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Network neighborhood for query Sequence : MCF2L_MOUSE

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MCF2L_MOUSE
SwissProt Accessions	Q64096	Gene names	Mcf2l, Dbs
Domain Architecture
Description	Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2- transforming sequence-like protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MCF2L_MOUSE
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	255	Target Neighborhood Hits	255	Shared Neighborhood Hits	255
SwissProt Accessions	Q64096	Gene names	Mcf2l, Dbs
Domain Architecture
Description	Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2- transforming sequence-like protein).

MCF2_HUMAN
θ value	0 (rank : 2)	NC score	0.925254 (rank : 2)
Query Neighborhood Hits	255	Target Neighborhood Hits	166	Shared Neighborhood Hits	101
SwissProt Accessions	P10911, P14919, Q5JYJ4, Q8IUF3, Q8IUF4, Q9UJB3	Gene names	MCF2, DBL
Domain Architecture
Description	Proto-oncogene DBL (Proto-oncogene MCF-2) [Contains: MCF2-transforming protein; DBL-transforming protein].

HAPIP_HUMAN
θ value	3.48141e-52 (rank : 3)	NC score	0.784259 (rank : 3)
Query Neighborhood Hits	255	Target Neighborhood Hits	350	Shared Neighborhood Hits	133
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

TRIO_HUMAN
θ value	6.56568e-51 (rank : 4)	NC score	0.324815 (rank : 68)
Query Neighborhood Hits	255	Target Neighborhood Hits	1580	Shared Neighborhood Hits	173
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

DUET_HUMAN
θ value	7.25919e-50 (rank : 5)	NC score	0.273857 (rank : 75)
Query Neighborhood Hits	255	Target Neighborhood Hits	1220	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

PKHG4_HUMAN
θ value	3.73686e-38 (rank : 6)	NC score	0.762293 (rank : 5)
Query Neighborhood Hits	255	Target Neighborhood Hits	200	Shared Neighborhood Hits	62
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

PKHG1_HUMAN
θ value	1.37539e-32 (rank : 7)	NC score	0.780043 (rank : 4)
Query Neighborhood Hits	255	Target Neighborhood Hits	174	Shared Neighborhood Hits	72
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

OBSCN_HUMAN
θ value	1.12775e-26 (rank : 8)	NC score	0.157982 (rank : 121)
Query Neighborhood Hits	255	Target Neighborhood Hits	1931	Shared Neighborhood Hits	82
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

ARHG4_HUMAN
θ value	1.6852e-22 (rank : 9)	NC score	0.695783 (rank : 7)
Query Neighborhood Hits	255	Target Neighborhood Hits	242	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG4_MOUSE
θ value	4.15078e-21 (rank : 10)	NC score	0.713800 (rank : 6)
Query Neighborhood Hits	255	Target Neighborhood Hits	185	Shared Neighborhood Hits	81
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

PREX1_HUMAN
θ value	7.32683e-18 (rank : 11)	NC score	0.680316 (rank : 10)
Query Neighborhood Hits	255	Target Neighborhood Hits	177	Shared Neighborhood Hits	71
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

ARHG9_HUMAN
θ value	8.95645e-16 (rank : 12)	NC score	0.691921 (rank : 8)
Query Neighborhood Hits	255	Target Neighborhood Hits	235	Shared Neighborhood Hits	91
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

ARHG9_MOUSE
θ value	8.95645e-16 (rank : 13)	NC score	0.691869 (rank : 9)
Query Neighborhood Hits	255	Target Neighborhood Hits	234	Shared Neighborhood Hits	91
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

VAV_HUMAN
θ value	1.99529e-15 (rank : 14)	NC score	0.518553 (rank : 34)
Query Neighborhood Hits	255	Target Neighborhood Hits	452	Shared Neighborhood Hits	103
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

VAV_MOUSE
θ value	4.44505e-15 (rank : 15)	NC score	0.527581 (rank : 30)
Query Neighborhood Hits	255	Target Neighborhood Hits	430	Shared Neighborhood Hits	106
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

TIAM1_HUMAN
θ value	8.38298e-14 (rank : 16)	NC score	0.644180 (rank : 12)
Query Neighborhood Hits	255	Target Neighborhood Hits	225	Shared Neighborhood Hits	77
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

VAV2_MOUSE
θ value	1.09485e-13 (rank : 17)	NC score	0.509097 (rank : 36)
Query Neighborhood Hits	255	Target Neighborhood Hits	456	Shared Neighborhood Hits	106
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

VAV2_HUMAN
θ value	1.86753e-13 (rank : 18)	NC score	0.507227 (rank : 37)
Query Neighborhood Hits	255	Target Neighborhood Hits	453	Shared Neighborhood Hits	105
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

