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Network neighborhood for query Sequence : ORC3_HUMAN

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ORC3_HUMAN
SwissProt Accessions	Q9UBD5, Q13565, Q6IUY7, Q9UG44, Q9UNT6	Gene names	ORC3L, LATHEO
Domain Architecture
Description	Origin recognition complex subunit 3 (Origin recognition complex subunit Latheo).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ORC3_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	39	Target Neighborhood Hits	39	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UBD5, Q13565, Q6IUY7, Q9UG44, Q9UNT6	Gene names	ORC3L, LATHEO
Domain Architecture
Description	Origin recognition complex subunit 3 (Origin recognition complex subunit Latheo).

ORC3_MOUSE
θ value	0 (rank : 2)	NC score	0.981236 (rank : 2)
Query Neighborhood Hits	39	Target Neighborhood Hits	37	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JK30	Gene names	Orc3l, Orc3
Domain Architecture
Description	Origin recognition complex subunit 3 (Origin recognition complex subunit Latheo).

LRSM1_HUMAN
θ value	0.365318 (rank : 3)	NC score	0.027427 (rank : 8)
Query Neighborhood Hits	39	Target Neighborhood Hits	1078	Shared Neighborhood Hits	20
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

SHLB2_HUMAN
θ value	0.365318 (rank : 4)	NC score	0.054093 (rank : 3)
Query Neighborhood Hits	39	Target Neighborhood Hits	86	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NR46, Q8WY61, Q96JH9	Gene names	SH3GLB2, KIAA1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

SHLB2_MOUSE
θ value	0.365318 (rank : 5)	NC score	0.053908 (rank : 4)
Query Neighborhood Hits	39	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R3V5, Q8K140, Q91ZI7	Gene names	Sh3glb2, Kiaa1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

CE290_HUMAN
θ value	0.813845 (rank : 6)	NC score	0.025980 (rank : 9)
Query Neighborhood Hits	39	Target Neighborhood Hits	1553	Shared Neighborhood Hits	19
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

TRPV5_HUMAN
θ value	1.38821 (rank : 7)	NC score	0.022944 (rank : 15)
Query Neighborhood Hits	39	Target Neighborhood Hits	261	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

MYH9_HUMAN
θ value	1.81305 (rank : 8)	NC score	0.019033 (rank : 22)
Query Neighborhood Hits	39	Target Neighborhood Hits	1762	Shared Neighborhood Hits	20
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

RBCC1_HUMAN
θ value	1.81305 (rank : 9)	NC score	0.023997 (rank : 12)
Query Neighborhood Hits	39	Target Neighborhood Hits	1023	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

FNBP2_HUMAN
θ value	3.0926 (rank : 10)	NC score	0.015320 (rank : 29)
Query Neighborhood Hits	39	Target Neighborhood Hits	432	Shared Neighborhood Hits	12
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

GRAP1_MOUSE
θ value	3.0926 (rank : 11)	NC score	0.021324 (rank : 17)
Query Neighborhood Hits	39	Target Neighborhood Hits	1234	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

SNX23_HUMAN
θ value	3.0926 (rank : 12)	NC score	0.024892 (rank : 10)
Query Neighborhood Hits	39	Target Neighborhood Hits	944	Shared Neighborhood Hits	18
SwissProt Accessions	Q96L93, Q5HYC0, Q5HYK1, Q5JWW3, Q5TFK5, Q86VL9, Q86YS5, Q8IYU0, Q9BQJ8, Q9BQM0, Q9BQM1, Q9BQM5, Q9H5U0, Q9HCI2, Q9NXN9	Gene names	C20orf23, KIAA1590, SNX23
Domain Architecture
Description	Kinesin-like motor protein C20orf23 (Sorting nexin-23).

UACA_MOUSE
θ value	3.0926 (rank : 13)	NC score	0.018171 (rank : 25)
Query Neighborhood Hits	39	Target Neighborhood Hits	1620	Shared Neighborhood Hits	21
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

SYMPK_HUMAN
θ value	4.03905 (rank : 14)	NC score	0.049941 (rank : 5)
Query Neighborhood Hits	39	Target Neighborhood Hits	90	Shared Neighborhood Hits	4
SwissProt Accessions	Q92797, O00521, O00689, O00733, Q59GT5, Q8N2U5	Gene names	SYMPK, SPK
Domain Architecture	No domain graphic available
Description	Symplekin.

