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Network neighborhood for query Sequence : WBP4_MOUSE

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WBP4_MOUSE
SwissProt Accessions	Q61048, Q8K1Z9, Q9CS45	Gene names	Wbp4, Fbp21, Fnbp21
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

WBP4_MOUSE
θ value	2.83983e-179 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	100	Target Neighborhood Hits	100	Shared Neighborhood Hits	100
SwissProt Accessions	Q61048, Q8K1Z9, Q9CS45	Gene names	Wbp4, Fbp21, Fnbp21
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21).

WBP4_HUMAN
θ value	2.52267e-127 (rank : 2)	NC score	0.942255 (rank : 2)
Query Neighborhood Hits	100	Target Neighborhood Hits	86	Shared Neighborhood Hits	34
SwissProt Accessions	O75554	Gene names	WBP4, FBP21, FNBP21
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21).

PRP40_HUMAN
θ value	5.08577e-11 (rank : 3)	NC score	0.421886 (rank : 4)
Query Neighborhood Hits	100	Target Neighborhood Hits	442	Shared Neighborhood Hits	49
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

PRP40_MOUSE
θ value	5.08577e-11 (rank : 4)	NC score	0.422915 (rank : 3)
Query Neighborhood Hits	100	Target Neighborhood Hits	447	Shared Neighborhood Hits	49
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

PKCB1_HUMAN
θ value	0.00134147 (rank : 5)	NC score	0.104693 (rank : 27)
Query Neighborhood Hits	100	Target Neighborhood Hits	488	Shared Neighborhood Hits	26
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

TCRG1_HUMAN
θ value	0.00509761 (rank : 6)	NC score	0.184423 (rank : 8)
Query Neighborhood Hits	100	Target Neighborhood Hits	929	Shared Neighborhood Hits	44
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
θ value	0.00509761 (rank : 7)	NC score	0.183994 (rank : 9)
Query Neighborhood Hits	100	Target Neighborhood Hits	947	Shared Neighborhood Hits	44
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

K1688_HUMAN
θ value	0.0148317 (rank : 8)	NC score	0.128420 (rank : 15)
Query Neighborhood Hits	100	Target Neighborhood Hits	217	Shared Neighborhood Hits	15
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

SETD2_HUMAN
θ value	0.0148317 (rank : 9)	NC score	0.133392 (rank : 12)
Query Neighborhood Hits	100	Target Neighborhood Hits	412	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

RU1C_HUMAN
θ value	0.0330416 (rank : 10)	NC score	0.219364 (rank : 5)
Query Neighborhood Hits	100	Target Neighborhood Hits	81	Shared Neighborhood Hits	6
SwissProt Accessions	P09234	Gene names	SNRPC
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

RU1C_MOUSE
θ value	0.0330416 (rank : 11)	NC score	0.218461 (rank : 6)
Query Neighborhood Hits	100	Target Neighborhood Hits	83	Shared Neighborhood Hits	6
SwissProt Accessions	Q62241	Gene names	Snrp1c, Snrpc
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

PIN1_MOUSE
θ value	0.0431538 (rank : 12)	NC score	0.185507 (rank : 7)
Query Neighborhood Hits	100	Target Neighborhood Hits	60	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QUR7, Q543B3	Gene names	Pin1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

IQGA1_HUMAN
θ value	0.0736092 (rank : 13)	NC score	0.130393 (rank : 14)
Query Neighborhood Hits	100	Target Neighborhood Hits	250	Shared Neighborhood Hits	15
SwissProt Accessions	P46940	Gene names	IQGAP1, KIAA0051
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1 (p195).

TRIPC_HUMAN
θ value	0.0961366 (rank : 14)	NC score	0.103513 (rank : 28)
Query Neighborhood Hits	100	Target Neighborhood Hits	319	Shared Neighborhood Hits	26
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

IWS1_HUMAN
θ value	0.125558 (rank : 15)	NC score	0.100104 (rank : 33)
Query Neighborhood Hits	100	Target Neighborhood Hits	1241	Shared Neighborhood Hits	49
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

POT15_HUMAN
θ value	0.125558 (rank : 16)	NC score	0.045243 (rank : 89)
Query Neighborhood Hits	100	Target Neighborhood Hits	893	Shared Neighborhood Hits	32
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

TEX14_MOUSE
θ value	0.125558 (rank : 17)	NC score	0.027545 (rank : 108)
Query Neighborhood Hits	100	Target Neighborhood Hits	1333	Shared Neighborhood Hits	23
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

RBP2_MOUSE
θ value	0.163984 (rank : 18)	NC score	0.030233 (rank : 105)
Query Neighborhood Hits	100	Target Neighborhood Hits	232	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ERU9, Q61992, Q8C9K9	Gene names	Ranbp2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2 (RanBP2).

IQGA1_MOUSE
θ value	0.21417 (rank : 19)	NC score	0.125201 (rank : 16)
Query Neighborhood Hits	100	Target Neighborhood Hits	219	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JKF1	Gene names	Iqgap1
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1.

TXND2_HUMAN
θ value	0.21417 (rank : 20)	NC score	0.065007 (rank : 52)
Query Neighborhood Hits	100	Target Neighborhood Hits	793	Shared Neighborhood Hits	33
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

ANR21_HUMAN
θ value	0.279714 (rank : 21)	NC score	0.042667 (rank : 92)
Query Neighborhood Hits	100	Target Neighborhood Hits	864	Shared Neighborhood Hits	28
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

DGC14_MOUSE
θ value	0.279714 (rank : 22)	NC score	0.091523 (rank : 39)
Query Neighborhood Hits	100	Target Neighborhood Hits	35	Shared Neighborhood Hits	6
SwissProt Accessions	O70279, Q91YX1	Gene names	Dgcr14, Dgsi, Es2, Es2el
Domain Architecture	No domain graphic available
Description	DGCR14 protein (DiGeorge syndrome critical region 14 homolog) (ES2 protein) (Expressed sequence 2 embryonic lethal).

K1688_MOUSE
θ value	0.279714 (rank : 23)	NC score	0.089112 (rank : 40)
Query Neighborhood Hits	100	Target Neighborhood Hits	188	Shared Neighborhood Hits	10
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

PIN1_HUMAN
θ value	0.279714 (rank : 24)	NC score	0.170952 (rank : 10)
Query Neighborhood Hits	100	Target Neighborhood Hits	59	Shared Neighborhood Hits	27
SwissProt Accessions	Q13526	Gene names	PIN1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

TITIN_HUMAN
θ value	0.279714 (rank : 25)	NC score	0.016824 (rank : 121)
Query Neighborhood Hits	100	Target Neighborhood Hits	2923	Shared Neighborhood Hits	36
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

WWOX_HUMAN
θ value	0.279714 (rank : 26)	NC score	0.102602 (rank : 29)
Query Neighborhood Hits	100	Target Neighborhood Hits	115	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NZC7, Q5MYT5, Q96KM3, Q96RF2, Q9BTT8, Q9NPC9, Q9NRF4, Q9NRF5, Q9NRF6, Q9NRK1, Q9NZC5	Gene names	WWOX, FOR, WOX1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-) (Fragile site FRA16D oxidoreductase).

WWOX_MOUSE
θ value	0.279714 (rank : 27)	NC score	0.101674 (rank : 30)
Query Neighborhood Hits	100	Target Neighborhood Hits	118	Shared Neighborhood Hits	28
SwissProt Accessions	Q91WL8, Q8C8J6, Q920Y2, Q9D2B3, Q9D339, Q9JLF5	Gene names	Wwox, Wox1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-).

IQGA2_HUMAN
θ value	0.47712 (rank : 28)	NC score	0.116794 (rank : 24)
Query Neighborhood Hits	100	Target Neighborhood Hits	200	Shared Neighborhood Hits	11
SwissProt Accessions	Q13576	Gene names	IQGAP2
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP2.