TIAM1_MOUSE
θ value	2.43908e-13 (rank : 19)	NC score	0.650670 (rank : 11)
Query Neighborhood Hits	255	Target Neighborhood Hits	205	Shared Neighborhood Hits	75
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

FGD2_HUMAN
θ value	5.43371e-13 (rank : 20)	NC score	0.571470 (rank : 15)
Query Neighborhood Hits	255	Target Neighborhood Hits	151	Shared Neighborhood Hits	74
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

FGD3_HUMAN
θ value	4.59992e-12 (rank : 21)	NC score	0.578579 (rank : 14)
Query Neighborhood Hits	255	Target Neighborhood Hits	249	Shared Neighborhood Hits	70
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

VAV3_HUMAN
θ value	7.84624e-12 (rank : 22)	NC score	0.500207 (rank : 39)
Query Neighborhood Hits	255	Target Neighborhood Hits	398	Shared Neighborhood Hits	97
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

FGD3_MOUSE
θ value	1.33837e-11 (rank : 23)	NC score	0.603387 (rank : 13)
Query Neighborhood Hits	255	Target Neighborhood Hits	257	Shared Neighborhood Hits	72
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

SPTA2_HUMAN
θ value	2.28291e-11 (rank : 24)	NC score	0.332500 (rank : 66)
Query Neighborhood Hits	255	Target Neighborhood Hits	888	Shared Neighborhood Hits	152
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

FGD2_MOUSE
θ value	2.98157e-11 (rank : 25)	NC score	0.568566 (rank : 16)
Query Neighborhood Hits	255	Target Neighborhood Hits	163	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

ARHG7_HUMAN
θ value	5.08577e-11 (rank : 26)	NC score	0.552176 (rank : 22)
Query Neighborhood Hits	255	Target Neighborhood Hits	347	Shared Neighborhood Hits	104
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

VAV3_MOUSE
θ value	5.08577e-11 (rank : 27)	NC score	0.497226 (rank : 40)
Query Neighborhood Hits	255	Target Neighborhood Hits	404	Shared Neighborhood Hits	98
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

ARHG7_MOUSE
θ value	9.59137e-10 (rank : 28)	NC score	0.550704 (rank : 23)
Query Neighborhood Hits	255	Target Neighborhood Hits	396	Shared Neighborhood Hits	114
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

DNMBP_MOUSE
θ value	1.25267e-09 (rank : 29)	NC score	0.522153 (rank : 32)
Query Neighborhood Hits	255	Target Neighborhood Hits	435	Shared Neighborhood Hits	98
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

FGD1_HUMAN
θ value	8.11959e-09 (rank : 30)	NC score	0.529783 (rank : 27)
Query Neighborhood Hits	255	Target Neighborhood Hits	367	Shared Neighborhood Hits	79
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD1_MOUSE
θ value	1.06045e-08 (rank : 31)	NC score	0.528938 (rank : 28)
Query Neighborhood Hits	255	Target Neighborhood Hits	387	Shared Neighborhood Hits	78
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

ARHG6_HUMAN
θ value	1.80886e-08 (rank : 32)	NC score	0.525845 (rank : 31)
Query Neighborhood Hits	255	Target Neighborhood Hits	376	Shared Neighborhood Hits	107
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

ARHG6_MOUSE
θ value	3.08544e-08 (rank : 33)	NC score	0.506842 (rank : 38)
Query Neighborhood Hits	255	Target Neighborhood Hits	394	Shared Neighborhood Hits	108
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

DNMBP_HUMAN
θ value	5.26297e-08 (rank : 34)	NC score	0.519532 (rank : 33)
Query Neighborhood Hits	255	Target Neighborhood Hits	413	Shared Neighborhood Hits	112
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

FGD4_MOUSE
θ value	5.26297e-08 (rank : 35)	NC score	0.556702 (rank : 21)
Query Neighborhood Hits	255	Target Neighborhood Hits	227	Shared Neighborhood Hits	76
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

FGD6_MOUSE
θ value	5.26297e-08 (rank : 36)	NC score	0.481788 (rank : 42)
Query Neighborhood Hits	255	Target Neighborhood Hits	282	Shared Neighborhood Hits	77
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

ARHGA_HUMAN
θ value	6.87365e-08 (rank : 37)	NC score	0.532218 (rank : 25)
Query Neighborhood Hits	255	Target Neighborhood Hits	187	Shared Neighborhood Hits	78
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

FGD6_HUMAN
θ value	6.87365e-08 (rank : 38)	NC score	0.479864 (rank : 44)
Query Neighborhood Hits	255	Target Neighborhood Hits	237	Shared Neighborhood Hits	72
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

ARHG8_HUMAN
θ value	8.97725e-08 (rank : 39)	NC score	0.563263 (rank : 17)
Query Neighborhood Hits	255	Target Neighborhood Hits	85	Shared Neighborhood Hits	68
SwissProt Accessions	Q7Z628, Q12773, Q96D82, Q99903, Q9UEN6	Gene names	NET1, ARHGEF8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (p65 Net1 proto- oncogene) (Rho guanine nucleotide exchange factor 8).

