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Network neighborhood for query Sequence : WWP1_HUMAN

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WWP1_HUMAN
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ITCH_HUMAN
θ value	0 (rank : 1)	NC score	0.976085 (rank : 6)
Query Neighborhood Hits	262	Target Neighborhood Hits	162	Shared Neighborhood Hits	84
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

ITCH_MOUSE
θ value	0 (rank : 2)	NC score	0.983097 (rank : 4)
Query Neighborhood Hits	262	Target Neighborhood Hits	127	Shared Neighborhood Hits	80
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

WWP1_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	262	Target Neighborhood Hits	262	Shared Neighborhood Hits	262
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

WWP1_MOUSE
θ value	0 (rank : 4)	NC score	0.988077 (rank : 2)
Query Neighborhood Hits	262	Target Neighborhood Hits	138	Shared Neighborhood Hits	100
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

WWP2_HUMAN
θ value	0 (rank : 5)	NC score	0.982917 (rank : 5)
Query Neighborhood Hits	262	Target Neighborhood Hits	177	Shared Neighborhood Hits	98
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

WWP2_MOUSE
θ value	0 (rank : 6)	NC score	0.983562 (rank : 3)
Query Neighborhood Hits	262	Target Neighborhood Hits	118	Shared Neighborhood Hits	80
SwissProt Accessions	Q9DBH0, Q8BTG4, Q923F6	Gene names	Wwp2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2).

NED4L_MOUSE
θ value	5.9766e-145 (rank : 7)	NC score	0.892687 (rank : 12)
Query Neighborhood Hits	262	Target Neighborhood Hits	231	Shared Neighborhood Hits	87
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NED4L_HUMAN
θ value	1.12714e-143 (rank : 8)	NC score	0.891907 (rank : 13)
Query Neighborhood Hits	262	Target Neighborhood Hits	238	Shared Neighborhood Hits	88
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NEDD4_HUMAN
θ value	3.27947e-143 (rank : 9)	NC score	0.906844 (rank : 11)
Query Neighborhood Hits	262	Target Neighborhood Hits	214	Shared Neighborhood Hits	85
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

SMUF2_HUMAN
θ value	3.88293e-136 (rank : 10)	NC score	0.952988 (rank : 7)
Query Neighborhood Hits	262	Target Neighborhood Hits	142	Shared Neighborhood Hits	77
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

NEDD4_MOUSE
θ value	1.4755e-135 (rank : 11)	NC score	0.910203 (rank : 10)
Query Neighborhood Hits	262	Target Neighborhood Hits	212	Shared Neighborhood Hits	88
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

SMUF1_MOUSE
θ value	7.33985e-127 (rank : 12)	NC score	0.945746 (rank : 8)
Query Neighborhood Hits	262	Target Neighborhood Hits	142	Shared Neighborhood Hits	67
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

SMUF1_HUMAN
θ value	1.38424e-125 (rank : 13)	NC score	0.942545 (rank : 9)
Query Neighborhood Hits	262	Target Neighborhood Hits	135	Shared Neighborhood Hits	64
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

HUWE1_HUMAN
θ value	7.93343e-89 (rank : 14)	NC score	0.863292 (rank : 20)
Query Neighborhood Hits	262	Target Neighborhood Hits	443	Shared Neighborhood Hits	70
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

HUWE1_MOUSE
θ value	7.93343e-89 (rank : 15)	NC score	0.864459 (rank : 19)
Query Neighborhood Hits	262	Target Neighborhood Hits	406	Shared Neighborhood Hits	72
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

HECD2_MOUSE
θ value	9.16162e-53 (rank : 16)	NC score	0.875277 (rank : 14)
Query Neighborhood Hits	262	Target Neighborhood Hits	38	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CDU6, Q8CBQ9	Gene names	Hectd2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

UBE3A_HUMAN
θ value	1.32293e-51 (rank : 17)	NC score	0.867973 (rank : 16)
Query Neighborhood Hits	262	Target Neighborhood Hits	49	Shared Neighborhood Hits	33
SwissProt Accessions	Q05086, P78355, Q93066, Q9UEP4, Q9UEP5, Q9UEP6, Q9UEP7, Q9UEP8, Q9UEP9	Gene names	UBE3A, E6AP
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Oncogenic protein-associated protein E6-AP) (Human papillomavirus E6-associated protein) (NY-REN-54 antigen).

HECD2_HUMAN
θ value	6.56568e-51 (rank : 18)	NC score	0.872417 (rank : 15)
Query Neighborhood Hits	262	Target Neighborhood Hits	41	Shared Neighborhood Hits	33
SwissProt Accessions	Q5U5R9, Q5VZ97, Q5VZ99, Q8TCP5	Gene names	HECTD2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

UBE3A_MOUSE
θ value	6.35935e-46 (rank : 19)	NC score	0.861364 (rank : 21)
Query Neighborhood Hits	262	Target Neighborhood Hits	47	Shared Neighborhood Hits	34
SwissProt Accessions	O08759, P97482	Gene names	Ube3a
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (Oncogenic protein- associated protein E6-AP).

K0317_HUMAN
θ value	1.08474e-45 (rank : 20)	NC score	0.867609 (rank : 17)
Query Neighborhood Hits	262	Target Neighborhood Hits	46	Shared Neighborhood Hits	34
SwissProt Accessions	O15033, Q7LDY1, Q8IYY9	Gene names	KIAA0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

K0317_MOUSE
θ value	4.122e-45 (rank : 21)	NC score	0.866963 (rank : 18)
Query Neighborhood Hits	262	Target Neighborhood Hits	43	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CHG5, Q6P9Q1, Q80YC4, Q8C5W5	Gene names	Kiaa0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

UBE3C_HUMAN
θ value	4.2656e-42 (rank : 22)	NC score	0.849878 (rank : 22)
Query Neighborhood Hits	262	Target Neighborhood Hits	51	Shared Neighborhood Hits	33
SwissProt Accessions	Q15386, Q8TC15, Q96CR4, Q9UDU3	Gene names	UBE3C, KIAA0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

UBE3C_MOUSE
θ value	3.61106e-41 (rank : 23)	NC score	0.848290 (rank : 23)
Query Neighborhood Hits	262	Target Neighborhood Hits	48	Shared Neighborhood Hits	33
SwissProt Accessions	Q80U95, Q8BQZ6, Q8C7W6, Q8CDJ1, Q8VDL5	Gene names	Ube3c, Kiaa0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

HERC3_HUMAN
θ value	6.81017e-40 (rank : 24)	NC score	0.718958 (rank : 26)
Query Neighborhood Hits	262	Target Neighborhood Hits	62	Shared Neighborhood Hits	33
SwissProt Accessions	Q15034	Gene names	HERC3, KIAA0032
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain protein 3.

HERC2_MOUSE
θ value	5.22648e-32 (rank : 25)	NC score	0.615190 (rank : 31)
Query Neighborhood Hits	262	Target Neighborhood Hits	167	Shared Neighborhood Hits	40
SwissProt Accessions	Q4U2R1, O88473, Q3TRJ8, Q3TS47, Q3TST2, Q3UFQ6, Q3URH7, Q5DU32, Q7TPR5, Q80VV7, Q9QYT1, Q9Z168, Q9Z171	Gene names	Herc2, jdf2, Kiaa0393, rjs
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

TRIPC_HUMAN
θ value	1.52067e-31 (rank : 26)	NC score	0.789175 (rank : 24)
Query Neighborhood Hits	262	Target Neighborhood Hits	319	Shared Neighborhood Hits	56
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

HERC2_HUMAN
θ value	2.59387e-31 (rank : 27)	NC score	0.611025 (rank : 32)
Query Neighborhood Hits	262	Target Neighborhood Hits	163	Shared Neighborhood Hits	41
SwissProt Accessions	O95714, Q86SV7, Q86SV8, Q86SV9, Q86YY3, Q86YY4, Q86YY5, Q86YY6, Q86YY7, Q86YY8, Q86YY9, Q86YZ0, Q86YZ1	Gene names	HERC2
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

HERC5_HUMAN
θ value	7.54701e-31 (rank : 28)	NC score	0.722384 (rank : 25)
Query Neighborhood Hits	262	Target Neighborhood Hits	66	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UII4	Gene names	HERC5, CEB1, CEBP1
Domain Architecture
Description	HECT domain and RCC1-like domain-containing protein 5 (Cyclin-E- binding protein 1).

HECD1_HUMAN
θ value	8.08199e-25 (rank : 29)	NC score	0.558530 (rank : 33)
Query Neighborhood Hits	262	Target Neighborhood Hits	371	Shared Neighborhood Hits	35
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

HECD3_MOUSE
θ value	9.90251e-15 (rank : 30)	NC score	0.684342 (rank : 27)
Query Neighborhood Hits	262	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	Q3U487, Q3TN76, Q641P3, Q8BQ74, Q8R1L6	Gene names	Hectd3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

HECD3_HUMAN
θ value	4.91457e-14 (rank : 31)	NC score	0.678926 (rank : 28)
Query Neighborhood Hits	262	Target Neighborhood Hits	49	Shared Neighborhood Hits	33
SwissProt Accessions	Q5T447, Q5T448, Q9H783	Gene names	HECTD3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

YAP1_MOUSE
θ value	8.38298e-14 (rank : 32)	NC score	0.553415 (rank : 34)
Query Neighborhood Hits	262	Target Neighborhood Hits	96	Shared Neighborhood Hits	55
SwissProt Accessions	P46938, Q52KJ5	Gene names	Yap1, Yap, Yap65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

EDD1_HUMAN
θ value	1.09485e-13 (rank : 33)	NC score	0.643339 (rank : 30)
Query Neighborhood Hits	262	Target Neighborhood Hits	170	Shared Neighborhood Hits	39
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

EDD1_MOUSE
θ value	1.09485e-13 (rank : 34)	NC score	0.645148 (rank : 29)
Query Neighborhood Hits	262	Target Neighborhood Hits	167	Shared Neighborhood Hits	41
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

WWC1_HUMAN
θ value	7.09661e-13 (rank : 35)	NC score	0.443207 (rank : 38)
Query Neighborhood Hits	262	Target Neighborhood Hits	290	Shared Neighborhood Hits	50
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

WWC1_MOUSE
θ value	7.09661e-13 (rank : 36)	NC score	0.442147 (rank : 39)
Query Neighborhood Hits	262	Target Neighborhood Hits	290	Shared Neighborhood Hits	44
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

MAGI2_MOUSE
θ value	1.02475e-11 (rank : 37)	NC score	0.321779 (rank : 48)
Query Neighborhood Hits	262	Target Neighborhood Hits	370	Shared Neighborhood Hits	62
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

WWOX_HUMAN
θ value	1.02475e-11 (rank : 38)	NC score	0.392790 (rank : 40)
Query Neighborhood Hits	262	Target Neighborhood Hits	115	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NZC7, Q5MYT5, Q96KM3, Q96RF2, Q9BTT8, Q9NPC9, Q9NRF4, Q9NRF5, Q9NRF6, Q9NRK1, Q9NZC5	Gene names	WWOX, FOR, WOX1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-) (Fragile site FRA16D oxidoreductase).

WWOX_MOUSE
θ value	1.02475e-11 (rank : 39)	NC score	0.389404 (rank : 41)
Query Neighborhood Hits	262	Target Neighborhood Hits	118	Shared Neighborhood Hits	49
SwissProt Accessions	Q91WL8, Q8C8J6, Q920Y2, Q9D2B3, Q9D339, Q9JLF5	Gene names	Wwox, Wox1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-).

SAV1_HUMAN
θ value	1.74796e-11 (rank : 40)	NC score	0.528632 (rank : 35)
Query Neighborhood Hits	262	Target Neighborhood Hits	51	Shared Neighborhood Hits	43
SwissProt Accessions	Q9H4B6, Q6IA58, Q9H949, Q9HAK9	Gene names	SAV1, WW45
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (hWW45).

SAV1_MOUSE
θ value	1.74796e-11 (rank : 41)	NC score	0.528156 (rank : 36)
Query Neighborhood Hits	262	Target Neighborhood Hits	48	Shared Neighborhood Hits	41
SwissProt Accessions	Q8VEB2, Q9D9N9, Q9ER46	Gene names	Sav1, Ww45, Wwp3
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (mWW45).

MAGI1_MOUSE
θ value	1.133e-10 (rank : 42)	NC score	0.300761 (rank : 52)
Query Neighborhood Hits	262	Target Neighborhood Hits	403	Shared Neighborhood Hits	66
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

MAGI1_HUMAN
θ value	1.47974e-10 (rank : 43)	NC score	0.301216 (rank : 51)
Query Neighborhood Hits	262	Target Neighborhood Hits	388	Shared Neighborhood Hits	61
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

MAGI2_HUMAN
θ value	1.25267e-09 (rank : 44)	NC score	0.306662 (rank : 50)
Query Neighborhood Hits	262	Target Neighborhood Hits	373	Shared Neighborhood Hits	55
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

PKHA5_HUMAN
θ value	1.63604e-09 (rank : 45)	NC score	0.285841 (rank : 53)
Query Neighborhood Hits	262	Target Neighborhood Hits	455	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

BAG3_HUMAN
θ value	3.77169e-06 (rank : 46)	NC score	0.355536 (rank : 47)
Query Neighborhood Hits	262	Target Neighborhood Hits	314	Shared Neighborhood Hits	63
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

PRP40_HUMAN
θ value	6.43352e-06 (rank : 47)	NC score	0.227087 (rank : 57)
Query Neighborhood Hits	262	Target Neighborhood Hits	442	Shared Neighborhood Hits	54
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

PRP40_MOUSE
θ value	6.43352e-06 (rank : 48)	NC score	0.228231 (rank : 56)
Query Neighborhood Hits	262	Target Neighborhood Hits	447	Shared Neighborhood Hits	60
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

BAG3_MOUSE
θ value	2.44474e-05 (rank : 49)	NC score	0.313675 (rank : 49)
Query Neighborhood Hits	262	Target Neighborhood Hits	513	Shared Neighborhood Hits	83
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

WWTR1_HUMAN
θ value	7.1131e-05 (rank : 50)	NC score	0.376999 (rank : 46)
Query Neighborhood Hits	262	Target Neighborhood Hits	76	Shared Neighborhood Hits	46
SwissProt Accessions	Q9GZV5, Q8N3P2, Q9Y3W6	Gene names	WWTR1, TAZ
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

WWTR1_MOUSE
θ value	7.1131e-05 (rank : 51)	NC score	0.379666 (rank : 44)
Query Neighborhood Hits	262	Target Neighborhood Hits	54	Shared Neighborhood Hits	41
SwissProt Accessions	Q9EPK5, Q99KI4	Gene names	Wwtr1, Taz
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

YAP1_HUMAN
θ value	7.1131e-05 (rank : 52)	NC score	0.377542 (rank : 45)
Query Neighborhood Hits	262	Target Neighborhood Hits	173	Shared Neighborhood Hits	66
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

GAS7_HUMAN
θ value	9.29e-05 (rank : 53)	NC score	0.264976 (rank : 54)
Query Neighborhood Hits	262	Target Neighborhood Hits	258	Shared Neighborhood Hits	51
SwissProt Accessions	O60861, O43144	Gene names	GAS7, KIAA0394
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

GAS7_MOUSE
θ value	0.000158464 (rank : 54)	NC score	0.264252 (rank : 55)
Query Neighborhood Hits	262	Target Neighborhood Hits	259	Shared Neighborhood Hits	50
SwissProt Accessions	Q60780, Q9QY25, Q9QY26, Q9QY34	Gene names	Gas7
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

PINL_HUMAN
θ value	0.00020696 (rank : 55)	NC score	0.444130 (rank : 37)
Query Neighborhood Hits	262	Target Neighborhood Hits	47	Shared Neighborhood Hits	44
SwissProt Accessions	O15428	Gene names	PIN1L
Domain Architecture
Description	PIN1-like protein.

PIN1_HUMAN
θ value	0.000270298 (rank : 56)	NC score	0.379889 (rank : 43)
Query Neighborhood Hits	262	Target Neighborhood Hits	59	Shared Neighborhood Hits	43
SwissProt Accessions	Q13526	Gene names	PIN1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

PIN1_MOUSE
θ value	0.000270298 (rank : 57)	NC score	0.381806 (rank : 42)
Query Neighborhood Hits	262	Target Neighborhood Hits	60	Shared Neighborhood Hits	46
SwissProt Accessions	Q9QUR7, Q543B3	Gene names	Pin1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

APBB2_HUMAN
θ value	0.00035302 (rank : 58)	NC score	0.180191 (rank : 58)
Query Neighborhood Hits	262	Target Neighborhood Hits	96	Shared Neighborhood Hits	40
SwissProt Accessions	Q92870, Q8IUI6	Gene names	APBB2, FE65L, FE65L1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2 (Fe65-like protein).

APBB2_MOUSE
θ value	0.00035302 (rank : 59)	NC score	0.169774 (rank : 61)
Query Neighborhood Hits	262	Target Neighborhood Hits	88	Shared Neighborhood Hits	36
SwissProt Accessions	Q9DBR4, Q6DFX8	Gene names	Apbb2
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2.

PAPOA_HUMAN
θ value	0.000602161 (rank : 60)	NC score	0.033399 (rank : 165)
Query Neighborhood Hits	262	Target Neighborhood Hits	75	Shared Neighborhood Hits	13
SwissProt Accessions	P51003, Q86SX4, Q86TV0, Q8IYF5, Q9BVU2	Gene names	PAPOLA, PAP
Domain Architecture	No domain graphic available
Description	Poly(A) polymerase alpha (EC 2.7.7.19) (PAP) (Polynucleotide adenylyltransferase alpha).

MUC13_MOUSE
θ value	0.00102713 (rank : 61)	NC score	0.063204 (rank : 107)
Query Neighborhood Hits	262	Target Neighborhood Hits	447	Shared Neighborhood Hits	42
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

MUC1_MOUSE
θ value	0.00102713 (rank : 62)	NC score	0.063575 (rank : 106)
Query Neighborhood Hits	262	Target Neighborhood Hits	388	Shared Neighborhood Hits	57
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

RHG12_MOUSE
θ value	0.00102713 (rank : 63)	NC score	0.123610 (rank : 65)
Query Neighborhood Hits	262	Target Neighborhood Hits	204	Shared Neighborhood Hits	38
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

CEND1_HUMAN
θ value	0.00175202 (rank : 64)	NC score	0.022717 (rank : 204)
Query Neighborhood Hits	262	Target Neighborhood Hits	284	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

STXB4_HUMAN
θ value	0.00298849 (rank : 65)	NC score	0.177316 (rank : 60)
Query Neighborhood Hits	262	Target Neighborhood Hits	616	Shared Neighborhood Hits	52
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

STXB4_MOUSE
θ value	0.00298849 (rank : 66)	NC score	0.178384 (rank : 59)
Query Neighborhood Hits	262	Target Neighborhood Hits	629	Shared Neighborhood Hits	53
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

LAD1_MOUSE
θ value	0.00509761 (rank : 67)	NC score	0.046861 (rank : 155)
Query Neighborhood Hits	262	Target Neighborhood Hits	391	Shared Neighborhood Hits	46
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

MKL1_HUMAN
θ value	0.00509761 (rank : 68)	NC score	0.027387 (rank : 186)
Query Neighborhood Hits	262	Target Neighborhood Hits	232	Shared Neighborhood Hits	19
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

TCRG1_MOUSE
θ value	0.00665767 (rank : 69)	NC score	0.095414 (rank : 72)
Query Neighborhood Hits	262	Target Neighborhood Hits	947	Shared Neighborhood Hits	82
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TCRG1_HUMAN
θ value	0.00869519 (rank : 70)	NC score	0.095198 (rank : 73)
Query Neighborhood Hits	262	Target Neighborhood Hits	929	Shared Neighborhood Hits	76
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

GNAS1_MOUSE
θ value	0.0113563 (rank : 71)	NC score	0.019095 (rank : 222)
Query Neighborhood Hits	262	Target Neighborhood Hits	651	Shared Neighborhood Hits	49
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

RD23B_MOUSE
θ value	0.0113563 (rank : 72)	NC score	0.040713 (rank : 159)
Query Neighborhood Hits	262	Target Neighborhood Hits	189	Shared Neighborhood Hits	21
SwissProt Accessions	P54728	Gene names	Rad23b, Mhr23b
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (mHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

PO121_HUMAN
θ value	0.0148317 (rank : 73)	NC score	0.034947 (rank : 163)
Query Neighborhood Hits	262	Target Neighborhood Hits	344	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

RHG12_HUMAN
θ value	0.0148317 (rank : 74)	NC score	0.109047 (rank : 67)
Query Neighborhood Hits	262	Target Neighborhood Hits	190	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

SETD2_HUMAN
θ value	0.0148317 (rank : 75)	NC score	0.139854 (rank : 62)
Query Neighborhood Hits	262	Target Neighborhood Hits	412	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SYTL4_MOUSE
θ value	0.0148317 (rank : 76)	NC score	0.047981 (rank : 153)
Query Neighborhood Hits	262	Target Neighborhood Hits	137	Shared Neighborhood Hits	18
SwissProt Accessions	Q9R0Q1, Q8R321, Q9R0Q0	Gene names	Sytl4, Slp4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

SYTL4_HUMAN
θ value	0.0193708 (rank : 77)	NC score	0.050452 (rank : 146)
Query Neighborhood Hits	262	Target Neighborhood Hits	138	Shared Neighborhood Hits	19
SwissProt Accessions	Q96C24, Q5H9J3, Q5JPG8, Q8N9P4, Q9H4R0, Q9H4R1	Gene names	SYTL4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

IWS1_HUMAN
θ value	0.0252991 (rank : 78)	NC score	0.037821 (rank : 160)
Query Neighborhood Hits	262	Target Neighborhood Hits	1241	Shared Neighborhood Hits	78
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MUC13_HUMAN
θ value	0.0330416 (rank : 79)	NC score	0.048843 (rank : 149)
Query Neighborhood Hits	262	Target Neighborhood Hits	164	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

SPEG_MOUSE
θ value	0.0563607 (rank : 80)	NC score	0.002239 (rank : 301)
Query Neighborhood Hits	262	Target Neighborhood Hits	1959	Shared Neighborhood Hits	80
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ZAN_MOUSE
θ value	0.0563607 (rank : 81)	NC score	0.016030 (rank : 236)
Query Neighborhood Hits	262	Target Neighborhood Hits	808	Shared Neighborhood Hits	30
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

NELFA_MOUSE
θ value	0.0736092 (rank : 82)	NC score	0.035722 (rank : 162)
Query Neighborhood Hits	262	Target Neighborhood Hits	195	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

OVGP1_HUMAN
θ value	0.0736092 (rank : 83)	NC score	0.017047 (rank : 233)
Query Neighborhood Hits	262	Target Neighborhood Hits	48	Shared Neighborhood Hits	13
SwissProt Accessions	Q12889, Q15841	Gene names	OVGP1, MUC9, OGP
Domain Architecture
Description	Oviduct-specific glycoprotein precursor (Oviductal glycoprotein) (Oviductin) (Estrogen-dependent oviduct protein) (Mucin 9).

