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Network neighborhood for query Sequence : NEDD4_HUMAN

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NEDD4_HUMAN
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NED4L_HUMAN
θ value	0 (rank : 1)	NC score	0.991260 (rank : 3)
Query Neighborhood Hits	214	Target Neighborhood Hits	238	Shared Neighborhood Hits	189
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NED4L_MOUSE
θ value	0 (rank : 2)	NC score	0.990827 (rank : 4)
Query Neighborhood Hits	214	Target Neighborhood Hits	231	Shared Neighborhood Hits	188
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NEDD4_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	214	Target Neighborhood Hits	214	Shared Neighborhood Hits	214
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

NEDD4_MOUSE
θ value	0 (rank : 4)	NC score	0.996492 (rank : 2)
Query Neighborhood Hits	214	Target Neighborhood Hits	212	Shared Neighborhood Hits	193
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

ITCH_HUMAN
θ value	1.79534e-149 (rank : 5)	NC score	0.911498 (rank : 11)
Query Neighborhood Hits	214	Target Neighborhood Hits	162	Shared Neighborhood Hits	93
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

ITCH_MOUSE
θ value	5.22361e-149 (rank : 6)	NC score	0.917777 (rank : 8)
Query Neighborhood Hits	214	Target Neighborhood Hits	127	Shared Neighborhood Hits	87
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

WWP2_HUMAN
θ value	2.19465e-147 (rank : 7)	NC score	0.910956 (rank : 12)
Query Neighborhood Hits	214	Target Neighborhood Hits	177	Shared Neighborhood Hits	76
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

WWP2_MOUSE
θ value	2.42647e-146 (rank : 8)	NC score	0.914036 (rank : 10)
Query Neighborhood Hits	214	Target Neighborhood Hits	118	Shared Neighborhood Hits	80
SwissProt Accessions	Q9DBH0, Q8BTG4, Q923F6	Gene names	Wwp2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2).

WWP1_MOUSE
θ value	3.87392e-144 (rank : 9)	NC score	0.914846 (rank : 9)
Query Neighborhood Hits	214	Target Neighborhood Hits	138	Shared Neighborhood Hits	86
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

WWP1_HUMAN
θ value	3.27947e-143 (rank : 10)	NC score	0.906844 (rank : 13)
Query Neighborhood Hits	214	Target Neighborhood Hits	262	Shared Neighborhood Hits	85
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

SMUF2_HUMAN
θ value	2.689e-137 (rank : 11)	NC score	0.946445 (rank : 5)
Query Neighborhood Hits	214	Target Neighborhood Hits	142	Shared Neighborhood Hits	135
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

SMUF1_MOUSE
θ value	7.33985e-127 (rank : 12)	NC score	0.941622 (rank : 6)
Query Neighborhood Hits	214	Target Neighborhood Hits	142	Shared Neighborhood Hits	123
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

SMUF1_HUMAN
θ value	6.21357e-126 (rank : 13)	NC score	0.939658 (rank : 7)
Query Neighborhood Hits	214	Target Neighborhood Hits	135	Shared Neighborhood Hits	120
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

HUWE1_HUMAN
θ value	4.06505e-93 (rank : 14)	NC score	0.823868 (rank : 21)
Query Neighborhood Hits	214	Target Neighborhood Hits	443	Shared Neighborhood Hits	38
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

HUWE1_MOUSE
θ value	4.06505e-93 (rank : 15)	NC score	0.824997 (rank : 20)
Query Neighborhood Hits	214	Target Neighborhood Hits	406	Shared Neighborhood Hits	40
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

K0317_HUMAN
θ value	1.61343e-57 (rank : 16)	NC score	0.841558 (rank : 14)
Query Neighborhood Hits	214	Target Neighborhood Hits	46	Shared Neighborhood Hits	35
SwissProt Accessions	O15033, Q7LDY1, Q8IYY9	Gene names	KIAA0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

K0317_MOUSE
θ value	2.10721e-57 (rank : 17)	NC score	0.841314 (rank : 15)
Query Neighborhood Hits	214	Target Neighborhood Hits	43	Shared Neighborhood Hits	35
SwissProt Accessions	Q8CHG5, Q6P9Q1, Q80YC4, Q8C5W5	Gene names	Kiaa0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

UBE3A_HUMAN
θ value	1.32293e-51 (rank : 18)	NC score	0.831037 (rank : 18)
Query Neighborhood Hits	214	Target Neighborhood Hits	49	Shared Neighborhood Hits	33
SwissProt Accessions	Q05086, P78355, Q93066, Q9UEP4, Q9UEP5, Q9UEP6, Q9UEP7, Q9UEP8, Q9UEP9	Gene names	UBE3A, E6AP
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Oncogenic protein-associated protein E6-AP) (Human papillomavirus E6-associated protein) (NY-REN-54 antigen).

HECD2_HUMAN
θ value	7.25919e-50 (rank : 19)	NC score	0.832610 (rank : 17)
Query Neighborhood Hits	214	Target Neighborhood Hits	41	Shared Neighborhood Hits	34
SwissProt Accessions	Q5U5R9, Q5VZ97, Q5VZ99, Q8TCP5	Gene names	HECTD2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

HECD2_MOUSE
θ value	9.48078e-50 (rank : 20)	NC score	0.835005 (rank : 16)
Query Neighborhood Hits	214	Target Neighborhood Hits	38	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CDU6, Q8CBQ9	Gene names	Hectd2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

UBE3A_MOUSE
θ value	3.04986e-48 (rank : 21)	NC score	0.825932 (rank : 19)
Query Neighborhood Hits	214	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	O08759, P97482	Gene names	Ube3a
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (Oncogenic protein- associated protein E6-AP).

UBE3C_HUMAN
θ value	1.67352e-46 (rank : 22)	NC score	0.819748 (rank : 22)
Query Neighborhood Hits	214	Target Neighborhood Hits	51	Shared Neighborhood Hits	35
SwissProt Accessions	Q15386, Q8TC15, Q96CR4, Q9UDU3	Gene names	UBE3C, KIAA0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

UBE3C_MOUSE
θ value	3.72821e-46 (rank : 23)	NC score	0.818338 (rank : 23)
Query Neighborhood Hits	214	Target Neighborhood Hits	48	Shared Neighborhood Hits	35
SwissProt Accessions	Q80U95, Q8BQZ6, Q8C7W6, Q8CDJ1, Q8VDL5	Gene names	Ube3c, Kiaa0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

HERC3_HUMAN
θ value	1.19932e-44 (rank : 24)	NC score	0.690178 (rank : 26)
Query Neighborhood Hits	214	Target Neighborhood Hits	62	Shared Neighborhood Hits	33
SwissProt Accessions	Q15034	Gene names	HERC3, KIAA0032
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain protein 3.

HERC5_HUMAN
θ value	3.05695e-40 (rank : 25)	NC score	0.697252 (rank : 25)
Query Neighborhood Hits	214	Target Neighborhood Hits	66	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UII4	Gene names	HERC5, CEB1, CEBP1
Domain Architecture
Description	HECT domain and RCC1-like domain-containing protein 5 (Cyclin-E- binding protein 1).

HERC2_MOUSE
θ value	1.33217e-27 (rank : 26)	NC score	0.582219 (rank : 31)
Query Neighborhood Hits	214	Target Neighborhood Hits	167	Shared Neighborhood Hits	37
SwissProt Accessions	Q4U2R1, O88473, Q3TRJ8, Q3TS47, Q3TST2, Q3UFQ6, Q3URH7, Q5DU32, Q7TPR5, Q80VV7, Q9QYT1, Q9Z168, Q9Z171	Gene names	Herc2, jdf2, Kiaa0393, rjs
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

HERC2_HUMAN
θ value	5.06226e-27 (rank : 27)	NC score	0.578393 (rank : 32)
Query Neighborhood Hits	214	Target Neighborhood Hits	163	Shared Neighborhood Hits	37
SwissProt Accessions	O95714, Q86SV7, Q86SV8, Q86SV9, Q86YY3, Q86YY4, Q86YY5, Q86YY6, Q86YY7, Q86YY8, Q86YY9, Q86YZ0, Q86YZ1	Gene names	HERC2
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

TRIPC_HUMAN
θ value	1.37858e-24 (rank : 28)	NC score	0.740141 (rank : 24)
Query Neighborhood Hits	214	Target Neighborhood Hits	319	Shared Neighborhood Hits	39
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

EDD1_HUMAN
θ value	7.82807e-20 (rank : 29)	NC score	0.634484 (rank : 30)
Query Neighborhood Hits	214	Target Neighborhood Hits	170	Shared Neighborhood Hits	33
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

EDD1_MOUSE
θ value	7.82807e-20 (rank : 30)	NC score	0.635845 (rank : 29)
Query Neighborhood Hits	214	Target Neighborhood Hits	167	Shared Neighborhood Hits	34
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

HECD1_HUMAN
θ value	1.24977e-17 (rank : 31)	NC score	0.523249 (rank : 33)
Query Neighborhood Hits	214	Target Neighborhood Hits	371	Shared Neighborhood Hits	35
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

YAP1_MOUSE
θ value	8.10077e-17 (rank : 32)	NC score	0.520319 (rank : 34)
Query Neighborhood Hits	214	Target Neighborhood Hits	96	Shared Neighborhood Hits	51
SwissProt Accessions	P46938, Q52KJ5	Gene names	Yap1, Yap, Yap65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

HECD3_MOUSE
θ value	1.058e-16 (rank : 33)	NC score	0.658858 (rank : 27)
Query Neighborhood Hits	214	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	Q3U487, Q3TN76, Q641P3, Q8BQ74, Q8R1L6	Gene names	Hectd3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

HECD3_HUMAN
θ value	2.35696e-16 (rank : 34)	NC score	0.654136 (rank : 28)
Query Neighborhood Hits	214	Target Neighborhood Hits	49	Shared Neighborhood Hits	33
SwissProt Accessions	Q5T447, Q5T448, Q9H783	Gene names	HECTD3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

MAGI1_HUMAN
θ value	1.33837e-11 (rank : 35)	NC score	0.281499 (rank : 89)
Query Neighborhood Hits	214	Target Neighborhood Hits	388	Shared Neighborhood Hits	52
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

WWC1_HUMAN
θ value	1.33837e-11 (rank : 36)	NC score	0.427514 (rank : 38)
Query Neighborhood Hits	214	Target Neighborhood Hits	290	Shared Neighborhood Hits	59
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

WWC1_MOUSE
θ value	1.33837e-11 (rank : 37)	NC score	0.440653 (rank : 37)
Query Neighborhood Hits	214	Target Neighborhood Hits	290	Shared Neighborhood Hits	62
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

MAGI1_MOUSE
θ value	1.74796e-11 (rank : 38)	NC score	0.281108 (rank : 90)
Query Neighborhood Hits	214	Target Neighborhood Hits	403	Shared Neighborhood Hits	53
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

MAGI2_MOUSE
θ value	6.64225e-11 (rank : 39)	NC score	0.300823 (rank : 80)
Query Neighborhood Hits	214	Target Neighborhood Hits	370	Shared Neighborhood Hits	50
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

MAGI2_HUMAN
θ value	1.47974e-10 (rank : 40)	NC score	0.286712 (rank : 88)
Query Neighborhood Hits	214	Target Neighborhood Hits	373	Shared Neighborhood Hits	45
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

SYT7_MOUSE
θ value	2.52405e-10 (rank : 41)	NC score	0.359168 (rank : 47)
Query Neighborhood Hits	214	Target Neighborhood Hits	137	Shared Neighborhood Hits	118
SwissProt Accessions	Q9R0N7	Gene names	Syt7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

WWOX_HUMAN
θ value	2.52405e-10 (rank : 42)	NC score	0.359781 (rank : 46)
Query Neighborhood Hits	214	Target Neighborhood Hits	115	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NZC7, Q5MYT5, Q96KM3, Q96RF2, Q9BTT8, Q9NPC9, Q9NRF4, Q9NRF5, Q9NRF6, Q9NRK1, Q9NZC5	Gene names	WWOX, FOR, WOX1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-) (Fragile site FRA16D oxidoreductase).

WWOX_MOUSE
θ value	2.52405e-10 (rank : 43)	NC score	0.356658 (rank : 48)
Query Neighborhood Hits	214	Target Neighborhood Hits	118	Shared Neighborhood Hits	48
SwissProt Accessions	Q91WL8, Q8C8J6, Q920Y2, Q9D2B3, Q9D339, Q9JLF5	Gene names	Wwox, Wox1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-).

KPCA_MOUSE
θ value	7.34386e-10 (rank : 44)	NC score	0.108280 (rank : 177)
Query Neighborhood Hits	214	Target Neighborhood Hits	1067	Shared Neighborhood Hits	121
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KPCG_MOUSE
θ value	7.34386e-10 (rank : 45)	NC score	0.113325 (rank : 169)
Query Neighborhood Hits	214	Target Neighborhood Hits	1123	Shared Neighborhood Hits	119
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

SYT9_MOUSE
θ value	7.34386e-10 (rank : 46)	NC score	0.346262 (rank : 58)
Query Neighborhood Hits	214	Target Neighborhood Hits	148	Shared Neighborhood Hits	122
SwissProt Accessions	Q9R0N9, Q8C280	Gene names	Syt9, Syt5
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX) (Synaptotagmin V).

SYT7_HUMAN
θ value	9.59137e-10 (rank : 47)	NC score	0.360183 (rank : 45)
Query Neighborhood Hits	214	Target Neighborhood Hits	137	Shared Neighborhood Hits	118
SwissProt Accessions	O43581	Gene names	SYT7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

KPCA_HUMAN
θ value	1.25267e-09 (rank : 48)	NC score	0.110617 (rank : 175)
Query Neighborhood Hits	214	Target Neighborhood Hits	1070	Shared Neighborhood Hits	121
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KPCG_HUMAN
θ value	1.25267e-09 (rank : 49)	NC score	0.112557 (rank : 172)
Query Neighborhood Hits	214	Target Neighborhood Hits	1126	Shared Neighborhood Hits	119
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

PA24B_MOUSE
θ value	1.25267e-09 (rank : 50)	NC score	0.253488 (rank : 105)
Query Neighborhood Hits	214	Target Neighborhood Hits	102	Shared Neighborhood Hits	82
SwissProt Accessions	Q4QQM1, Q80VV8, Q91W88	Gene names	Pla2g4b
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

SYT10_MOUSE
θ value	2.13673e-09 (rank : 51)	NC score	0.349848 (rank : 53)
Query Neighborhood Hits	214	Target Neighborhood Hits	133	Shared Neighborhood Hits	119
SwissProt Accessions	Q9R0N4	Gene names	Syt10
Domain Architecture
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

UN13B_HUMAN
θ value	2.13673e-09 (rank : 52)	NC score	0.298702 (rank : 82)
Query Neighborhood Hits	214	Target Neighborhood Hits	217	Shared Neighborhood Hits	106
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

UN13B_MOUSE
θ value	2.79066e-09 (rank : 53)	NC score	0.300600 (rank : 81)
Query Neighborhood Hits	214	Target Neighborhood Hits	210	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

RASL2_HUMAN
θ value	4.76016e-09 (rank : 54)	NC score	0.342220 (rank : 70)
Query Neighborhood Hits	214	Target Neighborhood Hits	161	Shared Neighborhood Hits	112
SwissProt Accessions	O43374, O60286, Q86UW3, Q96QU0	Gene names	RASA4, CAPRI, GAPL, KIAA0538
Domain Architecture
Description	Ras GTPase-activating protein 4 (RasGAP-activating-like protein 2) (Calcium-promoted Ras inactivator).

SYT9_HUMAN
θ value	8.11959e-09 (rank : 55)	NC score	0.344763 (rank : 60)
Query Neighborhood Hits	214	Target Neighborhood Hits	144	Shared Neighborhood Hits	121
SwissProt Accessions	Q86SS6	Gene names	SYT9
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX).

DOC2A_MOUSE
θ value	1.06045e-08 (rank : 56)	NC score	0.374000 (rank : 40)
Query Neighborhood Hits	214	Target Neighborhood Hits	140	Shared Neighborhood Hits	121
SwissProt Accessions	Q7TNF0	Gene names	Doc2a
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha).

RASL1_HUMAN
θ value	1.06045e-08 (rank : 57)	NC score	0.320969 (rank : 74)
Query Neighborhood Hits	214	Target Neighborhood Hits	142	Shared Neighborhood Hits	101
SwissProt Accessions	O95294, Q52M03, Q96CC7	Gene names	RASAL1, RASAL
Domain Architecture
Description	RasGAP-activating-like protein 1.

SYT10_HUMAN
θ value	1.38499e-08 (rank : 58)	NC score	0.350901 (rank : 51)
Query Neighborhood Hits	214	Target Neighborhood Hits	134	Shared Neighborhood Hits	119
SwissProt Accessions	Q6XYQ8	Gene names	SYT10
Domain Architecture	No domain graphic available
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

SYT3_MOUSE
θ value	1.38499e-08 (rank : 59)	NC score	0.345231 (rank : 59)
Query Neighborhood Hits	214	Target Neighborhood Hits	147	Shared Neighborhood Hits	117
SwissProt Accessions	O35681, P97791, Q80WV1	Gene names	Syt3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

RASL1_MOUSE
θ value	1.80886e-08 (rank : 60)	NC score	0.309596 (rank : 79)
Query Neighborhood Hits	214	Target Neighborhood Hits	148	Shared Neighborhood Hits	100
SwissProt Accessions	Q9Z268	Gene names	Rasal1, Rasal
Domain Architecture
Description	RasGAP-activating-like protein 1.

SYT6_MOUSE
θ value	1.80886e-08 (rank : 61)	NC score	0.344459 (rank : 62)
Query Neighborhood Hits	214	Target Neighborhood Hits	132	Shared Neighborhood Hits	118
SwissProt Accessions	Q9R0N8	Gene names	Syt6
Domain Architecture
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

UN13A_HUMAN
θ value	1.80886e-08 (rank : 62)	NC score	0.295135 (rank : 83)
Query Neighborhood Hits	214	Target Neighborhood Hits	285	Shared Neighborhood Hits	105
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

SYT3_HUMAN
θ value	2.36244e-08 (rank : 63)	NC score	0.344607 (rank : 61)
Query Neighborhood Hits	214	Target Neighborhood Hits	145	Shared Neighborhood Hits	117
SwissProt Accessions	Q9BQG1, Q8N5Z1, Q8N640	Gene names	SYT3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

SYT6_HUMAN
θ value	4.0297e-08 (rank : 64)	NC score	0.342970 (rank : 68)
Query Neighborhood Hits	214	Target Neighborhood Hits	138	Shared Neighborhood Hits	117
SwissProt Accessions	Q5T7P8	Gene names	SYT6
Domain Architecture	No domain graphic available
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

DOC2B_HUMAN
θ value	6.87365e-08 (rank : 65)	NC score	0.368151 (rank : 41)
Query Neighborhood Hits	214	Target Neighborhood Hits	150	Shared Neighborhood Hits	121
SwissProt Accessions	Q14184	Gene names	DOC2B
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

DOC2G_MOUSE
θ value	6.87365e-08 (rank : 66)	NC score	0.344453 (rank : 63)
Query Neighborhood Hits	214	Target Neighborhood Hits	125	Shared Neighborhood Hits	106
SwissProt Accessions	Q9ESN1, Q6P8R8	Gene names	Doc2g
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein gamma (Doc2-gamma).

