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Network neighborhood for query Sequence : ZFY28_HUMAN

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ZFY28_HUMAN
SwissProt Accessions	Q9HCC9	Gene names	ZFYVE28, KIAA1643
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 28.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ZFY28_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	152	Target Neighborhood Hits	152	Shared Neighborhood Hits	152
SwissProt Accessions	Q9HCC9	Gene names	ZFYVE28, KIAA1643
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 28.

ZFY21_MOUSE
θ value	3.40345e-15 (rank : 2)	NC score	0.813250 (rank : 2)
Query Neighborhood Hits	152	Target Neighborhood Hits	72	Shared Neighborhood Hits	57
SwissProt Accessions	Q8VCM3, Q9D1E2	Gene names	Zfyve21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

ZFY21_HUMAN
θ value	4.44505e-15 (rank : 3)	NC score	0.812010 (rank : 3)
Query Neighborhood Hits	152	Target Neighborhood Hits	72	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BQ24, Q86T05, Q96LT1	Gene names	ZFYVE21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

FGD2_HUMAN
θ value	2.20605e-14 (rank : 4)	NC score	0.533203 (rank : 23)
Query Neighborhood Hits	152	Target Neighborhood Hits	151	Shared Neighborhood Hits	50
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

RUFY1_HUMAN
θ value	6.41864e-14 (rank : 5)	NC score	0.446501 (rank : 38)
Query Neighborhood Hits	152	Target Neighborhood Hits	848	Shared Neighborhood Hits	65
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

RUFY1_MOUSE
θ value	6.41864e-14 (rank : 6)	NC score	0.454262 (rank : 34)
Query Neighborhood Hits	152	Target Neighborhood Hits	765	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

HGS_MOUSE
θ value	8.38298e-14 (rank : 7)	NC score	0.605152 (rank : 14)
Query Neighborhood Hits	152	Target Neighborhood Hits	589	Shared Neighborhood Hits	65
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

HGS_HUMAN
θ value	1.42992e-13 (rank : 8)	NC score	0.607053 (rank : 13)
Query Neighborhood Hits	152	Target Neighborhood Hits	517	Shared Neighborhood Hits	58
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

MTMR3_HUMAN
θ value	3.18553e-13 (rank : 9)	NC score	0.447706 (rank : 37)
Query Neighborhood Hits	152	Target Neighborhood Hits	163	Shared Neighborhood Hits	55
SwissProt Accessions	Q13615, Q9NYN5, Q9NYN6, Q9UDX6, Q9UEG3	Gene names	MTMR3, KIAA0371, ZFYVE10
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Zinc finger FYVE domain-containing protein 10).

RUFY2_MOUSE
θ value	3.18553e-13 (rank : 10)	NC score	0.448298 (rank : 36)
Query Neighborhood Hits	152	Target Neighborhood Hits	820	Shared Neighborhood Hits	64
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

FYV1_HUMAN
θ value	4.16044e-13 (rank : 11)	NC score	0.578991 (rank : 15)
Query Neighborhood Hits	152	Target Neighborhood Hits	217	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

FYV1_MOUSE
θ value	4.16044e-13 (rank : 12)	NC score	0.578879 (rank : 16)
Query Neighborhood Hits	152	Target Neighborhood Hits	191	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

FGD6_HUMAN
θ value	9.26847e-13 (rank : 13)	NC score	0.572850 (rank : 17)
Query Neighborhood Hits	152	Target Neighborhood Hits	237	Shared Neighborhood Hits	50
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

FGD2_MOUSE
θ value	3.52202e-12 (rank : 14)	NC score	0.530175 (rank : 24)
Query Neighborhood Hits	152	Target Neighborhood Hits	163	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

RUFY2_HUMAN
θ value	3.52202e-12 (rank : 15)	NC score	0.355309 (rank : 44)
Query Neighborhood Hits	152	Target Neighborhood Hits	1208	Shared Neighborhood Hits	65
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

WDFY3_HUMAN
θ value	6.00763e-12 (rank : 16)	NC score	0.442981 (rank : 40)
Query Neighborhood Hits	152	Target Neighborhood Hits	348	Shared Neighborhood Hits	55
SwissProt Accessions	Q8IZQ1, Q4W5K5, Q6P0Q5, Q8N1T2, Q96BS7, Q96N85, Q9Y2J7	Gene names	WDFY3, KIAA0993
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy).

WDFY3_MOUSE
θ value	6.00763e-12 (rank : 17)	NC score	0.444721 (rank : 39)
Query Neighborhood Hits	152	Target Neighborhood Hits	332	Shared Neighborhood Hits	57
SwissProt Accessions	Q6VNB8, Q8C8H7	Gene names	Wdfy3
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Beach domain, WD repeat and FYVE domain-containing protein 1) (BWF1).

PKHF1_HUMAN
θ value	2.28291e-11 (rank : 18)	NC score	0.731251 (rank : 4)
Query Neighborhood Hits	152	Target Neighborhood Hits	76	Shared Neighborhood Hits	51
SwissProt Accessions	Q96S99, Q96K11, Q9BUB9	Gene names	PLEKHF1, APPD, LAPF, ZFYVE15
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (PH and FYVE domain-containing protein 1) (Phafin-1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains) (Apoptosis-inducing protein) (Zinc finger FYVE domain-containing protein 15).

FGD4_HUMAN
θ value	3.89403e-11 (rank : 19)	NC score	0.499572 (rank : 27)
Query Neighborhood Hits	152	Target Neighborhood Hits	219	Shared Neighborhood Hits	49
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

ZFYV9_HUMAN
θ value	3.89403e-11 (rank : 20)	NC score	0.694392 (rank : 8)
Query Neighborhood Hits	152	Target Neighborhood Hits	134	Shared Neighborhood Hits	55
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

FGD6_MOUSE
θ value	5.08577e-11 (rank : 21)	NC score	0.557471 (rank : 18)
Query Neighborhood Hits	152	Target Neighborhood Hits	282	Shared Neighborhood Hits	53
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

PKHF1_MOUSE
θ value	5.08577e-11 (rank : 22)	NC score	0.723896 (rank : 7)
Query Neighborhood Hits	152	Target Neighborhood Hits	80	Shared Neighborhood Hits	51
SwissProt Accessions	Q3TB82, Q99M16	Gene names	Plekhf1, Lapf
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains).

EEA1_HUMAN
θ value	1.47974e-10 (rank : 23)	NC score	0.238708 (rank : 51)
Query Neighborhood Hits	152	Target Neighborhood Hits	1796	Shared Neighborhood Hits	68
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

ZFYV1_MOUSE
θ value	1.47974e-10 (rank : 24)	NC score	0.647917 (rank : 12)
Query Neighborhood Hits	152	Target Neighborhood Hits	153	Shared Neighborhood Hits	54
SwissProt Accessions	Q810J8	Gene names	Zfyve1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1.

ZFYV1_HUMAN
θ value	1.9326e-10 (rank : 25)	NC score	0.650574 (rank : 11)
Query Neighborhood Hits	152	Target Neighborhood Hits	166	Shared Neighborhood Hits	54
SwissProt Accessions	Q9HBF4, Q8WYX7, Q96K57, Q9BXP9, Q9HCI3	Gene names	ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (Tandem FYVE fingers-1) (SR3).

PKHF2_HUMAN
θ value	2.52405e-10 (rank : 26)	NC score	0.727485 (rank : 6)
Query Neighborhood Hits	152	Target Neighborhood Hits	75	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H8W4	Gene names	PLEKHF2, ZFYVE18
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2) (PH and FYVE domain-containing protein 2) (Phafin-2) (Zinc finger FYVE domain-containing protein 18).

PKHF2_MOUSE
θ value	2.52405e-10 (rank : 27)	NC score	0.728674 (rank : 5)
Query Neighborhood Hits	152	Target Neighborhood Hits	77	Shared Neighborhood Hits	48
SwissProt Accessions	Q91WB4	Gene names	Plekhf2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2).

ZFY16_HUMAN
θ value	2.52405e-10 (rank : 28)	NC score	0.671720 (rank : 10)
Query Neighborhood Hits	152	Target Neighborhood Hits	125	Shared Neighborhood Hits	55
SwissProt Accessions	Q7Z3T8, O15023, Q7LAU7, Q86T69, Q8N5L3, Q8NEK3	Gene names	ZFYVE16, KIAA0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome- associated FYVE domain protein).

ZFY16_MOUSE
θ value	2.52405e-10 (rank : 29)	NC score	0.681424 (rank : 9)
Query Neighborhood Hits	152	Target Neighborhood Hits	108	Shared Neighborhood Hits	54
SwissProt Accessions	Q80U44, Q8BRD2, Q8CG97	Gene names	Zfyve16, Kiaa0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosomal- associated FYVE domain protein).

EEA1_MOUSE
θ value	3.29651e-10 (rank : 30)	NC score	0.257934 (rank : 49)
Query Neighborhood Hits	152	Target Neighborhood Hits	1637	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

ANFY1_HUMAN
θ value	4.30538e-10 (rank : 31)	NC score	0.298239 (rank : 46)
Query Neighborhood Hits	152	Target Neighborhood Hits	480	Shared Neighborhood Hits	53
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANFY1_MOUSE
θ value	5.62301e-10 (rank : 32)	NC score	0.299942 (rank : 45)
Query Neighborhood Hits	152	Target Neighborhood Hits	480	Shared Neighborhood Hits	55
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

FGD4_MOUSE
θ value	1.80886e-08 (rank : 33)	NC score	0.492168 (rank : 28)
Query Neighborhood Hits	152	Target Neighborhood Hits	227	Shared Neighborhood Hits	48
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

WDFY1_HUMAN
θ value	4.0297e-08 (rank : 34)	NC score	0.448592 (rank : 35)
Query Neighborhood Hits	152	Target Neighborhood Hits	305	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IWB7, Q9H9D5, Q9P2B3	Gene names	WDFY1, KIAA1435, WDF1, ZFYVE17
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 1 (WD40- and FYVE domain- containing protein 1) (Phosphoinositide-binding protein 1) (FENS-1) (Zinc finger FYVE domain-containing protein 17).

FGD1_HUMAN
θ value	5.26297e-08 (rank : 35)	NC score	0.484451 (rank : 30)
Query Neighborhood Hits	152	Target Neighborhood Hits	367	Shared Neighborhood Hits	60
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD1_MOUSE
θ value	5.26297e-08 (rank : 36)	NC score	0.484769 (rank : 29)
Query Neighborhood Hits	152	Target Neighborhood Hits	387	Shared Neighborhood Hits	63
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD5_HUMAN
θ value	1.17247e-07 (rank : 37)	NC score	0.553620 (rank : 20)
Query Neighborhood Hits	152	Target Neighborhood Hits	235	Shared Neighborhood Hits	57
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

WDFY2_HUMAN
θ value	1.53129e-07 (rank : 38)	NC score	0.435455 (rank : 42)
Query Neighborhood Hits	152	Target Neighborhood Hits	332	Shared Neighborhood Hits	51
SwissProt Accessions	Q96P53, Q96CS1	Gene names	WDFY2, WDF2, ZFYVE22
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2) (Zinc finger FYVE domain-containing protein 22).

WDFY2_MOUSE
θ value	1.53129e-07 (rank : 39)	NC score	0.438570 (rank : 41)
Query Neighborhood Hits	152	Target Neighborhood Hits	337	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BUB4	Gene names	Wdfy2
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2).

FYCO1_HUMAN
θ value	4.45536e-07 (rank : 40)	NC score	0.282143 (rank : 47)
Query Neighborhood Hits	152	Target Neighborhood Hits	1149	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

ZFY27_HUMAN
θ value	1.29631e-06 (rank : 41)	NC score	0.475461 (rank : 31)
Query Neighborhood Hits	152	Target Neighborhood Hits	64	Shared Neighborhood Hits	44
SwissProt Accessions	Q5T4F4, Q5T4F1, Q5T4F2, Q5T4F3, Q8N1K0, Q8N6D6, Q8NCA0, Q8NDE4, Q96M08	Gene names	ZFYVE27
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 27.

ZFY19_HUMAN
θ value	1.69304e-06 (rank : 42)	NC score	0.548233 (rank : 21)
Query Neighborhood Hits	152	Target Neighborhood Hits	206	Shared Neighborhood Hits	59
SwissProt Accessions	Q96K21, Q86WC2, Q8WU96	Gene names	ZFYVE19, MPFYVE
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19 (MLL partner containing FYVE domain).

ZFY19_MOUSE
θ value	6.43352e-06 (rank : 43)	NC score	0.546095 (rank : 22)
Query Neighborhood Hits	152	Target Neighborhood Hits	143	Shared Neighborhood Hits	56
SwissProt Accessions	Q9DAZ9, Q8VCV7	Gene names	Zfyve19
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19.

ZFY27_MOUSE
θ value	6.43352e-06 (rank : 44)	NC score	0.471241 (rank : 32)
Query Neighborhood Hits	152	Target Neighborhood Hits	53	Shared Neighborhood Hits	44
SwissProt Accessions	Q3TXX3, Q8CFP8	Gene names	Zfyve27
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 27.

FGD5_MOUSE
θ value	1.87187e-05 (rank : 45)	NC score	0.556021 (rank : 19)
Query Neighborhood Hits	152	Target Neighborhood Hits	170	Shared Neighborhood Hits	54
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

RBNS5_HUMAN
θ value	2.44474e-05 (rank : 46)	NC score	0.510022 (rank : 25)
Query Neighborhood Hits	152	Target Neighborhood Hits	242	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H1K0, Q3KP30, Q59EY8, Q8NAQ1	Gene names	ZFYVE20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20) (110 kDa protein).

RBNS5_MOUSE
θ value	2.44474e-05 (rank : 47)	NC score	0.504902 (rank : 26)
Query Neighborhood Hits	152	Target Neighborhood Hits	266	Shared Neighborhood Hits	50
SwissProt Accessions	Q80Y56, Q8K0L6, Q9CTW0	Gene names	Zfyve20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20).

FYCO1_MOUSE
θ value	0.000121331 (rank : 48)	NC score	0.260951 (rank : 48)
Query Neighborhood Hits	152	Target Neighborhood Hits	1059	Shared Neighborhood Hits	63
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

RNF34_MOUSE
θ value	0.00035302 (rank : 49)	NC score	0.240330 (rank : 50)
Query Neighborhood Hits	152	Target Neighborhood Hits	160	Shared Neighborhood Hits	36
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

FGD3_HUMAN
θ value	0.000461057 (rank : 50)	NC score	0.454668 (rank : 33)
Query Neighborhood Hits	152	Target Neighborhood Hits	249	Shared Neighborhood Hits	66
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

RNF34_HUMAN
θ value	0.00175202 (rank : 51)	NC score	0.230104 (rank : 52)
Query Neighborhood Hits	152	Target Neighborhood Hits	153	Shared Neighborhood Hits	34
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

FGD3_MOUSE
θ value	0.0113563 (rank : 52)	NC score	0.407125 (rank : 43)
Query Neighborhood Hits	152	Target Neighborhood Hits	257	Shared Neighborhood Hits	60
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

RFFL_MOUSE
θ value	0.0113563 (rank : 53)	NC score	0.219809 (rank : 53)
Query Neighborhood Hits	152	Target Neighborhood Hits	145	Shared Neighborhood Hits	35
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

RFFL_HUMAN
θ value	0.0193708 (rank : 54)	NC score	0.209064 (rank : 54)
Query Neighborhood Hits	152	Target Neighborhood Hits	175	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

PER3_HUMAN
θ value	0.0252991 (rank : 55)	NC score	0.037682 (rank : 167)
Query Neighborhood Hits	152	Target Neighborhood Hits	479	Shared Neighborhood Hits	14
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

TCF20_HUMAN
θ value	0.125558 (rank : 56)	NC score	0.060780 (rank : 111)
Query Neighborhood Hits	152	Target Neighborhood Hits	323	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

TCF20_MOUSE
θ value	0.125558 (rank : 57)	NC score	0.072419 (rank : 96)
Query Neighborhood Hits	152	Target Neighborhood Hits	396	Shared Neighborhood Hits	15
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

AP1B1_MOUSE
θ value	0.279714 (rank : 58)	NC score	0.027649 (rank : 190)
Query Neighborhood Hits	152	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	O35643, Q922E2	Gene names	Ap1b1, Adtb1
Domain Architecture
Description	AP-1 complex subunit beta-1 (Adapter-related protein complex 1 beta-1 subunit) (Beta-adaptin 1) (Adaptor protein complex AP-1 beta-1 subunit) (Golgi adaptor HA1/AP1 adaptin beta subunit) (Clathrin assembly protein complex 1 beta large chain).