DMD_HUMAN
θ value	0.0961366 (rank : 84)	NC score	0.051150 (rank : 142)
Query Neighborhood Hits	262	Target Neighborhood Hits	1135	Shared Neighborhood Hits	61
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

DMD_MOUSE
θ value	0.0961366 (rank : 85)	NC score	0.047283 (rank : 154)
Query Neighborhood Hits	262	Target Neighborhood Hits	1111	Shared Neighborhood Hits	61
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

DREB_MOUSE
θ value	0.0961366 (rank : 86)	NC score	0.028699 (rank : 183)
Query Neighborhood Hits	262	Target Neighborhood Hits	446	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

E2F5_HUMAN
θ value	0.0961366 (rank : 87)	NC score	0.020942 (rank : 211)
Query Neighborhood Hits	262	Target Neighborhood Hits	55	Shared Neighborhood Hits	8
SwissProt Accessions	Q15329, Q16601, Q92756	Gene names	E2F5
Domain Architecture
Description	Transcription factor E2F5 (E2F-5).

LIMA1_MOUSE
θ value	0.125558 (rank : 88)	NC score	0.020516 (rank : 214)
Query Neighborhood Hits	262	Target Neighborhood Hits	298	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ERG0, Q9ERG1	Gene names	Lima1, D15Ertd366e, Eplin
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm) (mEPLIN).

RFIP1_MOUSE
θ value	0.125558 (rank : 89)	NC score	0.031268 (rank : 172)
Query Neighborhood Hits	262	Target Neighborhood Hits	152	Shared Neighborhood Hits	16
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

SYNJ1_HUMAN
θ value	0.125558 (rank : 90)	NC score	0.022273 (rank : 207)
Query Neighborhood Hits	262	Target Neighborhood Hits	498	Shared Neighborhood Hits	47
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

APBB3_HUMAN
θ value	0.163984 (rank : 91)	NC score	0.133918 (rank : 63)
Query Neighborhood Hits	262	Target Neighborhood Hits	36	Shared Neighborhood Hits	27
SwissProt Accessions	O95704, Q9NYX6, Q9NYX7, Q9NYX8	Gene names	APBB3, FE65L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 3 (Fe65-like protein 2) (Fe65L2).

CTTB2_HUMAN
θ value	0.163984 (rank : 92)	NC score	0.010877 (rank : 257)
Query Neighborhood Hits	262	Target Neighborhood Hits	1061	Shared Neighborhood Hits	40
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

DCR1C_MOUSE
θ value	0.163984 (rank : 93)	NC score	0.020578 (rank : 213)
Query Neighborhood Hits	262	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K4J0, Q8BG72, Q8BTT1	Gene names	Dclre1c, Art, Snm1l
Domain Architecture	No domain graphic available
Description	Artemis protein (EC 3.1.-.-) (DNA cross-link repair 1C protein) (mArt protein) (SNM1-like protein).

RD23B_HUMAN
θ value	0.163984 (rank : 94)	NC score	0.033002 (rank : 166)
Query Neighborhood Hits	262	Target Neighborhood Hits	115	Shared Neighborhood Hits	14
SwissProt Accessions	P54727, Q8WUB0	Gene names	RAD23B
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (hHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

APBB3_MOUSE
θ value	0.21417 (rank : 95)	NC score	0.132986 (rank : 64)
Query Neighborhood Hits	262	Target Neighborhood Hits	32	Shared Neighborhood Hits	26
SwissProt Accessions	Q8R1C9	Gene names	Apbb3
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 3.

DGCR8_HUMAN
θ value	0.21417 (rank : 96)	NC score	0.087184 (rank : 75)
Query Neighborhood Hits	262	Target Neighborhood Hits	72	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WYQ5, Q6DCB2, Q6MZE9, Q6Y2L0, Q96G39, Q96GP8, Q9H6L8, Q9H6T7, Q9NRW2	Gene names	DGCR8, C22orf12, DGCRK6
Domain Architecture
Description	DGCR8 protein (DiGeorge syndrome critical region 8).

DGCR8_MOUSE
θ value	0.21417 (rank : 97)	NC score	0.085482 (rank : 77)
Query Neighborhood Hits	262	Target Neighborhood Hits	70	Shared Neighborhood Hits	16
SwissProt Accessions	Q9EQM6	Gene names	Dgcr8
Domain Architecture	No domain graphic available
Description	DGCR8 protein (DiGeorge syndrome critical region 8 homolog) (Gy1).

NACAM_MOUSE
θ value	0.21417 (rank : 98)	NC score	0.059344 (rank : 117)
Query Neighborhood Hits	262	Target Neighborhood Hits	1866	Shared Neighborhood Hits	136
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PAPOA_MOUSE
θ value	0.21417 (rank : 99)	NC score	0.027969 (rank : 185)
Query Neighborhood Hits	262	Target Neighborhood Hits	115	Shared Neighborhood Hits	22
SwissProt Accessions	Q61183, Q61208, Q61209, Q8K4X2	Gene names	Papola, Pap, Plap
Domain Architecture
Description	Poly(A) polymerase alpha (EC 2.7.7.19) (PAP) (Polynucleotide adenylyltransferase).

UTRO_HUMAN
θ value	0.21417 (rank : 100)	NC score	0.042849 (rank : 158)
Query Neighborhood Hits	262	Target Neighborhood Hits	960	Shared Neighborhood Hits	51
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

APBB1_HUMAN
θ value	0.279714 (rank : 101)	NC score	0.096631 (rank : 69)
Query Neighborhood Hits	262	Target Neighborhood Hits	62	Shared Neighborhood Hits	25
SwissProt Accessions	O00213, Q96A93	Gene names	APBB1, FE65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

FEZ1_HUMAN
θ value	0.279714 (rank : 102)	NC score	0.019685 (rank : 219)
Query Neighborhood Hits	262	Target Neighborhood Hits	120	Shared Neighborhood Hits	7
SwissProt Accessions	Q99689, O00679, O00728, Q6IBI7	Gene names	FEZ1
Domain Architecture	No domain graphic available
Description	Fasciculation and elongation protein zeta 1 (Zygin-1) (Zygin I).

MUC2_HUMAN
θ value	0.279714 (rank : 103)	NC score	0.032174 (rank : 167)
Query Neighborhood Hits	262	Target Neighborhood Hits	906	Shared Neighborhood Hits	61
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

PGCB_HUMAN
θ value	0.279714 (rank : 104)	NC score	0.012253 (rank : 247)
Query Neighborhood Hits	262	Target Neighborhood Hits	478	Shared Neighborhood Hits	26
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

RIMS2_HUMAN
θ value	0.279714 (rank : 105)	NC score	0.080769 (rank : 85)
Query Neighborhood Hits	262	Target Neighborhood Hits	342	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
θ value	0.279714 (rank : 106)	NC score	0.080637 (rank : 86)
Query Neighborhood Hits	262	Target Neighborhood Hits	376	Shared Neighborhood Hits	41
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

BAT2_HUMAN
θ value	0.365318 (rank : 107)	NC score	0.026974 (rank : 188)
Query Neighborhood Hits	262	Target Neighborhood Hits	931	Shared Neighborhood Hits	64
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

DRP2_HUMAN
θ value	0.365318 (rank : 108)	NC score	0.096578 (rank : 70)
Query Neighborhood Hits	262	Target Neighborhood Hits	186	Shared Neighborhood Hits	29
SwissProt Accessions	Q13474	Gene names	DRP2
Domain Architecture
Description	Dystrophin-related protein 2.

K0226_HUMAN
θ value	0.365318 (rank : 109)	NC score	0.019588 (rank : 221)
Query Neighborhood Hits	262	Target Neighborhood Hits	92	Shared Neighborhood Hits	11
SwissProt Accessions	Q92622	Gene names	KIAA0226
Domain Architecture	No domain graphic available
Description	Protein KIAA0226.

REST_HUMAN
θ value	0.365318 (rank : 110)	NC score	0.006299 (rank : 281)
Query Neighborhood Hits	262	Target Neighborhood Hits	1605	Shared Neighborhood Hits	49
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

RFIP1_HUMAN
θ value	0.365318 (rank : 111)	NC score	0.030348 (rank : 176)
Query Neighborhood Hits	262	Target Neighborhood Hits	236	Shared Neighborhood Hits	33
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

SRRM2_HUMAN
θ value	0.365318 (rank : 112)	NC score	0.048833 (rank : 150)
Query Neighborhood Hits	262	Target Neighborhood Hits	1296	Shared Neighborhood Hits	95
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

CK024_MOUSE
θ value	0.47712 (rank : 113)	NC score	0.071354 (rank : 98)
Query Neighborhood Hits	262	Target Neighborhood Hits	307	Shared Neighborhood Hits	66
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

DMP1_HUMAN
θ value	0.47712 (rank : 114)	NC score	0.031677 (rank : 169)
Query Neighborhood Hits	262	Target Neighborhood Hits	491	Shared Neighborhood Hits	26
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

GR65_MOUSE
θ value	0.47712 (rank : 115)	NC score	0.015833 (rank : 238)
Query Neighborhood Hits	262	Target Neighborhood Hits	54	Shared Neighborhood Hits	4
SwissProt Accessions	Q91X51, Q9D3L9	Gene names	Gorasp1
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 1 (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) (Golgi peripheral membrane protein p65).

HXA3_MOUSE
θ value	0.47712 (rank : 116)	NC score	0.003372 (rank : 297)
Query Neighborhood Hits	262	Target Neighborhood Hits	558	Shared Neighborhood Hits	26
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

MUC5B_HUMAN
θ value	0.47712 (rank : 117)	NC score	0.030134 (rank : 177)
Query Neighborhood Hits	262	Target Neighborhood Hits	1020	Shared Neighborhood Hits	71
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

MUC7_HUMAN
θ value	0.47712 (rank : 118)	NC score	0.043404 (rank : 157)
Query Neighborhood Hits	262	Target Neighborhood Hits	538	Shared Neighborhood Hits	64
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

ABL1_MOUSE
θ value	0.62314 (rank : 119)	NC score	-0.002034 (rank : 311)
Query Neighborhood Hits	262	Target Neighborhood Hits	1178	Shared Neighborhood Hits	34
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

AF10_HUMAN
θ value	0.62314 (rank : 120)	NC score	0.009437 (rank : 263)
Query Neighborhood Hits	262	Target Neighborhood Hits	198	Shared Neighborhood Hits	12
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

CNOT3_MOUSE
θ value	0.62314 (rank : 121)	NC score	0.021673 (rank : 209)
Query Neighborhood Hits	262	Target Neighborhood Hits	504	Shared Neighborhood Hits	37
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

DSPP_MOUSE
θ value	0.62314 (rank : 122)	NC score	0.022612 (rank : 206)
Query Neighborhood Hits	262	Target Neighborhood Hits	491	Shared Neighborhood Hits	35
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

GPR64_HUMAN
θ value	0.62314 (rank : 123)	NC score	0.006941 (rank : 279)
Query Neighborhood Hits	262	Target Neighborhood Hits	207	Shared Neighborhood Hits	16
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

IF4G3_HUMAN
θ value	0.62314 (rank : 124)	NC score	0.011741 (rank : 252)
Query Neighborhood Hits	262	Target Neighborhood Hits	247	Shared Neighborhood Hits	13
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

K0460_MOUSE
θ value	0.62314 (rank : 125)	NC score	0.026267 (rank : 192)
Query Neighborhood Hits	262	Target Neighborhood Hits	374	Shared Neighborhood Hits	40
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

NCOR2_HUMAN
θ value	0.62314 (rank : 126)	NC score	0.029770 (rank : 178)
Query Neighborhood Hits	262	Target Neighborhood Hits	870	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

PCLO_MOUSE
θ value	0.62314 (rank : 127)	NC score	0.076169 (rank : 91)
Query Neighborhood Hits	262	Target Neighborhood Hits	2275	Shared Neighborhood Hits	139
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PLXB1_HUMAN
θ value	0.62314 (rank : 128)	NC score	0.008603 (rank : 266)
Query Neighborhood Hits	262	Target Neighborhood Hits	360	Shared Neighborhood Hits	37
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

RAE1_HUMAN
θ value	0.62314 (rank : 129)	NC score	0.011779 (rank : 251)
Query Neighborhood Hits	262	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	P24386, O43732	Gene names	CHM, REP1, TCD
Domain Architecture
Description	Rab proteins geranylgeranyltransferase component A 1 (Rab escort protein 1) (REP-1) (Choroideraemia protein) (TCD protein).

TARA_HUMAN
θ value	0.62314 (rank : 130)	NC score	0.055803 (rank : 128)
Query Neighborhood Hits	262	Target Neighborhood Hits	1626	Shared Neighborhood Hits	122
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

ACINU_HUMAN
θ value	0.813845 (rank : 131)	NC score	0.025638 (rank : 193)
Query Neighborhood Hits	262	Target Neighborhood Hits	828	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ATS12_MOUSE
θ value	0.813845 (rank : 132)	NC score	0.002315 (rank : 300)
Query Neighborhood Hits	262	Target Neighborhood Hits	220	Shared Neighborhood Hits	3
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

BPTF_HUMAN
θ value	0.813845 (rank : 133)	NC score	0.023215 (rank : 202)
Query Neighborhood Hits	262	Target Neighborhood Hits	786	Shared Neighborhood Hits	55
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

FA62A_MOUSE
θ value	0.813845 (rank : 134)	NC score	0.105711 (rank : 68)
Query Neighborhood Hits	262	Target Neighborhood Hits	155	Shared Neighborhood Hits	24
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

NUP62_HUMAN
θ value	0.813845 (rank : 135)	NC score	0.018467 (rank : 224)
Query Neighborhood Hits	262	Target Neighborhood Hits	195	Shared Neighborhood Hits	14
SwissProt Accessions	P37198, Q503A4, Q96C43, Q9NSL1	Gene names	NUP62
Domain Architecture
Description	Nuclear pore glycoprotein p62 (62 kDa nucleoporin).

XE7_HUMAN
θ value	0.813845 (rank : 136)	NC score	0.011703 (rank : 253)
Query Neighborhood Hits	262	Target Neighborhood Hits	738	Shared Neighborhood Hits	26
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

BMX_HUMAN
θ value	1.06291 (rank : 137)	NC score	0.001202 (rank : 303)
Query Neighborhood Hits	262	Target Neighborhood Hits	942	Shared Neighborhood Hits	17
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

CAF1A_HUMAN
θ value	1.06291 (rank : 138)	NC score	0.015505 (rank : 241)
Query Neighborhood Hits	262	Target Neighborhood Hits	750	Shared Neighborhood Hits	30
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

DYNA_HUMAN
θ value	1.06291 (rank : 139)	NC score	0.007471 (rank : 276)
Query Neighborhood Hits	262	Target Neighborhood Hits	1194	Shared Neighborhood Hits	37
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

ENL_HUMAN
θ value	1.06291 (rank : 140)	NC score	0.025340 (rank : 195)
Query Neighborhood Hits	262	Target Neighborhood Hits	305	Shared Neighborhood Hits	31
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

K1958_HUMAN
θ value	1.06291 (rank : 141)	NC score	0.020241 (rank : 215)
Query Neighborhood Hits	262	Target Neighborhood Hits	76	Shared Neighborhood Hits	16
SwissProt Accessions	Q8N8K9, Q5T252, Q8TF43, Q96N02	Gene names	KIAA1958
Domain Architecture	No domain graphic available
Description	Protein KIAA1958.

MLH3_HUMAN
θ value	1.06291 (rank : 142)	NC score	0.024995 (rank : 196)
Query Neighborhood Hits	262	Target Neighborhood Hits	42	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UHC1, P49751, Q56DK9, Q9P292, Q9UHC0	Gene names	MLH3
Domain Architecture
Description	DNA mismatch repair protein Mlh3 (MutL protein homolog 3).

SDC3_HUMAN
θ value	1.06291 (rank : 143)	NC score	0.021665 (rank : 210)
Query Neighborhood Hits	262	Target Neighborhood Hits	103	Shared Neighborhood Hits	22
SwissProt Accessions	O75056, Q5T1Z6, Q5T1Z7, Q96CT3, Q96PR8	Gene names	SDC3, KIAA0468
Domain Architecture
Description	Syndecan-3 (SYND3).

T240L_HUMAN
θ value	1.06291 (rank : 144)	NC score	0.017208 (rank : 231)
Query Neighborhood Hits	262	Target Neighborhood Hits	132	Shared Neighborhood Hits	16
SwissProt Accessions	Q71F56, Q68DN4, Q9H8C0, Q9NSY9, Q9UFD8, Q9UPX5	Gene names	THRAP2, KIAA1025, PROSIT240, TRAP240L
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

AKAP2_HUMAN
θ value	1.38821 (rank : 145)	NC score	0.019918 (rank : 217)
Query Neighborhood Hits	262	Target Neighborhood Hits	507	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

APBB1_MOUSE
θ value	1.38821 (rank : 146)	NC score	0.095973 (rank : 71)
Query Neighborhood Hits	262	Target Neighborhood Hits	75	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QXJ1, O08642, Q3TPU0, Q8BNF4, Q8BSR9	Gene names	Apbb1, Fe65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

CFAH_MOUSE
θ value	1.38821 (rank : 147)	NC score	0.005901 (rank : 283)
Query Neighborhood Hits	262	Target Neighborhood Hits	112	Shared Neighborhood Hits	6
SwissProt Accessions	P06909	Gene names	Cfh, Hf1
Domain Architecture
Description	Complement factor H precursor (Protein beta-1-H).

HIPK3_HUMAN
θ value	1.38821 (rank : 148)	NC score	-0.002246 (rank : 312)
Query Neighborhood Hits	262	Target Neighborhood Hits	867	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H422, O14632, Q2PBG4, Q2PBG5, Q92632, Q9HAS2	Gene names	HIPK3, DYRK6, FIST3, PKY
Domain Architecture	No domain graphic available
Description	Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Homolog of protein kinase YAK1) (Fas-interacting serine/threonine-protein kinase) (FIST) (Androgen receptor-interacting nuclear protein kinase) (ANPK).

NCA11_MOUSE
θ value	1.38821 (rank : 149)	NC score	0.004772 (rank : 291)
Query Neighborhood Hits	262	Target Neighborhood Hits	661	Shared Neighborhood Hits	36
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

PODXL_HUMAN
θ value	1.38821 (rank : 150)	NC score	0.043588 (rank : 156)
Query Neighborhood Hits	262	Target Neighborhood Hits	191	Shared Neighborhood Hits	38
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

ATN1_HUMAN
θ value	1.81305 (rank : 151)	NC score	0.023279 (rank : 201)
Query Neighborhood Hits	262	Target Neighborhood Hits	676	Shared Neighborhood Hits	56
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

DLG7_HUMAN
θ value	1.81305 (rank : 152)	NC score	0.023907 (rank : 199)
Query Neighborhood Hits	262	Target Neighborhood Hits	53	Shared Neighborhood Hits	7
SwissProt Accessions	Q15398, Q8NG58	Gene names	DLG7, KIAA0008
Domain Architecture
Description	Discs large homolog 7 (Hepatoma up-regulated protein) (HURP).

DLG7_MOUSE
θ value	1.81305 (rank : 153)	NC score	0.022647 (rank : 205)
Query Neighborhood Hits	262	Target Neighborhood Hits	84	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K4R9, Q6ZQL3, Q80VS7, Q8BUC8, Q8BZ79	Gene names	Dlg7, Kiaa0008
Domain Architecture	No domain graphic available
Description	Discs large homolog 7 (Hepatoma up-regulated protein homolog) (HURP).

MILK1_MOUSE
θ value	1.81305 (rank : 154)	NC score	0.023033 (rank : 203)
Query Neighborhood Hits	262	Target Neighborhood Hits	788	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

PCLO_HUMAN
θ value	1.81305 (rank : 155)	NC score	0.075678 (rank : 94)
Query Neighborhood Hits	262	Target Neighborhood Hits	2046	Shared Neighborhood Hits	143
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PF21B_MOUSE
θ value	1.81305 (rank : 156)	NC score	0.019656 (rank : 220)
Query Neighborhood Hits	262	Target Neighborhood Hits	278	Shared Neighborhood Hits	42
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

SELPL_MOUSE
θ value	1.81305 (rank : 157)	NC score	0.048703 (rank : 151)
Query Neighborhood Hits	262	Target Neighborhood Hits	588	Shared Neighborhood Hits	82
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SOX30_HUMAN
θ value	1.81305 (rank : 158)	NC score	0.010621 (rank : 259)
Query Neighborhood Hits	262	Target Neighborhood Hits	305	Shared Neighborhood Hits	33
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

SP4_MOUSE
θ value	1.81305 (rank : 159)	NC score	-0.004991 (rank : 316)
Query Neighborhood Hits	262	Target Neighborhood Hits	759	Shared Neighborhood Hits	12
SwissProt Accessions	Q62445	Gene names	Sp4
Domain Architecture
Description	Transcription factor Sp4.

STON2_MOUSE
θ value	1.81305 (rank : 160)	NC score	0.012114 (rank : 249)
Query Neighborhood Hits	262	Target Neighborhood Hits	75	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BZ60	Gene names	Ston2, Stn2, Stnb
Domain Architecture
Description	Stonin-2 (Stoned B).

