Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : APBB1_MOUSE

For an explanation of this page, click here

APBB1_MOUSE
SwissProt Accessions	Q9QXJ1, O08642, Q3TPU0, Q8BNF4, Q8BSR9	Gene names	Apbb1, Fe65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

APBB1_HUMAN
θ value	0 (rank : 1)	NC score	0.994880 (rank : 2)
Query Neighborhood Hits	75	Target Neighborhood Hits	62	Shared Neighborhood Hits	48
SwissProt Accessions	O00213, Q96A93	Gene names	APBB1, FE65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

APBB1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	75	Target Neighborhood Hits	75	Shared Neighborhood Hits	75
SwissProt Accessions	Q9QXJ1, O08642, Q3TPU0, Q8BNF4, Q8BSR9	Gene names	Apbb1, Fe65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

APBB2_MOUSE
θ value	1.19589e-169 (rank : 3)	NC score	0.954673 (rank : 3)
Query Neighborhood Hits	75	Target Neighborhood Hits	88	Shared Neighborhood Hits	26
SwissProt Accessions	Q9DBR4, Q6DFX8	Gene names	Apbb2
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2.

APBB2_HUMAN
θ value	4.25343e-167 (rank : 4)	NC score	0.950655 (rank : 4)
Query Neighborhood Hits	75	Target Neighborhood Hits	96	Shared Neighborhood Hits	28
SwissProt Accessions	Q92870, Q8IUI6	Gene names	APBB2, FE65L, FE65L1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2 (Fe65-like protein).

APBB3_HUMAN
θ value	3.1125e-93 (rank : 5)	NC score	0.938039 (rank : 6)
Query Neighborhood Hits	75	Target Neighborhood Hits	36	Shared Neighborhood Hits	18
SwissProt Accessions	O95704, Q9NYX6, Q9NYX7, Q9NYX8	Gene names	APBB3, FE65L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 3 (Fe65-like protein 2) (Fe65L2).

APBB3_MOUSE
θ value	8.47616e-91 (rank : 6)	NC score	0.938152 (rank : 5)
Query Neighborhood Hits	75	Target Neighborhood Hits	32	Shared Neighborhood Hits	18
SwissProt Accessions	Q8R1C9	Gene names	Apbb3
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 3.

BCAS1_HUMAN
θ value	0.00665767 (rank : 7)	NC score	0.089634 (rank : 15)
Query Neighborhood Hits	75	Target Neighborhood Hits	133	Shared Neighborhood Hits	4
SwissProt Accessions	O75363, Q68CZ3	Gene names	BCAS1, AIBC1, NABC1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 1 (Novel amplified in breast cancer 1) (Amplified and overexpressed in breast cancer).

SETD2_HUMAN
θ value	0.0148317 (rank : 8)	NC score	0.129527 (rank : 7)
Query Neighborhood Hits	75	Target Neighborhood Hits	412	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

PSN2_HUMAN
θ value	0.0330416 (rank : 9)	NC score	0.080734 (rank : 24)
Query Neighborhood Hits	75	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	P49810, Q96P32	Gene names	PSEN2, AD4, PS2, PSNL2, STM2
Domain Architecture
Description	Presenilin-2 (EC 3.4.23.-) (PS-2) (STM-2) (E5-1) (AD3LP) (AD5) [Contains: Presenilin-2 NTF subunit; Presenilin-2 CTF subunit].

YAP1_HUMAN
θ value	0.0330416 (rank : 10)	NC score	0.098023 (rank : 13)
Query Neighborhood Hits	75	Target Neighborhood Hits	173	Shared Neighborhood Hits	19
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

WWP2_HUMAN
θ value	0.0961366 (rank : 11)	NC score	0.098110 (rank : 12)
Query Neighborhood Hits	75	Target Neighborhood Hits	177	Shared Neighborhood Hits	25
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

WWP2_MOUSE
θ value	0.0961366 (rank : 12)	NC score	0.110383 (rank : 10)
Query Neighborhood Hits	75	Target Neighborhood Hits	118	Shared Neighborhood Hits	23
SwissProt Accessions	Q9DBH0, Q8BTG4, Q923F6	Gene names	Wwp2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2).

PSN2_MOUSE
θ value	0.163984 (rank : 13)	NC score	0.071493 (rank : 31)
Query Neighborhood Hits	75	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q61144, O54977, P97934, P97935, Q91VS3, Q9D616	Gene names	Psen2, Ad4h, Alg3, Ps-2, Psnl2
Domain Architecture
Description	Presenilin-2 (EC 3.4.23.-) (PS-2) [Contains: Presenilin-2 NTF subunit; Presenilin-2 CTF subunit].

SMUF2_HUMAN
θ value	0.163984 (rank : 14)	NC score	0.085114 (rank : 19)
Query Neighborhood Hits	75	Target Neighborhood Hits	142	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

SMRC2_HUMAN
θ value	0.21417 (rank : 15)	NC score	0.046023 (rank : 42)
Query Neighborhood Hits	75	Target Neighborhood Hits	499	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

YAP1_MOUSE
θ value	0.365318 (rank : 16)	NC score	0.085122 (rank : 18)
Query Neighborhood Hits	75	Target Neighborhood Hits	96	Shared Neighborhood Hits	19
SwissProt Accessions	P46938, Q52KJ5	Gene names	Yap1, Yap, Yap65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

AL2SA_HUMAN
θ value	0.47712 (rank : 17)	NC score	0.065398 (rank : 34)
Query Neighborhood Hits	75	Target Neighborhood Hits	97	Shared Neighborhood Hits	5
SwissProt Accessions	Q53TS8, Q8NCN6, Q96LN4	Gene names	ALS2CR11
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 11 protein.

