood Hits	253	Target Neighborhood Hits	472	Shared Neighborhood Hits	32
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

CRCM_HUMAN
NC score	0.015533 (rank : 250)	θ value	2.36792 (rank : 173)
Query Neighborhood Hits	253	Target Neighborhood Hits	520	Shared Neighborhood Hits	16
SwissProt Accessions	P23508	Gene names	MCC
Domain Architecture
Description	Colorectal mutant cancer protein (Protein MCC).

NUDC_MOUSE
NC score	0.013736 (rank : 251)	θ value	3.0926 (rank : 186)
Query Neighborhood Hits	253	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	O35685, Q3UJS7	Gene names	Nudc
Domain Architecture	No domain graphic available
Description	Nuclear migration protein nudC (Nuclear distribution protein C homolog) (Silica-induced gene 92 protein) (SIG-92).

SSBP4_HUMAN
NC score	0.013565 (rank : 252)	θ value	6.88961 (rank : 228)
Query Neighborhood Hits	253	Target Neighborhood Hits	753	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

S3TC1_HUMAN
NC score	0.013113 (rank : 253)	θ value	5.27518 (rank : 209)
Query Neighborhood Hits	253	Target Neighborhood Hits	78	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TE82	Gene names	SH3TC1
Domain Architecture	No domain graphic available
Description	SH3 domain and tetratricopeptide repeats-containing protein 1.

ZGPAT_HUMAN
NC score	0.013005 (rank : 254)	θ value	3.0926 (rank : 190)
Query Neighborhood Hits	253	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N5A5, Q5JWI9, Q8NC55, Q96JI0, Q96JU4, Q9H401	Gene names	ZGPAT, KIAA1847, ZC3H9, ZC3HDC9
Domain Architecture
Description	Zinc finger CCCH-type with G patch domain protein (Zinc finger CCCH domain-containing protein 9).

DCX_MOUSE
NC score	0.012752 (rank : 255)	θ value	2.36792 (rank : 174)
Query Neighborhood Hits	253	Target Neighborhood Hits	124	Shared Neighborhood Hits	14
SwissProt Accessions	O88809	Gene names	Dcx, Dcn
Domain Architecture
Description	Neuronal migration protein doublecortin (Lissencephalin-X) (Lis-X) (Doublin).

LAT_HUMAN
NC score	0.012648 (rank : 256)	θ value	6.88961 (rank : 224)
Query Neighborhood Hits	253	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	O43561, O43919	Gene names	LAT
Domain Architecture	No domain graphic available
Description	Linker for activation of T-cells family member 1 (36 kDa phospho- tyrosine adapter protein) (pp36) (p36-38).

AP3D1_MOUSE
NC score	0.012237 (rank : 257)	θ value	1.81305 (rank : 162)
Query Neighborhood Hits	253	Target Neighborhood Hits	144	Shared Neighborhood Hits	13
SwissProt Accessions	O54774	Gene names	Ap3d1, Ap3d
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin) (mBLVR1).

NUPL2_HUMAN
NC score	0.011865 (rank : 258)	θ value	5.27518 (rank : 208)
Query Neighborhood Hits	253	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	O15504, Q49AE7, Q9BS49	Gene names	NUPL2, CG1
Domain Architecture	No domain graphic available
Description	Nucleoporin-like 2 (NLP-1) (hCG1) (NUP42 homolog).

TM16H_HUMAN
NC score	0.011855 (rank : 259)	θ value	8.99809 (rank : 250)
Query Neighborhood Hits	253	Target Neighborhood Hits	139	Shared Neighborhood Hits	9
SwissProt Accessions	Q9HCE9	Gene names	TMEM16H, KIAA1623
Domain Architecture	No domain graphic available
Description	Transmembrane protein 16H.

FGD6_HUMAN
NC score	0.011726 (rank : 260)	θ value	6.88961 (rank : 220)
Query Neighborhood Hits	253	Target Neighborhood Hits	237	Shared Neighborhood Hits	16
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

NFM_MOUSE
NC score	0.011641 (rank : 261)	θ value	8.99809 (rank : 243)
Query Neighborhood Hits	253	Target Neighborhood Hits	1159	Shared Neighborhood Hits	64
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

HBP1_MOUSE
NC score	0.010275 (rank : 262)	θ value	3.0926 (rank : 185)
Query Neighborhood Hits	253	Target Neighborhood Hits	86	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R316, Q3V0I4, Q8BUS3, Q8C199	Gene names	Hbp1
Domain Architecture	No domain graphic available
Description	HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1).