TCOF_HUMAN
θ value	1.81305 (rank : 161)	NC score	0.029007 (rank : 181)
Query Neighborhood Hits	262	Target Neighborhood Hits	543	Shared Neighborhood Hits	48
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

AKAP6_HUMAN
θ value	2.36792 (rank : 162)	NC score	0.016664 (rank : 234)
Query Neighborhood Hits	262	Target Neighborhood Hits	263	Shared Neighborhood Hits	22
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

AP3B1_HUMAN
θ value	2.36792 (rank : 163)	NC score	0.008950 (rank : 264)
Query Neighborhood Hits	262	Target Neighborhood Hits	283	Shared Neighborhood Hits	19
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

CAC1A_MOUSE
θ value	2.36792 (rank : 164)	NC score	0.012218 (rank : 248)
Query Neighborhood Hits	262	Target Neighborhood Hits	267	Shared Neighborhood Hits	27
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CBP_HUMAN
θ value	2.36792 (rank : 165)	NC score	0.029686 (rank : 180)
Query Neighborhood Hits	262	Target Neighborhood Hits	941	Shared Neighborhood Hits	73
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CBP_MOUSE
θ value	2.36792 (rank : 166)	NC score	0.029744 (rank : 179)
Query Neighborhood Hits	262	Target Neighborhood Hits	1051	Shared Neighborhood Hits	85
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CE025_HUMAN
θ value	2.36792 (rank : 167)	NC score	0.017367 (rank : 230)
Query Neighborhood Hits	262	Target Neighborhood Hits	114	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NDZ2, Q6NXN8, Q6ZTU4, Q8IZ15	Gene names	C5orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C5orf25.

CSF1_HUMAN
θ value	2.36792 (rank : 168)	NC score	0.026793 (rank : 189)
Query Neighborhood Hits	262	Target Neighborhood Hits	258	Shared Neighborhood Hits	36
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

ITIH1_HUMAN
θ value	2.36792 (rank : 169)	NC score	0.006192 (rank : 282)
Query Neighborhood Hits	262	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	P19827, P78455, Q01746	Gene names	ITIH1, IGHEP1
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H1 precursor (ITI heavy chain H1) (Inter-alpha-inhibitor heavy chain 1) (Inter-alpha-trypsin inhibitor complex component III) (Serum-derived hyaluronan-associated protein) (SHAP).

KSR1_MOUSE
θ value	2.36792 (rank : 170)	NC score	-0.002766 (rank : 313)
Query Neighborhood Hits	262	Target Neighborhood Hits	870	Shared Neighborhood Hits	15
SwissProt Accessions	Q61097, Q61648, Q78DX8	Gene names	Ksr1, Ksr
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras) (mKSR1) (Hb protein).

NELFA_HUMAN
θ value	2.36792 (rank : 171)	NC score	0.028965 (rank : 182)
Query Neighborhood Hits	262	Target Neighborhood Hits	161	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H3P2, O95392	Gene names	WHSC2, NELFA
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 protein).

PARM1_MOUSE
θ value	2.36792 (rank : 172)	NC score	0.031745 (rank : 168)
Query Neighborhood Hits	262	Target Neighborhood Hits	140	Shared Neighborhood Hits	33
SwissProt Accessions	Q923D3, Q3TTV0, Q3UFU4	Gene names
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

SPESP_HUMAN
θ value	2.36792 (rank : 173)	NC score	0.015713 (rank : 239)
Query Neighborhood Hits	262	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q6UW49, Q8NG22, Q8WVH8	Gene names	SPESP1
Domain Architecture	No domain graphic available
Description	Sperm equatorial segment protein 1 precursor (SP-ESP) (Equatorial segment protein) (ESP) (Glycosylated 38 kDa sperm protein C-7/8).

SRRM2_MOUSE
θ value	2.36792 (rank : 174)	NC score	0.049385 (rank : 148)
Query Neighborhood Hits	262	Target Neighborhood Hits	1470	Shared Neighborhood Hits	114
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TARA_MOUSE
θ value	2.36792 (rank : 175)	NC score	0.026641 (rank : 191)
Query Neighborhood Hits	262	Target Neighborhood Hits	1133	Shared Neighborhood Hits	80
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TR240_HUMAN
θ value	2.36792 (rank : 176)	NC score	0.015607 (rank : 240)
Query Neighborhood Hits	262	Target Neighborhood Hits	99	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UHV7, O60334	Gene names	THRAP1, ARC250, KIAA0593, TRAP240
Domain Architecture
Description	Thyroid hormone receptor-associated protein complex 240 kDa component (Trap240) (Thyroid hormone receptor-associated protein 1) (Vitamin D3 receptor-interacting protein complex component DRIP250) (DRIP 250) (Activator-recruited cofactor 250 kDa component) (ARC250).

CAC1A_HUMAN
θ value	3.0926 (rank : 177)	NC score	0.007761 (rank : 272)
Query Neighborhood Hits	262	Target Neighborhood Hits	387	Shared Neighborhood Hits	29
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CHD9_MOUSE
θ value	3.0926 (rank : 178)	NC score	0.004931 (rank : 288)
Query Neighborhood Hits	262	Target Neighborhood Hits	427	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

COIA1_HUMAN
θ value	3.0926 (rank : 179)	NC score	0.005149 (rank : 287)
Query Neighborhood Hits	262	Target Neighborhood Hits	447	Shared Neighborhood Hits	25
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

DGLA_MOUSE
θ value	3.0926 (rank : 180)	NC score	0.007924 (rank : 270)
Query Neighborhood Hits	262	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	Q6WQJ1, Q6ZQ76	Gene names	Nsddr, Kiaa0659
Domain Architecture	No domain graphic available
Description	Sn1-specific diacylglycerol lipase alpha (EC 3.1.1.-) (DGL-alpha) (Neural stem cell-derived dendrite regulator).

HCFC1_HUMAN
θ value	3.0926 (rank : 181)	NC score	0.018337 (rank : 226)
Query Neighborhood Hits	262	Target Neighborhood Hits	331	Shared Neighborhood Hits	41
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

HXB5_HUMAN
θ value	3.0926 (rank : 182)	NC score	0.001743 (rank : 302)
Query Neighborhood Hits	262	Target Neighborhood Hits	332	Shared Neighborhood Hits	11
SwissProt Accessions	P09067, P09069	Gene names	HOXB5, HOX2A
Domain Architecture
Description	Homeobox protein Hox-B5 (Hox-2A) (HHO.C10) (HU-1).

IWS1_MOUSE
θ value	3.0926 (rank : 183)	NC score	0.034852 (rank : 164)
Query Neighborhood Hits	262	Target Neighborhood Hits	1258	Shared Neighborhood Hits	78
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PGCB_MOUSE
θ value	3.0926 (rank : 184)	NC score	0.007643 (rank : 274)
Query Neighborhood Hits	262	Target Neighborhood Hits	459	Shared Neighborhood Hits	16
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

PRG4_HUMAN
θ value	3.0926 (rank : 185)	NC score	0.030830 (rank : 174)
Query Neighborhood Hits	262	Target Neighborhood Hits	764	Shared Neighborhood Hits	62
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

WNK1_HUMAN
θ value	3.0926 (rank : 186)	NC score	-0.001168 (rank : 309)
Query Neighborhood Hits	262	Target Neighborhood Hits	1158	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

ADRM1_HUMAN
θ value	4.03905 (rank : 187)	NC score	0.017104 (rank : 232)
Query Neighborhood Hits	262	Target Neighborhood Hits	81	Shared Neighborhood Hits	10
SwissProt Accessions	Q16186, Q9H1P2	Gene names	ADRM1, GP110
Domain Architecture
Description	Adhesion-regulating molecule 1 precursor (110 kDa cell membrane glycoprotein) (Gp110).

ADRM1_MOUSE
θ value	4.03905 (rank : 188)	NC score	0.018714 (rank : 223)
Query Neighborhood Hits	262	Target Neighborhood Hits	84	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JKV1	Gene names	Adrm1, Gp110
Domain Architecture
Description	Adhesion-regulating molecule 1 precursor (110 kDa cell membrane glycoprotein) (Gp110) (ARM-1).

BIN1_MOUSE
θ value	4.03905 (rank : 189)	NC score	0.013174 (rank : 244)
Query Neighborhood Hits	262	Target Neighborhood Hits	283	Shared Neighborhood Hits	20
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

CN155_HUMAN
θ value	4.03905 (rank : 190)	NC score	0.031255 (rank : 173)
Query Neighborhood Hits	262	Target Neighborhood Hits	385	Shared Neighborhood Hits	40
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

CSPG2_HUMAN
θ value	4.03905 (rank : 191)	NC score	0.007679 (rank : 273)
Query Neighborhood Hits	262	Target Neighborhood Hits	681	Shared Neighborhood Hits	44
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

DSPP_HUMAN
θ value	4.03905 (rank : 192)	NC score	0.026738 (rank : 190)
Query Neighborhood Hits	262	Target Neighborhood Hits	645	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

EMAL4_HUMAN
θ value	4.03905 (rank : 193)	NC score	0.004326 (rank : 293)
Query Neighborhood Hits	262	Target Neighborhood Hits	306	Shared Neighborhood Hits	13
SwissProt Accessions	Q9HC35	Gene names	EML4, C2orf2, EMAPL4
Domain Architecture
Description	Echinoderm microtubule-associated protein-like 4 (EMAP-4) (Restrictedly overexpressed proliferation-associated protein) (Ropp 120).

FA62A_HUMAN
θ value	4.03905 (rank : 194)	NC score	0.089954 (rank : 74)
Query Neighborhood Hits	262	Target Neighborhood Hits	168	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

JIP3_HUMAN
θ value	4.03905 (rank : 195)	NC score	0.011115 (rank : 255)
Query Neighborhood Hits	262	Target Neighborhood Hits	1039	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

MTF1_HUMAN
θ value	4.03905 (rank : 196)	NC score	-0.005714 (rank : 318)
Query Neighborhood Hits	262	Target Neighborhood Hits	814	Shared Neighborhood Hits	20
SwissProt Accessions	Q14872, Q96CB1	Gene names	MTF1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

MUCDL_HUMAN
θ value	4.03905 (rank : 197)	NC score	0.017999 (rank : 228)
Query Neighborhood Hits	262	Target Neighborhood Hits	777	Shared Neighborhood Hits	56
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

PEX14_HUMAN
θ value	4.03905 (rank : 198)	NC score	0.010482 (rank : 260)
Query Neighborhood Hits	262	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	O75381, Q8WX51	Gene names	PEX14
Domain Architecture
Description	Peroxisomal membrane protein PEX14 (Peroxin-14) (Peroxisomal membrane anchor protein PEX14) (PTS1 receptor docking protein).

PRG4_MOUSE
θ value	4.03905 (rank : 199)	NC score	0.021903 (rank : 208)
Query Neighborhood Hits	262	Target Neighborhood Hits	624	Shared Neighborhood Hits	55
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

RAI1_HUMAN
θ value	4.03905 (rank : 200)	NC score	0.015846 (rank : 237)
Query Neighborhood Hits	262	Target Neighborhood Hits	360	Shared Neighborhood Hits	36
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

SETX_HUMAN
θ value	4.03905 (rank : 201)	NC score	0.012602 (rank : 246)
Query Neighborhood Hits	262	Target Neighborhood Hits	368	Shared Neighborhood Hits	29
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

SYNJ1_MOUSE
θ value	4.03905 (rank : 202)	NC score	0.023572 (rank : 200)
Query Neighborhood Hits	262	Target Neighborhood Hits	516	Shared Neighborhood Hits	57
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TARSH_HUMAN
θ value	4.03905 (rank : 203)	NC score	0.025422 (rank : 194)
Query Neighborhood Hits	262	Target Neighborhood Hits	768	Shared Neighborhood Hits	66
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TJAP1_HUMAN
θ value	4.03905 (rank : 204)	NC score	0.016090 (rank : 235)
Query Neighborhood Hits	262	Target Neighborhood Hits	214	Shared Neighborhood Hits	14
SwissProt Accessions	Q5JTD0, Q5JTD1, Q5JWW1, Q68DB2, Q6P2P3, Q9H7V7	Gene names	TJAP1, PILT, TJP4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

UBXD2_HUMAN
θ value	4.03905 (rank : 205)	NC score	0.009831 (rank : 261)
Query Neighborhood Hits	262	Target Neighborhood Hits	241	Shared Neighborhood Hits	15
SwissProt Accessions	Q92575, Q8IYM5	Gene names	UBXD2, KIAA0242, UBXDC1
Domain Architecture
Description	UBX domain-containing protein 2.

CAF1B_HUMAN
θ value	5.27518 (rank : 206)	NC score	0.000900 (rank : 305)
Query Neighborhood Hits	262	Target Neighborhood Hits	345	Shared Neighborhood Hits	12
SwissProt Accessions	Q13112, Q99548	Gene names	CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7
Domain Architecture
Description	Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60) (M- phase phosphoprotein 7).

CB017_MOUSE
θ value	5.27518 (rank : 207)	NC score	0.008404 (rank : 268)
Query Neighborhood Hits	262	Target Neighborhood Hits	63	Shared Neighborhood Hits	6
SwissProt Accessions	Q6NS82, Q3TA48, Q8BSD3, Q8CHY1, Q8R0Q3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf17 homolog.

FREA_HUMAN
θ value	5.27518 (rank : 208)	NC score	0.001049 (rank : 304)
Query Neighborhood Hits	262	Target Neighborhood Hits	205	Shared Neighborhood Hits	16
SwissProt Accessions	O43638, Q96D28	Gene names	FKHL18, FREAC10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein).

LNK_HUMAN
θ value	5.27518 (rank : 209)	NC score	0.005347 (rank : 286)
Query Neighborhood Hits	262	Target Neighborhood Hits	151	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UQQ2, O95184	Gene names	LNK
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

MINT_MOUSE
θ value	5.27518 (rank : 210)	NC score	0.019976 (rank : 216)
Query Neighborhood Hits	262	Target Neighborhood Hits	1514	Shared Neighborhood Hits	96
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MYOF_HUMAN
θ value	5.27518 (rank : 211)	NC score	0.054486 (rank : 131)
Query Neighborhood Hits	262	Target Neighborhood Hits	147	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NZM1, Q9HBU3, Q9NZM0, Q9ULL3, Q9Y4U4	Gene names	FER1L3, KIAA1207, MYOF
Domain Architecture
Description	Myoferlin (Fer-1-like protein 3).

OPHN1_MOUSE
θ value	5.27518 (rank : 212)	NC score	0.010665 (rank : 258)
Query Neighborhood Hits	262	Target Neighborhood Hits	174	Shared Neighborhood Hits	7
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

PEG3_MOUSE
θ value	5.27518 (rank : 213)	NC score	-0.000080 (rank : 307)
Query Neighborhood Hits	262	Target Neighborhood Hits	1101	Shared Neighborhood Hits	32
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

PI5PA_MOUSE
θ value	5.27518 (rank : 214)	NC score	0.013993 (rank : 243)
Query Neighborhood Hits	262	Target Neighborhood Hits	331	Shared Neighborhood Hits	31
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PLK4_MOUSE
θ value	5.27518 (rank : 215)	NC score	-0.005112 (rank : 317)
Query Neighborhood Hits	262	Target Neighborhood Hits	879	Shared Neighborhood Hits	15
SwissProt Accessions	Q64702, Q6PEP6, Q78EG6, Q8R0I5, Q9CVR6, Q9CVU6	Gene names	Plk4, Sak, Stk18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine- protein kinase 18).

PYGO2_HUMAN
θ value	5.27518 (rank : 216)	NC score	0.011920 (rank : 250)
Query Neighborhood Hits	262	Target Neighborhood Hits	189	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

SRRM1_HUMAN
θ value	5.27518 (rank : 217)	NC score	0.031447 (rank : 170)
Query Neighborhood Hits	262	Target Neighborhood Hits	690	Shared Neighborhood Hits	47
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SUSD4_MOUSE
θ value	5.27518 (rank : 218)	NC score	0.005700 (rank : 285)
Query Neighborhood Hits	262	Target Neighborhood Hits	122	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BH32, Q8VC43	Gene names	Susd4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

SYTL2_MOUSE
θ value	5.27518 (rank : 219)	NC score	0.053967 (rank : 133)
Query Neighborhood Hits	262	Target Neighborhood Hits	253	Shared Neighborhood Hits	29
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

UBP28_MOUSE
θ value	5.27518 (rank : 220)	NC score	0.004813 (rank : 290)
Query Neighborhood Hits	262	Target Neighborhood Hits	178	Shared Neighborhood Hits	12
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

ZCH10_MOUSE
θ value	5.27518 (rank : 221)	NC score	0.018351 (rank : 225)
Query Neighborhood Hits	262	Target Neighborhood Hits	133	Shared Neighborhood Hits	13
SwissProt Accessions	Q9CX48	Gene names	Zcchc10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

ABL1_HUMAN
θ value	6.88961 (rank : 222)	NC score	-0.003869 (rank : 315)
Query Neighborhood Hits	262	Target Neighborhood Hits	1220	Shared Neighborhood Hits	30
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ACM4_HUMAN
θ value	6.88961 (rank : 223)	NC score	-0.006045 (rank : 319)
Query Neighborhood Hits	262	Target Neighborhood Hits	889	Shared Neighborhood Hits	4
SwissProt Accessions	P08173	Gene names	CHRM4
Domain Architecture
Description	Muscarinic acetylcholine receptor M4.

CAC1B_HUMAN
θ value	6.88961 (rank : 224)	NC score	0.007361 (rank : 277)
Query Neighborhood Hits	262	Target Neighborhood Hits	257	Shared Neighborhood Hits	19
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CK024_HUMAN
θ value	6.88961 (rank : 225)	NC score	0.030393 (rank : 175)
Query Neighborhood Hits	262	Target Neighborhood Hits	408	Shared Neighborhood Hits	61
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

DYNA_MOUSE
θ value	6.88961 (rank : 226)	NC score	0.005701 (rank : 284)
Query Neighborhood Hits	262	Target Neighborhood Hits	1084	Shared Neighborhood Hits	33
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

E2F5_MOUSE
θ value	6.88961 (rank : 227)	NC score	0.013165 (rank : 245)
Query Neighborhood Hits	262	Target Neighborhood Hits	43	Shared Neighborhood Hits	6
SwissProt Accessions	Q61502	Gene names	E2f5
Domain Architecture
Description	Transcription factor E2F5 (E2F-5).

EDAD_MOUSE
θ value	6.88961 (rank : 228)	NC score	0.008093 (rank : 269)
Query Neighborhood Hits	262	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VHX2	Gene names	Edaradd, Cr
Domain Architecture	No domain graphic available
Description	Ectodysplasin A receptor-associated adapter protein (EDAR-associated death domain protein) (Crinkled protein).

GP112_HUMAN
θ value	6.88961 (rank : 229)	NC score	0.024053 (rank : 198)
Query Neighborhood Hits	262	Target Neighborhood Hits	441	Shared Neighborhood Hits	57
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

HXB5_MOUSE
θ value	6.88961 (rank : 230)	NC score	0.002865 (rank : 298)
Query Neighborhood Hits	262	Target Neighborhood Hits	337	Shared Neighborhood Hits	13
SwissProt Accessions	P09079, Q3ZAY8	Gene names	Hoxb5, Hox-2.1, Hoxb-5
Domain Architecture
Description	Homeobox protein Hox-B5 (Hox-2.1) (MU-1) (H24.1).

MINT_HUMAN
θ value	6.88961 (rank : 231)	NC score	0.020754 (rank : 212)
Query Neighborhood Hits	262	Target Neighborhood Hits	1291	Shared Neighborhood Hits	95
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NFAT5_HUMAN
θ value	6.88961 (rank : 232)	NC score	0.004353 (rank : 292)
Query Neighborhood Hits	262	Target Neighborhood Hits	217	Shared Neighborhood Hits	12
SwissProt Accessions	O94916, O95693, Q9UN18	Gene names	NFAT5, KIAA0827, TONEBP
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T-cell transcription factor NFAT5) (NF-AT5) (Tonicity-responsive enhancer-binding protein) (TonE- binding protein) (TonEBP).

NU214_HUMAN
θ value	6.88961 (rank : 233)	NC score	0.048577 (rank : 152)
Query Neighborhood Hits	262	Target Neighborhood Hits	657	Shared Neighborhood Hits	71
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

RTN1_HUMAN
θ value	6.88961 (rank : 234)	NC score	0.008467 (rank : 267)
Query Neighborhood Hits	262	Target Neighborhood Hits	173	Shared Neighborhood Hits	16
SwissProt Accessions	Q16799, Q16800, Q16801	Gene names	RTN1, NSP
Domain Architecture
Description	Reticulon-1 (Neuroendocrine-specific protein).

SET1A_HUMAN
θ value	6.88961 (rank : 235)	NC score	0.028629 (rank : 184)
Query Neighborhood Hits	262	Target Neighborhood Hits	690	Shared Neighborhood Hits	59
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SRRM1_MOUSE
θ value	6.88961 (rank : 236)	NC score	0.031334 (rank : 171)
Query Neighborhood Hits	262	Target Neighborhood Hits	966	Shared Neighborhood Hits	67
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TACC2_MOUSE
θ value	6.88961 (rank : 237)	NC score	0.007571 (rank : 275)
Query Neighborhood Hits	262	Target Neighborhood Hits	774	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

TJAP1_MOUSE
θ value	6.88961 (rank : 238)	NC score	0.009737 (rank : 262)
Query Neighborhood Hits	262	Target Neighborhood Hits	295	Shared Neighborhood Hits	15
SwissProt Accessions	Q9DCD5, Q8CFL7, Q8R5I2	Gene names	Tjap1, Pilt, Tjp4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

TRBP2_MOUSE
θ value	6.88961 (rank : 239)	NC score	0.007085 (rank : 278)
Query Neighborhood Hits	262	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	P97473	Gene names	Tarbp2, Prbp
Domain Architecture
Description	TAR RNA-binding protein 2 (Protamine-1 RNA-binding protein) (PRM-1 RNA-binding protein).

WBP4_MOUSE
θ value	6.88961 (rank : 240)	NC score	0.114104 (rank : 66)
Query Neighborhood Hits	262	Target Neighborhood Hits	100	Shared Neighborhood Hits	36
SwissProt Accessions	Q61048, Q8K1Z9, Q9CS45	Gene names	Wbp4, Fbp21, Fnbp21
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21).