MY18B_HUMAN
θ value	0.279714 (rank : 59)	NC score	0.045283 (rank : 156)
Query Neighborhood Hits	152	Target Neighborhood Hits	1299	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

WDR22_HUMAN
θ value	0.365318 (rank : 60)	NC score	0.031031 (rank : 188)
Query Neighborhood Hits	152	Target Neighborhood Hits	328	Shared Neighborhood Hits	9
SwissProt Accessions	Q96JK2, O60559, Q8N3V3, Q8N3V5	Gene names	WDR22, BCRG2, KIAA1824
Domain Architecture
Description	WD repeat protein 22 (Breakpoint cluster region protein 2) (BCRP2).

ATS14_HUMAN
θ value	0.47712 (rank : 61)	NC score	0.012641 (rank : 216)
Query Neighborhood Hits	152	Target Neighborhood Hits	382	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

ZNF14_HUMAN
θ value	0.47712 (rank : 62)	NC score	0.003340 (rank : 231)
Query Neighborhood Hits	152	Target Neighborhood Hits	760	Shared Neighborhood Hits	21
SwissProt Accessions	P17017, Q9ULZ5	Gene names	ZNF14, GIOT4, KOX6
Domain Architecture
Description	Zinc finger protein 14 (Zinc finger protein KOX6) (Gonadotropin- inducible transcription repressor 4) (GIOT-4).

DC1L2_MOUSE
θ value	0.62314 (rank : 63)	NC score	0.032075 (rank : 182)
Query Neighborhood Hits	152	Target Neighborhood Hits	173	Shared Neighborhood Hits	22
SwissProt Accessions	Q6PDL0	Gene names	Dync1li2, Dncli2, Dnclic2
Domain Architecture	No domain graphic available
Description	Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic).

DTX2_HUMAN
θ value	0.62314 (rank : 64)	NC score	0.035394 (rank : 177)
Query Neighborhood Hits	152	Target Neighborhood Hits	84	Shared Neighborhood Hits	4
SwissProt Accessions	Q86UW9, Q96H69, Q9H890, Q9P200	Gene names	DTX2, KIAA1528
Domain Architecture
Description	Protein deltex-2 (Deltex-2) (Deltex2) (hDTX2).

GP125_HUMAN
θ value	0.62314 (rank : 65)	NC score	0.010412 (rank : 222)
Query Neighborhood Hits	152	Target Neighborhood Hits	327	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IWK6, Q6UXK9, Q86SQ5, Q8TC55	Gene names	GPR125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

TAF6L_MOUSE
θ value	0.62314 (rank : 66)	NC score	0.036232 (rank : 174)
Query Neighborhood Hits	152	Target Neighborhood Hits	146	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R2K4, Q8C5T2	Gene names	Taf6l, Paf65a
Domain Architecture
Description	TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (PCAF-associated factor 65 alpha) (PAF65- alpha).

BSN_MOUSE
θ value	0.813845 (rank : 67)	NC score	0.051426 (rank : 146)
Query Neighborhood Hits	152	Target Neighborhood Hits	2057	Shared Neighborhood Hits	62
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

SOX12_MOUSE
θ value	0.813845 (rank : 68)	NC score	0.013125 (rank : 214)
Query Neighborhood Hits	152	Target Neighborhood Hits	98	Shared Neighborhood Hits	3
SwissProt Accessions	Q04890, P70417, Q6NXL2	Gene names	Sox12, Sox-12
Domain Architecture	No domain graphic available
Description	SOX-12 protein.

ZN302_HUMAN
θ value	0.813845 (rank : 69)	NC score	0.002520 (rank : 234)
Query Neighborhood Hits	152	Target Neighborhood Hits	755	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NR11, Q9BZD8, Q9P0J4	Gene names	ZNF302, ZNF135L, ZNF140L
Domain Architecture
Description	Zinc finger protein 302 (ZNF135-like) (ZNF140-like).

NFH_MOUSE
θ value	1.06291 (rank : 70)	NC score	0.023235 (rank : 199)
Query Neighborhood Hits	152	Target Neighborhood Hits	2247	Shared Neighborhood Hits	61
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SCG2_MOUSE
θ value	1.06291 (rank : 71)	NC score	0.031046 (rank : 187)
Query Neighborhood Hits	152	Target Neighborhood Hits	74	Shared Neighborhood Hits	3
SwissProt Accessions	Q03517, Q80Y79, Q9CW80	Gene names	Scg2, Chgc, Scg-2
Domain Architecture
Description	Secretogranin-2 precursor (Secretogranin II) (SgII) (Chromogranin C) [Contains: Secretoneurin (SN)].

CO4A2_HUMAN
θ value	1.38821 (rank : 72)	NC score	0.037131 (rank : 170)
Query Neighborhood Hits	152	Target Neighborhood Hits	454	Shared Neighborhood Hits	33
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

HAX1_MOUSE
θ value	1.38821 (rank : 73)	NC score	0.034422 (rank : 180)
Query Neighborhood Hits	152	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	O35387	Gene names	Hax1, Hs1bp1
Domain Architecture	No domain graphic available
Description	HS1-associating protein X-1 (HAX-1) (HS1-binding protein).

HCN4_MOUSE
θ value	1.38821 (rank : 74)	NC score	0.012841 (rank : 215)
Query Neighborhood Hits	152	Target Neighborhood Hits	284	Shared Neighborhood Hits	11
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

IF_MOUSE
θ value	1.38821 (rank : 75)	NC score	0.038259 (rank : 163)
Query Neighborhood Hits	152	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	P52787	Gene names	Gif
Domain Architecture
Description	Gastric intrinsic factor precursor (Intrinsic factor) (IF) (INF).

JHD2A_HUMAN
θ value	1.38821 (rank : 76)	NC score	0.024703 (rank : 192)
Query Neighborhood Hits	152	Target Neighborhood Hits	118	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y4C1, Q53S72, Q68D47, Q68UT9, Q6N050, Q8IY08	Gene names	JMJD1A, JHDM2A, JMJD1, KIAA0742
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2A (EC 1.14.11.-) (Jumonji domain-containing protein 1A).

OGFR_HUMAN
θ value	1.38821 (rank : 77)	NC score	0.034532 (rank : 179)
Query Neighborhood Hits	152	Target Neighborhood Hits	1582	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

TBX18_MOUSE
θ value	1.38821 (rank : 78)	NC score	0.011075 (rank : 219)
Query Neighborhood Hits	152	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EPZ6	Gene names	Tbx18
Domain Architecture
Description	T-box transcription factor TBX18 (T-box protein 18).

AFF4_MOUSE
θ value	1.81305 (rank : 79)	NC score	0.018723 (rank : 202)
Query Neighborhood Hits	152	Target Neighborhood Hits	581	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

CO2A1_HUMAN
θ value	1.81305 (rank : 80)	NC score	0.042780 (rank : 158)
Query Neighborhood Hits	152	Target Neighborhood Hits	486	Shared Neighborhood Hits	36
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO2A1_MOUSE
θ value	1.81305 (rank : 81)	NC score	0.040953 (rank : 160)
Query Neighborhood Hits	152	Target Neighborhood Hits	483	Shared Neighborhood Hits	35
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

DTX2_MOUSE
θ value	1.81305 (rank : 82)	NC score	0.031323 (rank : 184)
Query Neighborhood Hits	152	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R3P2, Q9CZV3, Q9ER07, Q9ER08	Gene names	Dtx2
Domain Architecture
Description	Protein deltex-2 (Deltex-2) (Deltex2) (mDTX2).

EP400_HUMAN
θ value	1.81305 (rank : 83)	NC score	0.019382 (rank : 201)
Query Neighborhood Hits	152	Target Neighborhood Hits	556	Shared Neighborhood Hits	16
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

IF_HUMAN
θ value	1.81305 (rank : 84)	NC score	0.036985 (rank : 172)
Query Neighborhood Hits	152	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	P27352	Gene names	GIF, IFMH
Domain Architecture
Description	Gastric intrinsic factor precursor (Intrinsic factor) (IF) (INF).

JHD2C_HUMAN
θ value	1.81305 (rank : 85)	NC score	0.024551 (rank : 193)
Query Neighborhood Hits	152	Target Neighborhood Hits	279	Shared Neighborhood Hits	11
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

TRIP6_HUMAN
θ value	1.81305 (rank : 86)	NC score	0.010846 (rank : 221)
Query Neighborhood Hits	152	Target Neighborhood Hits	228	Shared Neighborhood Hits	4
SwissProt Accessions	Q15654, O15170, O15275, Q9BTB2, Q9UNT4	Gene names	TRIP6, OIP1
Domain Architecture
Description	Thyroid receptor-interacting protein 6 (TRIP6) (OPA-interacting protein 1) (Zyxin-related protein 1) (ZRP-1).

ZN300_HUMAN
θ value	1.81305 (rank : 87)	NC score	0.001262 (rank : 237)
Query Neighborhood Hits	152	Target Neighborhood Hits	748	Shared Neighborhood Hits	15
SwissProt Accessions	Q96RE9	Gene names	ZNF300
Domain Architecture
Description	Zinc finger protein 300.

CO4A1_HUMAN
θ value	2.36792 (rank : 88)	NC score	0.037040 (rank : 171)
Query Neighborhood Hits	152	Target Neighborhood Hits	425	Shared Neighborhood Hits	36
SwissProt Accessions	P02462	Gene names	COL4A1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

CO4A1_MOUSE
θ value	2.36792 (rank : 89)	NC score	0.037591 (rank : 168)
Query Neighborhood Hits	152	Target Neighborhood Hits	450	Shared Neighborhood Hits	38
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

CONA1_MOUSE
θ value	2.36792 (rank : 90)	NC score	0.037858 (rank : 166)
Query Neighborhood Hits	152	Target Neighborhood Hits	254	Shared Neighborhood Hits	30
SwissProt Accessions	Q8K4G2, Q5SUQ0	Gene names	Col23a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

P3C2G_HUMAN
θ value	2.36792 (rank : 91)	NC score	0.010965 (rank : 220)
Query Neighborhood Hits	152	Target Neighborhood Hits	92	Shared Neighborhood Hits	2
SwissProt Accessions	O75747	Gene names	PIK3C2G
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).

RAI1_MOUSE
θ value	2.36792 (rank : 92)	NC score	0.035560 (rank : 175)
Query Neighborhood Hits	152	Target Neighborhood Hits	344	Shared Neighborhood Hits	15
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

AMBN_MOUSE
θ value	3.0926 (rank : 93)	NC score	0.025073 (rank : 191)
Query Neighborhood Hits	152	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	O55189	Gene names	Ambn
Domain Architecture
Description	Ameloblastin precursor.

CCD96_HUMAN
θ value	3.0926 (rank : 94)	NC score	0.057942 (rank : 120)
Query Neighborhood Hits	152	Target Neighborhood Hits	595	Shared Neighborhood Hits	24
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

COHA1_MOUSE
θ value	3.0926 (rank : 95)	NC score	0.038154 (rank : 164)
Query Neighborhood Hits	152	Target Neighborhood Hits	414	Shared Neighborhood Hits	33
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

ZDHC6_MOUSE
θ value	3.0926 (rank : 96)	NC score	0.016833 (rank : 205)
Query Neighborhood Hits	152	Target Neighborhood Hits	48	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CPV7, Q3U3I8, Q3UT70, Q544H1	Gene names	Zdhhc6
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC6 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 6) (DHHC-6) (H4 homolog).

ZN445_MOUSE
θ value	3.0926 (rank : 97)	NC score	0.001122 (rank : 238)
Query Neighborhood Hits	152	Target Neighborhood Hits	760	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R2V3, Q8K216	Gene names	Znf445, Zfp445
Domain Architecture
Description	Zinc finger protein 445.

AP1B1_HUMAN
θ value	4.03905 (rank : 98)	NC score	0.020067 (rank : 200)
Query Neighborhood Hits	152	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	Q10567, P78436	Gene names	AP1B1, ADTB1, BAM22
Domain Architecture
Description	AP-1 complex subunit beta-1 (Adapter-related protein complex 1 beta-1 subunit) (Beta-adaptin 1) (Adaptor protein complex AP-1 beta-1 subunit) (Golgi adaptor HA1/AP1 adaptin beta subunit) (Clathrin assembly protein complex 1 beta large chain).

CO1A1_MOUSE
θ value	4.03905 (rank : 99)	NC score	0.041337 (rank : 159)
Query Neighborhood Hits	152	Target Neighborhood Hits	457	Shared Neighborhood Hits	37
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

COBA1_HUMAN
θ value	4.03905 (rank : 100)	NC score	0.037408 (rank : 169)
Query Neighborhood Hits	152	Target Neighborhood Hits	491	Shared Neighborhood Hits	35
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

COBA1_MOUSE
θ value	4.03905 (rank : 101)	NC score	0.037890 (rank : 165)
Query Neighborhood Hits	152	Target Neighborhood Hits	487	Shared Neighborhood Hits	36
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

TCAL5_HUMAN
θ value	4.03905 (rank : 102)	NC score	0.018530 (rank : 203)
Query Neighborhood Hits	152	Target Neighborhood Hits	806	Shared Neighborhood Hits	33
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

ZN181_HUMAN
θ value	4.03905 (rank : 103)	NC score	0.002625 (rank : 233)
Query Neighborhood Hits	152	Target Neighborhood Hits	764	Shared Neighborhood Hits	17
SwissProt Accessions	Q2M3W8, Q49A75	Gene names	ZNF181
Domain Architecture	No domain graphic available
Description	Zinc finger protein 181 (HHZ181).

ADCY9_MOUSE
θ value	5.27518 (rank : 104)	NC score	0.007189 (rank : 228)
Query Neighborhood Hits	152	Target Neighborhood Hits	46	Shared Neighborhood Hits	2
SwissProt Accessions	P51830, Q61279	Gene names	Adcy9
Domain Architecture
Description	Adenylate cyclase type 9 (EC 4.6.1.1) (Adenylate cyclase type IX) (ATP pyrophosphate-lyase 9) (Adenylyl cyclase 9) (Adenylyl cyclase type 10) (ACTP10).