SAV1_MOUSE
θ value	6.87365e-08 (rank : 67)	NC score	0.473214 (rank : 36)
Query Neighborhood Hits	214	Target Neighborhood Hits	48	Shared Neighborhood Hits	41
SwissProt Accessions	Q8VEB2, Q9D9N9, Q9ER46	Gene names	Sav1, Ww45, Wwp3
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (mWW45).

DOC2B_MOUSE
θ value	8.97725e-08 (rank : 68)	NC score	0.366578 (rank : 43)
Query Neighborhood Hits	214	Target Neighborhood Hits	169	Shared Neighborhood Hits	122
SwissProt Accessions	P70169, Q6NXK3	Gene names	Doc2b
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

PA24B_HUMAN
θ value	1.53129e-07 (rank : 69)	NC score	0.218451 (rank : 118)
Query Neighborhood Hits	214	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	O95712, Q59GF9, Q8TB10, Q9UKV7	Gene names	PLA2G4B
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

SAV1_HUMAN
θ value	1.53129e-07 (rank : 70)	NC score	0.473618 (rank : 35)
Query Neighborhood Hits	214	Target Neighborhood Hits	51	Shared Neighborhood Hits	43
SwissProt Accessions	Q9H4B6, Q6IA58, Q9H949, Q9HAK9	Gene names	SAV1, WW45
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (hWW45).

SYT5_HUMAN
θ value	1.53129e-07 (rank : 71)	NC score	0.349670 (rank : 54)
Query Neighborhood Hits	214	Target Neighborhood Hits	138	Shared Neighborhood Hits	120
SwissProt Accessions	O00445, Q86X72	Gene names	SYT5
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV).

RP3A_HUMAN
θ value	1.99992e-07 (rank : 72)	NC score	0.348737 (rank : 55)
Query Neighborhood Hits	214	Target Neighborhood Hits	305	Shared Neighborhood Hits	122
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

RP3A_MOUSE
θ value	2.61198e-07 (rank : 73)	NC score	0.343199 (rank : 66)
Query Neighborhood Hits	214	Target Neighborhood Hits	510	Shared Neighborhood Hits	121
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

DOC2A_HUMAN
θ value	4.45536e-07 (rank : 74)	NC score	0.367919 (rank : 42)
Query Neighborhood Hits	214	Target Neighborhood Hits	144	Shared Neighborhood Hits	119
SwissProt Accessions	Q14183, Q6P4G4, Q7Z5G0, Q8IVX0	Gene names	DOC2A
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha) (Doc2).

PCLO_HUMAN
θ value	4.45536e-07 (rank : 75)	NC score	0.244793 (rank : 106)
Query Neighborhood Hits	214	Target Neighborhood Hits	2046	Shared Neighborhood Hits	139
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

KPCB_HUMAN
θ value	7.59969e-07 (rank : 76)	NC score	0.104830 (rank : 180)
Query Neighborhood Hits	214	Target Neighborhood Hits	1121	Shared Neighborhood Hits	121
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCB_MOUSE
θ value	7.59969e-07 (rank : 77)	NC score	0.106354 (rank : 178)
Query Neighborhood Hits	214	Target Neighborhood Hits	1117	Shared Neighborhood Hits	121
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

SYT2_HUMAN
θ value	1.29631e-06 (rank : 78)	NC score	0.342982 (rank : 67)
Query Neighborhood Hits	214	Target Neighborhood Hits	142	Shared Neighborhood Hits	121
SwissProt Accessions	Q8N9I0, Q496K5, Q8NBE5	Gene names	SYT2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT2_MOUSE
θ value	1.29631e-06 (rank : 79)	NC score	0.343343 (rank : 65)
Query Neighborhood Hits	214	Target Neighborhood Hits	143	Shared Neighborhood Hits	121
SwissProt Accessions	P46097, Q8R0E1	Gene names	Syt2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

BAG3_MOUSE
θ value	1.69304e-06 (rank : 80)	NC score	0.290936 (rank : 85)
Query Neighborhood Hits	214	Target Neighborhood Hits	513	Shared Neighborhood Hits	43
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

PCLO_MOUSE
θ value	1.69304e-06 (rank : 81)	NC score	0.234806 (rank : 112)
Query Neighborhood Hits	214	Target Neighborhood Hits	2275	Shared Neighborhood Hits	144
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PKHA5_HUMAN
θ value	1.69304e-06 (rank : 82)	NC score	0.255239 (rank : 104)
Query Neighborhood Hits	214	Target Neighborhood Hits	455	Shared Neighborhood Hits	44
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

ITSN1_HUMAN
θ value	2.21117e-06 (rank : 83)	NC score	0.112639 (rank : 170)
Query Neighborhood Hits	214	Target Neighborhood Hits	1757	Shared Neighborhood Hits	111
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN1_MOUSE
θ value	2.21117e-06 (rank : 84)	NC score	0.112613 (rank : 171)
Query Neighborhood Hits	214	Target Neighborhood Hits	1669	Shared Neighborhood Hits	112
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

SYT1_HUMAN
θ value	2.21117e-06 (rank : 85)	NC score	0.347023 (rank : 56)
Query Neighborhood Hits	214	Target Neighborhood Hits	150	Shared Neighborhood Hits	121
SwissProt Accessions	P21579	Gene names	SYT1, SYT
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT1_MOUSE
θ value	2.21117e-06 (rank : 86)	NC score	0.347018 (rank : 57)
Query Neighborhood Hits	214	Target Neighborhood Hits	150	Shared Neighborhood Hits	121
SwissProt Accessions	P46096	Gene names	Syt1
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

BAG3_HUMAN
θ value	2.88788e-06 (rank : 87)	NC score	0.336130 (rank : 73)
Query Neighborhood Hits	214	Target Neighborhood Hits	314	Shared Neighborhood Hits	41
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

FA62A_MOUSE
θ value	4.92598e-06 (rank : 88)	NC score	0.360576 (rank : 44)
Query Neighborhood Hits	214	Target Neighborhood Hits	155	Shared Neighborhood Hits	119
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

SYT5_MOUSE
θ value	4.92598e-06 (rank : 89)	NC score	0.342964 (rank : 69)
Query Neighborhood Hits	214	Target Neighborhood Hits	140	Shared Neighborhood Hits	118
SwissProt Accessions	Q9R0N5	Gene names	Syt5, Syt9
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV) (Synaptotagmin IX).

ITSN2_HUMAN
θ value	8.40245e-06 (rank : 90)	NC score	0.128872 (rank : 161)
Query Neighborhood Hits	214	Target Neighborhood Hits	1173	Shared Neighborhood Hits	98
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

ITSN2_MOUSE
θ value	8.40245e-06 (rank : 91)	NC score	0.120863 (rank : 164)
Query Neighborhood Hits	214	Target Neighborhood Hits	1371	Shared Neighborhood Hits	101
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

FA62A_HUMAN
θ value	1.09739e-05 (rank : 92)	NC score	0.343386 (rank : 64)
Query Neighborhood Hits	214	Target Neighborhood Hits	168	Shared Neighborhood Hits	117
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

SYTL2_HUMAN
θ value	1.87187e-05 (rank : 93)	NC score	0.289886 (rank : 86)
Query Neighborhood Hits	214	Target Neighborhood Hits	248	Shared Neighborhood Hits	95
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

PA24D_MOUSE
θ value	4.1701e-05 (rank : 94)	NC score	0.258006 (rank : 102)
Query Neighborhood Hits	214	Target Neighborhood Hits	100	Shared Neighborhood Hits	89
SwissProt Accessions	Q50L43, Q3TJC5	Gene names	Pla2g4d
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

SYTL2_MOUSE
θ value	4.1701e-05 (rank : 95)	NC score	0.289823 (rank : 87)
Query Neighborhood Hits	214	Target Neighborhood Hits	253	Shared Neighborhood Hits	100
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

WWTR1_HUMAN
θ value	5.44631e-05 (rank : 96)	NC score	0.351637 (rank : 50)
Query Neighborhood Hits	214	Target Neighborhood Hits	76	Shared Neighborhood Hits	41
SwissProt Accessions	Q9GZV5, Q8N3P2, Q9Y3W6	Gene names	WWTR1, TAZ
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

WWTR1_MOUSE
θ value	5.44631e-05 (rank : 97)	NC score	0.355080 (rank : 49)
Query Neighborhood Hits	214	Target Neighborhood Hits	54	Shared Neighborhood Hits	39
SwissProt Accessions	Q9EPK5, Q99KI4	Gene names	Wwtr1, Taz
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

SYT4_MOUSE
θ value	7.1131e-05 (rank : 98)	NC score	0.313041 (rank : 75)
Query Neighborhood Hits	214	Target Neighborhood Hits	123	Shared Neighborhood Hits	104
SwissProt Accessions	P40749, Q3UFC1, Q8BGH3, Q8BRL6	Gene names	Syt4, Syt3
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

PA24E_MOUSE
θ value	9.29e-05 (rank : 99)	NC score	0.210356 (rank : 121)
Query Neighborhood Hits	214	Target Neighborhood Hits	95	Shared Neighborhood Hits	80
SwissProt Accessions	Q50L42, Q8BX44	Gene names	Pla2g4e
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

SYT4_HUMAN
θ value	0.000121331 (rank : 100)	NC score	0.309974 (rank : 78)
Query Neighborhood Hits	214	Target Neighborhood Hits	121	Shared Neighborhood Hits	106
SwissProt Accessions	Q9H2B2, Q9P2K4	Gene names	SYT4, KIAA1342
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

YAP1_HUMAN
θ value	0.00020696 (rank : 101)	NC score	0.350602 (rank : 52)
Query Neighborhood Hits	214	Target Neighborhood Hits	173	Shared Neighborhood Hits	51
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

UN13D_HUMAN
θ value	0.000270298 (rank : 102)	NC score	0.294176 (rank : 84)
Query Neighborhood Hits	214	Target Neighborhood Hits	117	Shared Neighborhood Hits	94
SwissProt Accessions	Q70J99, Q9H7K5	Gene names	UNC13D
Domain Architecture	No domain graphic available
Description	Unc-13 homolog D (Munc13-4).

SYTL1_MOUSE
θ value	0.00035302 (rank : 103)	NC score	0.269827 (rank : 98)
Query Neighborhood Hits	214	Target Neighborhood Hits	314	Shared Neighborhood Hits	84
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

PA24D_HUMAN
θ value	0.000461057 (rank : 104)	NC score	0.234438 (rank : 113)
Query Neighborhood Hits	214	Target Neighborhood Hits	97	Shared Neighborhood Hits	83
SwissProt Accessions	Q86XP0, Q8N176	Gene names	PLA2G4D
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

SYT11_HUMAN
θ value	0.000602161 (rank : 105)	NC score	0.310444 (rank : 77)
Query Neighborhood Hits	214	Target Neighborhood Hits	113	Shared Neighborhood Hits	99
SwissProt Accessions	Q9BT88, Q14998, Q68CT5, Q8IXU3, Q96SU2	Gene names	SYT11, KIAA0080
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

SYT11_MOUSE
θ value	0.000602161 (rank : 106)	NC score	0.310505 (rank : 76)
Query Neighborhood Hits	214	Target Neighborhood Hits	116	Shared Neighborhood Hits	101
SwissProt Accessions	Q9R0N3	Gene names	Syt11
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

RHG12_MOUSE
θ value	0.00102713 (rank : 107)	NC score	0.102934 (rank : 181)
Query Neighborhood Hits	214	Target Neighborhood Hits	204	Shared Neighborhood Hits	33
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

PA24E_HUMAN
θ value	0.00134147 (rank : 108)	NC score	0.197056 (rank : 130)
Query Neighborhood Hits	214	Target Neighborhood Hits	89	Shared Neighborhood Hits	76
SwissProt Accessions	Q3MJ16, Q6ZSC0	Gene names	PLA2G4E
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

PRP40_HUMAN
θ value	0.00134147 (rank : 109)	NC score	0.187482 (rank : 135)
Query Neighborhood Hits	214	Target Neighborhood Hits	442	Shared Neighborhood Hits	41
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

PRP40_MOUSE
θ value	0.00134147 (rank : 110)	NC score	0.186617 (rank : 136)
Query Neighborhood Hits	214	Target Neighborhood Hits	447	Shared Neighborhood Hits	42
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

PIN1_HUMAN
θ value	0.00228821 (rank : 111)	NC score	0.340040 (rank : 72)
Query Neighborhood Hits	214	Target Neighborhood Hits	59	Shared Neighborhood Hits	44
SwissProt Accessions	Q13526	Gene names	PIN1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

PIN1_MOUSE
θ value	0.00228821 (rank : 112)	NC score	0.342198 (rank : 71)
Query Neighborhood Hits	214	Target Neighborhood Hits	60	Shared Neighborhood Hits	46
SwissProt Accessions	Q9QUR7, Q543B3	Gene names	Pin1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

SYTL1_HUMAN
θ value	0.00228821 (rank : 113)	NC score	0.275798 (rank : 92)
Query Neighborhood Hits	214	Target Neighborhood Hits	227	Shared Neighborhood Hits	91
SwissProt Accessions	Q8IYJ3, Q96BB6, Q96GU6, Q96S89, Q96SI0	Gene names	SYTL1, SLP1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1) (SB146).

SYTL5_HUMAN
θ value	0.00228821 (rank : 114)	NC score	0.270347 (rank : 97)
Query Neighborhood Hits	214	Target Neighborhood Hits	237	Shared Neighborhood Hits	107
SwissProt Accessions	Q8TDW5	Gene names	SYTL5, SLP5
Domain Architecture
Description	Synaptotagmin-like protein 5.

K1333_MOUSE
θ value	0.00298849 (rank : 115)	NC score	0.095465 (rank : 185)
Query Neighborhood Hits	214	Target Neighborhood Hits	53	Shared Neighborhood Hits	13
SwissProt Accessions	Q5RJY2, Q6ZPT7, Q8BNA4	Gene names	Kiaa1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

RIMS2_MOUSE
θ value	0.00298849 (rank : 116)	NC score	0.259694 (rank : 101)
Query Neighborhood Hits	214	Target Neighborhood Hits	376	Shared Neighborhood Hits	114
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

K1333_HUMAN
θ value	0.00390308 (rank : 117)	NC score	0.062952 (rank : 211)
Query Neighborhood Hits	214	Target Neighborhood Hits	50	Shared Neighborhood Hits	9
SwissProt Accessions	Q7L622, Q9BVR2, Q9H9E9, Q9NXC0, Q9P2L3	Gene names	KIAA1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

APBB2_HUMAN
θ value	0.00509761 (rank : 118)	NC score	0.159203 (rank : 145)
Query Neighborhood Hits	214	Target Neighborhood Hits	96	Shared Neighborhood Hits	31
SwissProt Accessions	Q92870, Q8IUI6	Gene names	APBB2, FE65L, FE65L1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2 (Fe65-like protein).

APBB2_MOUSE
θ value	0.00509761 (rank : 119)	NC score	0.150765 (rank : 147)
Query Neighborhood Hits	214	Target Neighborhood Hits	88	Shared Neighborhood Hits	27
SwissProt Accessions	Q9DBR4, Q6DFX8	Gene names	Apbb2
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2.

BAIP3_MOUSE
θ value	0.00509761 (rank : 120)	NC score	0.271537 (rank : 96)
Query Neighborhood Hits	214	Target Neighborhood Hits	112	Shared Neighborhood Hits	94
SwissProt Accessions	Q80TT2, Q6RUT4	Gene names	Baiap3, Gm937, Kiaa0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

MYOF_HUMAN
θ value	0.00509761 (rank : 121)	NC score	0.229951 (rank : 114)
Query Neighborhood Hits	214	Target Neighborhood Hits	147	Shared Neighborhood Hits	108
SwissProt Accessions	Q9NZM1, Q9HBU3, Q9NZM0, Q9ULL3, Q9Y4U4	Gene names	FER1L3, KIAA1207, MYOF
Domain Architecture
Description	Myoferlin (Fer-1-like protein 3).

RIMS2_HUMAN
θ value	0.00509761 (rank : 122)	NC score	0.261996 (rank : 100)
Query Neighborhood Hits	214	Target Neighborhood Hits	342	Shared Neighborhood Hits	113
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

PA24F_MOUSE
θ value	0.00665767 (rank : 123)	NC score	0.174337 (rank : 138)
Query Neighborhood Hits	214	Target Neighborhood Hits	93	Shared Neighborhood Hits	71
SwissProt Accessions	Q50L41, Q80VQ8, Q80VV9	Gene names	Pla2g4f
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

PINL_HUMAN
θ value	0.00665767 (rank : 124)	NC score	0.392242 (rank : 39)
Query Neighborhood Hits	214	Target Neighborhood Hits	47	Shared Neighborhood Hits	43
SwissProt Accessions	O15428	Gene names	PIN1L
Domain Architecture
Description	PIN1-like protein.