CHD4_MOUSE
θ value	8.99809 (rank : 241)	NC score	0.004240 (rank : 295)
Query Neighborhood Hits	262	Target Neighborhood Hits	408	Shared Neighborhood Hits	25
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

DIDO1_HUMAN
θ value	8.99809 (rank : 242)	NC score	0.011205 (rank : 254)
Query Neighborhood Hits	262	Target Neighborhood Hits	960	Shared Neighborhood Hits	58
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

E2AK3_HUMAN
θ value	8.99809 (rank : 243)	NC score	-0.000371 (rank : 308)
Query Neighborhood Hits	262	Target Neighborhood Hits	859	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NZJ5, O95846	Gene names	EIF2AK3, PEK, PERK
Domain Architecture
Description	Eukaryotic translation initiation factor 2-alpha kinase 3 precursor (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) (HsPEK).

E2F4_HUMAN
θ value	8.99809 (rank : 244)	NC score	0.024636 (rank : 197)
Query Neighborhood Hits	262	Target Neighborhood Hits	188	Shared Neighborhood Hits	27
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).

GASP1_MOUSE
θ value	8.99809 (rank : 245)	NC score	0.004148 (rank : 296)
Query Neighborhood Hits	262	Target Neighborhood Hits	169	Shared Neighborhood Hits	15
SwissProt Accessions	Q5U4C1, Q8BKR8, Q8BUN4, Q8BYK9, Q8CHF4, Q8R095	Gene names	Gprasp1, Kiaa0443
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 1 (GASP-1).

GSCR1_HUMAN
θ value	8.99809 (rank : 246)	NC score	0.015027 (rank : 242)
Query Neighborhood Hits	262	Target Neighborhood Hits	674	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

HA26_HUMAN
θ value	8.99809 (rank : 247)	NC score	0.000013 (rank : 306)
Query Neighborhood Hits	262	Target Neighborhood Hits	200	Shared Neighborhood Hits	3
SwissProt Accessions	P01906, O19789	Gene names	HLA-DQA2
Domain Architecture
Description	HLA class II histocompatibility antigen, DQ(6) alpha chain precursor (DX alpha chain) (HLA-DQA1).

IRF2_HUMAN
θ value	8.99809 (rank : 248)	NC score	0.002735 (rank : 299)
Query Neighborhood Hits	262	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	P14316, Q96B99	Gene names	IRF2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).

MDC1_MOUSE
θ value	8.99809 (rank : 249)	NC score	0.037366 (rank : 161)
Query Neighborhood Hits	262	Target Neighborhood Hits	998	Shared Neighborhood Hits	105
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MILK1_HUMAN
θ value	8.99809 (rank : 250)	NC score	0.019716 (rank : 218)
Query Neighborhood Hits	262	Target Neighborhood Hits	427	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MLL3_HUMAN
θ value	8.99809 (rank : 251)	NC score	0.018170 (rank : 227)
Query Neighborhood Hits	262	Target Neighborhood Hits	1644	Shared Neighborhood Hits	100
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

NKX28_MOUSE
θ value	8.99809 (rank : 252)	NC score	-0.001686 (rank : 310)
Query Neighborhood Hits	262	Target Neighborhood Hits	347	Shared Neighborhood Hits	5
SwissProt Accessions	O70584	Gene names	Nkx2-8, Nkx-2.9, Nkx2-9, Nkx2h
Domain Architecture
Description	Homeobox protein Nkx-2.8 (Homeobox protein NK-2 homolog H) (Homeobox protein Nkx-2.9).

NP1L3_MOUSE
θ value	8.99809 (rank : 253)	NC score	0.004815 (rank : 289)
Query Neighborhood Hits	262	Target Neighborhood Hits	233	Shared Neighborhood Hits	15
SwissProt Accessions	Q794H2, O54802	Gene names	Nap1l3, Mb20
Domain Architecture	No domain graphic available
Description	Nucleosome assembly protein 1-like 3 (Brain-specific protein MB20).

ORC3_HUMAN
θ value	8.99809 (rank : 254)	NC score	0.007882 (rank : 271)
Query Neighborhood Hits	262	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UBD5, Q13565, Q6IUY7, Q9UG44, Q9UNT6	Gene names	ORC3L, LATHEO
Domain Architecture
Description	Origin recognition complex subunit 3 (Origin recognition complex subunit Latheo).

PYGO1_HUMAN
θ value	8.99809 (rank : 255)	NC score	0.008921 (rank : 265)
Query Neighborhood Hits	262	Target Neighborhood Hits	90	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y3Y4	Gene names	PYGO1
Domain Architecture
Description	Pygopus homolog 1.

SCN7A_HUMAN
θ value	8.99809 (rank : 256)	NC score	0.004304 (rank : 294)
Query Neighborhood Hits	262	Target Neighborhood Hits	135	Shared Neighborhood Hits	9
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

STK10_HUMAN
θ value	8.99809 (rank : 257)	NC score	-0.003246 (rank : 314)
Query Neighborhood Hits	262	Target Neighborhood Hits	1921	Shared Neighborhood Hits	62
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

TM108_MOUSE
θ value	8.99809 (rank : 258)	NC score	0.017402 (rank : 229)
Query Neighborhood Hits	262	Target Neighborhood Hits	336	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

TP53B_HUMAN
θ value	8.99809 (rank : 259)	NC score	0.027234 (rank : 187)
Query Neighborhood Hits	262	Target Neighborhood Hits	413	Shared Neighborhood Hits	40
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TRBP2_HUMAN
θ value	8.99809 (rank : 260)	NC score	0.006458 (rank : 280)
Query Neighborhood Hits	262	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q15633, Q12878	Gene names	TARBP2, TRBP
Domain Architecture
Description	TAR RNA-binding protein 2 (Trans-activation-responsive RNA-binding protein).

YETS2_HUMAN
θ value	8.99809 (rank : 261)	NC score	0.011091 (rank : 256)
Query Neighborhood Hits	262	Target Neighborhood Hits	212	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ULM3, Q641P6, Q9NW96	Gene names	YEATS2, KIAA1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

ZN406_MOUSE
θ value	8.99809 (rank : 262)	NC score	-0.006381 (rank : 320)
Query Neighborhood Hits	262	Target Neighborhood Hits	800	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TS63	Gene names	Znf406, Zfp406
Domain Architecture	No domain graphic available
Description	Zinc finger protein 406.

ALS2_HUMAN
θ value	θ > 10 (rank : 263)	NC score	0.052370 (rank : 137)
Query Neighborhood Hits	262	Target Neighborhood Hits	121	Shared Neighborhood Hits	9
SwissProt Accessions	Q96Q42, Q8N1E0, Q96PC4, Q96Q41, Q9H973, Q9HCK9	Gene names	ALS2, KIAA1563
Domain Architecture
Description	Alsin (Amyotrophic lateral sclerosis protein 2).

ALS2_MOUSE
θ value	θ > 10 (rank : 264)	NC score	0.050586 (rank : 145)
Query Neighborhood Hits	262	Target Neighborhood Hits	111	Shared Neighborhood Hits	8
SwissProt Accessions	Q920R0, Q8JZR1, Q9CXJ3	Gene names	Als2
Domain Architecture
Description	Alsin (Amyotrophic lateral sclerosis protein 2 homolog).

BAIP3_MOUSE
θ value	θ > 10 (rank : 265)	NC score	0.050323 (rank : 147)
Query Neighborhood Hits	262	Target Neighborhood Hits	112	Shared Neighborhood Hits	18
SwissProt Accessions	Q80TT2, Q6RUT4	Gene names	Baiap3, Gm937, Kiaa0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

CUL7_HUMAN
θ value	θ > 10 (rank : 266)	NC score	0.055957 (rank : 127)
Query Neighborhood Hits	262	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	Q14999, Q5T654	Gene names	CUL7, KIAA0076
Domain Architecture
Description	Cullin-7 (CUL-7).

DOC2A_HUMAN
θ value	θ > 10 (rank : 267)	NC score	0.070189 (rank : 101)
Query Neighborhood Hits	262	Target Neighborhood Hits	144	Shared Neighborhood Hits	18
SwissProt Accessions	Q14183, Q6P4G4, Q7Z5G0, Q8IVX0	Gene names	DOC2A
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha) (Doc2).

DOC2A_MOUSE
θ value	θ > 10 (rank : 268)	NC score	0.074294 (rank : 95)
Query Neighborhood Hits	262	Target Neighborhood Hits	140	Shared Neighborhood Hits	19
SwissProt Accessions	Q7TNF0	Gene names	Doc2a
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha).

DOC2B_HUMAN
θ value	θ > 10 (rank : 269)	NC score	0.071916 (rank : 96)
Query Neighborhood Hits	262	Target Neighborhood Hits	150	Shared Neighborhood Hits	20
SwissProt Accessions	Q14184	Gene names	DOC2B
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

DOC2B_MOUSE
θ value	θ > 10 (rank : 270)	NC score	0.071056 (rank : 99)
Query Neighborhood Hits	262	Target Neighborhood Hits	169	Shared Neighborhood Hits	23
SwissProt Accessions	P70169, Q6NXK3	Gene names	Doc2b
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

DOC2G_MOUSE
θ value	θ > 10 (rank : 271)	NC score	0.058621 (rank : 121)
Query Neighborhood Hits	262	Target Neighborhood Hits	125	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ESN1, Q6P8R8	Gene names	Doc2g
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein gamma (Doc2-gamma).

K1333_MOUSE
θ value	θ > 10 (rank : 272)	NC score	0.062959 (rank : 108)
Query Neighborhood Hits	262	Target Neighborhood Hits	53	Shared Neighborhood Hits	13
SwissProt Accessions	Q5RJY2, Q6ZPT7, Q8BNA4	Gene names	Kiaa1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

MDC1_HUMAN
θ value	θ > 10 (rank : 273)	NC score	0.054966 (rank : 130)
Query Neighborhood Hits	262	Target Neighborhood Hits	1446	Shared Neighborhood Hits	123
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

PA24B_MOUSE
θ value	θ > 10 (rank : 274)	NC score	0.058420 (rank : 122)
Query Neighborhood Hits	262	Target Neighborhood Hits	102	Shared Neighborhood Hits	16
SwissProt Accessions	Q4QQM1, Q80VV8, Q91W88	Gene names	Pla2g4b
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

RASL1_HUMAN
θ value	θ > 10 (rank : 275)	NC score	0.075982 (rank : 92)
Query Neighborhood Hits	262	Target Neighborhood Hits	142	Shared Neighborhood Hits	20
SwissProt Accessions	O95294, Q52M03, Q96CC7	Gene names	RASAL1, RASAL
Domain Architecture
Description	RasGAP-activating-like protein 1.

RASL1_MOUSE
θ value	θ > 10 (rank : 276)	NC score	0.071521 (rank : 97)
Query Neighborhood Hits	262	Target Neighborhood Hits	148	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z268	Gene names	Rasal1, Rasal
Domain Architecture
Description	RasGAP-activating-like protein 1.

RASL2_HUMAN
θ value	θ > 10 (rank : 277)	NC score	0.070261 (rank : 100)
Query Neighborhood Hits	262	Target Neighborhood Hits	161	Shared Neighborhood Hits	20
SwissProt Accessions	O43374, O60286, Q86UW3, Q96QU0	Gene names	RASA4, CAPRI, GAPL, KIAA0538
Domain Architecture
Description	Ras GTPase-activating protein 4 (RasGAP-activating-like protein 2) (Calcium-promoted Ras inactivator).

RCBT1_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.059170 (rank : 118)
Query Neighborhood Hits	262	Target Neighborhood Hits	158	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NDN9, Q969U9	Gene names	RCBTB1, CLLD7, E4.5
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 1 (Regulator of chromosome condensation and BTB domain-containing protein 1) (Chronic lymphocytic leukemia deletion region gene 7 protein) (CLL deletion region gene 7 protein).

RCBT1_MOUSE
θ value	θ > 10 (rank : 279)	NC score	0.060762 (rank : 113)
Query Neighborhood Hits	262	Target Neighborhood Hits	157	Shared Neighborhood Hits	4
SwissProt Accessions	Q6NXM2, Q8BTZ6, Q8BZV0	Gene names	Rcbtb1
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 1 (Regulator of chromosome condensation and BTB domain-containing protein 1).

RCBT2_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.065151 (rank : 104)
Query Neighborhood Hits	262	Target Neighborhood Hits	158	Shared Neighborhood Hits	6
SwissProt Accessions	O95199	Gene names	RCBTB2, CHC1L, RLG
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 2 (Regulator of chromosome condensation and BTB domain-containing protein 2) (Chromosome condensation 1-like) (CHC1-L) (RCC1-like G exchanging factor).

RCBT2_MOUSE
θ value	θ > 10 (rank : 281)	NC score	0.066065 (rank : 103)
Query Neighborhood Hits	262	Target Neighborhood Hits	156	Shared Neighborhood Hits	6
SwissProt Accessions	Q99LJ7, Q3TUA3, Q8BMG2	Gene names	Rcbtb2, Chc1l
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 2 (Regulator of chromosome condensation and BTB domain-containing protein 2) (Chromosome condensation 1-like).

RCC1_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.080111 (rank : 88)
Query Neighborhood Hits	262	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	P18754	Gene names	RCC1, CHC1
Domain Architecture
Description	Regulator of chromosome condensation (Chromosome condensation protein 1) (Cell cycle regulatory protein).

RCC1_MOUSE
θ value	θ > 10 (rank : 283)	NC score	0.078021 (rank : 89)
Query Neighborhood Hits	262	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VE37, Q3UDB6	Gene names	Rcc1, Chc1
Domain Architecture	No domain graphic available
Description	Regulator of chromosome condensation (Chromosome condensation protein 1).

RCC2_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.082569 (rank : 83)
Query Neighborhood Hits	262	Target Neighborhood Hits	36	Shared Neighborhood Hits	6
SwissProt Accessions	Q9P258, Q8IVL9, Q9BSN6, Q9NPV8	Gene names	RCC2, KIAA1470, TD60
Domain Architecture	No domain graphic available
Description	Protein RCC2 (Telophase disk protein of 60 kDa) (RCC1-like protein TD- 60).

RCC2_MOUSE
θ value	θ > 10 (rank : 285)	NC score	0.082098 (rank : 84)
Query Neighborhood Hits	262	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BK67, Q6ZPQ0	Gene names	Rcc2, Kiaa1470
Domain Architecture	No domain graphic available
Description	Protein RCC2.

RIMS1_HUMAN
θ value	θ > 10 (rank : 286)	NC score	0.054137 (rank : 132)
Query Neighborhood Hits	262	Target Neighborhood Hits	437	Shared Neighborhood Hits	43
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

RP3A_HUMAN
θ value	θ > 10 (rank : 287)	NC score	0.061440 (rank : 110)
Query Neighborhood Hits	262	Target Neighborhood Hits	305	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

RP3A_MOUSE
θ value	θ > 10 (rank : 288)	NC score	0.058649 (rank : 120)
Query Neighborhood Hits	262	Target Neighborhood Hits	510	Shared Neighborhood Hits	53
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

RPGR_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.085312 (rank : 78)
Query Neighborhood Hits	262	Target Neighborhood Hits	279	Shared Neighborhood Hits	19
SwissProt Accessions	Q92834, O00702, O00737, Q8N5T6, Q93039, Q9HD29, Q9UMR1	Gene names	RPGR, RP3, XLRP3
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator.

RPGR_MOUSE
θ value	θ > 10 (rank : 290)	NC score	0.080531 (rank : 87)
Query Neighborhood Hits	262	Target Neighborhood Hits	281	Shared Neighborhood Hits	17
SwissProt Accessions	Q9R0X5, O88408, Q9CU92	Gene names	Rpgr
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator (mRpgr).

SRGEF_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.085773 (rank : 76)
Query Neighborhood Hits	262	Target Neighborhood Hits	33	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UGK8, Q9UGK9	Gene names	SERGEF, DELGEF, GNEFR
Domain Architecture	No domain graphic available
Description	Secretion-regulating guanine nucleotide exchange factor (Guanine nucleotide exchange factor-related protein) (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF).

SRGEF_MOUSE
θ value	θ > 10 (rank : 292)	NC score	0.083531 (rank : 82)
Query Neighborhood Hits	262	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	Q80YD6, Q9QXB7	Gene names	Sergef, Delgef, Gnefr
Domain Architecture	No domain graphic available
Description	Secretion-regulating guanine nucleotide exchange factor (Guanine nucleotide exchange factor-related protein) (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF).

SYT10_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.059079 (rank : 119)
Query Neighborhood Hits	262	Target Neighborhood Hits	134	Shared Neighborhood Hits	19
SwissProt Accessions	Q6XYQ8	Gene names	SYT10
Domain Architecture	No domain graphic available
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

SYT10_MOUSE
θ value	θ > 10 (rank : 294)	NC score	0.057460 (rank : 124)
Query Neighborhood Hits	262	Target Neighborhood Hits	133	Shared Neighborhood Hits	19
SwissProt Accessions	Q9R0N4	Gene names	Syt10
Domain Architecture
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

SYT1_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.061284 (rank : 111)
Query Neighborhood Hits	262	Target Neighborhood Hits	150	Shared Neighborhood Hits	21
SwissProt Accessions	P21579	Gene names	SYT1, SYT
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT1_MOUSE
θ value	θ > 10 (rank : 296)	NC score	0.061282 (rank : 112)
Query Neighborhood Hits	262	Target Neighborhood Hits	150	Shared Neighborhood Hits	21
SwissProt Accessions	P46096	Gene names	Syt1
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT2_HUMAN
θ value	θ > 10 (rank : 297)	NC score	0.057425 (rank : 125)
Query Neighborhood Hits	262	Target Neighborhood Hits	142	Shared Neighborhood Hits	21
SwissProt Accessions	Q8N9I0, Q496K5, Q8NBE5	Gene names	SYT2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT2_MOUSE
θ value	θ > 10 (rank : 298)	NC score	0.057539 (rank : 123)
Query Neighborhood Hits	262	Target Neighborhood Hits	143	Shared Neighborhood Hits	21
SwissProt Accessions	P46097, Q8R0E1	Gene names	Syt2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT3_HUMAN
θ value	θ > 10 (rank : 299)	NC score	0.051053 (rank : 143)
Query Neighborhood Hits	262	Target Neighborhood Hits	145	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BQG1, Q8N5Z1, Q8N640	Gene names	SYT3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

SYT3_MOUSE
θ value	θ > 10 (rank : 300)	NC score	0.051582 (rank : 139)
Query Neighborhood Hits	262	Target Neighborhood Hits	147	Shared Neighborhood Hits	19
SwissProt Accessions	O35681, P97791, Q80WV1	Gene names	Syt3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

SYT5_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.062800 (rank : 109)
Query Neighborhood Hits	262	Target Neighborhood Hits	138	Shared Neighborhood Hits	21
SwissProt Accessions	O00445, Q86X72	Gene names	SYT5
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV).

SYT5_MOUSE
θ value	θ > 10 (rank : 302)	NC score	0.056599 (rank : 126)
Query Neighborhood Hits	262	Target Neighborhood Hits	140	Shared Neighborhood Hits	19
SwissProt Accessions	Q9R0N5	Gene names	Syt5, Syt9
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV) (Synaptotagmin IX).

SYT6_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.050799 (rank : 144)
Query Neighborhood Hits	262	Target Neighborhood Hits	138	Shared Neighborhood Hits	18
SwissProt Accessions	Q5T7P8	Gene names	SYT6
Domain Architecture	No domain graphic available
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

SYT6_MOUSE
θ value	θ > 10 (rank : 304)	NC score	0.052316 (rank : 138)
Query Neighborhood Hits	262	Target Neighborhood Hits	132	Shared Neighborhood Hits	19
SwissProt Accessions	Q9R0N8	Gene names	Syt6
Domain Architecture
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

SYT7_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.060415 (rank : 114)
Query Neighborhood Hits	262	Target Neighborhood Hits	137	Shared Neighborhood Hits	20
SwissProt Accessions	O43581	Gene names	SYT7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

SYT7_MOUSE
θ value	θ > 10 (rank : 306)	NC score	0.059586 (rank : 116)
Query Neighborhood Hits	262	Target Neighborhood Hits	137	Shared Neighborhood Hits	19
SwissProt Accessions	Q9R0N7	Gene names	Syt7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

SYT9_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.053739 (rank : 134)
Query Neighborhood Hits	262	Target Neighborhood Hits	144	Shared Neighborhood Hits	18
SwissProt Accessions	Q86SS6	Gene names	SYT9
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX).

SYT9_MOUSE
θ value	θ > 10 (rank : 308)	NC score	0.054988 (rank : 129)
Query Neighborhood Hits	262	Target Neighborhood Hits	148	Shared Neighborhood Hits	18
SwissProt Accessions	Q9R0N9, Q8C280	Gene names	Syt9, Syt5
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX) (Synaptotagmin V).

SYTL2_HUMAN
θ value	θ > 10 (rank : 309)	NC score	0.051559 (rank : 140)
Query Neighborhood Hits	262	Target Neighborhood Hits	248	Shared Neighborhood Hits	31
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

TGON2_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.052621 (rank : 136)
Query Neighborhood Hits	262	Target Neighborhood Hits	1037	Shared Neighborhood Hits	96
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TOLIP_HUMAN
θ value	θ > 10 (rank : 311)	NC score	0.064856 (rank : 105)
Query Neighborhood Hits	262	Target Neighborhood Hits	20	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H0E2, Q9H9E6, Q9UJ69	Gene names	TOLLIP
Domain Architecture
Description	Toll-interacting protein.

TOLIP_MOUSE
θ value	θ > 10 (rank : 312)	NC score	0.070050 (rank : 102)
Query Neighborhood Hits	262	Target Neighborhood Hits	24	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QZ06, Q543N1, Q9D5P5	Gene names	Tollip
Domain Architecture
Description	Toll-interacting protein.

UN13A_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.083729 (rank : 81)
Query Neighborhood Hits	262	Target Neighborhood Hits	285	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

UN13B_HUMAN
θ value	θ > 10 (rank : 314)	NC score	0.085220 (rank : 80)
Query Neighborhood Hits	262	Target Neighborhood Hits	217	Shared Neighborhood Hits	20
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

UN13B_MOUSE
θ value	θ > 10 (rank : 315)	NC score	0.085234 (rank : 79)
Query Neighborhood Hits	262	Target Neighborhood Hits	210	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

UN13D_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.060107 (rank : 115)
Query Neighborhood Hits	262	Target Neighborhood Hits	117	Shared Neighborhood Hits	15
SwissProt Accessions	Q70J99, Q9H7K5	Gene names	UNC13D
Domain Architecture	No domain graphic available
Description	Unc-13 homolog D (Munc13-4).

