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Network neighborhood for query Sequence : CAPON_HUMAN

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CAPON_HUMAN
SwissProt Accessions	O75052, O43564	Gene names	NOS1AP, CAPON, KIAA0464
Domain Architecture	No domain graphic available
Description	Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C--terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CAPON_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	35	Target Neighborhood Hits	35	Shared Neighborhood Hits	35
SwissProt Accessions	O75052, O43564	Gene names	NOS1AP, CAPON, KIAA0464
Domain Architecture	No domain graphic available
Description	Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C--terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein).

CAPON_MOUSE
θ value	0 (rank : 2)	NC score	0.995727 (rank : 2)
Query Neighborhood Hits	35	Target Neighborhood Hits	34	Shared Neighborhood Hits	28
SwissProt Accessions	Q9D3A8, Q80TZ6	Gene names	Nos1ap, Capon, Kiaa0464
Domain Architecture	No domain graphic available
Description	Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C--terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein).

ARH_HUMAN
θ value	4.16044e-13 (rank : 3)	NC score	0.536488 (rank : 3)
Query Neighborhood Hits	35	Target Neighborhood Hits	38	Shared Neighborhood Hits	19
SwissProt Accessions	Q5SW96, Q6TQS9, Q8N2Y0, Q9UFI9	Gene names	LDLRAP1, ARH
Domain Architecture	No domain graphic available
Description	Low density lipoprotein receptor adapter protein 1 (Autosomal recessive hypercholesterolemia protein).

ANKS1_HUMAN
θ value	4.0297e-08 (rank : 4)	NC score	0.160642 (rank : 12)
Query Neighborhood Hits	35	Target Neighborhood Hits	438	Shared Neighborhood Hits	15
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

ARH_MOUSE
θ value	6.87365e-08 (rank : 5)	NC score	0.503621 (rank : 4)
Query Neighborhood Hits	35	Target Neighborhood Hits	32	Shared Neighborhood Hits	18
SwissProt Accessions	Q8C142, Q6NWV6, Q8VDQ0	Gene names	Ldlrap1, Arh
Domain Architecture	No domain graphic available
Description	Low density lipoprotein receptor adapter protein 1 (Autosomal recessive hypercholesterolemia protein homolog).

ANKS1_MOUSE
θ value	9.92553e-07 (rank : 6)	NC score	0.166153 (rank : 11)
Query Neighborhood Hits	35	Target Neighborhood Hits	453	Shared Neighborhood Hits	15
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

NUMBL_HUMAN
θ value	3.19293e-05 (rank : 7)	NC score	0.316754 (rank : 8)
Query Neighborhood Hits	35	Target Neighborhood Hits	394	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

NUMBL_MOUSE
θ value	3.19293e-05 (rank : 8)	NC score	0.358146 (rank : 5)
Query Neighborhood Hits	35	Target Neighborhood Hits	147	Shared Neighborhood Hits	14
SwissProt Accessions	O08919, Q6NVG8	Gene names	Numbl, Nbl
Domain Architecture
Description	Numb-like protein.

NUMB_HUMAN
θ value	0.000121331 (rank : 9)	NC score	0.351611 (rank : 7)
Query Neighborhood Hits	35	Target Neighborhood Hits	112	Shared Neighborhood Hits	18
SwissProt Accessions	P49757, Q6NUQ7, Q86SY1, Q8WW73, Q9UBG1, Q9UEQ4, Q9UKE8, Q9UKE9, Q9UKF0, Q9UQJ4	Gene names	NUMB
Domain Architecture
Description	Protein numb homolog (h-Numb) (Protein S171).

NUMB_MOUSE
θ value	0.000121331 (rank : 10)	NC score	0.355211 (rank : 6)
Query Neighborhood Hits	35	Target Neighborhood Hits	91	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QZS3, P70422, Q8CIB1, Q9DC57, Q9QZR1, Q9QZS4	Gene names	Numb
Domain Architecture
Description	Protein numb homolog (m-Numb) (m-Nb).