ITCH_HUMAN
θ value	0.47712 (rank : 29)	NC score	0.116914 (rank : 23)
Query Neighborhood Hits	100	Target Neighborhood Hits	162	Shared Neighborhood Hits	31
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

ITCH_MOUSE
θ value	0.47712 (rank : 30)	NC score	0.117547 (rank : 22)
Query Neighborhood Hits	100	Target Neighborhood Hits	127	Shared Neighborhood Hits	30
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

NED4L_MOUSE
θ value	0.47712 (rank : 31)	NC score	0.098798 (rank : 34)
Query Neighborhood Hits	100	Target Neighborhood Hits	231	Shared Neighborhood Hits	32
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

OXR1_MOUSE
θ value	0.47712 (rank : 32)	NC score	0.067165 (rank : 47)
Query Neighborhood Hits	100	Target Neighborhood Hits	516	Shared Neighborhood Hits	23
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

CALD1_HUMAN
θ value	0.62314 (rank : 33)	NC score	0.050999 (rank : 81)
Query Neighborhood Hits	100	Target Neighborhood Hits	959	Shared Neighborhood Hits	33
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

NSD1_MOUSE
θ value	0.62314 (rank : 34)	NC score	0.060220 (rank : 58)
Query Neighborhood Hits	100	Target Neighborhood Hits	472	Shared Neighborhood Hits	15
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

WWP2_HUMAN
θ value	0.62314 (rank : 35)	NC score	0.118030 (rank : 21)
Query Neighborhood Hits	100	Target Neighborhood Hits	177	Shared Neighborhood Hits	34
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

WWP2_MOUSE
θ value	0.62314 (rank : 36)	NC score	0.118548 (rank : 20)
Query Neighborhood Hits	100	Target Neighborhood Hits	118	Shared Neighborhood Hits	33
SwissProt Accessions	Q9DBH0, Q8BTG4, Q923F6	Gene names	Wwp2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2).

IWS1_MOUSE
θ value	0.813845 (rank : 37)	NC score	0.094164 (rank : 36)
Query Neighborhood Hits	100	Target Neighborhood Hits	1258	Shared Neighborhood Hits	49
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

NFH_MOUSE
θ value	0.813845 (rank : 38)	NC score	0.040910 (rank : 94)
Query Neighborhood Hits	100	Target Neighborhood Hits	2247	Shared Neighborhood Hits	54
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SPTN5_HUMAN
θ value	0.813845 (rank : 39)	NC score	0.019667 (rank : 117)
Query Neighborhood Hits	100	Target Neighborhood Hits	674	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

IQGA3_HUMAN
θ value	1.06291 (rank : 40)	NC score	0.123995 (rank : 17)
Query Neighborhood Hits	100	Target Neighborhood Hits	125	Shared Neighborhood Hits	12
SwissProt Accessions	Q86VI3	Gene names	IQGAP3
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP3.

JHD2C_HUMAN
θ value	1.06291 (rank : 41)	NC score	0.030526 (rank : 103)
Query Neighborhood Hits	100	Target Neighborhood Hits	279	Shared Neighborhood Hits	13
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

MAP1B_HUMAN
θ value	1.06291 (rank : 42)	NC score	0.072749 (rank : 45)
Query Neighborhood Hits	100	Target Neighborhood Hits	903	Shared Neighborhood Hits	35
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

POTE8_HUMAN
θ value	1.06291 (rank : 43)	NC score	0.036018 (rank : 97)
Query Neighborhood Hits	100	Target Neighborhood Hits	337	Shared Neighborhood Hits	9
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

PSIP1_MOUSE
θ value	1.06291 (rank : 44)	NC score	0.065446 (rank : 51)
Query Neighborhood Hits	100	Target Neighborhood Hits	313	Shared Neighborhood Hits	25
SwissProt Accessions	Q99JF8, Q3TEJ7, Q3TTD7, Q3UTA1, Q80WQ7, Q99JF7, Q99LR4, Q9CT03	Gene names	Psip1, Ledgf
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (mLEDGF).

RHG12_HUMAN
θ value	1.06291 (rank : 45)	NC score	0.084388 (rank : 42)
Query Neighborhood Hits	100	Target Neighborhood Hits	190	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

NED4L_HUMAN
θ value	1.38821 (rank : 46)	NC score	0.100613 (rank : 31)
Query Neighborhood Hits	100	Target Neighborhood Hits	238	Shared Neighborhood Hits	33
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

RHG12_MOUSE
θ value	1.38821 (rank : 47)	NC score	0.094092 (rank : 37)
Query Neighborhood Hits	100	Target Neighborhood Hits	204	Shared Neighborhood Hits	32
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

SEC63_MOUSE
θ value	1.38821 (rank : 48)	NC score	0.067163 (rank : 48)
Query Neighborhood Hits	100	Target Neighborhood Hits	601	Shared Neighborhood Hits	27
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

2A5D_HUMAN
θ value	1.81305 (rank : 49)	NC score	0.020485 (rank : 115)
Query Neighborhood Hits	100	Target Neighborhood Hits	59	Shared Neighborhood Hits	3
SwissProt Accessions	Q14738, O00494, O00696, Q15171	Gene names	PPP2R5D
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PP2A, B subunit, B' delta isoform) (PP2A, B subunit, B56 delta isoform) (PP2A, B subunit, PR61 delta isoform) (PP2A, B subunit, R5 delta isoform).

AFF4_MOUSE
θ value	1.81305 (rank : 50)	NC score	0.052218 (rank : 78)
Query Neighborhood Hits	100	Target Neighborhood Hits	581	Shared Neighborhood Hits	26
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

YAP1_MOUSE
θ value	1.81305 (rank : 51)	NC score	0.112659 (rank : 26)
Query Neighborhood Hits	100	Target Neighborhood Hits	96	Shared Neighborhood Hits	30
SwissProt Accessions	P46938, Q52KJ5	Gene names	Yap1, Yap, Yap65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

AFF2_MOUSE
θ value	2.36792 (rank : 52)	NC score	0.044678 (rank : 90)
Query Neighborhood Hits	100	Target Neighborhood Hits	225	Shared Neighborhood Hits	15
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

MPP8_HUMAN
θ value	2.36792 (rank : 53)	NC score	0.042687 (rank : 91)
Query Neighborhood Hits	100	Target Neighborhood Hits	948	Shared Neighborhood Hits	31
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

NOLC1_HUMAN
θ value	2.36792 (rank : 54)	NC score	0.064078 (rank : 53)
Query Neighborhood Hits	100	Target Neighborhood Hits	452	Shared Neighborhood Hits	28
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

SMUF2_HUMAN
θ value	2.36792 (rank : 55)	NC score	0.094245 (rank : 35)
Query Neighborhood Hits	100	Target Neighborhood Hits	142	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

STXB4_MOUSE
θ value	2.36792 (rank : 56)	NC score	0.048806 (rank : 86)
Query Neighborhood Hits	100	Target Neighborhood Hits	629	Shared Neighborhood Hits	29
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

DGC14_HUMAN
θ value	3.0926 (rank : 57)	NC score	0.063847 (rank : 55)
Query Neighborhood Hits	100	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q96DF8, Q9BTZ4	Gene names	DGCR14, DGSI, ES2
Domain Architecture	No domain graphic available
Description	DGCR14 protein (DiGeorge syndrome critical region 14) (ES2 protein).

HXC10_MOUSE
θ value	3.0926 (rank : 58)	NC score	0.009032 (rank : 129)
Query Neighborhood Hits	100	Target Neighborhood Hits	417	Shared Neighborhood Hits	6
SwissProt Accessions	P31257, P31312, Q7TMT7	Gene names	Hoxc10, Hox-3.6, Hoxc-10
Domain Architecture	No domain graphic available
Description	Homeobox protein Hox-C10 (Hox-3.6).

MNDA_HUMAN
θ value	3.0926 (rank : 59)	NC score	0.023686 (rank : 110)
Query Neighborhood Hits	100	Target Neighborhood Hits	76	Shared Neighborhood Hits	5
SwissProt Accessions	P41218	Gene names	MNDA
Domain Architecture
Description	Myeloid cell nuclear differentiation antigen.

NALP5_MOUSE
θ value	3.0926 (rank : 60)	NC score	0.039321 (rank : 96)
Query Neighborhood Hits	100	Target Neighborhood Hits	560	Shared Neighborhood Hits	33
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

PINL_HUMAN
θ value	3.0926 (rank : 61)	NC score	0.149324 (rank : 11)
Query Neighborhood Hits	100	Target Neighborhood Hits	47	Shared Neighborhood Hits	25
SwissProt Accessions	O15428	Gene names	PIN1L
Domain Architecture
Description	PIN1-like protein.