SYMPK_MOUSE
θ value	4.03905 (rank : 15)	NC score	0.049696 (rank : 6)
Query Neighborhood Hits	39	Target Neighborhood Hits	109	Shared Neighborhood Hits	4
SwissProt Accessions	Q80X82	Gene names	Sympk
Domain Architecture	No domain graphic available
Description	Symplekin.

SYNE2_HUMAN
θ value	4.03905 (rank : 16)	NC score	0.019179 (rank : 21)
Query Neighborhood Hits	39	Target Neighborhood Hits	1323	Shared Neighborhood Hits	19
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

GRAP1_HUMAN
θ value	5.27518 (rank : 17)	NC score	0.021189 (rank : 18)
Query Neighborhood Hits	39	Target Neighborhood Hits	944	Shared Neighborhood Hits	17
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

HEAT2_HUMAN
θ value	5.27518 (rank : 18)	NC score	0.028906 (rank : 7)
Query Neighborhood Hits	39	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q86Y56, Q69YL1, Q96FI9, Q9NX75	Gene names	HEATR2
Domain Architecture	No domain graphic available
Description	HEAT repeat-containing protein 2.

SMRD3_HUMAN
θ value	5.27518 (rank : 19)	NC score	0.020372 (rank : 20)
Query Neighborhood Hits	39	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q6STE5, Q75MJ2, Q75MR8, Q92926, Q9BUH1	Gene names	SMARCD3, BAF60C
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 (60 kDa BRG-1/Brm-associated factor subunit C) (BRG1-associated factor 60C).

SMRD3_MOUSE
θ value	5.27518 (rank : 20)	NC score	0.020375 (rank : 19)
Query Neighborhood Hits	39	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P9Z1, Q921D3, Q9CX89, Q9DB99	Gene names	Smarcd3, Baf60c
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 (60 kDa BRG-1/Brm-associated factor subunit C) (BRG1-associated factor 60C) (mBAF60c).

APOA4_MOUSE
θ value	6.88961 (rank : 21)	NC score	0.024492 (rank : 11)
Query Neighborhood Hits	39	Target Neighborhood Hits	435	Shared Neighborhood Hits	17
SwissProt Accessions	P06728	Gene names	Apoa4
Domain Architecture
Description	Apolipoprotein A-IV precursor (Apo-AIV) (ApoA-IV).

ARL8A_HUMAN
θ value	6.88961 (rank : 22)	NC score	0.005670 (rank : 38)
Query Neighborhood Hits	39	Target Neighborhood Hits	278	Shared Neighborhood Hits	2
SwissProt Accessions	Q96BM9	Gene names	ARL8A, ARL10B, GIE2
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-like protein 8A (ADP-ribosylation factor-like protein 10B) (Novel small G protein indispensable for equal chromosome segregation 2).

CENPE_HUMAN
θ value	6.88961 (rank : 23)	NC score	0.014861 (rank : 31)
Query Neighborhood Hits	39	Target Neighborhood Hits	2060	Shared Neighborhood Hits	19
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

LRRK2_HUMAN
θ value	6.88961 (rank : 24)	NC score	0.002395 (rank : 39)
Query Neighborhood Hits	39	Target Neighborhood Hits	1382	Shared Neighborhood Hits	3
SwissProt Accessions	Q5S007, Q6ZS50, Q8NCX9	Gene names	LRRK2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin).

MYH6_MOUSE
θ value	6.88961 (rank : 25)	NC score	0.015849 (rank : 28)
Query Neighborhood Hits	39	Target Neighborhood Hits	1501	Shared Neighborhood Hits	20
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

NALP1_HUMAN
θ value	6.88961 (rank : 26)	NC score	0.008789 (rank : 33)
Query Neighborhood Hits	39	Target Neighborhood Hits	138	Shared Neighborhood Hits	2
SwissProt Accessions	Q9C000, Q9BZZ8, Q9BZZ9, Q9HAV8, Q9UFT4, Q9Y2E0	Gene names	NALP1, CARD7, DEFCAP, KIAA0926, NAC
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 1 (Death effector filament- forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) (Caspase recruitment domain protein 7).