SMRC2_MOUSE
θ value	0.47712 (rank : 18)	NC score	0.042429 (rank : 43)
Query Neighborhood Hits	75	Target Neighborhood Hits	487	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

PCNT_MOUSE
θ value	0.62314 (rank : 19)	NC score	0.012646 (rank : 55)
Query Neighborhood Hits	75	Target Neighborhood Hits	1207	Shared Neighborhood Hits	11
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

ANK2_HUMAN
θ value	0.813845 (rank : 20)	NC score	0.011475 (rank : 59)
Query Neighborhood Hits	75	Target Neighborhood Hits	1615	Shared Neighborhood Hits	24
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

MY18A_MOUSE
θ value	0.813845 (rank : 21)	NC score	0.007035 (rank : 73)
Query Neighborhood Hits	75	Target Neighborhood Hits	1989	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

NUMB_HUMAN
θ value	0.813845 (rank : 22)	NC score	0.071348 (rank : 32)
Query Neighborhood Hits	75	Target Neighborhood Hits	112	Shared Neighborhood Hits	15
SwissProt Accessions	P49757, Q6NUQ7, Q86SY1, Q8WW73, Q9UBG1, Q9UEQ4, Q9UKE8, Q9UKE9, Q9UKF0, Q9UQJ4	Gene names	NUMB
Domain Architecture
Description	Protein numb homolog (h-Numb) (Protein S171).

NUMB_MOUSE
θ value	0.813845 (rank : 23)	NC score	0.071167 (rank : 33)
Query Neighborhood Hits	75	Target Neighborhood Hits	91	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QZS3, P70422, Q8CIB1, Q9DC57, Q9QZR1, Q9QZS4	Gene names	Numb
Domain Architecture
Description	Protein numb homolog (m-Numb) (m-Nb).

ATS12_HUMAN
θ value	1.06291 (rank : 24)	NC score	0.010450 (rank : 63)
Query Neighborhood Hits	75	Target Neighborhood Hits	251	Shared Neighborhood Hits	6
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

HUWE1_MOUSE
θ value	1.06291 (rank : 25)	NC score	0.051725 (rank : 41)
Query Neighborhood Hits	75	Target Neighborhood Hits	406	Shared Neighborhood Hits	18
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

IMMT_MOUSE
θ value	1.06291 (rank : 26)	NC score	0.029827 (rank : 45)
Query Neighborhood Hits	75	Target Neighborhood Hits	326	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CAQ8, Q66JS4, Q7TNE2, Q8C7V1, Q8CCI0, Q8CDA8, Q9D9F6	Gene names	Immt
Domain Architecture	No domain graphic available
Description	Mitochondrial inner membrane protein (Mitofilin).

WWP1_MOUSE
θ value	1.06291 (rank : 27)	NC score	0.089608 (rank : 16)
Query Neighborhood Hits	75	Target Neighborhood Hits	138	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

CAPON_HUMAN
θ value	1.38821 (rank : 28)	NC score	0.089246 (rank : 17)
Query Neighborhood Hits	75	Target Neighborhood Hits	35	Shared Neighborhood Hits	12
SwissProt Accessions	O75052, O43564	Gene names	NOS1AP, CAPON, KIAA0464
Domain Architecture	No domain graphic available
Description	Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C--terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein).

JIP1_HUMAN
θ value	1.38821 (rank : 29)	NC score	0.081784 (rank : 23)
Query Neighborhood Hits	75	Target Neighborhood Hits	271	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

PIN1_MOUSE
θ value	1.38821 (rank : 30)	NC score	0.126081 (rank : 8)
Query Neighborhood Hits	75	Target Neighborhood Hits	60	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QUR7, Q543B3	Gene names	Pin1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

WWP1_HUMAN
θ value	1.38821 (rank : 31)	NC score	0.095973 (rank : 14)
Query Neighborhood Hits	75	Target Neighborhood Hits	262	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

KCT2_HUMAN
θ value	1.81305 (rank : 32)	NC score	0.029740 (rank : 46)
Query Neighborhood Hits	75	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NC54, Q9NRG2	Gene names	KCT2, C5orf15
Domain Architecture	No domain graphic available
Description	Keratinocytes-associated transmembrane protein 2 precursor.

NED4L_MOUSE
θ value	1.81305 (rank : 33)	NC score	0.078930 (rank : 28)
Query Neighborhood Hits	75	Target Neighborhood Hits	231	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

PGCB_HUMAN
θ value	1.81305 (rank : 34)	NC score	0.009180 (rank : 67)
Query Neighborhood Hits	75	Target Neighborhood Hits	478	Shared Neighborhood Hits	7
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

TARA_HUMAN
θ value	1.81305 (rank : 35)	NC score	0.015564 (rank : 51)
Query Neighborhood Hits	75	Target Neighborhood Hits	1626	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

CAPON_MOUSE
θ value	2.36792 (rank : 36)	NC score	0.080669 (rank : 25)
Query Neighborhood Hits	75	Target Neighborhood Hits	34	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D3A8, Q80TZ6	Gene names	Nos1ap, Capon, Kiaa0464
Domain Architecture	No domain graphic available
Description	Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C--terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein).

CMGA_HUMAN
θ value	2.36792 (rank : 37)	NC score	0.040177 (rank : 44)
Query Neighborhood Hits	75	Target Neighborhood Hits	238	Shared Neighborhood Hits	8
SwissProt Accessions	P10645, Q96E84, Q96GL7, Q9BQB5	Gene names	CHGA
Domain Architecture
Description	Chromogranin A precursor (CgA) (Pituitary secretory protein I) (SP-I) [Contains: Vasostatin-1 (Vasostatin I); Vasostatin-2 (Vasostatin II); EA-92; ES-43; Pancreastatin; SS-18; WA-8; WE-14; LF-19; AL-11; GV-19; GR-44; ER-37].