WBP4_HUMAN
θ value	θ > 10 (rank : 317)	NC score	0.052899 (rank : 135)
Query Neighborhood Hits	262	Target Neighborhood Hits	86	Shared Neighborhood Hits	22
SwissProt Accessions	O75554	Gene names	WBP4, FBP21, FNBP21
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21).

WBS16_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.075776 (rank : 93)
Query Neighborhood Hits	262	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q96I51, Q548B1, Q9H0G7	Gene names	WBSCR16
Domain Architecture	No domain graphic available
Description	Williams-Beuren syndrome chromosome region 16 protein (RCC1-like G exchanging factor-like protein).

WBS16_MOUSE
θ value	θ > 10 (rank : 319)	NC score	0.077395 (rank : 90)
Query Neighborhood Hits	262	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CYF5	Gene names	Wbscr16
Domain Architecture	No domain graphic available
Description	Williams-Beuren syndrome chromosome region 16 protein homolog.

WWC3_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.051233 (rank : 141)
Query Neighborhood Hits	262	Target Neighborhood Hits	193	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ULE0, Q659C1, Q9BTQ1	Gene names	WWC3, KIAA1280
Domain Architecture	No domain graphic available
Description	WWC family member 3.

Hits sorted by NC score

WWP1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	262	Target Neighborhood Hits	262	Shared Neighborhood Hits	262
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

WWP1_MOUSE
NC score	0.988077 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	262	Target Neighborhood Hits	138	Shared Neighborhood Hits	100
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

WWP2_MOUSE
NC score	0.983562 (rank : 3)	θ value	0 (rank : 6)
Query Neighborhood Hits	262	Target Neighborhood Hits	118	Shared Neighborhood Hits	80
SwissProt Accessions	Q9DBH0, Q8BTG4, Q923F6	Gene names	Wwp2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2).

ITCH_MOUSE
NC score	0.983097 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	262	Target Neighborhood Hits	127	Shared Neighborhood Hits	80
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

WWP2_HUMAN
NC score	0.982917 (rank : 5)	θ value	0 (rank : 5)
Query Neighborhood Hits	262	Target Neighborhood Hits	177	Shared Neighborhood Hits	98
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

ITCH_HUMAN
NC score	0.976085 (rank : 6)	θ value	0 (rank : 1)
Query Neighborhood Hits	262	Target Neighborhood Hits	162	Shared Neighborhood Hits	84
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

SMUF2_HUMAN
NC score	0.952988 (rank : 7)	θ value	3.88293e-136 (rank : 10)
Query Neighborhood Hits	262	Target Neighborhood Hits	142	Shared Neighborhood Hits	77
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

SMUF1_MOUSE
NC score	0.945746 (rank : 8)	θ value	7.33985e-127 (rank : 12)
Query Neighborhood Hits	262	Target Neighborhood Hits	142	Shared Neighborhood Hits	67
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

SMUF1_HUMAN
NC score	0.942545 (rank : 9)	θ value	1.38424e-125 (rank : 13)
Query Neighborhood Hits	262	Target Neighborhood Hits	135	Shared Neighborhood Hits	64
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

NEDD4_MOUSE
NC score	0.910203 (rank : 10)	θ value	1.4755e-135 (rank : 11)
Query Neighborhood Hits	262	Target Neighborhood Hits	212	Shared Neighborhood Hits	88
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

NEDD4_HUMAN
NC score	0.906844 (rank : 11)	θ value	3.27947e-143 (rank : 9)
Query Neighborhood Hits	262	Target Neighborhood Hits	214	Shared Neighborhood Hits	85
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

NED4L_MOUSE
NC score	0.892687 (rank : 12)	θ value	5.9766e-145 (rank : 7)
Query Neighborhood Hits	262	Target Neighborhood Hits	231	Shared Neighborhood Hits	87
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NED4L_HUMAN
NC score	0.891907 (rank : 13)	θ value	1.12714e-143 (rank : 8)
Query Neighborhood Hits	262	Target Neighborhood Hits	238	Shared Neighborhood Hits	88
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

HECD2_MOUSE
NC score	0.875277 (rank : 14)	θ value	9.16162e-53 (rank : 16)
Query Neighborhood Hits	262	Target Neighborhood Hits	38	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CDU6, Q8CBQ9	Gene names	Hectd2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

HECD2_HUMAN
NC score	0.872417 (rank : 15)	θ value	6.56568e-51 (rank : 18)
Query Neighborhood Hits	262	Target Neighborhood Hits	41	Shared Neighborhood Hits	33
SwissProt Accessions	Q5U5R9, Q5VZ97, Q5VZ99, Q8TCP5	Gene names	HECTD2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

UBE3A_HUMAN
NC score	0.867973 (rank : 16)	θ value	1.32293e-51 (rank : 17)
Query Neighborhood Hits	262	Target Neighborhood Hits	49	Shared Neighborhood Hits	33
SwissProt Accessions	Q05086, P78355, Q93066, Q9UEP4, Q9UEP5, Q9UEP6, Q9UEP7, Q9UEP8, Q9UEP9	Gene names	UBE3A, E6AP
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Oncogenic protein-associated protein E6-AP) (Human papillomavirus E6-associated protein) (NY-REN-54 antigen).

K0317_HUMAN
NC score	0.867609 (rank : 17)	θ value	1.08474e-45 (rank : 20)
Query Neighborhood Hits	262	Target Neighborhood Hits	46	Shared Neighborhood Hits	34
SwissProt Accessions	O15033, Q7LDY1, Q8IYY9	Gene names	KIAA0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

K0317_MOUSE
NC score	0.866963 (rank : 18)	θ value	4.122e-45 (rank : 21)
Query Neighborhood Hits	262	Target Neighborhood Hits	43	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CHG5, Q6P9Q1, Q80YC4, Q8C5W5	Gene names	Kiaa0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

HUWE1_MOUSE
NC score	0.864459 (rank : 19)	θ value	7.93343e-89 (rank : 15)
Query Neighborhood Hits	262	Target Neighborhood Hits	406	Shared Neighborhood Hits	72
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

HUWE1_HUMAN
NC score	0.863292 (rank : 20)	θ value	7.93343e-89 (rank : 14)
Query Neighborhood Hits	262	Target Neighborhood Hits	443	Shared Neighborhood Hits	70
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

UBE3A_MOUSE
NC score	0.861364 (rank : 21)	θ value	6.35935e-46 (rank : 19)
Query Neighborhood Hits	262	Target Neighborhood Hits	47	Shared Neighborhood Hits	34
SwissProt Accessions	O08759, P97482	Gene names	Ube3a
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (Oncogenic protein- associated protein E6-AP).

UBE3C_HUMAN
NC score	0.849878 (rank : 22)	θ value	4.2656e-42 (rank : 22)
Query Neighborhood Hits	262	Target Neighborhood Hits	51	Shared Neighborhood Hits	33
SwissProt Accessions	Q15386, Q8TC15, Q96CR4, Q9UDU3	Gene names	UBE3C, KIAA0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

UBE3C_MOUSE
NC score	0.848290 (rank : 23)	θ value	3.61106e-41 (rank : 23)
Query Neighborhood Hits	262	Target Neighborhood Hits	48	Shared Neighborhood Hits	33
SwissProt Accessions	Q80U95, Q8BQZ6, Q8C7W6, Q8CDJ1, Q8VDL5	Gene names	Ube3c, Kiaa0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

TRIPC_HUMAN
NC score	0.789175 (rank : 24)	θ value	1.52067e-31 (rank : 26)
Query Neighborhood Hits	262	Target Neighborhood Hits	319	Shared Neighborhood Hits	56
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

HERC5_HUMAN
NC score	0.722384 (rank : 25)	θ value	7.54701e-31 (rank : 28)
Query Neighborhood Hits	262	Target Neighborhood Hits	66	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UII4	Gene names	HERC5, CEB1, CEBP1
Domain Architecture
Description	HECT domain and RCC1-like domain-containing protein 5 (Cyclin-E- binding protein 1).

HERC3_HUMAN
NC score	0.718958 (rank : 26)	θ value	6.81017e-40 (rank : 24)
Query Neighborhood Hits	262	Target Neighborhood Hits	62	Shared Neighborhood Hits	33
SwissProt Accessions	Q15034	Gene names	HERC3, KIAA0032
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain protein 3.

HECD3_MOUSE
NC score	0.684342 (rank : 27)	θ value	9.90251e-15 (rank : 30)
Query Neighborhood Hits	262	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	Q3U487, Q3TN76, Q641P3, Q8BQ74, Q8R1L6	Gene names	Hectd3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

HECD3_HUMAN
NC score	0.678926 (rank : 28)	θ value	4.91457e-14 (rank : 31)
Query Neighborhood Hits	262	Target Neighborhood Hits	49	Shared Neighborhood Hits	33
SwissProt Accessions	Q5T447, Q5T448, Q9H783	Gene names	HECTD3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

EDD1_MOUSE
NC score	0.645148 (rank : 29)	θ value	1.09485e-13 (rank : 34)
Query Neighborhood Hits	262	Target Neighborhood Hits	167	Shared Neighborhood Hits	41
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

EDD1_HUMAN
NC score	0.643339 (rank : 30)	θ value	1.09485e-13 (rank : 33)
Query Neighborhood Hits	262	Target Neighborhood Hits	170	Shared Neighborhood Hits	39
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

HERC2_MOUSE
NC score	0.615190 (rank : 31)	θ value	5.22648e-32 (rank : 25)
Query Neighborhood Hits	262	Target Neighborhood Hits	167	Shared Neighborhood Hits	40
SwissProt Accessions	Q4U2R1, O88473, Q3TRJ8, Q3TS47, Q3TST2, Q3UFQ6, Q3URH7, Q5DU32, Q7TPR5, Q80VV7, Q9QYT1, Q9Z168, Q9Z171	Gene names	Herc2, jdf2, Kiaa0393, rjs
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

HERC2_HUMAN
NC score	0.611025 (rank : 32)	θ value	2.59387e-31 (rank : 27)
Query Neighborhood Hits	262	Target Neighborhood Hits	163	Shared Neighborhood Hits	41
SwissProt Accessions	O95714, Q86SV7, Q86SV8, Q86SV9, Q86YY3, Q86YY4, Q86YY5, Q86YY6, Q86YY7, Q86YY8, Q86YY9, Q86YZ0, Q86YZ1	Gene names	HERC2
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

HECD1_HUMAN
NC score	0.558530 (rank : 33)	θ value	8.08199e-25 (rank : 29)
Query Neighborhood Hits	262	Target Neighborhood Hits	371	Shared Neighborhood Hits	35
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

YAP1_MOUSE
NC score	0.553415 (rank : 34)	θ value	8.38298e-14 (rank : 32)
Query Neighborhood Hits	262	Target Neighborhood Hits	96	Shared Neighborhood Hits	55
SwissProt Accessions	P46938, Q52KJ5	Gene names	Yap1, Yap, Yap65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

SAV1_HUMAN
NC score	0.528632 (rank : 35)	θ value	1.74796e-11 (rank : 40)
Query Neighborhood Hits	262	Target Neighborhood Hits	51	Shared Neighborhood Hits	43
SwissProt Accessions	Q9H4B6, Q6IA58, Q9H949, Q9HAK9	Gene names	SAV1, WW45
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (hWW45).

SAV1_MOUSE
NC score	0.528156 (rank : 36)	θ value	1.74796e-11 (rank : 41)
Query Neighborhood Hits	262	Target Neighborhood Hits	48	Shared Neighborhood Hits	41
SwissProt Accessions	Q8VEB2, Q9D9N9, Q9ER46	Gene names	Sav1, Ww45, Wwp3
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (mWW45).

PINL_HUMAN
NC score	0.444130 (rank : 37)	θ value	0.00020696 (rank : 55)
Query Neighborhood Hits	262	Target Neighborhood Hits	47	Shared Neighborhood Hits	44
SwissProt Accessions	O15428	Gene names	PIN1L
Domain Architecture
Description	PIN1-like protein.

WWC1_HUMAN
NC score	0.443207 (rank : 38)	θ value	7.09661e-13 (rank : 35)
Query Neighborhood Hits	262	Target Neighborhood Hits	290	Shared Neighborhood Hits	50
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

WWC1_MOUSE
NC score	0.442147 (rank : 39)	θ value	7.09661e-13 (rank : 36)
Query Neighborhood Hits	262	Target Neighborhood Hits	290	Shared Neighborhood Hits	44
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

WWOX_HUMAN
NC score	0.392790 (rank : 40)	θ value	1.02475e-11 (rank : 38)
Query Neighborhood Hits	262	Target Neighborhood Hits	115	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NZC7, Q5MYT5, Q96KM3, Q96RF2, Q9BTT8, Q9NPC9, Q9NRF4, Q9NRF5, Q9NRF6, Q9NRK1, Q9NZC5	Gene names	WWOX, FOR, WOX1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-) (Fragile site FRA16D oxidoreductase).

WWOX_MOUSE
NC score	0.389404 (rank : 41)	θ value	1.02475e-11 (rank : 39)
Query Neighborhood Hits	262	Target Neighborhood Hits	118	Shared Neighborhood Hits	49
SwissProt Accessions	Q91WL8, Q8C8J6, Q920Y2, Q9D2B3, Q9D339, Q9JLF5	Gene names	Wwox, Wox1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-).

PIN1_MOUSE
NC score	0.381806 (rank : 42)	θ value	0.000270298 (rank : 57)
Query Neighborhood Hits	262	Target Neighborhood Hits	60	Shared Neighborhood Hits	46
SwissProt Accessions	Q9QUR7, Q543B3	Gene names	Pin1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

PIN1_HUMAN
NC score	0.379889 (rank : 43)	θ value	0.000270298 (rank : 56)
Query Neighborhood Hits	262	Target Neighborhood Hits	59	Shared Neighborhood Hits	43
SwissProt Accessions	Q13526	Gene names	PIN1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

WWTR1_MOUSE
NC score	0.379666 (rank : 44)	θ value	7.1131e-05 (rank : 51)
Query Neighborhood Hits	262	Target Neighborhood Hits	54	Shared Neighborhood Hits	41
SwissProt Accessions	Q9EPK5, Q99KI4	Gene names	Wwtr1, Taz
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

YAP1_HUMAN
NC score	0.377542 (rank : 45)	θ value	7.1131e-05 (rank : 52)
Query Neighborhood Hits	262	Target Neighborhood Hits	173	Shared Neighborhood Hits	66
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

WWTR1_HUMAN
NC score	0.376999 (rank : 46)	θ value	7.1131e-05 (rank : 50)
Query Neighborhood Hits	262	Target Neighborhood Hits	76	Shared Neighborhood Hits	46
SwissProt Accessions	Q9GZV5, Q8N3P2, Q9Y3W6	Gene names	WWTR1, TAZ
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

BAG3_HUMAN
NC score	0.355536 (rank : 47)	θ value	3.77169e-06 (rank : 46)
Query Neighborhood Hits	262	Target Neighborhood Hits	314	Shared Neighborhood Hits	63
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

MAGI2_MOUSE
NC score	0.321779 (rank : 48)	θ value	1.02475e-11 (rank : 37)
Query Neighborhood Hits	262	Target Neighborhood Hits	370	Shared Neighborhood Hits	62
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

BAG3_MOUSE
NC score	0.313675 (rank : 49)	θ value	2.44474e-05 (rank : 49)
Query Neighborhood Hits	262	Target Neighborhood Hits	513	Shared Neighborhood Hits	83
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

MAGI2_HUMAN
NC score	0.306662 (rank : 50)	θ value	1.25267e-09 (rank : 44)
Query Neighborhood Hits	262	Target Neighborhood Hits	373	Shared Neighborhood Hits	55
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

MAGI1_HUMAN
NC score	0.301216 (rank : 51)	θ value	1.47974e-10 (rank : 43)
Query Neighborhood Hits	262	Target Neighborhood Hits	388	Shared Neighborhood Hits	61
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

MAGI1_MOUSE
NC score	0.300761 (rank : 52)	θ value	1.133e-10 (rank : 42)
Query Neighborhood Hits	262	Target Neighborhood Hits	403	Shared Neighborhood Hits	66
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

PKHA5_HUMAN
NC score	0.285841 (rank : 53)	θ value	1.63604e-09 (rank : 45)
Query Neighborhood Hits	262	Target Neighborhood Hits	455	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

GAS7_HUMAN
NC score	0.264976 (rank : 54)	θ value	9.29e-05 (rank : 53)
Query Neighborhood Hits	262	Target Neighborhood Hits	258	Shared Neighborhood Hits	51
SwissProt Accessions	O60861, O43144	Gene names	GAS7, KIAA0394
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

GAS7_MOUSE
NC score	0.264252 (rank : 55)	θ value	0.000158464 (rank : 54)
Query Neighborhood Hits	262	Target Neighborhood Hits	259	Shared Neighborhood Hits	50
SwissProt Accessions	Q60780, Q9QY25, Q9QY26, Q9QY34	Gene names	Gas7
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

PRP40_MOUSE
NC score	0.228231 (rank : 56)	θ value	6.43352e-06 (rank : 48)
Query Neighborhood Hits	262	Target Neighborhood Hits	447	Shared Neighborhood Hits	60
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

PRP40_HUMAN
NC score	0.227087 (rank : 57)	θ value	6.43352e-06 (rank : 47)
Query Neighborhood Hits	262	Target Neighborhood Hits	442	Shared Neighborhood Hits	54
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

APBB2_HUMAN
NC score	0.180191 (rank : 58)	θ value	0.00035302 (rank : 58)
Query Neighborhood Hits	262	Target Neighborhood Hits	96	Shared Neighborhood Hits	40
SwissProt Accessions	Q92870, Q8IUI6	Gene names	APBB2, FE65L, FE65L1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2 (Fe65-like protein).

STXB4_MOUSE
NC score	0.178384 (rank : 59)	θ value	0.00298849 (rank : 66)
Query Neighborhood Hits	262	Target Neighborhood Hits	629	Shared Neighborhood Hits	53
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

STXB4_HUMAN
NC score	0.177316 (rank : 60)	θ value	0.00298849 (rank : 65)
Query Neighborhood Hits	262	Target Neighborhood Hits	616	Shared Neighborhood Hits	52
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

APBB2_MOUSE
NC score	0.169774 (rank : 61)	θ value	0.00035302 (rank : 59)
Query Neighborhood Hits	262	Target Neighborhood Hits	88	Shared Neighborhood Hits	36
SwissProt Accessions	Q9DBR4, Q6DFX8	Gene names	Apbb2
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2.

SETD2_HUMAN
NC score	0.139854 (rank : 62)	θ value	0.0148317 (rank : 75)
Query Neighborhood Hits	262	Target Neighborhood Hits	412	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

APBB3_HUMAN
NC score	0.133918 (rank : 63)	θ value	0.163984 (rank : 91)
Query Neighborhood Hits	262	Target Neighborhood Hits	36	Shared Neighborhood Hits	27
SwissProt Accessions	O95704, Q9NYX6, Q9NYX7, Q9NYX8	Gene names	APBB3, FE65L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 3 (Fe65-like protein 2) (Fe65L2).

APBB3_MOUSE
NC score	0.132986 (rank : 64)	θ value	0.21417 (rank : 95)
Query Neighborhood Hits	262	Target Neighborhood Hits	32	Shared Neighborhood Hits	26
SwissProt Accessions	Q8R1C9	Gene names	Apbb3
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 3.

RHG12_MOUSE
NC score	0.123610 (rank : 65)	θ value	0.00102713 (rank : 63)
Query Neighborhood Hits	262	Target Neighborhood Hits	204	Shared Neighborhood Hits	38
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

WBP4_MOUSE
NC score	0.114104 (rank : 66)	θ value	6.88961 (rank : 240)
Query Neighborhood Hits	262	Target Neighborhood Hits	100	Shared Neighborhood Hits	36
SwissProt Accessions	Q61048, Q8K1Z9, Q9CS45	Gene names	Wbp4, Fbp21, Fnbp21
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21).

RHG12_HUMAN
NC score	0.109047 (rank : 67)	θ value	0.0148317 (rank : 74)
Query Neighborhood Hits	262	Target Neighborhood Hits	190	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

FA62A_MOUSE
NC score	0.105711 (rank : 68)	θ value	0.813845 (rank : 134)
Query Neighborhood Hits	262	Target Neighborhood Hits	155	Shared Neighborhood Hits	24
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

APBB1_HUMAN
NC score	0.096631 (rank : 69)	θ value	0.279714 (rank : 101)
Query Neighborhood Hits	262	Target Neighborhood Hits	62	Shared Neighborhood Hits	25
SwissProt Accessions	O00213, Q96A93	Gene names	APBB1, FE65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

DRP2_HUMAN
NC score	0.096578 (rank : 70)	θ value	0.365318 (rank : 108)
Query Neighborhood Hits	262	Target Neighborhood Hits	186	Shared Neighborhood Hits	29
SwissProt Accessions	Q13474	Gene names	DRP2
Domain Architecture
Description	Dystrophin-related protein 2.

APBB1_MOUSE
NC score	0.095973 (rank : 71)	θ value	1.38821 (rank : 146)
Query Neighborhood Hits	262	Target Neighborhood Hits	75	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QXJ1, O08642, Q3TPU0, Q8BNF4, Q8BSR9	Gene names	Apbb1, Fe65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

TCRG1_MOUSE
NC score	0.095414 (rank : 72)	θ value	0.00665767 (rank : 69)
Query Neighborhood Hits	262	Target Neighborhood Hits	947	Shared Neighborhood Hits	82
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TCRG1_HUMAN
NC score	0.095198 (rank : 73)	θ value	0.00869519 (rank : 70)
Query Neighborhood Hits	262	Target Neighborhood Hits	929	Shared Neighborhood Hits	76
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

FA62A_HUMAN
NC score	0.089954 (rank : 74)	θ value	4.03905 (rank : 194)
Query Neighborhood Hits	262	Target Neighborhood Hits	168	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

DGCR8_HUMAN
NC score	0.087184 (rank : 75)	θ value	0.21417 (rank : 96)
Query Neighborhood Hits	262	Target Neighborhood Hits	72	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WYQ5, Q6DCB2, Q6MZE9, Q6Y2L0, Q96G39, Q96GP8, Q9H6L8, Q9H6T7, Q9NRW2	Gene names	DGCR8, C22orf12, DGCRK6
Domain Architecture
Description	DGCR8 protein (DiGeorge syndrome critical region 8).