RHG09_HUMAN
θ value	3.0926 (rank : 62)	NC score	0.040827 (rank : 95)
Query Neighborhood Hits	100	Target Neighborhood Hits	186	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

ANKZ1_MOUSE
θ value	4.03905 (rank : 63)	NC score	0.031286 (rank : 102)
Query Neighborhood Hits	100	Target Neighborhood Hits	208	Shared Neighborhood Hits	7
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

ARI4A_HUMAN
θ value	4.03905 (rank : 64)	NC score	0.048573 (rank : 87)
Query Neighborhood Hits	100	Target Neighborhood Hits	434	Shared Neighborhood Hits	25
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

PRG4_MOUSE
θ value	4.03905 (rank : 65)	NC score	0.034522 (rank : 98)
Query Neighborhood Hits	100	Target Neighborhood Hits	624	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SEC63_HUMAN
θ value	4.03905 (rank : 66)	NC score	0.062714 (rank : 57)
Query Neighborhood Hits	100	Target Neighborhood Hits	586	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

ZC11A_MOUSE
θ value	4.03905 (rank : 67)	NC score	0.032516 (rank : 99)
Query Neighborhood Hits	100	Target Neighborhood Hits	216	Shared Neighborhood Hits	11
SwissProt Accessions	Q6NZF1, Q6NXW9, Q6PDR6, Q80TU7, Q8C5L5, Q99JN6	Gene names	Zc3h11a, Kiaa0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

ACINU_HUMAN
θ value	5.27518 (rank : 68)	NC score	0.053273 (rank : 76)
Query Neighborhood Hits	100	Target Neighborhood Hits	828	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

AP3B1_HUMAN
θ value	5.27518 (rank : 69)	NC score	0.031952 (rank : 101)
Query Neighborhood Hits	100	Target Neighborhood Hits	283	Shared Neighborhood Hits	24
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

CAC1F_MOUSE
θ value	5.27518 (rank : 70)	NC score	0.008314 (rank : 130)
Query Neighborhood Hits	100	Target Neighborhood Hits	142	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CENPF_HUMAN
θ value	5.27518 (rank : 71)	NC score	0.018590 (rank : 119)
Query Neighborhood Hits	100	Target Neighborhood Hits	1932	Shared Neighborhood Hits	38
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

GAS7_HUMAN
θ value	5.27518 (rank : 72)	NC score	0.122599 (rank : 18)
Query Neighborhood Hits	100	Target Neighborhood Hits	258	Shared Neighborhood Hits	34
SwissProt Accessions	O60861, O43144	Gene names	GAS7, KIAA0394
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

LBN_HUMAN
θ value	5.27518 (rank : 73)	NC score	0.017518 (rank : 120)
Query Neighborhood Hits	100	Target Neighborhood Hits	308	Shared Neighborhood Hits	6
SwissProt Accessions	Q86UK5, Q86YT3, Q86YT4, Q8NG49	Gene names	EVC2, LBN
Domain Architecture	No domain graphic available
Description	Limbin.

NNP1_MOUSE
θ value	5.27518 (rank : 74)	NC score	0.025604 (rank : 109)
Query Neighborhood Hits	100	Target Neighborhood Hits	47	Shared Neighborhood Hits	6
SwissProt Accessions	P56183, O35712, Q9ERE1, Q9JI07, Q9JK67, Q9JKU2	Gene names	Nnp1
Domain Architecture
Description	NNP-1 protein (Novel nuclear protein 1) (Nop52).

SMRC2_HUMAN
θ value	5.27518 (rank : 75)	NC score	0.028450 (rank : 106)
Query Neighborhood Hits	100	Target Neighborhood Hits	499	Shared Neighborhood Hits	23
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

WWP1_MOUSE
θ value	5.27518 (rank : 76)	NC score	0.119079 (rank : 19)
Query Neighborhood Hits	100	Target Neighborhood Hits	138	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

ARMC4_HUMAN
θ value	6.88961 (rank : 77)	NC score	0.021419 (rank : 113)
Query Neighborhood Hits	100	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q5T2S8, Q9H0C0	Gene names	ARMC4
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 4.

DCDC2_MOUSE
θ value	6.88961 (rank : 78)	NC score	0.022772 (rank : 112)
Query Neighborhood Hits	100	Target Neighborhood Hits	247	Shared Neighborhood Hits	16
SwissProt Accessions	Q5DU00, Q5SZU0, Q80Y99	Gene names	Dcdc2, Kiaa1154
Domain Architecture	No domain graphic available
Description	Doublecortin domain-containing protein 2.

DDX21_MOUSE
θ value	6.88961 (rank : 79)	NC score	0.015610 (rank : 123)
Query Neighborhood Hits	100	Target Neighborhood Hits	350	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

GABPA_HUMAN
θ value	6.88961 (rank : 80)	NC score	0.009293 (rank : 127)
Query Neighborhood Hits	100	Target Neighborhood Hits	55	Shared Neighborhood Hits	3
SwissProt Accessions	Q06546, Q12939	Gene names	GABPA, E4TF1A
Domain Architecture
Description	GA-binding protein alpha chain (GABP-subunit alpha) (Transcription factor E4TF1-60) (Nuclear respiratory factor 2 subunit alpha).

GAS7_MOUSE
θ value	6.88961 (rank : 81)	NC score	0.130706 (rank : 13)
Query Neighborhood Hits	100	Target Neighborhood Hits	259	Shared Neighborhood Hits	35
SwissProt Accessions	Q60780, Q9QY25, Q9QY26, Q9QY34	Gene names	Gas7
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

NEDD4_MOUSE
θ value	6.88961 (rank : 82)	NC score	0.100148 (rank : 32)
Query Neighborhood Hits	100	Target Neighborhood Hits	212	Shared Neighborhood Hits	31
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

NFM_HUMAN
θ value	6.88961 (rank : 83)	NC score	0.030465 (rank : 104)
Query Neighborhood Hits	100	Target Neighborhood Hits	1328	Shared Neighborhood Hits	44
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

RNF25_HUMAN
θ value	6.88961 (rank : 84)	NC score	0.020118 (rank : 116)
Query Neighborhood Hits	100	Target Neighborhood Hits	163	Shared Neighborhood Hits	5
SwissProt Accessions	Q96BH1, Q9H874	Gene names	RNF25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-).

TCF8_HUMAN
θ value	6.88961 (rank : 85)	NC score	0.005367 (rank : 131)
Query Neighborhood Hits	100	Target Neighborhood Hits	1057	Shared Neighborhood Hits	19
SwissProt Accessions	P37275, Q12924, Q13800	Gene names	TCF8, AREB6
Domain Architecture
Description	Transcription factor 8 (NIL-2-A zinc finger protein) (Negative regulator of IL2).

WASF2_MOUSE
θ value	6.88961 (rank : 86)	NC score	0.015155 (rank : 124)
Query Neighborhood Hits	100	Target Neighborhood Hits	315	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

WWP1_HUMAN
θ value	6.88961 (rank : 87)	NC score	0.114104 (rank : 25)
Query Neighborhood Hits	100	Target Neighborhood Hits	262	Shared Neighborhood Hits	36
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

BPA1_MOUSE
θ value	8.99809 (rank : 88)	NC score	0.010143 (rank : 126)
Query Neighborhood Hits	100	Target Neighborhood Hits	1477	Shared Neighborhood Hits	25
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CENPB_HUMAN
θ value	8.99809 (rank : 89)	NC score	0.032009 (rank : 100)
Query Neighborhood Hits	100	Target Neighborhood Hits	133	Shared Neighborhood Hits	19
SwissProt Accessions	P07199	Gene names	CENPB
Domain Architecture
Description	Major centromere autoantigen B (Centromere protein B) (CENP-B).

DC1I2_HUMAN
θ value	8.99809 (rank : 90)	NC score	0.009157 (rank : 128)
Query Neighborhood Hits	100	Target Neighborhood Hits	201	Shared Neighborhood Hits	4
SwissProt Accessions	Q13409, Q96NG7, Q96S87, Q9BXZ5, Q9NT58	Gene names	DYNC1I2, DNCI2, DNCIC2
Domain Architecture
Description	Cytoplasmic dynein 1 intermediate chain 2 (Dynein intermediate chain 2, cytosolic) (DH IC-2) (Cytoplasmic dynein intermediate chain 2).