ANR12_HUMAN
NC score	0.010239 (rank : 263)	θ value	1.38821 (rank : 154)
Query Neighborhood Hits	253	Target Neighborhood Hits	1081	Shared Neighborhood Hits	44
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

HES6_MOUSE
NC score	0.010220 (rank : 264)	θ value	6.88961 (rank : 223)
Query Neighborhood Hits	253	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JHE6, Q3U2D7	Gene names	Hes6
Domain Architecture	No domain graphic available
Description	Transcription cofactor HES-6 (Hairy and enhancer of split 6).

HES6_HUMAN
NC score	0.010132 (rank : 265)	θ value	6.88961 (rank : 222)
Query Neighborhood Hits	253	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q96HZ4, Q8N2J2, Q96T93, Q9P2S3	Gene names	HES6
Domain Architecture	No domain graphic available
Description	Transcription cofactor HES-6 (Hairy and enhancer of split 6) (C- HAIRY1).

WNK4_MOUSE
NC score	0.009541 (rank : 266)	θ value	8.99809 (rank : 253)
Query Neighborhood Hits	253	Target Neighborhood Hits	961	Shared Neighborhood Hits	22
SwissProt Accessions	Q80UE6, Q4VAC1, Q80XB5, Q80XN2, Q8R0N0, Q8R340	Gene names	Wnk4, Prkwnk4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

ARP5_MOUSE
NC score	0.009307 (rank : 267)	θ value	1.81305 (rank : 163)
Query Neighborhood Hits	253	Target Neighborhood Hits	116	Shared Neighborhood Hits	2
SwissProt Accessions	Q80US4, Q8BL26	Gene names	Actr5
Domain Architecture	No domain graphic available
Description	Actin-related protein 5.

BRPF3_HUMAN
NC score	0.009046 (rank : 268)	θ value	5.27518 (rank : 200)
Query Neighborhood Hits	253	Target Neighborhood Hits	217	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

EFG2_MOUSE
NC score	0.008771 (rank : 269)	θ value	3.0926 (rank : 184)
Query Neighborhood Hits	253	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R2Q4	Gene names	Gfm2, Efg2
Domain Architecture
Description	Elongation factor G 2, mitochondrial precursor (mEF-G 2) (Elongation factor G2).

MYPT1_MOUSE
NC score	0.008736 (rank : 270)	θ value	8.99809 (rank : 242)
Query Neighborhood Hits	253	Target Neighborhood Hits	539	Shared Neighborhood Hits	30
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

GPTC2_MOUSE
NC score	0.008580 (rank : 271)	θ value	6.88961 (rank : 221)
Query Neighborhood Hits	253	Target Neighborhood Hits	61	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TQC7, Q8BNJ9, Q8BPM1, Q8CDH9	Gene names	Gpatc2
Domain Architecture
Description	G patch domain-containing protein 2.

UBP8_HUMAN
NC score	0.008540 (rank : 272)	θ value	5.27518 (rank : 213)
Query Neighborhood Hits	253	Target Neighborhood Hits	751	Shared Neighborhood Hits	36
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

CEP68_MOUSE
NC score	0.008026 (rank : 273)	θ value	8.99809 (rank : 235)
Query Neighborhood Hits	253	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C0D9, Q3US49, Q5SW85, Q8R2V0	Gene names	Cep68
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 68 kDa (Cep68 protein).

SOS1_HUMAN
NC score	0.007736 (rank : 274)	θ value	6.88961 (rank : 227)
Query Neighborhood Hits	253	Target Neighborhood Hits	274	Shared Neighborhood Hits	11
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

LRC50_HUMAN
NC score	0.007521 (rank : 275)	θ value	8.99809 (rank : 239)
Query Neighborhood Hits	253	Target Neighborhood Hits	275	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NEP3, Q69YI8, Q69YJ0, Q96LP3	Gene names	LRRC50
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 50.