JIP1_MOUSE
θ value	0.00102713 (rank : 11)	NC score	0.216504 (rank : 9)
Query Neighborhood Hits	35	Target Neighborhood Hits	259	Shared Neighborhood Hits	16
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

JIP1_HUMAN
θ value	0.00390308 (rank : 12)	NC score	0.214949 (rank : 10)
Query Neighborhood Hits	35	Target Neighborhood Hits	271	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

APBB2_MOUSE
θ value	0.279714 (rank : 13)	NC score	0.112257 (rank : 13)
Query Neighborhood Hits	35	Target Neighborhood Hits	88	Shared Neighborhood Hits	14
SwissProt Accessions	Q9DBR4, Q6DFX8	Gene names	Apbb2
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2.

TBCD1_MOUSE
θ value	0.279714 (rank : 14)	NC score	0.087878 (rank : 19)
Query Neighborhood Hits	35	Target Neighborhood Hits	241	Shared Neighborhood Hits	14
SwissProt Accessions	Q60949, Q80TJ9, Q923F8	Gene names	Tbc1d1, Kiaa1108, Tbc1
Domain Architecture
Description	TBC1 domain family member 1.

APBB1_HUMAN
θ value	0.62314 (rank : 15)	NC score	0.093797 (rank : 17)
Query Neighborhood Hits	35	Target Neighborhood Hits	62	Shared Neighborhood Hits	12
SwissProt Accessions	O00213, Q96A93	Gene names	APBB1, FE65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

SUHW4_MOUSE
θ value	1.06291 (rank : 16)	NC score	0.010049 (rank : 42)
Query Neighborhood Hits	35	Target Neighborhood Hits	737	Shared Neighborhood Hits	2
SwissProt Accessions	Q68FE8, Q3T9B1, Q8BI82	Gene names	Suhw4
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

APBB1_MOUSE
θ value	1.38821 (rank : 17)	NC score	0.089246 (rank : 18)
Query Neighborhood Hits	35	Target Neighborhood Hits	75	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QXJ1, O08642, Q3TPU0, Q8BNF4, Q8BSR9	Gene names	Apbb1, Fe65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

MYH10_HUMAN
θ value	1.38821 (rank : 18)	NC score	0.014823 (rank : 36)
Query Neighborhood Hits	35	Target Neighborhood Hits	1620	Shared Neighborhood Hits	14
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

APBB2_HUMAN
θ value	1.81305 (rank : 19)	NC score	0.105413 (rank : 14)
Query Neighborhood Hits	35	Target Neighborhood Hits	96	Shared Neighborhood Hits	14
SwissProt Accessions	Q92870, Q8IUI6	Gene names	APBB2, FE65L, FE65L1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2 (Fe65-like protein).

RX_HUMAN
θ value	1.81305 (rank : 20)	NC score	0.009069 (rank : 43)
Query Neighborhood Hits	35	Target Neighborhood Hits	423	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2V3	Gene names	RAX, RX
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

TBCD4_HUMAN
θ value	1.81305 (rank : 21)	NC score	0.072030 (rank : 26)
Query Neighborhood Hits	35	Target Neighborhood Hits	357	Shared Neighborhood Hits	15
SwissProt Accessions	O60343, Q5W0B9	Gene names	TBC1D4, KIAA0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

GOGA4_MOUSE
θ value	2.36792 (rank : 22)	NC score	0.015454 (rank : 35)
Query Neighborhood Hits	35	Target Neighborhood Hits	1939	Shared Neighborhood Hits	16
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

MYH10_MOUSE
θ value	2.36792 (rank : 23)	NC score	0.013840 (rank : 39)
Query Neighborhood Hits	35	Target Neighborhood Hits	1612	Shared Neighborhood Hits	14
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

NOL6_HUMAN
θ value	2.36792 (rank : 24)	NC score	0.037920 (rank : 30)
Query Neighborhood Hits	35	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H6R4, Q5T5M3, Q5T5M4, Q7L4G6, Q8N6I0, Q8TEY9, Q8TEZ0, Q8TEZ1, Q9H675	Gene names	NOL6
Domain Architecture	No domain graphic available
Description	Nucleolar protein 6 (Nucleolar RNA-associated protein) (Nrap).

