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Network neighborhood for query Sequence : CB010_HUMAN

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CB010_HUMAN
SwissProt Accessions	Q7Z570, Q6ZN26	Gene names	C2orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf10.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CB010_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	130	Target Neighborhood Hits	130	Shared Neighborhood Hits	130
SwissProt Accessions	Q7Z570, Q6ZN26	Gene names	C2orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf10.

GPTC8_HUMAN
θ value	1.42992e-13 (rank : 2)	NC score	0.307048 (rank : 2)
Query Neighborhood Hits	130	Target Neighborhood Hits	366	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

HOOK1_MOUSE
θ value	0.00509761 (rank : 3)	NC score	0.077907 (rank : 7)
Query Neighborhood Hits	130	Target Neighborhood Hits	910	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

RAI14_HUMAN
θ value	0.00665767 (rank : 4)	NC score	0.050373 (rank : 23)
Query Neighborhood Hits	130	Target Neighborhood Hits	1367	Shared Neighborhood Hits	46
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

DPOLQ_HUMAN
θ value	0.0148317 (rank : 5)	NC score	0.112022 (rank : 3)
Query Neighborhood Hits	130	Target Neighborhood Hits	67	Shared Neighborhood Hits	5
SwissProt Accessions	O75417, O95160	Gene names	POLQ, POLH
Domain Architecture
Description	DNA polymerase theta (EC 2.7.7.7) (DNA polymerase eta).

YLPM1_MOUSE
θ value	0.0252991 (rank : 6)	NC score	0.086039 (rank : 6)
Query Neighborhood Hits	130	Target Neighborhood Hits	505	Shared Neighborhood Hits	14
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

ATRX_HUMAN
θ value	0.0330416 (rank : 7)	NC score	0.072666 (rank : 9)
Query Neighborhood Hits	130	Target Neighborhood Hits	842	Shared Neighborhood Hits	45
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

HOOK1_HUMAN
θ value	0.0330416 (rank : 8)	NC score	0.075078 (rank : 8)
Query Neighborhood Hits	130	Target Neighborhood Hits	942	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

MLL3_MOUSE
θ value	0.0563607 (rank : 9)	NC score	0.055215 (rank : 16)
Query Neighborhood Hits	130	Target Neighborhood Hits	1399	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

ROCK1_MOUSE
θ value	0.125558 (rank : 10)	NC score	0.031327 (rank : 74)
Query Neighborhood Hits	130	Target Neighborhood Hits	2126	Shared Neighborhood Hits	54
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

PIAS1_MOUSE
θ value	0.163984 (rank : 11)	NC score	0.054857 (rank : 17)
Query Neighborhood Hits	130	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	O88907, Q8C6H5	Gene names	Pias1, Ddxbp1
Domain Architecture
Description	Protein inhibitor of activated STAT protein 1 (DEAD/H box-binding protein 1).

CA026_HUMAN
θ value	0.279714 (rank : 12)	NC score	0.102043 (rank : 4)
Query Neighborhood Hits	130	Target Neighborhood Hits	87	Shared Neighborhood Hits	12
SwissProt Accessions	Q5T5J6, Q8NEK9, Q9BZQ7, Q9NXQ0	Gene names	C1orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf26.

CA026_MOUSE
θ value	0.279714 (rank : 13)	NC score	0.095814 (rank : 5)
Query Neighborhood Hits	130	Target Neighborhood Hits	100	Shared Neighborhood Hits	10
SwissProt Accessions	Q9DBQ9, Q6PAN2, Q7TMQ6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf26 homolog.

EDEM3_HUMAN
θ value	0.279714 (rank : 14)	NC score	0.049939 (rank : 24)
Query Neighborhood Hits	130	Target Neighborhood Hits	92	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BZQ6, Q5TEZ0, Q9HCW1, Q9UFV7	Gene names	EDEM3, C1orf22
Domain Architecture
Description	ER degradation-enhancing alpha-mannosidase-like 3.

KCTD3_HUMAN
θ value	0.365318 (rank : 15)	NC score	0.047280 (rank : 30)
Query Neighborhood Hits	130	Target Neighborhood Hits	90	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y597, Q49AG7, Q504Q9, Q6PJN6, Q8ND58, Q8NDJ0, Q8WX16	Gene names	KCTD3
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD3 (NY-REN-45 antigen).

MTF1_HUMAN
θ value	0.365318 (rank : 16)	NC score	0.017682 (rank : 102)
Query Neighborhood Hits	130	Target Neighborhood Hits	814	Shared Neighborhood Hits	19
SwissProt Accessions	Q14872, Q96CB1	Gene names	MTF1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

PO121_MOUSE
θ value	0.62314 (rank : 17)	NC score	0.051994 (rank : 19)
Query Neighborhood Hits	130	Target Neighborhood Hits	345	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

SON_HUMAN
θ value	0.62314 (rank : 18)	NC score	0.038054 (rank : 57)
Query Neighborhood Hits	130	Target Neighborhood Hits	1568	Shared Neighborhood Hits	36
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

WNK4_MOUSE
θ value	0.62314 (rank : 19)	NC score	0.022999 (rank : 96)
Query Neighborhood Hits	130	Target Neighborhood Hits	961	Shared Neighborhood Hits	19
SwissProt Accessions	Q80UE6, Q4VAC1, Q80XB5, Q80XN2, Q8R0N0, Q8R340	Gene names	Wnk4, Prkwnk4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

ATN1_HUMAN
θ value	0.813845 (rank : 20)	NC score	0.058575 (rank : 13)
Query Neighborhood Hits	130	Target Neighborhood Hits	676	Shared Neighborhood Hits	21
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

CBPB2_HUMAN
θ value	0.813845 (rank : 21)	NC score	0.027329 (rank : 85)
Query Neighborhood Hits	130	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q96IY4, Q15114, Q5T9K1, Q5T9K2, Q9P2Y6	Gene names	CPB2
Domain Architecture	No domain graphic available
Description	Carboxypeptidase B2 precursor (EC 3.4.17.20) (Carboxypeptidase U) (CPU) (Thrombin-activable fibrinolysis inhibitor) (TAFI) (Plasma carboxypeptidase B) (pCPB).

EP15_MOUSE
θ value	0.813845 (rank : 22)	NC score	0.045082 (rank : 36)
Query Neighborhood Hits	130	Target Neighborhood Hits	820	Shared Neighborhood Hits	31
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

SOX13_MOUSE
θ value	0.813845 (rank : 23)	NC score	0.034777 (rank : 68)
Query Neighborhood Hits	130	Target Neighborhood Hits	495	Shared Neighborhood Hits	21
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

TLK2_HUMAN
θ value	0.813845 (rank : 24)	NC score	0.023561 (rank : 95)
Query Neighborhood Hits	130	Target Neighborhood Hits	1044	Shared Neighborhood Hits	30
SwissProt Accessions	Q86UE8, Q9UKI7, Q9Y4F7	Gene names	TLK2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2) (PKU-alpha).

TLK2_MOUSE
θ value	0.813845 (rank : 25)	NC score	0.024680 (rank : 89)
Query Neighborhood Hits	130	Target Neighborhood Hits	1088	Shared Neighborhood Hits	33
SwissProt Accessions	O55047, Q9D5Y5	Gene names	Tlk2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2).

USH1C_MOUSE
θ value	0.813845 (rank : 26)	NC score	0.038373 (rank : 56)
Query Neighborhood Hits	130	Target Neighborhood Hits	557	Shared Neighborhood Hits	24
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

ANR12_HUMAN
θ value	1.38821 (rank : 27)	NC score	0.038012 (rank : 58)
Query Neighborhood Hits	130	Target Neighborhood Hits	1081	Shared Neighborhood Hits	48
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

CENPE_HUMAN
θ value	1.38821 (rank : 28)	NC score	0.041952 (rank : 47)
Query Neighborhood Hits	130	Target Neighborhood Hits	2060	Shared Neighborhood Hits	61
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CLSPN_HUMAN
θ value	1.38821 (rank : 29)	NC score	0.048144 (rank : 27)
Query Neighborhood Hits	130	Target Neighborhood Hits	433	Shared Neighborhood Hits	28
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

PIAS1_HUMAN
θ value	1.38821 (rank : 30)	NC score	0.045735 (rank : 35)
Query Neighborhood Hits	130	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	O75925, Q99751, Q9UN02	Gene names	PIAS1, DDXBP1
Domain Architecture
Description	Protein inhibitor of activated STAT protein 1 (Gu-binding protein) (GBP) (RNA helicase II-binding protein) (DEAD/H box-binding protein 1).

SRRM2_HUMAN
θ value	1.38821 (rank : 31)	NC score	0.034408 (rank : 70)
Query Neighborhood Hits	130	Target Neighborhood Hits	1296	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

STK10_MOUSE
θ value	1.38821 (rank : 32)	NC score	0.028116 (rank : 82)
Query Neighborhood Hits	130	Target Neighborhood Hits	2132	Shared Neighborhood Hits	57
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

ZN611_HUMAN
θ value	1.38821 (rank : 33)	NC score	0.009919 (rank : 128)
Query Neighborhood Hits	130	Target Neighborhood Hits	769	Shared Neighborhood Hits	21
SwissProt Accessions	Q8N823, Q69YG9	Gene names	ZNF611
Domain Architecture	No domain graphic available
Description	Zinc finger protein 611.

ZN622_MOUSE
θ value	1.38821 (rank : 34)	NC score	0.067489 (rank : 11)
Query Neighborhood Hits	130	Target Neighborhood Hits	28	Shared Neighborhood Hits	6
SwissProt Accessions	Q91VY9	Gene names	Znf622, D15Ertd806e, Zfp622
Domain Architecture	No domain graphic available
Description	Zinc finger protein 622.