TRPV5_MOUSE
θ value	6.88961 (rank : 27)	NC score	0.017961 (rank : 26)
Query Neighborhood Hits	39	Target Neighborhood Hits	278	Shared Neighborhood Hits	5
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

UACA_HUMAN
θ value	6.88961 (rank : 28)	NC score	0.017064 (rank : 27)
Query Neighborhood Hits	39	Target Neighborhood Hits	1622	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

CBPE_MOUSE
θ value	8.99809 (rank : 29)	NC score	0.007081 (rank : 37)
Query Neighborhood Hits	39	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q00493, Q64439	Gene names	Cpe
Domain Architecture
Description	Carboxypeptidase E precursor (EC 3.4.17.10) (CPE) (Carboxypeptidase H) (CPH) (Enkephalin convertase) (Prohormone-processing carboxypeptidase).

CCDC6_HUMAN
θ value	8.99809 (rank : 30)	NC score	0.018238 (rank : 24)
Query Neighborhood Hits	39	Target Neighborhood Hits	723	Shared Neighborhood Hits	16
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

ECEL1_MOUSE
θ value	8.99809 (rank : 31)	NC score	0.007689 (rank : 36)
Query Neighborhood Hits	39	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JMI0	Gene names	Ecel1, Dine, Xce
Domain Architecture
Description	Endothelin-converting enzyme-like 1 (EC 3.4.24.-) (Xce protein) (Damage-induced neuronal endopeptidase).

MYH6_HUMAN
θ value	8.99809 (rank : 32)	NC score	0.013451 (rank : 32)
Query Neighborhood Hits	39	Target Neighborhood Hits	1426	Shared Neighborhood Hits	18
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

OLR1_MOUSE
θ value	8.99809 (rank : 33)	NC score	0.015274 (rank : 30)
Query Neighborhood Hits	39	Target Neighborhood Hits	596	Shared Neighborhood Hits	13
SwissProt Accessions	Q9EQ09	Gene names	Olr1, Lox1
Domain Architecture	No domain graphic available
Description	Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) (Lectin-type oxidized LDL receptor 1) (Lectin-like oxidized LDL receptor 1) (Lectin-like oxLDL receptor 1) (LOX-1) [Contains: Oxidized low-density lipoprotein receptor 1, soluble form].

PPME1_HUMAN
θ value	8.99809 (rank : 34)	NC score	0.023456 (rank : 13)
Query Neighborhood Hits	39	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y570, Q9NVT5, Q9UI18	Gene names	PPME1, PME1
Domain Architecture
Description	Protein phosphatase methylesterase 1 (EC 3.1.1.-) (PME-1).

PPME1_MOUSE
θ value	8.99809 (rank : 35)	NC score	0.023200 (rank : 14)
Query Neighborhood Hits	39	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BVQ5, Q3U392, Q3UJX8, Q3UKE0, Q8K311, Q91YR8, Q9CSP7	Gene names	Ppme1, Pme1
Domain Architecture
Description	Protein phosphatase methylesterase 1 (EC 3.1.1.-) (PME-1).

T3JAM_MOUSE
θ value	8.99809 (rank : 36)	NC score	0.018524 (rank : 23)
Query Neighborhood Hits	39	Target Neighborhood Hits	535	Shared Neighborhood Hits	16
SwissProt Accessions	Q8C0G2, Q8BY50, Q8K1Y9	Gene names	Traf3ip3, T3jam
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

WWP1_HUMAN
θ value	8.99809 (rank : 37)	NC score	0.007882 (rank : 35)
Query Neighborhood Hits	39	Target Neighborhood Hits	262	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

WWP1_MOUSE
θ value	8.99809 (rank : 38)	NC score	0.008018 (rank : 34)
Query Neighborhood Hits	39	Target Neighborhood Hits	138	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

ZGPAT_HUMAN
θ value	8.99809 (rank : 39)	NC score	0.022378 (rank : 16)
Query Neighborhood Hits	39	Target Neighborhood Hits	97	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N5A5, Q5JWI9, Q8NC55, Q96JI0, Q96JU4, Q9H401	Gene names	ZGPAT, KIAA1847, ZC3H9, ZC3HDC9
Domain Architecture
Description	Zinc finger CCCH-type with G patch domain protein (Zinc finger CCCH domain-containing protein 9).