ENAH_MOUSE
θ value	8.99809 (rank : 91)	NC score	0.019121 (rank : 118)
Query Neighborhood Hits	100	Target Neighborhood Hits	919	Shared Neighborhood Hits	19
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

ENAM_MOUSE
θ value	8.99809 (rank : 92)	NC score	0.023357 (rank : 111)
Query Neighborhood Hits	100	Target Neighborhood Hits	229	Shared Neighborhood Hits	10
SwissProt Accessions	O55196	Gene names	Enam
Domain Architecture	No domain graphic available
Description	Enamelin precursor.

K1024_MOUSE
θ value	8.99809 (rank : 93)	NC score	0.016345 (rank : 122)
Query Neighborhood Hits	100	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K3V7, Q69ZS9	Gene names	Kiaa1024
Domain Architecture
Description	UPF0258 protein KIAA1024 (Protein DD1).

NSD1_HUMAN
θ value	8.99809 (rank : 94)	NC score	0.048110 (rank : 88)
Query Neighborhood Hits	100	Target Neighborhood Hits	427	Shared Neighborhood Hits	12
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

PEG3_MOUSE
θ value	8.99809 (rank : 95)	NC score	0.001760 (rank : 132)
Query Neighborhood Hits	100	Target Neighborhood Hits	1101	Shared Neighborhood Hits	17
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

SCYBG_MOUSE
θ value	8.99809 (rank : 96)	NC score	0.020536 (rank : 114)
Query Neighborhood Hits	100	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BSU2, Q8VE25, Q9EPB3	Gene names	Cxcl16, Srpsox
Domain Architecture	No domain graphic available
Description	Small inducible cytokine B16 precursor (Transmembrane chemokine CXCL16) (SR-PSOX) (Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein).

SMRC2_MOUSE
θ value	8.99809 (rank : 97)	NC score	0.027994 (rank : 107)
Query Neighborhood Hits	100	Target Neighborhood Hits	487	Shared Neighborhood Hits	24
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

STXB4_HUMAN
θ value	8.99809 (rank : 98)	NC score	0.041019 (rank : 93)
Query Neighborhood Hits	100	Target Neighborhood Hits	616	Shared Neighborhood Hits	27
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

TACC3_HUMAN
θ value	8.99809 (rank : 99)	NC score	0.014193 (rank : 125)
Query Neighborhood Hits	100	Target Neighborhood Hits	779	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

YAP1_HUMAN
θ value	8.99809 (rank : 100)	NC score	0.085363 (rank : 41)
Query Neighborhood Hits	100	Target Neighborhood Hits	173	Shared Neighborhood Hits	29
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

BAG3_MOUSE
θ value	θ > 10 (rank : 101)	NC score	0.051834 (rank : 80)
Query Neighborhood Hits	100	Target Neighborhood Hits	513	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

CYLC2_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.053767 (rank : 74)
Query Neighborhood Hits	100	Target Neighborhood Hits	223	Shared Neighborhood Hits	23
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

DEK_MOUSE
θ value	θ > 10 (rank : 103)	NC score	0.050642 (rank : 84)
Query Neighborhood Hits	100	Target Neighborhood Hits	280	Shared Neighborhood Hits	22
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

HECD2_HUMAN
θ value	θ > 10 (rank : 104)	NC score	0.057813 (rank : 65)
Query Neighborhood Hits	100	Target Neighborhood Hits	41	Shared Neighborhood Hits	11
SwissProt Accessions	Q5U5R9, Q5VZ97, Q5VZ99, Q8TCP5	Gene names	HECTD2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

HECD2_MOUSE
θ value	θ > 10 (rank : 105)	NC score	0.058350 (rank : 62)
Query Neighborhood Hits	100	Target Neighborhood Hits	38	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CDU6, Q8CBQ9	Gene names	Hectd2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

HUWE1_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.065785 (rank : 50)
Query Neighborhood Hits	100	Target Neighborhood Hits	443	Shared Neighborhood Hits	25
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

HUWE1_MOUSE
θ value	θ > 10 (rank : 107)	NC score	0.066293 (rank : 49)
Query Neighborhood Hits	100	Target Neighborhood Hits	406	Shared Neighborhood Hits	24
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

K0317_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.059930 (rank : 60)
Query Neighborhood Hits	100	Target Neighborhood Hits	46	Shared Neighborhood Hits	11
SwissProt Accessions	O15033, Q7LDY1, Q8IYY9	Gene names	KIAA0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

K0317_MOUSE
θ value	θ > 10 (rank : 109)	NC score	0.060116 (rank : 59)
Query Neighborhood Hits	100	Target Neighborhood Hits	43	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CHG5, Q6P9Q1, Q80YC4, Q8C5W5	Gene names	Kiaa0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

LEO1_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.053675 (rank : 75)
Query Neighborhood Hits	100	Target Neighborhood Hits	958	Shared Neighborhood Hits	36
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

MAP1B_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.067220 (rank : 46)
Query Neighborhood Hits	100	Target Neighborhood Hits	977	Shared Neighborhood Hits	37
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

NEDD4_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.092204 (rank : 38)
Query Neighborhood Hits	100	Target Neighborhood Hits	214	Shared Neighborhood Hits	30
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

NKTR_HUMAN
θ value	θ > 10 (rank : 113)	NC score	0.057447 (rank : 68)
Query Neighborhood Hits	100	Target Neighborhood Hits	658	Shared Neighborhood Hits	40
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

RBBP6_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.050731 (rank : 82)
Query Neighborhood Hits	100	Target Neighborhood Hits	1135	Shared Neighborhood Hits	39
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RSF1_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.052093 (rank : 79)
Query Neighborhood Hits	100	Target Neighborhood Hits	539	Shared Neighborhood Hits	32
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

SAV1_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.063903 (rank : 54)
Query Neighborhood Hits	100	Target Neighborhood Hits	51	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H4B6, Q6IA58, Q9H949, Q9HAK9	Gene names	SAV1, WW45
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (hWW45).

SAV1_MOUSE
θ value	θ > 10 (rank : 117)	NC score	0.062968 (rank : 56)
Query Neighborhood Hits	100	Target Neighborhood Hits	48	Shared Neighborhood Hits	21
SwissProt Accessions	Q8VEB2, Q9D9N9, Q9ER46	Gene names	Sav1, Ww45, Wwp3
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (mWW45).

SFRIP_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.053216 (rank : 77)
Query Neighborhood Hits	100	Target Neighborhood Hits	530	Shared Neighborhood Hits	27
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

SMUF1_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.075982 (rank : 44)
Query Neighborhood Hits	100	Target Neighborhood Hits	135	Shared Neighborhood Hits	23
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

SMUF1_MOUSE
θ value	θ > 10 (rank : 120)	NC score	0.078819 (rank : 43)
Query Neighborhood Hits	100	Target Neighborhood Hits	142	Shared Neighborhood Hits	24
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

THOC2_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.050241 (rank : 85)
Query Neighborhood Hits	100	Target Neighborhood Hits	337	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

TRDN_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.050670 (rank : 83)
Query Neighborhood Hits	100	Target Neighborhood Hits	542	Shared Neighborhood Hits	28
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

TXND2_MOUSE
θ value	θ > 10 (rank : 123)	NC score	0.054844 (rank : 73)
Query Neighborhood Hits	100	Target Neighborhood Hits	828	Shared Neighborhood Hits	35
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

UBE3A_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.057909 (rank : 63)
Query Neighborhood Hits	100	Target Neighborhood Hits	49	Shared Neighborhood Hits	11
SwissProt Accessions	Q05086, P78355, Q93066, Q9UEP4, Q9UEP5, Q9UEP6, Q9UEP7, Q9UEP8, Q9UEP9	Gene names	UBE3A, E6AP
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Oncogenic protein-associated protein E6-AP) (Human papillomavirus E6-associated protein) (NY-REN-54 antigen).

UBE3A_MOUSE
θ value	θ > 10 (rank : 125)	NC score	0.056949 (rank : 69)
Query Neighborhood Hits	100	Target Neighborhood Hits	47	Shared Neighborhood Hits	11
SwissProt Accessions	O08759, P97482	Gene names	Ube3a
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (Oncogenic protein- associated protein E6-AP).