PZRN3_MOUSE
NC score	0.007486 (rank : 276)	θ value	2.36792 (rank : 180)
Query Neighborhood Hits	253	Target Neighborhood Hits	447	Shared Neighborhood Hits	13
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

ILDR1_HUMAN
NC score	0.007476 (rank : 277)	θ value	8.99809 (rank : 237)
Query Neighborhood Hits	253	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q86SU0, Q6ZP61, Q7Z578	Gene names	ILDR1
Domain Architecture	No domain graphic available
Description	Immunoglobulin-like domain-containing receptor 1 precursor.

RBP26_HUMAN
NC score	0.007453 (rank : 278)	θ value	4.03905 (rank : 196)
Query Neighborhood Hits	253	Target Neighborhood Hits	146	Shared Neighborhood Hits	12
SwissProt Accessions	Q68DN6, Q6V1X0	Gene names	RANBP2L6
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 6 (RanBP2L6).

JHD1B_MOUSE
NC score	0.007423 (rank : 279)	θ value	5.27518 (rank : 204)
Query Neighborhood Hits	253	Target Neighborhood Hits	214	Shared Neighborhood Hits	18
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

LYST_HUMAN
NC score	0.007265 (rank : 280)	θ value	2.36792 (rank : 177)
Query Neighborhood Hits	253	Target Neighborhood Hits	324	Shared Neighborhood Hits	11
SwissProt Accessions	Q99698, O43274, Q5T2U9, Q96TD7, Q96TD8, Q99709, Q9H133	Gene names	LYST, CHS, CHS1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige homolog).

ASPM_HUMAN
NC score	0.007223 (rank : 281)	θ value	6.88961 (rank : 216)
Query Neighborhood Hits	253	Target Neighborhood Hits	197	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IZT6, Q86UX4, Q8IUL2, Q8IZJ7, Q8IZJ8, Q8IZJ9, Q8N4D1, Q9NVS1, Q9NVT6	Gene names	ASPM, MCPH5
Domain Architecture
Description	Abnormal spindle-like microcephaly-associated protein (Abnormal spindle protein homolog) (Asp homolog).

TXLNB_HUMAN
NC score	0.006910 (rank : 282)	θ value	8.99809 (rank : 252)
Query Neighborhood Hits	253	Target Neighborhood Hits	912	Shared Neighborhood Hits	42
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

HS105_MOUSE
NC score	0.006388 (rank : 283)	θ value	2.36792 (rank : 176)
Query Neighborhood Hits	253	Target Neighborhood Hits	129	Shared Neighborhood Hits	11
SwissProt Accessions	Q61699, Q3TNS2, Q3UIY8, Q62578, Q62579, Q6A0A5, Q8C430, Q8VCW6	Gene names	Hsph1, Hsp105, Hsp110, Kiaa0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock-related 100 kDa protein E7I) (HSP-E7I) (Heat shock 110 kDa protein) (42 degrees C-HSP).

PCIF1_HUMAN
NC score	0.005983 (rank : 284)	θ value	8.99809 (rank : 247)
Query Neighborhood Hits	253	Target Neighborhood Hits	92	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H4Z3, Q9NT85	Gene names	PCIF1, C20orf67
Domain Architecture
Description	Phosphorylated CTD-interacting factor 1.

TRHY_HUMAN
NC score	0.005901 (rank : 285)	θ value	4.03905 (rank : 197)
Query Neighborhood Hits	253	Target Neighborhood Hits	1385	Shared Neighborhood Hits	51
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

AAKG2_MOUSE
NC score	0.005889 (rank : 286)	θ value	8.99809 (rank : 231)
Query Neighborhood Hits	253	Target Neighborhood Hits	53	Shared Neighborhood Hits	7
SwissProt Accessions	Q91WG5, Q6V7V5	Gene names	Prkag2
Domain Architecture	No domain graphic available
Description	5'-AMP-activated protein kinase subunit gamma-2 (AMPK gamma-2 chain) (AMPK gamma2).

UBP24_HUMAN
NC score	0.005778 (rank : 287)	θ value	3.0926 (rank : 187)
Query Neighborhood Hits	253	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPU5, Q6ZSY2, Q8N2Y4, Q9NXD1	Gene names	USP24, KIAA1057
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.1.2.15) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) (Deubiquitinating enzyme 24).