AUTS2_HUMAN
θ value	1.81305 (rank : 35)	NC score	0.047475 (rank : 28)
Query Neighborhood Hits	130	Target Neighborhood Hits	342	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

CENPU_HUMAN
θ value	1.81305 (rank : 36)	NC score	0.060266 (rank : 12)
Query Neighborhood Hits	130	Target Neighborhood Hits	289	Shared Neighborhood Hits	23
SwissProt Accessions	Q71F23, Q32Q71, Q9H5G1	Gene names	MLF1IP, CENPU, ICEN24, KLIP1
Domain Architecture	No domain graphic available
Description	Centromere protein U (CENP-U) (CENP-U(50)) (CENP-50) (Interphase centromere complex protein 24) (MLF1-interacting protein) (KSHV latent nuclear antigen-interacting protein 1).

FA76B_HUMAN
θ value	1.81305 (rank : 37)	NC score	0.051997 (rank : 18)
Query Neighborhood Hits	130	Target Neighborhood Hits	184	Shared Neighborhood Hits	16
SwissProt Accessions	Q5HYJ3, Q6PIU3, Q8TC53	Gene names	FAM76B
Domain Architecture	No domain graphic available
Description	Protein FAM76B.

HXA4_HUMAN
θ value	1.81305 (rank : 38)	NC score	0.010659 (rank : 126)
Query Neighborhood Hits	130	Target Neighborhood Hits	370	Shared Neighborhood Hits	4
SwissProt Accessions	Q00056, O43366	Gene names	HOXA4, HOX1D
Domain Architecture
Description	Homeobox protein Hox-A4 (Hox-1D) (Hox-1.4).

MYH9_HUMAN
θ value	1.81305 (rank : 39)	NC score	0.030602 (rank : 77)
Query Neighborhood Hits	130	Target Neighborhood Hits	1762	Shared Neighborhood Hits	56
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

PKD1_HUMAN
θ value	1.81305 (rank : 40)	NC score	0.025129 (rank : 86)
Query Neighborhood Hits	130	Target Neighborhood Hits	387	Shared Neighborhood Hits	4
SwissProt Accessions	P98161, Q15140, Q15141	Gene names	PKD1
Domain Architecture
Description	Polycystin-1 precursor (Autosomal dominant polycystic kidney disease protein 1).

RBBP8_HUMAN
θ value	1.81305 (rank : 41)	NC score	0.069207 (rank : 10)
Query Neighborhood Hits	130	Target Neighborhood Hits	476	Shared Neighborhood Hits	42
SwissProt Accessions	Q99708, O75371	Gene names	RBBP8, CTIP
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 8 (RBBP-8) (CtBP-interacting protein) (CtIP) (Retinoblastoma-interacting protein and myosin-like) (RIM).

ATRX_MOUSE
θ value	2.36792 (rank : 42)	NC score	0.055357 (rank : 15)
Query Neighborhood Hits	130	Target Neighborhood Hits	682	Shared Neighborhood Hits	37
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

ERF_HUMAN
θ value	2.36792 (rank : 43)	NC score	0.030379 (rank : 78)
Query Neighborhood Hits	130	Target Neighborhood Hits	162	Shared Neighborhood Hits	6
SwissProt Accessions	P50548, Q9UPI7	Gene names	ERF
Domain Architecture
Description	ETS domain-containing transcription factor ERF (Ets2 repressor factor).

ERF_MOUSE
θ value	2.36792 (rank : 44)	NC score	0.030255 (rank : 79)
Query Neighborhood Hits	130	Target Neighborhood Hits	160	Shared Neighborhood Hits	6
SwissProt Accessions	P70459	Gene names	Erf
Domain Architecture
Description	ETS domain-containing transcription factor ERF.

ITSN1_HUMAN
θ value	2.36792 (rank : 45)	NC score	0.039095 (rank : 54)
Query Neighborhood Hits	130	Target Neighborhood Hits	1757	Shared Neighborhood Hits	56
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

KLF11_HUMAN
θ value	2.36792 (rank : 46)	NC score	0.016379 (rank : 106)
Query Neighborhood Hits	130	Target Neighborhood Hits	717	Shared Neighborhood Hits	18
SwissProt Accessions	O14901	Gene names	KLF11, FKLF, TIEG2
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 11 (Transforming growth factor-beta-inducible early growth response protein 2) (TGFB-inducible early growth response protein 2) (TIEG-2).

KLF11_MOUSE
θ value	2.36792 (rank : 47)	NC score	0.016428 (rank : 105)
Query Neighborhood Hits	130	Target Neighborhood Hits	714	Shared Neighborhood Hits	18
SwissProt Accessions	Q9EPF4	Gene names	Klf11, Tieg2
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 11 (Transforming growth factor-beta-inducible early growth response protein 2) (TGFB-inducible early growth response protein 2) (TIEG-2).

PCD15_HUMAN
θ value	2.36792 (rank : 48)	NC score	0.010680 (rank : 125)
Query Neighborhood Hits	130	Target Neighborhood Hits	289	Shared Neighborhood Hits	5
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

SLK_HUMAN
θ value	2.36792 (rank : 49)	NC score	0.024840 (rank : 88)
Query Neighborhood Hits	130	Target Neighborhood Hits	1775	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

ANKZ1_HUMAN
θ value	3.0926 (rank : 50)	NC score	0.039252 (rank : 53)
Query Neighborhood Hits	130	Target Neighborhood Hits	236	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

ARHG2_HUMAN
θ value	3.0926 (rank : 51)	NC score	0.033982 (rank : 71)
Query Neighborhood Hits	130	Target Neighborhood Hits	142	Shared Neighborhood Hits	9
SwissProt Accessions	Q92974, O75142, Q15079	Gene names	ARHGEF2, KIAA0651, LFP40
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (GEF-H1 protein) (Proliferating cell nucleolar antigen p40).

BAG3_HUMAN
θ value	3.0926 (rank : 52)	NC score	0.027958 (rank : 83)
Query Neighborhood Hits	130	Target Neighborhood Hits	314	Shared Neighborhood Hits	9
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

BRCA2_MOUSE
θ value	3.0926 (rank : 53)	NC score	0.035989 (rank : 66)
Query Neighborhood Hits	130	Target Neighborhood Hits	222	Shared Neighborhood Hits	15
SwissProt Accessions	P97929, O35922, P97383	Gene names	Brca2, Fancd1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein homolog (Fanconi anemia group D1 protein homolog).

CE025_HUMAN
θ value	3.0926 (rank : 54)	NC score	0.047433 (rank : 29)
Query Neighborhood Hits	130	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NDZ2, Q6NXN8, Q6ZTU4, Q8IZ15	Gene names	C5orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C5orf25.

LUZP1_HUMAN
θ value	3.0926 (rank : 55)	NC score	0.045944 (rank : 34)
Query Neighborhood Hits	130	Target Neighborhood Hits	739	Shared Neighborhood Hits	34
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

RNF17_MOUSE
θ value	3.0926 (rank : 56)	NC score	0.037701 (rank : 60)
Query Neighborhood Hits	130	Target Neighborhood Hits	147	Shared Neighborhood Hits	11
SwissProt Accessions	Q99MV7	Gene names	Rnf17
Domain Architecture
Description	RING finger protein 17.

SAFB2_MOUSE
θ value	3.0926 (rank : 57)	NC score	0.043664 (rank : 40)
Query Neighborhood Hits	130	Target Neighborhood Hits	581	Shared Neighborhood Hits	33
SwissProt Accessions	Q80YR5, Q8K153	Gene names	Safb2
Domain Architecture
Description	Scaffold attachment factor B2.

SLK_MOUSE
θ value	3.0926 (rank : 58)	NC score	0.023995 (rank : 92)
Query Neighborhood Hits	130	Target Neighborhood Hits	1798	Shared Neighborhood Hits	56
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

WNK2_HUMAN
θ value	3.0926 (rank : 59)	NC score	0.020403 (rank : 99)
Query Neighborhood Hits	130	Target Neighborhood Hits	1407	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

ZN131_HUMAN
θ value	3.0926 (rank : 60)	NC score	0.015443 (rank : 109)
Query Neighborhood Hits	130	Target Neighborhood Hits	833	Shared Neighborhood Hits	22
SwissProt Accessions	P52739, Q6PIF0	Gene names	ZNF131
Domain Architecture	No domain graphic available
Description	Zinc finger protein 131.

ZN131_MOUSE
θ value	3.0926 (rank : 61)	NC score	0.015247 (rank : 110)
Query Neighborhood Hits	130	Target Neighborhood Hits	833	Shared Neighborhood Hits	22
SwissProt Accessions	Q8K3J5, Q3UYZ4, Q80UU7, Q8C8D0, Q9D042	Gene names	Znf131, Zfp131
Domain Architecture	No domain graphic available
Description	Zinc finger protein 131.

ZN622_HUMAN
θ value	3.0926 (rank : 62)	NC score	0.058545 (rank : 14)
Query Neighborhood Hits	130	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	Q969S3	Gene names	ZNF622, ZPR9
Domain Architecture	No domain graphic available
Description	Zinc finger protein 622 (Zinc finger-like protein 9).

CENPF_HUMAN
θ value	4.03905 (rank : 63)	NC score	0.044697 (rank : 39)
Query Neighborhood Hits	130	Target Neighborhood Hits	1932	Shared Neighborhood Hits	63
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CF152_MOUSE
θ value	4.03905 (rank : 64)	NC score	0.046560 (rank : 33)
Query Neighborhood Hits	130	Target Neighborhood Hits	597	Shared Neighborhood Hits	34
SwissProt Accessions	Q80ST9, Q9CYM9, Q9D5J9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf152 homolog.