UBE3C_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.056410 (rank : 71)
Query Neighborhood Hits	100	Target Neighborhood Hits	51	Shared Neighborhood Hits	11
SwissProt Accessions	Q15386, Q8TC15, Q96CR4, Q9UDU3	Gene names	UBE3C, KIAA0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

UBE3C_MOUSE
θ value	θ > 10 (rank : 127)	NC score	0.056519 (rank : 70)
Query Neighborhood Hits	100	Target Neighborhood Hits	48	Shared Neighborhood Hits	12
SwissProt Accessions	Q80U95, Q8BQZ6, Q8C7W6, Q8CDJ1, Q8VDL5	Gene names	Ube3c, Kiaa0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

WWC1_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.057659 (rank : 66)
Query Neighborhood Hits	100	Target Neighborhood Hits	290	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

WWC1_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.057486 (rank : 67)
Query Neighborhood Hits	100	Target Neighborhood Hits	290	Shared Neighborhood Hits	25
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

WWTR1_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.057840 (rank : 64)
Query Neighborhood Hits	100	Target Neighborhood Hits	76	Shared Neighborhood Hits	23
SwissProt Accessions	Q9GZV5, Q8N3P2, Q9Y3W6	Gene names	WWTR1, TAZ
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

WWTR1_MOUSE
θ value	θ > 10 (rank : 131)	NC score	0.056232 (rank : 72)
Query Neighborhood Hits	100	Target Neighborhood Hits	54	Shared Neighborhood Hits	21
SwissProt Accessions	Q9EPK5, Q99KI4	Gene names	Wwtr1, Taz
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

YTDC1_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.058506 (rank : 61)
Query Neighborhood Hits	100	Target Neighborhood Hits	458	Shared Neighborhood Hits	25
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

Hits sorted by NC score

WBP4_MOUSE
NC score	0.999962 (rank : 1)	θ value	2.83983e-179 (rank : 1)
Query Neighborhood Hits	100	Target Neighborhood Hits	100	Shared Neighborhood Hits	100
SwissProt Accessions	Q61048, Q8K1Z9, Q9CS45	Gene names	Wbp4, Fbp21, Fnbp21
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21).

WBP4_HUMAN
NC score	0.942255 (rank : 2)	θ value	2.52267e-127 (rank : 2)
Query Neighborhood Hits	100	Target Neighborhood Hits	86	Shared Neighborhood Hits	34
SwissProt Accessions	O75554	Gene names	WBP4, FBP21, FNBP21
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21).

PRP40_MOUSE
NC score	0.422915 (rank : 3)	θ value	5.08577e-11 (rank : 4)
Query Neighborhood Hits	100	Target Neighborhood Hits	447	Shared Neighborhood Hits	49
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

PRP40_HUMAN
NC score	0.421886 (rank : 4)	θ value	5.08577e-11 (rank : 3)
Query Neighborhood Hits	100	Target Neighborhood Hits	442	Shared Neighborhood Hits	49
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

RU1C_HUMAN
NC score	0.219364 (rank : 5)	θ value	0.0330416 (rank : 10)
Query Neighborhood Hits	100	Target Neighborhood Hits	81	Shared Neighborhood Hits	6
SwissProt Accessions	P09234	Gene names	SNRPC
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

RU1C_MOUSE
NC score	0.218461 (rank : 6)	θ value	0.0330416 (rank : 11)
Query Neighborhood Hits	100	Target Neighborhood Hits	83	Shared Neighborhood Hits	6
SwissProt Accessions	Q62241	Gene names	Snrp1c, Snrpc
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

PIN1_MOUSE
NC score	0.185507 (rank : 7)	θ value	0.0431538 (rank : 12)
Query Neighborhood Hits	100	Target Neighborhood Hits	60	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QUR7, Q543B3	Gene names	Pin1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

TCRG1_HUMAN
NC score	0.184423 (rank : 8)	θ value	0.00509761 (rank : 6)
Query Neighborhood Hits	100	Target Neighborhood Hits	929	Shared Neighborhood Hits	44
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
NC score	0.183994 (rank : 9)	θ value	0.00509761 (rank : 7)
Query Neighborhood Hits	100	Target Neighborhood Hits	947	Shared Neighborhood Hits	44
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

PIN1_HUMAN
NC score	0.170952 (rank : 10)	θ value	0.279714 (rank : 24)
Query Neighborhood Hits	100	Target Neighborhood Hits	59	Shared Neighborhood Hits	27
SwissProt Accessions	Q13526	Gene names	PIN1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

PINL_HUMAN
NC score	0.149324 (rank : 11)	θ value	3.0926 (rank : 61)
Query Neighborhood Hits	100	Target Neighborhood Hits	47	Shared Neighborhood Hits	25
SwissProt Accessions	O15428	Gene names	PIN1L
Domain Architecture
Description	PIN1-like protein.

SETD2_HUMAN
NC score	0.133392 (rank : 12)	θ value	0.0148317 (rank : 9)
Query Neighborhood Hits	100	Target Neighborhood Hits	412	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

GAS7_MOUSE
NC score	0.130706 (rank : 13)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	100	Target Neighborhood Hits	259	Shared Neighborhood Hits	35
SwissProt Accessions	Q60780, Q9QY25, Q9QY26, Q9QY34	Gene names	Gas7
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

IQGA1_HUMAN
NC score	0.130393 (rank : 14)	θ value	0.0736092 (rank : 13)
Query Neighborhood Hits	100	Target Neighborhood Hits	250	Shared Neighborhood Hits	15
SwissProt Accessions	P46940	Gene names	IQGAP1, KIAA0051
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1 (p195).

K1688_HUMAN
NC score	0.128420 (rank : 15)	θ value	0.0148317 (rank : 8)
Query Neighborhood Hits	100	Target Neighborhood Hits	217	Shared Neighborhood Hits	15
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

IQGA1_MOUSE
NC score	0.125201 (rank : 16)	θ value	0.21417 (rank : 19)
Query Neighborhood Hits	100	Target Neighborhood Hits	219	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JKF1	Gene names	Iqgap1
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1.

IQGA3_HUMAN
NC score	0.123995 (rank : 17)	θ value	1.06291 (rank : 40)
Query Neighborhood Hits	100	Target Neighborhood Hits	125	Shared Neighborhood Hits	12
SwissProt Accessions	Q86VI3	Gene names	IQGAP3
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP3.

GAS7_HUMAN
NC score	0.122599 (rank : 18)	θ value	5.27518 (rank : 72)
Query Neighborhood Hits	100	Target Neighborhood Hits	258	Shared Neighborhood Hits	34
SwissProt Accessions	O60861, O43144	Gene names	GAS7, KIAA0394
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

WWP1_MOUSE
NC score	0.119079 (rank : 19)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	100	Target Neighborhood Hits	138	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

WWP2_MOUSE
NC score	0.118548 (rank : 20)	θ value	0.62314 (rank : 36)
Query Neighborhood Hits	100	Target Neighborhood Hits	118	Shared Neighborhood Hits	33
SwissProt Accessions	Q9DBH0, Q8BTG4, Q923F6	Gene names	Wwp2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2).

WWP2_HUMAN
NC score	0.118030 (rank : 21)	θ value	0.62314 (rank : 35)
Query Neighborhood Hits	100	Target Neighborhood Hits	177	Shared Neighborhood Hits	34
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

ITCH_MOUSE
NC score	0.117547 (rank : 22)	θ value	0.47712 (rank : 30)
Query Neighborhood Hits	100	Target Neighborhood Hits	127	Shared Neighborhood Hits	30
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

ITCH_HUMAN
NC score	0.116914 (rank : 23)	θ value	0.47712 (rank : 29)
Query Neighborhood Hits	100	Target Neighborhood Hits	162	Shared Neighborhood Hits	31
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

IQGA2_HUMAN
NC score	0.116794 (rank : 24)	θ value	0.47712 (rank : 28)
Query Neighborhood Hits	100	Target Neighborhood Hits	200	Shared Neighborhood Hits	11
SwissProt Accessions	Q13576	Gene names	IQGAP2
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP2.