SRGEF_HUMAN
NC score	0.085773 (rank : 76)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	262	Target Neighborhood Hits	33	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UGK8, Q9UGK9	Gene names	SERGEF, DELGEF, GNEFR
Domain Architecture	No domain graphic available
Description	Secretion-regulating guanine nucleotide exchange factor (Guanine nucleotide exchange factor-related protein) (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF).

DGCR8_MOUSE
NC score	0.085482 (rank : 77)	θ value	0.21417 (rank : 97)
Query Neighborhood Hits	262	Target Neighborhood Hits	70	Shared Neighborhood Hits	16
SwissProt Accessions	Q9EQM6	Gene names	Dgcr8
Domain Architecture	No domain graphic available
Description	DGCR8 protein (DiGeorge syndrome critical region 8 homolog) (Gy1).

RPGR_HUMAN
NC score	0.085312 (rank : 78)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	262	Target Neighborhood Hits	279	Shared Neighborhood Hits	19
SwissProt Accessions	Q92834, O00702, O00737, Q8N5T6, Q93039, Q9HD29, Q9UMR1	Gene names	RPGR, RP3, XLRP3
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator.

UN13B_MOUSE
NC score	0.085234 (rank : 79)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	262	Target Neighborhood Hits	210	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

UN13B_HUMAN
NC score	0.085220 (rank : 80)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	262	Target Neighborhood Hits	217	Shared Neighborhood Hits	20
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

UN13A_HUMAN
NC score	0.083729 (rank : 81)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	262	Target Neighborhood Hits	285	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

SRGEF_MOUSE
NC score	0.083531 (rank : 82)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	262	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	Q80YD6, Q9QXB7	Gene names	Sergef, Delgef, Gnefr
Domain Architecture	No domain graphic available
Description	Secretion-regulating guanine nucleotide exchange factor (Guanine nucleotide exchange factor-related protein) (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF).

RCC2_HUMAN
NC score	0.082569 (rank : 83)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	262	Target Neighborhood Hits	36	Shared Neighborhood Hits	6
SwissProt Accessions	Q9P258, Q8IVL9, Q9BSN6, Q9NPV8	Gene names	RCC2, KIAA1470, TD60
Domain Architecture	No domain graphic available
Description	Protein RCC2 (Telophase disk protein of 60 kDa) (RCC1-like protein TD- 60).

RCC2_MOUSE
NC score	0.082098 (rank : 84)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	262	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BK67, Q6ZPQ0	Gene names	Rcc2, Kiaa1470
Domain Architecture	No domain graphic available
Description	Protein RCC2.

RIMS2_HUMAN
NC score	0.080769 (rank : 85)	θ value	0.279714 (rank : 105)
Query Neighborhood Hits	262	Target Neighborhood Hits	342	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
NC score	0.080637 (rank : 86)	θ value	0.279714 (rank : 106)
Query Neighborhood Hits	262	Target Neighborhood Hits	376	Shared Neighborhood Hits	41
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

RPGR_MOUSE
NC score	0.080531 (rank : 87)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	262	Target Neighborhood Hits	281	Shared Neighborhood Hits	17
SwissProt Accessions	Q9R0X5, O88408, Q9CU92	Gene names	Rpgr
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator (mRpgr).

RCC1_HUMAN
NC score	0.080111 (rank : 88)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	262	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	P18754	Gene names	RCC1, CHC1
Domain Architecture
Description	Regulator of chromosome condensation (Chromosome condensation protein 1) (Cell cycle regulatory protein).

RCC1_MOUSE
NC score	0.078021 (rank : 89)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	262	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VE37, Q3UDB6	Gene names	Rcc1, Chc1
Domain Architecture	No domain graphic available
Description	Regulator of chromosome condensation (Chromosome condensation protein 1).

WBS16_MOUSE
NC score	0.077395 (rank : 90)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	262	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CYF5	Gene names	Wbscr16
Domain Architecture	No domain graphic available
Description	Williams-Beuren syndrome chromosome region 16 protein homolog.

PCLO_MOUSE
NC score	0.076169 (rank : 91)	θ value	0.62314 (rank : 127)
Query Neighborhood Hits	262	Target Neighborhood Hits	2275	Shared Neighborhood Hits	139
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RASL1_HUMAN
NC score	0.075982 (rank : 92)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	262	Target Neighborhood Hits	142	Shared Neighborhood Hits	20
SwissProt Accessions	O95294, Q52M03, Q96CC7	Gene names	RASAL1, RASAL
Domain Architecture
Description	RasGAP-activating-like protein 1.

WBS16_HUMAN
NC score	0.075776 (rank : 93)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	262	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q96I51, Q548B1, Q9H0G7	Gene names	WBSCR16
Domain Architecture	No domain graphic available
Description	Williams-Beuren syndrome chromosome region 16 protein (RCC1-like G exchanging factor-like protein).

PCLO_HUMAN
NC score	0.075678 (rank : 94)	θ value	1.81305 (rank : 155)
Query Neighborhood Hits	262	Target Neighborhood Hits	2046	Shared Neighborhood Hits	143
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

DOC2A_MOUSE
NC score	0.074294 (rank : 95)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	262	Target Neighborhood Hits	140	Shared Neighborhood Hits	19
SwissProt Accessions	Q7TNF0	Gene names	Doc2a
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha).

DOC2B_HUMAN
NC score	0.071916 (rank : 96)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	262	Target Neighborhood Hits	150	Shared Neighborhood Hits	20
SwissProt Accessions	Q14184	Gene names	DOC2B
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

RASL1_MOUSE
NC score	0.071521 (rank : 97)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	262	Target Neighborhood Hits	148	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z268	Gene names	Rasal1, Rasal
Domain Architecture
Description	RasGAP-activating-like protein 1.

CK024_MOUSE
NC score	0.071354 (rank : 98)	θ value	0.47712 (rank : 113)
Query Neighborhood Hits	262	Target Neighborhood Hits	307	Shared Neighborhood Hits	66
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

DOC2B_MOUSE
NC score	0.071056 (rank : 99)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	262	Target Neighborhood Hits	169	Shared Neighborhood Hits	23
SwissProt Accessions	P70169, Q6NXK3	Gene names	Doc2b
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

RASL2_HUMAN
NC score	0.070261 (rank : 100)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	262	Target Neighborhood Hits	161	Shared Neighborhood Hits	20
SwissProt Accessions	O43374, O60286, Q86UW3, Q96QU0	Gene names	RASA4, CAPRI, GAPL, KIAA0538
Domain Architecture
Description	Ras GTPase-activating protein 4 (RasGAP-activating-like protein 2) (Calcium-promoted Ras inactivator).

DOC2A_HUMAN
NC score	0.070189 (rank : 101)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	262	Target Neighborhood Hits	144	Shared Neighborhood Hits	18
SwissProt Accessions	Q14183, Q6P4G4, Q7Z5G0, Q8IVX0	Gene names	DOC2A
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha) (Doc2).

TOLIP_MOUSE
NC score	0.070050 (rank : 102)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	262	Target Neighborhood Hits	24	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QZ06, Q543N1, Q9D5P5	Gene names	Tollip
Domain Architecture
Description	Toll-interacting protein.

RCBT2_MOUSE
NC score	0.066065 (rank : 103)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	262	Target Neighborhood Hits	156	Shared Neighborhood Hits	6
SwissProt Accessions	Q99LJ7, Q3TUA3, Q8BMG2	Gene names	Rcbtb2, Chc1l
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 2 (Regulator of chromosome condensation and BTB domain-containing protein 2) (Chromosome condensation 1-like).

RCBT2_HUMAN
NC score	0.065151 (rank : 104)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	262	Target Neighborhood Hits	158	Shared Neighborhood Hits	6
SwissProt Accessions	O95199	Gene names	RCBTB2, CHC1L, RLG
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 2 (Regulator of chromosome condensation and BTB domain-containing protein 2) (Chromosome condensation 1-like) (CHC1-L) (RCC1-like G exchanging factor).

TOLIP_HUMAN
NC score	0.064856 (rank : 105)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	262	Target Neighborhood Hits	20	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H0E2, Q9H9E6, Q9UJ69	Gene names	TOLLIP
Domain Architecture
Description	Toll-interacting protein.

MUC1_MOUSE
NC score	0.063575 (rank : 106)	θ value	0.00102713 (rank : 62)
Query Neighborhood Hits	262	Target Neighborhood Hits	388	Shared Neighborhood Hits	57
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

MUC13_MOUSE
NC score	0.063204 (rank : 107)	θ value	0.00102713 (rank : 61)
Query Neighborhood Hits	262	Target Neighborhood Hits	447	Shared Neighborhood Hits	42
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

K1333_MOUSE
NC score	0.062959 (rank : 108)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	262	Target Neighborhood Hits	53	Shared Neighborhood Hits	13
SwissProt Accessions	Q5RJY2, Q6ZPT7, Q8BNA4	Gene names	Kiaa1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

SYT5_HUMAN
NC score	0.062800 (rank : 109)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	262	Target Neighborhood Hits	138	Shared Neighborhood Hits	21
SwissProt Accessions	O00445, Q86X72	Gene names	SYT5
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV).

RP3A_HUMAN
NC score	0.061440 (rank : 110)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	262	Target Neighborhood Hits	305	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SYT1_HUMAN
NC score	0.061284 (rank : 111)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	262	Target Neighborhood Hits	150	Shared Neighborhood Hits	21
SwissProt Accessions	P21579	Gene names	SYT1, SYT
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT1_MOUSE
NC score	0.061282 (rank : 112)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	262	Target Neighborhood Hits	150	Shared Neighborhood Hits	21
SwissProt Accessions	P46096	Gene names	Syt1
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

RCBT1_MOUSE
NC score	0.060762 (rank : 113)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	262	Target Neighborhood Hits	157	Shared Neighborhood Hits	4
SwissProt Accessions	Q6NXM2, Q8BTZ6, Q8BZV0	Gene names	Rcbtb1
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 1 (Regulator of chromosome condensation and BTB domain-containing protein 1).

SYT7_HUMAN
NC score	0.060415 (rank : 114)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	262	Target Neighborhood Hits	137	Shared Neighborhood Hits	20
SwissProt Accessions	O43581	Gene names	SYT7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

UN13D_HUMAN
NC score	0.060107 (rank : 115)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	262	Target Neighborhood Hits	117	Shared Neighborhood Hits	15
SwissProt Accessions	Q70J99, Q9H7K5	Gene names	UNC13D
Domain Architecture	No domain graphic available
Description	Unc-13 homolog D (Munc13-4).

SYT7_MOUSE
NC score	0.059586 (rank : 116)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	262	Target Neighborhood Hits	137	Shared Neighborhood Hits	19
SwissProt Accessions	Q9R0N7	Gene names	Syt7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

NACAM_MOUSE
NC score	0.059344 (rank : 117)	θ value	0.21417 (rank : 98)
Query Neighborhood Hits	262	Target Neighborhood Hits	1866	Shared Neighborhood Hits	136
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

RCBT1_HUMAN
NC score	0.059170 (rank : 118)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	262	Target Neighborhood Hits	158	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NDN9, Q969U9	Gene names	RCBTB1, CLLD7, E4.5
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 1 (Regulator of chromosome condensation and BTB domain-containing protein 1) (Chronic lymphocytic leukemia deletion region gene 7 protein) (CLL deletion region gene 7 protein).

SYT10_HUMAN
NC score	0.059079 (rank : 119)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	262	Target Neighborhood Hits	134	Shared Neighborhood Hits	19
SwissProt Accessions	Q6XYQ8	Gene names	SYT10
Domain Architecture	No domain graphic available
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

RP3A_MOUSE
NC score	0.058649 (rank : 120)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	262	Target Neighborhood Hits	510	Shared Neighborhood Hits	53
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

DOC2G_MOUSE
NC score	0.058621 (rank : 121)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	262	Target Neighborhood Hits	125	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ESN1, Q6P8R8	Gene names	Doc2g
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein gamma (Doc2-gamma).

PA24B_MOUSE
NC score	0.058420 (rank : 122)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	262	Target Neighborhood Hits	102	Shared Neighborhood Hits	16
SwissProt Accessions	Q4QQM1, Q80VV8, Q91W88	Gene names	Pla2g4b
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

SYT2_MOUSE
NC score	0.057539 (rank : 123)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	262	Target Neighborhood Hits	143	Shared Neighborhood Hits	21
SwissProt Accessions	P46097, Q8R0E1	Gene names	Syt2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT10_MOUSE
NC score	0.057460 (rank : 124)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	262	Target Neighborhood Hits	133	Shared Neighborhood Hits	19
SwissProt Accessions	Q9R0N4	Gene names	Syt10
Domain Architecture
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

SYT2_HUMAN
NC score	0.057425 (rank : 125)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	262	Target Neighborhood Hits	142	Shared Neighborhood Hits	21
SwissProt Accessions	Q8N9I0, Q496K5, Q8NBE5	Gene names	SYT2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT5_MOUSE
NC score	0.056599 (rank : 126)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	262	Target Neighborhood Hits	140	Shared Neighborhood Hits	19
SwissProt Accessions	Q9R0N5	Gene names	Syt5, Syt9
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV) (Synaptotagmin IX).

CUL7_HUMAN
NC score	0.055957 (rank : 127)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	262	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	Q14999, Q5T654	Gene names	CUL7, KIAA0076
Domain Architecture
Description	Cullin-7 (CUL-7).

TARA_HUMAN
NC score	0.055803 (rank : 128)	θ value	0.62314 (rank : 130)
Query Neighborhood Hits	262	Target Neighborhood Hits	1626	Shared Neighborhood Hits	122
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

SYT9_MOUSE
NC score	0.054988 (rank : 129)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	262	Target Neighborhood Hits	148	Shared Neighborhood Hits	18
SwissProt Accessions	Q9R0N9, Q8C280	Gene names	Syt9, Syt5
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX) (Synaptotagmin V).

MDC1_HUMAN
NC score	0.054966 (rank : 130)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	262	Target Neighborhood Hits	1446	Shared Neighborhood Hits	123
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MYOF_HUMAN
NC score	0.054486 (rank : 131)	θ value	5.27518 (rank : 211)
Query Neighborhood Hits	262	Target Neighborhood Hits	147	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NZM1, Q9HBU3, Q9NZM0, Q9ULL3, Q9Y4U4	Gene names	FER1L3, KIAA1207, MYOF
Domain Architecture
Description	Myoferlin (Fer-1-like protein 3).

RIMS1_HUMAN
NC score	0.054137 (rank : 132)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	262	Target Neighborhood Hits	437	Shared Neighborhood Hits	43
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

SYTL2_MOUSE
NC score	0.053967 (rank : 133)	θ value	5.27518 (rank : 219)
Query Neighborhood Hits	262	Target Neighborhood Hits	253	Shared Neighborhood Hits	29
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

SYT9_HUMAN
NC score	0.053739 (rank : 134)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	262	Target Neighborhood Hits	144	Shared Neighborhood Hits	18
SwissProt Accessions	Q86SS6	Gene names	SYT9
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX).

WBP4_HUMAN
NC score	0.052899 (rank : 135)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	262	Target Neighborhood Hits	86	Shared Neighborhood Hits	22
SwissProt Accessions	O75554	Gene names	WBP4, FBP21, FNBP21
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21).

TGON2_HUMAN
NC score	0.052621 (rank : 136)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	262	Target Neighborhood Hits	1037	Shared Neighborhood Hits	96
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

ALS2_HUMAN
NC score	0.052370 (rank : 137)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	262	Target Neighborhood Hits	121	Shared Neighborhood Hits	9
SwissProt Accessions	Q96Q42, Q8N1E0, Q96PC4, Q96Q41, Q9H973, Q9HCK9	Gene names	ALS2, KIAA1563
Domain Architecture
Description	Alsin (Amyotrophic lateral sclerosis protein 2).

SYT6_MOUSE
NC score	0.052316 (rank : 138)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	262	Target Neighborhood Hits	132	Shared Neighborhood Hits	19
SwissProt Accessions	Q9R0N8	Gene names	Syt6
Domain Architecture
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

SYT3_MOUSE
NC score	0.051582 (rank : 139)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	262	Target Neighborhood Hits	147	Shared Neighborhood Hits	19
SwissProt Accessions	O35681, P97791, Q80WV1	Gene names	Syt3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

SYTL2_HUMAN
NC score	0.051559 (rank : 140)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	262	Target Neighborhood Hits	248	Shared Neighborhood Hits	31
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

WWC3_HUMAN
NC score	0.051233 (rank : 141)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	262	Target Neighborhood Hits	193	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ULE0, Q659C1, Q9BTQ1	Gene names	WWC3, KIAA1280
Domain Architecture	No domain graphic available
Description	WWC family member 3.

DMD_HUMAN
NC score	0.051150 (rank : 142)	θ value	0.0961366 (rank : 84)
Query Neighborhood Hits	262	Target Neighborhood Hits	1135	Shared Neighborhood Hits	61
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

SYT3_HUMAN
NC score	0.051053 (rank : 143)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	262	Target Neighborhood Hits	145	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BQG1, Q8N5Z1, Q8N640	Gene names	SYT3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

SYT6_HUMAN
NC score	0.050799 (rank : 144)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	262	Target Neighborhood Hits	138	Shared Neighborhood Hits	18
SwissProt Accessions	Q5T7P8	Gene names	SYT6
Domain Architecture	No domain graphic available
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

ALS2_MOUSE
NC score	0.050586 (rank : 145)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	262	Target Neighborhood Hits	111	Shared Neighborhood Hits	8
SwissProt Accessions	Q920R0, Q8JZR1, Q9CXJ3	Gene names	Als2
Domain Architecture
Description	Alsin (Amyotrophic lateral sclerosis protein 2 homolog).

SYTL4_HUMAN
NC score	0.050452 (rank : 146)	θ value	0.0193708 (rank : 77)
Query Neighborhood Hits	262	Target Neighborhood Hits	138	Shared Neighborhood Hits	19
SwissProt Accessions	Q96C24, Q5H9J3, Q5JPG8, Q8N9P4, Q9H4R0, Q9H4R1	Gene names	SYTL4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

BAIP3_MOUSE
NC score	0.050323 (rank : 147)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	262	Target Neighborhood Hits	112	Shared Neighborhood Hits	18
SwissProt Accessions	Q80TT2, Q6RUT4	Gene names	Baiap3, Gm937, Kiaa0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

SRRM2_MOUSE
NC score	0.049385 (rank : 148)	θ value	2.36792 (rank : 174)
Query Neighborhood Hits	262	Target Neighborhood Hits	1470	Shared Neighborhood Hits	114
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

MUC13_HUMAN
NC score	0.048843 (rank : 149)	θ value	0.0330416 (rank : 79)
Query Neighborhood Hits	262	Target Neighborhood Hits	164	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

SRRM2_HUMAN
NC score	0.048833 (rank : 150)	θ value	0.365318 (rank : 112)
Query Neighborhood Hits	262	Target Neighborhood Hits	1296	Shared Neighborhood Hits	95
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SELPL_MOUSE
NC score	0.048703 (rank : 151)	θ value	1.81305 (rank : 157)
Query Neighborhood Hits	262	Target Neighborhood Hits	588	Shared Neighborhood Hits	82
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

NU214_HUMAN
NC score	0.048577 (rank : 152)	θ value	6.88961 (rank : 233)
Query Neighborhood Hits	262	Target Neighborhood Hits	657	Shared Neighborhood Hits	71
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

SYTL4_MOUSE
NC score	0.047981 (rank : 153)	θ value	0.0148317 (rank : 76)
Query Neighborhood Hits	262	Target Neighborhood Hits	137	Shared Neighborhood Hits	18
SwissProt Accessions	Q9R0Q1, Q8R321, Q9R0Q0	Gene names	Sytl4, Slp4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

DMD_MOUSE
NC score	0.047283 (rank : 154)	θ value	0.0961366 (rank : 85)
Query Neighborhood Hits	262	Target Neighborhood Hits	1111	Shared Neighborhood Hits	61
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

LAD1_MOUSE
NC score	0.046861 (rank : 155)	θ value	0.00509761 (rank : 67)
Query Neighborhood Hits	262	Target Neighborhood Hits	391	Shared Neighborhood Hits	46
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

PODXL_HUMAN
NC score	0.043588 (rank : 156)	θ value	1.38821 (rank : 150)
Query Neighborhood Hits	262	Target Neighborhood Hits	191	Shared Neighborhood Hits	38
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

MUC7_HUMAN
NC score	0.043404 (rank : 157)	θ value	0.47712 (rank : 118)
Query Neighborhood Hits	262	Target Neighborhood Hits	538	Shared Neighborhood Hits	64
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

UTRO_HUMAN
NC score	0.042849 (rank : 158)	θ value	0.21417 (rank : 100)
Query Neighborhood Hits	262	Target Neighborhood Hits	960	Shared Neighborhood Hits	51
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

RD23B_MOUSE
NC score	0.040713 (rank : 159)	θ value	0.0113563 (rank : 72)
Query Neighborhood Hits	262	Target Neighborhood Hits	189	Shared Neighborhood Hits	21
SwissProt Accessions	P54728	Gene names	Rad23b, Mhr23b
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (mHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

IWS1_HUMAN
NC score	0.037821 (rank : 160)	θ value	0.0252991 (rank : 78)
Query Neighborhood Hits	262	Target Neighborhood Hits	1241	Shared Neighborhood Hits	78
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MDC1_MOUSE
NC score	0.037366 (rank : 161)	θ value	8.99809 (rank : 249)
Query Neighborhood Hits	262	Target Neighborhood Hits	998	Shared Neighborhood Hits	105
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

NELFA_MOUSE
NC score	0.035722 (rank : 162)	θ value	0.0736092 (rank : 82)
Query Neighborhood Hits	262	Target Neighborhood Hits	195	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

PO121_HUMAN
NC score	0.034947 (rank : 163)	θ value	0.0148317 (rank : 73)
Query Neighborhood Hits	262	Target Neighborhood Hits	344	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

IWS1_MOUSE
NC score	0.034852 (rank : 164)	θ value	3.0926 (rank : 183)
Query Neighborhood Hits	262	Target Neighborhood Hits	1258	Shared Neighborhood Hits	78
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PAPOA_HUMAN
NC score	0.033399 (rank : 165)	θ value	0.000602161 (rank : 60)
Query Neighborhood Hits	262	Target Neighborhood Hits	75	Shared Neighborhood Hits	13
SwissProt Accessions	P51003, Q86SX4, Q86TV0, Q8IYF5, Q9BVU2	Gene names	PAPOLA, PAP
Domain Architecture	No domain graphic available
Description	Poly(A) polymerase alpha (EC 2.7.7.19) (PAP) (Polynucleotide adenylyltransferase alpha).