RASA2_HUMAN
θ value	0.00665767 (rank : 125)	NC score	0.202959 (rank : 125)
Query Neighborhood Hits	214	Target Neighborhood Hits	157	Shared Neighborhood Hits	78
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

GAS7_HUMAN
θ value	0.00869519 (rank : 126)	NC score	0.229232 (rank : 115)
Query Neighborhood Hits	214	Target Neighborhood Hits	258	Shared Neighborhood Hits	50
SwissProt Accessions	O60861, O43144	Gene names	GAS7, KIAA0394
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

PLCD1_HUMAN
θ value	0.00869519 (rank : 127)	NC score	0.114560 (rank : 168)
Query Neighborhood Hits	214	Target Neighborhood Hits	93	Shared Neighborhood Hits	55
SwissProt Accessions	P51178	Gene names	PLCD1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

GAS7_MOUSE
θ value	0.0113563 (rank : 128)	NC score	0.227169 (rank : 116)
Query Neighborhood Hits	214	Target Neighborhood Hits	259	Shared Neighborhood Hits	49
SwissProt Accessions	Q60780, Q9QY25, Q9QY26, Q9QY34	Gene names	Gas7
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

RASA2_MOUSE
θ value	0.0113563 (rank : 129)	NC score	0.201053 (rank : 127)
Query Neighborhood Hits	214	Target Neighborhood Hits	159	Shared Neighborhood Hits	79
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

DMD_HUMAN
θ value	0.0148317 (rank : 130)	NC score	0.052258 (rank : 217)
Query Neighborhood Hits	214	Target Neighborhood Hits	1135	Shared Neighborhood Hits	43
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

DMD_MOUSE
θ value	0.0148317 (rank : 131)	NC score	0.047083 (rank : 219)
Query Neighborhood Hits	214	Target Neighborhood Hits	1111	Shared Neighborhood Hits	44
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

OTOF_HUMAN
θ value	0.0148317 (rank : 132)	NC score	0.198096 (rank : 128)
Query Neighborhood Hits	214	Target Neighborhood Hits	168	Shared Neighborhood Hits	97
SwissProt Accessions	Q9HC10, Q9HC08, Q9HC09, Q9Y650	Gene names	OTOF, FER1L2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

P3C2B_HUMAN
θ value	0.0148317 (rank : 133)	NC score	0.163516 (rank : 142)
Query Neighborhood Hits	214	Target Neighborhood Hits	148	Shared Neighborhood Hits	78
SwissProt Accessions	O00750, O95666, Q5SW99	Gene names	PIK3C2B
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-beta) (PtdIns-3-kinase C2 beta) (PI3K-C2beta) (C2-PI3K).

RIMS1_HUMAN
θ value	0.0148317 (rank : 134)	NC score	0.235665 (rank : 111)
Query Neighborhood Hits	214	Target Neighborhood Hits	437	Shared Neighborhood Hits	97
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

SYTL4_HUMAN
θ value	0.0148317 (rank : 135)	NC score	0.279754 (rank : 91)
Query Neighborhood Hits	214	Target Neighborhood Hits	138	Shared Neighborhood Hits	89
SwissProt Accessions	Q96C24, Q5H9J3, Q5JPG8, Q8N9P4, Q9H4R0, Q9H4R1	Gene names	SYTL4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

BAIP3_HUMAN
θ value	0.0193708 (rank : 136)	NC score	0.262022 (rank : 99)
Query Neighborhood Hits	214	Target Neighborhood Hits	108	Shared Neighborhood Hits	83
SwissProt Accessions	O94812, O94839, Q2M226, Q658J2, Q76N05, Q96RZ3, Q9UJK1	Gene names	BAIAP3, KIAA0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

OTOF_MOUSE
θ value	0.0193708 (rank : 137)	NC score	0.197442 (rank : 129)
Query Neighborhood Hits	214	Target Neighborhood Hits	196	Shared Neighborhood Hits	97
SwissProt Accessions	Q9ESF1, Q9ESF2	Gene names	Otof, Fer1l2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

SYTL5_MOUSE
θ value	0.0193708 (rank : 138)	NC score	0.274178 (rank : 94)
Query Neighborhood Hits	214	Target Neighborhood Hits	154	Shared Neighborhood Hits	109
SwissProt Accessions	Q80T23, Q812E5	Gene names	Sytl5, Slp5
Domain Architecture
Description	Synaptotagmin-like protein 5.

APBB3_HUMAN
θ value	0.0252991 (rank : 139)	NC score	0.125325 (rank : 162)
Query Neighborhood Hits	214	Target Neighborhood Hits	36	Shared Neighborhood Hits	27
SwissProt Accessions	O95704, Q9NYX6, Q9NYX7, Q9NYX8	Gene names	APBB3, FE65L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 3 (Fe65-like protein 2) (Fe65L2).

APBB3_MOUSE
θ value	0.0330416 (rank : 140)	NC score	0.125023 (rank : 163)
Query Neighborhood Hits	214	Target Neighborhood Hits	32	Shared Neighborhood Hits	26
SwissProt Accessions	Q8R1C9	Gene names	Apbb3
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 3.

CPNE3_MOUSE
θ value	0.0330416 (rank : 141)	NC score	0.147038 (rank : 152)
Query Neighborhood Hits	214	Target Neighborhood Hits	90	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BT60, Q5CZX9, Q5DU22	Gene names	Cpne3, Kiaa0636
Domain Architecture
Description	Copine-3 (Copine III).

DYSF_MOUSE
θ value	0.0330416 (rank : 142)	NC score	0.202007 (rank : 126)
Query Neighborhood Hits	214	Target Neighborhood Hits	162	Shared Neighborhood Hits	117
SwissProt Accessions	Q9ESD7, Q9QXC0	Gene names	Dysf, Fer1l1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

SEM3E_HUMAN
θ value	0.0330416 (rank : 143)	NC score	0.014567 (rank : 226)
Query Neighborhood Hits	214	Target Neighborhood Hits	73	Shared Neighborhood Hits	5
SwissProt Accessions	O15041, Q75M94, Q75M97	Gene names	SEMA3E, KIAA0331
Domain Architecture	No domain graphic available
Description	Semaphorin-3E precursor.

SEM3E_MOUSE
θ value	0.0330416 (rank : 144)	NC score	0.014780 (rank : 225)
Query Neighborhood Hits	214	Target Neighborhood Hits	76	Shared Neighborhood Hits	5
SwissProt Accessions	P70275, O09078, O09079	Gene names	Sema3e, Semah, Semh
Domain Architecture
Description	Semaphorin-3E precursor (Semaphorin H) (Sema H).

TCRG1_HUMAN
θ value	0.0330416 (rank : 145)	NC score	0.084097 (rank : 192)
Query Neighborhood Hits	214	Target Neighborhood Hits	929	Shared Neighborhood Hits	40
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

STXB4_HUMAN
θ value	0.0431538 (rank : 146)	NC score	0.162760 (rank : 144)
Query Neighborhood Hits	214	Target Neighborhood Hits	616	Shared Neighborhood Hits	47
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

STXB4_MOUSE
θ value	0.0431538 (rank : 147)	NC score	0.163429 (rank : 143)
Query Neighborhood Hits	214	Target Neighborhood Hits	629	Shared Neighborhood Hits	47
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

SYT15_HUMAN
θ value	0.0563607 (rank : 148)	NC score	0.271746 (rank : 95)
Query Neighborhood Hits	214	Target Neighborhood Hits	112	Shared Neighborhood Hits	91
SwissProt Accessions	Q9BQS2, Q7Z439, Q7Z440	Gene names	SYT15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV) (Chr10Syt).

SYTL4_MOUSE
θ value	0.0563607 (rank : 149)	NC score	0.275411 (rank : 93)
Query Neighborhood Hits	214	Target Neighborhood Hits	137	Shared Neighborhood Hits	91
SwissProt Accessions	Q9R0Q1, Q8R321, Q9R0Q0	Gene names	Sytl4, Slp4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

DRP2_HUMAN
θ value	0.0736092 (rank : 150)	NC score	0.098518 (rank : 184)
Query Neighborhood Hits	214	Target Neighborhood Hits	186	Shared Neighborhood Hits	25
SwissProt Accessions	Q13474	Gene names	DRP2
Domain Architecture
Description	Dystrophin-related protein 2.

K0528_HUMAN
θ value	0.0961366 (rank : 151)	NC score	0.204893 (rank : 123)
Query Neighborhood Hits	214	Target Neighborhood Hits	96	Shared Neighborhood Hits	81
SwissProt Accessions	Q86YS7, O60280, Q7Z619, Q86SU3	Gene names	KIAA0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

K0528_MOUSE
θ value	0.0961366 (rank : 152)	NC score	0.204729 (rank : 124)
Query Neighborhood Hits	214	Target Neighborhood Hits	102	Shared Neighborhood Hits	82
SwissProt Accessions	Q7TPS5, Q3TQY6, Q6A052, Q80VA1, Q8C0U3, Q8CID5, Q9CS85	Gene names	Kiaa0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

PA24A_MOUSE
θ value	0.0961366 (rank : 153)	NC score	0.191331 (rank : 133)
Query Neighborhood Hits	214	Target Neighborhood Hits	100	Shared Neighborhood Hits	78
SwissProt Accessions	P47713	Gene names	Pla2g4a, Cpla2, Pla2g4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

RASA3_HUMAN
θ value	0.0961366 (rank : 154)	NC score	0.187758 (rank : 134)
Query Neighborhood Hits	214	Target Neighborhood Hits	166	Shared Neighborhood Hits	77
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

SYT15_MOUSE
θ value	0.125558 (rank : 155)	NC score	0.255889 (rank : 103)
Query Neighborhood Hits	214	Target Neighborhood Hits	100	Shared Neighborhood Hits	85
SwissProt Accessions	Q8C6N3, Q7TN81, Q7TN82, Q8C999	Gene names	Syt15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV).

PLCD1_MOUSE
θ value	0.163984 (rank : 156)	NC score	0.086366 (rank : 191)
Query Neighborhood Hits	214	Target Neighborhood Hits	106	Shared Neighborhood Hits	53
SwissProt Accessions	Q8R3B1	Gene names	Plcd1, Plcd
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

SETD2_HUMAN
θ value	0.163984 (rank : 157)	NC score	0.116731 (rank : 167)
Query Neighborhood Hits	214	Target Neighborhood Hits	412	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

UTRO_HUMAN
θ value	0.163984 (rank : 158)	NC score	0.043023 (rank : 220)
Query Neighborhood Hits	214	Target Neighborhood Hits	960	Shared Neighborhood Hits	41
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

DYSF_HUMAN
θ value	0.21417 (rank : 159)	NC score	0.211099 (rank : 120)
Query Neighborhood Hits	214	Target Neighborhood Hits	170	Shared Neighborhood Hits	120
SwissProt Accessions	O75923, O75696, Q9UEN7	Gene names	DYSF, FER1L1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

P3C2A_HUMAN
θ value	0.21417 (rank : 160)	NC score	0.138428 (rank : 155)
Query Neighborhood Hits	214	Target Neighborhood Hits	188	Shared Neighborhood Hits	69
SwissProt Accessions	O00443	Gene names	PIK3C2A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha).

RASA3_MOUSE
θ value	0.21417 (rank : 161)	NC score	0.166338 (rank : 141)
Query Neighborhood Hits	214	Target Neighborhood Hits	144	Shared Neighborhood Hits	70
SwissProt Accessions	Q60790	Gene names	Rasa3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) (GapIII).

TCRG1_MOUSE
θ value	0.21417 (rank : 162)	NC score	0.082093 (rank : 196)
Query Neighborhood Hits	214	Target Neighborhood Hits	947	Shared Neighborhood Hits	43
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

CPNE1_MOUSE
θ value	0.279714 (rank : 163)	NC score	0.135064 (rank : 158)
Query Neighborhood Hits	214	Target Neighborhood Hits	83	Shared Neighborhood Hits	72
SwissProt Accessions	Q8C166, Q925K4, Q925K5	Gene names	Cpne1
Domain Architecture
Description	Copine-1 (Copine I).

CPNE6_HUMAN
θ value	0.279714 (rank : 164)	NC score	0.111412 (rank : 173)
Query Neighborhood Hits	214	Target Neighborhood Hits	85	Shared Neighborhood Hits	71
SwissProt Accessions	O95741, Q53HA6, Q8WVG1	Gene names	CPNE6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

CPNE5_HUMAN
θ value	0.365318 (rank : 165)	NC score	0.147971 (rank : 151)
Query Neighborhood Hits	214	Target Neighborhood Hits	88	Shared Neighborhood Hits	75
SwissProt Accessions	Q9HCH3	Gene names	CPNE5, KIAA1599
Domain Architecture
Description	Copine-5 (Copine V).

CPNE5_MOUSE
θ value	0.365318 (rank : 166)	NC score	0.148042 (rank : 150)
Query Neighborhood Hits	214	Target Neighborhood Hits	86	Shared Neighborhood Hits	75
SwissProt Accessions	Q8JZW4	Gene names	Cpne5
Domain Architecture
Description	Copine-5 (Copine V).

RFIP2_HUMAN
θ value	0.365318 (rank : 167)	NC score	0.195269 (rank : 132)
Query Neighborhood Hits	214	Target Neighborhood Hits	97	Shared Neighborhood Hits	74
SwissProt Accessions	Q7L804, Q9Y2F0	Gene names	RAB11FIP2, KIAA0941
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 2 (Rab11-FIP2) (NRip11).

RIMS4_MOUSE
θ value	0.365318 (rank : 168)	NC score	0.170106 (rank : 139)
Query Neighborhood Hits	214	Target Neighborhood Hits	76	Shared Neighborhood Hits	65
SwissProt Accessions	P60191	Gene names	Rims4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

CPNE6_MOUSE
θ value	0.47712 (rank : 169)	NC score	0.110810 (rank : 174)
Query Neighborhood Hits	214	Target Neighborhood Hits	87	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Z140	Gene names	Cpne6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

RIMS4_HUMAN
θ value	0.47712 (rank : 170)	NC score	0.169326 (rank : 140)
Query Neighborhood Hits	214	Target Neighborhood Hits	76	Shared Neighborhood Hits	65
SwissProt Accessions	Q9H426, Q5JWT7	Gene names	RIMS4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

SYTL3_MOUSE
θ value	0.47712 (rank : 171)	NC score	0.243755 (rank : 108)
Query Neighborhood Hits	214	Target Neighborhood Hits	110	Shared Neighborhood Hits	78
SwissProt Accessions	Q99N48, Q8C506, Q99N47, Q99N49, Q99N54, Q99N79	Gene names	Sytl3, Slp3
Domain Architecture
Description	Synaptotagmin-like protein 3 (Exophilin-6).

CPNE8_HUMAN
θ value	0.62314 (rank : 172)	NC score	0.150834 (rank : 146)
Query Neighborhood Hits	214	Target Neighborhood Hits	86	Shared Neighborhood Hits	73
SwissProt Accessions	Q86YQ8, Q2TB41	Gene names	CPNE8
Domain Architecture
Description	Copine-8 (Copine VIII).

CPNE8_MOUSE
θ value	0.62314 (rank : 173)	NC score	0.148535 (rank : 149)
Query Neighborhood Hits	214	Target Neighborhood Hits	85	Shared Neighborhood Hits	72
SwissProt Accessions	Q9DC53, Q9CUZ8	Gene names	Cpne8
Domain Architecture
Description	Copine-8 (Copine VIII).

PA24A_HUMAN
θ value	0.62314 (rank : 174)	NC score	0.179538 (rank : 137)
Query Neighborhood Hits	214	Target Neighborhood Hits	88	Shared Neighborhood Hits	79
SwissProt Accessions	P47712	Gene names	PLA2G4A, CPLA2, PLA2G4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

RPGR1_MOUSE
θ value	0.62314 (rank : 175)	NC score	0.029219 (rank : 221)
Query Neighborhood Hits	214	Target Neighborhood Hits	713	Shared Neighborhood Hits	22
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

TOLIP_MOUSE
θ value	0.62314 (rank : 176)	NC score	0.110583 (rank : 176)
Query Neighborhood Hits	214	Target Neighborhood Hits	24	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QZ06, Q543N1, Q9D5P5	Gene names	Tollip
Domain Architecture
Description	Toll-interacting protein.

PA24F_HUMAN
θ value	0.813845 (rank : 177)	NC score	0.150075 (rank : 148)
Query Neighborhood Hits	214	Target Neighborhood Hits	78	Shared Neighborhood Hits	68
SwissProt Accessions	Q68DD2, Q6ZMC8	Gene names	PLA2G4F
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

SYT13_HUMAN
θ value	0.813845 (rank : 178)	NC score	0.223864 (rank : 117)
Query Neighborhood Hits	214	Target Neighborhood Hits	76	Shared Neighborhood Hits	65
SwissProt Accessions	Q7L8C5, Q9BQS3, Q9H041, Q9P2C0	Gene names	SYT13, KIAA1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

TOLIP_HUMAN
θ value	0.813845 (rank : 179)	NC score	0.102635 (rank : 182)
Query Neighborhood Hits	214	Target Neighborhood Hits	20	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H0E2, Q9H9E6, Q9UJ69	Gene names	TOLLIP
Domain Architecture
Description	Toll-interacting protein.

CASC5_HUMAN
θ value	1.06291 (rank : 180)	NC score	0.012277 (rank : 228)
Query Neighborhood Hits	214	Target Neighborhood Hits	376	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NG31, Q8NHE1, Q8WXA6, Q9HCK2, Q9NR92	Gene names	CASC5, KIAA1570
Domain Architecture	No domain graphic available
Description	Protein CASC5 (Cancer susceptibility candidate gene 5 protein) (ALL1- fused gene from chromosome 15q14) (AF15q14) (D40/AF15q14 protein).

CPNE3_HUMAN
θ value	1.06291 (rank : 181)	NC score	0.142010 (rank : 153)
Query Neighborhood Hits	214	Target Neighborhood Hits	90	Shared Neighborhood Hits	77
SwissProt Accessions	O75131, Q8IYA1	Gene names	CPNE3, CPN3, KIAA0636
Domain Architecture
Description	Copine-3 (Copine III).

M3K9_HUMAN
θ value	1.06291 (rank : 182)	NC score	0.005449 (rank : 237)
Query Neighborhood Hits	214	Target Neighborhood Hits	1123	Shared Neighborhood Hits	15
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

SYT13_MOUSE
θ value	1.06291 (rank : 183)	NC score	0.216670 (rank : 119)
Query Neighborhood Hits	214	Target Neighborhood Hits	69	Shared Neighborhood Hits	64
SwissProt Accessions	Q9EQT6, Q6ZPR2, Q8BRK6	Gene names	Syt13, Kiaa1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

ADA1D_MOUSE
θ value	1.38821 (rank : 184)	NC score	-0.005863 (rank : 245)
Query Neighborhood Hits	214	Target Neighborhood Hits	874	Shared Neighborhood Hits	2
SwissProt Accessions	P97714, Q61619	Gene names	Adra1d, Adra1a, Gpcr8
Domain Architecture
Description	Alpha-1D adrenergic receptor (Alpha 1D-adrenoceptor) (Alpha 1D- adrenoreceptor) (Alpha-1A adrenergic receptor).

P3C2A_MOUSE
θ value	1.38821 (rank : 185)	NC score	0.133541 (rank : 159)
Query Neighborhood Hits	214	Target Neighborhood Hits	181	Shared Neighborhood Hits	69
SwissProt Accessions	Q61194, Q61182	Gene names	Pik3c2a, Cpk
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).