ARHG8_MOUSE
θ value	1.17247e-07 (rank : 40)	NC score	0.545090 (rank : 24)
Query Neighborhood Hits	255	Target Neighborhood Hits	79	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Z206, Q8C4I0, Q9Z1L7	Gene names	Net1, Arhgef8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (Rho guanine nucleotide exchange factor 8).

ITSN2_MOUSE
θ value	1.99992e-07 (rank : 41)	NC score	0.420114 (rank : 52)
Query Neighborhood Hits	255	Target Neighborhood Hits	1371	Shared Neighborhood Hits	188
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

ARHGA_MOUSE
θ value	2.61198e-07 (rank : 42)	NC score	0.529993 (rank : 26)
Query Neighborhood Hits	255	Target Neighborhood Hits	125	Shared Neighborhood Hits	70
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

FGD4_HUMAN
θ value	2.61198e-07 (rank : 43)	NC score	0.557293 (rank : 20)
Query Neighborhood Hits	255	Target Neighborhood Hits	219	Shared Neighborhood Hits	81
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

SPTA1_MOUSE
θ value	2.61198e-07 (rank : 44)	NC score	0.329631 (rank : 67)
Query Neighborhood Hits	255	Target Neighborhood Hits	675	Shared Neighborhood Hits	140
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

ITSN1_HUMAN
θ value	4.45536e-07 (rank : 45)	NC score	0.404160 (rank : 57)
Query Neighborhood Hits	255	Target Neighborhood Hits	1757	Shared Neighborhood Hits	195
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN2_HUMAN
θ value	4.45536e-07 (rank : 46)	NC score	0.436879 (rank : 49)
Query Neighborhood Hits	255	Target Neighborhood Hits	1173	Shared Neighborhood Hits	184
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

SMC3_HUMAN
θ value	5.81887e-07 (rank : 47)	NC score	0.159352 (rank : 116)
Query Neighborhood Hits	255	Target Neighborhood Hits	1186	Shared Neighborhood Hits	127
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
θ value	5.81887e-07 (rank : 48)	NC score	0.158940 (rank : 118)
Query Neighborhood Hits	255	Target Neighborhood Hits	1187	Shared Neighborhood Hits	128
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

ARHG3_HUMAN
θ value	7.59969e-07 (rank : 49)	NC score	0.562683 (rank : 18)
Query Neighborhood Hits	255	Target Neighborhood Hits	82	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

ARHG3_MOUSE
θ value	7.59969e-07 (rank : 50)	NC score	0.560406 (rank : 19)
Query Neighborhood Hits	255	Target Neighborhood Hits	85	Shared Neighborhood Hits	66
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

ITSN1_MOUSE
θ value	2.21117e-06 (rank : 51)	NC score	0.402862 (rank : 58)
Query Neighborhood Hits	255	Target Neighborhood Hits	1669	Shared Neighborhood Hits	196
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

FARP2_MOUSE
θ value	1.87187e-05 (rank : 52)	NC score	0.376570 (rank : 62)
Query Neighborhood Hits	255	Target Neighborhood Hits	209	Shared Neighborhood Hits	70
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FARP2_HUMAN
θ value	3.19293e-05 (rank : 53)	NC score	0.356290 (rank : 65)
Query Neighborhood Hits	255	Target Neighborhood Hits	240	Shared Neighborhood Hits	68
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

SPTA1_HUMAN
θ value	3.19293e-05 (rank : 54)	NC score	0.315903 (rank : 69)
Query Neighborhood Hits	255	Target Neighborhood Hits	748	Shared Neighborhood Hits	144
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SPTN5_HUMAN
θ value	3.19293e-05 (rank : 55)	NC score	0.249341 (rank : 77)
Query Neighborhood Hits	255	Target Neighborhood Hits	674	Shared Neighborhood Hits	108
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

RGNEF_MOUSE
θ value	5.44631e-05 (rank : 56)	NC score	0.398053 (rank : 61)
Query Neighborhood Hits	255	Target Neighborhood Hits	641	Shared Neighborhood Hits	127
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

NCF1_HUMAN
θ value	7.1131e-05 (rank : 57)	NC score	0.251849 (rank : 76)
Query Neighborhood Hits	255	Target Neighborhood Hits	198	Shared Neighborhood Hits	49
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

NCF1_MOUSE
θ value	0.00035302 (rank : 58)	NC score	0.236270 (rank : 80)
Query Neighborhood Hits	255	Target Neighborhood Hits	198	Shared Neighborhood Hits	48
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