MTF1_MOUSE
θ value	4.03905 (rank : 65)	NC score	0.014896 (rank : 112)
Query Neighborhood Hits	130	Target Neighborhood Hits	785	Shared Neighborhood Hits	20
SwissProt Accessions	Q07243	Gene names	Mtf1, Mtf-1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

NAF1_MOUSE
θ value	4.03905 (rank : 66)	NC score	0.048218 (rank : 26)
Query Neighborhood Hits	130	Target Neighborhood Hits	852	Shared Neighborhood Hits	42
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

PRD16_HUMAN
θ value	4.03905 (rank : 67)	NC score	0.012025 (rank : 121)
Query Neighborhood Hits	130	Target Neighborhood Hits	832	Shared Neighborhood Hits	25
SwissProt Accessions	Q9HAZ2, Q8WYJ9, Q9C0I8	Gene names	PRDM16, KIAA1675, MEL1, PFM13
Domain Architecture
Description	PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1).

RIF1_HUMAN
θ value	4.03905 (rank : 68)	NC score	0.038719 (rank : 55)
Query Neighborhood Hits	130	Target Neighborhood Hits	320	Shared Neighborhood Hits	25
SwissProt Accessions	Q5UIP0, Q5H9R3, Q5UIP2, Q66YK6, Q6PRU2, Q8TE94, Q99772, Q9H830, Q9H9B9, Q9NVP5, Q9Y4R4	Gene names	RIF1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog).

S2A4R_HUMAN
θ value	4.03905 (rank : 69)	NC score	0.045054 (rank : 38)
Query Neighborhood Hits	130	Target Neighborhood Hits	54	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NR83, Q6F6I6, Q6F6I7, Q6GTK5, Q8TAH5, Q8WVW7, Q96QD3, Q9BV85	Gene names	SLC2A4RG, HDBP1
Domain Architecture	No domain graphic available
Description	SLC2A4 regulator (GLUT4 enhancer factor) (GEF) (Huntington disease gene regulatory region-binding protein 1) (HDBP-1).

SGOL2_HUMAN
θ value	4.03905 (rank : 70)	NC score	0.043035 (rank : 43)
Query Neighborhood Hits	130	Target Neighborhood Hits	207	Shared Neighborhood Hits	15
SwissProt Accessions	Q562F6, Q53RR9, Q53T20, Q86XY4, Q8IWK2, Q8IZK1, Q8N1Q5, Q96LQ3	Gene names	SGOL2
Domain Architecture	No domain graphic available
Description	Shugoshin-like 2 (Tripin).

SUHW4_HUMAN
θ value	4.03905 (rank : 71)	NC score	0.017649 (rank : 103)
Query Neighborhood Hits	130	Target Neighborhood Hits	860	Shared Neighborhood Hits	33
SwissProt Accessions	Q6N043, Q6MZM6, Q6N085, Q9H0U5, Q9HCI8, Q9NXS0	Gene names	SUHW4, KIAA1584
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

TRI45_MOUSE
θ value	4.03905 (rank : 72)	NC score	0.018033 (rank : 101)
Query Neighborhood Hits	130	Target Neighborhood Hits	155	Shared Neighborhood Hits	9
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

ZBT11_HUMAN
θ value	4.03905 (rank : 73)	NC score	0.011044 (rank : 123)
Query Neighborhood Hits	130	Target Neighborhood Hits	873	Shared Neighborhood Hits	22
SwissProt Accessions	O95625	Gene names	ZBTB11
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 11.

ZN701_HUMAN
θ value	4.03905 (rank : 74)	NC score	0.009505 (rank : 129)
Query Neighborhood Hits	130	Target Neighborhood Hits	747	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NV72, Q66K42	Gene names	ZNF701
Domain Architecture	No domain graphic available
Description	Zinc finger protein 701.

CD008_HUMAN
θ value	5.27518 (rank : 75)	NC score	0.039325 (rank : 52)
Query Neighborhood Hits	130	Target Neighborhood Hits	330	Shared Neighborhood Hits	25
SwissProt Accessions	P78312, O43607, P78311, P78313, Q9UEG8	Gene names	C4orf8
Domain Architecture	No domain graphic available
Description	Protein C4orf8 (Protein IT14).

CTRO_HUMAN
θ value	5.27518 (rank : 76)	NC score	0.024494 (rank : 90)
Query Neighborhood Hits	130	Target Neighborhood Hits	2092	Shared Neighborhood Hits	50
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

CYTSA_HUMAN
θ value	5.27518 (rank : 77)	NC score	0.042044 (rank : 46)
Query Neighborhood Hits	130	Target Neighborhood Hits	1138	Shared Neighborhood Hits	42
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

DPF3_HUMAN
θ value	5.27518 (rank : 78)	NC score	0.032808 (rank : 73)
Query Neighborhood Hits	130	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q92784, Q9H7Y5	Gene names	DPF3, CERD4
Domain Architecture	No domain graphic available
Description	Zinc-finger protein DPF3 (cer-d4).

FA76B_MOUSE
θ value	5.27518 (rank : 79)	NC score	0.045055 (rank : 37)
Query Neighborhood Hits	130	Target Neighborhood Hits	181	Shared Neighborhood Hits	18
SwissProt Accessions	Q80XP8, Q3UMA6, Q80YR1, Q8CI69	Gene names	Fam76b
Domain Architecture	No domain graphic available
Description	Protein FAM76B.

NAF1_HUMAN
θ value	5.27518 (rank : 80)	NC score	0.049777 (rank : 25)
Query Neighborhood Hits	130	Target Neighborhood Hits	937	Shared Neighborhood Hits	41
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

P3C2G_HUMAN
θ value	5.27518 (rank : 81)	NC score	0.013271 (rank : 119)
Query Neighborhood Hits	130	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	O75747	Gene names	PIK3C2G
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).

PRD10_HUMAN
θ value	5.27518 (rank : 82)	NC score	0.011779 (rank : 122)
Query Neighborhood Hits	130	Target Neighborhood Hits	769	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NQV6, Q9ULI9	Gene names	PRDM10, KIAA1231, PFM7
Domain Architecture	No domain graphic available
Description	PR domain zinc finger protein 10 (PR domain-containing protein 10).

PROX1_MOUSE
θ value	5.27518 (rank : 83)	NC score	0.033862 (rank : 72)
Query Neighborhood Hits	130	Target Neighborhood Hits	184	Shared Neighborhood Hits	17
SwissProt Accessions	P48437, O88478, Q3UPV1, Q543D8	Gene names	Prox1
Domain Architecture
Description	Homeobox prospero-like protein PROX1 (PROX 1).

PZP_HUMAN
θ value	5.27518 (rank : 84)	NC score	0.013892 (rank : 116)
Query Neighborhood Hits	130	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	P20742, Q15273	Gene names	PZP
Domain Architecture
Description	Pregnancy zone protein precursor.

REQU_MOUSE
θ value	5.27518 (rank : 85)	NC score	0.027458 (rank : 84)
Query Neighborhood Hits	130	Target Neighborhood Hits	519	Shared Neighborhood Hits	13
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

RLF_HUMAN
θ value	5.27518 (rank : 86)	NC score	0.018230 (rank : 100)
Query Neighborhood Hits	130	Target Neighborhood Hits	775	Shared Neighborhood Hits	23
SwissProt Accessions	Q13129, Q9NU60	Gene names	RLF
Domain Architecture	No domain graphic available
Description	Zinc finger protein Rlf (Rearranged L-myc fusion gene protein) (Zn-15- related protein).

SAFB2_HUMAN
θ value	5.27518 (rank : 87)	NC score	0.043131 (rank : 42)
Query Neighborhood Hits	130	Target Neighborhood Hits	720	Shared Neighborhood Hits	33
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

TLR5_HUMAN
θ value	5.27518 (rank : 88)	NC score	0.008532 (rank : 130)
Query Neighborhood Hits	130	Target Neighborhood Hits	288	Shared Neighborhood Hits	3
SwissProt Accessions	O60602, O15456	Gene names	TLR5, TIL3
Domain Architecture
Description	Toll-like receptor 5 precursor (Toll/interleukin-1 receptor-like protein 3).

TP53B_HUMAN
θ value	5.27518 (rank : 89)	NC score	0.030651 (rank : 76)
Query Neighborhood Hits	130	Target Neighborhood Hits	413	Shared Neighborhood Hits	23
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

UACA_HUMAN
θ value	5.27518 (rank : 90)	NC score	0.040453 (rank : 50)
Query Neighborhood Hits	130	Target Neighborhood Hits	1622	Shared Neighborhood Hits	57
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

UBP47_MOUSE
θ value	5.27518 (rank : 91)	NC score	0.013550 (rank : 117)
Query Neighborhood Hits	130	Target Neighborhood Hits	135	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UTY_MOUSE
θ value	5.27518 (rank : 92)	NC score	0.021414 (rank : 97)
Query Neighborhood Hits	130	Target Neighborhood Hits	64	Shared Neighborhood Hits	3
SwissProt Accessions	P79457, O97979	Gene names	Uty
Domain Architecture
Description	Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein (Ubiquitously transcribed TPR protein ON the Y chromosome) (Male- specific histocompatibility antigen H-YDB).

ARHG2_MOUSE
θ value	6.88961 (rank : 93)	NC score	0.028978 (rank : 81)
Query Neighborhood Hits	130	Target Neighborhood Hits	120	Shared Neighborhood Hits	9
SwissProt Accessions	Q60875, O09115	Gene names	Arhgef2, Lbcl1, Lfc
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (Lymphoid blast crisis- like 1) (LBC'S first cousin) (Oncogene LFC) (RHOBIN).