WWP1_HUMAN
NC score	0.114104 (rank : 25)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	100	Target Neighborhood Hits	262	Shared Neighborhood Hits	36
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

YAP1_MOUSE
NC score	0.112659 (rank : 26)	θ value	1.81305 (rank : 51)
Query Neighborhood Hits	100	Target Neighborhood Hits	96	Shared Neighborhood Hits	30
SwissProt Accessions	P46938, Q52KJ5	Gene names	Yap1, Yap, Yap65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

PKCB1_HUMAN
NC score	0.104693 (rank : 27)	θ value	0.00134147 (rank : 5)
Query Neighborhood Hits	100	Target Neighborhood Hits	488	Shared Neighborhood Hits	26
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

TRIPC_HUMAN
NC score	0.103513 (rank : 28)	θ value	0.0961366 (rank : 14)
Query Neighborhood Hits	100	Target Neighborhood Hits	319	Shared Neighborhood Hits	26
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

WWOX_HUMAN
NC score	0.102602 (rank : 29)	θ value	0.279714 (rank : 26)
Query Neighborhood Hits	100	Target Neighborhood Hits	115	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NZC7, Q5MYT5, Q96KM3, Q96RF2, Q9BTT8, Q9NPC9, Q9NRF4, Q9NRF5, Q9NRF6, Q9NRK1, Q9NZC5	Gene names	WWOX, FOR, WOX1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-) (Fragile site FRA16D oxidoreductase).

WWOX_MOUSE
NC score	0.101674 (rank : 30)	θ value	0.279714 (rank : 27)
Query Neighborhood Hits	100	Target Neighborhood Hits	118	Shared Neighborhood Hits	28
SwissProt Accessions	Q91WL8, Q8C8J6, Q920Y2, Q9D2B3, Q9D339, Q9JLF5	Gene names	Wwox, Wox1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-).

NED4L_HUMAN
NC score	0.100613 (rank : 31)	θ value	1.38821 (rank : 46)
Query Neighborhood Hits	100	Target Neighborhood Hits	238	Shared Neighborhood Hits	33
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NEDD4_MOUSE
NC score	0.100148 (rank : 32)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	100	Target Neighborhood Hits	212	Shared Neighborhood Hits	31
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

IWS1_HUMAN
NC score	0.100104 (rank : 33)	θ value	0.125558 (rank : 15)
Query Neighborhood Hits	100	Target Neighborhood Hits	1241	Shared Neighborhood Hits	49
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

NED4L_MOUSE
NC score	0.098798 (rank : 34)	θ value	0.47712 (rank : 31)
Query Neighborhood Hits	100	Target Neighborhood Hits	231	Shared Neighborhood Hits	32
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

SMUF2_HUMAN
NC score	0.094245 (rank : 35)	θ value	2.36792 (rank : 55)
Query Neighborhood Hits	100	Target Neighborhood Hits	142	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

IWS1_MOUSE
NC score	0.094164 (rank : 36)	θ value	0.813845 (rank : 37)
Query Neighborhood Hits	100	Target Neighborhood Hits	1258	Shared Neighborhood Hits	49
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

RHG12_MOUSE
NC score	0.094092 (rank : 37)	θ value	1.38821 (rank : 47)
Query Neighborhood Hits	100	Target Neighborhood Hits	204	Shared Neighborhood Hits	32
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

NEDD4_HUMAN
NC score	0.092204 (rank : 38)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	100	Target Neighborhood Hits	214	Shared Neighborhood Hits	30
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

DGC14_MOUSE
NC score	0.091523 (rank : 39)	θ value	0.279714 (rank : 22)
Query Neighborhood Hits	100	Target Neighborhood Hits	35	Shared Neighborhood Hits	6
SwissProt Accessions	O70279, Q91YX1	Gene names	Dgcr14, Dgsi, Es2, Es2el
Domain Architecture	No domain graphic available
Description	DGCR14 protein (DiGeorge syndrome critical region 14 homolog) (ES2 protein) (Expressed sequence 2 embryonic lethal).

K1688_MOUSE
NC score	0.089112 (rank : 40)	θ value	0.279714 (rank : 23)
Query Neighborhood Hits	100	Target Neighborhood Hits	188	Shared Neighborhood Hits	10
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

YAP1_HUMAN
NC score	0.085363 (rank : 41)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	100	Target Neighborhood Hits	173	Shared Neighborhood Hits	29
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

RHG12_HUMAN
NC score	0.084388 (rank : 42)	θ value	1.06291 (rank : 45)
Query Neighborhood Hits	100	Target Neighborhood Hits	190	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

SMUF1_MOUSE
NC score	0.078819 (rank : 43)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	100	Target Neighborhood Hits	142	Shared Neighborhood Hits	24
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

SMUF1_HUMAN
NC score	0.075982 (rank : 44)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	100	Target Neighborhood Hits	135	Shared Neighborhood Hits	23
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

MAP1B_HUMAN
NC score	0.072749 (rank : 45)	θ value	1.06291 (rank : 42)
Query Neighborhood Hits	100	Target Neighborhood Hits	903	Shared Neighborhood Hits	35
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MAP1B_MOUSE
NC score	0.067220 (rank : 46)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	100	Target Neighborhood Hits	977	Shared Neighborhood Hits	37
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

OXR1_MOUSE
NC score	0.067165 (rank : 47)	θ value	0.47712 (rank : 32)
Query Neighborhood Hits	100	Target Neighborhood Hits	516	Shared Neighborhood Hits	23
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

SEC63_MOUSE
NC score	0.067163 (rank : 48)	θ value	1.38821 (rank : 48)
Query Neighborhood Hits	100	Target Neighborhood Hits	601	Shared Neighborhood Hits	27
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

HUWE1_MOUSE
NC score	0.066293 (rank : 49)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	100	Target Neighborhood Hits	406	Shared Neighborhood Hits	24
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

HUWE1_HUMAN
NC score	0.065785 (rank : 50)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	100	Target Neighborhood Hits	443	Shared Neighborhood Hits	25
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

PSIP1_MOUSE
NC score	0.065446 (rank : 51)	θ value	1.06291 (rank : 44)
Query Neighborhood Hits	100	Target Neighborhood Hits	313	Shared Neighborhood Hits	25
SwissProt Accessions	Q99JF8, Q3TEJ7, Q3TTD7, Q3UTA1, Q80WQ7, Q99JF7, Q99LR4, Q9CT03	Gene names	Psip1, Ledgf
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (mLEDGF).

TXND2_HUMAN
NC score	0.065007 (rank : 52)	θ value	0.21417 (rank : 20)
Query Neighborhood Hits	100	Target Neighborhood Hits	793	Shared Neighborhood Hits	33
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

NOLC1_HUMAN
NC score	0.064078 (rank : 53)	θ value	2.36792 (rank : 54)
Query Neighborhood Hits	100	Target Neighborhood Hits	452	Shared Neighborhood Hits	28
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

SAV1_HUMAN
NC score	0.063903 (rank : 54)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	100	Target Neighborhood Hits	51	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H4B6, Q6IA58, Q9H949, Q9HAK9	Gene names	SAV1, WW45
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (hWW45).

DGC14_HUMAN
NC score	0.063847 (rank : 55)	θ value	3.0926 (rank : 57)
Query Neighborhood Hits	100	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q96DF8, Q9BTZ4	Gene names	DGCR14, DGSI, ES2
Domain Architecture	No domain graphic available
Description	DGCR14 protein (DiGeorge syndrome critical region 14) (ES2 protein).

SAV1_MOUSE
NC score	0.062968 (rank : 56)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	100	Target Neighborhood Hits	48	Shared Neighborhood Hits	21
SwissProt Accessions	Q8VEB2, Q9D9N9, Q9ER46	Gene names	Sav1, Ww45, Wwp3
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (mWW45).