CAC1H_HUMAN
θ value	5.27518 (rank : 105)	NC score	0.009112 (rank : 226)
Query Neighborhood Hits	152	Target Neighborhood Hits	307	Shared Neighborhood Hits	19
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

CASP_HUMAN
θ value	5.27518 (rank : 106)	NC score	0.058732 (rank : 117)
Query Neighborhood Hits	152	Target Neighborhood Hits	1131	Shared Neighborhood Hits	23
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CNTRB_HUMAN
θ value	5.27518 (rank : 107)	NC score	0.038897 (rank : 162)
Query Neighborhood Hits	152	Target Neighborhood Hits	690	Shared Neighborhood Hits	21
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CO1A1_HUMAN
θ value	5.27518 (rank : 108)	NC score	0.039357 (rank : 161)
Query Neighborhood Hits	152	Target Neighborhood Hits	475	Shared Neighborhood Hits	33
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

COBA2_MOUSE
θ value	5.27518 (rank : 109)	NC score	0.035414 (rank : 176)
Query Neighborhood Hits	152	Target Neighborhood Hits	501	Shared Neighborhood Hits	35
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

COEA1_HUMAN
θ value	5.27518 (rank : 110)	NC score	0.024274 (rank : 195)
Query Neighborhood Hits	152	Target Neighborhood Hits	427	Shared Neighborhood Hits	28
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

COKA1_HUMAN
θ value	5.27518 (rank : 111)	NC score	0.024538 (rank : 194)
Query Neighborhood Hits	152	Target Neighborhood Hits	403	Shared Neighborhood Hits	27
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

CUTL1_HUMAN
θ value	5.27518 (rank : 112)	NC score	0.055543 (rank : 128)
Query Neighborhood Hits	152	Target Neighborhood Hits	1574	Shared Neighborhood Hits	27
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

GPR37_HUMAN
θ value	5.27518 (rank : 113)	NC score	0.001371 (rank : 236)
Query Neighborhood Hits	152	Target Neighborhood Hits	584	Shared Neighborhood Hits	7
SwissProt Accessions	O15354, O00348, O14768, Q8TD39	Gene names	GPR37
Domain Architecture
Description	Probable G-protein coupled receptor 37 precursor (Endothelin B receptor-like protein 1) (ETBR-LP-1) (Parkin-associated endothelin receptor-like receptor) (PAELR).

HMMR_MOUSE
θ value	5.27518 (rank : 114)	NC score	0.049782 (rank : 155)
Query Neighborhood Hits	152	Target Neighborhood Hits	1178	Shared Neighborhood Hits	20
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

IWS1_MOUSE
θ value	5.27518 (rank : 115)	NC score	0.014945 (rank : 209)
Query Neighborhood Hits	152	Target Neighborhood Hits	1258	Shared Neighborhood Hits	23
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PALM_MOUSE
θ value	5.27518 (rank : 116)	NC score	0.016488 (rank : 206)
Query Neighborhood Hits	152	Target Neighborhood Hits	228	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z0P4, Q9Z0P3	Gene names	Palm
Domain Architecture
Description	Paralemmin.

TNR6A_HUMAN
θ value	5.27518 (rank : 117)	NC score	0.018235 (rank : 204)
Query Neighborhood Hits	152	Target Neighborhood Hits	343	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

ZN334_HUMAN
θ value	5.27518 (rank : 118)	NC score	0.000542 (rank : 240)
Query Neighborhood Hits	152	Target Neighborhood Hits	778	Shared Neighborhood Hits	14
SwissProt Accessions	Q9HCZ1, Q5T6U2, Q9NVW4	Gene names	ZNF334
Domain Architecture
Description	Zinc finger protein 334.

CENG1_MOUSE
θ value	6.88961 (rank : 119)	NC score	0.014941 (rank : 210)
Query Neighborhood Hits	152	Target Neighborhood Hits	531	Shared Neighborhood Hits	13
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

CM018_HUMAN
θ value	6.88961 (rank : 120)	NC score	0.015591 (rank : 208)
Query Neighborhood Hits	152	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H714, Q5W051, Q6PJ74, Q6PK94, Q86XH7, Q8N5J6	Gene names	C13orf18
Domain Architecture	No domain graphic available
Description	Protein C13orf18.

COBA2_HUMAN
θ value	6.88961 (rank : 121)	NC score	0.036870 (rank : 173)
Query Neighborhood Hits	152	Target Neighborhood Hits	408	Shared Neighborhood Hits	34
SwissProt Accessions	P13942, Q07751, Q13271, Q13272, Q13273, Q99866, Q9UIP9	Gene names	COL11A2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

CONA1_HUMAN
θ value	6.88961 (rank : 122)	NC score	0.034718 (rank : 178)
Query Neighborhood Hits	152	Target Neighborhood Hits	281	Shared Neighborhood Hits	30
SwissProt Accessions	Q86Y22, Q8IVR4, Q9NT93	Gene names	COL23A1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

CROCC_MOUSE
θ value	6.88961 (rank : 123)	NC score	0.044161 (rank : 157)
Query Neighborhood Hits	152	Target Neighborhood Hits	1460	Shared Neighborhood Hits	27
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

EGF_MOUSE
θ value	6.88961 (rank : 124)	NC score	0.000723 (rank : 239)
Query Neighborhood Hits	152	Target Neighborhood Hits	358	Shared Neighborhood Hits	2
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

IP6K3_HUMAN
θ value	6.88961 (rank : 125)	NC score	0.009318 (rank : 224)
Query Neighborhood Hits	152	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q96PC2, Q96MQ9	Gene names	IHPK3, IP6K3
Domain Architecture	No domain graphic available
Description	Inositol hexaphosphate kinase 3 (EC 2.7.4.21) (InsP6 kinase 3) (Inositol hexakisphosphate kinase 3).

PIDD_MOUSE
θ value	6.88961 (rank : 126)	NC score	0.003116 (rank : 232)
Query Neighborhood Hits	152	Target Neighborhood Hits	256	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ERV7	Gene names	Lrdd, Pidd
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and death domain-containing protein.

RGS14_HUMAN
θ value	6.88961 (rank : 127)	NC score	0.006446 (rank : 230)
Query Neighborhood Hits	152	Target Neighborhood Hits	77	Shared Neighborhood Hits	2
SwissProt Accessions	O43566, O43565, Q8TD62	Gene names	RGS14
Domain Architecture
Description	Regulator of G-protein signaling 14 (RGS14).

SPEG_HUMAN
θ value	6.88961 (rank : 128)	NC score	-0.004706 (rank : 244)
Query Neighborhood Hits	152	Target Neighborhood Hits	1762	Shared Neighborhood Hits	20
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ZDHC6_HUMAN
θ value	6.88961 (rank : 129)	NC score	0.014261 (rank : 211)
Query Neighborhood Hits	152	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H6R6, Q53G45, Q96IV7, Q9H605	Gene names	ZDHHC6, ZNF376
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC6 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 6) (DHHC-6) (Zinc finger protein 376) (Transmembrane protein H4).

CASP_MOUSE
θ value	8.99809 (rank : 130)	NC score	0.058017 (rank : 119)
Query Neighborhood Hits	152	Target Neighborhood Hits	1152	Shared Neighborhood Hits	24
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CECR6_MOUSE
θ value	8.99809 (rank : 131)	NC score	0.013578 (rank : 213)
Query Neighborhood Hits	152	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q99MX7	Gene names	Cecr6
Domain Architecture	No domain graphic available
Description	Cat eye syndrome critical region protein 6 homolog.

CO5A2_HUMAN
θ value	8.99809 (rank : 132)	NC score	0.032562 (rank : 181)
Query Neighborhood Hits	152	Target Neighborhood Hits	760	Shared Neighborhood Hits	42
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

CO6A1_MOUSE
θ value	8.99809 (rank : 133)	NC score	0.030168 (rank : 189)
Query Neighborhood Hits	152	Target Neighborhood Hits	241	Shared Neighborhood Hits	27
SwissProt Accessions	Q04857	Gene names	Col6a1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

COAA1_HUMAN
θ value	8.99809 (rank : 134)	NC score	0.031147 (rank : 186)
Query Neighborhood Hits	152	Target Neighborhood Hits	316	Shared Neighborhood Hits	35
SwissProt Accessions	Q03692	Gene names	COL10A1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

COEA1_MOUSE
θ value	8.99809 (rank : 135)	NC score	0.023261 (rank : 198)
Query Neighborhood Hits	152	Target Neighborhood Hits	402	Shared Neighborhood Hits	28
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

CTHR1_HUMAN
θ value	8.99809 (rank : 136)	NC score	0.031344 (rank : 183)
Query Neighborhood Hits	152	Target Neighborhood Hits	126	Shared Neighborhood Hits	24
SwissProt Accessions	Q96CG8, Q6UW91, Q8IX63	Gene names	CTHRC1
Domain Architecture	No domain graphic available
Description	Collagen triple helix repeat-containing protein 1 precursor (NMTC1 protein).

CTHR1_MOUSE
θ value	8.99809 (rank : 137)	NC score	0.031291 (rank : 185)
Query Neighborhood Hits	152	Target Neighborhood Hits	123	Shared Neighborhood Hits	24
SwissProt Accessions	Q9D1D6	Gene names	Cthrc1
Domain Architecture	No domain graphic available
Description	Collagen triple helix repeat-containing protein 1 precursor.

CUTL1_MOUSE
θ value	8.99809 (rank : 138)	NC score	0.055623 (rank : 127)
Query Neighborhood Hits	152	Target Neighborhood Hits	1620	Shared Neighborhood Hits	32
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

GRIN2_HUMAN
θ value	8.99809 (rank : 139)	NC score	0.015936 (rank : 207)
Query Neighborhood Hits	152	Target Neighborhood Hits	53	Shared Neighborhood Hits	6
SwissProt Accessions	O60269, Q5SVF0	Gene names	GPRIN2, KIAA0514
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 2 (GRIN2).

HIC1_MOUSE
θ value	8.99809 (rank : 140)	NC score	-0.000288 (rank : 242)
Query Neighborhood Hits	152	Target Neighborhood Hits	863	Shared Neighborhood Hits	17
SwissProt Accessions	Q9R1Y5, Q9R1Y6, Q9R2B0	Gene names	Hic1
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1).

IBP5_HUMAN
θ value	8.99809 (rank : 141)	NC score	0.009090 (rank : 227)
Query Neighborhood Hits	152	Target Neighborhood Hits	68	Shared Neighborhood Hits	3
SwissProt Accessions	P24593	Gene names	IGFBP5, IBP5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

IBP5_MOUSE
θ value	8.99809 (rank : 142)	NC score	0.009122 (rank : 225)
Query Neighborhood Hits	152	Target Neighborhood Hits	68	Shared Neighborhood Hits	3
SwissProt Accessions	Q07079	Gene names	Igfbp5, Igfbp-5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

KS6C1_MOUSE
θ value	8.99809 (rank : 143)	NC score	-0.001954 (rank : 243)
Query Neighborhood Hits	152	Target Neighborhood Hits	700	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BLK9, Q3UDY3, Q6PDY4, Q8BMQ5, Q8BX49	Gene names	Rps6kc1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase).

SRTD1_HUMAN
θ value	8.99809 (rank : 144)	NC score	0.013879 (rank : 212)
Query Neighborhood Hits	152	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UHV2, Q9BUE7	Gene names	SERTAD1, SEI1
Domain Architecture
Description	SERTA domain-containing protein 1 (Transcriptional regulator interacting with the PHD-bromodomain 1) (TRIP-Br1) (CDK4-binding protein p34SEI1) (SEI-1).

ST65G_HUMAN
θ value	8.99809 (rank : 145)	NC score	0.011995 (rank : 218)
Query Neighborhood Hits	152	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	O94864, Q6IB21, Q9H2T6	Gene names	SUPT7L, KIAA0764
Domain Architecture
Description	STAGA complex 65 subunit gamma (STAF65gamma) (SPTF-associated factor 65 gamma) (Suppressor of Ty 7-like) (Adenocarcinoma antigen ART1).

TTLL5_HUMAN
θ value	8.99809 (rank : 146)	NC score	0.006466 (rank : 229)
Query Neighborhood Hits	152	Target Neighborhood Hits	141	Shared Neighborhood Hits	3
SwissProt Accessions	Q6EMB2, Q9P1V5, Q9UPZ4	Gene names	TTLL5, KIAA0998, STAMP
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5 (SRC1 and TIF2-associated modulatory protein).

ZDH24_HUMAN
θ value	8.99809 (rank : 147)	NC score	0.010196 (rank : 223)
Query Neighborhood Hits	152	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	Q6UX98, Q6PEW7, Q9BSJ0	Gene names	ZDHHC24
Domain Architecture	No domain graphic available
Description	Probable palmitoyltransferase ZDHHC24 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 24) (DHHC-24).

ZMYM3_HUMAN
θ value	8.99809 (rank : 148)	NC score	0.023788 (rank : 197)
Query Neighborhood Hits	152	Target Neighborhood Hits	223	Shared Neighborhood Hits	12
SwissProt Accessions	Q14202, O15089	Gene names	ZMYM3, DXS6673E, KIAA0385, ZNF261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261).

ZMYM3_MOUSE
θ value	8.99809 (rank : 149)	NC score	0.023891 (rank : 196)
Query Neighborhood Hits	152	Target Neighborhood Hits	177	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JLM4, Q80U17	Gene names	Zmym3, Kiaa0385, Zfp261, Znf261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261) (DXHXS6673E protein).

ZN553_HUMAN
θ value	8.99809 (rank : 150)	NC score	-0.000058 (rank : 241)
Query Neighborhood Hits	152	Target Neighborhood Hits	760	Shared Neighborhood Hits	12
SwissProt Accessions	Q96MX3, Q4G0R3, Q69YP3, Q96IL9	Gene names	ZNF553
Domain Architecture	No domain graphic available
Description	Zinc finger protein 553.

ZN645_HUMAN
θ value	8.99809 (rank : 151)	NC score	0.012010 (rank : 217)
Query Neighborhood Hits	152	Target Neighborhood Hits	265	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

ZN709_HUMAN
θ value	8.99809 (rank : 152)	NC score	0.001510 (rank : 235)
Query Neighborhood Hits	152	Target Neighborhood Hits	746	Shared Neighborhood Hits	17
SwissProt Accessions	Q8N972	Gene names	ZNF709
Domain Architecture	No domain graphic available
Description	Zinc finger protein 709.

ABR_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.090064 (rank : 86)
Query Neighborhood Hits	152	Target Neighborhood Hits	166	Shared Neighborhood Hits	13
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

ALS2_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.052982 (rank : 140)
Query Neighborhood Hits	152	Target Neighborhood Hits	121	Shared Neighborhood Hits	12
SwissProt Accessions	Q96Q42, Q8N1E0, Q96PC4, Q96Q41, Q9H973, Q9HCK9	Gene names	ALS2, KIAA1563
Domain Architecture
Description	Alsin (Amyotrophic lateral sclerosis protein 2).

ALS2_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.063412 (rank : 107)
Query Neighborhood Hits	152	Target Neighborhood Hits	111	Shared Neighborhood Hits	13
SwissProt Accessions	Q920R0, Q8JZR1, Q9CXJ3	Gene names	Als2
Domain Architecture
Description	Alsin (Amyotrophic lateral sclerosis protein 2 homolog).

ANR26_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.051645 (rank : 145)
Query Neighborhood Hits	152	Target Neighborhood Hits	1614	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ARHG1_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.093487 (rank : 84)
Query Neighborhood Hits	152	Target Neighborhood Hits	176	Shared Neighborhood Hits	32
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

ARHG1_MOUSE
θ value	θ > 10 (rank : 158)	NC score	0.095477 (rank : 79)
Query Neighborhood Hits	152	Target Neighborhood Hits	266	Shared Neighborhood Hits	40
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

ARHG2_HUMAN
θ value	θ > 10 (rank : 159)	NC score	0.074434 (rank : 93)
Query Neighborhood Hits	152	Target Neighborhood Hits	142	Shared Neighborhood Hits	11
SwissProt Accessions	Q92974, O75142, Q15079	Gene names	ARHGEF2, KIAA0651, LFP40
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (GEF-H1 protein) (Proliferating cell nucleolar antigen p40).

ARHG2_MOUSE
θ value	θ > 10 (rank : 160)	NC score	0.100937 (rank : 73)
Query Neighborhood Hits	152	Target Neighborhood Hits	120	Shared Neighborhood Hits	12
SwissProt Accessions	Q60875, O09115	Gene names	Arhgef2, Lbcl1, Lfc
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (Lymphoid blast crisis- like 1) (LBC'S first cousin) (Oncogene LFC) (RHOBIN).