RD23B_HUMAN
NC score	0.033002 (rank : 166)	θ value	0.163984 (rank : 94)
Query Neighborhood Hits	262	Target Neighborhood Hits	115	Shared Neighborhood Hits	14
SwissProt Accessions	P54727, Q8WUB0	Gene names	RAD23B
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (hHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

MUC2_HUMAN
NC score	0.032174 (rank : 167)	θ value	0.279714 (rank : 103)
Query Neighborhood Hits	262	Target Neighborhood Hits	906	Shared Neighborhood Hits	61
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

PARM1_MOUSE
NC score	0.031745 (rank : 168)	θ value	2.36792 (rank : 172)
Query Neighborhood Hits	262	Target Neighborhood Hits	140	Shared Neighborhood Hits	33
SwissProt Accessions	Q923D3, Q3TTV0, Q3UFU4	Gene names
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

DMP1_HUMAN
NC score	0.031677 (rank : 169)	θ value	0.47712 (rank : 114)
Query Neighborhood Hits	262	Target Neighborhood Hits	491	Shared Neighborhood Hits	26
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

SRRM1_HUMAN
NC score	0.031447 (rank : 170)	θ value	5.27518 (rank : 217)
Query Neighborhood Hits	262	Target Neighborhood Hits	690	Shared Neighborhood Hits	47
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRRM1_MOUSE
NC score	0.031334 (rank : 171)	θ value	6.88961 (rank : 236)
Query Neighborhood Hits	262	Target Neighborhood Hits	966	Shared Neighborhood Hits	67
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

RFIP1_MOUSE
NC score	0.031268 (rank : 172)	θ value	0.125558 (rank : 89)
Query Neighborhood Hits	262	Target Neighborhood Hits	152	Shared Neighborhood Hits	16
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

CN155_HUMAN
NC score	0.031255 (rank : 173)	θ value	4.03905 (rank : 190)
Query Neighborhood Hits	262	Target Neighborhood Hits	385	Shared Neighborhood Hits	40
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

PRG4_HUMAN
NC score	0.030830 (rank : 174)	θ value	3.0926 (rank : 185)
Query Neighborhood Hits	262	Target Neighborhood Hits	764	Shared Neighborhood Hits	62
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

CK024_HUMAN
NC score	0.030393 (rank : 175)	θ value	6.88961 (rank : 225)
Query Neighborhood Hits	262	Target Neighborhood Hits	408	Shared Neighborhood Hits	61
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

RFIP1_HUMAN
NC score	0.030348 (rank : 176)	θ value	0.365318 (rank : 111)
Query Neighborhood Hits	262	Target Neighborhood Hits	236	Shared Neighborhood Hits	33
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

MUC5B_HUMAN
NC score	0.030134 (rank : 177)	θ value	0.47712 (rank : 117)
Query Neighborhood Hits	262	Target Neighborhood Hits	1020	Shared Neighborhood Hits	71
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

NCOR2_HUMAN
NC score	0.029770 (rank : 178)	θ value	0.62314 (rank : 126)
Query Neighborhood Hits	262	Target Neighborhood Hits	870	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

CBP_MOUSE
NC score	0.029744 (rank : 179)	θ value	2.36792 (rank : 166)
Query Neighborhood Hits	262	Target Neighborhood Hits	1051	Shared Neighborhood Hits	85
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CBP_HUMAN
NC score	0.029686 (rank : 180)	θ value	2.36792 (rank : 165)
Query Neighborhood Hits	262	Target Neighborhood Hits	941	Shared Neighborhood Hits	73
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

TCOF_HUMAN
NC score	0.029007 (rank : 181)	θ value	1.81305 (rank : 161)
Query Neighborhood Hits	262	Target Neighborhood Hits	543	Shared Neighborhood Hits	48
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

NELFA_HUMAN
NC score	0.028965 (rank : 182)	θ value	2.36792 (rank : 171)
Query Neighborhood Hits	262	Target Neighborhood Hits	161	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H3P2, O95392	Gene names	WHSC2, NELFA
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 protein).

DREB_MOUSE
NC score	0.028699 (rank : 183)	θ value	0.0961366 (rank : 86)
Query Neighborhood Hits	262	Target Neighborhood Hits	446	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

SET1A_HUMAN
NC score	0.028629 (rank : 184)	θ value	6.88961 (rank : 235)
Query Neighborhood Hits	262	Target Neighborhood Hits	690	Shared Neighborhood Hits	59
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

PAPOA_MOUSE
NC score	0.027969 (rank : 185)	θ value	0.21417 (rank : 99)
Query Neighborhood Hits	262	Target Neighborhood Hits	115	Shared Neighborhood Hits	22
SwissProt Accessions	Q61183, Q61208, Q61209, Q8K4X2	Gene names	Papola, Pap, Plap
Domain Architecture
Description	Poly(A) polymerase alpha (EC 2.7.7.19) (PAP) (Polynucleotide adenylyltransferase).

MKL1_HUMAN
NC score	0.027387 (rank : 186)	θ value	0.00509761 (rank : 68)
Query Neighborhood Hits	262	Target Neighborhood Hits	232	Shared Neighborhood Hits	19
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

TP53B_HUMAN
NC score	0.027234 (rank : 187)	θ value	8.99809 (rank : 259)
Query Neighborhood Hits	262	Target Neighborhood Hits	413	Shared Neighborhood Hits	40
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

BAT2_HUMAN
NC score	0.026974 (rank : 188)	θ value	0.365318 (rank : 107)
Query Neighborhood Hits	262	Target Neighborhood Hits	931	Shared Neighborhood Hits	64
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CSF1_HUMAN
NC score	0.026793 (rank : 189)	θ value	2.36792 (rank : 168)
Query Neighborhood Hits	262	Target Neighborhood Hits	258	Shared Neighborhood Hits	36
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

DSPP_HUMAN
NC score	0.026738 (rank : 190)	θ value	4.03905 (rank : 192)
Query Neighborhood Hits	262	Target Neighborhood Hits	645	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

TARA_MOUSE
NC score	0.026641 (rank : 191)	θ value	2.36792 (rank : 175)
Query Neighborhood Hits	262	Target Neighborhood Hits	1133	Shared Neighborhood Hits	80
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

K0460_MOUSE
NC score	0.026267 (rank : 192)	θ value	0.62314 (rank : 125)
Query Neighborhood Hits	262	Target Neighborhood Hits	374	Shared Neighborhood Hits	40
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

ACINU_HUMAN
NC score	0.025638 (rank : 193)	θ value	0.813845 (rank : 131)
Query Neighborhood Hits	262	Target Neighborhood Hits	828	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

TARSH_HUMAN
NC score	0.025422 (rank : 194)	θ value	4.03905 (rank : 203)
Query Neighborhood Hits	262	Target Neighborhood Hits	768	Shared Neighborhood Hits	66
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

ENL_HUMAN
NC score	0.025340 (rank : 195)	θ value	1.06291 (rank : 140)
Query Neighborhood Hits	262	Target Neighborhood Hits	305	Shared Neighborhood Hits	31
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

MLH3_HUMAN
NC score	0.024995 (rank : 196)	θ value	1.06291 (rank : 142)
Query Neighborhood Hits	262	Target Neighborhood Hits	42	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UHC1, P49751, Q56DK9, Q9P292, Q9UHC0	Gene names	MLH3
Domain Architecture
Description	DNA mismatch repair protein Mlh3 (MutL protein homolog 3).

E2F4_HUMAN
NC score	0.024636 (rank : 197)	θ value	8.99809 (rank : 244)
Query Neighborhood Hits	262	Target Neighborhood Hits	188	Shared Neighborhood Hits	27
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).

GP112_HUMAN
NC score	0.024053 (rank : 198)	θ value	6.88961 (rank : 229)
Query Neighborhood Hits	262	Target Neighborhood Hits	441	Shared Neighborhood Hits	57
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

DLG7_HUMAN
NC score	0.023907 (rank : 199)	θ value	1.81305 (rank : 152)
Query Neighborhood Hits	262	Target Neighborhood Hits	53	Shared Neighborhood Hits	7
SwissProt Accessions	Q15398, Q8NG58	Gene names	DLG7, KIAA0008
Domain Architecture
Description	Discs large homolog 7 (Hepatoma up-regulated protein) (HURP).

SYNJ1_MOUSE
NC score	0.023572 (rank : 200)	θ value	4.03905 (rank : 202)
Query Neighborhood Hits	262	Target Neighborhood Hits	516	Shared Neighborhood Hits	57
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

ATN1_HUMAN
NC score	0.023279 (rank : 201)	θ value	1.81305 (rank : 151)
Query Neighborhood Hits	262	Target Neighborhood Hits	676	Shared Neighborhood Hits	56
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

BPTF_HUMAN
NC score	0.023215 (rank : 202)	θ value	0.813845 (rank : 133)
Query Neighborhood Hits	262	Target Neighborhood Hits	786	Shared Neighborhood Hits	55
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

MILK1_MOUSE
NC score	0.023033 (rank : 203)	θ value	1.81305 (rank : 154)
Query Neighborhood Hits	262	Target Neighborhood Hits	788	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

CEND1_HUMAN
NC score	0.022717 (rank : 204)	θ value	0.00175202 (rank : 64)
Query Neighborhood Hits	262	Target Neighborhood Hits	284	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

DLG7_MOUSE
NC score	0.022647 (rank : 205)	θ value	1.81305 (rank : 153)
Query Neighborhood Hits	262	Target Neighborhood Hits	84	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K4R9, Q6ZQL3, Q80VS7, Q8BUC8, Q8BZ79	Gene names	Dlg7, Kiaa0008
Domain Architecture	No domain graphic available
Description	Discs large homolog 7 (Hepatoma up-regulated protein homolog) (HURP).

DSPP_MOUSE
NC score	0.022612 (rank : 206)	θ value	0.62314 (rank : 122)
Query Neighborhood Hits	262	Target Neighborhood Hits	491	Shared Neighborhood Hits	35
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

SYNJ1_HUMAN
NC score	0.022273 (rank : 207)	θ value	0.125558 (rank : 90)
Query Neighborhood Hits	262	Target Neighborhood Hits	498	Shared Neighborhood Hits	47
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

PRG4_MOUSE
NC score	0.021903 (rank : 208)	θ value	4.03905 (rank : 199)
Query Neighborhood Hits	262	Target Neighborhood Hits	624	Shared Neighborhood Hits	55
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

CNOT3_MOUSE
NC score	0.021673 (rank : 209)	θ value	0.62314 (rank : 121)
Query Neighborhood Hits	262	Target Neighborhood Hits	504	Shared Neighborhood Hits	37
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

SDC3_HUMAN
NC score	0.021665 (rank : 210)	θ value	1.06291 (rank : 143)
Query Neighborhood Hits	262	Target Neighborhood Hits	103	Shared Neighborhood Hits	22
SwissProt Accessions	O75056, Q5T1Z6, Q5T1Z7, Q96CT3, Q96PR8	Gene names	SDC3, KIAA0468
Domain Architecture
Description	Syndecan-3 (SYND3).

E2F5_HUMAN
NC score	0.020942 (rank : 211)	θ value	0.0961366 (rank : 87)
Query Neighborhood Hits	262	Target Neighborhood Hits	55	Shared Neighborhood Hits	8
SwissProt Accessions	Q15329, Q16601, Q92756	Gene names	E2F5
Domain Architecture
Description	Transcription factor E2F5 (E2F-5).

MINT_HUMAN
NC score	0.020754 (rank : 212)	θ value	6.88961 (rank : 231)
Query Neighborhood Hits	262	Target Neighborhood Hits	1291	Shared Neighborhood Hits	95
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

DCR1C_MOUSE
NC score	0.020578 (rank : 213)	θ value	0.163984 (rank : 93)
Query Neighborhood Hits	262	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K4J0, Q8BG72, Q8BTT1	Gene names	Dclre1c, Art, Snm1l
Domain Architecture	No domain graphic available
Description	Artemis protein (EC 3.1.-.-) (DNA cross-link repair 1C protein) (mArt protein) (SNM1-like protein).

LIMA1_MOUSE
NC score	0.020516 (rank : 214)	θ value	0.125558 (rank : 88)
Query Neighborhood Hits	262	Target Neighborhood Hits	298	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ERG0, Q9ERG1	Gene names	Lima1, D15Ertd366e, Eplin
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm) (mEPLIN).

K1958_HUMAN
NC score	0.020241 (rank : 215)	θ value	1.06291 (rank : 141)
Query Neighborhood Hits	262	Target Neighborhood Hits	76	Shared Neighborhood Hits	16
SwissProt Accessions	Q8N8K9, Q5T252, Q8TF43, Q96N02	Gene names	KIAA1958
Domain Architecture	No domain graphic available
Description	Protein KIAA1958.

MINT_MOUSE
NC score	0.019976 (rank : 216)	θ value	5.27518 (rank : 210)
Query Neighborhood Hits	262	Target Neighborhood Hits	1514	Shared Neighborhood Hits	96
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

AKAP2_HUMAN
NC score	0.019918 (rank : 217)	θ value	1.38821 (rank : 145)
Query Neighborhood Hits	262	Target Neighborhood Hits	507	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

MILK1_HUMAN
NC score	0.019716 (rank : 218)	θ value	8.99809 (rank : 250)
Query Neighborhood Hits	262	Target Neighborhood Hits	427	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

FEZ1_HUMAN
NC score	0.019685 (rank : 219)	θ value	0.279714 (rank : 102)
Query Neighborhood Hits	262	Target Neighborhood Hits	120	Shared Neighborhood Hits	7
SwissProt Accessions	Q99689, O00679, O00728, Q6IBI7	Gene names	FEZ1
Domain Architecture	No domain graphic available
Description	Fasciculation and elongation protein zeta 1 (Zygin-1) (Zygin I).

PF21B_MOUSE
NC score	0.019656 (rank : 220)	θ value	1.81305 (rank : 156)
Query Neighborhood Hits	262	Target Neighborhood Hits	278	Shared Neighborhood Hits	42
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

K0226_HUMAN
NC score	0.019588 (rank : 221)	θ value	0.365318 (rank : 109)
Query Neighborhood Hits	262	Target Neighborhood Hits	92	Shared Neighborhood Hits	11
SwissProt Accessions	Q92622	Gene names	KIAA0226
Domain Architecture	No domain graphic available
Description	Protein KIAA0226.

GNAS1_MOUSE
NC score	0.019095 (rank : 222)	θ value	0.0113563 (rank : 71)
Query Neighborhood Hits	262	Target Neighborhood Hits	651	Shared Neighborhood Hits	49
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

ADRM1_MOUSE
NC score	0.018714 (rank : 223)	θ value	4.03905 (rank : 188)
Query Neighborhood Hits	262	Target Neighborhood Hits	84	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JKV1	Gene names	Adrm1, Gp110
Domain Architecture
Description	Adhesion-regulating molecule 1 precursor (110 kDa cell membrane glycoprotein) (Gp110) (ARM-1).

NUP62_HUMAN
NC score	0.018467 (rank : 224)	θ value	0.813845 (rank : 135)
Query Neighborhood Hits	262	Target Neighborhood Hits	195	Shared Neighborhood Hits	14
SwissProt Accessions	P37198, Q503A4, Q96C43, Q9NSL1	Gene names	NUP62
Domain Architecture
Description	Nuclear pore glycoprotein p62 (62 kDa nucleoporin).

ZCH10_MOUSE
NC score	0.018351 (rank : 225)	θ value	5.27518 (rank : 221)
Query Neighborhood Hits	262	Target Neighborhood Hits	133	Shared Neighborhood Hits	13
SwissProt Accessions	Q9CX48	Gene names	Zcchc10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

HCFC1_HUMAN
NC score	0.018337 (rank : 226)	θ value	3.0926 (rank : 181)
Query Neighborhood Hits	262	Target Neighborhood Hits	331	Shared Neighborhood Hits	41
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

MLL3_HUMAN
NC score	0.018170 (rank : 227)	θ value	8.99809 (rank : 251)
Query Neighborhood Hits	262	Target Neighborhood Hits	1644	Shared Neighborhood Hits	100
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MUCDL_HUMAN
NC score	0.017999 (rank : 228)	θ value	4.03905 (rank : 197)
Query Neighborhood Hits	262	Target Neighborhood Hits	777	Shared Neighborhood Hits	56
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

TM108_MOUSE
NC score	0.017402 (rank : 229)	θ value	8.99809 (rank : 258)
Query Neighborhood Hits	262	Target Neighborhood Hits	336	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

CE025_HUMAN
NC score	0.017367 (rank : 230)	θ value	2.36792 (rank : 167)
Query Neighborhood Hits	262	Target Neighborhood Hits	114	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NDZ2, Q6NXN8, Q6ZTU4, Q8IZ15	Gene names	C5orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C5orf25.

T240L_HUMAN
NC score	0.017208 (rank : 231)	θ value	1.06291 (rank : 144)
Query Neighborhood Hits	262	Target Neighborhood Hits	132	Shared Neighborhood Hits	16
SwissProt Accessions	Q71F56, Q68DN4, Q9H8C0, Q9NSY9, Q9UFD8, Q9UPX5	Gene names	THRAP2, KIAA1025, PROSIT240, TRAP240L
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

ADRM1_HUMAN
NC score	0.017104 (rank : 232)	θ value	4.03905 (rank : 187)
Query Neighborhood Hits	262	Target Neighborhood Hits	81	Shared Neighborhood Hits	10
SwissProt Accessions	Q16186, Q9H1P2	Gene names	ADRM1, GP110
Domain Architecture
Description	Adhesion-regulating molecule 1 precursor (110 kDa cell membrane glycoprotein) (Gp110).

OVGP1_HUMAN
NC score	0.017047 (rank : 233)	θ value	0.0736092 (rank : 83)
Query Neighborhood Hits	262	Target Neighborhood Hits	48	Shared Neighborhood Hits	13
SwissProt Accessions	Q12889, Q15841	Gene names	OVGP1, MUC9, OGP
Domain Architecture
Description	Oviduct-specific glycoprotein precursor (Oviductal glycoprotein) (Oviductin) (Estrogen-dependent oviduct protein) (Mucin 9).

AKAP6_HUMAN
NC score	0.016664 (rank : 234)	θ value	2.36792 (rank : 162)
Query Neighborhood Hits	262	Target Neighborhood Hits	263	Shared Neighborhood Hits	22
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

TJAP1_HUMAN
NC score	0.016090 (rank : 235)	θ value	4.03905 (rank : 204)
Query Neighborhood Hits	262	Target Neighborhood Hits	214	Shared Neighborhood Hits	14
SwissProt Accessions	Q5JTD0, Q5JTD1, Q5JWW1, Q68DB2, Q6P2P3, Q9H7V7	Gene names	TJAP1, PILT, TJP4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

ZAN_MOUSE
NC score	0.016030 (rank : 236)	θ value	0.0563607 (rank : 81)
Query Neighborhood Hits	262	Target Neighborhood Hits	808	Shared Neighborhood Hits	30
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

RAI1_HUMAN
NC score	0.015846 (rank : 237)	θ value	4.03905 (rank : 200)
Query Neighborhood Hits	262	Target Neighborhood Hits	360	Shared Neighborhood Hits	36
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

GR65_MOUSE
NC score	0.015833 (rank : 238)	θ value	0.47712 (rank : 115)
Query Neighborhood Hits	262	Target Neighborhood Hits	54	Shared Neighborhood Hits	4
SwissProt Accessions	Q91X51, Q9D3L9	Gene names	Gorasp1
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 1 (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) (Golgi peripheral membrane protein p65).

SPESP_HUMAN
NC score	0.015713 (rank : 239)	θ value	2.36792 (rank : 173)
Query Neighborhood Hits	262	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q6UW49, Q8NG22, Q8WVH8	Gene names	SPESP1
Domain Architecture	No domain graphic available
Description	Sperm equatorial segment protein 1 precursor (SP-ESP) (Equatorial segment protein) (ESP) (Glycosylated 38 kDa sperm protein C-7/8).

TR240_HUMAN
NC score	0.015607 (rank : 240)	θ value	2.36792 (rank : 176)
Query Neighborhood Hits	262	Target Neighborhood Hits	99	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UHV7, O60334	Gene names	THRAP1, ARC250, KIAA0593, TRAP240
Domain Architecture
Description	Thyroid hormone receptor-associated protein complex 240 kDa component (Trap240) (Thyroid hormone receptor-associated protein 1) (Vitamin D3 receptor-interacting protein complex component DRIP250) (DRIP 250) (Activator-recruited cofactor 250 kDa component) (ARC250).

CAF1A_HUMAN
NC score	0.015505 (rank : 241)	θ value	1.06291 (rank : 138)
Query Neighborhood Hits	262	Target Neighborhood Hits	750	Shared Neighborhood Hits	30
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

GSCR1_HUMAN
NC score	0.015027 (rank : 242)	θ value	8.99809 (rank : 246)
Query Neighborhood Hits	262	Target Neighborhood Hits	674	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

PI5PA_MOUSE
NC score	0.013993 (rank : 243)	θ value	5.27518 (rank : 214)
Query Neighborhood Hits	262	Target Neighborhood Hits	331	Shared Neighborhood Hits	31
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

BIN1_MOUSE
NC score	0.013174 (rank : 244)	θ value	4.03905 (rank : 189)
Query Neighborhood Hits	262	Target Neighborhood Hits	283	Shared Neighborhood Hits	20
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

E2F5_MOUSE
NC score	0.013165 (rank : 245)	θ value	6.88961 (rank : 227)
Query Neighborhood Hits	262	Target Neighborhood Hits	43	Shared Neighborhood Hits	6
SwissProt Accessions	Q61502	Gene names	E2f5
Domain Architecture
Description	Transcription factor E2F5 (E2F-5).