ATR_MOUSE
θ value	6.88961 (rank : 94)	NC score	0.014994 (rank : 111)
Query Neighborhood Hits	130	Target Neighborhood Hits	63	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JKK8	Gene names	Atr
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein).

CCD46_HUMAN
θ value	6.88961 (rank : 95)	NC score	0.047191 (rank : 31)
Query Neighborhood Hits	130	Target Neighborhood Hits	1430	Shared Neighborhood Hits	52
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

CCD46_MOUSE
θ value	6.88961 (rank : 96)	NC score	0.046867 (rank : 32)
Query Neighborhood Hits	130	Target Neighborhood Hits	1405	Shared Neighborhood Hits	52
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

CYTSA_MOUSE
θ value	6.88961 (rank : 97)	NC score	0.042839 (rank : 44)
Query Neighborhood Hits	130	Target Neighborhood Hits	1104	Shared Neighborhood Hits	43
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

DMP1_HUMAN
θ value	6.88961 (rank : 98)	NC score	0.036765 (rank : 63)
Query Neighborhood Hits	130	Target Neighborhood Hits	491	Shared Neighborhood Hits	31
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

DNMBP_HUMAN
θ value	6.88961 (rank : 99)	NC score	0.017308 (rank : 104)
Query Neighborhood Hits	130	Target Neighborhood Hits	413	Shared Neighborhood Hits	14
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

EEA1_HUMAN
θ value	6.88961 (rank : 100)	NC score	0.040513 (rank : 49)
Query Neighborhood Hits	130	Target Neighborhood Hits	1796	Shared Neighborhood Hits	56
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

EEA1_MOUSE
θ value	6.88961 (rank : 101)	NC score	0.037921 (rank : 59)
Query Neighborhood Hits	130	Target Neighborhood Hits	1637	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

FGF1_MOUSE
θ value	6.88961 (rank : 102)	NC score	0.012117 (rank : 120)
Query Neighborhood Hits	130	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	P61148, P10935	Gene names	Fgf1, Fgf-1, Fgfa
Domain Architecture
Description	Heparin-binding growth factor 1 precursor (HBGF-1) (Acidic fibroblast growth factor) (aFGF).

FOXJ3_HUMAN
θ value	6.88961 (rank : 103)	NC score	0.007729 (rank : 133)
Query Neighborhood Hits	130	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UPW0, Q9NSS7	Gene names	FOXJ3, KIAA1041
Domain Architecture
Description	Forkhead box protein J3.

GOGB1_HUMAN
θ value	6.88961 (rank : 104)	NC score	0.043624 (rank : 41)
Query Neighborhood Hits	130	Target Neighborhood Hits	2297	Shared Neighborhood Hits	66
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

GP73_MOUSE
θ value	6.88961 (rank : 105)	NC score	0.041572 (rank : 48)
Query Neighborhood Hits	130	Target Neighborhood Hits	506	Shared Neighborhood Hits	32
SwissProt Accessions	Q91XA2	Gene names	Golph2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

NKX61_MOUSE
θ value	6.88961 (rank : 106)	NC score	0.008313 (rank : 131)
Query Neighborhood Hits	130	Target Neighborhood Hits	439	Shared Neighborhood Hits	6
SwissProt Accessions	Q99MA9, Q9ERQ7	Gene names	Nkx6-1, Nkx6.1, Nkx6a
Domain Architecture
Description	Homeobox protein Nkx-6.1.

NUCB2_MOUSE
θ value	6.88961 (rank : 107)	NC score	0.030975 (rank : 75)
Query Neighborhood Hits	130	Target Neighborhood Hits	459	Shared Neighborhood Hits	30
SwissProt Accessions	P81117	Gene names	Nucb2, Nefa
Domain Architecture	No domain graphic available
Description	Nucleobindin-2 precursor (DNA-binding protein NEFA).

RERE_MOUSE
θ value	6.88961 (rank : 108)	NC score	0.036951 (rank : 61)
Query Neighborhood Hits	130	Target Neighborhood Hits	785	Shared Neighborhood Hits	21
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

RN168_MOUSE
θ value	6.88961 (rank : 109)	NC score	0.029950 (rank : 80)
Query Neighborhood Hits	130	Target Neighborhood Hits	440	Shared Neighborhood Hits	21
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

SSRP1_MOUSE
θ value	6.88961 (rank : 110)	NC score	0.020484 (rank : 98)
Query Neighborhood Hits	130	Target Neighborhood Hits	193	Shared Neighborhood Hits	12
SwissProt Accessions	Q08943, Q3U9Z2, Q3UJ75, Q4V9U4, Q8CGA6	Gene names	Ssrp1
Domain Architecture
Description	FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (Structure-specific recognition protein 1) (Recombination signal sequence recognition protein 1) (T160).

TNR1B_MOUSE
θ value	6.88961 (rank : 111)	NC score	0.014497 (rank : 113)
Query Neighborhood Hits	130	Target Neighborhood Hits	123	Shared Neighborhood Hits	2
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

ZN335_HUMAN
θ value	6.88961 (rank : 112)	NC score	0.010693 (rank : 124)
Query Neighborhood Hits	130	Target Neighborhood Hits	973	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H4Z2, Q9H684	Gene names	ZNF335
Domain Architecture	No domain graphic available
Description	Zinc finger protein 335.

ZN462_HUMAN
θ value	6.88961 (rank : 113)	NC score	0.013423 (rank : 118)
Query Neighborhood Hits	130	Target Neighborhood Hits	740	Shared Neighborhood Hits	24
SwissProt Accessions	Q96JM2, Q8N408	Gene names	ZNF462, KIAA1803
Domain Architecture	No domain graphic available
Description	Zinc finger protein 462.

ANK3_HUMAN
θ value	8.99809 (rank : 114)	NC score	0.014363 (rank : 114)
Query Neighborhood Hits	130	Target Neighborhood Hits	853	Shared Neighborhood Hits	29
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

CAF1A_HUMAN
θ value	8.99809 (rank : 115)	NC score	0.036498 (rank : 64)
Query Neighborhood Hits	130	Target Neighborhood Hits	750	Shared Neighborhood Hits	34
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CAF1A_MOUSE
θ value	8.99809 (rank : 116)	NC score	0.036416 (rank : 65)
Query Neighborhood Hits	130	Target Neighborhood Hits	736	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CCNT1_MOUSE
θ value	8.99809 (rank : 117)	NC score	0.013968 (rank : 115)
Query Neighborhood Hits	130	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QWV9, Q9Z0U7	Gene names	Ccnt1
Domain Architecture
Description	Cyclin-T1 (CycT1) (Cyclin-T).

GEMI4_HUMAN
θ value	8.99809 (rank : 118)	NC score	0.023794 (rank : 94)
Query Neighborhood Hits	130	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	P57678, Q9NZS7, Q9UG32, Q9Y4Q2	Gene names	GEMIN4
Domain Architecture	No domain graphic available
Description	Component of gems 4 (Gemin-4) (p97).

GON4L_HUMAN
θ value	8.99809 (rank : 119)	NC score	0.024305 (rank : 91)
Query Neighborhood Hits	130	Target Neighborhood Hits	555	Shared Neighborhood Hits	25
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

HAOX2_MOUSE
θ value	8.99809 (rank : 120)	NC score	0.016118 (rank : 108)
Query Neighborhood Hits	130	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NYQ2, Q9JHS7, Q9JI00	Gene names	Hao2, Hao3, Haox2
Domain Architecture
Description	Hydroxyacid oxidase 2 (EC 1.1.3.15) (HAOX2) ((S)-2-hydroxy-acid oxidase, peroxisomal) (Medium chain alpha-hydroxy acid oxidase) (Medium-chain L-2-hydroxy acid oxidase).

IF2P_HUMAN
θ value	8.99809 (rank : 121)	NC score	0.039457 (rank : 51)
Query Neighborhood Hits	130	Target Neighborhood Hits	889	Shared Neighborhood Hits	39
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

PHC3_MOUSE
θ value	8.99809 (rank : 122)	NC score	0.016150 (rank : 107)
Query Neighborhood Hits	130	Target Neighborhood Hits	194	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CHP6, Q3TLV5	Gene names	Phc3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3.

RAD50_HUMAN
θ value	8.99809 (rank : 123)	NC score	0.042722 (rank : 45)
Query Neighborhood Hits	130	Target Neighborhood Hits	1317	Shared Neighborhood Hits	51
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

REQU_HUMAN
θ value	8.99809 (rank : 124)	NC score	0.024872 (rank : 87)
Query Neighborhood Hits	130	Target Neighborhood Hits	523	Shared Neighborhood Hits	13
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

RERE_HUMAN
θ value	8.99809 (rank : 125)	NC score	0.034430 (rank : 69)
Query Neighborhood Hits	130	Target Neighborhood Hits	779	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RGNEF_MOUSE
θ value	8.99809 (rank : 126)	NC score	0.035442 (rank : 67)
Query Neighborhood Hits	130	Target Neighborhood Hits	641	Shared Neighborhood Hits	33
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

SENP7_HUMAN
θ value	8.99809 (rank : 127)	NC score	0.036798 (rank : 62)
Query Neighborhood Hits	130	Target Neighborhood Hits	97	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BQF6, Q96PS5, Q9C0F6, Q9HBT5	Gene names	SENP7, KIAA1707, SSP2, SUSP2
Domain Architecture
Description	Sentrin-specific protease 7 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP7) (SUMO-1-specific protease 2).

STK10_HUMAN
θ value	8.99809 (rank : 128)	NC score	0.023981 (rank : 93)
Query Neighborhood Hits	130	Target Neighborhood Hits	1921	Shared Neighborhood Hits	54
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

ZN227_HUMAN
θ value	8.99809 (rank : 129)	NC score	0.007946 (rank : 132)
Query Neighborhood Hits	130	Target Neighborhood Hits	781	Shared Neighborhood Hits	21
SwissProt Accessions	Q86WZ6	Gene names	ZNF227
Domain Architecture	No domain graphic available
Description	Zinc finger protein 227.

ZN646_HUMAN
θ value	8.99809 (rank : 130)	NC score	0.010424 (rank : 127)
Query Neighborhood Hits	130	Target Neighborhood Hits	813	Shared Neighborhood Hits	25
SwissProt Accessions	O15015	Gene names	ZNF646, KIAA0296
Domain Architecture	No domain graphic available
Description	Zinc finger protein 646.

HOOK2_MOUSE
θ value	θ > 10 (rank : 131)	NC score	0.050430 (rank : 22)
Query Neighborhood Hits	130	Target Neighborhood Hits	736	Shared Neighborhood Hits	35
SwissProt Accessions	Q7TMK6, Q8BY47, Q8R347, Q8VCN4, Q99LU2	Gene names	Hook2
Domain Architecture
Description	Hook homolog 2.

HOOK3_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.051493 (rank : 21)
Query Neighborhood Hits	130	Target Neighborhood Hits	1070	Shared Neighborhood Hits	43
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

HOOK3_MOUSE
θ value	θ > 10 (rank : 133)	NC score	0.051879 (rank : 20)
Query Neighborhood Hits	130	Target Neighborhood Hits	1007	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

Hits sorted by NC score

CB010_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	130	Target Neighborhood Hits	130	Shared Neighborhood Hits	130
SwissProt Accessions	Q7Z570, Q6ZN26	Gene names	C2orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf10.

GPTC8_HUMAN
NC score	0.307048 (rank : 2)	θ value	1.42992e-13 (rank : 2)
Query Neighborhood Hits	130	Target Neighborhood Hits	366	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

DPOLQ_HUMAN
NC score	0.112022 (rank : 3)	θ value	0.0148317 (rank : 5)
Query Neighborhood Hits	130	Target Neighborhood Hits	67	Shared Neighborhood Hits	5
SwissProt Accessions	O75417, O95160	Gene names	POLQ, POLH
Domain Architecture
Description	DNA polymerase theta (EC 2.7.7.7) (DNA polymerase eta).

CA026_HUMAN
NC score	0.102043 (rank : 4)	θ value	0.279714 (rank : 12)
Query Neighborhood Hits	130	Target Neighborhood Hits	87	Shared Neighborhood Hits	12
SwissProt Accessions	Q5T5J6, Q8NEK9, Q9BZQ7, Q9NXQ0	Gene names	C1orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf26.

CA026_MOUSE
NC score	0.095814 (rank : 5)	θ value	0.279714 (rank : 13)
Query Neighborhood Hits	130	Target Neighborhood Hits	100	Shared Neighborhood Hits	10
SwissProt Accessions	Q9DBQ9, Q6PAN2, Q7TMQ6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf26 homolog.

YLPM1_MOUSE
NC score	0.086039 (rank : 6)	θ value	0.0252991 (rank : 6)
Query Neighborhood Hits	130	Target Neighborhood Hits	505	Shared Neighborhood Hits	14
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

HOOK1_MOUSE
NC score	0.077907 (rank : 7)	θ value	0.00509761 (rank : 3)
Query Neighborhood Hits	130	Target Neighborhood Hits	910	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

HOOK1_HUMAN
NC score	0.075078 (rank : 8)	θ value	0.0330416 (rank : 8)
Query Neighborhood Hits	130	Target Neighborhood Hits	942	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

ATRX_HUMAN
NC score	0.072666 (rank : 9)	θ value	0.0330416 (rank : 7)
Query Neighborhood Hits	130	Target Neighborhood Hits	842	Shared Neighborhood Hits	45
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

RBBP8_HUMAN
NC score	0.069207 (rank : 10)	θ value	1.81305 (rank : 41)
Query Neighborhood Hits	130	Target Neighborhood Hits	476	Shared Neighborhood Hits	42
SwissProt Accessions	Q99708, O75371	Gene names	RBBP8, CTIP
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 8 (RBBP-8) (CtBP-interacting protein) (CtIP) (Retinoblastoma-interacting protein and myosin-like) (RIM).

ZN622_MOUSE
NC score	0.067489 (rank : 11)	θ value	1.38821 (rank : 34)
Query Neighborhood Hits	130	Target Neighborhood Hits	28	Shared Neighborhood Hits	6
SwissProt Accessions	Q91VY9	Gene names	Znf622, D15Ertd806e, Zfp622
Domain Architecture	No domain graphic available
Description	Zinc finger protein 622.

CENPU_HUMAN
NC score	0.060266 (rank : 12)	θ value	1.81305 (rank : 36)
Query Neighborhood Hits	130	Target Neighborhood Hits	289	Shared Neighborhood Hits	23
SwissProt Accessions	Q71F23, Q32Q71, Q9H5G1	Gene names	MLF1IP, CENPU, ICEN24, KLIP1
Domain Architecture	No domain graphic available
Description	Centromere protein U (CENP-U) (CENP-U(50)) (CENP-50) (Interphase centromere complex protein 24) (MLF1-interacting protein) (KSHV latent nuclear antigen-interacting protein 1).

ATN1_HUMAN
NC score	0.058575 (rank : 13)	θ value	0.813845 (rank : 20)
Query Neighborhood Hits	130	Target Neighborhood Hits	676	Shared Neighborhood Hits	21
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

ZN622_HUMAN
NC score	0.058545 (rank : 14)	θ value	3.0926 (rank : 62)
Query Neighborhood Hits	130	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	Q969S3	Gene names	ZNF622, ZPR9
Domain Architecture	No domain graphic available
Description	Zinc finger protein 622 (Zinc finger-like protein 9).

ATRX_MOUSE
NC score	0.055357 (rank : 15)	θ value	2.36792 (rank : 42)
Query Neighborhood Hits	130	Target Neighborhood Hits	682	Shared Neighborhood Hits	37
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

MLL3_MOUSE
NC score	0.055215 (rank : 16)	θ value	0.0563607 (rank : 9)
Query Neighborhood Hits	130	Target Neighborhood Hits	1399	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

PIAS1_MOUSE
NC score	0.054857 (rank : 17)	θ value	0.163984 (rank : 11)
Query Neighborhood Hits	130	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	O88907, Q8C6H5	Gene names	Pias1, Ddxbp1
Domain Architecture
Description	Protein inhibitor of activated STAT protein 1 (DEAD/H box-binding protein 1).

FA76B_HUMAN
NC score	0.051997 (rank : 18)	θ value	1.81305 (rank : 37)
Query Neighborhood Hits	130	Target Neighborhood Hits	184	Shared Neighborhood Hits	16
SwissProt Accessions	Q5HYJ3, Q6PIU3, Q8TC53	Gene names	FAM76B
Domain Architecture	No domain graphic available
Description	Protein FAM76B.

PO121_MOUSE
NC score	0.051994 (rank : 19)	θ value	0.62314 (rank : 17)
Query Neighborhood Hits	130	Target Neighborhood Hits	345	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

HOOK3_MOUSE
NC score	0.051879 (rank : 20)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	130	Target Neighborhood Hits	1007	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

HOOK3_HUMAN
NC score	0.051493 (rank : 21)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	130	Target Neighborhood Hits	1070	Shared Neighborhood Hits	43
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

HOOK2_MOUSE
NC score	0.050430 (rank : 22)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	130	Target Neighborhood Hits	736	Shared Neighborhood Hits	35
SwissProt Accessions	Q7TMK6, Q8BY47, Q8R347, Q8VCN4, Q99LU2	Gene names	Hook2
Domain Architecture
Description	Hook homolog 2.

RAI14_HUMAN
NC score	0.050373 (rank : 23)	θ value	0.00665767 (rank : 4)
Query Neighborhood Hits	130	Target Neighborhood Hits	1367	Shared Neighborhood Hits	46
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

EDEM3_HUMAN
NC score	0.049939 (rank : 24)	θ value	0.279714 (rank : 14)
Query Neighborhood Hits	130	Target Neighborhood Hits	92	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BZQ6, Q5TEZ0, Q9HCW1, Q9UFV7	Gene names	EDEM3, C1orf22
Domain Architecture
Description	ER degradation-enhancing alpha-mannosidase-like 3.

NAF1_HUMAN
NC score	0.049777 (rank : 25)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	130	Target Neighborhood Hits	937	Shared Neighborhood Hits	41
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

NAF1_MOUSE
NC score	0.048218 (rank : 26)	θ value	4.03905 (rank : 66)
Query Neighborhood Hits	130	Target Neighborhood Hits	852	Shared Neighborhood Hits	42
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

CLSPN_HUMAN
NC score	0.048144 (rank : 27)	θ value	1.38821 (rank : 29)
Query Neighborhood Hits	130	Target Neighborhood Hits	433	Shared Neighborhood Hits	28
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

AUTS2_HUMAN
NC score	0.047475 (rank : 28)	θ value	1.81305 (rank : 35)
Query Neighborhood Hits	130	Target Neighborhood Hits	342	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

CE025_HUMAN
NC score	0.047433 (rank : 29)	θ value	3.0926 (rank : 54)
Query Neighborhood Hits	130	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NDZ2, Q6NXN8, Q6ZTU4, Q8IZ15	Gene names	C5orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C5orf25.

KCTD3_HUMAN
NC score	0.047280 (rank : 30)	θ value	0.365318 (rank : 15)
Query Neighborhood Hits	130	Target Neighborhood Hits	90	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y597, Q49AG7, Q504Q9, Q6PJN6, Q8ND58, Q8NDJ0, Q8WX16	Gene names	KCTD3
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD3 (NY-REN-45 antigen).

CCD46_HUMAN
NC score	0.047191 (rank : 31)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	130	Target Neighborhood Hits	1430	Shared Neighborhood Hits	52
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

CCD46_MOUSE
NC score	0.046867 (rank : 32)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	130	Target Neighborhood Hits	1405	Shared Neighborhood Hits	52
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

CF152_MOUSE
NC score	0.046560 (rank : 33)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	130	Target Neighborhood Hits	597	Shared Neighborhood Hits	34
SwissProt Accessions	Q80ST9, Q9CYM9, Q9D5J9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf152 homolog.

LUZP1_HUMAN
NC score	0.045944 (rank : 34)	θ value	3.0926 (rank : 55)
Query Neighborhood Hits	130	Target Neighborhood Hits	739	Shared Neighborhood Hits	34
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

PIAS1_HUMAN
NC score	0.045735 (rank : 35)	θ value	1.38821 (rank : 30)
Query Neighborhood Hits	130	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	O75925, Q99751, Q9UN02	Gene names	PIAS1, DDXBP1
Domain Architecture
Description	Protein inhibitor of activated STAT protein 1 (Gu-binding protein) (GBP) (RNA helicase II-binding protein) (DEAD/H box-binding protein 1).

EP15_MOUSE
NC score	0.045082 (rank : 36)	θ value	0.813845 (rank : 22)
Query Neighborhood Hits	130	Target Neighborhood Hits	820	Shared Neighborhood Hits	31
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

FA76B_MOUSE
NC score	0.045055 (rank : 37)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	130	Target Neighborhood Hits	181	Shared Neighborhood Hits	18
SwissProt Accessions	Q80XP8, Q3UMA6, Q80YR1, Q8CI69	Gene names	Fam76b
Domain Architecture	No domain graphic available
Description	Protein FAM76B.

S2A4R_HUMAN
NC score	0.045054 (rank : 38)	θ value	4.03905 (rank : 69)
Query Neighborhood Hits	130	Target Neighborhood Hits	54	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NR83, Q6F6I6, Q6F6I7, Q6GTK5, Q8TAH5, Q8WVW7, Q96QD3, Q9BV85	Gene names	SLC2A4RG, HDBP1
Domain Architecture	No domain graphic available
Description	SLC2A4 regulator (GLUT4 enhancer factor) (GEF) (Huntington disease gene regulatory region-binding protein 1) (HDBP-1).

CENPF_HUMAN
NC score	0.044697 (rank : 39)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	130	Target Neighborhood Hits	1932	Shared Neighborhood Hits	63
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

SAFB2_MOUSE
NC score	0.043664 (rank : 40)	θ value	3.0926 (rank : 57)
Query Neighborhood Hits	130	Target Neighborhood Hits	581	Shared Neighborhood Hits	33
SwissProt Accessions	Q80YR5, Q8K153	Gene names	Safb2
Domain Architecture
Description	Scaffold attachment factor B2.

GOGB1_HUMAN
NC score	0.043624 (rank : 41)	θ value	6.88961 (rank : 104)
Query Neighborhood Hits	130	Target Neighborhood Hits	2297	Shared Neighborhood Hits	66
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

SAFB2_HUMAN
NC score	0.043131 (rank : 42)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	130	Target Neighborhood Hits	720	Shared Neighborhood Hits	33
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

SGOL2_HUMAN
NC score	0.043035 (rank : 43)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	130	Target Neighborhood Hits	207	Shared Neighborhood Hits	15
SwissProt Accessions	Q562F6, Q53RR9, Q53T20, Q86XY4, Q8IWK2, Q8IZK1, Q8N1Q5, Q96LQ3	Gene names	SGOL2
Domain Architecture	No domain graphic available
Description	Shugoshin-like 2 (Tripin).

CYTSA_MOUSE
NC score	0.042839 (rank : 44)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	130	Target Neighborhood Hits	1104	Shared Neighborhood Hits	43
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

RAD50_HUMAN
NC score	0.042722 (rank : 45)	θ value	8.99809 (rank : 123)
Query Neighborhood Hits	130	Target Neighborhood Hits	1317	Shared Neighborhood Hits	51
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

CYTSA_HUMAN
NC score	0.042044 (rank : 46)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	130	Target Neighborhood Hits	1138	Shared Neighborhood Hits	42
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

CENPE_HUMAN
NC score	0.041952 (rank : 47)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	130	Target Neighborhood Hits	2060	Shared Neighborhood Hits	61
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

GP73_MOUSE
NC score	0.041572 (rank : 48)	θ value	6.88961 (rank : 105)
Query Neighborhood Hits	130	Target Neighborhood Hits	506	Shared Neighborhood Hits	32
SwissProt Accessions	Q91XA2	Gene names	Golph2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

EEA1_HUMAN
NC score	0.040513 (rank : 49)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	130	Target Neighborhood Hits	1796	Shared Neighborhood Hits	56
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

UACA_HUMAN
NC score	0.040453 (rank : 50)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	130	Target Neighborhood Hits	1622	Shared Neighborhood Hits	57
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

IF2P_HUMAN
NC score	0.039457 (rank : 51)	θ value	8.99809 (rank : 121)
Query Neighborhood Hits	130	Target Neighborhood Hits	889	Shared Neighborhood Hits	39
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

CD008_HUMAN
NC score	0.039325 (rank : 52)	θ value	5.27518 (rank : 75)
Query Neighborhood Hits	130	Target Neighborhood Hits	330	Shared Neighborhood Hits	25
SwissProt Accessions	P78312, O43607, P78311, P78313, Q9UEG8	Gene names	C4orf8
Domain Architecture	No domain graphic available
Description	Protein C4orf8 (Protein IT14).

ANKZ1_HUMAN
NC score	0.039252 (rank : 53)	θ value	3.0926 (rank : 50)
Query Neighborhood Hits	130	Target Neighborhood Hits	236	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

ITSN1_HUMAN
NC score	0.039095 (rank : 54)	θ value	2.36792 (rank : 45)
Query Neighborhood Hits	130	Target Neighborhood Hits	1757	Shared Neighborhood Hits	56
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

RIF1_HUMAN
NC score	0.038719 (rank : 55)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	130	Target Neighborhood Hits	320	Shared Neighborhood Hits	25
SwissProt Accessions	Q5UIP0, Q5H9R3, Q5UIP2, Q66YK6, Q6PRU2, Q8TE94, Q99772, Q9H830, Q9H9B9, Q9NVP5, Q9Y4R4	Gene names	RIF1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog).

USH1C_MOUSE
NC score	0.038373 (rank : 56)	θ value	0.813845 (rank : 26)
Query Neighborhood Hits	130	Target Neighborhood Hits	557	Shared Neighborhood Hits	24
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

SON_HUMAN
NC score	0.038054 (rank : 57)	θ value	0.62314 (rank : 18)
Query Neighborhood Hits	130	Target Neighborhood Hits	1568	Shared Neighborhood Hits	36
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

ANR12_HUMAN
NC score	0.038012 (rank : 58)	θ value	1.38821 (rank : 27)
Query Neighborhood Hits	130	Target Neighborhood Hits	1081	Shared Neighborhood Hits	48
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

EEA1_MOUSE
NC score	0.037921 (rank : 59)	θ value	6.88961 (rank : 101)
Query Neighborhood Hits	130	Target Neighborhood Hits	1637	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

RNF17_MOUSE
NC score	0.037701 (rank : 60)	θ value	3.0926 (rank : 56)
Query Neighborhood Hits	130	Target Neighborhood Hits	147	Shared Neighborhood Hits	11
SwissProt Accessions	Q99MV7	Gene names	Rnf17
Domain Architecture
Description	RING finger protein 17.

RERE_MOUSE
NC score	0.036951 (rank : 61)	θ value	6.88961 (rank : 108)
Query Neighborhood Hits	130	Target Neighborhood Hits	785	Shared Neighborhood Hits	21
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

SENP7_HUMAN
NC score	0.036798 (rank : 62)	θ value	8.99809 (rank : 127)
Query Neighborhood Hits	130	Target Neighborhood Hits	97	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BQF6, Q96PS5, Q9C0F6, Q9HBT5	Gene names	SENP7, KIAA1707, SSP2, SUSP2
Domain Architecture
Description	Sentrin-specific protease 7 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP7) (SUMO-1-specific protease 2).

DMP1_HUMAN
NC score	0.036765 (rank : 63)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	130	Target Neighborhood Hits	491	Shared Neighborhood Hits	31
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

CAF1A_HUMAN
NC score	0.036498 (rank : 64)	θ value	8.99809 (rank : 115)
Query Neighborhood Hits	130	Target Neighborhood Hits	750	Shared Neighborhood Hits	34
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CAF1A_MOUSE
NC score	0.036416 (rank : 65)	θ value	8.99809 (rank : 116)
Query Neighborhood Hits	130	Target Neighborhood Hits	736	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

BRCA2_MOUSE
NC score	0.035989 (rank : 66)	θ value	3.0926 (rank : 53)
Query Neighborhood Hits	130	Target Neighborhood Hits	222	Shared Neighborhood Hits	15
SwissProt Accessions	P97929, O35922, P97383	Gene names	Brca2, Fancd1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein homolog (Fanconi anemia group D1 protein homolog).