ARHG3_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.061390 (rank : 110)
Query Neighborhood Hits	152	Target Neighborhood Hits	82	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

ARHG3_MOUSE
θ value	θ > 10 (rank : 162)	NC score	0.062688 (rank : 108)
Query Neighborhood Hits	152	Target Neighborhood Hits	85	Shared Neighborhood Hits	8
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

ARHG4_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.094668 (rank : 80)
Query Neighborhood Hits	152	Target Neighborhood Hits	242	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG4_MOUSE
θ value	θ > 10 (rank : 164)	NC score	0.093754 (rank : 82)
Query Neighborhood Hits	152	Target Neighborhood Hits	185	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG5_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.125000 (rank : 63)
Query Neighborhood Hits	152	Target Neighborhood Hits	172	Shared Neighborhood Hits	12
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

ARHG7_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.072783 (rank : 95)
Query Neighborhood Hits	152	Target Neighborhood Hits	347	Shared Neighborhood Hits	16
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

ARHG7_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.060636 (rank : 112)
Query Neighborhood Hits	152	Target Neighborhood Hits	396	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

ARHG8_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.059703 (rank : 115)
Query Neighborhood Hits	152	Target Neighborhood Hits	85	Shared Neighborhood Hits	12
SwissProt Accessions	Q7Z628, Q12773, Q96D82, Q99903, Q9UEN6	Gene names	NET1, ARHGEF8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (p65 Net1 proto- oncogene) (Rho guanine nucleotide exchange factor 8).

ARHG9_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.087314 (rank : 87)
Query Neighborhood Hits	152	Target Neighborhood Hits	235	Shared Neighborhood Hits	11
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

ARHG9_MOUSE
θ value	θ > 10 (rank : 170)	NC score	0.086031 (rank : 88)
Query Neighborhood Hits	152	Target Neighborhood Hits	234	Shared Neighborhood Hits	11
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

ARHGA_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.115382 (rank : 69)
Query Neighborhood Hits	152	Target Neighborhood Hits	187	Shared Neighborhood Hits	12
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ARHGA_MOUSE
θ value	θ > 10 (rank : 172)	NC score	0.117209 (rank : 65)
Query Neighborhood Hits	152	Target Neighborhood Hits	125	Shared Neighborhood Hits	13
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ARHGB_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.071156 (rank : 99)
Query Neighborhood Hits	152	Target Neighborhood Hits	375	Shared Neighborhood Hits	16
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

ARHGC_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.070404 (rank : 100)
Query Neighborhood Hits	152	Target Neighborhood Hits	351	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGC_MOUSE
θ value	θ > 10 (rank : 175)	NC score	0.069960 (rank : 102)
Query Neighborhood Hits	152	Target Neighborhood Hits	344	Shared Neighborhood Hits	14
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGF_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.117125 (rank : 66)
Query Neighborhood Hits	152	Target Neighborhood Hits	214	Shared Neighborhood Hits	17
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

ARHGG_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.107434 (rank : 72)
Query Neighborhood Hits	152	Target Neighborhood Hits	129	Shared Neighborhood Hits	12
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

ARHGG_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.099169 (rank : 77)
Query Neighborhood Hits	152	Target Neighborhood Hits	152	Shared Neighborhood Hits	12
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

BCR_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.091623 (rank : 85)
Query Neighborhood Hits	152	Target Neighborhood Hits	204	Shared Neighborhood Hits	14
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

CARD9_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.056361 (rank : 123)
Query Neighborhood Hits	152	Target Neighborhood Hits	602	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H257, Q5SXM6, Q9H854	Gene names	CARD9
Domain Architecture
Description	Caspase recruitment domain-containing protein 9 (hCARD9).

CCDC6_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.058739 (rank : 116)
Query Neighborhood Hits	152	Target Neighborhood Hits	723	Shared Neighborhood Hits	22
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

CCHCR_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.050008 (rank : 154)
Query Neighborhood Hits	152	Target Neighborhood Hits	932	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

CE290_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.050689 (rank : 152)
Query Neighborhood Hits	152	Target Neighborhood Hits	1553	Shared Neighborhood Hits	22
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CF182_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.053332 (rank : 139)
Query Neighborhood Hits	152	Target Neighborhood Hits	474	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IYX8	Gene names	C6orf182
Domain Architecture	No domain graphic available
Description	Protein C6orf182.

CF182_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.054868 (rank : 131)
Query Neighborhood Hits	152	Target Neighborhood Hits	551	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VDS7, Q9CZE0, Q9D5A1	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf182 homolog.

CJ064_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.117123 (rank : 67)
Query Neighborhood Hits	152	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZS81, Q8N4A3	Gene names	C10orf64
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf64.

CNTRB_MOUSE
θ value	θ > 10 (rank : 187)	NC score	0.054766 (rank : 132)
Query Neighborhood Hits	152	Target Neighborhood Hits	1029	Shared Neighborhood Hits	30
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

ECT2_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.138244 (rank : 62)
Query Neighborhood Hits	152	Target Neighborhood Hits	98	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

ECT2_MOUSE
θ value	θ > 10 (rank : 189)	NC score	0.141903 (rank : 61)
Query Neighborhood Hits	152	Target Neighborhood Hits	98	Shared Neighborhood Hits	13
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

FAN_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.052364 (rank : 142)
Query Neighborhood Hits	152	Target Neighborhood Hits	295	Shared Neighborhood Hits	5
SwissProt Accessions	Q92636	Gene names	NSMAF, FAN
Domain Architecture
Description	Protein FAN (Factor associated with N-SMase activation) (Factor associated with neutral sphingomyelinase activation).

FAN_MOUSE
θ value	θ > 10 (rank : 191)	NC score	0.052263 (rank : 143)
Query Neighborhood Hits	152	Target Neighborhood Hits	292	Shared Neighborhood Hits	6
SwissProt Accessions	O35242	Gene names	Nsmaf, Fan
Domain Architecture
Description	Protein FAN (Factor associated with N-SMase activation) (Factor associated with neutral sphingomyelinase activation).

FARP1_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.150031 (rank : 60)
Query Neighborhood Hits	152	Target Neighborhood Hits	241	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

FARP2_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.155379 (rank : 57)
Query Neighborhood Hits	152	Target Neighborhood Hits	240	Shared Neighborhood Hits	22
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FARP2_MOUSE
θ value	θ > 10 (rank : 194)	NC score	0.153911 (rank : 58)
Query Neighborhood Hits	152	Target Neighborhood Hits	209	Shared Neighborhood Hits	19
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

GNRP_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.094275 (rank : 81)
Query Neighborhood Hits	152	Target Neighborhood Hits	239	Shared Neighborhood Hits	19
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

GNRP_MOUSE
θ value	θ > 10 (rank : 196)	NC score	0.093743 (rank : 83)
Query Neighborhood Hits	152	Target Neighborhood Hits	191	Shared Neighborhood Hits	14
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

GOGA1_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.050903 (rank : 150)
Query Neighborhood Hits	152	Target Neighborhood Hits	1222	Shared Neighborhood Hits	23
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

GOGA2_HUMAN
θ value	θ > 10 (rank : 198)	NC score	0.052892 (rank : 141)
Query Neighborhood Hits	152	Target Neighborhood Hits	856	Shared Neighborhood Hits	21
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

GOGA3_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.050569 (rank : 153)
Query Neighborhood Hits	152	Target Neighborhood Hits	1317	Shared Neighborhood Hits	26
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

GOGA3_MOUSE
θ value	θ > 10 (rank : 200)	NC score	0.054765 (rank : 133)
Query Neighborhood Hits	152	Target Neighborhood Hits	1437	Shared Neighborhood Hits	25
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

GOGA5_MOUSE
θ value	θ > 10 (rank : 201)	NC score	0.051167 (rank : 147)
Query Neighborhood Hits	152	Target Neighborhood Hits	1434	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

HAPIP_HUMAN
θ value	θ > 10 (rank : 202)	NC score	0.116397 (rank : 68)
Query Neighborhood Hits	152	Target Neighborhood Hits	350	Shared Neighborhood Hits	24
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

ITSN1_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.079460 (rank : 89)
Query Neighborhood Hits	152	Target Neighborhood Hits	1757	Shared Neighborhood Hits	33
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN1_MOUSE
θ value	θ > 10 (rank : 204)	NC score	0.079295 (rank : 90)
Query Neighborhood Hits	152	Target Neighborhood Hits	1669	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

ITSN2_HUMAN
θ value	θ > 10 (rank : 205)	NC score	0.078575 (rank : 91)
Query Neighborhood Hits	152	Target Neighborhood Hits	1173	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

ITSN2_MOUSE
θ value	θ > 10 (rank : 206)	NC score	0.077509 (rank : 92)
Query Neighborhood Hits	152	Target Neighborhood Hits	1371	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

KMHN1_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.050992 (rank : 149)
Query Neighborhood Hits	152	Target Neighborhood Hits	950	Shared Neighborhood Hits	19
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

KMHN1_MOUSE
θ value	θ > 10 (rank : 208)	NC score	0.051135 (rank : 148)
Query Neighborhood Hits	152	Target Neighborhood Hits	949	Shared Neighborhood Hits	20
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

LBC_HUMAN
θ value	θ > 10 (rank : 209)	NC score	0.095498 (rank : 78)
Query Neighborhood Hits	152	Target Neighborhood Hits	90	Shared Neighborhood Hits	11
SwissProt Accessions	Q12802	Gene names	LBC
Domain Architecture
Description	LBC oncogene (P47) (Lymphoid blast crisis oncogene).

LRBA_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.056447 (rank : 122)
Query Neighborhood Hits	152	Target Neighborhood Hits	196	Shared Neighborhood Hits	2
SwissProt Accessions	P50851, Q9H2U3, Q9H2U4	Gene names	LRBA, BGL, CDC4L, LBA
Domain Architecture
Description	Lipopolysaccharide-responsive and beige-like anchor protein (CDC4-like protein) (Beige-like protein).

LYST_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.060378 (rank : 113)
Query Neighborhood Hits	152	Target Neighborhood Hits	324	Shared Neighborhood Hits	5
SwissProt Accessions	Q99698, O43274, Q5T2U9, Q96TD7, Q96TD8, Q99709, Q9H133	Gene names	LYST, CHS, CHS1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige homolog).

LYST_MOUSE
θ value	θ > 10 (rank : 212)	NC score	0.064106 (rank : 106)
Query Neighborhood Hits	152	Target Neighborhood Hits	286	Shared Neighborhood Hits	7
SwissProt Accessions	P97412, Q62403, Q8VBS6	Gene names	Lyst, Bg, Chs1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige protein) (CHS1 homolog).

MCF2L_MOUSE
θ value	θ > 10 (rank : 213)	NC score	0.100487 (rank : 74)
Query Neighborhood Hits	152	Target Neighborhood Hits	255	Shared Neighborhood Hits	17
SwissProt Accessions	Q64096	Gene names	Mcf2l, Dbs
Domain Architecture
Description	Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2- transforming sequence-like protein).

MCF2_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.099501 (rank : 76)
Query Neighborhood Hits	152	Target Neighborhood Hits	166	Shared Neighborhood Hits	15
SwissProt Accessions	P10911, P14919, Q5JYJ4, Q8IUF3, Q8IUF4, Q9UJB3	Gene names	MCF2, DBL
Domain Architecture
Description	Proto-oncogene DBL (Proto-oncogene MCF-2) [Contains: MCF2-transforming protein; DBL-transforming protein].

MTMR3_MOUSE
θ value	θ > 10 (rank : 215)	NC score	0.053712 (rank : 136)
Query Neighborhood Hits	152	Target Neighborhood Hits	78	Shared Neighborhood Hits	1
SwissProt Accessions	Q8K296	Gene names	Mtmr3
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48).

NBEAL_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.069993 (rank : 101)
Query Neighborhood Hits	152	Target Neighborhood Hits	200	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZS30, Q6Y876, Q6ZQY5, Q96Q30	Gene names	NBEAL1, ALS2CR17
Domain Architecture	No domain graphic available
Description	Neurobeachin-like 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein).

NBEA_HUMAN
θ value	θ > 10 (rank : 217)	NC score	0.055434 (rank : 130)
Query Neighborhood Hits	152	Target Neighborhood Hits	186	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NFP9, Q9HCM8, Q9NSU1, Q9NW98, Q9Y6J1	Gene names	NBEA, BCL8B, KIAA1544, LYST2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2) (Protein BCL8B).

NBEA_MOUSE
θ value	θ > 10 (rank : 218)	NC score	0.055941 (rank : 125)
Query Neighborhood Hits	152	Target Neighborhood Hits	225	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EPN1, Q8C931, Q9EPM9, Q9EPN0, Q9WVM9	Gene names	Nbea, Lyst2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2).

NGEF_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.112558 (rank : 70)
Query Neighborhood Hits	152	Target Neighborhood Hits	166	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

NGEF_MOUSE
θ value	θ > 10 (rank : 220)	NC score	0.110565 (rank : 71)
Query Neighborhood Hits	152	Target Neighborhood Hits	228	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

PIBF1_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.050840 (rank : 151)
Query Neighborhood Hits	152	Target Neighborhood Hits	1041	Shared Neighborhood Hits	22
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

PKHA5_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.052232 (rank : 144)
Query Neighborhood Hits	152	Target Neighborhood Hits	455	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

PKHA6_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.071277 (rank : 97)
Query Neighborhood Hits	152	Target Neighborhood Hits	556	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA6_MOUSE
θ value	θ > 10 (rank : 224)	NC score	0.066498 (rank : 104)
Query Neighborhood Hits	152	Target Neighborhood Hits	591	Shared Neighborhood Hits	41
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHG1_HUMAN
θ value	θ > 10 (rank : 225)	NC score	0.117831 (rank : 64)
Query Neighborhood Hits	152	Target Neighborhood Hits	174	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

PKHG4_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.100367 (rank : 75)
Query Neighborhood Hits	152	Target Neighborhood Hits	200	Shared Neighborhood Hits	26
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

PREX1_HUMAN
θ value	θ > 10 (rank : 227)	NC score	0.153480 (rank : 59)
Query Neighborhood Hits	152	Target Neighborhood Hits	177	Shared Neighborhood Hits	21
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

RABE2_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.053679 (rank : 137)
Query Neighborhood Hits	152	Target Neighborhood Hits	545	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H5N1	Gene names	RABEP2, RABPT5B
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

RABE2_MOUSE
θ value	θ > 10 (rank : 229)	NC score	0.055457 (rank : 129)
Query Neighborhood Hits	152	Target Neighborhood Hits	598	Shared Neighborhood Hits	20
SwissProt Accessions	Q91WG2, Q99KN3	Gene names	Rabep2, Rabpt5b
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

RGNEF_MOUSE
θ value	θ > 10 (rank : 230)	NC score	0.054653 (rank : 134)
Query Neighborhood Hits	152	Target Neighborhood Hits	641	Shared Neighborhood Hits	24
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

RUFY3_HUMAN
θ value	θ > 10 (rank : 231)	NC score	0.162014 (rank : 56)
Query Neighborhood Hits	152	Target Neighborhood Hits	594	Shared Neighborhood Hits	16
SwissProt Accessions	Q7L099, O94948, Q9UI00	Gene names	RUFY3, KIAA0871
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

RUFY3_MOUSE
θ value	θ > 10 (rank : 232)	NC score	0.163603 (rank : 55)
Query Neighborhood Hits	152	Target Neighborhood Hits	579	Shared Neighborhood Hits	17
SwissProt Accessions	Q9D394, Q3U348, Q3UF96, Q6PE64, Q8VD10	Gene names	Rufy3, D5Bwg0860e, Ripx
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

SOS2_HUMAN
θ value	θ > 10 (rank : 233)	NC score	0.054195 (rank : 135)
Query Neighborhood Hits	152	Target Neighborhood Hits	193	Shared Neighborhood Hits	10
SwissProt Accessions	Q07890, Q15503	Gene names	SOS2
Domain Architecture
Description	Son of sevenless homolog 2 (SOS-2).