FGD5_MOUSE
θ value	4.03905 (rank : 25)	NC score	0.018222 (rank : 34)
Query Neighborhood Hits	35	Target Neighborhood Hits	170	Shared Neighborhood Hits	3
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

GOGB1_HUMAN
θ value	4.03905 (rank : 26)	NC score	0.011595 (rank : 41)
Query Neighborhood Hits	35	Target Neighborhood Hits	2297	Shared Neighborhood Hits	15
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

PSIP1_MOUSE
θ value	4.03905 (rank : 27)	NC score	0.019474 (rank : 33)
Query Neighborhood Hits	35	Target Neighborhood Hits	313	Shared Neighborhood Hits	6
SwissProt Accessions	Q99JF8, Q3TEJ7, Q3TTD7, Q3UTA1, Q80WQ7, Q99JF7, Q99LR4, Q9CT03	Gene names	Psip1, Ledgf
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (mLEDGF).

BPAEA_HUMAN
θ value	5.27518 (rank : 28)	NC score	0.013183 (rank : 40)
Query Neighborhood Hits	35	Target Neighborhood Hits	1369	Shared Neighborhood Hits	13
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

DUS2L_HUMAN
θ value	5.27518 (rank : 29)	NC score	0.030829 (rank : 31)
Query Neighborhood Hits	35	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NX74, Q4H4D9	Gene names	DUS2L, DUS2
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 2-like (EC 1.-.-.-) (hDUS2) (Up-regulated in lung cancer) (URLC8).

TBCD4_MOUSE
θ value	5.27518 (rank : 30)	NC score	0.068386 (rank : 27)
Query Neighborhood Hits	35	Target Neighborhood Hits	276	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BYJ6, Q5DU23, Q66JU2, Q6P2M2, Q8BMH6, Q8BXM2	Gene names	Tbc1d4, Kiaa0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

DOT1L_HUMAN
θ value	6.88961 (rank : 31)	NC score	0.019843 (rank : 32)
Query Neighborhood Hits	35	Target Neighborhood Hits	660	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

WWC3_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.038543 (rank : 29)
Query Neighborhood Hits	35	Target Neighborhood Hits	193	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ULE0, Q659C1, Q9BTQ1	Gene names	WWC3, KIAA1280
Domain Architecture	No domain graphic available
Description	WWC family member 3.

GOGA5_MOUSE
θ value	8.99809 (rank : 33)	NC score	0.007478 (rank : 44)
Query Neighborhood Hits	35	Target Neighborhood Hits	1434	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

RIMB1_MOUSE
θ value	8.99809 (rank : 34)	NC score	0.013904 (rank : 38)
Query Neighborhood Hits	35	Target Neighborhood Hits	1376	Shared Neighborhood Hits	15
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SYNE1_HUMAN
θ value	8.99809 (rank : 35)	NC score	0.014555 (rank : 37)
Query Neighborhood Hits	35	Target Neighborhood Hits	1484	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

DAB1_HUMAN
θ value	θ > 10 (rank : 36)	NC score	0.099024 (rank : 16)
Query Neighborhood Hits	35	Target Neighborhood Hits	219	Shared Neighborhood Hits	10
SwissProt Accessions	O75553, Q9NYA8	Gene names	DAB1
Domain Architecture
Description	Disabled homolog 1.