Hits sorted by NC score

ORC3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	39	Target Neighborhood Hits	39	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UBD5, Q13565, Q6IUY7, Q9UG44, Q9UNT6	Gene names	ORC3L, LATHEO
Domain Architecture
Description	Origin recognition complex subunit 3 (Origin recognition complex subunit Latheo).

ORC3_MOUSE
NC score	0.981236 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	39	Target Neighborhood Hits	37	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JK30	Gene names	Orc3l, Orc3
Domain Architecture
Description	Origin recognition complex subunit 3 (Origin recognition complex subunit Latheo).

SHLB2_HUMAN
NC score	0.054093 (rank : 3)	θ value	0.365318 (rank : 4)
Query Neighborhood Hits	39	Target Neighborhood Hits	86	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NR46, Q8WY61, Q96JH9	Gene names	SH3GLB2, KIAA1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

SHLB2_MOUSE
NC score	0.053908 (rank : 4)	θ value	0.365318 (rank : 5)
Query Neighborhood Hits	39	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R3V5, Q8K140, Q91ZI7	Gene names	Sh3glb2, Kiaa1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

SYMPK_HUMAN
NC score	0.049941 (rank : 5)	θ value	4.03905 (rank : 14)
Query Neighborhood Hits	39	Target Neighborhood Hits	90	Shared Neighborhood Hits	4
SwissProt Accessions	Q92797, O00521, O00689, O00733, Q59GT5, Q8N2U5	Gene names	SYMPK, SPK
Domain Architecture	No domain graphic available
Description	Symplekin.

SYMPK_MOUSE
NC score	0.049696 (rank : 6)	θ value	4.03905 (rank : 15)
Query Neighborhood Hits	39	Target Neighborhood Hits	109	Shared Neighborhood Hits	4
SwissProt Accessions	Q80X82	Gene names	Sympk
Domain Architecture	No domain graphic available
Description	Symplekin.

HEAT2_HUMAN
NC score	0.028906 (rank : 7)	θ value	5.27518 (rank : 18)
Query Neighborhood Hits	39	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q86Y56, Q69YL1, Q96FI9, Q9NX75	Gene names	HEATR2
Domain Architecture	No domain graphic available
Description	HEAT repeat-containing protein 2.

LRSM1_HUMAN
NC score	0.027427 (rank : 8)	θ value	0.365318 (rank : 3)
Query Neighborhood Hits	39	Target Neighborhood Hits	1078	Shared Neighborhood Hits	20
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

CE290_HUMAN
NC score	0.025980 (rank : 9)	θ value	0.813845 (rank : 6)
Query Neighborhood Hits	39	Target Neighborhood Hits	1553	Shared Neighborhood Hits	19
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

SNX23_HUMAN
NC score	0.024892 (rank : 10)	θ value	3.0926 (rank : 12)
Query Neighborhood Hits	39	Target Neighborhood Hits	944	Shared Neighborhood Hits	18
SwissProt Accessions	Q96L93, Q5HYC0, Q5HYK1, Q5JWW3, Q5TFK5, Q86VL9, Q86YS5, Q8IYU0, Q9BQJ8, Q9BQM0, Q9BQM1, Q9BQM5, Q9H5U0, Q9HCI2, Q9NXN9	Gene names	C20orf23, KIAA1590, SNX23
Domain Architecture
Description	Kinesin-like motor protein C20orf23 (Sorting nexin-23).

APOA4_MOUSE
NC score	0.024492 (rank : 11)	θ value	6.88961 (rank : 21)
Query Neighborhood Hits	39	Target Neighborhood Hits	435	Shared Neighborhood Hits	17
SwissProt Accessions	P06728	Gene names	Apoa4
Domain Architecture
Description	Apolipoprotein A-IV precursor (Apo-AIV) (ApoA-IV).