RGNEF_MOUSE
NC score	0.035442 (rank : 67)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	130	Target Neighborhood Hits	641	Shared Neighborhood Hits	33
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

SOX13_MOUSE
NC score	0.034777 (rank : 68)	θ value	0.813845 (rank : 23)
Query Neighborhood Hits	130	Target Neighborhood Hits	495	Shared Neighborhood Hits	21
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

RERE_HUMAN
NC score	0.034430 (rank : 69)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	130	Target Neighborhood Hits	779	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

SRRM2_HUMAN
NC score	0.034408 (rank : 70)	θ value	1.38821 (rank : 31)
Query Neighborhood Hits	130	Target Neighborhood Hits	1296	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

ARHG2_HUMAN
NC score	0.033982 (rank : 71)	θ value	3.0926 (rank : 51)
Query Neighborhood Hits	130	Target Neighborhood Hits	142	Shared Neighborhood Hits	9
SwissProt Accessions	Q92974, O75142, Q15079	Gene names	ARHGEF2, KIAA0651, LFP40
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (GEF-H1 protein) (Proliferating cell nucleolar antigen p40).

PROX1_MOUSE
NC score	0.033862 (rank : 72)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	130	Target Neighborhood Hits	184	Shared Neighborhood Hits	17
SwissProt Accessions	P48437, O88478, Q3UPV1, Q543D8	Gene names	Prox1
Domain Architecture
Description	Homeobox prospero-like protein PROX1 (PROX 1).

DPF3_HUMAN
NC score	0.032808 (rank : 73)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	130	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q92784, Q9H7Y5	Gene names	DPF3, CERD4
Domain Architecture	No domain graphic available
Description	Zinc-finger protein DPF3 (cer-d4).

ROCK1_MOUSE
NC score	0.031327 (rank : 74)	θ value	0.125558 (rank : 10)
Query Neighborhood Hits	130	Target Neighborhood Hits	2126	Shared Neighborhood Hits	54
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

NUCB2_MOUSE
NC score	0.030975 (rank : 75)	θ value	6.88961 (rank : 107)
Query Neighborhood Hits	130	Target Neighborhood Hits	459	Shared Neighborhood Hits	30
SwissProt Accessions	P81117	Gene names	Nucb2, Nefa
Domain Architecture	No domain graphic available
Description	Nucleobindin-2 precursor (DNA-binding protein NEFA).

TP53B_HUMAN
NC score	0.030651 (rank : 76)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	130	Target Neighborhood Hits	413	Shared Neighborhood Hits	23
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

MYH9_HUMAN
NC score	0.030602 (rank : 77)	θ value	1.81305 (rank : 39)
Query Neighborhood Hits	130	Target Neighborhood Hits	1762	Shared Neighborhood Hits	56
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

ERF_HUMAN
NC score	0.030379 (rank : 78)	θ value	2.36792 (rank : 43)
Query Neighborhood Hits	130	Target Neighborhood Hits	162	Shared Neighborhood Hits	6
SwissProt Accessions	P50548, Q9UPI7	Gene names	ERF
Domain Architecture
Description	ETS domain-containing transcription factor ERF (Ets2 repressor factor).

ERF_MOUSE
NC score	0.030255 (rank : 79)	θ value	2.36792 (rank : 44)
Query Neighborhood Hits	130	Target Neighborhood Hits	160	Shared Neighborhood Hits	6
SwissProt Accessions	P70459	Gene names	Erf
Domain Architecture
Description	ETS domain-containing transcription factor ERF.

RN168_MOUSE
NC score	0.029950 (rank : 80)	θ value	6.88961 (rank : 109)
Query Neighborhood Hits	130	Target Neighborhood Hits	440	Shared Neighborhood Hits	21
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

ARHG2_MOUSE
NC score	0.028978 (rank : 81)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	130	Target Neighborhood Hits	120	Shared Neighborhood Hits	9
SwissProt Accessions	Q60875, O09115	Gene names	Arhgef2, Lbcl1, Lfc
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (Lymphoid blast crisis- like 1) (LBC'S first cousin) (Oncogene LFC) (RHOBIN).

STK10_MOUSE
NC score	0.028116 (rank : 82)	θ value	1.38821 (rank : 32)
Query Neighborhood Hits	130	Target Neighborhood Hits	2132	Shared Neighborhood Hits	57
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

BAG3_HUMAN
NC score	0.027958 (rank : 83)	θ value	3.0926 (rank : 52)
Query Neighborhood Hits	130	Target Neighborhood Hits	314	Shared Neighborhood Hits	9
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

REQU_MOUSE
NC score	0.027458 (rank : 84)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	130	Target Neighborhood Hits	519	Shared Neighborhood Hits	13
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

CBPB2_HUMAN
NC score	0.027329 (rank : 85)	θ value	0.813845 (rank : 21)
Query Neighborhood Hits	130	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q96IY4, Q15114, Q5T9K1, Q5T9K2, Q9P2Y6	Gene names	CPB2
Domain Architecture	No domain graphic available
Description	Carboxypeptidase B2 precursor (EC 3.4.17.20) (Carboxypeptidase U) (CPU) (Thrombin-activable fibrinolysis inhibitor) (TAFI) (Plasma carboxypeptidase B) (pCPB).

PKD1_HUMAN
NC score	0.025129 (rank : 86)	θ value	1.81305 (rank : 40)
Query Neighborhood Hits	130	Target Neighborhood Hits	387	Shared Neighborhood Hits	4
SwissProt Accessions	P98161, Q15140, Q15141	Gene names	PKD1
Domain Architecture
Description	Polycystin-1 precursor (Autosomal dominant polycystic kidney disease protein 1).

REQU_HUMAN
NC score	0.024872 (rank : 87)	θ value	8.99809 (rank : 124)
Query Neighborhood Hits	130	Target Neighborhood Hits	523	Shared Neighborhood Hits	13
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

SLK_HUMAN
NC score	0.024840 (rank : 88)	θ value	2.36792 (rank : 49)
Query Neighborhood Hits	130	Target Neighborhood Hits	1775	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

TLK2_MOUSE
NC score	0.024680 (rank : 89)	θ value	0.813845 (rank : 25)
Query Neighborhood Hits	130	Target Neighborhood Hits	1088	Shared Neighborhood Hits	33
SwissProt Accessions	O55047, Q9D5Y5	Gene names	Tlk2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2).

CTRO_HUMAN
NC score	0.024494 (rank : 90)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	130	Target Neighborhood Hits	2092	Shared Neighborhood Hits	50
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

GON4L_HUMAN
NC score	0.024305 (rank : 91)	θ value	8.99809 (rank : 119)
Query Neighborhood Hits	130	Target Neighborhood Hits	555	Shared Neighborhood Hits	25
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

SLK_MOUSE
NC score	0.023995 (rank : 92)	θ value	3.0926 (rank : 58)
Query Neighborhood Hits	130	Target Neighborhood Hits	1798	Shared Neighborhood Hits	56
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

STK10_HUMAN
NC score	0.023981 (rank : 93)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	130	Target Neighborhood Hits	1921	Shared Neighborhood Hits	54
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

GEMI4_HUMAN
NC score	0.023794 (rank : 94)	θ value	8.99809 (rank : 118)
Query Neighborhood Hits	130	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	P57678, Q9NZS7, Q9UG32, Q9Y4Q2	Gene names	GEMIN4
Domain Architecture	No domain graphic available
Description	Component of gems 4 (Gemin-4) (p97).

TLK2_HUMAN
NC score	0.023561 (rank : 95)	θ value	0.813845 (rank : 24)
Query Neighborhood Hits	130	Target Neighborhood Hits	1044	Shared Neighborhood Hits	30
SwissProt Accessions	Q86UE8, Q9UKI7, Q9Y4F7	Gene names	TLK2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2) (PKU-alpha).

WNK4_MOUSE
NC score	0.022999 (rank : 96)	θ value	0.62314 (rank : 19)
Query Neighborhood Hits	130	Target Neighborhood Hits	961	Shared Neighborhood Hits	19
SwissProt Accessions	Q80UE6, Q4VAC1, Q80XB5, Q80XN2, Q8R0N0, Q8R340	Gene names	Wnk4, Prkwnk4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

UTY_MOUSE
NC score	0.021414 (rank : 97)	θ value	5.27518 (rank : 92)
Query Neighborhood Hits	130	Target Neighborhood Hits	64	Shared Neighborhood Hits	3
SwissProt Accessions	P79457, O97979	Gene names	Uty
Domain Architecture
Description	Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein (Ubiquitously transcribed TPR protein ON the Y chromosome) (Male- specific histocompatibility antigen H-YDB).

SSRP1_MOUSE
NC score	0.020484 (rank : 98)	θ value	6.88961 (rank : 110)
Query Neighborhood Hits	130	Target Neighborhood Hits	193	Shared Neighborhood Hits	12
SwissProt Accessions	Q08943, Q3U9Z2, Q3UJ75, Q4V9U4, Q8CGA6	Gene names	Ssrp1
Domain Architecture
Description	FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (Structure-specific recognition protein 1) (Recombination signal sequence recognition protein 1) (T160).

WNK2_HUMAN
NC score	0.020403 (rank : 99)	θ value	3.0926 (rank : 59)
Query Neighborhood Hits	130	Target Neighborhood Hits	1407	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

RLF_HUMAN
NC score	0.018230 (rank : 100)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	130	Target Neighborhood Hits	775	Shared Neighborhood Hits	23
SwissProt Accessions	Q13129, Q9NU60	Gene names	RLF
Domain Architecture	No domain graphic available
Description	Zinc finger protein Rlf (Rearranged L-myc fusion gene protein) (Zn-15- related protein).