SWP70_HUMAN
θ value	θ > 10 (rank : 234)	NC score	0.067896 (rank : 103)
Query Neighborhood Hits	152	Target Neighborhood Hits	973	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SWP70_MOUSE
θ value	θ > 10 (rank : 235)	NC score	0.064423 (rank : 105)
Query Neighborhood Hits	152	Target Neighborhood Hits	1097	Shared Neighborhood Hits	35
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

TIAM1_HUMAN
θ value	θ > 10 (rank : 236)	NC score	0.072972 (rank : 94)
Query Neighborhood Hits	152	Target Neighborhood Hits	225	Shared Neighborhood Hits	12
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TIAM1_MOUSE
θ value	θ > 10 (rank : 237)	NC score	0.071221 (rank : 98)
Query Neighborhood Hits	152	Target Neighborhood Hits	205	Shared Neighborhood Hits	12
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TSC1_HUMAN
θ value	θ > 10 (rank : 238)	NC score	0.056148 (rank : 124)
Query Neighborhood Hits	152	Target Neighborhood Hits	765	Shared Neighborhood Hits	23
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

VAV2_HUMAN
θ value	θ > 10 (rank : 239)	NC score	0.053561 (rank : 138)
Query Neighborhood Hits	152	Target Neighborhood Hits	453	Shared Neighborhood Hits	16
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

VAV2_MOUSE
θ value	θ > 10 (rank : 240)	NC score	0.058354 (rank : 118)
Query Neighborhood Hits	152	Target Neighborhood Hits	456	Shared Neighborhood Hits	21
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

VAV3_HUMAN
θ value	θ > 10 (rank : 241)	NC score	0.056671 (rank : 121)
Query Neighborhood Hits	152	Target Neighborhood Hits	398	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

VAV3_MOUSE
θ value	θ > 10 (rank : 242)	NC score	0.055769 (rank : 126)
Query Neighborhood Hits	152	Target Neighborhood Hits	404	Shared Neighborhood Hits	10
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

VAV_HUMAN
θ value	θ > 10 (rank : 243)	NC score	0.062484 (rank : 109)
Query Neighborhood Hits	152	Target Neighborhood Hits	452	Shared Neighborhood Hits	13
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

VAV_MOUSE
θ value	θ > 10 (rank : 244)	NC score	0.060343 (rank : 114)
Query Neighborhood Hits	152	Target Neighborhood Hits	430	Shared Neighborhood Hits	11
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

Hits sorted by NC score

ZFY28_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	152	Target Neighborhood Hits	152	Shared Neighborhood Hits	152
SwissProt Accessions	Q9HCC9	Gene names	ZFYVE28, KIAA1643
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 28.

ZFY21_MOUSE
NC score	0.813250 (rank : 2)	θ value	3.40345e-15 (rank : 2)
Query Neighborhood Hits	152	Target Neighborhood Hits	72	Shared Neighborhood Hits	57
SwissProt Accessions	Q8VCM3, Q9D1E2	Gene names	Zfyve21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

ZFY21_HUMAN
NC score	0.812010 (rank : 3)	θ value	4.44505e-15 (rank : 3)
Query Neighborhood Hits	152	Target Neighborhood Hits	72	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BQ24, Q86T05, Q96LT1	Gene names	ZFYVE21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

PKHF1_HUMAN
NC score	0.731251 (rank : 4)	θ value	2.28291e-11 (rank : 18)
Query Neighborhood Hits	152	Target Neighborhood Hits	76	Shared Neighborhood Hits	51
SwissProt Accessions	Q96S99, Q96K11, Q9BUB9	Gene names	PLEKHF1, APPD, LAPF, ZFYVE15
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (PH and FYVE domain-containing protein 1) (Phafin-1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains) (Apoptosis-inducing protein) (Zinc finger FYVE domain-containing protein 15).

PKHF2_MOUSE
NC score	0.728674 (rank : 5)	θ value	2.52405e-10 (rank : 27)
Query Neighborhood Hits	152	Target Neighborhood Hits	77	Shared Neighborhood Hits	48
SwissProt Accessions	Q91WB4	Gene names	Plekhf2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2).

PKHF2_HUMAN
NC score	0.727485 (rank : 6)	θ value	2.52405e-10 (rank : 26)
Query Neighborhood Hits	152	Target Neighborhood Hits	75	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H8W4	Gene names	PLEKHF2, ZFYVE18
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2) (PH and FYVE domain-containing protein 2) (Phafin-2) (Zinc finger FYVE domain-containing protein 18).

PKHF1_MOUSE
NC score	0.723896 (rank : 7)	θ value	5.08577e-11 (rank : 22)
Query Neighborhood Hits	152	Target Neighborhood Hits	80	Shared Neighborhood Hits	51
SwissProt Accessions	Q3TB82, Q99M16	Gene names	Plekhf1, Lapf
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains).

ZFYV9_HUMAN
NC score	0.694392 (rank : 8)	θ value	3.89403e-11 (rank : 20)
Query Neighborhood Hits	152	Target Neighborhood Hits	134	Shared Neighborhood Hits	55
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

ZFY16_MOUSE
NC score	0.681424 (rank : 9)	θ value	2.52405e-10 (rank : 29)
Query Neighborhood Hits	152	Target Neighborhood Hits	108	Shared Neighborhood Hits	54
SwissProt Accessions	Q80U44, Q8BRD2, Q8CG97	Gene names	Zfyve16, Kiaa0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosomal- associated FYVE domain protein).

ZFY16_HUMAN
NC score	0.671720 (rank : 10)	θ value	2.52405e-10 (rank : 28)
Query Neighborhood Hits	152	Target Neighborhood Hits	125	Shared Neighborhood Hits	55
SwissProt Accessions	Q7Z3T8, O15023, Q7LAU7, Q86T69, Q8N5L3, Q8NEK3	Gene names	ZFYVE16, KIAA0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome- associated FYVE domain protein).

ZFYV1_HUMAN
NC score	0.650574 (rank : 11)	θ value	1.9326e-10 (rank : 25)
Query Neighborhood Hits	152	Target Neighborhood Hits	166	Shared Neighborhood Hits	54
SwissProt Accessions	Q9HBF4, Q8WYX7, Q96K57, Q9BXP9, Q9HCI3	Gene names	ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (Tandem FYVE fingers-1) (SR3).

ZFYV1_MOUSE
NC score	0.647917 (rank : 12)	θ value	1.47974e-10 (rank : 24)
Query Neighborhood Hits	152	Target Neighborhood Hits	153	Shared Neighborhood Hits	54
SwissProt Accessions	Q810J8	Gene names	Zfyve1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1.

HGS_HUMAN
NC score	0.607053 (rank : 13)	θ value	1.42992e-13 (rank : 8)
Query Neighborhood Hits	152	Target Neighborhood Hits	517	Shared Neighborhood Hits	58
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

HGS_MOUSE
NC score	0.605152 (rank : 14)	θ value	8.38298e-14 (rank : 7)
Query Neighborhood Hits	152	Target Neighborhood Hits	589	Shared Neighborhood Hits	65
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

FYV1_HUMAN
NC score	0.578991 (rank : 15)	θ value	4.16044e-13 (rank : 11)
Query Neighborhood Hits	152	Target Neighborhood Hits	217	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

FYV1_MOUSE
NC score	0.578879 (rank : 16)	θ value	4.16044e-13 (rank : 12)
Query Neighborhood Hits	152	Target Neighborhood Hits	191	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

FGD6_HUMAN
NC score	0.572850 (rank : 17)	θ value	9.26847e-13 (rank : 13)
Query Neighborhood Hits	152	Target Neighborhood Hits	237	Shared Neighborhood Hits	50
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

FGD6_MOUSE
NC score	0.557471 (rank : 18)	θ value	5.08577e-11 (rank : 21)
Query Neighborhood Hits	152	Target Neighborhood Hits	282	Shared Neighborhood Hits	53
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

FGD5_MOUSE
NC score	0.556021 (rank : 19)	θ value	1.87187e-05 (rank : 45)
Query Neighborhood Hits	152	Target Neighborhood Hits	170	Shared Neighborhood Hits	54
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

FGD5_HUMAN
NC score	0.553620 (rank : 20)	θ value	1.17247e-07 (rank : 37)
Query Neighborhood Hits	152	Target Neighborhood Hits	235	Shared Neighborhood Hits	57
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

ZFY19_HUMAN
NC score	0.548233 (rank : 21)	θ value	1.69304e-06 (rank : 42)
Query Neighborhood Hits	152	Target Neighborhood Hits	206	Shared Neighborhood Hits	59
SwissProt Accessions	Q96K21, Q86WC2, Q8WU96	Gene names	ZFYVE19, MPFYVE
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19 (MLL partner containing FYVE domain).

ZFY19_MOUSE
NC score	0.546095 (rank : 22)	θ value	6.43352e-06 (rank : 43)
Query Neighborhood Hits	152	Target Neighborhood Hits	143	Shared Neighborhood Hits	56
SwissProt Accessions	Q9DAZ9, Q8VCV7	Gene names	Zfyve19
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19.

FGD2_HUMAN
NC score	0.533203 (rank : 23)	θ value	2.20605e-14 (rank : 4)
Query Neighborhood Hits	152	Target Neighborhood Hits	151	Shared Neighborhood Hits	50
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

FGD2_MOUSE
NC score	0.530175 (rank : 24)	θ value	3.52202e-12 (rank : 14)
Query Neighborhood Hits	152	Target Neighborhood Hits	163	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

RBNS5_HUMAN
NC score	0.510022 (rank : 25)	θ value	2.44474e-05 (rank : 46)
Query Neighborhood Hits	152	Target Neighborhood Hits	242	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H1K0, Q3KP30, Q59EY8, Q8NAQ1	Gene names	ZFYVE20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20) (110 kDa protein).

RBNS5_MOUSE
NC score	0.504902 (rank : 26)	θ value	2.44474e-05 (rank : 47)
Query Neighborhood Hits	152	Target Neighborhood Hits	266	Shared Neighborhood Hits	50
SwissProt Accessions	Q80Y56, Q8K0L6, Q9CTW0	Gene names	Zfyve20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20).

FGD4_HUMAN
NC score	0.499572 (rank : 27)	θ value	3.89403e-11 (rank : 19)
Query Neighborhood Hits	152	Target Neighborhood Hits	219	Shared Neighborhood Hits	49
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

FGD4_MOUSE
NC score	0.492168 (rank : 28)	θ value	1.80886e-08 (rank : 33)
Query Neighborhood Hits	152	Target Neighborhood Hits	227	Shared Neighborhood Hits	48
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

FGD1_MOUSE
NC score	0.484769 (rank : 29)	θ value	5.26297e-08 (rank : 36)
Query Neighborhood Hits	152	Target Neighborhood Hits	387	Shared Neighborhood Hits	63
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD1_HUMAN
NC score	0.484451 (rank : 30)	θ value	5.26297e-08 (rank : 35)
Query Neighborhood Hits	152	Target Neighborhood Hits	367	Shared Neighborhood Hits	60
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

ZFY27_HUMAN
NC score	0.475461 (rank : 31)	θ value	1.29631e-06 (rank : 41)
Query Neighborhood Hits	152	Target Neighborhood Hits	64	Shared Neighborhood Hits	44
SwissProt Accessions	Q5T4F4, Q5T4F1, Q5T4F2, Q5T4F3, Q8N1K0, Q8N6D6, Q8NCA0, Q8NDE4, Q96M08	Gene names	ZFYVE27
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 27.

ZFY27_MOUSE
NC score	0.471241 (rank : 32)	θ value	6.43352e-06 (rank : 44)
Query Neighborhood Hits	152	Target Neighborhood Hits	53	Shared Neighborhood Hits	44
SwissProt Accessions	Q3TXX3, Q8CFP8	Gene names	Zfyve27
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 27.

FGD3_HUMAN
NC score	0.454668 (rank : 33)	θ value	0.000461057 (rank : 50)
Query Neighborhood Hits	152	Target Neighborhood Hits	249	Shared Neighborhood Hits	66
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

RUFY1_MOUSE
NC score	0.454262 (rank : 34)	θ value	6.41864e-14 (rank : 6)
Query Neighborhood Hits	152	Target Neighborhood Hits	765	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

WDFY1_HUMAN
NC score	0.448592 (rank : 35)	θ value	4.0297e-08 (rank : 34)
Query Neighborhood Hits	152	Target Neighborhood Hits	305	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IWB7, Q9H9D5, Q9P2B3	Gene names	WDFY1, KIAA1435, WDF1, ZFYVE17
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 1 (WD40- and FYVE domain- containing protein 1) (Phosphoinositide-binding protein 1) (FENS-1) (Zinc finger FYVE domain-containing protein 17).

RUFY2_MOUSE
NC score	0.448298 (rank : 36)	θ value	3.18553e-13 (rank : 10)
Query Neighborhood Hits	152	Target Neighborhood Hits	820	Shared Neighborhood Hits	64
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

MTMR3_HUMAN
NC score	0.447706 (rank : 37)	θ value	3.18553e-13 (rank : 9)
Query Neighborhood Hits	152	Target Neighborhood Hits	163	Shared Neighborhood Hits	55
SwissProt Accessions	Q13615, Q9NYN5, Q9NYN6, Q9UDX6, Q9UEG3	Gene names	MTMR3, KIAA0371, ZFYVE10
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Zinc finger FYVE domain-containing protein 10).

RUFY1_HUMAN
NC score	0.446501 (rank : 38)	θ value	6.41864e-14 (rank : 5)
Query Neighborhood Hits	152	Target Neighborhood Hits	848	Shared Neighborhood Hits	65
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

WDFY3_MOUSE
NC score	0.444721 (rank : 39)	θ value	6.00763e-12 (rank : 17)
Query Neighborhood Hits	152	Target Neighborhood Hits	332	Shared Neighborhood Hits	57
SwissProt Accessions	Q6VNB8, Q8C8H7	Gene names	Wdfy3
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Beach domain, WD repeat and FYVE domain-containing protein 1) (BWF1).

WDFY3_HUMAN
NC score	0.442981 (rank : 40)	θ value	6.00763e-12 (rank : 16)
Query Neighborhood Hits	152	Target Neighborhood Hits	348	Shared Neighborhood Hits	55
SwissProt Accessions	Q8IZQ1, Q4W5K5, Q6P0Q5, Q8N1T2, Q96BS7, Q96N85, Q9Y2J7	Gene names	WDFY3, KIAA0993
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy).

WDFY2_MOUSE
NC score	0.438570 (rank : 41)	θ value	1.53129e-07 (rank : 39)
Query Neighborhood Hits	152	Target Neighborhood Hits	337	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BUB4	Gene names	Wdfy2
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2).

WDFY2_HUMAN
NC score	0.435455 (rank : 42)	θ value	1.53129e-07 (rank : 38)
Query Neighborhood Hits	152	Target Neighborhood Hits	332	Shared Neighborhood Hits	51
SwissProt Accessions	Q96P53, Q96CS1	Gene names	WDFY2, WDF2, ZFYVE22
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2) (Zinc finger FYVE domain-containing protein 22).