SYT14_MOUSE
θ value	1.38821 (rank : 186)	NC score	0.209519 (rank : 122)
Query Neighborhood Hits	214	Target Neighborhood Hits	82	Shared Neighborhood Hits	58
SwissProt Accessions	Q7TN84	Gene names	Syt14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

ANPRA_HUMAN
θ value	1.81305 (rank : 187)	NC score	0.003661 (rank : 241)
Query Neighborhood Hits	214	Target Neighborhood Hits	612	Shared Neighborhood Hits	13
SwissProt Accessions	P16066, Q6P4Q3	Gene names	NPR1, ANPRA
Domain Architecture
Description	Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor).

CPNE1_HUMAN
θ value	1.81305 (rank : 188)	NC score	0.118435 (rank : 165)
Query Neighborhood Hits	214	Target Neighborhood Hits	70	Shared Neighborhood Hits	65
SwissProt Accessions	Q99829, Q6IBL3, Q9H243, Q9NTZ7	Gene names	CPNE1, CPN1
Domain Architecture
Description	Copine-1 (Copine I).

CPNE2_MOUSE
θ value	1.81305 (rank : 189)	NC score	0.138126 (rank : 156)
Query Neighborhood Hits	214	Target Neighborhood Hits	82	Shared Neighborhood Hits	70
SwissProt Accessions	P59108, Q8K1D7	Gene names	Cpne2
Domain Architecture
Description	Copine-2 (Copine II).

CPNE7_HUMAN
θ value	1.81305 (rank : 190)	NC score	0.116785 (rank : 166)
Query Neighborhood Hits	214	Target Neighborhood Hits	92	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UBL6	Gene names	CPNE7
Domain Architecture
Description	Copine-7 (Copine VII).

CHD8_HUMAN
θ value	2.36792 (rank : 191)	NC score	0.001800 (rank : 242)
Query Neighborhood Hits	214	Target Neighborhood Hits	235	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

RHG12_HUMAN
θ value	2.36792 (rank : 192)	NC score	0.088402 (rank : 190)
Query Neighborhood Hits	214	Target Neighborhood Hits	190	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RPGR1_HUMAN
θ value	2.36792 (rank : 193)	NC score	0.018955 (rank : 223)
Query Neighborhood Hits	214	Target Neighborhood Hits	578	Shared Neighborhood Hits	19
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

STAB1_MOUSE
θ value	2.36792 (rank : 194)	NC score	-0.002386 (rank : 244)
Query Neighborhood Hits	214	Target Neighborhood Hits	566	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

APBB1_HUMAN
θ value	3.0926 (rank : 195)	NC score	0.082676 (rank : 195)
Query Neighborhood Hits	214	Target Neighborhood Hits	62	Shared Neighborhood Hits	23
SwissProt Accessions	O00213, Q96A93	Gene names	APBB1, FE65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

APBB1_MOUSE
θ value	3.0926 (rank : 196)	NC score	0.083345 (rank : 194)
Query Neighborhood Hits	214	Target Neighborhood Hits	75	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QXJ1, O08642, Q3TPU0, Q8BNF4, Q8BSR9	Gene names	Apbb1, Fe65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

LSD1_HUMAN
θ value	3.0926 (rank : 197)	NC score	0.008210 (rank : 234)
Query Neighborhood Hits	214	Target Neighborhood Hits	455	Shared Neighborhood Hits	9
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

PRP16_HUMAN
θ value	3.0926 (rank : 198)	NC score	0.005719 (rank : 236)
Query Neighborhood Hits	214	Target Neighborhood Hits	135	Shared Neighborhood Hits	8
SwissProt Accessions	Q92620, O75212, Q96HN7	Gene names	DHX38, DDX38, KIAA0224, PRP16
Domain Architecture
Description	Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 (EC 3.6.1.-) (ATP-dependent RNA helicase DHX38) (DEAH box protein 38).

CPNE2_HUMAN
θ value	4.03905 (rank : 199)	NC score	0.135283 (rank : 157)
Query Neighborhood Hits	214	Target Neighborhood Hits	75	Shared Neighborhood Hits	69
SwissProt Accessions	Q96FN4, Q68D19, Q86XP9	Gene names	CPNE2
Domain Architecture
Description	Copine-2 (Copine II).

D2HDH_MOUSE
θ value	4.03905 (rank : 200)	NC score	0.012893 (rank : 227)
Query Neighborhood Hits	214	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CIM3, Q3TDF5, Q8BU06	Gene names	D2hgdh
Domain Architecture	No domain graphic available
Description	D-2-hydroxyglutarate dehydrogenase, mitochondrial precursor (EC 1.1.99.-).

FRS3_HUMAN
θ value	4.03905 (rank : 201)	NC score	0.016990 (rank : 224)
Query Neighborhood Hits	214	Target Neighborhood Hits	76	Shared Neighborhood Hits	6
SwissProt Accessions	O43559, Q5T3D5	Gene names	FRS3
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (Suc1-associated neurotrophic factor target 2) (SNT-2) (FGFR signaling adaptor SNT2).

RIMS3_HUMAN
θ value	4.03905 (rank : 202)	NC score	0.141517 (rank : 154)
Query Neighborhood Hits	214	Target Neighborhood Hits	66	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UJD0, Q92511	Gene names	RIMS3, KIAA0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

1433G_HUMAN
θ value	5.27518 (rank : 203)	NC score	0.003981 (rank : 239)
Query Neighborhood Hits	214	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	P61981, O70457, P35214, Q6FH52, Q9UDP2, Q9UN99	Gene names	YWHAG
Domain Architecture
Description	14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1).

1433G_MOUSE
θ value	5.27518 (rank : 204)	NC score	0.003981 (rank : 240)
Query Neighborhood Hits	214	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	P61982, O70457, P35214, Q3UFD6, Q4FK44, Q9UDP2, Q9UN99	Gene names	Ywhag
Domain Architecture
Description	14-3-3 protein gamma.

MYO15_HUMAN
θ value	5.27518 (rank : 205)	NC score	0.000026 (rank : 243)
Query Neighborhood Hits	214	Target Neighborhood Hits	671	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

RHG09_HUMAN
θ value	5.27518 (rank : 206)	NC score	0.027494 (rank : 222)
Query Neighborhood Hits	214	Target Neighborhood Hits	186	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

SYT14_HUMAN
θ value	5.27518 (rank : 207)	NC score	0.196677 (rank : 131)
Query Neighborhood Hits	214	Target Neighborhood Hits	81	Shared Neighborhood Hits	56
SwissProt Accessions	Q8NB59, Q5THX7, Q707N3, Q707N4, Q707N5, Q707N6, Q707N7	Gene names	SYT14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

CHMP7_HUMAN
θ value	6.88961 (rank : 208)	NC score	0.008482 (rank : 233)
Query Neighborhood Hits	214	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WUX9, Q8NDM1, Q9BT50	Gene names	CHMP7
Domain Architecture	No domain graphic available
Description	Protein CHMP7.

CHMP7_MOUSE
θ value	6.88961 (rank : 209)	NC score	0.008631 (rank : 232)
Query Neighborhood Hits	214	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R1T1, Q8CFW4	Gene names	Chmp7
Domain Architecture	No domain graphic available
Description	Protein CHMP7.

FA48A_HUMAN
θ value	6.88961 (rank : 210)	NC score	0.008946 (rank : 231)
Query Neighborhood Hits	214	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NEM7, Q71RF3, Q9Y6A6	Gene names	FAM48A
Domain Architecture	No domain graphic available
Description	Protein FAM48A (p38-interacting protein) (p38IP).

FA48A_MOUSE
θ value	6.88961 (rank : 211)	NC score	0.009501 (rank : 230)
Query Neighborhood Hits	214	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TT00, Q8BG53, Q9JLS9	Gene names	Fam48a, D3Ertd300e
Domain Architecture	No domain graphic available
Description	Protein FAM48A (p38-interacting protein) (p38IP).

MINT_HUMAN
θ value	8.99809 (rank : 212)	NC score	0.010195 (rank : 229)
Query Neighborhood Hits	214	Target Neighborhood Hits	1291	Shared Neighborhood Hits	29
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

RIPK5_MOUSE
θ value	8.99809 (rank : 213)	NC score	0.004805 (rank : 238)
Query Neighborhood Hits	214	Target Neighborhood Hits	874	Shared Neighborhood Hits	10
SwissProt Accessions	Q6XUX1, Q3ULK4, Q5EBN5, Q8C7D4, Q8C923, Q9CTP7	Gene names	Ripk5
Domain Architecture	No domain graphic available
Description	Receptor-interacting serine/threonine-protein kinase 5 (EC 2.7.11.1) (Dusty protein kinase) (Dusty PK).

SEM3D_HUMAN
θ value	8.99809 (rank : 214)	NC score	0.006866 (rank : 235)
Query Neighborhood Hits	214	Target Neighborhood Hits	104	Shared Neighborhood Hits	6
SwissProt Accessions	O95025, Q6UW77, Q8NCQ1	Gene names	SEMA3D
Domain Architecture
Description	Semaphorin-3D precursor.

ALS2_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.050030 (rank : 218)
Query Neighborhood Hits	214	Target Neighborhood Hits	121	Shared Neighborhood Hits	6
SwissProt Accessions	Q96Q42, Q8N1E0, Q96PC4, Q96Q41, Q9H973, Q9HCK9	Gene names	ALS2, KIAA1563
Domain Architecture
Description	Alsin (Amyotrophic lateral sclerosis protein 2).

CPNE4_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.093305 (rank : 186)
Query Neighborhood Hits	214	Target Neighborhood Hits	70	Shared Neighborhood Hits	64
SwissProt Accessions	Q96A23, Q8TEX1	Gene names	CPNE4
Domain Architecture
Description	Copine-4 (Copine IV) (Copine-8).

CPNE4_MOUSE
θ value	θ > 10 (rank : 217)	NC score	0.092657 (rank : 187)
Query Neighborhood Hits	214	Target Neighborhood Hits	67	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BLR2	Gene names	Cpne4
Domain Architecture	No domain graphic available
Description	Copine-4 (Copine IV).

CUL7_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.053380 (rank : 216)
Query Neighborhood Hits	214	Target Neighborhood Hits	41	Shared Neighborhood Hits	5
SwissProt Accessions	Q14999, Q5T654	Gene names	CUL7, KIAA0076
Domain Architecture
Description	Cullin-7 (CUL-7).

DGCR8_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.058769 (rank : 213)
Query Neighborhood Hits	214	Target Neighborhood Hits	72	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WYQ5, Q6DCB2, Q6MZE9, Q6Y2L0, Q96G39, Q96GP8, Q9H6L8, Q9H6T7, Q9NRW2	Gene names	DGCR8, C22orf12, DGCRK6
Domain Architecture
Description	DGCR8 protein (DiGeorge syndrome critical region 8).

DGCR8_MOUSE
θ value	θ > 10 (rank : 220)	NC score	0.056420 (rank : 215)
Query Neighborhood Hits	214	Target Neighborhood Hits	70	Shared Neighborhood Hits	12
SwissProt Accessions	Q9EQM6	Gene names	Dgcr8
Domain Architecture	No domain graphic available
Description	DGCR8 protein (DiGeorge syndrome critical region 8 homolog) (Gy1).

PA24C_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.073273 (rank : 207)
Query Neighborhood Hits	214	Target Neighborhood Hits	13	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UP65, O75457, Q9UG68	Gene names	PLA2G4C
Domain Architecture
Description	Cytosolic phospholipase A2 gamma precursor (EC 3.1.1.4) (cPLA2-gamma) (Phospholipase A2 group IVC).

RCBT1_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.057238 (rank : 214)
Query Neighborhood Hits	214	Target Neighborhood Hits	158	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NDN9, Q969U9	Gene names	RCBTB1, CLLD7, E4.5
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 1 (Regulator of chromosome condensation and BTB domain-containing protein 1) (Chronic lymphocytic leukemia deletion region gene 7 protein) (CLL deletion region gene 7 protein).

RCBT1_MOUSE
θ value	θ > 10 (rank : 223)	NC score	0.058801 (rank : 212)
Query Neighborhood Hits	214	Target Neighborhood Hits	157	Shared Neighborhood Hits	4
SwissProt Accessions	Q6NXM2, Q8BTZ6, Q8BZV0	Gene names	Rcbtb1
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 1 (Regulator of chromosome condensation and BTB domain-containing protein 1).

RCBT2_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.063560 (rank : 210)
Query Neighborhood Hits	214	Target Neighborhood Hits	158	Shared Neighborhood Hits	6
SwissProt Accessions	O95199	Gene names	RCBTB2, CHC1L, RLG
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 2 (Regulator of chromosome condensation and BTB domain-containing protein 2) (Chromosome condensation 1-like) (CHC1-L) (RCC1-like G exchanging factor).

RCBT2_MOUSE
θ value	θ > 10 (rank : 225)	NC score	0.064412 (rank : 209)
Query Neighborhood Hits	214	Target Neighborhood Hits	156	Shared Neighborhood Hits	6
SwissProt Accessions	Q99LJ7, Q3TUA3, Q8BMG2	Gene names	Rcbtb2, Chc1l
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 2 (Regulator of chromosome condensation and BTB domain-containing protein 2) (Chromosome condensation 1-like).

RCC1_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.077340 (rank : 203)
Query Neighborhood Hits	214	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	P18754	Gene names	RCC1, CHC1
Domain Architecture
Description	Regulator of chromosome condensation (Chromosome condensation protein 1) (Cell cycle regulatory protein).

RCC1_MOUSE
θ value	θ > 10 (rank : 227)	NC score	0.075699 (rank : 204)
Query Neighborhood Hits	214	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VE37, Q3UDB6	Gene names	Rcc1, Chc1
Domain Architecture	No domain graphic available
Description	Regulator of chromosome condensation (Chromosome condensation protein 1).

RCC2_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.080549 (rank : 200)
Query Neighborhood Hits	214	Target Neighborhood Hits	36	Shared Neighborhood Hits	6
SwissProt Accessions	Q9P258, Q8IVL9, Q9BSN6, Q9NPV8	Gene names	RCC2, KIAA1470, TD60
Domain Architecture	No domain graphic available
Description	Protein RCC2 (Telophase disk protein of 60 kDa) (RCC1-like protein TD- 60).

RCC2_MOUSE
θ value	θ > 10 (rank : 229)	NC score	0.080010 (rank : 201)
Query Neighborhood Hits	214	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BK67, Q6ZPQ0	Gene names	Rcc2, Kiaa1470
Domain Architecture	No domain graphic available
Description	Protein RCC2.

RFIP1_HUMAN
θ value	θ > 10 (rank : 230)	NC score	0.071251 (rank : 208)
Query Neighborhood Hits	214	Target Neighborhood Hits	236	Shared Neighborhood Hits	43
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

RFIP1_MOUSE
θ value	θ > 10 (rank : 231)	NC score	0.081833 (rank : 197)
Query Neighborhood Hits	214	Target Neighborhood Hits	152	Shared Neighborhood Hits	42
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

RGS3_HUMAN
θ value	θ > 10 (rank : 232)	NC score	0.089876 (rank : 189)
Query Neighborhood Hits	214	Target Neighborhood Hits	1375	Shared Neighborhood Hits	82
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RIMS3_MOUSE
θ value	θ > 10 (rank : 233)	NC score	0.132052 (rank : 160)
Query Neighborhood Hits	214	Target Neighborhood Hits	67	Shared Neighborhood Hits	60
SwissProt Accessions	Q80U57	Gene names	Rims3, Kiaa0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

RPGR_HUMAN
θ value	θ > 10 (rank : 234)	NC score	0.081620 (rank : 198)
Query Neighborhood Hits	214	Target Neighborhood Hits	279	Shared Neighborhood Hits	9
SwissProt Accessions	Q92834, O00702, O00737, Q8N5T6, Q93039, Q9HD29, Q9UMR1	Gene names	RPGR, RP3, XLRP3
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator.

RPGR_MOUSE
θ value	θ > 10 (rank : 235)	NC score	0.077377 (rank : 202)
Query Neighborhood Hits	214	Target Neighborhood Hits	281	Shared Neighborhood Hits	8
SwissProt Accessions	Q9R0X5, O88408, Q9CU92	Gene names	Rpgr
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator (mRpgr).

SRGEF_HUMAN
θ value	θ > 10 (rank : 236)	NC score	0.083774 (rank : 193)
Query Neighborhood Hits	214	Target Neighborhood Hits	33	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UGK8, Q9UGK9	Gene names	SERGEF, DELGEF, GNEFR
Domain Architecture	No domain graphic available
Description	Secretion-regulating guanine nucleotide exchange factor (Guanine nucleotide exchange factor-related protein) (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF).

SRGEF_MOUSE
θ value	θ > 10 (rank : 237)	NC score	0.081264 (rank : 199)
Query Neighborhood Hits	214	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	Q80YD6, Q9QXB7	Gene names	Sergef, Delgef, Gnefr
Domain Architecture	No domain graphic available
Description	Secretion-regulating guanine nucleotide exchange factor (Guanine nucleotide exchange factor-related protein) (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF).

SYT12_HUMAN
θ value	θ > 10 (rank : 238)	NC score	0.240208 (rank : 110)
Query Neighborhood Hits	214	Target Neighborhood Hits	100	Shared Neighborhood Hits	87
SwissProt Accessions	Q8IV01	Gene names	SYT12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

SYT12_MOUSE
θ value	θ > 10 (rank : 239)	NC score	0.241945 (rank : 109)
Query Neighborhood Hits	214	Target Neighborhood Hits	102	Shared Neighborhood Hits	90
SwissProt Accessions	Q920N7	Gene names	Syt12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

SYT8_MOUSE
θ value	θ > 10 (rank : 240)	NC score	0.244126 (rank : 107)
Query Neighborhood Hits	214	Target Neighborhood Hits	94	Shared Neighborhood Hits	85
SwissProt Accessions	Q9R0N6, Q64366, Q8C6E7	Gene names	Syt8
Domain Architecture
Description	Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII).

TAC2N_HUMAN
θ value	θ > 10 (rank : 241)	NC score	0.105371 (rank : 179)
Query Neighborhood Hits	214	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	Q8N9U0	Gene names	MTAC2D1, C14orf47
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

TAC2N_MOUSE
θ value	θ > 10 (rank : 242)	NC score	0.102514 (rank : 183)
Query Neighborhood Hits	214	Target Neighborhood Hits	43	Shared Neighborhood Hits	33
SwissProt Accessions	Q91XT6, Q9D4A0	Gene names	Mtac2d1
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

WBP4_MOUSE
θ value	θ > 10 (rank : 243)	NC score	0.092204 (rank : 188)
Query Neighborhood Hits	214	Target Neighborhood Hits	100	Shared Neighborhood Hits	30
SwissProt Accessions	Q61048, Q8K1Z9, Q9CS45	Gene names	Wbp4, Fbp21, Fnbp21
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21).