SEC63_HUMAN
NC score	0.062714 (rank : 57)	θ value	4.03905 (rank : 66)
Query Neighborhood Hits	100	Target Neighborhood Hits	586	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

NSD1_MOUSE
NC score	0.060220 (rank : 58)	θ value	0.62314 (rank : 34)
Query Neighborhood Hits	100	Target Neighborhood Hits	472	Shared Neighborhood Hits	15
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

K0317_MOUSE
NC score	0.060116 (rank : 59)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	100	Target Neighborhood Hits	43	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CHG5, Q6P9Q1, Q80YC4, Q8C5W5	Gene names	Kiaa0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

K0317_HUMAN
NC score	0.059930 (rank : 60)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	100	Target Neighborhood Hits	46	Shared Neighborhood Hits	11
SwissProt Accessions	O15033, Q7LDY1, Q8IYY9	Gene names	KIAA0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

YTDC1_HUMAN
NC score	0.058506 (rank : 61)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	100	Target Neighborhood Hits	458	Shared Neighborhood Hits	25
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

HECD2_MOUSE
NC score	0.058350 (rank : 62)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	100	Target Neighborhood Hits	38	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CDU6, Q8CBQ9	Gene names	Hectd2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

UBE3A_HUMAN
NC score	0.057909 (rank : 63)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	100	Target Neighborhood Hits	49	Shared Neighborhood Hits	11
SwissProt Accessions	Q05086, P78355, Q93066, Q9UEP4, Q9UEP5, Q9UEP6, Q9UEP7, Q9UEP8, Q9UEP9	Gene names	UBE3A, E6AP
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Oncogenic protein-associated protein E6-AP) (Human papillomavirus E6-associated protein) (NY-REN-54 antigen).

WWTR1_HUMAN
NC score	0.057840 (rank : 64)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	100	Target Neighborhood Hits	76	Shared Neighborhood Hits	23
SwissProt Accessions	Q9GZV5, Q8N3P2, Q9Y3W6	Gene names	WWTR1, TAZ
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

HECD2_HUMAN
NC score	0.057813 (rank : 65)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	100	Target Neighborhood Hits	41	Shared Neighborhood Hits	11
SwissProt Accessions	Q5U5R9, Q5VZ97, Q5VZ99, Q8TCP5	Gene names	HECTD2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

WWC1_HUMAN
NC score	0.057659 (rank : 66)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	100	Target Neighborhood Hits	290	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

WWC1_MOUSE
NC score	0.057486 (rank : 67)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	100	Target Neighborhood Hits	290	Shared Neighborhood Hits	25
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

NKTR_HUMAN
NC score	0.057447 (rank : 68)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	100	Target Neighborhood Hits	658	Shared Neighborhood Hits	40
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

UBE3A_MOUSE
NC score	0.056949 (rank : 69)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	100	Target Neighborhood Hits	47	Shared Neighborhood Hits	11
SwissProt Accessions	O08759, P97482	Gene names	Ube3a
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (Oncogenic protein- associated protein E6-AP).

UBE3C_MOUSE
NC score	0.056519 (rank : 70)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	100	Target Neighborhood Hits	48	Shared Neighborhood Hits	12
SwissProt Accessions	Q80U95, Q8BQZ6, Q8C7W6, Q8CDJ1, Q8VDL5	Gene names	Ube3c, Kiaa0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

UBE3C_HUMAN
NC score	0.056410 (rank : 71)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	100	Target Neighborhood Hits	51	Shared Neighborhood Hits	11
SwissProt Accessions	Q15386, Q8TC15, Q96CR4, Q9UDU3	Gene names	UBE3C, KIAA0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

WWTR1_MOUSE
NC score	0.056232 (rank : 72)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	100	Target Neighborhood Hits	54	Shared Neighborhood Hits	21
SwissProt Accessions	Q9EPK5, Q99KI4	Gene names	Wwtr1, Taz
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

TXND2_MOUSE
NC score	0.054844 (rank : 73)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	100	Target Neighborhood Hits	828	Shared Neighborhood Hits	35
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

CYLC2_HUMAN
NC score	0.053767 (rank : 74)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	100	Target Neighborhood Hits	223	Shared Neighborhood Hits	23
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

LEO1_HUMAN
NC score	0.053675 (rank : 75)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	100	Target Neighborhood Hits	958	Shared Neighborhood Hits	36
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

ACINU_HUMAN
NC score	0.053273 (rank : 76)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	100	Target Neighborhood Hits	828	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

SFRIP_HUMAN
NC score	0.053216 (rank : 77)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	100	Target Neighborhood Hits	530	Shared Neighborhood Hits	27
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

AFF4_MOUSE
NC score	0.052218 (rank : 78)	θ value	1.81305 (rank : 50)
Query Neighborhood Hits	100	Target Neighborhood Hits	581	Shared Neighborhood Hits	26
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

RSF1_HUMAN
NC score	0.052093 (rank : 79)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	100	Target Neighborhood Hits	539	Shared Neighborhood Hits	32
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

BAG3_MOUSE
NC score	0.051834 (rank : 80)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	100	Target Neighborhood Hits	513	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

CALD1_HUMAN
NC score	0.050999 (rank : 81)	θ value	0.62314 (rank : 33)
Query Neighborhood Hits	100	Target Neighborhood Hits	959	Shared Neighborhood Hits	33
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

RBBP6_HUMAN
NC score	0.050731 (rank : 82)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	100	Target Neighborhood Hits	1135	Shared Neighborhood Hits	39
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

TRDN_HUMAN
NC score	0.050670 (rank : 83)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	100	Target Neighborhood Hits	542	Shared Neighborhood Hits	28
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

DEK_MOUSE
NC score	0.050642 (rank : 84)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	100	Target Neighborhood Hits	280	Shared Neighborhood Hits	22
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

THOC2_HUMAN
NC score	0.050241 (rank : 85)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	100	Target Neighborhood Hits	337	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

STXB4_MOUSE
NC score	0.048806 (rank : 86)	θ value	2.36792 (rank : 56)
Query Neighborhood Hits	100	Target Neighborhood Hits	629	Shared Neighborhood Hits	29
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

ARI4A_HUMAN
NC score	0.048573 (rank : 87)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	100	Target Neighborhood Hits	434	Shared Neighborhood Hits	25
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

NSD1_HUMAN
NC score	0.048110 (rank : 88)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	100	Target Neighborhood Hits	427	Shared Neighborhood Hits	12
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

POT15_HUMAN
NC score	0.045243 (rank : 89)	θ value	0.125558 (rank : 16)
Query Neighborhood Hits	100	Target Neighborhood Hits	893	Shared Neighborhood Hits	32
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

AFF2_MOUSE
NC score	0.044678 (rank : 90)	θ value	2.36792 (rank : 52)
Query Neighborhood Hits	100	Target Neighborhood Hits	225	Shared Neighborhood Hits	15
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

MPP8_HUMAN
NC score	0.042687 (rank : 91)	θ value	2.36792 (rank : 53)
Query Neighborhood Hits	100	Target Neighborhood Hits	948	Shared Neighborhood Hits	31
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

ANR21_HUMAN
NC score	0.042667 (rank : 92)	θ value	0.279714 (rank : 21)
Query Neighborhood Hits	100	Target Neighborhood Hits	864	Shared Neighborhood Hits	28
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

STXB4_HUMAN
NC score	0.041019 (rank : 93)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	100	Target Neighborhood Hits	616	Shared Neighborhood Hits	27
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

NFH_MOUSE
NC score	0.040910 (rank : 94)	θ value	0.813845 (rank : 38)
Query Neighborhood Hits	100	Target Neighborhood Hits	2247	Shared Neighborhood Hits	54
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RHG09_HUMAN
NC score	0.040827 (rank : 95)	θ value	3.0926 (rank : 62)
Query Neighborhood Hits	100	Target Neighborhood Hits	186	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

NALP5_MOUSE
NC score	0.039321 (rank : 96)	θ value	3.0926 (rank : 60)
Query Neighborhood Hits	100	Target Neighborhood Hits	560	Shared Neighborhood Hits	33
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

POTE8_HUMAN
NC score	0.036018 (rank : 97)	θ value	1.06291 (rank : 43)
Query Neighborhood Hits	100	Target Neighborhood Hits	337	Shared Neighborhood Hits	9
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

PRG4_MOUSE
NC score	0.034522 (rank : 98)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	100	Target Neighborhood Hits	624	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

ZC11A_MOUSE
NC score	0.032516 (rank : 99)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	100	Target Neighborhood Hits	216	Shared Neighborhood Hits	11
SwissProt Accessions	Q6NZF1, Q6NXW9, Q6PDR6, Q80TU7, Q8C5L5, Q99JN6	Gene names	Zc3h11a, Kiaa0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

CENPB_HUMAN
NC score	0.032009 (rank : 100)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	100	Target Neighborhood Hits	133	Shared Neighborhood Hits	19
SwissProt Accessions	P07199	Gene names	CENPB
Domain Architecture
Description	Major centromere autoantigen B (Centromere protein B) (CENP-B).