FGD3_MOUSE
NC score	0.407125 (rank : 43)	θ value	0.0113563 (rank : 52)
Query Neighborhood Hits	152	Target Neighborhood Hits	257	Shared Neighborhood Hits	60
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

RUFY2_HUMAN
NC score	0.355309 (rank : 44)	θ value	3.52202e-12 (rank : 15)
Query Neighborhood Hits	152	Target Neighborhood Hits	1208	Shared Neighborhood Hits	65
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

ANFY1_MOUSE
NC score	0.299942 (rank : 45)	θ value	5.62301e-10 (rank : 32)
Query Neighborhood Hits	152	Target Neighborhood Hits	480	Shared Neighborhood Hits	55
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANFY1_HUMAN
NC score	0.298239 (rank : 46)	θ value	4.30538e-10 (rank : 31)
Query Neighborhood Hits	152	Target Neighborhood Hits	480	Shared Neighborhood Hits	53
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

FYCO1_HUMAN
NC score	0.282143 (rank : 47)	θ value	4.45536e-07 (rank : 40)
Query Neighborhood Hits	152	Target Neighborhood Hits	1149	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

FYCO1_MOUSE
NC score	0.260951 (rank : 48)	θ value	0.000121331 (rank : 48)
Query Neighborhood Hits	152	Target Neighborhood Hits	1059	Shared Neighborhood Hits	63
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

EEA1_MOUSE
NC score	0.257934 (rank : 49)	θ value	3.29651e-10 (rank : 30)
Query Neighborhood Hits	152	Target Neighborhood Hits	1637	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

RNF34_MOUSE
NC score	0.240330 (rank : 50)	θ value	0.00035302 (rank : 49)
Query Neighborhood Hits	152	Target Neighborhood Hits	160	Shared Neighborhood Hits	36
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

EEA1_HUMAN
NC score	0.238708 (rank : 51)	θ value	1.47974e-10 (rank : 23)
Query Neighborhood Hits	152	Target Neighborhood Hits	1796	Shared Neighborhood Hits	68
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

RNF34_HUMAN
NC score	0.230104 (rank : 52)	θ value	0.00175202 (rank : 51)
Query Neighborhood Hits	152	Target Neighborhood Hits	153	Shared Neighborhood Hits	34
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

RFFL_MOUSE
NC score	0.219809 (rank : 53)	θ value	0.0113563 (rank : 53)
Query Neighborhood Hits	152	Target Neighborhood Hits	145	Shared Neighborhood Hits	35
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

RFFL_HUMAN
NC score	0.209064 (rank : 54)	θ value	0.0193708 (rank : 54)
Query Neighborhood Hits	152	Target Neighborhood Hits	175	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

RUFY3_MOUSE
NC score	0.163603 (rank : 55)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	152	Target Neighborhood Hits	579	Shared Neighborhood Hits	17
SwissProt Accessions	Q9D394, Q3U348, Q3UF96, Q6PE64, Q8VD10	Gene names	Rufy3, D5Bwg0860e, Ripx
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

RUFY3_HUMAN
NC score	0.162014 (rank : 56)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	152	Target Neighborhood Hits	594	Shared Neighborhood Hits	16
SwissProt Accessions	Q7L099, O94948, Q9UI00	Gene names	RUFY3, KIAA0871
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

FARP2_HUMAN
NC score	0.155379 (rank : 57)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	152	Target Neighborhood Hits	240	Shared Neighborhood Hits	22
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FARP2_MOUSE
NC score	0.153911 (rank : 58)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	152	Target Neighborhood Hits	209	Shared Neighborhood Hits	19
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

PREX1_HUMAN
NC score	0.153480 (rank : 59)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	152	Target Neighborhood Hits	177	Shared Neighborhood Hits	21
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

FARP1_HUMAN
NC score	0.150031 (rank : 60)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	152	Target Neighborhood Hits	241	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

ECT2_MOUSE
NC score	0.141903 (rank : 61)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	152	Target Neighborhood Hits	98	Shared Neighborhood Hits	13
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

ECT2_HUMAN
NC score	0.138244 (rank : 62)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	152	Target Neighborhood Hits	98	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

ARHG5_HUMAN
NC score	0.125000 (rank : 63)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	152	Target Neighborhood Hits	172	Shared Neighborhood Hits	12
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

PKHG1_HUMAN
NC score	0.117831 (rank : 64)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	152	Target Neighborhood Hits	174	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

ARHGA_MOUSE
NC score	0.117209 (rank : 65)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	152	Target Neighborhood Hits	125	Shared Neighborhood Hits	13
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ARHGF_HUMAN
NC score	0.117125 (rank : 66)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	152	Target Neighborhood Hits	214	Shared Neighborhood Hits	17
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

CJ064_HUMAN
NC score	0.117123 (rank : 67)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	152	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZS81, Q8N4A3	Gene names	C10orf64
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf64.

HAPIP_HUMAN
NC score	0.116397 (rank : 68)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	152	Target Neighborhood Hits	350	Shared Neighborhood Hits	24
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

ARHGA_HUMAN
NC score	0.115382 (rank : 69)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	152	Target Neighborhood Hits	187	Shared Neighborhood Hits	12
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

NGEF_HUMAN
NC score	0.112558 (rank : 70)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	152	Target Neighborhood Hits	166	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

NGEF_MOUSE
NC score	0.110565 (rank : 71)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	152	Target Neighborhood Hits	228	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

ARHGG_HUMAN
NC score	0.107434 (rank : 72)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	152	Target Neighborhood Hits	129	Shared Neighborhood Hits	12
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

ARHG2_MOUSE
NC score	0.100937 (rank : 73)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	152	Target Neighborhood Hits	120	Shared Neighborhood Hits	12
SwissProt Accessions	Q60875, O09115	Gene names	Arhgef2, Lbcl1, Lfc
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (Lymphoid blast crisis- like 1) (LBC'S first cousin) (Oncogene LFC) (RHOBIN).

MCF2L_MOUSE
NC score	0.100487 (rank : 74)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	152	Target Neighborhood Hits	255	Shared Neighborhood Hits	17
SwissProt Accessions	Q64096	Gene names	Mcf2l, Dbs
Domain Architecture
Description	Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2- transforming sequence-like protein).

PKHG4_HUMAN
NC score	0.100367 (rank : 75)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	152	Target Neighborhood Hits	200	Shared Neighborhood Hits	26
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

MCF2_HUMAN
NC score	0.099501 (rank : 76)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	152	Target Neighborhood Hits	166	Shared Neighborhood Hits	15
SwissProt Accessions	P10911, P14919, Q5JYJ4, Q8IUF3, Q8IUF4, Q9UJB3	Gene names	MCF2, DBL
Domain Architecture
Description	Proto-oncogene DBL (Proto-oncogene MCF-2) [Contains: MCF2-transforming protein; DBL-transforming protein].

ARHGG_MOUSE
NC score	0.099169 (rank : 77)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	152	Target Neighborhood Hits	152	Shared Neighborhood Hits	12
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

LBC_HUMAN
NC score	0.095498 (rank : 78)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	152	Target Neighborhood Hits	90	Shared Neighborhood Hits	11
SwissProt Accessions	Q12802	Gene names	LBC
Domain Architecture
Description	LBC oncogene (P47) (Lymphoid blast crisis oncogene).

ARHG1_MOUSE
NC score	0.095477 (rank : 79)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	152	Target Neighborhood Hits	266	Shared Neighborhood Hits	40
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

ARHG4_HUMAN
NC score	0.094668 (rank : 80)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	152	Target Neighborhood Hits	242	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

GNRP_HUMAN
NC score	0.094275 (rank : 81)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	152	Target Neighborhood Hits	239	Shared Neighborhood Hits	19
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

ARHG4_MOUSE
NC score	0.093754 (rank : 82)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	152	Target Neighborhood Hits	185	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

GNRP_MOUSE
NC score	0.093743 (rank : 83)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	152	Target Neighborhood Hits	191	Shared Neighborhood Hits	14
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

ARHG1_HUMAN
NC score	0.093487 (rank : 84)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	152	Target Neighborhood Hits	176	Shared Neighborhood Hits	32
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

BCR_HUMAN
NC score	0.091623 (rank : 85)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	152	Target Neighborhood Hits	204	Shared Neighborhood Hits	14
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

ABR_HUMAN
NC score	0.090064 (rank : 86)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	152	Target Neighborhood Hits	166	Shared Neighborhood Hits	13
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

ARHG9_HUMAN
NC score	0.087314 (rank : 87)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	152	Target Neighborhood Hits	235	Shared Neighborhood Hits	11
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

ARHG9_MOUSE
NC score	0.086031 (rank : 88)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	152	Target Neighborhood Hits	234	Shared Neighborhood Hits	11
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

ITSN1_HUMAN
NC score	0.079460 (rank : 89)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	152	Target Neighborhood Hits	1757	Shared Neighborhood Hits	33
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN1_MOUSE
NC score	0.079295 (rank : 90)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	152	Target Neighborhood Hits	1669	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

ITSN2_HUMAN
NC score	0.078575 (rank : 91)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	152	Target Neighborhood Hits	1173	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

ITSN2_MOUSE
NC score	0.077509 (rank : 92)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	152	Target Neighborhood Hits	1371	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

ARHG2_HUMAN
NC score	0.074434 (rank : 93)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	152	Target Neighborhood Hits	142	Shared Neighborhood Hits	11
SwissProt Accessions	Q92974, O75142, Q15079	Gene names	ARHGEF2, KIAA0651, LFP40
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (GEF-H1 protein) (Proliferating cell nucleolar antigen p40).

TIAM1_HUMAN
NC score	0.072972 (rank : 94)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	152	Target Neighborhood Hits	225	Shared Neighborhood Hits	12
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

ARHG7_HUMAN
NC score	0.072783 (rank : 95)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	152	Target Neighborhood Hits	347	Shared Neighborhood Hits	16
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

TCF20_MOUSE
NC score	0.072419 (rank : 96)	θ value	0.125558 (rank : 57)
Query Neighborhood Hits	152	Target Neighborhood Hits	396	Shared Neighborhood Hits	15
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

PKHA6_HUMAN
NC score	0.071277 (rank : 97)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	152	Target Neighborhood Hits	556	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

TIAM1_MOUSE
NC score	0.071221 (rank : 98)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	152	Target Neighborhood Hits	205	Shared Neighborhood Hits	12
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

ARHGB_HUMAN
NC score	0.071156 (rank : 99)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	152	Target Neighborhood Hits	375	Shared Neighborhood Hits	16
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

ARHGC_HUMAN
NC score	0.070404 (rank : 100)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	152	Target Neighborhood Hits	351	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

NBEAL_HUMAN
NC score	0.069993 (rank : 101)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	152	Target Neighborhood Hits	200	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZS30, Q6Y876, Q6ZQY5, Q96Q30	Gene names	NBEAL1, ALS2CR17
Domain Architecture	No domain graphic available
Description	Neurobeachin-like 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein).

ARHGC_MOUSE
NC score	0.069960 (rank : 102)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	152	Target Neighborhood Hits	344	Shared Neighborhood Hits	14
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

SWP70_HUMAN
NC score	0.067896 (rank : 103)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	152	Target Neighborhood Hits	973	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

PKHA6_MOUSE
NC score	0.066498 (rank : 104)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	152	Target Neighborhood Hits	591	Shared Neighborhood Hits	41
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

SWP70_MOUSE
NC score	0.064423 (rank : 105)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	152	Target Neighborhood Hits	1097	Shared Neighborhood Hits	35
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

LYST_MOUSE
NC score	0.064106 (rank : 106)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	152	Target Neighborhood Hits	286	Shared Neighborhood Hits	7
SwissProt Accessions	P97412, Q62403, Q8VBS6	Gene names	Lyst, Bg, Chs1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige protein) (CHS1 homolog).

ALS2_MOUSE
NC score	0.063412 (rank : 107)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	152	Target Neighborhood Hits	111	Shared Neighborhood Hits	13
SwissProt Accessions	Q920R0, Q8JZR1, Q9CXJ3	Gene names	Als2
Domain Architecture
Description	Alsin (Amyotrophic lateral sclerosis protein 2 homolog).

ARHG3_MOUSE
NC score	0.062688 (rank : 108)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	152	Target Neighborhood Hits	85	Shared Neighborhood Hits	8
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

VAV_HUMAN
NC score	0.062484 (rank : 109)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	152	Target Neighborhood Hits	452	Shared Neighborhood Hits	13
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

ARHG3_HUMAN
NC score	0.061390 (rank : 110)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	152	Target Neighborhood Hits	82	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

TCF20_HUMAN
NC score	0.060780 (rank : 111)	θ value	0.125558 (rank : 56)
Query Neighborhood Hits	152	Target Neighborhood Hits	323	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

ARHG7_MOUSE
NC score	0.060636 (rank : 112)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	152	Target Neighborhood Hits	396	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

LYST_HUMAN
NC score	0.060378 (rank : 113)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	152	Target Neighborhood Hits	324	Shared Neighborhood Hits	5
SwissProt Accessions	Q99698, O43274, Q5T2U9, Q96TD7, Q96TD8, Q99709, Q9H133	Gene names	LYST, CHS, CHS1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige homolog).

VAV_MOUSE
NC score	0.060343 (rank : 114)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	152	Target Neighborhood Hits	430	Shared Neighborhood Hits	11
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

ARHG8_HUMAN
NC score	0.059703 (rank : 115)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	152	Target Neighborhood Hits	85	Shared Neighborhood Hits	12
SwissProt Accessions	Q7Z628, Q12773, Q96D82, Q99903, Q9UEN6	Gene names	NET1, ARHGEF8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (p65 Net1 proto- oncogene) (Rho guanine nucleotide exchange factor 8).

CCDC6_HUMAN
NC score	0.058739 (rank : 116)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	152	Target Neighborhood Hits	723	Shared Neighborhood Hits	22
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

CASP_HUMAN
NC score	0.058732 (rank : 117)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	152	Target Neighborhood Hits	1131	Shared Neighborhood Hits	23
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

VAV2_MOUSE
NC score	0.058354 (rank : 118)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	152	Target Neighborhood Hits	456	Shared Neighborhood Hits	21
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

CASP_MOUSE
NC score	0.058017 (rank : 119)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	152	Target Neighborhood Hits	1152	Shared Neighborhood Hits	24
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CCD96_HUMAN
NC score	0.057942 (rank : 120)	θ value	3.0926 (rank : 94)
Query Neighborhood Hits	152	Target Neighborhood Hits	595	Shared Neighborhood Hits	24
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

VAV3_HUMAN
NC score	0.056671 (rank : 121)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	152	Target Neighborhood Hits	398	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

LRBA_HUMAN
NC score	0.056447 (rank : 122)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	152	Target Neighborhood Hits	196	Shared Neighborhood Hits	2
SwissProt Accessions	P50851, Q9H2U3, Q9H2U4	Gene names	LRBA, BGL, CDC4L, LBA
Domain Architecture
Description	Lipopolysaccharide-responsive and beige-like anchor protein (CDC4-like protein) (Beige-like protein).

CARD9_HUMAN
NC score	0.056361 (rank : 123)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	152	Target Neighborhood Hits	602	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H257, Q5SXM6, Q9H854	Gene names	CARD9
Domain Architecture
Description	Caspase recruitment domain-containing protein 9 (hCARD9).

TSC1_HUMAN
NC score	0.056148 (rank : 124)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	152	Target Neighborhood Hits	765	Shared Neighborhood Hits	23
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

NBEA_MOUSE
NC score	0.055941 (rank : 125)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	152	Target Neighborhood Hits	225	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EPN1, Q8C931, Q9EPM9, Q9EPN0, Q9WVM9	Gene names	Nbea, Lyst2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2).