WBS16_HUMAN
θ value	θ > 10 (rank : 244)	NC score	0.073939 (rank : 206)
Query Neighborhood Hits	214	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q96I51, Q548B1, Q9H0G7	Gene names	WBSCR16
Domain Architecture	No domain graphic available
Description	Williams-Beuren syndrome chromosome region 16 protein (RCC1-like G exchanging factor-like protein).

WBS16_MOUSE
θ value	θ > 10 (rank : 245)	NC score	0.075627 (rank : 205)
Query Neighborhood Hits	214	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CYF5	Gene names	Wbscr16
Domain Architecture	No domain graphic available
Description	Williams-Beuren syndrome chromosome region 16 protein homolog.

Hits sorted by NC score

NEDD4_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	214	Target Neighborhood Hits	214	Shared Neighborhood Hits	214
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

NEDD4_MOUSE
NC score	0.996492 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	214	Target Neighborhood Hits	212	Shared Neighborhood Hits	193
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

NED4L_HUMAN
NC score	0.991260 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	214	Target Neighborhood Hits	238	Shared Neighborhood Hits	189
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NED4L_MOUSE
NC score	0.990827 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	214	Target Neighborhood Hits	231	Shared Neighborhood Hits	188
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

SMUF2_HUMAN
NC score	0.946445 (rank : 5)	θ value	2.689e-137 (rank : 11)
Query Neighborhood Hits	214	Target Neighborhood Hits	142	Shared Neighborhood Hits	135
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

SMUF1_MOUSE
NC score	0.941622 (rank : 6)	θ value	7.33985e-127 (rank : 12)
Query Neighborhood Hits	214	Target Neighborhood Hits	142	Shared Neighborhood Hits	123
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

SMUF1_HUMAN
NC score	0.939658 (rank : 7)	θ value	6.21357e-126 (rank : 13)
Query Neighborhood Hits	214	Target Neighborhood Hits	135	Shared Neighborhood Hits	120
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

ITCH_MOUSE
NC score	0.917777 (rank : 8)	θ value	5.22361e-149 (rank : 6)
Query Neighborhood Hits	214	Target Neighborhood Hits	127	Shared Neighborhood Hits	87
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

WWP1_MOUSE
NC score	0.914846 (rank : 9)	θ value	3.87392e-144 (rank : 9)
Query Neighborhood Hits	214	Target Neighborhood Hits	138	Shared Neighborhood Hits	86
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

WWP2_MOUSE
NC score	0.914036 (rank : 10)	θ value	2.42647e-146 (rank : 8)
Query Neighborhood Hits	214	Target Neighborhood Hits	118	Shared Neighborhood Hits	80
SwissProt Accessions	Q9DBH0, Q8BTG4, Q923F6	Gene names	Wwp2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2).

ITCH_HUMAN
NC score	0.911498 (rank : 11)	θ value	1.79534e-149 (rank : 5)
Query Neighborhood Hits	214	Target Neighborhood Hits	162	Shared Neighborhood Hits	93
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

WWP2_HUMAN
NC score	0.910956 (rank : 12)	θ value	2.19465e-147 (rank : 7)
Query Neighborhood Hits	214	Target Neighborhood Hits	177	Shared Neighborhood Hits	76
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

WWP1_HUMAN
NC score	0.906844 (rank : 13)	θ value	3.27947e-143 (rank : 10)
Query Neighborhood Hits	214	Target Neighborhood Hits	262	Shared Neighborhood Hits	85
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

K0317_HUMAN
NC score	0.841558 (rank : 14)	θ value	1.61343e-57 (rank : 16)
Query Neighborhood Hits	214	Target Neighborhood Hits	46	Shared Neighborhood Hits	35
SwissProt Accessions	O15033, Q7LDY1, Q8IYY9	Gene names	KIAA0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

K0317_MOUSE
NC score	0.841314 (rank : 15)	θ value	2.10721e-57 (rank : 17)
Query Neighborhood Hits	214	Target Neighborhood Hits	43	Shared Neighborhood Hits	35
SwissProt Accessions	Q8CHG5, Q6P9Q1, Q80YC4, Q8C5W5	Gene names	Kiaa0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

HECD2_MOUSE
NC score	0.835005 (rank : 16)	θ value	9.48078e-50 (rank : 20)
Query Neighborhood Hits	214	Target Neighborhood Hits	38	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CDU6, Q8CBQ9	Gene names	Hectd2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

HECD2_HUMAN
NC score	0.832610 (rank : 17)	θ value	7.25919e-50 (rank : 19)
Query Neighborhood Hits	214	Target Neighborhood Hits	41	Shared Neighborhood Hits	34
SwissProt Accessions	Q5U5R9, Q5VZ97, Q5VZ99, Q8TCP5	Gene names	HECTD2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

UBE3A_HUMAN
NC score	0.831037 (rank : 18)	θ value	1.32293e-51 (rank : 18)
Query Neighborhood Hits	214	Target Neighborhood Hits	49	Shared Neighborhood Hits	33
SwissProt Accessions	Q05086, P78355, Q93066, Q9UEP4, Q9UEP5, Q9UEP6, Q9UEP7, Q9UEP8, Q9UEP9	Gene names	UBE3A, E6AP
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Oncogenic protein-associated protein E6-AP) (Human papillomavirus E6-associated protein) (NY-REN-54 antigen).

UBE3A_MOUSE
NC score	0.825932 (rank : 19)	θ value	3.04986e-48 (rank : 21)
Query Neighborhood Hits	214	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	O08759, P97482	Gene names	Ube3a
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (Oncogenic protein- associated protein E6-AP).

HUWE1_MOUSE
NC score	0.824997 (rank : 20)	θ value	4.06505e-93 (rank : 15)
Query Neighborhood Hits	214	Target Neighborhood Hits	406	Shared Neighborhood Hits	40
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

HUWE1_HUMAN
NC score	0.823868 (rank : 21)	θ value	4.06505e-93 (rank : 14)
Query Neighborhood Hits	214	Target Neighborhood Hits	443	Shared Neighborhood Hits	38
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

UBE3C_HUMAN
NC score	0.819748 (rank : 22)	θ value	1.67352e-46 (rank : 22)
Query Neighborhood Hits	214	Target Neighborhood Hits	51	Shared Neighborhood Hits	35
SwissProt Accessions	Q15386, Q8TC15, Q96CR4, Q9UDU3	Gene names	UBE3C, KIAA0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

UBE3C_MOUSE
NC score	0.818338 (rank : 23)	θ value	3.72821e-46 (rank : 23)
Query Neighborhood Hits	214	Target Neighborhood Hits	48	Shared Neighborhood Hits	35
SwissProt Accessions	Q80U95, Q8BQZ6, Q8C7W6, Q8CDJ1, Q8VDL5	Gene names	Ube3c, Kiaa0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

TRIPC_HUMAN
NC score	0.740141 (rank : 24)	θ value	1.37858e-24 (rank : 28)
Query Neighborhood Hits	214	Target Neighborhood Hits	319	Shared Neighborhood Hits	39
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

HERC5_HUMAN
NC score	0.697252 (rank : 25)	θ value	3.05695e-40 (rank : 25)
Query Neighborhood Hits	214	Target Neighborhood Hits	66	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UII4	Gene names	HERC5, CEB1, CEBP1
Domain Architecture
Description	HECT domain and RCC1-like domain-containing protein 5 (Cyclin-E- binding protein 1).

HERC3_HUMAN
NC score	0.690178 (rank : 26)	θ value	1.19932e-44 (rank : 24)
Query Neighborhood Hits	214	Target Neighborhood Hits	62	Shared Neighborhood Hits	33
SwissProt Accessions	Q15034	Gene names	HERC3, KIAA0032
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain protein 3.

HECD3_MOUSE
NC score	0.658858 (rank : 27)	θ value	1.058e-16 (rank : 33)
Query Neighborhood Hits	214	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	Q3U487, Q3TN76, Q641P3, Q8BQ74, Q8R1L6	Gene names	Hectd3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

HECD3_HUMAN
NC score	0.654136 (rank : 28)	θ value	2.35696e-16 (rank : 34)
Query Neighborhood Hits	214	Target Neighborhood Hits	49	Shared Neighborhood Hits	33
SwissProt Accessions	Q5T447, Q5T448, Q9H783	Gene names	HECTD3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

EDD1_MOUSE
NC score	0.635845 (rank : 29)	θ value	7.82807e-20 (rank : 30)
Query Neighborhood Hits	214	Target Neighborhood Hits	167	Shared Neighborhood Hits	34
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

EDD1_HUMAN
NC score	0.634484 (rank : 30)	θ value	7.82807e-20 (rank : 29)
Query Neighborhood Hits	214	Target Neighborhood Hits	170	Shared Neighborhood Hits	33
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

HERC2_MOUSE
NC score	0.582219 (rank : 31)	θ value	1.33217e-27 (rank : 26)
Query Neighborhood Hits	214	Target Neighborhood Hits	167	Shared Neighborhood Hits	37
SwissProt Accessions	Q4U2R1, O88473, Q3TRJ8, Q3TS47, Q3TST2, Q3UFQ6, Q3URH7, Q5DU32, Q7TPR5, Q80VV7, Q9QYT1, Q9Z168, Q9Z171	Gene names	Herc2, jdf2, Kiaa0393, rjs
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

HERC2_HUMAN
NC score	0.578393 (rank : 32)	θ value	5.06226e-27 (rank : 27)
Query Neighborhood Hits	214	Target Neighborhood Hits	163	Shared Neighborhood Hits	37
SwissProt Accessions	O95714, Q86SV7, Q86SV8, Q86SV9, Q86YY3, Q86YY4, Q86YY5, Q86YY6, Q86YY7, Q86YY8, Q86YY9, Q86YZ0, Q86YZ1	Gene names	HERC2
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

HECD1_HUMAN
NC score	0.523249 (rank : 33)	θ value	1.24977e-17 (rank : 31)
Query Neighborhood Hits	214	Target Neighborhood Hits	371	Shared Neighborhood Hits	35
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

YAP1_MOUSE
NC score	0.520319 (rank : 34)	θ value	8.10077e-17 (rank : 32)
Query Neighborhood Hits	214	Target Neighborhood Hits	96	Shared Neighborhood Hits	51
SwissProt Accessions	P46938, Q52KJ5	Gene names	Yap1, Yap, Yap65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

SAV1_HUMAN
NC score	0.473618 (rank : 35)	θ value	1.53129e-07 (rank : 70)
Query Neighborhood Hits	214	Target Neighborhood Hits	51	Shared Neighborhood Hits	43
SwissProt Accessions	Q9H4B6, Q6IA58, Q9H949, Q9HAK9	Gene names	SAV1, WW45
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (hWW45).

SAV1_MOUSE
NC score	0.473214 (rank : 36)	θ value	6.87365e-08 (rank : 67)
Query Neighborhood Hits	214	Target Neighborhood Hits	48	Shared Neighborhood Hits	41
SwissProt Accessions	Q8VEB2, Q9D9N9, Q9ER46	Gene names	Sav1, Ww45, Wwp3
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (mWW45).

WWC1_MOUSE
NC score	0.440653 (rank : 37)	θ value	1.33837e-11 (rank : 37)
Query Neighborhood Hits	214	Target Neighborhood Hits	290	Shared Neighborhood Hits	62
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

WWC1_HUMAN
NC score	0.427514 (rank : 38)	θ value	1.33837e-11 (rank : 36)
Query Neighborhood Hits	214	Target Neighborhood Hits	290	Shared Neighborhood Hits	59
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

PINL_HUMAN
NC score	0.392242 (rank : 39)	θ value	0.00665767 (rank : 124)
Query Neighborhood Hits	214	Target Neighborhood Hits	47	Shared Neighborhood Hits	43
SwissProt Accessions	O15428	Gene names	PIN1L
Domain Architecture
Description	PIN1-like protein.

DOC2A_MOUSE
NC score	0.374000 (rank : 40)	θ value	1.06045e-08 (rank : 56)
Query Neighborhood Hits	214	Target Neighborhood Hits	140	Shared Neighborhood Hits	121
SwissProt Accessions	Q7TNF0	Gene names	Doc2a
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha).

DOC2B_HUMAN
NC score	0.368151 (rank : 41)	θ value	6.87365e-08 (rank : 65)
Query Neighborhood Hits	214	Target Neighborhood Hits	150	Shared Neighborhood Hits	121
SwissProt Accessions	Q14184	Gene names	DOC2B
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

DOC2A_HUMAN
NC score	0.367919 (rank : 42)	θ value	4.45536e-07 (rank : 74)
Query Neighborhood Hits	214	Target Neighborhood Hits	144	Shared Neighborhood Hits	119
SwissProt Accessions	Q14183, Q6P4G4, Q7Z5G0, Q8IVX0	Gene names	DOC2A
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha) (Doc2).

DOC2B_MOUSE
NC score	0.366578 (rank : 43)	θ value	8.97725e-08 (rank : 68)
Query Neighborhood Hits	214	Target Neighborhood Hits	169	Shared Neighborhood Hits	122
SwissProt Accessions	P70169, Q6NXK3	Gene names	Doc2b
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

FA62A_MOUSE
NC score	0.360576 (rank : 44)	θ value	4.92598e-06 (rank : 88)
Query Neighborhood Hits	214	Target Neighborhood Hits	155	Shared Neighborhood Hits	119
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

SYT7_HUMAN
NC score	0.360183 (rank : 45)	θ value	9.59137e-10 (rank : 47)
Query Neighborhood Hits	214	Target Neighborhood Hits	137	Shared Neighborhood Hits	118
SwissProt Accessions	O43581	Gene names	SYT7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

WWOX_HUMAN
NC score	0.359781 (rank : 46)	θ value	2.52405e-10 (rank : 42)
Query Neighborhood Hits	214	Target Neighborhood Hits	115	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NZC7, Q5MYT5, Q96KM3, Q96RF2, Q9BTT8, Q9NPC9, Q9NRF4, Q9NRF5, Q9NRF6, Q9NRK1, Q9NZC5	Gene names	WWOX, FOR, WOX1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-) (Fragile site FRA16D oxidoreductase).

SYT7_MOUSE
NC score	0.359168 (rank : 47)	θ value	2.52405e-10 (rank : 41)
Query Neighborhood Hits	214	Target Neighborhood Hits	137	Shared Neighborhood Hits	118
SwissProt Accessions	Q9R0N7	Gene names	Syt7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

WWOX_MOUSE
NC score	0.356658 (rank : 48)	θ value	2.52405e-10 (rank : 43)
Query Neighborhood Hits	214	Target Neighborhood Hits	118	Shared Neighborhood Hits	48
SwissProt Accessions	Q91WL8, Q8C8J6, Q920Y2, Q9D2B3, Q9D339, Q9JLF5	Gene names	Wwox, Wox1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-).

WWTR1_MOUSE
NC score	0.355080 (rank : 49)	θ value	5.44631e-05 (rank : 97)
Query Neighborhood Hits	214	Target Neighborhood Hits	54	Shared Neighborhood Hits	39
SwissProt Accessions	Q9EPK5, Q99KI4	Gene names	Wwtr1, Taz
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

WWTR1_HUMAN
NC score	0.351637 (rank : 50)	θ value	5.44631e-05 (rank : 96)
Query Neighborhood Hits	214	Target Neighborhood Hits	76	Shared Neighborhood Hits	41
SwissProt Accessions	Q9GZV5, Q8N3P2, Q9Y3W6	Gene names	WWTR1, TAZ
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

SYT10_HUMAN
NC score	0.350901 (rank : 51)	θ value	1.38499e-08 (rank : 58)
Query Neighborhood Hits	214	Target Neighborhood Hits	134	Shared Neighborhood Hits	119
SwissProt Accessions	Q6XYQ8	Gene names	SYT10
Domain Architecture	No domain graphic available
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

YAP1_HUMAN
NC score	0.350602 (rank : 52)	θ value	0.00020696 (rank : 101)
Query Neighborhood Hits	214	Target Neighborhood Hits	173	Shared Neighborhood Hits	51
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

SYT10_MOUSE
NC score	0.349848 (rank : 53)	θ value	2.13673e-09 (rank : 51)
Query Neighborhood Hits	214	Target Neighborhood Hits	133	Shared Neighborhood Hits	119
SwissProt Accessions	Q9R0N4	Gene names	Syt10
Domain Architecture
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

SYT5_HUMAN
NC score	0.349670 (rank : 54)	θ value	1.53129e-07 (rank : 71)
Query Neighborhood Hits	214	Target Neighborhood Hits	138	Shared Neighborhood Hits	120
SwissProt Accessions	O00445, Q86X72	Gene names	SYT5
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV).

RP3A_HUMAN
NC score	0.348737 (rank : 55)	θ value	1.99992e-07 (rank : 72)
Query Neighborhood Hits	214	Target Neighborhood Hits	305	Shared Neighborhood Hits	122
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SYT1_HUMAN
NC score	0.347023 (rank : 56)	θ value	2.21117e-06 (rank : 85)
Query Neighborhood Hits	214	Target Neighborhood Hits	150	Shared Neighborhood Hits	121
SwissProt Accessions	P21579	Gene names	SYT1, SYT
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT1_MOUSE
NC score	0.347018 (rank : 57)	θ value	2.21117e-06 (rank : 86)
Query Neighborhood Hits	214	Target Neighborhood Hits	150	Shared Neighborhood Hits	121
SwissProt Accessions	P46096	Gene names	Syt1
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT9_MOUSE
NC score	0.346262 (rank : 58)	θ value	7.34386e-10 (rank : 46)
Query Neighborhood Hits	214	Target Neighborhood Hits	148	Shared Neighborhood Hits	122
SwissProt Accessions	Q9R0N9, Q8C280	Gene names	Syt9, Syt5
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX) (Synaptotagmin V).

SYT3_MOUSE
NC score	0.345231 (rank : 59)	θ value	1.38499e-08 (rank : 59)
Query Neighborhood Hits	214	Target Neighborhood Hits	147	Shared Neighborhood Hits	117
SwissProt Accessions	O35681, P97791, Q80WV1	Gene names	Syt3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

SYT9_HUMAN
NC score	0.344763 (rank : 60)	θ value	8.11959e-09 (rank : 55)
Query Neighborhood Hits	214	Target Neighborhood Hits	144	Shared Neighborhood Hits	121
SwissProt Accessions	Q86SS6	Gene names	SYT9
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX).