RBCC1_HUMAN
NC score	0.023997 (rank : 12)	θ value	1.81305 (rank : 9)
Query Neighborhood Hits	39	Target Neighborhood Hits	1023	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

PPME1_HUMAN
NC score	0.023456 (rank : 13)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	39	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y570, Q9NVT5, Q9UI18	Gene names	PPME1, PME1
Domain Architecture
Description	Protein phosphatase methylesterase 1 (EC 3.1.1.-) (PME-1).

PPME1_MOUSE
NC score	0.023200 (rank : 14)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	39	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BVQ5, Q3U392, Q3UJX8, Q3UKE0, Q8K311, Q91YR8, Q9CSP7	Gene names	Ppme1, Pme1
Domain Architecture
Description	Protein phosphatase methylesterase 1 (EC 3.1.1.-) (PME-1).

TRPV5_HUMAN
NC score	0.022944 (rank : 15)	θ value	1.38821 (rank : 7)
Query Neighborhood Hits	39	Target Neighborhood Hits	261	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

ZGPAT_HUMAN
NC score	0.022378 (rank : 16)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	39	Target Neighborhood Hits	97	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N5A5, Q5JWI9, Q8NC55, Q96JI0, Q96JU4, Q9H401	Gene names	ZGPAT, KIAA1847, ZC3H9, ZC3HDC9
Domain Architecture
Description	Zinc finger CCCH-type with G patch domain protein (Zinc finger CCCH domain-containing protein 9).

GRAP1_MOUSE
NC score	0.021324 (rank : 17)	θ value	3.0926 (rank : 11)
Query Neighborhood Hits	39	Target Neighborhood Hits	1234	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

GRAP1_HUMAN
NC score	0.021189 (rank : 18)	θ value	5.27518 (rank : 17)
Query Neighborhood Hits	39	Target Neighborhood Hits	944	Shared Neighborhood Hits	17
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

SMRD3_MOUSE
NC score	0.020375 (rank : 19)	θ value	5.27518 (rank : 20)
Query Neighborhood Hits	39	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P9Z1, Q921D3, Q9CX89, Q9DB99	Gene names	Smarcd3, Baf60c
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 (60 kDa BRG-1/Brm-associated factor subunit C) (BRG1-associated factor 60C) (mBAF60c).

SMRD3_HUMAN
NC score	0.020372 (rank : 20)	θ value	5.27518 (rank : 19)
Query Neighborhood Hits	39	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q6STE5, Q75MJ2, Q75MR8, Q92926, Q9BUH1	Gene names	SMARCD3, BAF60C
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 (60 kDa BRG-1/Brm-associated factor subunit C) (BRG1-associated factor 60C).

SYNE2_HUMAN
NC score	0.019179 (rank : 21)	θ value	4.03905 (rank : 16)
Query Neighborhood Hits	39	Target Neighborhood Hits	1323	Shared Neighborhood Hits	19
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

MYH9_HUMAN
NC score	0.019033 (rank : 22)	θ value	1.81305 (rank : 8)
Query Neighborhood Hits	39	Target Neighborhood Hits	1762	Shared Neighborhood Hits	20
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

T3JAM_MOUSE
NC score	0.018524 (rank : 23)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	39	Target Neighborhood Hits	535	Shared Neighborhood Hits	16
SwissProt Accessions	Q8C0G2, Q8BY50, Q8K1Y9	Gene names	Traf3ip3, T3jam
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

CCDC6_HUMAN
NC score	0.018238 (rank : 24)	θ value	8.99809 (rank : 30)
Query Neighborhood Hits	39	Target Neighborhood Hits	723	Shared Neighborhood Hits	16
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

UACA_MOUSE
NC score	0.018171 (rank : 25)	θ value	3.0926 (rank : 13)
Query Neighborhood Hits	39	Target Neighborhood Hits	1620	Shared Neighborhood Hits	21
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

TRPV5_MOUSE
NC score	0.017961 (rank : 26)	θ value	6.88961 (rank : 27)
Query Neighborhood Hits	39	Target Neighborhood Hits	278	Shared Neighborhood Hits	5
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