DAB1_MOUSE
θ value	θ > 10 (rank : 37)	NC score	0.102826 (rank : 15)
Query Neighborhood Hits	35	Target Neighborhood Hits	145	Shared Neighborhood Hits	10
SwissProt Accessions	P97318, P97316, P97317	Gene names	Dab1
Domain Architecture
Description	Disabled homolog 1.

DAB2_HUMAN
θ value	θ > 10 (rank : 38)	NC score	0.082787 (rank : 20)
Query Neighborhood Hits	35	Target Neighborhood Hits	197	Shared Neighborhood Hits	11
SwissProt Accessions	P98082, Q13598, Q9BTY0, Q9UK04	Gene names	DAB2, DOC2
Domain Architecture
Description	Disabled homolog 2 (Differentially expressed protein 2) (DOC-2).

DAB2_MOUSE
θ value	θ > 10 (rank : 39)	NC score	0.079221 (rank : 21)
Query Neighborhood Hits	35	Target Neighborhood Hits	163	Shared Neighborhood Hits	9
SwissProt Accessions	P98078, Q3U3K1, Q91W56, Q923E1	Gene names	Dab2, Doc2
Domain Architecture
Description	Disabled homolog 2 (DOC-2) (Mitogen-responsive phosphoprotein).

FA43A_HUMAN
θ value	θ > 10 (rank : 40)	NC score	0.073598 (rank : 24)
Query Neighborhood Hits	35	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N2R8, Q8IXP4, Q8WZ07	Gene names	FAM43A
Domain Architecture	No domain graphic available
Description	Protein FAM43A.

FA43A_MOUSE
θ value	θ > 10 (rank : 41)	NC score	0.073542 (rank : 25)
Query Neighborhood Hits	35	Target Neighborhood Hits	18	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BUP8, Q8R231	Gene names	Fam43a
Domain Architecture	No domain graphic available
Description	Protein FAM43A.

JIP2_HUMAN
θ value	θ > 10 (rank : 42)	NC score	0.075888 (rank : 23)
Query Neighborhood Hits	35	Target Neighborhood Hits	288	Shared Neighborhood Hits	7
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

JIP2_MOUSE
θ value	θ > 10 (rank : 43)	NC score	0.076981 (rank : 22)
Query Neighborhood Hits	35	Target Neighborhood Hits	144	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ERE9, Q9CXI4	Gene names	Mapk8ip2, Ib2, Jip2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

TBCD1_HUMAN
θ value	θ > 10 (rank : 44)	NC score	0.059329 (rank : 28)
Query Neighborhood Hits	35	Target Neighborhood Hits	276	Shared Neighborhood Hits	12
SwissProt Accessions	Q86TI0, Q96K82, Q9UPP4	Gene names	TBC1D1, KIAA1108
Domain Architecture
Description	TBC1 domain family member 1.

Hits sorted by NC score

CAPON_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	35	Target Neighborhood Hits	35	Shared Neighborhood Hits	35
SwissProt Accessions	O75052, O43564	Gene names	NOS1AP, CAPON, KIAA0464
Domain Architecture	No domain graphic available
Description	Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C--terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein).

CAPON_MOUSE
NC score	0.995727 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	35	Target Neighborhood Hits	34	Shared Neighborhood Hits	28
SwissProt Accessions	Q9D3A8, Q80TZ6	Gene names	Nos1ap, Capon, Kiaa0464
Domain Architecture	No domain graphic available
Description	Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C--terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein).

ARH_HUMAN
NC score	0.536488 (rank : 3)	θ value	4.16044e-13 (rank : 3)
Query Neighborhood Hits	35	Target Neighborhood Hits	38	Shared Neighborhood Hits	19
SwissProt Accessions	Q5SW96, Q6TQS9, Q8N2Y0, Q9UFI9	Gene names	LDLRAP1, ARH
Domain Architecture	No domain graphic available
Description	Low density lipoprotein receptor adapter protein 1 (Autosomal recessive hypercholesterolemia protein).