VAV3_MOUSE
NC score	0.055769 (rank : 126)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	152	Target Neighborhood Hits	404	Shared Neighborhood Hits	10
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

CUTL1_MOUSE
NC score	0.055623 (rank : 127)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	152	Target Neighborhood Hits	1620	Shared Neighborhood Hits	32
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

CUTL1_HUMAN
NC score	0.055543 (rank : 128)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	152	Target Neighborhood Hits	1574	Shared Neighborhood Hits	27
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

RABE2_MOUSE
NC score	0.055457 (rank : 129)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	152	Target Neighborhood Hits	598	Shared Neighborhood Hits	20
SwissProt Accessions	Q91WG2, Q99KN3	Gene names	Rabep2, Rabpt5b
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

NBEA_HUMAN
NC score	0.055434 (rank : 130)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	152	Target Neighborhood Hits	186	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NFP9, Q9HCM8, Q9NSU1, Q9NW98, Q9Y6J1	Gene names	NBEA, BCL8B, KIAA1544, LYST2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2) (Protein BCL8B).

CF182_MOUSE
NC score	0.054868 (rank : 131)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	152	Target Neighborhood Hits	551	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VDS7, Q9CZE0, Q9D5A1	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf182 homolog.

CNTRB_MOUSE
NC score	0.054766 (rank : 132)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	152	Target Neighborhood Hits	1029	Shared Neighborhood Hits	30
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

GOGA3_MOUSE
NC score	0.054765 (rank : 133)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	152	Target Neighborhood Hits	1437	Shared Neighborhood Hits	25
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

RGNEF_MOUSE
NC score	0.054653 (rank : 134)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	152	Target Neighborhood Hits	641	Shared Neighborhood Hits	24
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

SOS2_HUMAN
NC score	0.054195 (rank : 135)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	152	Target Neighborhood Hits	193	Shared Neighborhood Hits	10
SwissProt Accessions	Q07890, Q15503	Gene names	SOS2
Domain Architecture
Description	Son of sevenless homolog 2 (SOS-2).

MTMR3_MOUSE
NC score	0.053712 (rank : 136)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	152	Target Neighborhood Hits	78	Shared Neighborhood Hits	1
SwissProt Accessions	Q8K296	Gene names	Mtmr3
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48).

RABE2_HUMAN
NC score	0.053679 (rank : 137)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	152	Target Neighborhood Hits	545	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H5N1	Gene names	RABEP2, RABPT5B
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

VAV2_HUMAN
NC score	0.053561 (rank : 138)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	152	Target Neighborhood Hits	453	Shared Neighborhood Hits	16
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

CF182_HUMAN
NC score	0.053332 (rank : 139)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	152	Target Neighborhood Hits	474	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IYX8	Gene names	C6orf182
Domain Architecture	No domain graphic available
Description	Protein C6orf182.

ALS2_HUMAN
NC score	0.052982 (rank : 140)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	152	Target Neighborhood Hits	121	Shared Neighborhood Hits	12
SwissProt Accessions	Q96Q42, Q8N1E0, Q96PC4, Q96Q41, Q9H973, Q9HCK9	Gene names	ALS2, KIAA1563
Domain Architecture
Description	Alsin (Amyotrophic lateral sclerosis protein 2).

GOGA2_HUMAN
NC score	0.052892 (rank : 141)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	152	Target Neighborhood Hits	856	Shared Neighborhood Hits	21
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

FAN_HUMAN
NC score	0.052364 (rank : 142)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	152	Target Neighborhood Hits	295	Shared Neighborhood Hits	5
SwissProt Accessions	Q92636	Gene names	NSMAF, FAN
Domain Architecture
Description	Protein FAN (Factor associated with N-SMase activation) (Factor associated with neutral sphingomyelinase activation).

FAN_MOUSE
NC score	0.052263 (rank : 143)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	152	Target Neighborhood Hits	292	Shared Neighborhood Hits	6
SwissProt Accessions	O35242	Gene names	Nsmaf, Fan
Domain Architecture
Description	Protein FAN (Factor associated with N-SMase activation) (Factor associated with neutral sphingomyelinase activation).

PKHA5_HUMAN
NC score	0.052232 (rank : 144)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	152	Target Neighborhood Hits	455	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

ANR26_HUMAN
NC score	0.051645 (rank : 145)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	152	Target Neighborhood Hits	1614	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

BSN_MOUSE
NC score	0.051426 (rank : 146)	θ value	0.813845 (rank : 67)
Query Neighborhood Hits	152	Target Neighborhood Hits	2057	Shared Neighborhood Hits	62
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

GOGA5_MOUSE
NC score	0.051167 (rank : 147)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	152	Target Neighborhood Hits	1434	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

KMHN1_MOUSE
NC score	0.051135 (rank : 148)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	152	Target Neighborhood Hits	949	Shared Neighborhood Hits	20
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

KMHN1_HUMAN
NC score	0.050992 (rank : 149)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	152	Target Neighborhood Hits	950	Shared Neighborhood Hits	19
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

GOGA1_HUMAN
NC score	0.050903 (rank : 150)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	152	Target Neighborhood Hits	1222	Shared Neighborhood Hits	23
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

PIBF1_HUMAN
NC score	0.050840 (rank : 151)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	152	Target Neighborhood Hits	1041	Shared Neighborhood Hits	22
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

CE290_HUMAN
NC score	0.050689 (rank : 152)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	152	Target Neighborhood Hits	1553	Shared Neighborhood Hits	22
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

GOGA3_HUMAN
NC score	0.050569 (rank : 153)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	152	Target Neighborhood Hits	1317	Shared Neighborhood Hits	26
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

CCHCR_MOUSE
NC score	0.050008 (rank : 154)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	152	Target Neighborhood Hits	932	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

HMMR_MOUSE
NC score	0.049782 (rank : 155)	θ value	5.27518 (rank : 114)
Query Neighborhood Hits	152	Target Neighborhood Hits	1178	Shared Neighborhood Hits	20
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

MY18B_HUMAN
NC score	0.045283 (rank : 156)	θ value	0.279714 (rank : 59)
Query Neighborhood Hits	152	Target Neighborhood Hits	1299	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

CROCC_MOUSE
NC score	0.044161 (rank : 157)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	152	Target Neighborhood Hits	1460	Shared Neighborhood Hits	27
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CO2A1_HUMAN
NC score	0.042780 (rank : 158)	θ value	1.81305 (rank : 80)
Query Neighborhood Hits	152	Target Neighborhood Hits	486	Shared Neighborhood Hits	36
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO1A1_MOUSE
NC score	0.041337 (rank : 159)	θ value	4.03905 (rank : 99)
Query Neighborhood Hits	152	Target Neighborhood Hits	457	Shared Neighborhood Hits	37
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO2A1_MOUSE
NC score	0.040953 (rank : 160)	θ value	1.81305 (rank : 81)
Query Neighborhood Hits	152	Target Neighborhood Hits	483	Shared Neighborhood Hits	35
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO1A1_HUMAN
NC score	0.039357 (rank : 161)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	152	Target Neighborhood Hits	475	Shared Neighborhood Hits	33
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CNTRB_HUMAN
NC score	0.038897 (rank : 162)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	152	Target Neighborhood Hits	690	Shared Neighborhood Hits	21
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

IF_MOUSE
NC score	0.038259 (rank : 163)	θ value	1.38821 (rank : 75)
Query Neighborhood Hits	152	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	P52787	Gene names	Gif
Domain Architecture
Description	Gastric intrinsic factor precursor (Intrinsic factor) (IF) (INF).

COHA1_MOUSE
NC score	0.038154 (rank : 164)	θ value	3.0926 (rank : 95)
Query Neighborhood Hits	152	Target Neighborhood Hits	414	Shared Neighborhood Hits	33
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

COBA1_MOUSE
NC score	0.037890 (rank : 165)	θ value	4.03905 (rank : 101)
Query Neighborhood Hits	152	Target Neighborhood Hits	487	Shared Neighborhood Hits	36
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

CONA1_MOUSE
NC score	0.037858 (rank : 166)	θ value	2.36792 (rank : 90)
Query Neighborhood Hits	152	Target Neighborhood Hits	254	Shared Neighborhood Hits	30
SwissProt Accessions	Q8K4G2, Q5SUQ0	Gene names	Col23a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

PER3_HUMAN
NC score	0.037682 (rank : 167)	θ value	0.0252991 (rank : 55)
Query Neighborhood Hits	152	Target Neighborhood Hits	479	Shared Neighborhood Hits	14
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

CO4A1_MOUSE
NC score	0.037591 (rank : 168)	θ value	2.36792 (rank : 89)
Query Neighborhood Hits	152	Target Neighborhood Hits	450	Shared Neighborhood Hits	38
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

COBA1_HUMAN
NC score	0.037408 (rank : 169)	θ value	4.03905 (rank : 100)
Query Neighborhood Hits	152	Target Neighborhood Hits	491	Shared Neighborhood Hits	35
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

CO4A2_HUMAN
NC score	0.037131 (rank : 170)	θ value	1.38821 (rank : 72)
Query Neighborhood Hits	152	Target Neighborhood Hits	454	Shared Neighborhood Hits	33
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

CO4A1_HUMAN
NC score	0.037040 (rank : 171)	θ value	2.36792 (rank : 88)
Query Neighborhood Hits	152	Target Neighborhood Hits	425	Shared Neighborhood Hits	36
SwissProt Accessions	P02462	Gene names	COL4A1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

IF_HUMAN
NC score	0.036985 (rank : 172)	θ value	1.81305 (rank : 84)
Query Neighborhood Hits	152	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	P27352	Gene names	GIF, IFMH
Domain Architecture
Description	Gastric intrinsic factor precursor (Intrinsic factor) (IF) (INF).

COBA2_HUMAN
NC score	0.036870 (rank : 173)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	152	Target Neighborhood Hits	408	Shared Neighborhood Hits	34
SwissProt Accessions	P13942, Q07751, Q13271, Q13272, Q13273, Q99866, Q9UIP9	Gene names	COL11A2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

TAF6L_MOUSE
NC score	0.036232 (rank : 174)	θ value	0.62314 (rank : 66)
Query Neighborhood Hits	152	Target Neighborhood Hits	146	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R2K4, Q8C5T2	Gene names	Taf6l, Paf65a
Domain Architecture
Description	TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (PCAF-associated factor 65 alpha) (PAF65- alpha).

RAI1_MOUSE
NC score	0.035560 (rank : 175)	θ value	2.36792 (rank : 92)
Query Neighborhood Hits	152	Target Neighborhood Hits	344	Shared Neighborhood Hits	15
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

COBA2_MOUSE
NC score	0.035414 (rank : 176)	θ value	5.27518 (rank : 109)
Query Neighborhood Hits	152	Target Neighborhood Hits	501	Shared Neighborhood Hits	35
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

DTX2_HUMAN
NC score	0.035394 (rank : 177)	θ value	0.62314 (rank : 64)
Query Neighborhood Hits	152	Target Neighborhood Hits	84	Shared Neighborhood Hits	4
SwissProt Accessions	Q86UW9, Q96H69, Q9H890, Q9P200	Gene names	DTX2, KIAA1528
Domain Architecture
Description	Protein deltex-2 (Deltex-2) (Deltex2) (hDTX2).

CONA1_HUMAN
NC score	0.034718 (rank : 178)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	152	Target Neighborhood Hits	281	Shared Neighborhood Hits	30
SwissProt Accessions	Q86Y22, Q8IVR4, Q9NT93	Gene names	COL23A1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

OGFR_HUMAN
NC score	0.034532 (rank : 179)	θ value	1.38821 (rank : 77)
Query Neighborhood Hits	152	Target Neighborhood Hits	1582	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

HAX1_MOUSE
NC score	0.034422 (rank : 180)	θ value	1.38821 (rank : 73)
Query Neighborhood Hits	152	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	O35387	Gene names	Hax1, Hs1bp1
Domain Architecture	No domain graphic available
Description	HS1-associating protein X-1 (HAX-1) (HS1-binding protein).

CO5A2_HUMAN
NC score	0.032562 (rank : 181)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	152	Target Neighborhood Hits	760	Shared Neighborhood Hits	42
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

DC1L2_MOUSE
NC score	0.032075 (rank : 182)	θ value	0.62314 (rank : 63)
Query Neighborhood Hits	152	Target Neighborhood Hits	173	Shared Neighborhood Hits	22
SwissProt Accessions	Q6PDL0	Gene names	Dync1li2, Dncli2, Dnclic2
Domain Architecture	No domain graphic available
Description	Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic).

CTHR1_HUMAN
NC score	0.031344 (rank : 183)	θ value	8.99809 (rank : 136)
Query Neighborhood Hits	152	Target Neighborhood Hits	126	Shared Neighborhood Hits	24
SwissProt Accessions	Q96CG8, Q6UW91, Q8IX63	Gene names	CTHRC1
Domain Architecture	No domain graphic available
Description	Collagen triple helix repeat-containing protein 1 precursor (NMTC1 protein).

DTX2_MOUSE
NC score	0.031323 (rank : 184)	θ value	1.81305 (rank : 82)
Query Neighborhood Hits	152	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R3P2, Q9CZV3, Q9ER07, Q9ER08	Gene names	Dtx2
Domain Architecture
Description	Protein deltex-2 (Deltex-2) (Deltex2) (mDTX2).

CTHR1_MOUSE
NC score	0.031291 (rank : 185)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	152	Target Neighborhood Hits	123	Shared Neighborhood Hits	24
SwissProt Accessions	Q9D1D6	Gene names	Cthrc1
Domain Architecture	No domain graphic available
Description	Collagen triple helix repeat-containing protein 1 precursor.

COAA1_HUMAN
NC score	0.031147 (rank : 186)	θ value	8.99809 (rank : 134)
Query Neighborhood Hits	152	Target Neighborhood Hits	316	Shared Neighborhood Hits	35
SwissProt Accessions	Q03692	Gene names	COL10A1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

SCG2_MOUSE
NC score	0.031046 (rank : 187)	θ value	1.06291 (rank : 71)
Query Neighborhood Hits	152	Target Neighborhood Hits	74	Shared Neighborhood Hits	3
SwissProt Accessions	Q03517, Q80Y79, Q9CW80	Gene names	Scg2, Chgc, Scg-2
Domain Architecture
Description	Secretogranin-2 precursor (Secretogranin II) (SgII) (Chromogranin C) [Contains: Secretoneurin (SN)].

WDR22_HUMAN
NC score	0.031031 (rank : 188)	θ value	0.365318 (rank : 60)
Query Neighborhood Hits	152	Target Neighborhood Hits	328	Shared Neighborhood Hits	9
SwissProt Accessions	Q96JK2, O60559, Q8N3V3, Q8N3V5	Gene names	WDR22, BCRG2, KIAA1824
Domain Architecture
Description	WD repeat protein 22 (Breakpoint cluster region protein 2) (BCRP2).

CO6A1_MOUSE
NC score	0.030168 (rank : 189)	θ value	8.99809 (rank : 133)
Query Neighborhood Hits	152	Target Neighborhood Hits	241	Shared Neighborhood Hits	27
SwissProt Accessions	Q04857	Gene names	Col6a1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

AP1B1_MOUSE
NC score	0.027649 (rank : 190)	θ value	0.279714 (rank : 58)
Query Neighborhood Hits	152	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	O35643, Q922E2	Gene names	Ap1b1, Adtb1
Domain Architecture
Description	AP-1 complex subunit beta-1 (Adapter-related protein complex 1 beta-1 subunit) (Beta-adaptin 1) (Adaptor protein complex AP-1 beta-1 subunit) (Golgi adaptor HA1/AP1 adaptin beta subunit) (Clathrin assembly protein complex 1 beta large chain).

AMBN_MOUSE
NC score	0.025073 (rank : 191)	θ value	3.0926 (rank : 93)
Query Neighborhood Hits	152	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	O55189	Gene names	Ambn
Domain Architecture
Description	Ameloblastin precursor.