SYT3_HUMAN
NC score	0.344607 (rank : 61)	θ value	2.36244e-08 (rank : 63)
Query Neighborhood Hits	214	Target Neighborhood Hits	145	Shared Neighborhood Hits	117
SwissProt Accessions	Q9BQG1, Q8N5Z1, Q8N640	Gene names	SYT3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

SYT6_MOUSE
NC score	0.344459 (rank : 62)	θ value	1.80886e-08 (rank : 61)
Query Neighborhood Hits	214	Target Neighborhood Hits	132	Shared Neighborhood Hits	118
SwissProt Accessions	Q9R0N8	Gene names	Syt6
Domain Architecture
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

DOC2G_MOUSE
NC score	0.344453 (rank : 63)	θ value	6.87365e-08 (rank : 66)
Query Neighborhood Hits	214	Target Neighborhood Hits	125	Shared Neighborhood Hits	106
SwissProt Accessions	Q9ESN1, Q6P8R8	Gene names	Doc2g
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein gamma (Doc2-gamma).

FA62A_HUMAN
NC score	0.343386 (rank : 64)	θ value	1.09739e-05 (rank : 92)
Query Neighborhood Hits	214	Target Neighborhood Hits	168	Shared Neighborhood Hits	117
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

SYT2_MOUSE
NC score	0.343343 (rank : 65)	θ value	1.29631e-06 (rank : 79)
Query Neighborhood Hits	214	Target Neighborhood Hits	143	Shared Neighborhood Hits	121
SwissProt Accessions	P46097, Q8R0E1	Gene names	Syt2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

RP3A_MOUSE
NC score	0.343199 (rank : 66)	θ value	2.61198e-07 (rank : 73)
Query Neighborhood Hits	214	Target Neighborhood Hits	510	Shared Neighborhood Hits	121
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SYT2_HUMAN
NC score	0.342982 (rank : 67)	θ value	1.29631e-06 (rank : 78)
Query Neighborhood Hits	214	Target Neighborhood Hits	142	Shared Neighborhood Hits	121
SwissProt Accessions	Q8N9I0, Q496K5, Q8NBE5	Gene names	SYT2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT6_HUMAN
NC score	0.342970 (rank : 68)	θ value	4.0297e-08 (rank : 64)
Query Neighborhood Hits	214	Target Neighborhood Hits	138	Shared Neighborhood Hits	117
SwissProt Accessions	Q5T7P8	Gene names	SYT6
Domain Architecture	No domain graphic available
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

SYT5_MOUSE
NC score	0.342964 (rank : 69)	θ value	4.92598e-06 (rank : 89)
Query Neighborhood Hits	214	Target Neighborhood Hits	140	Shared Neighborhood Hits	118
SwissProt Accessions	Q9R0N5	Gene names	Syt5, Syt9
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV) (Synaptotagmin IX).

RASL2_HUMAN
NC score	0.342220 (rank : 70)	θ value	4.76016e-09 (rank : 54)
Query Neighborhood Hits	214	Target Neighborhood Hits	161	Shared Neighborhood Hits	112
SwissProt Accessions	O43374, O60286, Q86UW3, Q96QU0	Gene names	RASA4, CAPRI, GAPL, KIAA0538
Domain Architecture
Description	Ras GTPase-activating protein 4 (RasGAP-activating-like protein 2) (Calcium-promoted Ras inactivator).

PIN1_MOUSE
NC score	0.342198 (rank : 71)	θ value	0.00228821 (rank : 112)
Query Neighborhood Hits	214	Target Neighborhood Hits	60	Shared Neighborhood Hits	46
SwissProt Accessions	Q9QUR7, Q543B3	Gene names	Pin1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

PIN1_HUMAN
NC score	0.340040 (rank : 72)	θ value	0.00228821 (rank : 111)
Query Neighborhood Hits	214	Target Neighborhood Hits	59	Shared Neighborhood Hits	44
SwissProt Accessions	Q13526	Gene names	PIN1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

BAG3_HUMAN
NC score	0.336130 (rank : 73)	θ value	2.88788e-06 (rank : 87)
Query Neighborhood Hits	214	Target Neighborhood Hits	314	Shared Neighborhood Hits	41
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

RASL1_HUMAN
NC score	0.320969 (rank : 74)	θ value	1.06045e-08 (rank : 57)
Query Neighborhood Hits	214	Target Neighborhood Hits	142	Shared Neighborhood Hits	101
SwissProt Accessions	O95294, Q52M03, Q96CC7	Gene names	RASAL1, RASAL
Domain Architecture
Description	RasGAP-activating-like protein 1.

SYT4_MOUSE
NC score	0.313041 (rank : 75)	θ value	7.1131e-05 (rank : 98)
Query Neighborhood Hits	214	Target Neighborhood Hits	123	Shared Neighborhood Hits	104
SwissProt Accessions	P40749, Q3UFC1, Q8BGH3, Q8BRL6	Gene names	Syt4, Syt3
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

SYT11_MOUSE
NC score	0.310505 (rank : 76)	θ value	0.000602161 (rank : 106)
Query Neighborhood Hits	214	Target Neighborhood Hits	116	Shared Neighborhood Hits	101
SwissProt Accessions	Q9R0N3	Gene names	Syt11
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

SYT11_HUMAN
NC score	0.310444 (rank : 77)	θ value	0.000602161 (rank : 105)
Query Neighborhood Hits	214	Target Neighborhood Hits	113	Shared Neighborhood Hits	99
SwissProt Accessions	Q9BT88, Q14998, Q68CT5, Q8IXU3, Q96SU2	Gene names	SYT11, KIAA0080
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

SYT4_HUMAN
NC score	0.309974 (rank : 78)	θ value	0.000121331 (rank : 100)
Query Neighborhood Hits	214	Target Neighborhood Hits	121	Shared Neighborhood Hits	106
SwissProt Accessions	Q9H2B2, Q9P2K4	Gene names	SYT4, KIAA1342
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

RASL1_MOUSE
NC score	0.309596 (rank : 79)	θ value	1.80886e-08 (rank : 60)
Query Neighborhood Hits	214	Target Neighborhood Hits	148	Shared Neighborhood Hits	100
SwissProt Accessions	Q9Z268	Gene names	Rasal1, Rasal
Domain Architecture
Description	RasGAP-activating-like protein 1.

MAGI2_MOUSE
NC score	0.300823 (rank : 80)	θ value	6.64225e-11 (rank : 39)
Query Neighborhood Hits	214	Target Neighborhood Hits	370	Shared Neighborhood Hits	50
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

UN13B_MOUSE
NC score	0.300600 (rank : 81)	θ value	2.79066e-09 (rank : 53)
Query Neighborhood Hits	214	Target Neighborhood Hits	210	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

UN13B_HUMAN
NC score	0.298702 (rank : 82)	θ value	2.13673e-09 (rank : 52)
Query Neighborhood Hits	214	Target Neighborhood Hits	217	Shared Neighborhood Hits	106
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

UN13A_HUMAN
NC score	0.295135 (rank : 83)	θ value	1.80886e-08 (rank : 62)
Query Neighborhood Hits	214	Target Neighborhood Hits	285	Shared Neighborhood Hits	105
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

UN13D_HUMAN
NC score	0.294176 (rank : 84)	θ value	0.000270298 (rank : 102)
Query Neighborhood Hits	214	Target Neighborhood Hits	117	Shared Neighborhood Hits	94
SwissProt Accessions	Q70J99, Q9H7K5	Gene names	UNC13D
Domain Architecture	No domain graphic available
Description	Unc-13 homolog D (Munc13-4).

BAG3_MOUSE
NC score	0.290936 (rank : 85)	θ value	1.69304e-06 (rank : 80)
Query Neighborhood Hits	214	Target Neighborhood Hits	513	Shared Neighborhood Hits	43
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

SYTL2_HUMAN
NC score	0.289886 (rank : 86)	θ value	1.87187e-05 (rank : 93)
Query Neighborhood Hits	214	Target Neighborhood Hits	248	Shared Neighborhood Hits	95
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

SYTL2_MOUSE
NC score	0.289823 (rank : 87)	θ value	4.1701e-05 (rank : 95)
Query Neighborhood Hits	214	Target Neighborhood Hits	253	Shared Neighborhood Hits	100
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

MAGI2_HUMAN
NC score	0.286712 (rank : 88)	θ value	1.47974e-10 (rank : 40)
Query Neighborhood Hits	214	Target Neighborhood Hits	373	Shared Neighborhood Hits	45
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

MAGI1_HUMAN
NC score	0.281499 (rank : 89)	θ value	1.33837e-11 (rank : 35)
Query Neighborhood Hits	214	Target Neighborhood Hits	388	Shared Neighborhood Hits	52
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

MAGI1_MOUSE
NC score	0.281108 (rank : 90)	θ value	1.74796e-11 (rank : 38)
Query Neighborhood Hits	214	Target Neighborhood Hits	403	Shared Neighborhood Hits	53
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

SYTL4_HUMAN
NC score	0.279754 (rank : 91)	θ value	0.0148317 (rank : 135)
Query Neighborhood Hits	214	Target Neighborhood Hits	138	Shared Neighborhood Hits	89
SwissProt Accessions	Q96C24, Q5H9J3, Q5JPG8, Q8N9P4, Q9H4R0, Q9H4R1	Gene names	SYTL4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

SYTL1_HUMAN
NC score	0.275798 (rank : 92)	θ value	0.00228821 (rank : 113)
Query Neighborhood Hits	214	Target Neighborhood Hits	227	Shared Neighborhood Hits	91
SwissProt Accessions	Q8IYJ3, Q96BB6, Q96GU6, Q96S89, Q96SI0	Gene names	SYTL1, SLP1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1) (SB146).

SYTL4_MOUSE
NC score	0.275411 (rank : 93)	θ value	0.0563607 (rank : 149)
Query Neighborhood Hits	214	Target Neighborhood Hits	137	Shared Neighborhood Hits	91
SwissProt Accessions	Q9R0Q1, Q8R321, Q9R0Q0	Gene names	Sytl4, Slp4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

SYTL5_MOUSE
NC score	0.274178 (rank : 94)	θ value	0.0193708 (rank : 138)
Query Neighborhood Hits	214	Target Neighborhood Hits	154	Shared Neighborhood Hits	109
SwissProt Accessions	Q80T23, Q812E5	Gene names	Sytl5, Slp5
Domain Architecture
Description	Synaptotagmin-like protein 5.

SYT15_HUMAN
NC score	0.271746 (rank : 95)	θ value	0.0563607 (rank : 148)
Query Neighborhood Hits	214	Target Neighborhood Hits	112	Shared Neighborhood Hits	91
SwissProt Accessions	Q9BQS2, Q7Z439, Q7Z440	Gene names	SYT15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV) (Chr10Syt).

BAIP3_MOUSE
NC score	0.271537 (rank : 96)	θ value	0.00509761 (rank : 120)
Query Neighborhood Hits	214	Target Neighborhood Hits	112	Shared Neighborhood Hits	94
SwissProt Accessions	Q80TT2, Q6RUT4	Gene names	Baiap3, Gm937, Kiaa0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

SYTL5_HUMAN
NC score	0.270347 (rank : 97)	θ value	0.00228821 (rank : 114)
Query Neighborhood Hits	214	Target Neighborhood Hits	237	Shared Neighborhood Hits	107
SwissProt Accessions	Q8TDW5	Gene names	SYTL5, SLP5
Domain Architecture
Description	Synaptotagmin-like protein 5.

SYTL1_MOUSE
NC score	0.269827 (rank : 98)	θ value	0.00035302 (rank : 103)
Query Neighborhood Hits	214	Target Neighborhood Hits	314	Shared Neighborhood Hits	84
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

BAIP3_HUMAN
NC score	0.262022 (rank : 99)	θ value	0.0193708 (rank : 136)
Query Neighborhood Hits	214	Target Neighborhood Hits	108	Shared Neighborhood Hits	83
SwissProt Accessions	O94812, O94839, Q2M226, Q658J2, Q76N05, Q96RZ3, Q9UJK1	Gene names	BAIAP3, KIAA0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

RIMS2_HUMAN
NC score	0.261996 (rank : 100)	θ value	0.00509761 (rank : 122)
Query Neighborhood Hits	214	Target Neighborhood Hits	342	Shared Neighborhood Hits	113
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
NC score	0.259694 (rank : 101)	θ value	0.00298849 (rank : 116)
Query Neighborhood Hits	214	Target Neighborhood Hits	376	Shared Neighborhood Hits	114
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

PA24D_MOUSE
NC score	0.258006 (rank : 102)	θ value	4.1701e-05 (rank : 94)
Query Neighborhood Hits	214	Target Neighborhood Hits	100	Shared Neighborhood Hits	89
SwissProt Accessions	Q50L43, Q3TJC5	Gene names	Pla2g4d
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

SYT15_MOUSE
NC score	0.255889 (rank : 103)	θ value	0.125558 (rank : 155)
Query Neighborhood Hits	214	Target Neighborhood Hits	100	Shared Neighborhood Hits	85
SwissProt Accessions	Q8C6N3, Q7TN81, Q7TN82, Q8C999	Gene names	Syt15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV).

PKHA5_HUMAN
NC score	0.255239 (rank : 104)	θ value	1.69304e-06 (rank : 82)
Query Neighborhood Hits	214	Target Neighborhood Hits	455	Shared Neighborhood Hits	44
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

PA24B_MOUSE
NC score	0.253488 (rank : 105)	θ value	1.25267e-09 (rank : 50)
Query Neighborhood Hits	214	Target Neighborhood Hits	102	Shared Neighborhood Hits	82
SwissProt Accessions	Q4QQM1, Q80VV8, Q91W88	Gene names	Pla2g4b
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

PCLO_HUMAN
NC score	0.244793 (rank : 106)	θ value	4.45536e-07 (rank : 75)
Query Neighborhood Hits	214	Target Neighborhood Hits	2046	Shared Neighborhood Hits	139
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SYT8_MOUSE
NC score	0.244126 (rank : 107)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	214	Target Neighborhood Hits	94	Shared Neighborhood Hits	85
SwissProt Accessions	Q9R0N6, Q64366, Q8C6E7	Gene names	Syt8
Domain Architecture
Description	Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII).

SYTL3_MOUSE
NC score	0.243755 (rank : 108)	θ value	0.47712 (rank : 171)
Query Neighborhood Hits	214	Target Neighborhood Hits	110	Shared Neighborhood Hits	78
SwissProt Accessions	Q99N48, Q8C506, Q99N47, Q99N49, Q99N54, Q99N79	Gene names	Sytl3, Slp3
Domain Architecture
Description	Synaptotagmin-like protein 3 (Exophilin-6).

SYT12_MOUSE
NC score	0.241945 (rank : 109)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	214	Target Neighborhood Hits	102	Shared Neighborhood Hits	90
SwissProt Accessions	Q920N7	Gene names	Syt12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

SYT12_HUMAN
NC score	0.240208 (rank : 110)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	214	Target Neighborhood Hits	100	Shared Neighborhood Hits	87
SwissProt Accessions	Q8IV01	Gene names	SYT12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

RIMS1_HUMAN
NC score	0.235665 (rank : 111)	θ value	0.0148317 (rank : 134)
Query Neighborhood Hits	214	Target Neighborhood Hits	437	Shared Neighborhood Hits	97
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

PCLO_MOUSE
NC score	0.234806 (rank : 112)	θ value	1.69304e-06 (rank : 81)
Query Neighborhood Hits	214	Target Neighborhood Hits	2275	Shared Neighborhood Hits	144
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PA24D_HUMAN
NC score	0.234438 (rank : 113)	θ value	0.000461057 (rank : 104)
Query Neighborhood Hits	214	Target Neighborhood Hits	97	Shared Neighborhood Hits	83
SwissProt Accessions	Q86XP0, Q8N176	Gene names	PLA2G4D
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

MYOF_HUMAN
NC score	0.229951 (rank : 114)	θ value	0.00509761 (rank : 121)
Query Neighborhood Hits	214	Target Neighborhood Hits	147	Shared Neighborhood Hits	108
SwissProt Accessions	Q9NZM1, Q9HBU3, Q9NZM0, Q9ULL3, Q9Y4U4	Gene names	FER1L3, KIAA1207, MYOF
Domain Architecture
Description	Myoferlin (Fer-1-like protein 3).