DHX57_MOUSE
θ value	2.36792 (rank : 38)	NC score	0.009428 (rank : 65)
Query Neighborhood Hits	75	Target Neighborhood Hits	125	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P5D3, Q3TS93, Q6NZK4, Q6P1B4, Q8BI63, Q8BIA2, Q8R360	Gene names	Dhx57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

LAP4_MOUSE
θ value	2.36792 (rank : 39)	NC score	0.004936 (rank : 76)
Query Neighborhood Hits	75	Target Neighborhood Hits	590	Shared Neighborhood Hits	6
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

NED4L_HUMAN
θ value	2.36792 (rank : 40)	NC score	0.080126 (rank : 26)
Query Neighborhood Hits	75	Target Neighborhood Hits	238	Shared Neighborhood Hits	26
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

OBSCN_HUMAN
θ value	2.36792 (rank : 41)	NC score	0.000920 (rank : 82)
Query Neighborhood Hits	75	Target Neighborhood Hits	1931	Shared Neighborhood Hits	12
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

SPRL1_MOUSE
θ value	2.36792 (rank : 42)	NC score	0.016707 (rank : 50)
Query Neighborhood Hits	75	Target Neighborhood Hits	403	Shared Neighborhood Hits	11
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

ARH_MOUSE
θ value	3.0926 (rank : 43)	NC score	0.083463 (rank : 20)
Query Neighborhood Hits	75	Target Neighborhood Hits	32	Shared Neighborhood Hits	12
SwissProt Accessions	Q8C142, Q6NWV6, Q8VDQ0	Gene names	Ldlrap1, Arh
Domain Architecture	No domain graphic available
Description	Low density lipoprotein receptor adapter protein 1 (Autosomal recessive hypercholesterolemia protein homolog).

NEDD4_HUMAN
θ value	3.0926 (rank : 44)	NC score	0.083345 (rank : 21)
Query Neighborhood Hits	75	Target Neighborhood Hits	214	Shared Neighborhood Hits	23
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

ANR41_HUMAN
θ value	4.03905 (rank : 45)	NC score	0.012052 (rank : 56)
Query Neighborhood Hits	75	Target Neighborhood Hits	332	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

ARHGC_HUMAN
θ value	4.03905 (rank : 46)	NC score	0.009192 (rank : 66)
Query Neighborhood Hits	75	Target Neighborhood Hits	351	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARH_HUMAN
θ value	4.03905 (rank : 47)	NC score	0.083029 (rank : 22)
Query Neighborhood Hits	75	Target Neighborhood Hits	38	Shared Neighborhood Hits	12
SwissProt Accessions	Q5SW96, Q6TQS9, Q8N2Y0, Q9UFI9	Gene names	LDLRAP1, ARH
Domain Architecture	No domain graphic available
Description	Low density lipoprotein receptor adapter protein 1 (Autosomal recessive hypercholesterolemia protein).

JIP1_MOUSE
θ value	4.03905 (rank : 48)	NC score	0.065342 (rank : 35)
Query Neighborhood Hits	75	Target Neighborhood Hits	259	Shared Neighborhood Hits	14
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

KR104_HUMAN
θ value	4.03905 (rank : 49)	NC score	0.015273 (rank : 53)
Query Neighborhood Hits	75	Target Neighborhood Hits	313	Shared Neighborhood Hits	5
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

OLIG1_HUMAN
θ value	4.03905 (rank : 50)	NC score	0.013028 (rank : 54)
Query Neighborhood Hits	75	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TAK6, Q7RTS0	Gene names	OLIG1
Domain Architecture
Description	Oligodendrocyte transcription factor 1 (Oligo1).

OSBL8_HUMAN
θ value	4.03905 (rank : 51)	NC score	0.010594 (rank : 62)
Query Neighborhood Hits	75	Target Neighborhood Hits	289	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

PGFRA_HUMAN
θ value	4.03905 (rank : 52)	NC score	0.002023 (rank : 80)
Query Neighborhood Hits	75	Target Neighborhood Hits	980	Shared Neighborhood Hits	4
SwissProt Accessions	P16234, Q96KZ7	Gene names	PDGFRA
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

PVRL2_MOUSE
θ value	4.03905 (rank : 53)	NC score	0.022173 (rank : 47)
Query Neighborhood Hits	75	Target Neighborhood Hits	242	Shared Neighborhood Hits	6
SwissProt Accessions	P32507, Q62096	Gene names	Pvrl2, Mph, Pvr, Pvs
Domain Architecture
Description	Poliovirus receptor-related protein 2 precursor (Murine herpesvirus entry protein B) (mHveB) (Nectin-2) (Poliovirus receptor homolog) (CD112 antigen).

RGS3_MOUSE
θ value	4.03905 (rank : 54)	NC score	0.011512 (rank : 58)
Query Neighborhood Hits	75	Target Neighborhood Hits	1621	Shared Neighborhood Hits	25
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SPAG1_MOUSE
θ value	4.03905 (rank : 55)	NC score	0.015527 (rank : 52)
Query Neighborhood Hits	75	Target Neighborhood Hits	218	Shared Neighborhood Hits	3
SwissProt Accessions	Q80ZX8, Q8CCK7, Q9QZJ3, Q9QZJ4	Gene names	Spag1, Tpis
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 1 (Infertility-related sperm protein Spag-1) (TPR-containing protein involved in spermatogenesis) (TPIS).

TACC2_MOUSE
θ value	4.03905 (rank : 56)	NC score	0.011024 (rank : 60)
Query Neighborhood Hits	75	Target Neighborhood Hits	774	Shared Neighborhood Hits	12
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

WWTR1_HUMAN
θ value	4.03905 (rank : 57)	NC score	0.061168 (rank : 37)
Query Neighborhood Hits	75	Target Neighborhood Hits	76	Shared Neighborhood Hits	16
SwissProt Accessions	Q9GZV5, Q8N3P2, Q9Y3W6	Gene names	WWTR1, TAZ
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

CO5A2_HUMAN
θ value	5.27518 (rank : 58)	NC score	0.005658 (rank : 74)
Query Neighborhood Hits	75	Target Neighborhood Hits	760	Shared Neighborhood Hits	10
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

IMMT_HUMAN
θ value	5.27518 (rank : 59)	NC score	0.020967 (rank : 48)
Query Neighborhood Hits	75	Target Neighborhood Hits	494	Shared Neighborhood Hits	10
SwissProt Accessions	Q16891, Q14539, Q15092, Q68D41, Q69HW5, Q6IBL0, Q7Z3X1, Q8TAJ5, Q9P0V2	Gene names	IMMT, HMP, PIG4
Domain Architecture	No domain graphic available
Description	Mitochondrial inner membrane protein (Mitofilin) (p87/89) (Proliferation-inducing gene 4 protein).