AP3B1_HUMAN
NC score	0.031952 (rank : 101)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	100	Target Neighborhood Hits	283	Shared Neighborhood Hits	24
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

ANKZ1_MOUSE
NC score	0.031286 (rank : 102)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	100	Target Neighborhood Hits	208	Shared Neighborhood Hits	7
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

JHD2C_HUMAN
NC score	0.030526 (rank : 103)	θ value	1.06291 (rank : 41)
Query Neighborhood Hits	100	Target Neighborhood Hits	279	Shared Neighborhood Hits	13
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

NFM_HUMAN
NC score	0.030465 (rank : 104)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	100	Target Neighborhood Hits	1328	Shared Neighborhood Hits	44
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

RBP2_MOUSE
NC score	0.030233 (rank : 105)	θ value	0.163984 (rank : 18)
Query Neighborhood Hits	100	Target Neighborhood Hits	232	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ERU9, Q61992, Q8C9K9	Gene names	Ranbp2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2 (RanBP2).

SMRC2_HUMAN
NC score	0.028450 (rank : 106)	θ value	5.27518 (rank : 75)
Query Neighborhood Hits	100	Target Neighborhood Hits	499	Shared Neighborhood Hits	23
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

SMRC2_MOUSE
NC score	0.027994 (rank : 107)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	100	Target Neighborhood Hits	487	Shared Neighborhood Hits	24
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

TEX14_MOUSE
NC score	0.027545 (rank : 108)	θ value	0.125558 (rank : 17)
Query Neighborhood Hits	100	Target Neighborhood Hits	1333	Shared Neighborhood Hits	23
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

NNP1_MOUSE
NC score	0.025604 (rank : 109)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	100	Target Neighborhood Hits	47	Shared Neighborhood Hits	6
SwissProt Accessions	P56183, O35712, Q9ERE1, Q9JI07, Q9JK67, Q9JKU2	Gene names	Nnp1
Domain Architecture
Description	NNP-1 protein (Novel nuclear protein 1) (Nop52).

MNDA_HUMAN
NC score	0.023686 (rank : 110)	θ value	3.0926 (rank : 59)
Query Neighborhood Hits	100	Target Neighborhood Hits	76	Shared Neighborhood Hits	5
SwissProt Accessions	P41218	Gene names	MNDA
Domain Architecture
Description	Myeloid cell nuclear differentiation antigen.

ENAM_MOUSE
NC score	0.023357 (rank : 111)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	100	Target Neighborhood Hits	229	Shared Neighborhood Hits	10
SwissProt Accessions	O55196	Gene names	Enam
Domain Architecture	No domain graphic available
Description	Enamelin precursor.

DCDC2_MOUSE
NC score	0.022772 (rank : 112)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	100	Target Neighborhood Hits	247	Shared Neighborhood Hits	16
SwissProt Accessions	Q5DU00, Q5SZU0, Q80Y99	Gene names	Dcdc2, Kiaa1154
Domain Architecture	No domain graphic available
Description	Doublecortin domain-containing protein 2.

ARMC4_HUMAN
NC score	0.021419 (rank : 113)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	100	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q5T2S8, Q9H0C0	Gene names	ARMC4
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 4.

SCYBG_MOUSE
NC score	0.020536 (rank : 114)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	100	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BSU2, Q8VE25, Q9EPB3	Gene names	Cxcl16, Srpsox
Domain Architecture	No domain graphic available
Description	Small inducible cytokine B16 precursor (Transmembrane chemokine CXCL16) (SR-PSOX) (Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein).

2A5D_HUMAN
NC score	0.020485 (rank : 115)	θ value	1.81305 (rank : 49)
Query Neighborhood Hits	100	Target Neighborhood Hits	59	Shared Neighborhood Hits	3
SwissProt Accessions	Q14738, O00494, O00696, Q15171	Gene names	PPP2R5D
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PP2A, B subunit, B' delta isoform) (PP2A, B subunit, B56 delta isoform) (PP2A, B subunit, PR61 delta isoform) (PP2A, B subunit, R5 delta isoform).

RNF25_HUMAN
NC score	0.020118 (rank : 116)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	100	Target Neighborhood Hits	163	Shared Neighborhood Hits	5
SwissProt Accessions	Q96BH1, Q9H874	Gene names	RNF25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-).

SPTN5_HUMAN
NC score	0.019667 (rank : 117)	θ value	0.813845 (rank : 39)
Query Neighborhood Hits	100	Target Neighborhood Hits	674	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

ENAH_MOUSE
NC score	0.019121 (rank : 118)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	100	Target Neighborhood Hits	919	Shared Neighborhood Hits	19
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

CENPF_HUMAN
NC score	0.018590 (rank : 119)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	100	Target Neighborhood Hits	1932	Shared Neighborhood Hits	38
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

LBN_HUMAN
NC score	0.017518 (rank : 120)	θ value	5.27518 (rank : 73)
Query Neighborhood Hits	100	Target Neighborhood Hits	308	Shared Neighborhood Hits	6
SwissProt Accessions	Q86UK5, Q86YT3, Q86YT4, Q8NG49	Gene names	EVC2, LBN
Domain Architecture	No domain graphic available
Description	Limbin.

TITIN_HUMAN
NC score	0.016824 (rank : 121)	θ value	0.279714 (rank : 25)
Query Neighborhood Hits	100	Target Neighborhood Hits	2923	Shared Neighborhood Hits	36
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

K1024_MOUSE
NC score	0.016345 (rank : 122)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	100	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K3V7, Q69ZS9	Gene names	Kiaa1024
Domain Architecture
Description	UPF0258 protein KIAA1024 (Protein DD1).

DDX21_MOUSE
NC score	0.015610 (rank : 123)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	100	Target Neighborhood Hits	350	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

WASF2_MOUSE
NC score	0.015155 (rank : 124)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	100	Target Neighborhood Hits	315	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

TACC3_HUMAN
NC score	0.014193 (rank : 125)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	100	Target Neighborhood Hits	779	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

BPA1_MOUSE
NC score	0.010143 (rank : 126)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	100	Target Neighborhood Hits	1477	Shared Neighborhood Hits	25
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

GABPA_HUMAN
NC score	0.009293 (rank : 127)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	100	Target Neighborhood Hits	55	Shared Neighborhood Hits	3
SwissProt Accessions	Q06546, Q12939	Gene names	GABPA, E4TF1A
Domain Architecture
Description	GA-binding protein alpha chain (GABP-subunit alpha) (Transcription factor E4TF1-60) (Nuclear respiratory factor 2 subunit alpha).

DC1I2_HUMAN
NC score	0.009157 (rank : 128)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	100	Target Neighborhood Hits	201	Shared Neighborhood Hits	4
SwissProt Accessions	Q13409, Q96NG7, Q96S87, Q9BXZ5, Q9NT58	Gene names	DYNC1I2, DNCI2, DNCIC2
Domain Architecture
Description	Cytoplasmic dynein 1 intermediate chain 2 (Dynein intermediate chain 2, cytosolic) (DH IC-2) (Cytoplasmic dynein intermediate chain 2).

HXC10_MOUSE
NC score	0.009032 (rank : 129)	θ value	3.0926 (rank : 58)
Query Neighborhood Hits	100	Target Neighborhood Hits	417	Shared Neighborhood Hits	6
SwissProt Accessions	P31257, P31312, Q7TMT7	Gene names	Hoxc10, Hox-3.6, Hoxc-10
Domain Architecture	No domain graphic available
Description	Homeobox protein Hox-C10 (Hox-3.6).

CAC1F_MOUSE
NC score	0.008314 (rank : 130)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	100	Target Neighborhood Hits	142	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

TCF8_HUMAN
NC score	0.005367 (rank : 131)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	100	Target Neighborhood Hits	1057	Shared Neighborhood Hits	19
SwissProt Accessions	P37275, Q12924, Q13800	Gene names	TCF8, AREB6
Domain Architecture
Description	Transcription factor 8 (NIL-2-A zinc finger protein) (Negative regulator of IL2).

PEG3_MOUSE
NC score	0.001760 (rank : 132)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	100	Target Neighborhood Hits	1101	Shared Neighborhood Hits	17
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).