ARH_MOUSE
NC score	0.503621 (rank : 4)	θ value	6.87365e-08 (rank : 5)
Query Neighborhood Hits	35	Target Neighborhood Hits	32	Shared Neighborhood Hits	18
SwissProt Accessions	Q8C142, Q6NWV6, Q8VDQ0	Gene names	Ldlrap1, Arh
Domain Architecture	No domain graphic available
Description	Low density lipoprotein receptor adapter protein 1 (Autosomal recessive hypercholesterolemia protein homolog).

NUMBL_MOUSE
NC score	0.358146 (rank : 5)	θ value	3.19293e-05 (rank : 8)
Query Neighborhood Hits	35	Target Neighborhood Hits	147	Shared Neighborhood Hits	14
SwissProt Accessions	O08919, Q6NVG8	Gene names	Numbl, Nbl
Domain Architecture
Description	Numb-like protein.

NUMB_MOUSE
NC score	0.355211 (rank : 6)	θ value	0.000121331 (rank : 10)
Query Neighborhood Hits	35	Target Neighborhood Hits	91	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QZS3, P70422, Q8CIB1, Q9DC57, Q9QZR1, Q9QZS4	Gene names	Numb
Domain Architecture
Description	Protein numb homolog (m-Numb) (m-Nb).

NUMB_HUMAN
NC score	0.351611 (rank : 7)	θ value	0.000121331 (rank : 9)
Query Neighborhood Hits	35	Target Neighborhood Hits	112	Shared Neighborhood Hits	18
SwissProt Accessions	P49757, Q6NUQ7, Q86SY1, Q8WW73, Q9UBG1, Q9UEQ4, Q9UKE8, Q9UKE9, Q9UKF0, Q9UQJ4	Gene names	NUMB
Domain Architecture
Description	Protein numb homolog (h-Numb) (Protein S171).

NUMBL_HUMAN
NC score	0.316754 (rank : 8)	θ value	3.19293e-05 (rank : 7)
Query Neighborhood Hits	35	Target Neighborhood Hits	394	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

JIP1_MOUSE
NC score	0.216504 (rank : 9)	θ value	0.00102713 (rank : 11)
Query Neighborhood Hits	35	Target Neighborhood Hits	259	Shared Neighborhood Hits	16
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

JIP1_HUMAN
NC score	0.214949 (rank : 10)	θ value	0.00390308 (rank : 12)
Query Neighborhood Hits	35	Target Neighborhood Hits	271	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

ANKS1_MOUSE
NC score	0.166153 (rank : 11)	θ value	9.92553e-07 (rank : 6)
Query Neighborhood Hits	35	Target Neighborhood Hits	453	Shared Neighborhood Hits	15
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

ANKS1_HUMAN
NC score	0.160642 (rank : 12)	θ value	4.0297e-08 (rank : 4)
Query Neighborhood Hits	35	Target Neighborhood Hits	438	Shared Neighborhood Hits	15
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

APBB2_MOUSE
NC score	0.112257 (rank : 13)	θ value	0.279714 (rank : 13)
Query Neighborhood Hits	35	Target Neighborhood Hits	88	Shared Neighborhood Hits	14
SwissProt Accessions	Q9DBR4, Q6DFX8	Gene names	Apbb2
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2.

APBB2_HUMAN
NC score	0.105413 (rank : 14)	θ value	1.81305 (rank : 19)
Query Neighborhood Hits	35	Target Neighborhood Hits	96	Shared Neighborhood Hits	14
SwissProt Accessions	Q92870, Q8IUI6	Gene names	APBB2, FE65L, FE65L1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2 (Fe65-like protein).

DAB1_MOUSE
NC score	0.102826 (rank : 15)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	35	Target Neighborhood Hits	145	Shared Neighborhood Hits	10
SwissProt Accessions	P97318, P97316, P97317	Gene names	Dab1
Domain Architecture
Description	Disabled homolog 1.