GAS7_HUMAN
NC score	0.229232 (rank : 115)	θ value	0.00869519 (rank : 126)
Query Neighborhood Hits	214	Target Neighborhood Hits	258	Shared Neighborhood Hits	50
SwissProt Accessions	O60861, O43144	Gene names	GAS7, KIAA0394
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

GAS7_MOUSE
NC score	0.227169 (rank : 116)	θ value	0.0113563 (rank : 128)
Query Neighborhood Hits	214	Target Neighborhood Hits	259	Shared Neighborhood Hits	49
SwissProt Accessions	Q60780, Q9QY25, Q9QY26, Q9QY34	Gene names	Gas7
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

SYT13_HUMAN
NC score	0.223864 (rank : 117)	θ value	0.813845 (rank : 178)
Query Neighborhood Hits	214	Target Neighborhood Hits	76	Shared Neighborhood Hits	65
SwissProt Accessions	Q7L8C5, Q9BQS3, Q9H041, Q9P2C0	Gene names	SYT13, KIAA1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

PA24B_HUMAN
NC score	0.218451 (rank : 118)	θ value	1.53129e-07 (rank : 69)
Query Neighborhood Hits	214	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	O95712, Q59GF9, Q8TB10, Q9UKV7	Gene names	PLA2G4B
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

SYT13_MOUSE
NC score	0.216670 (rank : 119)	θ value	1.06291 (rank : 183)
Query Neighborhood Hits	214	Target Neighborhood Hits	69	Shared Neighborhood Hits	64
SwissProt Accessions	Q9EQT6, Q6ZPR2, Q8BRK6	Gene names	Syt13, Kiaa1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

DYSF_HUMAN
NC score	0.211099 (rank : 120)	θ value	0.21417 (rank : 159)
Query Neighborhood Hits	214	Target Neighborhood Hits	170	Shared Neighborhood Hits	120
SwissProt Accessions	O75923, O75696, Q9UEN7	Gene names	DYSF, FER1L1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

PA24E_MOUSE
NC score	0.210356 (rank : 121)	θ value	9.29e-05 (rank : 99)
Query Neighborhood Hits	214	Target Neighborhood Hits	95	Shared Neighborhood Hits	80
SwissProt Accessions	Q50L42, Q8BX44	Gene names	Pla2g4e
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

SYT14_MOUSE
NC score	0.209519 (rank : 122)	θ value	1.38821 (rank : 186)
Query Neighborhood Hits	214	Target Neighborhood Hits	82	Shared Neighborhood Hits	58
SwissProt Accessions	Q7TN84	Gene names	Syt14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

K0528_HUMAN
NC score	0.204893 (rank : 123)	θ value	0.0961366 (rank : 151)
Query Neighborhood Hits	214	Target Neighborhood Hits	96	Shared Neighborhood Hits	81
SwissProt Accessions	Q86YS7, O60280, Q7Z619, Q86SU3	Gene names	KIAA0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

K0528_MOUSE
NC score	0.204729 (rank : 124)	θ value	0.0961366 (rank : 152)
Query Neighborhood Hits	214	Target Neighborhood Hits	102	Shared Neighborhood Hits	82
SwissProt Accessions	Q7TPS5, Q3TQY6, Q6A052, Q80VA1, Q8C0U3, Q8CID5, Q9CS85	Gene names	Kiaa0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

RASA2_HUMAN
NC score	0.202959 (rank : 125)	θ value	0.00665767 (rank : 125)
Query Neighborhood Hits	214	Target Neighborhood Hits	157	Shared Neighborhood Hits	78
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

DYSF_MOUSE
NC score	0.202007 (rank : 126)	θ value	0.0330416 (rank : 142)
Query Neighborhood Hits	214	Target Neighborhood Hits	162	Shared Neighborhood Hits	117
SwissProt Accessions	Q9ESD7, Q9QXC0	Gene names	Dysf, Fer1l1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

RASA2_MOUSE
NC score	0.201053 (rank : 127)	θ value	0.0113563 (rank : 129)
Query Neighborhood Hits	214	Target Neighborhood Hits	159	Shared Neighborhood Hits	79
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

OTOF_HUMAN
NC score	0.198096 (rank : 128)	θ value	0.0148317 (rank : 132)
Query Neighborhood Hits	214	Target Neighborhood Hits	168	Shared Neighborhood Hits	97
SwissProt Accessions	Q9HC10, Q9HC08, Q9HC09, Q9Y650	Gene names	OTOF, FER1L2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

OTOF_MOUSE
NC score	0.197442 (rank : 129)	θ value	0.0193708 (rank : 137)
Query Neighborhood Hits	214	Target Neighborhood Hits	196	Shared Neighborhood Hits	97
SwissProt Accessions	Q9ESF1, Q9ESF2	Gene names	Otof, Fer1l2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

PA24E_HUMAN
NC score	0.197056 (rank : 130)	θ value	0.00134147 (rank : 108)
Query Neighborhood Hits	214	Target Neighborhood Hits	89	Shared Neighborhood Hits	76
SwissProt Accessions	Q3MJ16, Q6ZSC0	Gene names	PLA2G4E
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

SYT14_HUMAN
NC score	0.196677 (rank : 131)	θ value	5.27518 (rank : 207)
Query Neighborhood Hits	214	Target Neighborhood Hits	81	Shared Neighborhood Hits	56
SwissProt Accessions	Q8NB59, Q5THX7, Q707N3, Q707N4, Q707N5, Q707N6, Q707N7	Gene names	SYT14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

RFIP2_HUMAN
NC score	0.195269 (rank : 132)	θ value	0.365318 (rank : 167)
Query Neighborhood Hits	214	Target Neighborhood Hits	97	Shared Neighborhood Hits	74
SwissProt Accessions	Q7L804, Q9Y2F0	Gene names	RAB11FIP2, KIAA0941
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 2 (Rab11-FIP2) (NRip11).

PA24A_MOUSE
NC score	0.191331 (rank : 133)	θ value	0.0961366 (rank : 153)
Query Neighborhood Hits	214	Target Neighborhood Hits	100	Shared Neighborhood Hits	78
SwissProt Accessions	P47713	Gene names	Pla2g4a, Cpla2, Pla2g4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

RASA3_HUMAN
NC score	0.187758 (rank : 134)	θ value	0.0961366 (rank : 154)
Query Neighborhood Hits	214	Target Neighborhood Hits	166	Shared Neighborhood Hits	77
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

PRP40_HUMAN
NC score	0.187482 (rank : 135)	θ value	0.00134147 (rank : 109)
Query Neighborhood Hits	214	Target Neighborhood Hits	442	Shared Neighborhood Hits	41
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

PRP40_MOUSE
NC score	0.186617 (rank : 136)	θ value	0.00134147 (rank : 110)
Query Neighborhood Hits	214	Target Neighborhood Hits	447	Shared Neighborhood Hits	42
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

PA24A_HUMAN
NC score	0.179538 (rank : 137)	θ value	0.62314 (rank : 174)
Query Neighborhood Hits	214	Target Neighborhood Hits	88	Shared Neighborhood Hits	79
SwissProt Accessions	P47712	Gene names	PLA2G4A, CPLA2, PLA2G4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

PA24F_MOUSE
NC score	0.174337 (rank : 138)	θ value	0.00665767 (rank : 123)
Query Neighborhood Hits	214	Target Neighborhood Hits	93	Shared Neighborhood Hits	71
SwissProt Accessions	Q50L41, Q80VQ8, Q80VV9	Gene names	Pla2g4f
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

RIMS4_MOUSE
NC score	0.170106 (rank : 139)	θ value	0.365318 (rank : 168)
Query Neighborhood Hits	214	Target Neighborhood Hits	76	Shared Neighborhood Hits	65
SwissProt Accessions	P60191	Gene names	Rims4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

RIMS4_HUMAN
NC score	0.169326 (rank : 140)	θ value	0.47712 (rank : 170)
Query Neighborhood Hits	214	Target Neighborhood Hits	76	Shared Neighborhood Hits	65
SwissProt Accessions	Q9H426, Q5JWT7	Gene names	RIMS4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

RASA3_MOUSE
NC score	0.166338 (rank : 141)	θ value	0.21417 (rank : 161)
Query Neighborhood Hits	214	Target Neighborhood Hits	144	Shared Neighborhood Hits	70
SwissProt Accessions	Q60790	Gene names	Rasa3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) (GapIII).

P3C2B_HUMAN
NC score	0.163516 (rank : 142)	θ value	0.0148317 (rank : 133)
Query Neighborhood Hits	214	Target Neighborhood Hits	148	Shared Neighborhood Hits	78
SwissProt Accessions	O00750, O95666, Q5SW99	Gene names	PIK3C2B
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-beta) (PtdIns-3-kinase C2 beta) (PI3K-C2beta) (C2-PI3K).

STXB4_MOUSE
NC score	0.163429 (rank : 143)	θ value	0.0431538 (rank : 147)
Query Neighborhood Hits	214	Target Neighborhood Hits	629	Shared Neighborhood Hits	47
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

STXB4_HUMAN
NC score	0.162760 (rank : 144)	θ value	0.0431538 (rank : 146)
Query Neighborhood Hits	214	Target Neighborhood Hits	616	Shared Neighborhood Hits	47
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

APBB2_HUMAN
NC score	0.159203 (rank : 145)	θ value	0.00509761 (rank : 118)
Query Neighborhood Hits	214	Target Neighborhood Hits	96	Shared Neighborhood Hits	31
SwissProt Accessions	Q92870, Q8IUI6	Gene names	APBB2, FE65L, FE65L1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2 (Fe65-like protein).

CPNE8_HUMAN
NC score	0.150834 (rank : 146)	θ value	0.62314 (rank : 172)
Query Neighborhood Hits	214	Target Neighborhood Hits	86	Shared Neighborhood Hits	73
SwissProt Accessions	Q86YQ8, Q2TB41	Gene names	CPNE8
Domain Architecture
Description	Copine-8 (Copine VIII).

APBB2_MOUSE
NC score	0.150765 (rank : 147)	θ value	0.00509761 (rank : 119)
Query Neighborhood Hits	214	Target Neighborhood Hits	88	Shared Neighborhood Hits	27
SwissProt Accessions	Q9DBR4, Q6DFX8	Gene names	Apbb2
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2.

PA24F_HUMAN
NC score	0.150075 (rank : 148)	θ value	0.813845 (rank : 177)
Query Neighborhood Hits	214	Target Neighborhood Hits	78	Shared Neighborhood Hits	68
SwissProt Accessions	Q68DD2, Q6ZMC8	Gene names	PLA2G4F
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

CPNE8_MOUSE
NC score	0.148535 (rank : 149)	θ value	0.62314 (rank : 173)
Query Neighborhood Hits	214	Target Neighborhood Hits	85	Shared Neighborhood Hits	72
SwissProt Accessions	Q9DC53, Q9CUZ8	Gene names	Cpne8
Domain Architecture
Description	Copine-8 (Copine VIII).

CPNE5_MOUSE
NC score	0.148042 (rank : 150)	θ value	0.365318 (rank : 166)
Query Neighborhood Hits	214	Target Neighborhood Hits	86	Shared Neighborhood Hits	75
SwissProt Accessions	Q8JZW4	Gene names	Cpne5
Domain Architecture
Description	Copine-5 (Copine V).

CPNE5_HUMAN
NC score	0.147971 (rank : 151)	θ value	0.365318 (rank : 165)
Query Neighborhood Hits	214	Target Neighborhood Hits	88	Shared Neighborhood Hits	75
SwissProt Accessions	Q9HCH3	Gene names	CPNE5, KIAA1599
Domain Architecture
Description	Copine-5 (Copine V).

CPNE3_MOUSE
NC score	0.147038 (rank : 152)	θ value	0.0330416 (rank : 141)
Query Neighborhood Hits	214	Target Neighborhood Hits	90	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BT60, Q5CZX9, Q5DU22	Gene names	Cpne3, Kiaa0636
Domain Architecture
Description	Copine-3 (Copine III).

CPNE3_HUMAN
NC score	0.142010 (rank : 153)	θ value	1.06291 (rank : 181)
Query Neighborhood Hits	214	Target Neighborhood Hits	90	Shared Neighborhood Hits	77
SwissProt Accessions	O75131, Q8IYA1	Gene names	CPNE3, CPN3, KIAA0636
Domain Architecture
Description	Copine-3 (Copine III).

RIMS3_HUMAN
NC score	0.141517 (rank : 154)	θ value	4.03905 (rank : 202)
Query Neighborhood Hits	214	Target Neighborhood Hits	66	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UJD0, Q92511	Gene names	RIMS3, KIAA0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

P3C2A_HUMAN
NC score	0.138428 (rank : 155)	θ value	0.21417 (rank : 160)
Query Neighborhood Hits	214	Target Neighborhood Hits	188	Shared Neighborhood Hits	69
SwissProt Accessions	O00443	Gene names	PIK3C2A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha).

CPNE2_MOUSE
NC score	0.138126 (rank : 156)	θ value	1.81305 (rank : 189)
Query Neighborhood Hits	214	Target Neighborhood Hits	82	Shared Neighborhood Hits	70
SwissProt Accessions	P59108, Q8K1D7	Gene names	Cpne2
Domain Architecture
Description	Copine-2 (Copine II).

CPNE2_HUMAN
NC score	0.135283 (rank : 157)	θ value	4.03905 (rank : 199)
Query Neighborhood Hits	214	Target Neighborhood Hits	75	Shared Neighborhood Hits	69
SwissProt Accessions	Q96FN4, Q68D19, Q86XP9	Gene names	CPNE2
Domain Architecture
Description	Copine-2 (Copine II).

CPNE1_MOUSE
NC score	0.135064 (rank : 158)	θ value	0.279714 (rank : 163)
Query Neighborhood Hits	214	Target Neighborhood Hits	83	Shared Neighborhood Hits	72
SwissProt Accessions	Q8C166, Q925K4, Q925K5	Gene names	Cpne1
Domain Architecture
Description	Copine-1 (Copine I).

P3C2A_MOUSE
NC score	0.133541 (rank : 159)	θ value	1.38821 (rank : 185)
Query Neighborhood Hits	214	Target Neighborhood Hits	181	Shared Neighborhood Hits	69
SwissProt Accessions	Q61194, Q61182	Gene names	Pik3c2a, Cpk
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).

RIMS3_MOUSE
NC score	0.132052 (rank : 160)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	214	Target Neighborhood Hits	67	Shared Neighborhood Hits	60
SwissProt Accessions	Q80U57	Gene names	Rims3, Kiaa0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

ITSN2_HUMAN
NC score	0.128872 (rank : 161)	θ value	8.40245e-06 (rank : 90)
Query Neighborhood Hits	214	Target Neighborhood Hits	1173	Shared Neighborhood Hits	98
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

APBB3_HUMAN
NC score	0.125325 (rank : 162)	θ value	0.0252991 (rank : 139)
Query Neighborhood Hits	214	Target Neighborhood Hits	36	Shared Neighborhood Hits	27
SwissProt Accessions	O95704, Q9NYX6, Q9NYX7, Q9NYX8	Gene names	APBB3, FE65L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 3 (Fe65-like protein 2) (Fe65L2).

APBB3_MOUSE
NC score	0.125023 (rank : 163)	θ value	0.0330416 (rank : 140)
Query Neighborhood Hits	214	Target Neighborhood Hits	32	Shared Neighborhood Hits	26
SwissProt Accessions	Q8R1C9	Gene names	Apbb3
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 3.

ITSN2_MOUSE
NC score	0.120863 (rank : 164)	θ value	8.40245e-06 (rank : 91)
Query Neighborhood Hits	214	Target Neighborhood Hits	1371	Shared Neighborhood Hits	101
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

CPNE1_HUMAN
NC score	0.118435 (rank : 165)	θ value	1.81305 (rank : 188)
Query Neighborhood Hits	214	Target Neighborhood Hits	70	Shared Neighborhood Hits	65
SwissProt Accessions	Q99829, Q6IBL3, Q9H243, Q9NTZ7	Gene names	CPNE1, CPN1
Domain Architecture
Description	Copine-1 (Copine I).

CPNE7_HUMAN
NC score	0.116785 (rank : 166)	θ value	1.81305 (rank : 190)
Query Neighborhood Hits	214	Target Neighborhood Hits	92	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UBL6	Gene names	CPNE7
Domain Architecture
Description	Copine-7 (Copine VII).

SETD2_HUMAN
NC score	0.116731 (rank : 167)	θ value	0.163984 (rank : 157)
Query Neighborhood Hits	214	Target Neighborhood Hits	412	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

PLCD1_HUMAN
NC score	0.114560 (rank : 168)	θ value	0.00869519 (rank : 127)
Query Neighborhood Hits	214	Target Neighborhood Hits	93	Shared Neighborhood Hits	55
SwissProt Accessions	P51178	Gene names	PLCD1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

KPCG_MOUSE
NC score	0.113325 (rank : 169)	θ value	7.34386e-10 (rank : 45)
Query Neighborhood Hits	214	Target Neighborhood Hits	1123	Shared Neighborhood Hits	119
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

ITSN1_HUMAN
NC score	0.112639 (rank : 170)	θ value	2.21117e-06 (rank : 83)
Query Neighborhood Hits	214	Target Neighborhood Hits	1757	Shared Neighborhood Hits	111
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN1_MOUSE
NC score	0.112613 (rank : 171)	θ value	2.21117e-06 (rank : 84)
Query Neighborhood Hits	214	Target Neighborhood Hits	1669	Shared Neighborhood Hits	112
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

KPCG_HUMAN
NC score	0.112557 (rank : 172)	θ value	1.25267e-09 (rank : 49)
Query Neighborhood Hits	214	Target Neighborhood Hits	1126	Shared Neighborhood Hits	119
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

CPNE6_HUMAN
NC score	0.111412 (rank : 173)	θ value	0.279714 (rank : 164)
Query Neighborhood Hits	214	Target Neighborhood Hits	85	Shared Neighborhood Hits	71
SwissProt Accessions	O95741, Q53HA6, Q8WVG1	Gene names	CPNE6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

CPNE6_MOUSE
NC score	0.110810 (rank : 174)	θ value	0.47712 (rank : 169)
Query Neighborhood Hits	214	Target Neighborhood Hits	87	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Z140	Gene names	Cpne6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

KPCA_HUMAN
NC score	0.110617 (rank : 175)	θ value	1.25267e-09 (rank : 48)
Query Neighborhood Hits	214	Target Neighborhood Hits	1070	Shared Neighborhood Hits	121
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

TOLIP_MOUSE
NC score	0.110583 (rank : 176)	θ value	0.62314 (rank : 176)
Query Neighborhood Hits	214	Target Neighborhood Hits	24	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QZ06, Q543N1, Q9D5P5	Gene names	Tollip
Domain Architecture
Description	Toll-interacting protein.

KPCA_MOUSE
NC score	0.108280 (rank : 177)	θ value	7.34386e-10 (rank : 44)
Query Neighborhood Hits	214	Target Neighborhood Hits	1067	Shared Neighborhood Hits	121
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KPCB_MOUSE
NC score	0.106354 (rank : 178)	θ value	7.59969e-07 (rank : 77)
Query Neighborhood Hits	214	Target Neighborhood Hits	1117	Shared Neighborhood Hits	121
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

TAC2N_HUMAN
NC score	0.105371 (rank : 179)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	214	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	Q8N9U0	Gene names	MTAC2D1, C14orf47
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

KPCB_HUMAN
NC score	0.104830 (rank : 180)	θ value	7.59969e-07 (rank : 76)
Query Neighborhood Hits	214	Target Neighborhood Hits	1121	Shared Neighborhood Hits	121
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

RHG12_MOUSE
NC score	0.102934 (rank : 181)	θ value	0.00102713 (rank : 107)
Query Neighborhood Hits	214	Target Neighborhood Hits	204	Shared Neighborhood Hits	33
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

TOLIP_HUMAN
NC score	0.102635 (rank : 182)	θ value	0.813845 (rank : 179)
Query Neighborhood Hits	214	Target Neighborhood Hits	20	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H0E2, Q9H9E6, Q9UJ69	Gene names	TOLLIP
Domain Architecture
Description	Toll-interacting protein.

TAC2N_MOUSE
NC score	0.102514 (rank : 183)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	214	Target Neighborhood Hits	43	Shared Neighborhood Hits	33
SwissProt Accessions	Q91XT6, Q9D4A0	Gene names	Mtac2d1
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

DRP2_HUMAN
NC score	0.098518 (rank : 184)	θ value	0.0736092 (rank : 150)
Query Neighborhood Hits	214	Target Neighborhood Hits	186	Shared Neighborhood Hits	25
SwissProt Accessions	Q13474	Gene names	DRP2
Domain Architecture
Description	Dystrophin-related protein 2.