SETX_HUMAN
NC score	0.012602 (rank : 246)	θ value	4.03905 (rank : 201)
Query Neighborhood Hits	262	Target Neighborhood Hits	368	Shared Neighborhood Hits	29
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

PGCB_HUMAN
NC score	0.012253 (rank : 247)	θ value	0.279714 (rank : 104)
Query Neighborhood Hits	262	Target Neighborhood Hits	478	Shared Neighborhood Hits	26
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

CAC1A_MOUSE
NC score	0.012218 (rank : 248)	θ value	2.36792 (rank : 164)
Query Neighborhood Hits	262	Target Neighborhood Hits	267	Shared Neighborhood Hits	27
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

STON2_MOUSE
NC score	0.012114 (rank : 249)	θ value	1.81305 (rank : 160)
Query Neighborhood Hits	262	Target Neighborhood Hits	75	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BZ60	Gene names	Ston2, Stn2, Stnb
Domain Architecture
Description	Stonin-2 (Stoned B).

PYGO2_HUMAN
NC score	0.011920 (rank : 250)	θ value	5.27518 (rank : 216)
Query Neighborhood Hits	262	Target Neighborhood Hits	189	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

RAE1_HUMAN
NC score	0.011779 (rank : 251)	θ value	0.62314 (rank : 129)
Query Neighborhood Hits	262	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	P24386, O43732	Gene names	CHM, REP1, TCD
Domain Architecture
Description	Rab proteins geranylgeranyltransferase component A 1 (Rab escort protein 1) (REP-1) (Choroideraemia protein) (TCD protein).

IF4G3_HUMAN
NC score	0.011741 (rank : 252)	θ value	0.62314 (rank : 124)
Query Neighborhood Hits	262	Target Neighborhood Hits	247	Shared Neighborhood Hits	13
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

XE7_HUMAN
NC score	0.011703 (rank : 253)	θ value	0.813845 (rank : 136)
Query Neighborhood Hits	262	Target Neighborhood Hits	738	Shared Neighborhood Hits	26
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

DIDO1_HUMAN
NC score	0.011205 (rank : 254)	θ value	8.99809 (rank : 242)
Query Neighborhood Hits	262	Target Neighborhood Hits	960	Shared Neighborhood Hits	58
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

JIP3_HUMAN
NC score	0.011115 (rank : 255)	θ value	4.03905 (rank : 195)
Query Neighborhood Hits	262	Target Neighborhood Hits	1039	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

YETS2_HUMAN
NC score	0.011091 (rank : 256)	θ value	8.99809 (rank : 261)
Query Neighborhood Hits	262	Target Neighborhood Hits	212	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ULM3, Q641P6, Q9NW96	Gene names	YEATS2, KIAA1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

CTTB2_HUMAN
NC score	0.010877 (rank : 257)	θ value	0.163984 (rank : 92)
Query Neighborhood Hits	262	Target Neighborhood Hits	1061	Shared Neighborhood Hits	40
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

OPHN1_MOUSE
NC score	0.010665 (rank : 258)	θ value	5.27518 (rank : 212)
Query Neighborhood Hits	262	Target Neighborhood Hits	174	Shared Neighborhood Hits	7
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

SOX30_HUMAN
NC score	0.010621 (rank : 259)	θ value	1.81305 (rank : 158)
Query Neighborhood Hits	262	Target Neighborhood Hits	305	Shared Neighborhood Hits	33
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

PEX14_HUMAN
NC score	0.010482 (rank : 260)	θ value	4.03905 (rank : 198)
Query Neighborhood Hits	262	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	O75381, Q8WX51	Gene names	PEX14
Domain Architecture
Description	Peroxisomal membrane protein PEX14 (Peroxin-14) (Peroxisomal membrane anchor protein PEX14) (PTS1 receptor docking protein).

UBXD2_HUMAN
NC score	0.009831 (rank : 261)	θ value	4.03905 (rank : 205)
Query Neighborhood Hits	262	Target Neighborhood Hits	241	Shared Neighborhood Hits	15
SwissProt Accessions	Q92575, Q8IYM5	Gene names	UBXD2, KIAA0242, UBXDC1
Domain Architecture
Description	UBX domain-containing protein 2.

TJAP1_MOUSE
NC score	0.009737 (rank : 262)	θ value	6.88961 (rank : 238)
Query Neighborhood Hits	262	Target Neighborhood Hits	295	Shared Neighborhood Hits	15
SwissProt Accessions	Q9DCD5, Q8CFL7, Q8R5I2	Gene names	Tjap1, Pilt, Tjp4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

AF10_HUMAN
NC score	0.009437 (rank : 263)	θ value	0.62314 (rank : 120)
Query Neighborhood Hits	262	Target Neighborhood Hits	198	Shared Neighborhood Hits	12
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

AP3B1_HUMAN
NC score	0.008950 (rank : 264)	θ value	2.36792 (rank : 163)
Query Neighborhood Hits	262	Target Neighborhood Hits	283	Shared Neighborhood Hits	19
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

PYGO1_HUMAN
NC score	0.008921 (rank : 265)	θ value	8.99809 (rank : 255)
Query Neighborhood Hits	262	Target Neighborhood Hits	90	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y3Y4	Gene names	PYGO1
Domain Architecture
Description	Pygopus homolog 1.

PLXB1_HUMAN
NC score	0.008603 (rank : 266)	θ value	0.62314 (rank : 128)
Query Neighborhood Hits	262	Target Neighborhood Hits	360	Shared Neighborhood Hits	37
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

RTN1_HUMAN
NC score	0.008467 (rank : 267)	θ value	6.88961 (rank : 234)
Query Neighborhood Hits	262	Target Neighborhood Hits	173	Shared Neighborhood Hits	16
SwissProt Accessions	Q16799, Q16800, Q16801	Gene names	RTN1, NSP
Domain Architecture
Description	Reticulon-1 (Neuroendocrine-specific protein).

CB017_MOUSE
NC score	0.008404 (rank : 268)	θ value	5.27518 (rank : 207)
Query Neighborhood Hits	262	Target Neighborhood Hits	63	Shared Neighborhood Hits	6
SwissProt Accessions	Q6NS82, Q3TA48, Q8BSD3, Q8CHY1, Q8R0Q3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf17 homolog.

EDAD_MOUSE
NC score	0.008093 (rank : 269)	θ value	6.88961 (rank : 228)
Query Neighborhood Hits	262	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VHX2	Gene names	Edaradd, Cr
Domain Architecture	No domain graphic available
Description	Ectodysplasin A receptor-associated adapter protein (EDAR-associated death domain protein) (Crinkled protein).

DGLA_MOUSE
NC score	0.007924 (rank : 270)	θ value	3.0926 (rank : 180)
Query Neighborhood Hits	262	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	Q6WQJ1, Q6ZQ76	Gene names	Nsddr, Kiaa0659
Domain Architecture	No domain graphic available
Description	Sn1-specific diacylglycerol lipase alpha (EC 3.1.1.-) (DGL-alpha) (Neural stem cell-derived dendrite regulator).

ORC3_HUMAN
NC score	0.007882 (rank : 271)	θ value	8.99809 (rank : 254)
Query Neighborhood Hits	262	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UBD5, Q13565, Q6IUY7, Q9UG44, Q9UNT6	Gene names	ORC3L, LATHEO
Domain Architecture
Description	Origin recognition complex subunit 3 (Origin recognition complex subunit Latheo).

CAC1A_HUMAN
NC score	0.007761 (rank : 272)	θ value	3.0926 (rank : 177)
Query Neighborhood Hits	262	Target Neighborhood Hits	387	Shared Neighborhood Hits	29
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CSPG2_HUMAN
NC score	0.007679 (rank : 273)	θ value	4.03905 (rank : 191)
Query Neighborhood Hits	262	Target Neighborhood Hits	681	Shared Neighborhood Hits	44
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

PGCB_MOUSE
NC score	0.007643 (rank : 274)	θ value	3.0926 (rank : 184)
Query Neighborhood Hits	262	Target Neighborhood Hits	459	Shared Neighborhood Hits	16
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

TACC2_MOUSE
NC score	0.007571 (rank : 275)	θ value	6.88961 (rank : 237)
Query Neighborhood Hits	262	Target Neighborhood Hits	774	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

DYNA_HUMAN
NC score	0.007471 (rank : 276)	θ value	1.06291 (rank : 139)
Query Neighborhood Hits	262	Target Neighborhood Hits	1194	Shared Neighborhood Hits	37
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

CAC1B_HUMAN
NC score	0.007361 (rank : 277)	θ value	6.88961 (rank : 224)
Query Neighborhood Hits	262	Target Neighborhood Hits	257	Shared Neighborhood Hits	19
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

TRBP2_MOUSE
NC score	0.007085 (rank : 278)	θ value	6.88961 (rank : 239)
Query Neighborhood Hits	262	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	P97473	Gene names	Tarbp2, Prbp
Domain Architecture
Description	TAR RNA-binding protein 2 (Protamine-1 RNA-binding protein) (PRM-1 RNA-binding protein).

GPR64_HUMAN
NC score	0.006941 (rank : 279)	θ value	0.62314 (rank : 123)
Query Neighborhood Hits	262	Target Neighborhood Hits	207	Shared Neighborhood Hits	16
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

TRBP2_HUMAN
NC score	0.006458 (rank : 280)	θ value	8.99809 (rank : 260)
Query Neighborhood Hits	262	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q15633, Q12878	Gene names	TARBP2, TRBP
Domain Architecture
Description	TAR RNA-binding protein 2 (Trans-activation-responsive RNA-binding protein).

REST_HUMAN
NC score	0.006299 (rank : 281)	θ value	0.365318 (rank : 110)
Query Neighborhood Hits	262	Target Neighborhood Hits	1605	Shared Neighborhood Hits	49
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

ITIH1_HUMAN
NC score	0.006192 (rank : 282)	θ value	2.36792 (rank : 169)
Query Neighborhood Hits	262	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	P19827, P78455, Q01746	Gene names	ITIH1, IGHEP1
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H1 precursor (ITI heavy chain H1) (Inter-alpha-inhibitor heavy chain 1) (Inter-alpha-trypsin inhibitor complex component III) (Serum-derived hyaluronan-associated protein) (SHAP).

CFAH_MOUSE
NC score	0.005901 (rank : 283)	θ value	1.38821 (rank : 147)
Query Neighborhood Hits	262	Target Neighborhood Hits	112	Shared Neighborhood Hits	6
SwissProt Accessions	P06909	Gene names	Cfh, Hf1
Domain Architecture
Description	Complement factor H precursor (Protein beta-1-H).

DYNA_MOUSE
NC score	0.005701 (rank : 284)	θ value	6.88961 (rank : 226)
Query Neighborhood Hits	262	Target Neighborhood Hits	1084	Shared Neighborhood Hits	33
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

SUSD4_MOUSE
NC score	0.005700 (rank : 285)	θ value	5.27518 (rank : 218)
Query Neighborhood Hits	262	Target Neighborhood Hits	122	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BH32, Q8VC43	Gene names	Susd4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

LNK_HUMAN
NC score	0.005347 (rank : 286)	θ value	5.27518 (rank : 209)
Query Neighborhood Hits	262	Target Neighborhood Hits	151	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UQQ2, O95184	Gene names	LNK
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

COIA1_HUMAN
NC score	0.005149 (rank : 287)	θ value	3.0926 (rank : 179)
Query Neighborhood Hits	262	Target Neighborhood Hits	447	Shared Neighborhood Hits	25
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

CHD9_MOUSE
NC score	0.004931 (rank : 288)	θ value	3.0926 (rank : 178)
Query Neighborhood Hits	262	Target Neighborhood Hits	427	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

NP1L3_MOUSE
NC score	0.004815 (rank : 289)	θ value	8.99809 (rank : 253)
Query Neighborhood Hits	262	Target Neighborhood Hits	233	Shared Neighborhood Hits	15
SwissProt Accessions	Q794H2, O54802	Gene names	Nap1l3, Mb20
Domain Architecture	No domain graphic available
Description	Nucleosome assembly protein 1-like 3 (Brain-specific protein MB20).

UBP28_MOUSE
NC score	0.004813 (rank : 290)	θ value	5.27518 (rank : 220)
Query Neighborhood Hits	262	Target Neighborhood Hits	178	Shared Neighborhood Hits	12
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

NCA11_MOUSE
NC score	0.004772 (rank : 291)	θ value	1.38821 (rank : 149)
Query Neighborhood Hits	262	Target Neighborhood Hits	661	Shared Neighborhood Hits	36
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

NFAT5_HUMAN
NC score	0.004353 (rank : 292)	θ value	6.88961 (rank : 232)
Query Neighborhood Hits	262	Target Neighborhood Hits	217	Shared Neighborhood Hits	12
SwissProt Accessions	O94916, O95693, Q9UN18	Gene names	NFAT5, KIAA0827, TONEBP
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T-cell transcription factor NFAT5) (NF-AT5) (Tonicity-responsive enhancer-binding protein) (TonE- binding protein) (TonEBP).

EMAL4_HUMAN
NC score	0.004326 (rank : 293)	θ value	4.03905 (rank : 193)
Query Neighborhood Hits	262	Target Neighborhood Hits	306	Shared Neighborhood Hits	13
SwissProt Accessions	Q9HC35	Gene names	EML4, C2orf2, EMAPL4
Domain Architecture
Description	Echinoderm microtubule-associated protein-like 4 (EMAP-4) (Restrictedly overexpressed proliferation-associated protein) (Ropp 120).

SCN7A_HUMAN
NC score	0.004304 (rank : 294)	θ value	8.99809 (rank : 256)
Query Neighborhood Hits	262	Target Neighborhood Hits	135	Shared Neighborhood Hits	9
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

CHD4_MOUSE
NC score	0.004240 (rank : 295)	θ value	8.99809 (rank : 241)
Query Neighborhood Hits	262	Target Neighborhood Hits	408	Shared Neighborhood Hits	25
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

GASP1_MOUSE
NC score	0.004148 (rank : 296)	θ value	8.99809 (rank : 245)
Query Neighborhood Hits	262	Target Neighborhood Hits	169	Shared Neighborhood Hits	15
SwissProt Accessions	Q5U4C1, Q8BKR8, Q8BUN4, Q8BYK9, Q8CHF4, Q8R095	Gene names	Gprasp1, Kiaa0443
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 1 (GASP-1).

HXA3_MOUSE
NC score	0.003372 (rank : 297)	θ value	0.47712 (rank : 116)
Query Neighborhood Hits	262	Target Neighborhood Hits	558	Shared Neighborhood Hits	26
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

HXB5_MOUSE
NC score	0.002865 (rank : 298)	θ value	6.88961 (rank : 230)
Query Neighborhood Hits	262	Target Neighborhood Hits	337	Shared Neighborhood Hits	13
SwissProt Accessions	P09079, Q3ZAY8	Gene names	Hoxb5, Hox-2.1, Hoxb-5
Domain Architecture
Description	Homeobox protein Hox-B5 (Hox-2.1) (MU-1) (H24.1).

IRF2_HUMAN
NC score	0.002735 (rank : 299)	θ value	8.99809 (rank : 248)
Query Neighborhood Hits	262	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	P14316, Q96B99	Gene names	IRF2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).

ATS12_MOUSE
NC score	0.002315 (rank : 300)	θ value	0.813845 (rank : 132)
Query Neighborhood Hits	262	Target Neighborhood Hits	220	Shared Neighborhood Hits	3
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

SPEG_MOUSE
NC score	0.002239 (rank : 301)	θ value	0.0563607 (rank : 80)
Query Neighborhood Hits	262	Target Neighborhood Hits	1959	Shared Neighborhood Hits	80
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

HXB5_HUMAN
NC score	0.001743 (rank : 302)	θ value	3.0926 (rank : 182)
Query Neighborhood Hits	262	Target Neighborhood Hits	332	Shared Neighborhood Hits	11
SwissProt Accessions	P09067, P09069	Gene names	HOXB5, HOX2A
Domain Architecture
Description	Homeobox protein Hox-B5 (Hox-2A) (HHO.C10) (HU-1).

BMX_HUMAN
NC score	0.001202 (rank : 303)	θ value	1.06291 (rank : 137)
Query Neighborhood Hits	262	Target Neighborhood Hits	942	Shared Neighborhood Hits	17
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

FREA_HUMAN
NC score	0.001049 (rank : 304)	θ value	5.27518 (rank : 208)
Query Neighborhood Hits	262	Target Neighborhood Hits	205	Shared Neighborhood Hits	16
SwissProt Accessions	O43638, Q96D28	Gene names	FKHL18, FREAC10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein).

CAF1B_HUMAN
NC score	0.000900 (rank : 305)	θ value	5.27518 (rank : 206)
Query Neighborhood Hits	262	Target Neighborhood Hits	345	Shared Neighborhood Hits	12
SwissProt Accessions	Q13112, Q99548	Gene names	CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7
Domain Architecture
Description	Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60) (M- phase phosphoprotein 7).

HA26_HUMAN
NC score	0.000013 (rank : 306)	θ value	8.99809 (rank : 247)
Query Neighborhood Hits	262	Target Neighborhood Hits	200	Shared Neighborhood Hits	3
SwissProt Accessions	P01906, O19789	Gene names	HLA-DQA2
Domain Architecture
Description	HLA class II histocompatibility antigen, DQ(6) alpha chain precursor (DX alpha chain) (HLA-DQA1).

PEG3_MOUSE
NC score	-0.000080 (rank : 307)	θ value	5.27518 (rank : 213)
Query Neighborhood Hits	262	Target Neighborhood Hits	1101	Shared Neighborhood Hits	32
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

E2AK3_HUMAN
NC score	-0.000371 (rank : 308)	θ value	8.99809 (rank : 243)
Query Neighborhood Hits	262	Target Neighborhood Hits	859	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NZJ5, O95846	Gene names	EIF2AK3, PEK, PERK
Domain Architecture
Description	Eukaryotic translation initiation factor 2-alpha kinase 3 precursor (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) (HsPEK).

WNK1_HUMAN
NC score	-0.001168 (rank : 309)	θ value	3.0926 (rank : 186)
Query Neighborhood Hits	262	Target Neighborhood Hits	1158	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

NKX28_MOUSE
NC score	-0.001686 (rank : 310)	θ value	8.99809 (rank : 252)
Query Neighborhood Hits	262	Target Neighborhood Hits	347	Shared Neighborhood Hits	5
SwissProt Accessions	O70584	Gene names	Nkx2-8, Nkx-2.9, Nkx2-9, Nkx2h
Domain Architecture
Description	Homeobox protein Nkx-2.8 (Homeobox protein NK-2 homolog H) (Homeobox protein Nkx-2.9).

ABL1_MOUSE
NC score	-0.002034 (rank : 311)	θ value	0.62314 (rank : 119)
Query Neighborhood Hits	262	Target Neighborhood Hits	1178	Shared Neighborhood Hits	34
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

HIPK3_HUMAN
NC score	-0.002246 (rank : 312)	θ value	1.38821 (rank : 148)
Query Neighborhood Hits	262	Target Neighborhood Hits	867	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H422, O14632, Q2PBG4, Q2PBG5, Q92632, Q9HAS2	Gene names	HIPK3, DYRK6, FIST3, PKY
Domain Architecture	No domain graphic available
Description	Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Homolog of protein kinase YAK1) (Fas-interacting serine/threonine-protein kinase) (FIST) (Androgen receptor-interacting nuclear protein kinase) (ANPK).

KSR1_MOUSE
NC score	-0.002766 (rank : 313)	θ value	2.36792 (rank : 170)
Query Neighborhood Hits	262	Target Neighborhood Hits	870	Shared Neighborhood Hits	15
SwissProt Accessions	Q61097, Q61648, Q78DX8	Gene names	Ksr1, Ksr
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras) (mKSR1) (Hb protein).

STK10_HUMAN
NC score	-0.003246 (rank : 314)	θ value	8.99809 (rank : 257)
Query Neighborhood Hits	262	Target Neighborhood Hits	1921	Shared Neighborhood Hits	62
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

ABL1_HUMAN
NC score	-0.003869 (rank : 315)	θ value	6.88961 (rank : 222)
Query Neighborhood Hits	262	Target Neighborhood Hits	1220	Shared Neighborhood Hits	30
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

SP4_MOUSE
NC score	-0.004991 (rank : 316)	θ value	1.81305 (rank : 159)
Query Neighborhood Hits	262	Target Neighborhood Hits	759	Shared Neighborhood Hits	12
SwissProt Accessions	Q62445	Gene names	Sp4
Domain Architecture
Description	Transcription factor Sp4.

PLK4_MOUSE
NC score	-0.005112 (rank : 317)	θ value	5.27518 (rank : 215)
Query Neighborhood Hits	262	Target Neighborhood Hits	879	Shared Neighborhood Hits	15
SwissProt Accessions	Q64702, Q6PEP6, Q78EG6, Q8R0I5, Q9CVR6, Q9CVU6	Gene names	Plk4, Sak, Stk18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine- protein kinase 18).

MTF1_HUMAN
NC score	-0.005714 (rank : 318)	θ value	4.03905 (rank : 196)
Query Neighborhood Hits	262	Target Neighborhood Hits	814	Shared Neighborhood Hits	20
SwissProt Accessions	Q14872, Q96CB1	Gene names	MTF1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

ACM4_HUMAN
NC score	-0.006045 (rank : 319)	θ value	6.88961 (rank : 223)
Query Neighborhood Hits	262	Target Neighborhood Hits	889	Shared Neighborhood Hits	4
SwissProt Accessions	P08173	Gene names	CHRM4
Domain Architecture
Description	Muscarinic acetylcholine receptor M4.

ZN406_MOUSE
NC score	-0.006381 (rank : 320)	θ value	8.99809 (rank : 262)
Query Neighborhood Hits	262	Target Neighborhood Hits	800	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TS63	Gene names	Znf406, Zfp406
Domain Architecture	No domain graphic available
Description	Zinc finger protein 406.