NEDD4_MOUSE
θ value	5.27518 (rank : 60)	NC score	0.079794 (rank : 27)
Query Neighborhood Hits	75	Target Neighborhood Hits	212	Shared Neighborhood Hits	23
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

PGFRA_MOUSE
θ value	5.27518 (rank : 61)	NC score	0.001821 (rank : 81)
Query Neighborhood Hits	75	Target Neighborhood Hits	975	Shared Neighborhood Hits	4
SwissProt Accessions	P26618, Q62046	Gene names	Pdgfra
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

UBP8_HUMAN
θ value	5.27518 (rank : 62)	NC score	0.011677 (rank : 57)
Query Neighborhood Hits	75	Target Neighborhood Hits	751	Shared Neighborhood Hits	15
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

WDR24_MOUSE
θ value	5.27518 (rank : 63)	NC score	0.007088 (rank : 72)
Query Neighborhood Hits	75	Target Neighborhood Hits	286	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CFJ9	Gene names	Wdr24
Domain Architecture	No domain graphic available
Description	WD repeat protein 24.

ANK1_HUMAN
θ value	6.88961 (rank : 64)	NC score	0.008444 (rank : 70)
Query Neighborhood Hits	75	Target Neighborhood Hits	416	Shared Neighborhood Hits	5
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

K0528_MOUSE
θ value	6.88961 (rank : 65)	NC score	0.010899 (rank : 61)
Query Neighborhood Hits	75	Target Neighborhood Hits	102	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TPS5, Q3TQY6, Q6A052, Q80VA1, Q8C0U3, Q8CID5, Q9CS85	Gene names	Kiaa0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

LEO1_MOUSE
θ value	6.88961 (rank : 66)	NC score	0.008697 (rank : 69)
Query Neighborhood Hits	75	Target Neighborhood Hits	946	Shared Neighborhood Hits	12
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

PVRL2_HUMAN
θ value	6.88961 (rank : 67)	NC score	0.020290 (rank : 49)
Query Neighborhood Hits	75	Target Neighborhood Hits	185	Shared Neighborhood Hits	5
SwissProt Accessions	Q92692, O75455, Q96J29	Gene names	PVRL2, HVEB, PRR2
Domain Architecture
Description	Poliovirus receptor-related protein 2 precursor (Herpes virus entry mediator B) (HveB) (Nectin-2) (CD112 antigen).

ABC8B_MOUSE
θ value	8.99809 (rank : 68)	NC score	0.002681 (rank : 79)
Query Neighborhood Hits	75	Target Neighborhood Hits	124	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K440, Q69ZY4, Q8BRQ1, Q9JL38	Gene names	Abca8b, Abca8, Kiaa0822
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 8-B.

BRD8_HUMAN
θ value	8.99809 (rank : 69)	NC score	0.008151 (rank : 71)
Query Neighborhood Hits	75	Target Neighborhood Hits	292	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

GRB10_HUMAN
θ value	8.99809 (rank : 70)	NC score	0.004927 (rank : 77)
Query Neighborhood Hits	75	Target Neighborhood Hits	147	Shared Neighborhood Hits	2
SwissProt Accessions	Q13322, O00427, O00701, O75222, Q92606, Q92907, Q92948	Gene names	GRB10, GRBIR, KIAA0207
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein) (Insulin receptor-binding protein GRB-IR).

KR10B_HUMAN
θ value	8.99809 (rank : 71)	NC score	0.005335 (rank : 75)
Query Neighborhood Hits	75	Target Neighborhood Hits	269	Shared Neighborhood Hits	3
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

MY18A_HUMAN
θ value	8.99809 (rank : 72)	NC score	0.004724 (rank : 78)
Query Neighborhood Hits	75	Target Neighborhood Hits	1929	Shared Neighborhood Hits	18
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

PINL_HUMAN
θ value	8.99809 (rank : 73)	NC score	0.114875 (rank : 9)
Query Neighborhood Hits	75	Target Neighborhood Hits	47	Shared Neighborhood Hits	21
SwissProt Accessions	O15428	Gene names	PIN1L
Domain Architecture
Description	PIN1-like protein.

TAU_MOUSE
θ value	8.99809 (rank : 74)	NC score	0.008970 (rank : 68)
Query Neighborhood Hits	75	Target Neighborhood Hits	502	Shared Neighborhood Hits	9
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

UBP8_MOUSE
θ value	8.99809 (rank : 75)	NC score	0.009989 (rank : 64)
Query Neighborhood Hits	75	Target Neighborhood Hits	362	Shared Neighborhood Hits	14
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

GAS7_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.064246 (rank : 36)
Query Neighborhood Hits	75	Target Neighborhood Hits	258	Shared Neighborhood Hits	20
SwissProt Accessions	O60861, O43144	Gene names	GAS7, KIAA0394
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

GAS7_MOUSE
θ value	θ > 10 (rank : 77)	NC score	0.052242 (rank : 40)
Query Neighborhood Hits	75	Target Neighborhood Hits	259	Shared Neighborhood Hits	21
SwissProt Accessions	Q60780, Q9QY25, Q9QY26, Q9QY34	Gene names	Gas7
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

ITCH_HUMAN
θ value	θ > 10 (rank : 78)	NC score	0.072168 (rank : 30)
Query Neighborhood Hits	75	Target Neighborhood Hits	162	Shared Neighborhood Hits	20
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

ITCH_MOUSE
θ value	θ > 10 (rank : 79)	NC score	0.075399 (rank : 29)
Query Neighborhood Hits	75	Target Neighborhood Hits	127	Shared Neighborhood Hits	21
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

NUMBL_MOUSE
θ value	θ > 10 (rank : 80)	NC score	0.052608 (rank : 39)
Query Neighborhood Hits	75	Target Neighborhood Hits	147	Shared Neighborhood Hits	11
SwissProt Accessions	O08919, Q6NVG8	Gene names	Numbl, Nbl
Domain Architecture
Description	Numb-like protein.