UACA_HUMAN
NC score	0.017064 (rank : 27)	θ value	6.88961 (rank : 28)
Query Neighborhood Hits	39	Target Neighborhood Hits	1622	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

MYH6_MOUSE
NC score	0.015849 (rank : 28)	θ value	6.88961 (rank : 25)
Query Neighborhood Hits	39	Target Neighborhood Hits	1501	Shared Neighborhood Hits	20
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

FNBP2_HUMAN
NC score	0.015320 (rank : 29)	θ value	3.0926 (rank : 10)
Query Neighborhood Hits	39	Target Neighborhood Hits	432	Shared Neighborhood Hits	12
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

OLR1_MOUSE
NC score	0.015274 (rank : 30)	θ value	8.99809 (rank : 33)
Query Neighborhood Hits	39	Target Neighborhood Hits	596	Shared Neighborhood Hits	13
SwissProt Accessions	Q9EQ09	Gene names	Olr1, Lox1
Domain Architecture	No domain graphic available
Description	Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) (Lectin-type oxidized LDL receptor 1) (Lectin-like oxidized LDL receptor 1) (Lectin-like oxLDL receptor 1) (LOX-1) [Contains: Oxidized low-density lipoprotein receptor 1, soluble form].

CENPE_HUMAN
NC score	0.014861 (rank : 31)	θ value	6.88961 (rank : 23)
Query Neighborhood Hits	39	Target Neighborhood Hits	2060	Shared Neighborhood Hits	19
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

MYH6_HUMAN
NC score	0.013451 (rank : 32)	θ value	8.99809 (rank : 32)
Query Neighborhood Hits	39	Target Neighborhood Hits	1426	Shared Neighborhood Hits	18
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

NALP1_HUMAN
NC score	0.008789 (rank : 33)	θ value	6.88961 (rank : 26)
Query Neighborhood Hits	39	Target Neighborhood Hits	138	Shared Neighborhood Hits	2
SwissProt Accessions	Q9C000, Q9BZZ8, Q9BZZ9, Q9HAV8, Q9UFT4, Q9Y2E0	Gene names	NALP1, CARD7, DEFCAP, KIAA0926, NAC
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 1 (Death effector filament- forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) (Caspase recruitment domain protein 7).

WWP1_MOUSE
NC score	0.008018 (rank : 34)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	39	Target Neighborhood Hits	138	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

WWP1_HUMAN
NC score	0.007882 (rank : 35)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	39	Target Neighborhood Hits	262	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

ECEL1_MOUSE
NC score	0.007689 (rank : 36)	θ value	8.99809 (rank : 31)
Query Neighborhood Hits	39	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JMI0	Gene names	Ecel1, Dine, Xce
Domain Architecture
Description	Endothelin-converting enzyme-like 1 (EC 3.4.24.-) (Xce protein) (Damage-induced neuronal endopeptidase).

CBPE_MOUSE
NC score	0.007081 (rank : 37)	θ value	8.99809 (rank : 29)
Query Neighborhood Hits	39	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q00493, Q64439	Gene names	Cpe
Domain Architecture
Description	Carboxypeptidase E precursor (EC 3.4.17.10) (CPE) (Carboxypeptidase H) (CPH) (Enkephalin convertase) (Prohormone-processing carboxypeptidase).

ARL8A_HUMAN
NC score	0.005670 (rank : 38)	θ value	6.88961 (rank : 22)
Query Neighborhood Hits	39	Target Neighborhood Hits	278	Shared Neighborhood Hits	2
SwissProt Accessions	Q96BM9	Gene names	ARL8A, ARL10B, GIE2
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-like protein 8A (ADP-ribosylation factor-like protein 10B) (Novel small G protein indispensable for equal chromosome segregation 2).

LRRK2_HUMAN
NC score	0.002395 (rank : 39)	θ value	6.88961 (rank : 24)
Query Neighborhood Hits	39	Target Neighborhood Hits	1382	Shared Neighborhood Hits	3
SwissProt Accessions	Q5S007, Q6ZS50, Q8NCX9	Gene names	LRRK2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin).