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Network neighborhood for query Sequence : P3C2G_HUMAN

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P3C2G_HUMAN
SwissProt Accessions	O75747	Gene names	PIK3C2G
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

P3C2A_HUMAN
θ value	0 (rank : 1)	NC score	0.904715 (rank : 8)
Query Neighborhood Hits	92	Target Neighborhood Hits	188	Shared Neighborhood Hits	70
SwissProt Accessions	O00443	Gene names	PIK3C2A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha).

P3C2A_MOUSE
θ value	0 (rank : 2)	NC score	0.906437 (rank : 7)
Query Neighborhood Hits	92	Target Neighborhood Hits	181	Shared Neighborhood Hits	70
SwissProt Accessions	Q61194, Q61182	Gene names	Pik3c2a, Cpk
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).

P3C2B_HUMAN
θ value	0 (rank : 3)	NC score	0.887741 (rank : 13)
Query Neighborhood Hits	92	Target Neighborhood Hits	148	Shared Neighborhood Hits	70
SwissProt Accessions	O00750, O95666, Q5SW99	Gene names	PIK3C2B
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-beta) (PtdIns-3-kinase C2 beta) (PI3K-C2beta) (C2-PI3K).

P3C2G_HUMAN
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	92	Target Neighborhood Hits	92	Shared Neighborhood Hits	92
SwissProt Accessions	O75747	Gene names	PIK3C2G
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).

P3C2G_MOUSE
θ value	0 (rank : 5)	NC score	0.993700 (rank : 2)
Query Neighborhood Hits	92	Target Neighborhood Hits	113	Shared Neighborhood Hits	73
SwissProt Accessions	O70167, O70168	Gene names	Pik3c2g
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).

PK3CG_HUMAN
θ value	9.69798e-87 (rank : 6)	NC score	0.913030 (rank : 3)
Query Neighborhood Hits	92	Target Neighborhood Hits	41	Shared Neighborhood Hits	28
SwissProt Accessions	P48736, Q8IV23, Q9BZC8	Gene names	PIK3CG
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

PK3CA_MOUSE
θ value	1.82896e-85 (rank : 7)	NC score	0.908405 (rank : 5)
Query Neighborhood Hits	92	Target Neighborhood Hits	48	Shared Neighborhood Hits	28
SwissProt Accessions	P42337	Gene names	Pik3ca
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).

PK3CG_MOUSE
θ value	5.32145e-85 (rank : 8)	NC score	0.911651 (rank : 4)
Query Neighborhood Hits	92	Target Neighborhood Hits	43	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JHG7	Gene names	Pik3cg, Pi3kg1
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

PK3CA_HUMAN
θ value	2.64101e-84 (rank : 9)	NC score	0.908151 (rank : 6)
Query Neighborhood Hits	92	Target Neighborhood Hits	45	Shared Neighborhood Hits	28
SwissProt Accessions	P42336, Q99762	Gene names	PIK3CA
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).

PK3CD_HUMAN
θ value	2.3998e-69 (rank : 10)	NC score	0.894318 (rank : 9)
Query Neighborhood Hits	92	Target Neighborhood Hits	40	Shared Neighborhood Hits	28
SwissProt Accessions	O00329, O15445	Gene names	PIK3CD
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit delta) (PtdIns-3- kinase p110) (PI3K) (p110delta).

PK3CD_MOUSE
θ value	9.11921e-69 (rank : 11)	NC score	0.893737 (rank : 10)
Query Neighborhood Hits	92	Target Neighborhood Hits	42	Shared Neighborhood Hits	28
SwissProt Accessions	O35904	Gene names	Pik3cd
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit delta) (PtdIns-3- kinase p110) (PI3K) (p110delta).

PK3CB_MOUSE
θ value	1.31681e-67 (rank : 12)	NC score	0.890762 (rank : 11)
Query Neighborhood Hits	92	Target Neighborhood Hits	49	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BTI9	Gene names	Pik3cb
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).

PK3CB_HUMAN
θ value	8.53533e-67 (rank : 13)	NC score	0.890416 (rank : 12)
Query Neighborhood Hits	92	Target Neighborhood Hits	43	Shared Neighborhood Hits	28
SwissProt Accessions	P42338	Gene names	PIK3CB
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).

PK3C3_HUMAN
θ value	4.2656e-42 (rank : 14)	NC score	0.844506 (rank : 14)
Query Neighborhood Hits	92	Target Neighborhood Hits	49	Shared Neighborhood Hits	28
SwissProt Accessions	Q8NEB9, Q15134	Gene names	PIK3C3
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC 2.7.1.137) (PtdIns-3-kinase type 3) (PI3-kinase type 3) (PI3K type 3) (Phosphoinositide-3-kinase class 3) (Phosphatidylinositol 3-kinase p100 subunit).

PK3C3_MOUSE
θ value	3.61106e-41 (rank : 15)	NC score	0.842887 (rank : 15)
Query Neighborhood Hits	92	Target Neighborhood Hits	49	Shared Neighborhood Hits	28
SwissProt Accessions	Q6PF93, Q8R3S8	Gene names	Pik3c3
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC 2.7.1.137) (PtdIns-3-kinase type 3) (PI3-kinase type 3) (PI3K type 3) (Phosphoinositide-3-kinase class 3).

PI4KA_HUMAN
θ value	7.54701e-31 (rank : 16)	NC score	0.809030 (rank : 16)
Query Neighborhood Hits	92	Target Neighborhood Hits	53	Shared Neighborhood Hits	28
SwissProt Accessions	P42356, Q7Z625, Q9UPG2	Gene names	PIK4CA, PIK4
Domain Architecture
Description	Phosphatidylinositol 4-kinase alpha (EC 2.7.1.67) (PI4-kinase alpha) (PtdIns-4-kinase alpha) (PI4K-alpha).

PI4KB_MOUSE
θ value	4.01107e-24 (rank : 17)	NC score	0.764934 (rank : 17)
Query Neighborhood Hits	92	Target Neighborhood Hits	67	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BKC8, Q8C146	Gene names	Pik4cb
Domain Architecture
Description	Phosphatidylinositol 4-kinase beta (EC 2.7.1.67) (PtdIns 4-kinase beta) (PI4Kbeta) (PI4K-beta).

PI4KB_HUMAN
θ value	1.5242e-23 (rank : 18)	NC score	0.762984 (rank : 18)
Query Neighborhood Hits	92	Target Neighborhood Hits	79	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UBF8, O15096, P78405, Q9BWR6	Gene names	PIK4CB, PI4KB
Domain Architecture
Description	Phosphatidylinositol 4-kinase beta (EC 2.7.1.67) (PtdIns 4-kinase beta) (PI4Kbeta) (PI4K-beta) (NPIK) (PI4K92).

FRAP_MOUSE
θ value	1.17247e-07 (rank : 19)	NC score	0.390587 (rank : 19)
Query Neighborhood Hits	92	Target Neighborhood Hits	77	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JLN9, Q811J5, Q9CST1	Gene names	Frap1, Frap
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

FRAP_HUMAN
θ value	1.99992e-07 (rank : 20)	NC score	0.389478 (rank : 20)
Query Neighborhood Hits	92	Target Neighborhood Hits	83	Shared Neighborhood Hits	28
SwissProt Accessions	P42345, Q6LE87, Q96QG3, Q9Y4I3	Gene names	FRAP1, FRAP, FRAP2
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

RIMS1_HUMAN
θ value	4.1701e-05 (rank : 21)	NC score	0.219602 (rank : 31)
Query Neighborhood Hits	92	Target Neighborhood Hits	437	Shared Neighborhood Hits	47
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

PRKDC_MOUSE
θ value	0.000158464 (rank : 22)	NC score	0.344490 (rank : 21)
Query Neighborhood Hits	92	Target Neighborhood Hits	92	Shared Neighborhood Hits	30
SwissProt Accessions	P97313, O88187, P97928, Q307W9, Q3V2W8, Q8C2A7, Q9Z341	Gene names	Prkdc, Xrcc7
Domain Architecture
Description	DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (P460).

RIMS2_HUMAN
θ value	0.000158464 (rank : 23)	NC score	0.205780 (rank : 33)
Query Neighborhood Hits	92	Target Neighborhood Hits	342	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
θ value	0.000158464 (rank : 24)	NC score	0.204938 (rank : 34)
Query Neighborhood Hits	92	Target Neighborhood Hits	376	Shared Neighborhood Hits	48
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

ATM_HUMAN
θ value	0.00020696 (rank : 25)	NC score	0.307354 (rank : 25)
Query Neighborhood Hits	92	Target Neighborhood Hits	78	Shared Neighborhood Hits	28
SwissProt Accessions	Q13315, O15429, Q12758, Q16551, Q93007, Q9NP02, Q9UCX7	Gene names	ATM
Domain Architecture
Description	Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated) (A-T, mutated).

ATR_MOUSE
θ value	0.00020696 (rank : 26)	NC score	0.318408 (rank : 23)
Query Neighborhood Hits	92	Target Neighborhood Hits	63	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JKK8	Gene names	Atr
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein).

ATM_MOUSE
θ value	0.000270298 (rank : 27)	NC score	0.298416 (rank : 26)
Query Neighborhood Hits	92	Target Neighborhood Hits	93	Shared Neighborhood Hits	28
SwissProt Accessions	Q62388	Gene names	Atm
Domain Architecture
Description	Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated homolog) (A-T, mutated homolog).

SNX27_HUMAN
θ value	0.000270298 (rank : 28)	NC score	0.080898 (rank : 81)
Query Neighborhood Hits	92	Target Neighborhood Hits	54	Shared Neighborhood Hits	7
SwissProt Accessions	Q96L92	Gene names	SNX27
Domain Architecture
Description	Sorting nexin-27.

ATR_HUMAN
θ value	0.000602161 (rank : 29)	NC score	0.316835 (rank : 24)
Query Neighborhood Hits	92	Target Neighborhood Hits	71	Shared Neighborhood Hits	28
SwissProt Accessions	Q13535, Q7KYL3, Q93051, Q9BXK4	Gene names	ATR, FRP1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein) (FRAP-related protein 1).

SYTL2_HUMAN
θ value	0.000602161 (rank : 30)	NC score	0.180253 (rank : 41)
Query Neighborhood Hits	92	Target Neighborhood Hits	248	Shared Neighborhood Hits	47
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

PCLO_HUMAN
θ value	0.000786445 (rank : 31)	NC score	0.144077 (rank : 47)
Query Neighborhood Hits	92	Target Neighborhood Hits	2046	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PCLO_MOUSE
θ value	0.00175202 (rank : 32)	NC score	0.133346 (rank : 52)
Query Neighborhood Hits	92	Target Neighborhood Hits	2275	Shared Neighborhood Hits	52
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PRKDC_HUMAN
θ value	0.00175202 (rank : 33)	NC score	0.333730 (rank : 22)
Query Neighborhood Hits	92	Target Neighborhood Hits	93	Shared Neighborhood Hits	28
SwissProt Accessions	P78527, P78528, Q13327, Q13337, Q14175, Q59H99, Q7Z611, Q96SE6, Q9UME3	Gene names	PRKDC
Domain Architecture
Description	DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (DNPK1) (p460).

SYTL2_MOUSE
θ value	0.00298849 (rank : 34)	NC score	0.177692 (rank : 42)
Query Neighborhood Hits	92	Target Neighborhood Hits	253	Shared Neighborhood Hits	45
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

RIMS3_MOUSE
θ value	0.00665767 (rank : 35)	NC score	0.200437 (rank : 36)
Query Neighborhood Hits	92	Target Neighborhood Hits	67	Shared Neighborhood Hits	45
SwissProt Accessions	Q80U57	Gene names	Rims3, Kiaa0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

SYTL3_MOUSE
θ value	0.00665767 (rank : 36)	NC score	0.207243 (rank : 32)
Query Neighborhood Hits	92	Target Neighborhood Hits	110	Shared Neighborhood Hits	47
SwissProt Accessions	Q99N48, Q8C506, Q99N47, Q99N49, Q99N54, Q99N79	Gene names	Sytl3, Slp3
Domain Architecture
Description	Synaptotagmin-like protein 3 (Exophilin-6).

RIMS3_HUMAN
θ value	0.00869519 (rank : 37)	NC score	0.201492 (rank : 35)
Query Neighborhood Hits	92	Target Neighborhood Hits	66	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UJD0, Q92511	Gene names	RIMS3, KIAA0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

RIMS4_HUMAN
θ value	0.00869519 (rank : 38)	NC score	0.245314 (rank : 28)
Query Neighborhood Hits	92	Target Neighborhood Hits	76	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H426, Q5JWT7	Gene names	RIMS4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

RIMS4_MOUSE
θ value	0.00869519 (rank : 39)	NC score	0.245494 (rank : 27)
Query Neighborhood Hits	92	Target Neighborhood Hits	76	Shared Neighborhood Hits	47
SwissProt Accessions	P60191	Gene names	Rims4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

SYTL4_HUMAN
θ value	0.0563607 (rank : 40)	NC score	0.175277 (rank : 44)
Query Neighborhood Hits	92	Target Neighborhood Hits	138	Shared Neighborhood Hits	47
SwissProt Accessions	Q96C24, Q5H9J3, Q5JPG8, Q8N9P4, Q9H4R0, Q9H4R1	Gene names	SYTL4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

SYTL4_MOUSE
θ value	0.0563607 (rank : 41)	NC score	0.174385 (rank : 45)
Query Neighborhood Hits	92	Target Neighborhood Hits	137	Shared Neighborhood Hits	47
SwissProt Accessions	Q9R0Q1, Q8R321, Q9R0Q0	Gene names	Sytl4, Slp4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

SYTL5_HUMAN
θ value	0.0563607 (rank : 42)	NC score	0.181830 (rank : 38)
Query Neighborhood Hits	92	Target Neighborhood Hits	237	Shared Neighborhood Hits	47
SwissProt Accessions	Q8TDW5	Gene names	SYTL5, SLP5
Domain Architecture
Description	Synaptotagmin-like protein 5.

KPCA_HUMAN
θ value	0.0961366 (rank : 43)	NC score	0.039697 (rank : 87)
Query Neighborhood Hits	92	Target Neighborhood Hits	1070	Shared Neighborhood Hits	47
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

SYTL1_HUMAN
θ value	0.0961366 (rank : 44)	NC score	0.181372 (rank : 40)
Query Neighborhood Hits	92	Target Neighborhood Hits	227	Shared Neighborhood Hits	48
SwissProt Accessions	Q8IYJ3, Q96BB6, Q96GU6, Q96S89, Q96SI0	Gene names	SYTL1, SLP1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1) (SB146).

SYTL5_MOUSE
θ value	0.163984 (rank : 45)	NC score	0.181493 (rank : 39)
Query Neighborhood Hits	92	Target Neighborhood Hits	154	Shared Neighborhood Hits	47
SwissProt Accessions	Q80T23, Q812E5	Gene names	Sytl5, Slp5
Domain Architecture
Description	Synaptotagmin-like protein 5.

FA62A_HUMAN
θ value	0.21417 (rank : 46)	NC score	0.177266 (rank : 43)
Query Neighborhood Hits	92	Target Neighborhood Hits	168	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

KPCA_MOUSE
θ value	0.21417 (rank : 47)	NC score	0.037264 (rank : 91)
Query Neighborhood Hits	92	Target Neighborhood Hits	1067	Shared Neighborhood Hits	47
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

SYT11_MOUSE
θ value	0.279714 (rank : 48)	NC score	0.113452 (rank : 68)
Query Neighborhood Hits	92	Target Neighborhood Hits	116	Shared Neighborhood Hits	47
SwissProt Accessions	Q9R0N3	Gene names	Syt11
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

SYT11_HUMAN
θ value	0.365318 (rank : 49)	NC score	0.112581 (rank : 70)
Query Neighborhood Hits	92	Target Neighborhood Hits	113	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BT88, Q14998, Q68CT5, Q8IXU3, Q96SU2	Gene names	SYT11, KIAA0080
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

KPCG_MOUSE
θ value	0.62314 (rank : 50)	NC score	0.038766 (rank : 89)
Query Neighborhood Hits	92	Target Neighborhood Hits	1123	Shared Neighborhood Hits	47
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

RGS3_HUMAN
θ value	0.62314 (rank : 51)	NC score	0.068092 (rank : 82)
Query Neighborhood Hits	92	Target Neighborhood Hits	1375	Shared Neighborhood Hits	48
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SYT15_HUMAN
θ value	0.62314 (rank : 52)	NC score	0.129530 (rank : 56)
Query Neighborhood Hits	92	Target Neighborhood Hits	112	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BQS2, Q7Z439, Q7Z440	Gene names	SYT15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV) (Chr10Syt).

SYT2_HUMAN
θ value	0.62314 (rank : 53)	NC score	0.121752 (rank : 60)
Query Neighborhood Hits	92	Target Neighborhood Hits	142	Shared Neighborhood Hits	47
SwissProt Accessions	Q8N9I0, Q496K5, Q8NBE5	Gene names	SYT2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT2_MOUSE
θ value	0.62314 (rank : 54)	NC score	0.121993 (rank : 59)
Query Neighborhood Hits	92	Target Neighborhood Hits	143	Shared Neighborhood Hits	47
SwissProt Accessions	P46097, Q8R0E1	Gene names	Syt2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

PLD2_MOUSE
θ value	0.813845 (rank : 55)	NC score	0.020148 (rank : 96)
Query Neighborhood Hits	92	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	P97813	Gene names	Pld2
Domain Architecture
Description	Phospholipase D2 (EC 3.1.4.4) (PLD 2) (Choline phosphatase 2) (Phosphatidylcholine-hydrolyzing phospholipase D2) (PLD1C) (mPLD2).

IFT74_HUMAN
θ value	1.06291 (rank : 56)	NC score	0.003611 (rank : 107)
Query Neighborhood Hits	92	Target Neighborhood Hits	949	Shared Neighborhood Hits	7
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

NFRKB_MOUSE
θ value	1.06291 (rank : 57)	NC score	0.018737 (rank : 99)
Query Neighborhood Hits	92	Target Neighborhood Hits	393	Shared Neighborhood Hits	7
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

GON4L_MOUSE
θ value	1.38821 (rank : 58)	NC score	0.014732 (rank : 100)
Query Neighborhood Hits	92	Target Neighborhood Hits	455	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

KPCG_HUMAN
θ value	1.38821 (rank : 59)	NC score	0.037177 (rank : 92)
Query Neighborhood Hits	92	Target Neighborhood Hits	1126	Shared Neighborhood Hits	47
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

SYT5_HUMAN
θ value	1.38821 (rank : 60)	NC score	0.122931 (rank : 58)
Query Neighborhood Hits	92	Target Neighborhood Hits	138	Shared Neighborhood Hits	47
SwissProt Accessions	O00445, Q86X72	Gene names	SYT5
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV).

SYT5_MOUSE
θ value	1.38821 (rank : 61)	NC score	0.114336 (rank : 66)
Query Neighborhood Hits	92	Target Neighborhood Hits	140	Shared Neighborhood Hits	47
SwissProt Accessions	Q9R0N5	Gene names	Syt5, Syt9
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV) (Synaptotagmin IX).

CCHCR_MOUSE
θ value	1.81305 (rank : 62)	NC score	0.003785 (rank : 105)
Query Neighborhood Hits	92	Target Neighborhood Hits	932	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

FA62A_MOUSE
θ value	1.81305 (rank : 63)	NC score	0.187993 (rank : 37)
Query Neighborhood Hits	92	Target Neighborhood Hits	155	Shared Neighborhood Hits	47
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

SMG1_HUMAN
θ value	1.81305 (rank : 64)	NC score	0.234570 (rank : 30)
Query Neighborhood Hits	92	Target Neighborhood Hits	231	Shared Neighborhood Hits	29
SwissProt Accessions	Q96Q15, O43305, Q13284, Q8NFX2, Q96QV0, Q96RW3	Gene names	SMG1, ATX, KIAA0421, LIP
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1) (hSMG-1) (Lambda/iota protein kinase C-interacting protein) (Lambda-interacting protein) (61E3.4).

SMG1_MOUSE
θ value	1.81305 (rank : 65)	NC score	0.236524 (rank : 29)
Query Neighborhood Hits	92	Target Neighborhood Hits	212	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BKX6, Q5DU42, Q6ZQC0, Q8BLU4, Q8BWJ5, Q8BXD3	Gene names	Smg1, Kiaa0421
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1).

DOC2B_HUMAN
θ value	2.36792 (rank : 66)	NC score	0.140429 (rank : 48)
Query Neighborhood Hits	92	Target Neighborhood Hits	150	Shared Neighborhood Hits	47
SwissProt Accessions	Q14184	Gene names	DOC2B
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

ZFY28_HUMAN
θ value	2.36792 (rank : 67)	NC score	0.010965 (rank : 103)
Query Neighborhood Hits	92	Target Neighborhood Hits	152	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HCC9	Gene names	ZFYVE28, KIAA1643
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 28.

SNX17_HUMAN
θ value	3.0926 (rank : 68)	NC score	0.039467 (rank : 88)
Query Neighborhood Hits	92	Target Neighborhood Hits	35	Shared Neighborhood Hits	8
SwissProt Accessions	Q15036, Q53HN7, Q6IAS3	Gene names	SNX17, KIAA0064
Domain Architecture
Description	Sorting nexin-17.

SNX17_MOUSE
θ value	3.0926 (rank : 69)	NC score	0.037920 (rank : 90)
Query Neighborhood Hits	92	Target Neighborhood Hits	34	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BVL3, Q8R0N8	Gene names	Snx17
Domain Architecture	No domain graphic available
Description	Sorting nexin-17.

RP3A_HUMAN
θ value	4.03905 (rank : 70)	NC score	0.137223 (rank : 50)
Query Neighborhood Hits	92	Target Neighborhood Hits	305	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SNX11_HUMAN
θ value	4.03905 (rank : 71)	NC score	0.029663 (rank : 94)
Query Neighborhood Hits	92	Target Neighborhood Hits	47	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y5W9, Q9H885	Gene names	SNX11
Domain Architecture
Description	Sorting nexin-11.

SNX11_MOUSE
θ value	4.03905 (rank : 72)	NC score	0.029461 (rank : 95)
Query Neighborhood Hits	92	Target Neighborhood Hits	51	Shared Neighborhood Hits	7
SwissProt Accessions	Q91WL6, Q3V3A6	Gene names	Snx11
Domain Architecture	No domain graphic available
Description	Sorting nexin-11.

TRIM8_HUMAN
θ value	4.03905 (rank : 73)	NC score	0.002610 (rank : 112)
Query Neighborhood Hits	92	Target Neighborhood Hits	650	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

UGDH_HUMAN
θ value	4.03905 (rank : 74)	NC score	0.018843 (rank : 98)
Query Neighborhood Hits	92	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	O60701, O60589	Gene names	UGDH
Domain Architecture
Description	UDP-glucose 6-dehydrogenase (EC 1.1.1.22) (UDP-Glc dehydrogenase) (UDP-GlcDH) (UDPGDH).

UGDH_MOUSE
θ value	4.03905 (rank : 75)	NC score	0.018852 (rank : 97)
Query Neighborhood Hits	92	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	O70475	Gene names	Ugdh
Domain Architecture
Description	UDP-glucose 6-dehydrogenase (EC 1.1.1.22) (UDP-Glc dehydrogenase) (UDP-GlcDH) (UDPGDH).

CB010_HUMAN
θ value	5.27518 (rank : 76)	NC score	0.013271 (rank : 102)
Query Neighborhood Hits	92	Target Neighborhood Hits	130	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z570, Q6ZN26	Gene names	C2orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf10.

PLD1_HUMAN
θ value	5.27518 (rank : 77)	NC score	0.014457 (rank : 101)
Query Neighborhood Hits	92	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	Q13393	Gene names	PLD1
Domain Architecture
Description	Phospholipase D1 (EC 3.1.4.4) (PLD 1) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1) (hPLD1).

STON1_HUMAN
θ value	5.27518 (rank : 78)	NC score	0.008105 (rank : 104)
Query Neighborhood Hits	92	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y6Q2, Q96JE3, Q9BYX3	Gene names	STON1, SALF, SBLF, STN1
Domain Architecture
Description	Stonin-1 (Stoned B-like factor).

DOC2B_MOUSE
θ value	6.88961 (rank : 79)	NC score	0.137935 (rank : 49)
Query Neighborhood Hits	92	Target Neighborhood Hits	169	Shared Neighborhood Hits	47
SwissProt Accessions	P70169, Q6NXK3	Gene names	Doc2b
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

KPCB_HUMAN
θ value	6.88961 (rank : 80)	NC score	0.034943 (rank : 93)
Query Neighborhood Hits	92	Target Neighborhood Hits	1121	Shared Neighborhood Hits	47
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

RP3A_MOUSE
θ value	6.88961 (rank : 81)	NC score	0.133083 (rank : 53)
Query Neighborhood Hits	92	Target Neighborhood Hits	510	Shared Neighborhood Hits	47
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SEPT4_HUMAN
θ value	6.88961 (rank : 82)	NC score	0.003176 (rank : 110)
Query Neighborhood Hits	92	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	O43236, Q9UM58	Gene names	SEPT4, PNUTL2
Domain Architecture
Description	Septin-4 (Peanut-like protein 2) (Brain protein H5) (Cell division control-related protein 2) (hCDCREL-2) (Bradeion beta) (CE5B3 beta) (Cerebral protein 7).

DHX36_HUMAN
θ value	8.99809 (rank : 83)	NC score	0.002679 (rank : 111)
Query Neighborhood Hits	92	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H2U1, Q70JU3, Q8IYE5, Q9P240	Gene names	DHX36, DDX36, KIAA1488, MLEL1, RHAU
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

DNJA4_HUMAN
θ value	8.99809 (rank : 84)	NC score	0.003264 (rank : 108)
Query Neighborhood Hits	92	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WW22, Q8N7P2	Gene names	DNAJA4
Domain Architecture
Description	DnaJ homolog subfamily A member 4.

DNJA4_MOUSE
θ value	8.99809 (rank : 85)	NC score	0.003242 (rank : 109)
Query Neighborhood Hits	92	Target Neighborhood Hits	87	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JMC3, Q543S9, Q9CTD6, Q9CUD4	Gene names	Dnaja4
Domain Architecture
Description	DnaJ homolog subfamily A member 4 (MmDjA4).

DOC2A_HUMAN
θ value	8.99809 (rank : 86)	NC score	0.134454 (rank : 51)
Query Neighborhood Hits	92	Target Neighborhood Hits	144	Shared Neighborhood Hits	46
SwissProt Accessions	Q14183, Q6P4G4, Q7Z5G0, Q8IVX0	Gene names	DOC2A
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha) (Doc2).

MTA2_HUMAN
θ value	8.99809 (rank : 87)	NC score	0.003713 (rank : 106)
Query Neighborhood Hits	92	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	O94776, Q9UQB5	Gene names	MTA2, MTA1L1, PID
Domain Architecture
Description	Metastasis-associated protein MTA2 (Metastasis-associated 1-like 1) (MTA1-L1 protein) (p53 target protein in deacetylase complex).

SYT10_MOUSE
θ value	8.99809 (rank : 88)	NC score	0.107745 (rank : 76)
Query Neighborhood Hits	92	Target Neighborhood Hits	133	Shared Neighborhood Hits	47
SwissProt Accessions	Q9R0N4	Gene names	Syt10
Domain Architecture
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

SYT1_HUMAN
θ value	8.99809 (rank : 89)	NC score	0.118568 (rank : 63)
Query Neighborhood Hits	92	Target Neighborhood Hits	150	Shared Neighborhood Hits	47
SwissProt Accessions	P21579	Gene names	SYT1, SYT
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT1_MOUSE
θ value	8.99809 (rank : 90)	NC score	0.118562 (rank : 64)
Query Neighborhood Hits	92	Target Neighborhood Hits	150	Shared Neighborhood Hits	47
SwissProt Accessions	P46096	Gene names	Syt1
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT9_HUMAN
θ value	8.99809 (rank : 91)	NC score	0.106222 (rank : 78)
Query Neighborhood Hits	92	Target Neighborhood Hits	144	Shared Neighborhood Hits	47
SwissProt Accessions	Q86SS6	Gene names	SYT9
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX).

SYT9_MOUSE
θ value	8.99809 (rank : 92)	NC score	0.105720 (rank : 79)
Query Neighborhood Hits	92	Target Neighborhood Hits	148	Shared Neighborhood Hits	47
SwissProt Accessions	Q9R0N9, Q8C280	Gene names	Syt9, Syt5
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX) (Synaptotagmin V).

DOC2A_MOUSE
θ value	θ > 10 (rank : 93)	NC score	0.133077 (rank : 54)
Query Neighborhood Hits	92	Target Neighborhood Hits	140	Shared Neighborhood Hits	45
SwissProt Accessions	Q7TNF0	Gene names	Doc2a
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha).

DOC2G_MOUSE
θ value	θ > 10 (rank : 94)	NC score	0.120487 (rank : 62)
Query Neighborhood Hits	92	Target Neighborhood Hits	125	Shared Neighborhood Hits	43
SwissProt Accessions	Q9ESN1, Q6P8R8	Gene names	Doc2g
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein gamma (Doc2-gamma).

NCF1_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.062715 (rank : 83)
Query Neighborhood Hits	92	Target Neighborhood Hits	198	Shared Neighborhood Hits	3
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

NCF1_MOUSE
θ value	θ > 10 (rank : 96)	NC score	0.055908 (rank : 86)
Query Neighborhood Hits	92	Target Neighborhood Hits	198	Shared Neighborhood Hits	3
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

RASA3_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.057447 (rank : 85)
Query Neighborhood Hits	92	Target Neighborhood Hits	166	Shared Neighborhood Hits	41
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

RASL2_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.057665 (rank : 84)
Query Neighborhood Hits	92	Target Neighborhood Hits	161	Shared Neighborhood Hits	42
SwissProt Accessions	O43374, O60286, Q86UW3, Q96QU0	Gene names	RASA4, CAPRI, GAPL, KIAA0538
Domain Architecture
Description	Ras GTPase-activating protein 4 (RasGAP-activating-like protein 2) (Calcium-promoted Ras inactivator).

SYT10_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.106362 (rank : 77)
Query Neighborhood Hits	92	Target Neighborhood Hits	134	Shared Neighborhood Hits	46
SwissProt Accessions	Q6XYQ8	Gene names	SYT10
Domain Architecture	No domain graphic available
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

SYT12_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.122977 (rank : 57)
Query Neighborhood Hits	92	Target Neighborhood Hits	100	Shared Neighborhood Hits	46
SwissProt Accessions	Q8IV01	Gene names	SYT12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

SYT12_MOUSE
θ value	θ > 10 (rank : 101)	NC score	0.121520 (rank : 61)
Query Neighborhood Hits	92	Target Neighborhood Hits	102	Shared Neighborhood Hits	46
SwissProt Accessions	Q920N7	Gene names	Syt12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

SYT15_MOUSE
θ value	θ > 10 (rank : 102)	NC score	0.108842 (rank : 75)
Query Neighborhood Hits	92	Target Neighborhood Hits	100	Shared Neighborhood Hits	46
SwissProt Accessions	Q8C6N3, Q7TN81, Q7TN82, Q8C999	Gene names	Syt15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV).

SYT3_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.112685 (rank : 69)
Query Neighborhood Hits	92	Target Neighborhood Hits	145	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BQG1, Q8N5Z1, Q8N640	Gene names	SYT3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

SYT3_MOUSE
θ value	θ > 10 (rank : 104)	NC score	0.110795 (rank : 72)
Query Neighborhood Hits	92	Target Neighborhood Hits	147	Shared Neighborhood Hits	46
SwissProt Accessions	O35681, P97791, Q80WV1	Gene names	Syt3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

SYT4_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.109768 (rank : 73)
Query Neighborhood Hits	92	Target Neighborhood Hits	121	Shared Neighborhood Hits	46
SwissProt Accessions	Q9H2B2, Q9P2K4	Gene names	SYT4, KIAA1342
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

SYT4_MOUSE
θ value	θ > 10 (rank : 106)	NC score	0.109024 (rank : 74)
Query Neighborhood Hits	92	Target Neighborhood Hits	123	Shared Neighborhood Hits	46
SwissProt Accessions	P40749, Q3UFC1, Q8BGH3, Q8BRL6	Gene names	Syt4, Syt3
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

SYT6_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.112067 (rank : 71)
Query Neighborhood Hits	92	Target Neighborhood Hits	138	Shared Neighborhood Hits	46
SwissProt Accessions	Q5T7P8	Gene names	SYT6
Domain Architecture	No domain graphic available
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

SYT6_MOUSE
θ value	θ > 10 (rank : 108)	NC score	0.113925 (rank : 67)
Query Neighborhood Hits	92	Target Neighborhood Hits	132	Shared Neighborhood Hits	46
SwissProt Accessions	Q9R0N8	Gene names	Syt6
Domain Architecture
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

SYT7_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.116129 (rank : 65)
Query Neighborhood Hits	92	Target Neighborhood Hits	137	Shared Neighborhood Hits	46
SwissProt Accessions	O43581	Gene names	SYT7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

SYT7_MOUSE
θ value	θ > 10 (rank : 110)	NC score	0.130080 (rank : 55)
Query Neighborhood Hits	92	Target Neighborhood Hits	137	Shared Neighborhood Hits	46
SwissProt Accessions	Q9R0N7	Gene names	Syt7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

SYT8_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.087011 (rank : 80)
Query Neighborhood Hits	92	Target Neighborhood Hits	94	Shared Neighborhood Hits	45
SwissProt Accessions	Q9R0N6, Q64366, Q8C6E7	Gene names	Syt8
Domain Architecture
Description	Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII).

SYTL1_MOUSE
θ value	θ > 10 (rank : 112)	NC score	0.169297 (rank : 46)
Query Neighborhood Hits	92	Target Neighborhood Hits	314	Shared Neighborhood Hits	46
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

Hits sorted by NC score

P3C2G_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	92	Target Neighborhood Hits	92	Shared Neighborhood Hits	92
SwissProt Accessions	O75747	Gene names	PIK3C2G
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).

P3C2G_MOUSE
NC score	0.993700 (rank : 2)	θ value	0 (rank : 5)
Query Neighborhood Hits	92	Target Neighborhood Hits	113	Shared Neighborhood Hits	73
SwissProt Accessions	O70167, O70168	Gene names	Pik3c2g
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).

PK3CG_HUMAN
NC score	0.913030 (rank : 3)	θ value	9.69798e-87 (rank : 6)
Query Neighborhood Hits	92	Target Neighborhood Hits	41	Shared Neighborhood Hits	28
SwissProt Accessions	P48736, Q8IV23, Q9BZC8	Gene names	PIK3CG
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

PK3CG_MOUSE
NC score	0.911651 (rank : 4)	θ value	5.32145e-85 (rank : 8)
Query Neighborhood Hits	92	Target Neighborhood Hits	43	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JHG7	Gene names	Pik3cg, Pi3kg1
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

PK3CA_MOUSE
NC score	0.908405 (rank : 5)	θ value	1.82896e-85 (rank : 7)
Query Neighborhood Hits	92	Target Neighborhood Hits	48	Shared Neighborhood Hits	28
SwissProt Accessions	P42337	Gene names	Pik3ca
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).

PK3CA_HUMAN
NC score	0.908151 (rank : 6)	θ value	2.64101e-84 (rank : 9)
Query Neighborhood Hits	92	Target Neighborhood Hits	45	Shared Neighborhood Hits	28
SwissProt Accessions	P42336, Q99762	Gene names	PIK3CA
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).

P3C2A_MOUSE
NC score	0.906437 (rank : 7)	θ value	0 (rank : 2)
Query Neighborhood Hits	92	Target Neighborhood Hits	181	Shared Neighborhood Hits	70
SwissProt Accessions	Q61194, Q61182	Gene names	Pik3c2a, Cpk
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).

P3C2A_HUMAN
NC score	0.904715 (rank : 8)	θ value	0 (rank : 1)
Query Neighborhood Hits	92	Target Neighborhood Hits	188	Shared Neighborhood Hits	70
SwissProt Accessions	O00443	Gene names	PIK3C2A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha).

PK3CD_HUMAN
NC score	0.894318 (rank : 9)	θ value	2.3998e-69 (rank : 10)
Query Neighborhood Hits	92	Target Neighborhood Hits	40	Shared Neighborhood Hits	28
SwissProt Accessions	O00329, O15445	Gene names	PIK3CD
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit delta) (PtdIns-3- kinase p110) (PI3K) (p110delta).

PK3CD_MOUSE
NC score	0.893737 (rank : 10)	θ value	9.11921e-69 (rank : 11)
Query Neighborhood Hits	92	Target Neighborhood Hits	42	Shared Neighborhood Hits	28
SwissProt Accessions	O35904	Gene names	Pik3cd
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit delta) (PtdIns-3- kinase p110) (PI3K) (p110delta).

PK3CB_MOUSE
NC score	0.890762 (rank : 11)	θ value	1.31681e-67 (rank : 12)
Query Neighborhood Hits	92	Target Neighborhood Hits	49	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BTI9	Gene names	Pik3cb
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).

PK3CB_HUMAN
NC score	0.890416 (rank : 12)	θ value	8.53533e-67 (rank : 13)
Query Neighborhood Hits	92	Target Neighborhood Hits	43	Shared Neighborhood Hits	28
SwissProt Accessions	P42338	Gene names	PIK3CB
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).

P3C2B_HUMAN
NC score	0.887741 (rank : 13)	θ value	0 (rank : 3)
Query Neighborhood Hits	92	Target Neighborhood Hits	148	Shared Neighborhood Hits	70
SwissProt Accessions	O00750, O95666, Q5SW99	Gene names	PIK3C2B
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-beta) (PtdIns-3-kinase C2 beta) (PI3K-C2beta) (C2-PI3K).

PK3C3_HUMAN
NC score	0.844506 (rank : 14)	θ value	4.2656e-42 (rank : 14)
Query Neighborhood Hits	92	Target Neighborhood Hits	49	Shared Neighborhood Hits	28
SwissProt Accessions	Q8NEB9, Q15134	Gene names	PIK3C3
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC 2.7.1.137) (PtdIns-3-kinase type 3) (PI3-kinase type 3) (PI3K type 3) (Phosphoinositide-3-kinase class 3) (Phosphatidylinositol 3-kinase p100 subunit).

PK3C3_MOUSE
NC score	0.842887 (rank : 15)	θ value	3.61106e-41 (rank : 15)
Query Neighborhood Hits	92	Target Neighborhood Hits	49	Shared Neighborhood Hits	28
SwissProt Accessions	Q6PF93, Q8R3S8	Gene names	Pik3c3
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC 2.7.1.137) (PtdIns-3-kinase type 3) (PI3-kinase type 3) (PI3K type 3) (Phosphoinositide-3-kinase class 3).

PI4KA_HUMAN
NC score	0.809030 (rank : 16)	θ value	7.54701e-31 (rank : 16)
Query Neighborhood Hits	92	Target Neighborhood Hits	53	Shared Neighborhood Hits	28
SwissProt Accessions	P42356, Q7Z625, Q9UPG2	Gene names	PIK4CA, PIK4
Domain Architecture
Description	Phosphatidylinositol 4-kinase alpha (EC 2.7.1.67) (PI4-kinase alpha) (PtdIns-4-kinase alpha) (PI4K-alpha).

PI4KB_MOUSE
NC score	0.764934 (rank : 17)	θ value	4.01107e-24 (rank : 17)
Query Neighborhood Hits	92	Target Neighborhood Hits	67	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BKC8, Q8C146	Gene names	Pik4cb
Domain Architecture
Description	Phosphatidylinositol 4-kinase beta (EC 2.7.1.67) (PtdIns 4-kinase beta) (PI4Kbeta) (PI4K-beta).

PI4KB_HUMAN
NC score	0.762984 (rank : 18)	θ value	1.5242e-23 (rank : 18)
Query Neighborhood Hits	92	Target Neighborhood Hits	79	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UBF8, O15096, P78405, Q9BWR6	Gene names	PIK4CB, PI4KB
Domain Architecture
Description	Phosphatidylinositol 4-kinase beta (EC 2.7.1.67) (PtdIns 4-kinase beta) (PI4Kbeta) (PI4K-beta) (NPIK) (PI4K92).

FRAP_MOUSE
NC score	0.390587 (rank : 19)	θ value	1.17247e-07 (rank : 19)
Query Neighborhood Hits	92	Target Neighborhood Hits	77	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JLN9, Q811J5, Q9CST1	Gene names	Frap1, Frap
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

FRAP_HUMAN
NC score	0.389478 (rank : 20)	θ value	1.99992e-07 (rank : 20)
Query Neighborhood Hits	92	Target Neighborhood Hits	83	Shared Neighborhood Hits	28
SwissProt Accessions	P42345, Q6LE87, Q96QG3, Q9Y4I3	Gene names	FRAP1, FRAP, FRAP2
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

PRKDC_MOUSE
NC score	0.344490 (rank : 21)	θ value	0.000158464 (rank : 22)
Query Neighborhood Hits	92	Target Neighborhood Hits	92	Shared Neighborhood Hits	30
SwissProt Accessions	P97313, O88187, P97928, Q307W9, Q3V2W8, Q8C2A7, Q9Z341	Gene names	Prkdc, Xrcc7
Domain Architecture
Description	DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (P460).

PRKDC_HUMAN
NC score	0.333730 (rank : 22)	θ value	0.00175202 (rank : 33)
Query Neighborhood Hits	92	Target Neighborhood Hits	93	Shared Neighborhood Hits	28
SwissProt Accessions	P78527, P78528, Q13327, Q13337, Q14175, Q59H99, Q7Z611, Q96SE6, Q9UME3	Gene names	PRKDC
Domain Architecture
Description	DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (DNPK1) (p460).

ATR_MOUSE
NC score	0.318408 (rank : 23)	θ value	0.00020696 (rank : 26)
Query Neighborhood Hits	92	Target Neighborhood Hits	63	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JKK8	Gene names	Atr
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein).

ATR_HUMAN
NC score	0.316835 (rank : 24)	θ value	0.000602161 (rank : 29)
Query Neighborhood Hits	92	Target Neighborhood Hits	71	Shared Neighborhood Hits	28
SwissProt Accessions	Q13535, Q7KYL3, Q93051, Q9BXK4	Gene names	ATR, FRP1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein) (FRAP-related protein 1).

ATM_HUMAN
NC score	0.307354 (rank : 25)	θ value	0.00020696 (rank : 25)
Query Neighborhood Hits	92	Target Neighborhood Hits	78	Shared Neighborhood Hits	28
SwissProt Accessions	Q13315, O15429, Q12758, Q16551, Q93007, Q9NP02, Q9UCX7	Gene names	ATM
Domain Architecture
Description	Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated) (A-T, mutated).

ATM_MOUSE
NC score	0.298416 (rank : 26)	θ value	0.000270298 (rank : 27)
Query Neighborhood Hits	92	Target Neighborhood Hits	93	Shared Neighborhood Hits	28
SwissProt Accessions	Q62388	Gene names	Atm
Domain Architecture
Description	Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated homolog) (A-T, mutated homolog).

RIMS4_MOUSE
NC score	0.245494 (rank : 27)	θ value	0.00869519 (rank : 39)
Query Neighborhood Hits	92	Target Neighborhood Hits	76	Shared Neighborhood Hits	47
SwissProt Accessions	P60191	Gene names	Rims4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

RIMS4_HUMAN
NC score	0.245314 (rank : 28)	θ value	0.00869519 (rank : 38)
Query Neighborhood Hits	92	Target Neighborhood Hits	76	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H426, Q5JWT7	Gene names	RIMS4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

SMG1_MOUSE
NC score	0.236524 (rank : 29)	θ value	1.81305 (rank : 65)
Query Neighborhood Hits	92	Target Neighborhood Hits	212	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BKX6, Q5DU42, Q6ZQC0, Q8BLU4, Q8BWJ5, Q8BXD3	Gene names	Smg1, Kiaa0421
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1).

SMG1_HUMAN
NC score	0.234570 (rank : 30)	θ value	1.81305 (rank : 64)
Query Neighborhood Hits	92	Target Neighborhood Hits	231	Shared Neighborhood Hits	29
SwissProt Accessions	Q96Q15, O43305, Q13284, Q8NFX2, Q96QV0, Q96RW3	Gene names	SMG1, ATX, KIAA0421, LIP
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1) (hSMG-1) (Lambda/iota protein kinase C-interacting protein) (Lambda-interacting protein) (61E3.4).

RIMS1_HUMAN
NC score	0.219602 (rank : 31)	θ value	4.1701e-05 (rank : 21)
Query Neighborhood Hits	92	Target Neighborhood Hits	437	Shared Neighborhood Hits	47
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

SYTL3_MOUSE
NC score	0.207243 (rank : 32)	θ value	0.00665767 (rank : 36)
Query Neighborhood Hits	92	Target Neighborhood Hits	110	Shared Neighborhood Hits	47
SwissProt Accessions	Q99N48, Q8C506, Q99N47, Q99N49, Q99N54, Q99N79	Gene names	Sytl3, Slp3
Domain Architecture
Description	Synaptotagmin-like protein 3 (Exophilin-6).

RIMS2_HUMAN
NC score	0.205780 (rank : 33)	θ value	0.000158464 (rank : 23)
Query Neighborhood Hits	92	Target Neighborhood Hits	342	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
NC score	0.204938 (rank : 34)	θ value	0.000158464 (rank : 24)
Query Neighborhood Hits	92	Target Neighborhood Hits	376	Shared Neighborhood Hits	48
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

RIMS3_HUMAN
NC score	0.201492 (rank : 35)	θ value	0.00869519 (rank : 37)
Query Neighborhood Hits	92	Target Neighborhood Hits	66	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UJD0, Q92511	Gene names	RIMS3, KIAA0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

RIMS3_MOUSE
NC score	0.200437 (rank : 36)	θ value	0.00665767 (rank : 35)
Query Neighborhood Hits	92	Target Neighborhood Hits	67	Shared Neighborhood Hits	45
SwissProt Accessions	Q80U57	Gene names	Rims3, Kiaa0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

FA62A_MOUSE
NC score	0.187993 (rank : 37)	θ value	1.81305 (rank : 63)
Query Neighborhood Hits	92	Target Neighborhood Hits	155	Shared Neighborhood Hits	47
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

SYTL5_HUMAN
NC score	0.181830 (rank : 38)	θ value	0.0563607 (rank : 42)
Query Neighborhood Hits	92	Target Neighborhood Hits	237	Shared Neighborhood Hits	47
SwissProt Accessions	Q8TDW5	Gene names	SYTL5, SLP5
Domain Architecture
Description	Synaptotagmin-like protein 5.

SYTL5_MOUSE
NC score	0.181493 (rank : 39)	θ value	0.163984 (rank : 45)
Query Neighborhood Hits	92	Target Neighborhood Hits	154	Shared Neighborhood Hits	47
SwissProt Accessions	Q80T23, Q812E5	Gene names	Sytl5, Slp5
Domain Architecture
Description	Synaptotagmin-like protein 5.

SYTL1_HUMAN
NC score	0.181372 (rank : 40)	θ value	0.0961366 (rank : 44)
Query Neighborhood Hits	92	Target Neighborhood Hits	227	Shared Neighborhood Hits	48
SwissProt Accessions	Q8IYJ3, Q96BB6, Q96GU6, Q96S89, Q96SI0	Gene names	SYTL1, SLP1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1) (SB146).

SYTL2_HUMAN
NC score	0.180253 (rank : 41)	θ value	0.000602161 (rank : 30)
Query Neighborhood Hits	92	Target Neighborhood Hits	248	Shared Neighborhood Hits	47
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

SYTL2_MOUSE
NC score	0.177692 (rank : 42)	θ value	0.00298849 (rank : 34)
Query Neighborhood Hits	92	Target Neighborhood Hits	253	Shared Neighborhood Hits	45
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

FA62A_HUMAN
NC score	0.177266 (rank : 43)	θ value	0.21417 (rank : 46)
Query Neighborhood Hits	92	Target Neighborhood Hits	168	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

SYTL4_HUMAN
NC score	0.175277 (rank : 44)	θ value	0.0563607 (rank : 40)
Query Neighborhood Hits	92	Target Neighborhood Hits	138	Shared Neighborhood Hits	47
SwissProt Accessions	Q96C24, Q5H9J3, Q5JPG8, Q8N9P4, Q9H4R0, Q9H4R1	Gene names	SYTL4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

SYTL4_MOUSE
NC score	0.174385 (rank : 45)	θ value	0.0563607 (rank : 41)
Query Neighborhood Hits	92	Target Neighborhood Hits	137	Shared Neighborhood Hits	47
SwissProt Accessions	Q9R0Q1, Q8R321, Q9R0Q0	Gene names	Sytl4, Slp4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

SYTL1_MOUSE
NC score	0.169297 (rank : 46)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	92	Target Neighborhood Hits	314	Shared Neighborhood Hits	46
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

PCLO_HUMAN
NC score	0.144077 (rank : 47)	θ value	0.000786445 (rank : 31)
Query Neighborhood Hits	92	Target Neighborhood Hits	2046	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

DOC2B_HUMAN
NC score	0.140429 (rank : 48)	θ value	2.36792 (rank : 66)
Query Neighborhood Hits	92	Target Neighborhood Hits	150	Shared Neighborhood Hits	47
SwissProt Accessions	Q14184	Gene names	DOC2B
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

DOC2B_MOUSE
NC score	0.137935 (rank : 49)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	92	Target Neighborhood Hits	169	Shared Neighborhood Hits	47
SwissProt Accessions	P70169, Q6NXK3	Gene names	Doc2b
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

RP3A_HUMAN
NC score	0.137223 (rank : 50)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	92	Target Neighborhood Hits	305	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

DOC2A_HUMAN
NC score	0.134454 (rank : 51)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	92	Target Neighborhood Hits	144	Shared Neighborhood Hits	46
SwissProt Accessions	Q14183, Q6P4G4, Q7Z5G0, Q8IVX0	Gene names	DOC2A
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha) (Doc2).

PCLO_MOUSE
NC score	0.133346 (rank : 52)	θ value	0.00175202 (rank : 32)
Query Neighborhood Hits	92	Target Neighborhood Hits	2275	Shared Neighborhood Hits	52
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RP3A_MOUSE
NC score	0.133083 (rank : 53)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	92	Target Neighborhood Hits	510	Shared Neighborhood Hits	47
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

DOC2A_MOUSE
NC score	0.133077 (rank : 54)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	92	Target Neighborhood Hits	140	Shared Neighborhood Hits	45
SwissProt Accessions	Q7TNF0	Gene names	Doc2a
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha).

SYT7_MOUSE
NC score	0.130080 (rank : 55)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	92	Target Neighborhood Hits	137	Shared Neighborhood Hits	46
SwissProt Accessions	Q9R0N7	Gene names	Syt7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

SYT15_HUMAN
NC score	0.129530 (rank : 56)	θ value	0.62314 (rank : 52)
Query Neighborhood Hits	92	Target Neighborhood Hits	112	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BQS2, Q7Z439, Q7Z440	Gene names	SYT15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV) (Chr10Syt).

SYT12_HUMAN
NC score	0.122977 (rank : 57)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	92	Target Neighborhood Hits	100	Shared Neighborhood Hits	46
SwissProt Accessions	Q8IV01	Gene names	SYT12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

SYT5_HUMAN
NC score	0.122931 (rank : 58)	θ value	1.38821 (rank : 60)
Query Neighborhood Hits	92	Target Neighborhood Hits	138	Shared Neighborhood Hits	47
SwissProt Accessions	O00445, Q86X72	Gene names	SYT5
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV).

SYT2_MOUSE
NC score	0.121993 (rank : 59)	θ value	0.62314 (rank : 54)
Query Neighborhood Hits	92	Target Neighborhood Hits	143	Shared Neighborhood Hits	47
SwissProt Accessions	P46097, Q8R0E1	Gene names	Syt2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT2_HUMAN
NC score	0.121752 (rank : 60)	θ value	0.62314 (rank : 53)
Query Neighborhood Hits	92	Target Neighborhood Hits	142	Shared Neighborhood Hits	47
SwissProt Accessions	Q8N9I0, Q496K5, Q8NBE5	Gene names	SYT2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT12_MOUSE
NC score	0.121520 (rank : 61)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	92	Target Neighborhood Hits	102	Shared Neighborhood Hits	46
SwissProt Accessions	Q920N7	Gene names	Syt12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

DOC2G_MOUSE
NC score	0.120487 (rank : 62)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	92	Target Neighborhood Hits	125	Shared Neighborhood Hits	43
SwissProt Accessions	Q9ESN1, Q6P8R8	Gene names	Doc2g
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein gamma (Doc2-gamma).

SYT1_HUMAN
NC score	0.118568 (rank : 63)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	92	Target Neighborhood Hits	150	Shared Neighborhood Hits	47
SwissProt Accessions	P21579	Gene names	SYT1, SYT
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT1_MOUSE
NC score	0.118562 (rank : 64)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	92	Target Neighborhood Hits	150	Shared Neighborhood Hits	47
SwissProt Accessions	P46096	Gene names	Syt1
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT7_HUMAN
NC score	0.116129 (rank : 65)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	92	Target Neighborhood Hits	137	Shared Neighborhood Hits	46
SwissProt Accessions	O43581	Gene names	SYT7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

SYT5_MOUSE
NC score	0.114336 (rank : 66)	θ value	1.38821 (rank : 61)
Query Neighborhood Hits	92	Target Neighborhood Hits	140	Shared Neighborhood Hits	47
SwissProt Accessions	Q9R0N5	Gene names	Syt5, Syt9
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV) (Synaptotagmin IX).

SYT6_MOUSE
NC score	0.113925 (rank : 67)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	92	Target Neighborhood Hits	132	Shared Neighborhood Hits	46
SwissProt Accessions	Q9R0N8	Gene names	Syt6
Domain Architecture
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

SYT11_MOUSE
NC score	0.113452 (rank : 68)	θ value	0.279714 (rank : 48)
Query Neighborhood Hits	92	Target Neighborhood Hits	116	Shared Neighborhood Hits	47
SwissProt Accessions	Q9R0N3	Gene names	Syt11
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

SYT3_HUMAN
NC score	0.112685 (rank : 69)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	92	Target Neighborhood Hits	145	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BQG1, Q8N5Z1, Q8N640	Gene names	SYT3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

SYT11_HUMAN
NC score	0.112581 (rank : 70)	θ value	0.365318 (rank : 49)
Query Neighborhood Hits	92	Target Neighborhood Hits	113	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BT88, Q14998, Q68CT5, Q8IXU3, Q96SU2	Gene names	SYT11, KIAA0080
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

SYT6_HUMAN
NC score	0.112067 (rank : 71)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	92	Target Neighborhood Hits	138	Shared Neighborhood Hits	46
SwissProt Accessions	Q5T7P8	Gene names	SYT6
Domain Architecture	No domain graphic available
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

SYT3_MOUSE
NC score	0.110795 (rank : 72)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	92	Target Neighborhood Hits	147	Shared Neighborhood Hits	46
SwissProt Accessions	O35681, P97791, Q80WV1	Gene names	Syt3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

SYT4_HUMAN
NC score	0.109768 (rank : 73)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	92	Target Neighborhood Hits	121	Shared Neighborhood Hits	46
SwissProt Accessions	Q9H2B2, Q9P2K4	Gene names	SYT4, KIAA1342
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

SYT4_MOUSE
NC score	0.109024 (rank : 74)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	92	Target Neighborhood Hits	123	Shared Neighborhood Hits	46
SwissProt Accessions	P40749, Q3UFC1, Q8BGH3, Q8BRL6	Gene names	Syt4, Syt3
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

SYT15_MOUSE
NC score	0.108842 (rank : 75)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	92	Target Neighborhood Hits	100	Shared Neighborhood Hits	46
SwissProt Accessions	Q8C6N3, Q7TN81, Q7TN82, Q8C999	Gene names	Syt15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV).

SYT10_MOUSE
NC score	0.107745 (rank : 76)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	92	Target Neighborhood Hits	133	Shared Neighborhood Hits	47
SwissProt Accessions	Q9R0N4	Gene names	Syt10
Domain Architecture
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

SYT10_HUMAN
NC score	0.106362 (rank : 77)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	92	Target Neighborhood Hits	134	Shared Neighborhood Hits	46
SwissProt Accessions	Q6XYQ8	Gene names	SYT10
Domain Architecture	No domain graphic available
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

SYT9_HUMAN
NC score	0.106222 (rank : 78)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	92	Target Neighborhood Hits	144	Shared Neighborhood Hits	47
SwissProt Accessions	Q86SS6	Gene names	SYT9
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX).

SYT9_MOUSE
NC score	0.105720 (rank : 79)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	92	Target Neighborhood Hits	148	Shared Neighborhood Hits	47
SwissProt Accessions	Q9R0N9, Q8C280	Gene names	Syt9, Syt5
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX) (Synaptotagmin V).

SYT8_MOUSE
NC score	0.087011 (rank : 80)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	92	Target Neighborhood Hits	94	Shared Neighborhood Hits	45
SwissProt Accessions	Q9R0N6, Q64366, Q8C6E7	Gene names	Syt8
Domain Architecture
Description	Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII).

SNX27_HUMAN
NC score	0.080898 (rank : 81)	θ value	0.000270298 (rank : 28)
Query Neighborhood Hits	92	Target Neighborhood Hits	54	Shared Neighborhood Hits	7
SwissProt Accessions	Q96L92	Gene names	SNX27
Domain Architecture
Description	Sorting nexin-27.

RGS3_HUMAN
NC score	0.068092 (rank : 82)	θ value	0.62314 (rank : 51)
Query Neighborhood Hits	92	Target Neighborhood Hits	1375	Shared Neighborhood Hits	48
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

NCF1_HUMAN
NC score	0.062715 (rank : 83)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	92	Target Neighborhood Hits	198	Shared Neighborhood Hits	3
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

RASL2_HUMAN
NC score	0.057665 (rank : 84)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	92	Target Neighborhood Hits	161	Shared Neighborhood Hits	42
SwissProt Accessions	O43374, O60286, Q86UW3, Q96QU0	Gene names	RASA4, CAPRI, GAPL, KIAA0538
Domain Architecture
Description	Ras GTPase-activating protein 4 (RasGAP-activating-like protein 2) (Calcium-promoted Ras inactivator).

RASA3_HUMAN
NC score	0.057447 (rank : 85)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	92	Target Neighborhood Hits	166	Shared Neighborhood Hits	41
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

NCF1_MOUSE
NC score	0.055908 (rank : 86)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	92	Target Neighborhood Hits	198	Shared Neighborhood Hits	3
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

KPCA_HUMAN
NC score	0.039697 (rank : 87)	θ value	0.0961366 (rank : 43)
Query Neighborhood Hits	92	Target Neighborhood Hits	1070	Shared Neighborhood Hits	47
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

SNX17_HUMAN
NC score	0.039467 (rank : 88)	θ value	3.0926 (rank : 68)
Query Neighborhood Hits	92	Target Neighborhood Hits	35	Shared Neighborhood Hits	8
SwissProt Accessions	Q15036, Q53HN7, Q6IAS3	Gene names	SNX17, KIAA0064
Domain Architecture
Description	Sorting nexin-17.

KPCG_MOUSE
NC score	0.038766 (rank : 89)	θ value	0.62314 (rank : 50)
Query Neighborhood Hits	92	Target Neighborhood Hits	1123	Shared Neighborhood Hits	47
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

SNX17_MOUSE
NC score	0.037920 (rank : 90)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	92	Target Neighborhood Hits	34	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BVL3, Q8R0N8	Gene names	Snx17
Domain Architecture	No domain graphic available
Description	Sorting nexin-17.

KPCA_MOUSE
NC score	0.037264 (rank : 91)	θ value	0.21417 (rank : 47)
Query Neighborhood Hits	92	Target Neighborhood Hits	1067	Shared Neighborhood Hits	47
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KPCG_HUMAN
NC score	0.037177 (rank : 92)	θ value	1.38821 (rank : 59)
Query Neighborhood Hits	92	Target Neighborhood Hits	1126	Shared Neighborhood Hits	47
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

KPCB_HUMAN
NC score	0.034943 (rank : 93)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	92	Target Neighborhood Hits	1121	Shared Neighborhood Hits	47
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

SNX11_HUMAN
NC score	0.029663 (rank : 94)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	92	Target Neighborhood Hits	47	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y5W9, Q9H885	Gene names	SNX11
Domain Architecture
Description	Sorting nexin-11.

SNX11_MOUSE
NC score	0.029461 (rank : 95)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	92	Target Neighborhood Hits	51	Shared Neighborhood Hits	7
SwissProt Accessions	Q91WL6, Q3V3A6	Gene names	Snx11
Domain Architecture	No domain graphic available
Description	Sorting nexin-11.

PLD2_MOUSE
NC score	0.020148 (rank : 96)	θ value	0.813845 (rank : 55)
Query Neighborhood Hits	92	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	P97813	Gene names	Pld2
Domain Architecture
Description	Phospholipase D2 (EC 3.1.4.4) (PLD 2) (Choline phosphatase 2) (Phosphatidylcholine-hydrolyzing phospholipase D2) (PLD1C) (mPLD2).

UGDH_MOUSE
NC score	0.018852 (rank : 97)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	92	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	O70475	Gene names	Ugdh
Domain Architecture
Description	UDP-glucose 6-dehydrogenase (EC 1.1.1.22) (UDP-Glc dehydrogenase) (UDP-GlcDH) (UDPGDH).

UGDH_HUMAN
NC score	0.018843 (rank : 98)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	92	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	O60701, O60589	Gene names	UGDH
Domain Architecture
Description	UDP-glucose 6-dehydrogenase (EC 1.1.1.22) (UDP-Glc dehydrogenase) (UDP-GlcDH) (UDPGDH).

NFRKB_MOUSE
NC score	0.018737 (rank : 99)	θ value	1.06291 (rank : 57)
Query Neighborhood Hits	92	Target Neighborhood Hits	393	Shared Neighborhood Hits	7
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

GON4L_MOUSE
NC score	0.014732 (rank : 100)	θ value	1.38821 (rank : 58)
Query Neighborhood Hits	92	Target Neighborhood Hits	455	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

PLD1_HUMAN
NC score	0.014457 (rank : 101)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	92	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	Q13393	Gene names	PLD1
Domain Architecture
Description	Phospholipase D1 (EC 3.1.4.4) (PLD 1) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1) (hPLD1).

CB010_HUMAN
NC score	0.013271 (rank : 102)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	92	Target Neighborhood Hits	130	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z570, Q6ZN26	Gene names	C2orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf10.

ZFY28_HUMAN
NC score	0.010965 (rank : 103)	θ value	2.36792 (rank : 67)
Query Neighborhood Hits	92	Target Neighborhood Hits	152	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HCC9	Gene names	ZFYVE28, KIAA1643
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 28.

STON1_HUMAN
NC score	0.008105 (rank : 104)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	92	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y6Q2, Q96JE3, Q9BYX3	Gene names	STON1, SALF, SBLF, STN1
Domain Architecture
Description	Stonin-1 (Stoned B-like factor).

CCHCR_MOUSE
NC score	0.003785 (rank : 105)	θ value	1.81305 (rank : 62)
Query Neighborhood Hits	92	Target Neighborhood Hits	932	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

MTA2_HUMAN
NC score	0.003713 (rank : 106)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	92	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	O94776, Q9UQB5	Gene names	MTA2, MTA1L1, PID
Domain Architecture
Description	Metastasis-associated protein MTA2 (Metastasis-associated 1-like 1) (MTA1-L1 protein) (p53 target protein in deacetylase complex).

IFT74_HUMAN
NC score	0.003611 (rank : 107)	θ value	1.06291 (rank : 56)
Query Neighborhood Hits	92	Target Neighborhood Hits	949	Shared Neighborhood Hits	7
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

DNJA4_HUMAN
NC score	0.003264 (rank : 108)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	92	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WW22, Q8N7P2	Gene names	DNAJA4
Domain Architecture
Description	DnaJ homolog subfamily A member 4.

DNJA4_MOUSE
NC score	0.003242 (rank : 109)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	92	Target Neighborhood Hits	87	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JMC3, Q543S9, Q9CTD6, Q9CUD4	Gene names	Dnaja4
Domain Architecture
Description	DnaJ homolog subfamily A member 4 (MmDjA4).

SEPT4_HUMAN
NC score	0.003176 (rank : 110)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	92	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	O43236, Q9UM58	Gene names	SEPT4, PNUTL2
Domain Architecture
Description	Septin-4 (Peanut-like protein 2) (Brain protein H5) (Cell division control-related protein 2) (hCDCREL-2) (Bradeion beta) (CE5B3 beta) (Cerebral protein 7).

DHX36_HUMAN
NC score	0.002679 (rank : 111)	θ value	8.99809 (rank : 83)
Query Neighborhood Hits	92	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H2U1, Q70JU3, Q8IYE5, Q9P240	Gene names	DHX36, DDX36, KIAA1488, MLEL1, RHAU
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

TRIM8_HUMAN
NC score	0.002610 (rank : 112)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	92	Target Neighborhood Hits	650	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).