TRI45_MOUSE
NC score	0.018033 (rank : 101)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	130	Target Neighborhood Hits	155	Shared Neighborhood Hits	9
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

MTF1_HUMAN
NC score	0.017682 (rank : 102)	θ value	0.365318 (rank : 16)
Query Neighborhood Hits	130	Target Neighborhood Hits	814	Shared Neighborhood Hits	19
SwissProt Accessions	Q14872, Q96CB1	Gene names	MTF1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

SUHW4_HUMAN
NC score	0.017649 (rank : 103)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	130	Target Neighborhood Hits	860	Shared Neighborhood Hits	33
SwissProt Accessions	Q6N043, Q6MZM6, Q6N085, Q9H0U5, Q9HCI8, Q9NXS0	Gene names	SUHW4, KIAA1584
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

DNMBP_HUMAN
NC score	0.017308 (rank : 104)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	130	Target Neighborhood Hits	413	Shared Neighborhood Hits	14
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

KLF11_MOUSE
NC score	0.016428 (rank : 105)	θ value	2.36792 (rank : 47)
Query Neighborhood Hits	130	Target Neighborhood Hits	714	Shared Neighborhood Hits	18
SwissProt Accessions	Q9EPF4	Gene names	Klf11, Tieg2
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 11 (Transforming growth factor-beta-inducible early growth response protein 2) (TGFB-inducible early growth response protein 2) (TIEG-2).

KLF11_HUMAN
NC score	0.016379 (rank : 106)	θ value	2.36792 (rank : 46)
Query Neighborhood Hits	130	Target Neighborhood Hits	717	Shared Neighborhood Hits	18
SwissProt Accessions	O14901	Gene names	KLF11, FKLF, TIEG2
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 11 (Transforming growth factor-beta-inducible early growth response protein 2) (TGFB-inducible early growth response protein 2) (TIEG-2).

PHC3_MOUSE
NC score	0.016150 (rank : 107)	θ value	8.99809 (rank : 122)
Query Neighborhood Hits	130	Target Neighborhood Hits	194	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CHP6, Q3TLV5	Gene names	Phc3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3.

HAOX2_MOUSE
NC score	0.016118 (rank : 108)	θ value	8.99809 (rank : 120)
Query Neighborhood Hits	130	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NYQ2, Q9JHS7, Q9JI00	Gene names	Hao2, Hao3, Haox2
Domain Architecture
Description	Hydroxyacid oxidase 2 (EC 1.1.3.15) (HAOX2) ((S)-2-hydroxy-acid oxidase, peroxisomal) (Medium chain alpha-hydroxy acid oxidase) (Medium-chain L-2-hydroxy acid oxidase).

ZN131_HUMAN
NC score	0.015443 (rank : 109)	θ value	3.0926 (rank : 60)
Query Neighborhood Hits	130	Target Neighborhood Hits	833	Shared Neighborhood Hits	22
SwissProt Accessions	P52739, Q6PIF0	Gene names	ZNF131
Domain Architecture	No domain graphic available
Description	Zinc finger protein 131.

ZN131_MOUSE
NC score	0.015247 (rank : 110)	θ value	3.0926 (rank : 61)
Query Neighborhood Hits	130	Target Neighborhood Hits	833	Shared Neighborhood Hits	22
SwissProt Accessions	Q8K3J5, Q3UYZ4, Q80UU7, Q8C8D0, Q9D042	Gene names	Znf131, Zfp131
Domain Architecture	No domain graphic available
Description	Zinc finger protein 131.

ATR_MOUSE
NC score	0.014994 (rank : 111)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	130	Target Neighborhood Hits	63	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JKK8	Gene names	Atr
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein).

MTF1_MOUSE
NC score	0.014896 (rank : 112)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	130	Target Neighborhood Hits	785	Shared Neighborhood Hits	20
SwissProt Accessions	Q07243	Gene names	Mtf1, Mtf-1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

TNR1B_MOUSE
NC score	0.014497 (rank : 113)	θ value	6.88961 (rank : 111)
Query Neighborhood Hits	130	Target Neighborhood Hits	123	Shared Neighborhood Hits	2
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

ANK3_HUMAN
NC score	0.014363 (rank : 114)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	130	Target Neighborhood Hits	853	Shared Neighborhood Hits	29
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

CCNT1_MOUSE
NC score	0.013968 (rank : 115)	θ value	8.99809 (rank : 117)
Query Neighborhood Hits	130	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QWV9, Q9Z0U7	Gene names	Ccnt1
Domain Architecture
Description	Cyclin-T1 (CycT1) (Cyclin-T).

PZP_HUMAN
NC score	0.013892 (rank : 116)	θ value	5.27518 (rank : 84)
Query Neighborhood Hits	130	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	P20742, Q15273	Gene names	PZP
Domain Architecture
Description	Pregnancy zone protein precursor.

UBP47_MOUSE
NC score	0.013550 (rank : 117)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	130	Target Neighborhood Hits	135	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

ZN462_HUMAN
NC score	0.013423 (rank : 118)	θ value	6.88961 (rank : 113)
Query Neighborhood Hits	130	Target Neighborhood Hits	740	Shared Neighborhood Hits	24
SwissProt Accessions	Q96JM2, Q8N408	Gene names	ZNF462, KIAA1803
Domain Architecture	No domain graphic available
Description	Zinc finger protein 462.

P3C2G_HUMAN
NC score	0.013271 (rank : 119)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	130	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	O75747	Gene names	PIK3C2G
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).

FGF1_MOUSE
NC score	0.012117 (rank : 120)	θ value	6.88961 (rank : 102)
Query Neighborhood Hits	130	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	P61148, P10935	Gene names	Fgf1, Fgf-1, Fgfa
Domain Architecture
Description	Heparin-binding growth factor 1 precursor (HBGF-1) (Acidic fibroblast growth factor) (aFGF).

PRD16_HUMAN
NC score	0.012025 (rank : 121)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	130	Target Neighborhood Hits	832	Shared Neighborhood Hits	25
SwissProt Accessions	Q9HAZ2, Q8WYJ9, Q9C0I8	Gene names	PRDM16, KIAA1675, MEL1, PFM13
Domain Architecture
Description	PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1).

PRD10_HUMAN
NC score	0.011779 (rank : 122)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	130	Target Neighborhood Hits	769	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NQV6, Q9ULI9	Gene names	PRDM10, KIAA1231, PFM7
Domain Architecture	No domain graphic available
Description	PR domain zinc finger protein 10 (PR domain-containing protein 10).

ZBT11_HUMAN
NC score	0.011044 (rank : 123)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	130	Target Neighborhood Hits	873	Shared Neighborhood Hits	22
SwissProt Accessions	O95625	Gene names	ZBTB11
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 11.

ZN335_HUMAN
NC score	0.010693 (rank : 124)	θ value	6.88961 (rank : 112)
Query Neighborhood Hits	130	Target Neighborhood Hits	973	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H4Z2, Q9H684	Gene names	ZNF335
Domain Architecture	No domain graphic available
Description	Zinc finger protein 335.

PCD15_HUMAN
NC score	0.010680 (rank : 125)	θ value	2.36792 (rank : 48)
Query Neighborhood Hits	130	Target Neighborhood Hits	289	Shared Neighborhood Hits	5
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

HXA4_HUMAN
NC score	0.010659 (rank : 126)	θ value	1.81305 (rank : 38)
Query Neighborhood Hits	130	Target Neighborhood Hits	370	Shared Neighborhood Hits	4
SwissProt Accessions	Q00056, O43366	Gene names	HOXA4, HOX1D
Domain Architecture
Description	Homeobox protein Hox-A4 (Hox-1D) (Hox-1.4).

ZN646_HUMAN
NC score	0.010424 (rank : 127)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	130	Target Neighborhood Hits	813	Shared Neighborhood Hits	25
SwissProt Accessions	O15015	Gene names	ZNF646, KIAA0296
Domain Architecture	No domain graphic available
Description	Zinc finger protein 646.

ZN611_HUMAN
NC score	0.009919 (rank : 128)	θ value	1.38821 (rank : 33)
Query Neighborhood Hits	130	Target Neighborhood Hits	769	Shared Neighborhood Hits	21
SwissProt Accessions	Q8N823, Q69YG9	Gene names	ZNF611
Domain Architecture	No domain graphic available
Description	Zinc finger protein 611.

ZN701_HUMAN
NC score	0.009505 (rank : 129)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	130	Target Neighborhood Hits	747	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NV72, Q66K42	Gene names	ZNF701
Domain Architecture	No domain graphic available
Description	Zinc finger protein 701.

TLR5_HUMAN
NC score	0.008532 (rank : 130)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	130	Target Neighborhood Hits	288	Shared Neighborhood Hits	3
SwissProt Accessions	O60602, O15456	Gene names	TLR5, TIL3
Domain Architecture
Description	Toll-like receptor 5 precursor (Toll/interleukin-1 receptor-like protein 3).

NKX61_MOUSE
NC score	0.008313 (rank : 131)	θ value	6.88961 (rank : 106)
Query Neighborhood Hits	130	Target Neighborhood Hits	439	Shared Neighborhood Hits	6
SwissProt Accessions	Q99MA9, Q9ERQ7	Gene names	Nkx6-1, Nkx6.1, Nkx6a
Domain Architecture
Description	Homeobox protein Nkx-6.1.

ZN227_HUMAN
NC score	0.007946 (rank : 132)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	130	Target Neighborhood Hits	781	Shared Neighborhood Hits	21
SwissProt Accessions	Q86WZ6	Gene names	ZNF227
Domain Architecture	No domain graphic available
Description	Zinc finger protein 227.

FOXJ3_HUMAN
NC score	0.007729 (rank : 133)	θ value	6.88961 (rank : 103)
Query Neighborhood Hits	130	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UPW0, Q9NSS7	Gene names	FOXJ3, KIAA1041
Domain Architecture
Description	Forkhead box protein J3.