PIN1_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.100209 (rank : 11)
Query Neighborhood Hits	75	Target Neighborhood Hits	59	Shared Neighborhood Hits	19
SwissProt Accessions	Q13526	Gene names	PIN1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

SMUF1_MOUSE
θ value	θ > 10 (rank : 82)	NC score	0.055872 (rank : 38)
Query Neighborhood Hits	75	Target Neighborhood Hits	142	Shared Neighborhood Hits	18
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

Hits sorted by NC score

APBB1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	75	Target Neighborhood Hits	75	Shared Neighborhood Hits	75
SwissProt Accessions	Q9QXJ1, O08642, Q3TPU0, Q8BNF4, Q8BSR9	Gene names	Apbb1, Fe65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

APBB1_HUMAN
NC score	0.994880 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	75	Target Neighborhood Hits	62	Shared Neighborhood Hits	48
SwissProt Accessions	O00213, Q96A93	Gene names	APBB1, FE65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

APBB2_MOUSE
NC score	0.954673 (rank : 3)	θ value	1.19589e-169 (rank : 3)
Query Neighborhood Hits	75	Target Neighborhood Hits	88	Shared Neighborhood Hits	26
SwissProt Accessions	Q9DBR4, Q6DFX8	Gene names	Apbb2
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2.

APBB2_HUMAN
NC score	0.950655 (rank : 4)	θ value	4.25343e-167 (rank : 4)
Query Neighborhood Hits	75	Target Neighborhood Hits	96	Shared Neighborhood Hits	28
SwissProt Accessions	Q92870, Q8IUI6	Gene names	APBB2, FE65L, FE65L1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2 (Fe65-like protein).

APBB3_MOUSE
NC score	0.938152 (rank : 5)	θ value	8.47616e-91 (rank : 6)
Query Neighborhood Hits	75	Target Neighborhood Hits	32	Shared Neighborhood Hits	18
SwissProt Accessions	Q8R1C9	Gene names	Apbb3
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 3.

APBB3_HUMAN
NC score	0.938039 (rank : 6)	θ value	3.1125e-93 (rank : 5)
Query Neighborhood Hits	75	Target Neighborhood Hits	36	Shared Neighborhood Hits	18
SwissProt Accessions	O95704, Q9NYX6, Q9NYX7, Q9NYX8	Gene names	APBB3, FE65L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 3 (Fe65-like protein 2) (Fe65L2).

SETD2_HUMAN
NC score	0.129527 (rank : 7)	θ value	0.0148317 (rank : 8)
Query Neighborhood Hits	75	Target Neighborhood Hits	412	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

PIN1_MOUSE
NC score	0.126081 (rank : 8)	θ value	1.38821 (rank : 30)
Query Neighborhood Hits	75	Target Neighborhood Hits	60	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QUR7, Q543B3	Gene names	Pin1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

PINL_HUMAN
NC score	0.114875 (rank : 9)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	75	Target Neighborhood Hits	47	Shared Neighborhood Hits	21
SwissProt Accessions	O15428	Gene names	PIN1L
Domain Architecture
Description	PIN1-like protein.

WWP2_MOUSE
NC score	0.110383 (rank : 10)	θ value	0.0961366 (rank : 12)
Query Neighborhood Hits	75	Target Neighborhood Hits	118	Shared Neighborhood Hits	23
SwissProt Accessions	Q9DBH0, Q8BTG4, Q923F6	Gene names	Wwp2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2).

PIN1_HUMAN
NC score	0.100209 (rank : 11)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	75	Target Neighborhood Hits	59	Shared Neighborhood Hits	19
SwissProt Accessions	Q13526	Gene names	PIN1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

WWP2_HUMAN
NC score	0.098110 (rank : 12)	θ value	0.0961366 (rank : 11)
Query Neighborhood Hits	75	Target Neighborhood Hits	177	Shared Neighborhood Hits	25
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

YAP1_HUMAN
NC score	0.098023 (rank : 13)	θ value	0.0330416 (rank : 10)
Query Neighborhood Hits	75	Target Neighborhood Hits	173	Shared Neighborhood Hits	19
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

WWP1_HUMAN
NC score	0.095973 (rank : 14)	θ value	1.38821 (rank : 31)
Query Neighborhood Hits	75	Target Neighborhood Hits	262	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

BCAS1_HUMAN
NC score	0.089634 (rank : 15)	θ value	0.00665767 (rank : 7)
Query Neighborhood Hits	75	Target Neighborhood Hits	133	Shared Neighborhood Hits	4
SwissProt Accessions	O75363, Q68CZ3	Gene names	BCAS1, AIBC1, NABC1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 1 (Novel amplified in breast cancer 1) (Amplified and overexpressed in breast cancer).

WWP1_MOUSE
NC score	0.089608 (rank : 16)	θ value	1.06291 (rank : 27)
Query Neighborhood Hits	75	Target Neighborhood Hits	138	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

CAPON_HUMAN
NC score	0.089246 (rank : 17)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	75	Target Neighborhood Hits	35	Shared Neighborhood Hits	12
SwissProt Accessions	O75052, O43564	Gene names	NOS1AP, CAPON, KIAA0464
Domain Architecture	No domain graphic available
Description	Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C--terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein).