K1333_MOUSE
NC score	0.095465 (rank : 185)	θ value	0.00298849 (rank : 115)
Query Neighborhood Hits	214	Target Neighborhood Hits	53	Shared Neighborhood Hits	13
SwissProt Accessions	Q5RJY2, Q6ZPT7, Q8BNA4	Gene names	Kiaa1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

CPNE4_HUMAN
NC score	0.093305 (rank : 186)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	214	Target Neighborhood Hits	70	Shared Neighborhood Hits	64
SwissProt Accessions	Q96A23, Q8TEX1	Gene names	CPNE4
Domain Architecture
Description	Copine-4 (Copine IV) (Copine-8).

CPNE4_MOUSE
NC score	0.092657 (rank : 187)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	214	Target Neighborhood Hits	67	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BLR2	Gene names	Cpne4
Domain Architecture	No domain graphic available
Description	Copine-4 (Copine IV).

WBP4_MOUSE
NC score	0.092204 (rank : 188)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	214	Target Neighborhood Hits	100	Shared Neighborhood Hits	30
SwissProt Accessions	Q61048, Q8K1Z9, Q9CS45	Gene names	Wbp4, Fbp21, Fnbp21
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21).

RGS3_HUMAN
NC score	0.089876 (rank : 189)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	214	Target Neighborhood Hits	1375	Shared Neighborhood Hits	82
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RHG12_HUMAN
NC score	0.088402 (rank : 190)	θ value	2.36792 (rank : 192)
Query Neighborhood Hits	214	Target Neighborhood Hits	190	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

PLCD1_MOUSE
NC score	0.086366 (rank : 191)	θ value	0.163984 (rank : 156)
Query Neighborhood Hits	214	Target Neighborhood Hits	106	Shared Neighborhood Hits	53
SwissProt Accessions	Q8R3B1	Gene names	Plcd1, Plcd
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

TCRG1_HUMAN
NC score	0.084097 (rank : 192)	θ value	0.0330416 (rank : 145)
Query Neighborhood Hits	214	Target Neighborhood Hits	929	Shared Neighborhood Hits	40
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

SRGEF_HUMAN
NC score	0.083774 (rank : 193)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	214	Target Neighborhood Hits	33	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UGK8, Q9UGK9	Gene names	SERGEF, DELGEF, GNEFR
Domain Architecture	No domain graphic available
Description	Secretion-regulating guanine nucleotide exchange factor (Guanine nucleotide exchange factor-related protein) (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF).

APBB1_MOUSE
NC score	0.083345 (rank : 194)	θ value	3.0926 (rank : 196)
Query Neighborhood Hits	214	Target Neighborhood Hits	75	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QXJ1, O08642, Q3TPU0, Q8BNF4, Q8BSR9	Gene names	Apbb1, Fe65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

APBB1_HUMAN
NC score	0.082676 (rank : 195)	θ value	3.0926 (rank : 195)
Query Neighborhood Hits	214	Target Neighborhood Hits	62	Shared Neighborhood Hits	23
SwissProt Accessions	O00213, Q96A93	Gene names	APBB1, FE65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

TCRG1_MOUSE
NC score	0.082093 (rank : 196)	θ value	0.21417 (rank : 162)
Query Neighborhood Hits	214	Target Neighborhood Hits	947	Shared Neighborhood Hits	43
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

RFIP1_MOUSE
NC score	0.081833 (rank : 197)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	214	Target Neighborhood Hits	152	Shared Neighborhood Hits	42
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

RPGR_HUMAN
NC score	0.081620 (rank : 198)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	214	Target Neighborhood Hits	279	Shared Neighborhood Hits	9
SwissProt Accessions	Q92834, O00702, O00737, Q8N5T6, Q93039, Q9HD29, Q9UMR1	Gene names	RPGR, RP3, XLRP3
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator.

SRGEF_MOUSE
NC score	0.081264 (rank : 199)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	214	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	Q80YD6, Q9QXB7	Gene names	Sergef, Delgef, Gnefr
Domain Architecture	No domain graphic available
Description	Secretion-regulating guanine nucleotide exchange factor (Guanine nucleotide exchange factor-related protein) (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF).

RCC2_HUMAN
NC score	0.080549 (rank : 200)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	214	Target Neighborhood Hits	36	Shared Neighborhood Hits	6
SwissProt Accessions	Q9P258, Q8IVL9, Q9BSN6, Q9NPV8	Gene names	RCC2, KIAA1470, TD60
Domain Architecture	No domain graphic available
Description	Protein RCC2 (Telophase disk protein of 60 kDa) (RCC1-like protein TD- 60).

RCC2_MOUSE
NC score	0.080010 (rank : 201)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	214	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BK67, Q6ZPQ0	Gene names	Rcc2, Kiaa1470
Domain Architecture	No domain graphic available
Description	Protein RCC2.

RPGR_MOUSE
NC score	0.077377 (rank : 202)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	214	Target Neighborhood Hits	281	Shared Neighborhood Hits	8
SwissProt Accessions	Q9R0X5, O88408, Q9CU92	Gene names	Rpgr
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator (mRpgr).

RCC1_HUMAN
NC score	0.077340 (rank : 203)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	214	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	P18754	Gene names	RCC1, CHC1
Domain Architecture
Description	Regulator of chromosome condensation (Chromosome condensation protein 1) (Cell cycle regulatory protein).

RCC1_MOUSE
NC score	0.075699 (rank : 204)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	214	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VE37, Q3UDB6	Gene names	Rcc1, Chc1
Domain Architecture	No domain graphic available
Description	Regulator of chromosome condensation (Chromosome condensation protein 1).

WBS16_MOUSE
NC score	0.075627 (rank : 205)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	214	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CYF5	Gene names	Wbscr16
Domain Architecture	No domain graphic available
Description	Williams-Beuren syndrome chromosome region 16 protein homolog.

WBS16_HUMAN
NC score	0.073939 (rank : 206)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	214	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q96I51, Q548B1, Q9H0G7	Gene names	WBSCR16
Domain Architecture	No domain graphic available
Description	Williams-Beuren syndrome chromosome region 16 protein (RCC1-like G exchanging factor-like protein).

PA24C_HUMAN
NC score	0.073273 (rank : 207)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	214	Target Neighborhood Hits	13	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UP65, O75457, Q9UG68	Gene names	PLA2G4C
Domain Architecture
Description	Cytosolic phospholipase A2 gamma precursor (EC 3.1.1.4) (cPLA2-gamma) (Phospholipase A2 group IVC).

RFIP1_HUMAN
NC score	0.071251 (rank : 208)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	214	Target Neighborhood Hits	236	Shared Neighborhood Hits	43
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

RCBT2_MOUSE
NC score	0.064412 (rank : 209)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	214	Target Neighborhood Hits	156	Shared Neighborhood Hits	6
SwissProt Accessions	Q99LJ7, Q3TUA3, Q8BMG2	Gene names	Rcbtb2, Chc1l
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 2 (Regulator of chromosome condensation and BTB domain-containing protein 2) (Chromosome condensation 1-like).

RCBT2_HUMAN
NC score	0.063560 (rank : 210)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	214	Target Neighborhood Hits	158	Shared Neighborhood Hits	6
SwissProt Accessions	O95199	Gene names	RCBTB2, CHC1L, RLG
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 2 (Regulator of chromosome condensation and BTB domain-containing protein 2) (Chromosome condensation 1-like) (CHC1-L) (RCC1-like G exchanging factor).

K1333_HUMAN
NC score	0.062952 (rank : 211)	θ value	0.00390308 (rank : 117)
Query Neighborhood Hits	214	Target Neighborhood Hits	50	Shared Neighborhood Hits	9
SwissProt Accessions	Q7L622, Q9BVR2, Q9H9E9, Q9NXC0, Q9P2L3	Gene names	KIAA1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

RCBT1_MOUSE
NC score	0.058801 (rank : 212)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	214	Target Neighborhood Hits	157	Shared Neighborhood Hits	4
SwissProt Accessions	Q6NXM2, Q8BTZ6, Q8BZV0	Gene names	Rcbtb1
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 1 (Regulator of chromosome condensation and BTB domain-containing protein 1).

DGCR8_HUMAN
NC score	0.058769 (rank : 213)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	214	Target Neighborhood Hits	72	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WYQ5, Q6DCB2, Q6MZE9, Q6Y2L0, Q96G39, Q96GP8, Q9H6L8, Q9H6T7, Q9NRW2	Gene names	DGCR8, C22orf12, DGCRK6
Domain Architecture
Description	DGCR8 protein (DiGeorge syndrome critical region 8).

RCBT1_HUMAN
NC score	0.057238 (rank : 214)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	214	Target Neighborhood Hits	158	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NDN9, Q969U9	Gene names	RCBTB1, CLLD7, E4.5
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 1 (Regulator of chromosome condensation and BTB domain-containing protein 1) (Chronic lymphocytic leukemia deletion region gene 7 protein) (CLL deletion region gene 7 protein).

DGCR8_MOUSE
NC score	0.056420 (rank : 215)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	214	Target Neighborhood Hits	70	Shared Neighborhood Hits	12
SwissProt Accessions	Q9EQM6	Gene names	Dgcr8
Domain Architecture	No domain graphic available
Description	DGCR8 protein (DiGeorge syndrome critical region 8 homolog) (Gy1).

CUL7_HUMAN
NC score	0.053380 (rank : 216)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	214	Target Neighborhood Hits	41	Shared Neighborhood Hits	5
SwissProt Accessions	Q14999, Q5T654	Gene names	CUL7, KIAA0076
Domain Architecture
Description	Cullin-7 (CUL-7).

DMD_HUMAN
NC score	0.052258 (rank : 217)	θ value	0.0148317 (rank : 130)
Query Neighborhood Hits	214	Target Neighborhood Hits	1135	Shared Neighborhood Hits	43
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

ALS2_HUMAN
NC score	0.050030 (rank : 218)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	214	Target Neighborhood Hits	121	Shared Neighborhood Hits	6
SwissProt Accessions	Q96Q42, Q8N1E0, Q96PC4, Q96Q41, Q9H973, Q9HCK9	Gene names	ALS2, KIAA1563
Domain Architecture
Description	Alsin (Amyotrophic lateral sclerosis protein 2).

DMD_MOUSE
NC score	0.047083 (rank : 219)	θ value	0.0148317 (rank : 131)
Query Neighborhood Hits	214	Target Neighborhood Hits	1111	Shared Neighborhood Hits	44
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

UTRO_HUMAN
NC score	0.043023 (rank : 220)	θ value	0.163984 (rank : 158)
Query Neighborhood Hits	214	Target Neighborhood Hits	960	Shared Neighborhood Hits	41
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

RPGR1_MOUSE
NC score	0.029219 (rank : 221)	θ value	0.62314 (rank : 175)
Query Neighborhood Hits	214	Target Neighborhood Hits	713	Shared Neighborhood Hits	22
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

RHG09_HUMAN
NC score	0.027494 (rank : 222)	θ value	5.27518 (rank : 206)
Query Neighborhood Hits	214	Target Neighborhood Hits	186	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

RPGR1_HUMAN
NC score	0.018955 (rank : 223)	θ value	2.36792 (rank : 193)
Query Neighborhood Hits	214	Target Neighborhood Hits	578	Shared Neighborhood Hits	19
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

FRS3_HUMAN
NC score	0.016990 (rank : 224)	θ value	4.03905 (rank : 201)
Query Neighborhood Hits	214	Target Neighborhood Hits	76	Shared Neighborhood Hits	6
SwissProt Accessions	O43559, Q5T3D5	Gene names	FRS3
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (Suc1-associated neurotrophic factor target 2) (SNT-2) (FGFR signaling adaptor SNT2).

SEM3E_MOUSE
NC score	0.014780 (rank : 225)	θ value	0.0330416 (rank : 144)
Query Neighborhood Hits	214	Target Neighborhood Hits	76	Shared Neighborhood Hits	5
SwissProt Accessions	P70275, O09078, O09079	Gene names	Sema3e, Semah, Semh
Domain Architecture
Description	Semaphorin-3E precursor (Semaphorin H) (Sema H).

SEM3E_HUMAN
NC score	0.014567 (rank : 226)	θ value	0.0330416 (rank : 143)
Query Neighborhood Hits	214	Target Neighborhood Hits	73	Shared Neighborhood Hits	5
SwissProt Accessions	O15041, Q75M94, Q75M97	Gene names	SEMA3E, KIAA0331
Domain Architecture	No domain graphic available
Description	Semaphorin-3E precursor.

D2HDH_MOUSE
NC score	0.012893 (rank : 227)	θ value	4.03905 (rank : 200)
Query Neighborhood Hits	214	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CIM3, Q3TDF5, Q8BU06	Gene names	D2hgdh
Domain Architecture	No domain graphic available
Description	D-2-hydroxyglutarate dehydrogenase, mitochondrial precursor (EC 1.1.99.-).

CASC5_HUMAN
NC score	0.012277 (rank : 228)	θ value	1.06291 (rank : 180)
Query Neighborhood Hits	214	Target Neighborhood Hits	376	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NG31, Q8NHE1, Q8WXA6, Q9HCK2, Q9NR92	Gene names	CASC5, KIAA1570
Domain Architecture	No domain graphic available
Description	Protein CASC5 (Cancer susceptibility candidate gene 5 protein) (ALL1- fused gene from chromosome 15q14) (AF15q14) (D40/AF15q14 protein).

MINT_HUMAN
NC score	0.010195 (rank : 229)	θ value	8.99809 (rank : 212)
Query Neighborhood Hits	214	Target Neighborhood Hits	1291	Shared Neighborhood Hits	29
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

FA48A_MOUSE
NC score	0.009501 (rank : 230)	θ value	6.88961 (rank : 211)
Query Neighborhood Hits	214	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TT00, Q8BG53, Q9JLS9	Gene names	Fam48a, D3Ertd300e
Domain Architecture	No domain graphic available
Description	Protein FAM48A (p38-interacting protein) (p38IP).

FA48A_HUMAN
NC score	0.008946 (rank : 231)	θ value	6.88961 (rank : 210)
Query Neighborhood Hits	214	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NEM7, Q71RF3, Q9Y6A6	Gene names	FAM48A
Domain Architecture	No domain graphic available
Description	Protein FAM48A (p38-interacting protein) (p38IP).

CHMP7_MOUSE
NC score	0.008631 (rank : 232)	θ value	6.88961 (rank : 209)
Query Neighborhood Hits	214	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R1T1, Q8CFW4	Gene names	Chmp7
Domain Architecture	No domain graphic available
Description	Protein CHMP7.

CHMP7_HUMAN
NC score	0.008482 (rank : 233)	θ value	6.88961 (rank : 208)
Query Neighborhood Hits	214	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WUX9, Q8NDM1, Q9BT50	Gene names	CHMP7
Domain Architecture	No domain graphic available
Description	Protein CHMP7.

LSD1_HUMAN
NC score	0.008210 (rank : 234)	θ value	3.0926 (rank : 197)
Query Neighborhood Hits	214	Target Neighborhood Hits	455	Shared Neighborhood Hits	9
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

SEM3D_HUMAN
NC score	0.006866 (rank : 235)	θ value	8.99809 (rank : 214)
Query Neighborhood Hits	214	Target Neighborhood Hits	104	Shared Neighborhood Hits	6
SwissProt Accessions	O95025, Q6UW77, Q8NCQ1	Gene names	SEMA3D
Domain Architecture
Description	Semaphorin-3D precursor.

PRP16_HUMAN
NC score	0.005719 (rank : 236)	θ value	3.0926 (rank : 198)
Query Neighborhood Hits	214	Target Neighborhood Hits	135	Shared Neighborhood Hits	8
SwissProt Accessions	Q92620, O75212, Q96HN7	Gene names	DHX38, DDX38, KIAA0224, PRP16
Domain Architecture
Description	Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 (EC 3.6.1.-) (ATP-dependent RNA helicase DHX38) (DEAH box protein 38).

M3K9_HUMAN
NC score	0.005449 (rank : 237)	θ value	1.06291 (rank : 182)
Query Neighborhood Hits	214	Target Neighborhood Hits	1123	Shared Neighborhood Hits	15
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

RIPK5_MOUSE
NC score	0.004805 (rank : 238)	θ value	8.99809 (rank : 213)
Query Neighborhood Hits	214	Target Neighborhood Hits	874	Shared Neighborhood Hits	10
SwissProt Accessions	Q6XUX1, Q3ULK4, Q5EBN5, Q8C7D4, Q8C923, Q9CTP7	Gene names	Ripk5
Domain Architecture	No domain graphic available
Description	Receptor-interacting serine/threonine-protein kinase 5 (EC 2.7.11.1) (Dusty protein kinase) (Dusty PK).

1433G_HUMAN
NC score	0.003981 (rank : 239)	θ value	5.27518 (rank : 203)
Query Neighborhood Hits	214	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	P61981, O70457, P35214, Q6FH52, Q9UDP2, Q9UN99	Gene names	YWHAG
Domain Architecture
Description	14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1).

1433G_MOUSE
NC score	0.003981 (rank : 240)	θ value	5.27518 (rank : 204)
Query Neighborhood Hits	214	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	P61982, O70457, P35214, Q3UFD6, Q4FK44, Q9UDP2, Q9UN99	Gene names	Ywhag
Domain Architecture
Description	14-3-3 protein gamma.

ANPRA_HUMAN
NC score	0.003661 (rank : 241)	θ value	1.81305 (rank : 187)
Query Neighborhood Hits	214	Target Neighborhood Hits	612	Shared Neighborhood Hits	13
SwissProt Accessions	P16066, Q6P4Q3	Gene names	NPR1, ANPRA
Domain Architecture
Description	Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor).

CHD8_HUMAN
NC score	0.001800 (rank : 242)	θ value	2.36792 (rank : 191)
Query Neighborhood Hits	214	Target Neighborhood Hits	235	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

MYO15_HUMAN
NC score	0.000026 (rank : 243)	θ value	5.27518 (rank : 205)
Query Neighborhood Hits	214	Target Neighborhood Hits	671	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

STAB1_MOUSE
NC score	-0.002386 (rank : 244)	θ value	2.36792 (rank : 194)
Query Neighborhood Hits	214	Target Neighborhood Hits	566	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

ADA1D_MOUSE
NC score	-0.005863 (rank : 245)	θ value	1.38821 (rank : 184)
Query Neighborhood Hits	214	Target Neighborhood Hits	874	Shared Neighborhood Hits	2
SwissProt Accessions	P97714, Q61619	Gene names	Adra1d, Adra1a, Gpcr8
Domain Architecture
Description	Alpha-1D adrenergic receptor (Alpha 1D-adrenoceptor) (Alpha 1D- adrenoreceptor) (Alpha-1A adrenergic receptor).