TOX_HUMAN
NC score	0.005761 (rank : 288)	θ value	8.99809 (rank : 251)
Query Neighborhood Hits	253	Target Neighborhood Hits	106	Shared Neighborhood Hits	7
SwissProt Accessions	O94900, Q96AV5	Gene names	TOX, KIAA0808
Domain Architecture	No domain graphic available
Description	Thymus high mobility group box protein TOX.

UB2J1_HUMAN
NC score	0.004306 (rank : 289)	θ value	6.88961 (rank : 230)
Query Neighborhood Hits	253	Target Neighborhood Hits	61	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y385, Q5W0N4, Q9BZ32, Q9NQL3, Q9NY66, Q9P011, Q9P0S0, Q9UF10	Gene names	UBE2J1, NCUBE1
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 J1 (EC 6.3.2.19) (Non-canonical ubiquitin-conjugating enzyme 1) (NCUBE1) (Yeast ubiquitin-conjugating enzyme UBC6 homolog E) (HSUBC6e).

GCC2_MOUSE
NC score	0.003975 (rank : 290)	θ value	8.99809 (rank : 236)
Query Neighborhood Hits	253	Target Neighborhood Hits	1619	Shared Neighborhood Hits	42
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

PTPRG_MOUSE
NC score	0.003778 (rank : 291)	θ value	8.99809 (rank : 248)
Query Neighborhood Hits	253	Target Neighborhood Hits	260	Shared Neighborhood Hits	19
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

OSBL5_HUMAN
NC score	0.003629 (rank : 292)	θ value	8.99809 (rank : 245)
Query Neighborhood Hits	253	Target Neighborhood Hits	117	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H0X9, Q9BZB0, Q9P1Z4	Gene names	OSBPL5, KIAA1534, ORP5
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5).

B3A2_HUMAN
NC score	0.003524 (rank : 293)	θ value	8.99809 (rank : 233)
Query Neighborhood Hits	253	Target Neighborhood Hits	57	Shared Neighborhood Hits	6
SwissProt Accessions	P04920, Q45EY5, Q969L3	Gene names	SLC4A2, AE2, EPB3L1, HKB3, MPB3L
Domain Architecture
Description	Anion exchange protein 2 (Non-erythroid band 3-like protein) (AE2 anion exchanger) (Solute carrier family 4 member 2) (BND3L).

TS1R2_HUMAN
NC score	0.002255 (rank : 294)	θ value	6.88961 (rank : 229)
Query Neighborhood Hits	253	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TE23, Q5TZ19	Gene names	TAS1R2, GPR71, T1R2, TR2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).

ADA30_HUMAN
NC score	0.002016 (rank : 295)	θ value	6.88961 (rank : 215)
Query Neighborhood Hits	253	Target Neighborhood Hits	391	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

KCNB2_HUMAN
NC score	0.000479 (rank : 296)	θ value	8.99809 (rank : 238)
Query Neighborhood Hits	253	Target Neighborhood Hits	212	Shared Neighborhood Hits	7
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

PCDGF_HUMAN
NC score	-0.001054 (rank : 297)	θ value	2.36792 (rank : 178)
Query Neighborhood Hits	253	Target Neighborhood Hits	162	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5G1, Q9Y5C7	Gene names	PCDHGB3
Domain Architecture
Description	Protocadherin gamma B3 precursor (PCDH-gamma-B3).

SUHW1_HUMAN
NC score	-0.004366 (rank : 298)	θ value	8.99809 (rank : 249)
Query Neighborhood Hits	253	Target Neighborhood Hits	648	Shared Neighborhood Hits	8
SwissProt Accessions	P59817	Gene names	SUHW1
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 1 (3'OY11.1).

HELI_MOUSE
NC score	-0.007365 (rank : 299)	θ value	5.27518 (rank : 202)
Query Neighborhood Hits	253	Target Neighborhood Hits	746	Shared Neighborhood Hits	8
SwissProt Accessions	P81183	Gene names	Ikzf2, Helios, Zfpn1a2, Znfn1a2
Domain Architecture	No domain graphic available
Description	Zinc finger protein Helios (IKAROS family zinc finger protein 2).