YAP1_MOUSE
NC score	0.085122 (rank : 18)	θ value	0.365318 (rank : 16)
Query Neighborhood Hits	75	Target Neighborhood Hits	96	Shared Neighborhood Hits	19
SwissProt Accessions	P46938, Q52KJ5	Gene names	Yap1, Yap, Yap65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

SMUF2_HUMAN
NC score	0.085114 (rank : 19)	θ value	0.163984 (rank : 14)
Query Neighborhood Hits	75	Target Neighborhood Hits	142	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

ARH_MOUSE
NC score	0.083463 (rank : 20)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	75	Target Neighborhood Hits	32	Shared Neighborhood Hits	12
SwissProt Accessions	Q8C142, Q6NWV6, Q8VDQ0	Gene names	Ldlrap1, Arh
Domain Architecture	No domain graphic available
Description	Low density lipoprotein receptor adapter protein 1 (Autosomal recessive hypercholesterolemia protein homolog).

NEDD4_HUMAN
NC score	0.083345 (rank : 21)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	75	Target Neighborhood Hits	214	Shared Neighborhood Hits	23
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

ARH_HUMAN
NC score	0.083029 (rank : 22)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	75	Target Neighborhood Hits	38	Shared Neighborhood Hits	12
SwissProt Accessions	Q5SW96, Q6TQS9, Q8N2Y0, Q9UFI9	Gene names	LDLRAP1, ARH
Domain Architecture	No domain graphic available
Description	Low density lipoprotein receptor adapter protein 1 (Autosomal recessive hypercholesterolemia protein).

JIP1_HUMAN
NC score	0.081784 (rank : 23)	θ value	1.38821 (rank : 29)
Query Neighborhood Hits	75	Target Neighborhood Hits	271	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

PSN2_HUMAN
NC score	0.080734 (rank : 24)	θ value	0.0330416 (rank : 9)
Query Neighborhood Hits	75	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	P49810, Q96P32	Gene names	PSEN2, AD4, PS2, PSNL2, STM2
Domain Architecture
Description	Presenilin-2 (EC 3.4.23.-) (PS-2) (STM-2) (E5-1) (AD3LP) (AD5) [Contains: Presenilin-2 NTF subunit; Presenilin-2 CTF subunit].

CAPON_MOUSE
NC score	0.080669 (rank : 25)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	75	Target Neighborhood Hits	34	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D3A8, Q80TZ6	Gene names	Nos1ap, Capon, Kiaa0464
Domain Architecture	No domain graphic available
Description	Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C--terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein).

NED4L_HUMAN
NC score	0.080126 (rank : 26)	θ value	2.36792 (rank : 40)
Query Neighborhood Hits	75	Target Neighborhood Hits	238	Shared Neighborhood Hits	26
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NEDD4_MOUSE
NC score	0.079794 (rank : 27)	θ value	5.27518 (rank : 60)
Query Neighborhood Hits	75	Target Neighborhood Hits	212	Shared Neighborhood Hits	23
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

NED4L_MOUSE
NC score	0.078930 (rank : 28)	θ value	1.81305 (rank : 33)
Query Neighborhood Hits	75	Target Neighborhood Hits	231	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

ITCH_MOUSE
NC score	0.075399 (rank : 29)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	75	Target Neighborhood Hits	127	Shared Neighborhood Hits	21
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

ITCH_HUMAN
NC score	0.072168 (rank : 30)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	75	Target Neighborhood Hits	162	Shared Neighborhood Hits	20
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

PSN2_MOUSE
NC score	0.071493 (rank : 31)	θ value	0.163984 (rank : 13)
Query Neighborhood Hits	75	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q61144, O54977, P97934, P97935, Q91VS3, Q9D616	Gene names	Psen2, Ad4h, Alg3, Ps-2, Psnl2
Domain Architecture
Description	Presenilin-2 (EC 3.4.23.-) (PS-2) [Contains: Presenilin-2 NTF subunit; Presenilin-2 CTF subunit].

NUMB_HUMAN
NC score	0.071348 (rank : 32)	θ value	0.813845 (rank : 22)
Query Neighborhood Hits	75	Target Neighborhood Hits	112	Shared Neighborhood Hits	15
SwissProt Accessions	P49757, Q6NUQ7, Q86SY1, Q8WW73, Q9UBG1, Q9UEQ4, Q9UKE8, Q9UKE9, Q9UKF0, Q9UQJ4	Gene names	NUMB
Domain Architecture
Description	Protein numb homolog (h-Numb) (Protein S171).

NUMB_MOUSE
NC score	0.071167 (rank : 33)	θ value	0.813845 (rank : 23)
Query Neighborhood Hits	75	Target Neighborhood Hits	91	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QZS3, P70422, Q8CIB1, Q9DC57, Q9QZR1, Q9QZS4	Gene names	Numb
Domain Architecture
Description	Protein numb homolog (m-Numb) (m-Nb).

AL2SA_HUMAN
NC score	0.065398 (rank : 34)	θ value	0.47712 (rank : 17)
Query Neighborhood Hits	75	Target Neighborhood Hits	97	Shared Neighborhood Hits	5
SwissProt Accessions	Q53TS8, Q8NCN6, Q96LN4	Gene names	ALS2CR11
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 11 protein.

JIP1_MOUSE
NC score	0.065342 (rank : 35)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	75	Target Neighborhood Hits	259	Shared Neighborhood Hits	14
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

GAS7_HUMAN
NC score	0.064246 (rank : 36)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	75	Target Neighborhood Hits	258	Shared Neighborhood Hits	20
SwissProt Accessions	O60861, O43144	Gene names	GAS7, KIAA0394
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

WWTR1_HUMAN
NC score	0.061168 (rank : 37)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	75	Target Neighborhood Hits	76	Shared Neighborhood Hits	16
SwissProt Accessions	Q9GZV5, Q8N3P2, Q9Y3W6	Gene names	WWTR1, TAZ
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

SMUF1_MOUSE
NC score	0.055872 (rank : 38)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	75	Target Neighborhood Hits	142	Shared Neighborhood Hits	18
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

NUMBL_MOUSE
NC score	0.052608 (rank : 39)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	75	Target Neighborhood Hits	147	Shared Neighborhood Hits	11
SwissProt Accessions	O08919, Q6NVG8	Gene names	Numbl, Nbl
Domain Architecture
Description	Numb-like protein.