DAB1_HUMAN
NC score	0.099024 (rank : 16)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	35	Target Neighborhood Hits	219	Shared Neighborhood Hits	10
SwissProt Accessions	O75553, Q9NYA8	Gene names	DAB1
Domain Architecture
Description	Disabled homolog 1.

APBB1_HUMAN
NC score	0.093797 (rank : 17)	θ value	0.62314 (rank : 15)
Query Neighborhood Hits	35	Target Neighborhood Hits	62	Shared Neighborhood Hits	12
SwissProt Accessions	O00213, Q96A93	Gene names	APBB1, FE65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

APBB1_MOUSE
NC score	0.089246 (rank : 18)	θ value	1.38821 (rank : 17)
Query Neighborhood Hits	35	Target Neighborhood Hits	75	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QXJ1, O08642, Q3TPU0, Q8BNF4, Q8BSR9	Gene names	Apbb1, Fe65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

TBCD1_MOUSE
NC score	0.087878 (rank : 19)	θ value	0.279714 (rank : 14)
Query Neighborhood Hits	35	Target Neighborhood Hits	241	Shared Neighborhood Hits	14
SwissProt Accessions	Q60949, Q80TJ9, Q923F8	Gene names	Tbc1d1, Kiaa1108, Tbc1
Domain Architecture
Description	TBC1 domain family member 1.

DAB2_HUMAN
NC score	0.082787 (rank : 20)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	35	Target Neighborhood Hits	197	Shared Neighborhood Hits	11
SwissProt Accessions	P98082, Q13598, Q9BTY0, Q9UK04	Gene names	DAB2, DOC2
Domain Architecture
Description	Disabled homolog 2 (Differentially expressed protein 2) (DOC-2).

DAB2_MOUSE
NC score	0.079221 (rank : 21)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	35	Target Neighborhood Hits	163	Shared Neighborhood Hits	9
SwissProt Accessions	P98078, Q3U3K1, Q91W56, Q923E1	Gene names	Dab2, Doc2
Domain Architecture
Description	Disabled homolog 2 (DOC-2) (Mitogen-responsive phosphoprotein).

JIP2_MOUSE
NC score	0.076981 (rank : 22)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	35	Target Neighborhood Hits	144	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ERE9, Q9CXI4	Gene names	Mapk8ip2, Ib2, Jip2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

JIP2_HUMAN
NC score	0.075888 (rank : 23)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	35	Target Neighborhood Hits	288	Shared Neighborhood Hits	7
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

FA43A_HUMAN
NC score	0.073598 (rank : 24)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	35	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N2R8, Q8IXP4, Q8WZ07	Gene names	FAM43A
Domain Architecture	No domain graphic available
Description	Protein FAM43A.

FA43A_MOUSE
NC score	0.073542 (rank : 25)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	35	Target Neighborhood Hits	18	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BUP8, Q8R231	Gene names	Fam43a
Domain Architecture	No domain graphic available
Description	Protein FAM43A.

TBCD4_HUMAN
NC score	0.072030 (rank : 26)	θ value	1.81305 (rank : 21)
Query Neighborhood Hits	35	Target Neighborhood Hits	357	Shared Neighborhood Hits	15
SwissProt Accessions	O60343, Q5W0B9	Gene names	TBC1D4, KIAA0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

TBCD4_MOUSE
NC score	0.068386 (rank : 27)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	35	Target Neighborhood Hits	276	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BYJ6, Q5DU23, Q66JU2, Q6P2M2, Q8BMH6, Q8BXM2	Gene names	Tbc1d4, Kiaa0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

TBCD1_HUMAN
NC score	0.059329 (rank : 28)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	35	Target Neighborhood Hits	276	Shared Neighborhood Hits	12
SwissProt Accessions	Q86TI0, Q96K82, Q9UPP4	Gene names	TBC1D1, KIAA1108
Domain Architecture
Description	TBC1 domain family member 1.