JHD2A_HUMAN
NC score	0.024703 (rank : 192)	θ value	1.38821 (rank : 76)
Query Neighborhood Hits	152	Target Neighborhood Hits	118	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y4C1, Q53S72, Q68D47, Q68UT9, Q6N050, Q8IY08	Gene names	JMJD1A, JHDM2A, JMJD1, KIAA0742
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2A (EC 1.14.11.-) (Jumonji domain-containing protein 1A).

JHD2C_HUMAN
NC score	0.024551 (rank : 193)	θ value	1.81305 (rank : 85)
Query Neighborhood Hits	152	Target Neighborhood Hits	279	Shared Neighborhood Hits	11
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

COKA1_HUMAN
NC score	0.024538 (rank : 194)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	152	Target Neighborhood Hits	403	Shared Neighborhood Hits	27
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

COEA1_HUMAN
NC score	0.024274 (rank : 195)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	152	Target Neighborhood Hits	427	Shared Neighborhood Hits	28
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

ZMYM3_MOUSE
NC score	0.023891 (rank : 196)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	152	Target Neighborhood Hits	177	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JLM4, Q80U17	Gene names	Zmym3, Kiaa0385, Zfp261, Znf261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261) (DXHXS6673E protein).

ZMYM3_HUMAN
NC score	0.023788 (rank : 197)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	152	Target Neighborhood Hits	223	Shared Neighborhood Hits	12
SwissProt Accessions	Q14202, O15089	Gene names	ZMYM3, DXS6673E, KIAA0385, ZNF261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261).

COEA1_MOUSE
NC score	0.023261 (rank : 198)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	152	Target Neighborhood Hits	402	Shared Neighborhood Hits	28
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

NFH_MOUSE
NC score	0.023235 (rank : 199)	θ value	1.06291 (rank : 70)
Query Neighborhood Hits	152	Target Neighborhood Hits	2247	Shared Neighborhood Hits	61
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

AP1B1_HUMAN
NC score	0.020067 (rank : 200)	θ value	4.03905 (rank : 98)
Query Neighborhood Hits	152	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	Q10567, P78436	Gene names	AP1B1, ADTB1, BAM22
Domain Architecture
Description	AP-1 complex subunit beta-1 (Adapter-related protein complex 1 beta-1 subunit) (Beta-adaptin 1) (Adaptor protein complex AP-1 beta-1 subunit) (Golgi adaptor HA1/AP1 adaptin beta subunit) (Clathrin assembly protein complex 1 beta large chain).

EP400_HUMAN
NC score	0.019382 (rank : 201)	θ value	1.81305 (rank : 83)
Query Neighborhood Hits	152	Target Neighborhood Hits	556	Shared Neighborhood Hits	16
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

AFF4_MOUSE
NC score	0.018723 (rank : 202)	θ value	1.81305 (rank : 79)
Query Neighborhood Hits	152	Target Neighborhood Hits	581	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

TCAL5_HUMAN
NC score	0.018530 (rank : 203)	θ value	4.03905 (rank : 102)
Query Neighborhood Hits	152	Target Neighborhood Hits	806	Shared Neighborhood Hits	33
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

TNR6A_HUMAN
NC score	0.018235 (rank : 204)	θ value	5.27518 (rank : 117)
Query Neighborhood Hits	152	Target Neighborhood Hits	343	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

ZDHC6_MOUSE
NC score	0.016833 (rank : 205)	θ value	3.0926 (rank : 96)
Query Neighborhood Hits	152	Target Neighborhood Hits	48	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CPV7, Q3U3I8, Q3UT70, Q544H1	Gene names	Zdhhc6
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC6 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 6) (DHHC-6) (H4 homolog).

PALM_MOUSE
NC score	0.016488 (rank : 206)	θ value	5.27518 (rank : 116)
Query Neighborhood Hits	152	Target Neighborhood Hits	228	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z0P4, Q9Z0P3	Gene names	Palm
Domain Architecture
Description	Paralemmin.

GRIN2_HUMAN
NC score	0.015936 (rank : 207)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	152	Target Neighborhood Hits	53	Shared Neighborhood Hits	6
SwissProt Accessions	O60269, Q5SVF0	Gene names	GPRIN2, KIAA0514
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 2 (GRIN2).

CM018_HUMAN
NC score	0.015591 (rank : 208)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	152	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H714, Q5W051, Q6PJ74, Q6PK94, Q86XH7, Q8N5J6	Gene names	C13orf18
Domain Architecture	No domain graphic available
Description	Protein C13orf18.

IWS1_MOUSE
NC score	0.014945 (rank : 209)	θ value	5.27518 (rank : 115)
Query Neighborhood Hits	152	Target Neighborhood Hits	1258	Shared Neighborhood Hits	23
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

CENG1_MOUSE
NC score	0.014941 (rank : 210)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	152	Target Neighborhood Hits	531	Shared Neighborhood Hits	13
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

ZDHC6_HUMAN
NC score	0.014261 (rank : 211)	θ value	6.88961 (rank : 129)
Query Neighborhood Hits	152	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H6R6, Q53G45, Q96IV7, Q9H605	Gene names	ZDHHC6, ZNF376
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC6 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 6) (DHHC-6) (Zinc finger protein 376) (Transmembrane protein H4).

SRTD1_HUMAN
NC score	0.013879 (rank : 212)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	152	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UHV2, Q9BUE7	Gene names	SERTAD1, SEI1
Domain Architecture
Description	SERTA domain-containing protein 1 (Transcriptional regulator interacting with the PHD-bromodomain 1) (TRIP-Br1) (CDK4-binding protein p34SEI1) (SEI-1).

CECR6_MOUSE
NC score	0.013578 (rank : 213)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	152	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q99MX7	Gene names	Cecr6
Domain Architecture	No domain graphic available
Description	Cat eye syndrome critical region protein 6 homolog.

SOX12_MOUSE
NC score	0.013125 (rank : 214)	θ value	0.813845 (rank : 68)
Query Neighborhood Hits	152	Target Neighborhood Hits	98	Shared Neighborhood Hits	3
SwissProt Accessions	Q04890, P70417, Q6NXL2	Gene names	Sox12, Sox-12
Domain Architecture	No domain graphic available
Description	SOX-12 protein.

HCN4_MOUSE
NC score	0.012841 (rank : 215)	θ value	1.38821 (rank : 74)
Query Neighborhood Hits	152	Target Neighborhood Hits	284	Shared Neighborhood Hits	11
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

ATS14_HUMAN
NC score	0.012641 (rank : 216)	θ value	0.47712 (rank : 61)
Query Neighborhood Hits	152	Target Neighborhood Hits	382	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

ZN645_HUMAN
NC score	0.012010 (rank : 217)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	152	Target Neighborhood Hits	265	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

ST65G_HUMAN
NC score	0.011995 (rank : 218)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	152	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	O94864, Q6IB21, Q9H2T6	Gene names	SUPT7L, KIAA0764
Domain Architecture
Description	STAGA complex 65 subunit gamma (STAF65gamma) (SPTF-associated factor 65 gamma) (Suppressor of Ty 7-like) (Adenocarcinoma antigen ART1).

TBX18_MOUSE
NC score	0.011075 (rank : 219)	θ value	1.38821 (rank : 78)
Query Neighborhood Hits	152	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EPZ6	Gene names	Tbx18
Domain Architecture
Description	T-box transcription factor TBX18 (T-box protein 18).

P3C2G_HUMAN
NC score	0.010965 (rank : 220)	θ value	2.36792 (rank : 91)
Query Neighborhood Hits	152	Target Neighborhood Hits	92	Shared Neighborhood Hits	2
SwissProt Accessions	O75747	Gene names	PIK3C2G
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).

TRIP6_HUMAN
NC score	0.010846 (rank : 221)	θ value	1.81305 (rank : 86)
Query Neighborhood Hits	152	Target Neighborhood Hits	228	Shared Neighborhood Hits	4
SwissProt Accessions	Q15654, O15170, O15275, Q9BTB2, Q9UNT4	Gene names	TRIP6, OIP1
Domain Architecture
Description	Thyroid receptor-interacting protein 6 (TRIP6) (OPA-interacting protein 1) (Zyxin-related protein 1) (ZRP-1).

GP125_HUMAN
NC score	0.010412 (rank : 222)	θ value	0.62314 (rank : 65)
Query Neighborhood Hits	152	Target Neighborhood Hits	327	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IWK6, Q6UXK9, Q86SQ5, Q8TC55	Gene names	GPR125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

ZDH24_HUMAN
NC score	0.010196 (rank : 223)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	152	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	Q6UX98, Q6PEW7, Q9BSJ0	Gene names	ZDHHC24
Domain Architecture	No domain graphic available
Description	Probable palmitoyltransferase ZDHHC24 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 24) (DHHC-24).

IP6K3_HUMAN
NC score	0.009318 (rank : 224)	θ value	6.88961 (rank : 125)
Query Neighborhood Hits	152	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q96PC2, Q96MQ9	Gene names	IHPK3, IP6K3
Domain Architecture	No domain graphic available
Description	Inositol hexaphosphate kinase 3 (EC 2.7.4.21) (InsP6 kinase 3) (Inositol hexakisphosphate kinase 3).

IBP5_MOUSE
NC score	0.009122 (rank : 225)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	152	Target Neighborhood Hits	68	Shared Neighborhood Hits	3
SwissProt Accessions	Q07079	Gene names	Igfbp5, Igfbp-5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

CAC1H_HUMAN
NC score	0.009112 (rank : 226)	θ value	5.27518 (rank : 105)
Query Neighborhood Hits	152	Target Neighborhood Hits	307	Shared Neighborhood Hits	19
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

IBP5_HUMAN
NC score	0.009090 (rank : 227)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	152	Target Neighborhood Hits	68	Shared Neighborhood Hits	3
SwissProt Accessions	P24593	Gene names	IGFBP5, IBP5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

ADCY9_MOUSE
NC score	0.007189 (rank : 228)	θ value	5.27518 (rank : 104)
Query Neighborhood Hits	152	Target Neighborhood Hits	46	Shared Neighborhood Hits	2
SwissProt Accessions	P51830, Q61279	Gene names	Adcy9
Domain Architecture
Description	Adenylate cyclase type 9 (EC 4.6.1.1) (Adenylate cyclase type IX) (ATP pyrophosphate-lyase 9) (Adenylyl cyclase 9) (Adenylyl cyclase type 10) (ACTP10).

TTLL5_HUMAN
NC score	0.006466 (rank : 229)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	152	Target Neighborhood Hits	141	Shared Neighborhood Hits	3
SwissProt Accessions	Q6EMB2, Q9P1V5, Q9UPZ4	Gene names	TTLL5, KIAA0998, STAMP
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5 (SRC1 and TIF2-associated modulatory protein).

RGS14_HUMAN
NC score	0.006446 (rank : 230)	θ value	6.88961 (rank : 127)
Query Neighborhood Hits	152	Target Neighborhood Hits	77	Shared Neighborhood Hits	2
SwissProt Accessions	O43566, O43565, Q8TD62	Gene names	RGS14
Domain Architecture
Description	Regulator of G-protein signaling 14 (RGS14).

ZNF14_HUMAN
NC score	0.003340 (rank : 231)	θ value	0.47712 (rank : 62)
Query Neighborhood Hits	152	Target Neighborhood Hits	760	Shared Neighborhood Hits	21
SwissProt Accessions	P17017, Q9ULZ5	Gene names	ZNF14, GIOT4, KOX6
Domain Architecture
Description	Zinc finger protein 14 (Zinc finger protein KOX6) (Gonadotropin- inducible transcription repressor 4) (GIOT-4).

PIDD_MOUSE
NC score	0.003116 (rank : 232)	θ value	6.88961 (rank : 126)
Query Neighborhood Hits	152	Target Neighborhood Hits	256	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ERV7	Gene names	Lrdd, Pidd
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and death domain-containing protein.

ZN181_HUMAN
NC score	0.002625 (rank : 233)	θ value	4.03905 (rank : 103)
Query Neighborhood Hits	152	Target Neighborhood Hits	764	Shared Neighborhood Hits	17
SwissProt Accessions	Q2M3W8, Q49A75	Gene names	ZNF181
Domain Architecture	No domain graphic available
Description	Zinc finger protein 181 (HHZ181).

ZN302_HUMAN
NC score	0.002520 (rank : 234)	θ value	0.813845 (rank : 69)
Query Neighborhood Hits	152	Target Neighborhood Hits	755	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NR11, Q9BZD8, Q9P0J4	Gene names	ZNF302, ZNF135L, ZNF140L
Domain Architecture
Description	Zinc finger protein 302 (ZNF135-like) (ZNF140-like).

ZN709_HUMAN
NC score	0.001510 (rank : 235)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	152	Target Neighborhood Hits	746	Shared Neighborhood Hits	17
SwissProt Accessions	Q8N972	Gene names	ZNF709
Domain Architecture	No domain graphic available
Description	Zinc finger protein 709.

GPR37_HUMAN
NC score	0.001371 (rank : 236)	θ value	5.27518 (rank : 113)
Query Neighborhood Hits	152	Target Neighborhood Hits	584	Shared Neighborhood Hits	7
SwissProt Accessions	O15354, O00348, O14768, Q8TD39	Gene names	GPR37
Domain Architecture
Description	Probable G-protein coupled receptor 37 precursor (Endothelin B receptor-like protein 1) (ETBR-LP-1) (Parkin-associated endothelin receptor-like receptor) (PAELR).

ZN300_HUMAN
NC score	0.001262 (rank : 237)	θ value	1.81305 (rank : 87)
Query Neighborhood Hits	152	Target Neighborhood Hits	748	Shared Neighborhood Hits	15
SwissProt Accessions	Q96RE9	Gene names	ZNF300
Domain Architecture
Description	Zinc finger protein 300.

ZN445_MOUSE
NC score	0.001122 (rank : 238)	θ value	3.0926 (rank : 97)
Query Neighborhood Hits	152	Target Neighborhood Hits	760	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R2V3, Q8K216	Gene names	Znf445, Zfp445
Domain Architecture
Description	Zinc finger protein 445.

EGF_MOUSE
NC score	0.000723 (rank : 239)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	152	Target Neighborhood Hits	358	Shared Neighborhood Hits	2
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

ZN334_HUMAN
NC score	0.000542 (rank : 240)	θ value	5.27518 (rank : 118)
Query Neighborhood Hits	152	Target Neighborhood Hits	778	Shared Neighborhood Hits	14
SwissProt Accessions	Q9HCZ1, Q5T6U2, Q9NVW4	Gene names	ZNF334
Domain Architecture
Description	Zinc finger protein 334.

ZN553_HUMAN
NC score	-0.000058 (rank : 241)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	152	Target Neighborhood Hits	760	Shared Neighborhood Hits	12
SwissProt Accessions	Q96MX3, Q4G0R3, Q69YP3, Q96IL9	Gene names	ZNF553
Domain Architecture	No domain graphic available
Description	Zinc finger protein 553.

HIC1_MOUSE
NC score	-0.000288 (rank : 242)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	152	Target Neighborhood Hits	863	Shared Neighborhood Hits	17
SwissProt Accessions	Q9R1Y5, Q9R1Y6, Q9R2B0	Gene names	Hic1
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1).

KS6C1_MOUSE
NC score	-0.001954 (rank : 243)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	152	Target Neighborhood Hits	700	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BLK9, Q3UDY3, Q6PDY4, Q8BMQ5, Q8BX49	Gene names	Rps6kc1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase).

SPEG_HUMAN
NC score	-0.004706 (rank : 244)	θ value	6.88961 (rank : 128)
Query Neighborhood Hits	152	Target Neighborhood Hits	1762	Shared Neighborhood Hits	20
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).