GAS7_MOUSE
NC score	0.052242 (rank : 40)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	75	Target Neighborhood Hits	259	Shared Neighborhood Hits	21
SwissProt Accessions	Q60780, Q9QY25, Q9QY26, Q9QY34	Gene names	Gas7
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

HUWE1_MOUSE
NC score	0.051725 (rank : 41)	θ value	1.06291 (rank : 25)
Query Neighborhood Hits	75	Target Neighborhood Hits	406	Shared Neighborhood Hits	18
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

SMRC2_HUMAN
NC score	0.046023 (rank : 42)	θ value	0.21417 (rank : 15)
Query Neighborhood Hits	75	Target Neighborhood Hits	499	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

SMRC2_MOUSE
NC score	0.042429 (rank : 43)	θ value	0.47712 (rank : 18)
Query Neighborhood Hits	75	Target Neighborhood Hits	487	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

CMGA_HUMAN
NC score	0.040177 (rank : 44)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	75	Target Neighborhood Hits	238	Shared Neighborhood Hits	8
SwissProt Accessions	P10645, Q96E84, Q96GL7, Q9BQB5	Gene names	CHGA
Domain Architecture
Description	Chromogranin A precursor (CgA) (Pituitary secretory protein I) (SP-I) [Contains: Vasostatin-1 (Vasostatin I); Vasostatin-2 (Vasostatin II); EA-92; ES-43; Pancreastatin; SS-18; WA-8; WE-14; LF-19; AL-11; GV-19; GR-44; ER-37].

IMMT_MOUSE
NC score	0.029827 (rank : 45)	θ value	1.06291 (rank : 26)
Query Neighborhood Hits	75	Target Neighborhood Hits	326	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CAQ8, Q66JS4, Q7TNE2, Q8C7V1, Q8CCI0, Q8CDA8, Q9D9F6	Gene names	Immt
Domain Architecture	No domain graphic available
Description	Mitochondrial inner membrane protein (Mitofilin).

KCT2_HUMAN
NC score	0.029740 (rank : 46)	θ value	1.81305 (rank : 32)
Query Neighborhood Hits	75	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NC54, Q9NRG2	Gene names	KCT2, C5orf15
Domain Architecture	No domain graphic available
Description	Keratinocytes-associated transmembrane protein 2 precursor.

PVRL2_MOUSE
NC score	0.022173 (rank : 47)	θ value	4.03905 (rank : 53)
Query Neighborhood Hits	75	Target Neighborhood Hits	242	Shared Neighborhood Hits	6
SwissProt Accessions	P32507, Q62096	Gene names	Pvrl2, Mph, Pvr, Pvs
Domain Architecture
Description	Poliovirus receptor-related protein 2 precursor (Murine herpesvirus entry protein B) (mHveB) (Nectin-2) (Poliovirus receptor homolog) (CD112 antigen).

IMMT_HUMAN
NC score	0.020967 (rank : 48)	θ value	5.27518 (rank : 59)
Query Neighborhood Hits	75	Target Neighborhood Hits	494	Shared Neighborhood Hits	10
SwissProt Accessions	Q16891, Q14539, Q15092, Q68D41, Q69HW5, Q6IBL0, Q7Z3X1, Q8TAJ5, Q9P0V2	Gene names	IMMT, HMP, PIG4
Domain Architecture	No domain graphic available
Description	Mitochondrial inner membrane protein (Mitofilin) (p87/89) (Proliferation-inducing gene 4 protein).

PVRL2_HUMAN
NC score	0.020290 (rank : 49)	θ value	6.88961 (rank : 67)
Query Neighborhood Hits	75	Target Neighborhood Hits	185	Shared Neighborhood Hits	5
SwissProt Accessions	Q92692, O75455, Q96J29	Gene names	PVRL2, HVEB, PRR2
Domain Architecture
Description	Poliovirus receptor-related protein 2 precursor (Herpes virus entry mediator B) (HveB) (Nectin-2) (CD112 antigen).

SPRL1_MOUSE
NC score	0.016707 (rank : 50)	θ value	2.36792 (rank : 42)
Query Neighborhood Hits	75	Target Neighborhood Hits	403	Shared Neighborhood Hits	11
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

TARA_HUMAN
NC score	0.015564 (rank : 51)	θ value	1.81305 (rank : 35)
Query Neighborhood Hits	75	Target Neighborhood Hits	1626	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

SPAG1_MOUSE
NC score	0.015527 (rank : 52)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	75	Target Neighborhood Hits	218	Shared Neighborhood Hits	3
SwissProt Accessions	Q80ZX8, Q8CCK7, Q9QZJ3, Q9QZJ4	Gene names	Spag1, Tpis
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 1 (Infertility-related sperm protein Spag-1) (TPR-containing protein involved in spermatogenesis) (TPIS).

KR104_HUMAN
NC score	0.015273 (rank : 53)	θ value	4.03905 (rank : 49)
Query Neighborhood Hits	75	Target Neighborhood Hits	313	Shared Neighborhood Hits	5
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

OLIG1_HUMAN
NC score	0.013028 (rank : 54)	θ value	4.03905 (rank : 50)
Query Neighborhood Hits	75	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TAK6, Q7RTS0	Gene names	OLIG1
Domain Architecture
Description	Oligodendrocyte transcription factor 1 (Oligo1).