WWC3_HUMAN
NC score	0.038543 (rank : 29)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	35	Target Neighborhood Hits	193	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ULE0, Q659C1, Q9BTQ1	Gene names	WWC3, KIAA1280
Domain Architecture	No domain graphic available
Description	WWC family member 3.

NOL6_HUMAN
NC score	0.037920 (rank : 30)	θ value	2.36792 (rank : 24)
Query Neighborhood Hits	35	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H6R4, Q5T5M3, Q5T5M4, Q7L4G6, Q8N6I0, Q8TEY9, Q8TEZ0, Q8TEZ1, Q9H675	Gene names	NOL6
Domain Architecture	No domain graphic available
Description	Nucleolar protein 6 (Nucleolar RNA-associated protein) (Nrap).

DUS2L_HUMAN
NC score	0.030829 (rank : 31)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	35	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NX74, Q4H4D9	Gene names	DUS2L, DUS2
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 2-like (EC 1.-.-.-) (hDUS2) (Up-regulated in lung cancer) (URLC8).

DOT1L_HUMAN
NC score	0.019843 (rank : 32)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	35	Target Neighborhood Hits	660	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

PSIP1_MOUSE
NC score	0.019474 (rank : 33)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	35	Target Neighborhood Hits	313	Shared Neighborhood Hits	6
SwissProt Accessions	Q99JF8, Q3TEJ7, Q3TTD7, Q3UTA1, Q80WQ7, Q99JF7, Q99LR4, Q9CT03	Gene names	Psip1, Ledgf
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (mLEDGF).

FGD5_MOUSE
NC score	0.018222 (rank : 34)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	35	Target Neighborhood Hits	170	Shared Neighborhood Hits	3
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

GOGA4_MOUSE
NC score	0.015454 (rank : 35)	θ value	2.36792 (rank : 22)
Query Neighborhood Hits	35	Target Neighborhood Hits	1939	Shared Neighborhood Hits	16
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

MYH10_HUMAN
NC score	0.014823 (rank : 36)	θ value	1.38821 (rank : 18)
Query Neighborhood Hits	35	Target Neighborhood Hits	1620	Shared Neighborhood Hits	14
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

SYNE1_HUMAN
NC score	0.014555 (rank : 37)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	35	Target Neighborhood Hits	1484	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

RIMB1_MOUSE
NC score	0.013904 (rank : 38)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	35	Target Neighborhood Hits	1376	Shared Neighborhood Hits	15
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

MYH10_MOUSE
NC score	0.013840 (rank : 39)	θ value	2.36792 (rank : 23)
Query Neighborhood Hits	35	Target Neighborhood Hits	1612	Shared Neighborhood Hits	14
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

BPAEA_HUMAN
NC score	0.013183 (rank : 40)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	35	Target Neighborhood Hits	1369	Shared Neighborhood Hits	13
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

GOGB1_HUMAN
NC score	0.011595 (rank : 41)	θ value	4.03905 (rank : 26)
Query Neighborhood Hits	35	Target Neighborhood Hits	2297	Shared Neighborhood Hits	15
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

SUHW4_MOUSE
NC score	0.010049 (rank : 42)	θ value	1.06291 (rank : 16)
Query Neighborhood Hits	35	Target Neighborhood Hits	737	Shared Neighborhood Hits	2
SwissProt Accessions	Q68FE8, Q3T9B1, Q8BI82	Gene names	Suhw4
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

RX_HUMAN
NC score	0.009069 (rank : 43)	θ value	1.81305 (rank : 20)
Query Neighborhood Hits	35	Target Neighborhood Hits	423	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2V3	Gene names	RAX, RX
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

GOGA5_MOUSE
NC score	0.007478 (rank : 44)	θ value	8.99809 (rank : 33)
Query Neighborhood Hits	35	Target Neighborhood Hits	1434	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).