PCNT_MOUSE
NC score	0.012646 (rank : 55)	θ value	0.62314 (rank : 19)
Query Neighborhood Hits	75	Target Neighborhood Hits	1207	Shared Neighborhood Hits	11
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

ANR41_HUMAN
NC score	0.012052 (rank : 56)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	75	Target Neighborhood Hits	332	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

UBP8_HUMAN
NC score	0.011677 (rank : 57)	θ value	5.27518 (rank : 62)
Query Neighborhood Hits	75	Target Neighborhood Hits	751	Shared Neighborhood Hits	15
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

RGS3_MOUSE
NC score	0.011512 (rank : 58)	θ value	4.03905 (rank : 54)
Query Neighborhood Hits	75	Target Neighborhood Hits	1621	Shared Neighborhood Hits	25
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

ANK2_HUMAN
NC score	0.011475 (rank : 59)	θ value	0.813845 (rank : 20)
Query Neighborhood Hits	75	Target Neighborhood Hits	1615	Shared Neighborhood Hits	24
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

TACC2_MOUSE
NC score	0.011024 (rank : 60)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	75	Target Neighborhood Hits	774	Shared Neighborhood Hits	12
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

K0528_MOUSE
NC score	0.010899 (rank : 61)	θ value	6.88961 (rank : 65)
Query Neighborhood Hits	75	Target Neighborhood Hits	102	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TPS5, Q3TQY6, Q6A052, Q80VA1, Q8C0U3, Q8CID5, Q9CS85	Gene names	Kiaa0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

OSBL8_HUMAN
NC score	0.010594 (rank : 62)	θ value	4.03905 (rank : 51)
Query Neighborhood Hits	75	Target Neighborhood Hits	289	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

ATS12_HUMAN
NC score	0.010450 (rank : 63)	θ value	1.06291 (rank : 24)
Query Neighborhood Hits	75	Target Neighborhood Hits	251	Shared Neighborhood Hits	6
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

UBP8_MOUSE
NC score	0.009989 (rank : 64)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	75	Target Neighborhood Hits	362	Shared Neighborhood Hits	14
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

DHX57_MOUSE
NC score	0.009428 (rank : 65)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	75	Target Neighborhood Hits	125	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P5D3, Q3TS93, Q6NZK4, Q6P1B4, Q8BI63, Q8BIA2, Q8R360	Gene names	Dhx57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

ARHGC_HUMAN
NC score	0.009192 (rank : 66)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	75	Target Neighborhood Hits	351	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

PGCB_HUMAN
NC score	0.009180 (rank : 67)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	75	Target Neighborhood Hits	478	Shared Neighborhood Hits	7
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

TAU_MOUSE
NC score	0.008970 (rank : 68)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	75	Target Neighborhood Hits	502	Shared Neighborhood Hits	9
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

LEO1_MOUSE
NC score	0.008697 (rank : 69)	θ value	6.88961 (rank : 66)
Query Neighborhood Hits	75	Target Neighborhood Hits	946	Shared Neighborhood Hits	12
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

ANK1_HUMAN
NC score	0.008444 (rank : 70)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	75	Target Neighborhood Hits	416	Shared Neighborhood Hits	5
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

BRD8_HUMAN
NC score	0.008151 (rank : 71)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	75	Target Neighborhood Hits	292	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

WDR24_MOUSE
NC score	0.007088 (rank : 72)	θ value	5.27518 (rank : 63)
Query Neighborhood Hits	75	Target Neighborhood Hits	286	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CFJ9	Gene names	Wdr24
Domain Architecture	No domain graphic available
Description	WD repeat protein 24.

MY18A_MOUSE
NC score	0.007035 (rank : 73)	θ value	0.813845 (rank : 21)
Query Neighborhood Hits	75	Target Neighborhood Hits	1989	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

CO5A2_HUMAN
NC score	0.005658 (rank : 74)	θ value	5.27518 (rank : 58)
Query Neighborhood Hits	75	Target Neighborhood Hits	760	Shared Neighborhood Hits	10
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

KR10B_HUMAN
NC score	0.005335 (rank : 75)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	75	Target Neighborhood Hits	269	Shared Neighborhood Hits	3
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

LAP4_MOUSE
NC score	0.004936 (rank : 76)	θ value	2.36792 (rank : 39)
Query Neighborhood Hits	75	Target Neighborhood Hits	590	Shared Neighborhood Hits	6
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

GRB10_HUMAN
NC score	0.004927 (rank : 77)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	75	Target Neighborhood Hits	147	Shared Neighborhood Hits	2
SwissProt Accessions	Q13322, O00427, O00701, O75222, Q92606, Q92907, Q92948	Gene names	GRB10, GRBIR, KIAA0207
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein) (Insulin receptor-binding protein GRB-IR).

MY18A_HUMAN
NC score	0.004724 (rank : 78)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	75	Target Neighborhood Hits	1929	Shared Neighborhood Hits	18
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

ABC8B_MOUSE
NC score	0.002681 (rank : 79)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	75	Target Neighborhood Hits	124	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K440, Q69ZY4, Q8BRQ1, Q9JL38	Gene names	Abca8b, Abca8, Kiaa0822
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 8-B.

PGFRA_HUMAN
NC score	0.002023 (rank : 80)	θ value	4.03905 (rank : 52)
Query Neighborhood Hits	75	Target Neighborhood Hits	980	Shared Neighborhood Hits	4
SwissProt Accessions	P16234, Q96KZ7	Gene names	PDGFRA
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

PGFRA_MOUSE
NC score	0.001821 (rank : 81)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	75	Target Neighborhood Hits	975	Shared Neighborhood Hits	4
SwissProt Accessions	P26618, Q62046	Gene names	Pdgfra
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

OBSCN_HUMAN
NC score	0.000920 (rank : 82)	θ value	2.36792 (rank : 41)
Query Neighborhood Hits	75	Target Neighborhood Hits	1931	Shared Neighborhood Hits	12
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).