NGEF_MOUSE
θ value	0.00035302 (rank : 59)	NC score	0.467313 (rank : 47)
Query Neighborhood Hits	255	Target Neighborhood Hits	228	Shared Neighborhood Hits	75
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

GCC2_MOUSE
θ value	0.000461057 (rank : 60)	NC score	0.151300 (rank : 135)
Query Neighborhood Hits	255	Target Neighborhood Hits	1619	Shared Neighborhood Hits	132
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

GOGB1_HUMAN
θ value	0.000461057 (rank : 61)	NC score	0.158505 (rank : 119)
Query Neighborhood Hits	255	Target Neighborhood Hits	2297	Shared Neighborhood Hits	152
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

LBC_HUMAN
θ value	0.000461057 (rank : 62)	NC score	0.417837 (rank : 54)
Query Neighborhood Hits	255	Target Neighborhood Hits	90	Shared Neighborhood Hits	63
SwissProt Accessions	Q12802	Gene names	LBC
Domain Architecture
Description	LBC oncogene (P47) (Lymphoid blast crisis oncogene).

NGEF_HUMAN
θ value	0.000461057 (rank : 63)	NC score	0.472077 (rank : 46)
Query Neighborhood Hits	255	Target Neighborhood Hits	166	Shared Neighborhood Hits	75
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

ARHGG_HUMAN
θ value	0.000602161 (rank : 64)	NC score	0.491509 (rank : 41)
Query Neighborhood Hits	255	Target Neighborhood Hits	129	Shared Neighborhood Hits	68
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

ARHGG_MOUSE
θ value	0.000786445 (rank : 65)	NC score	0.480615 (rank : 43)
Query Neighborhood Hits	255	Target Neighborhood Hits	152	Shared Neighborhood Hits	75
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

EEA1_MOUSE
θ value	0.000786445 (rank : 66)	NC score	0.179035 (rank : 106)
Query Neighborhood Hits	255	Target Neighborhood Hits	1637	Shared Neighborhood Hits	145
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

ACTN1_HUMAN
θ value	0.00102713 (rank : 67)	NC score	0.186668 (rank : 96)
Query Neighborhood Hits	255	Target Neighborhood Hits	221	Shared Neighborhood Hits	54
SwissProt Accessions	P12814, Q9BTN1	Gene names	ACTN1
Domain Architecture
Description	Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein).

ACTN1_MOUSE
θ value	0.00102713 (rank : 68)	NC score	0.186156 (rank : 97)
Query Neighborhood Hits	255	Target Neighborhood Hits	216	Shared Neighborhood Hits	51
SwissProt Accessions	Q7TPR4	Gene names	Actn1
Domain Architecture
Description	Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein).

BPAEA_HUMAN
θ value	0.00102713 (rank : 69)	NC score	0.211333 (rank : 90)
Query Neighborhood Hits	255	Target Neighborhood Hits	1369	Shared Neighborhood Hits	129
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

SPTB1_MOUSE
θ value	0.00102713 (rank : 70)	NC score	0.234781 (rank : 81)
Query Neighborhood Hits	255	Target Neighborhood Hits	543	Shared Neighborhood Hits	111
SwissProt Accessions	P15508	Gene names	Sptb, Spnb-1, Spnb1, Sptb1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

ARHGC_HUMAN
θ value	0.00134147 (rank : 71)	NC score	0.420510 (rank : 51)
Query Neighborhood Hits	255	Target Neighborhood Hits	351	Shared Neighborhood Hits	83
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGC_MOUSE
θ value	0.00175202 (rank : 72)	NC score	0.409436 (rank : 56)
Query Neighborhood Hits	255	Target Neighborhood Hits	344	Shared Neighborhood Hits	82
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGF_HUMAN
θ value	0.00175202 (rank : 73)	NC score	0.411457 (rank : 55)
Query Neighborhood Hits	255	Target Neighborhood Hits	214	Shared Neighborhood Hits	64
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

SPTB1_HUMAN
θ value	0.00175202 (rank : 74)	NC score	0.230321 (rank : 82)
Query Neighborhood Hits	255	Target Neighborhood Hits	541	Shared Neighborhood Hits	102
SwissProt Accessions	P11277, Q15510, Q15519	Gene names	SPTB, SPTB1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

NUMA1_HUMAN
θ value	0.00298849 (rank : 75)	NC score	0.155000 (rank : 126)
Query Neighborhood Hits	255	Target Neighborhood Hits	1523	Shared Neighborhood Hits	135
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

SPTN4_HUMAN
θ value	0.00390308 (rank : 76)	NC score	0.222607 (rank : 83)
Query Neighborhood Hits	255	Target Neighborhood Hits	570	Shared Neighborhood Hits	103
SwissProt Accessions	Q9H254, Q9H1K7, Q9H1K8, Q9H1K9, Q9H3G8, Q9HCD0	Gene names	SPTBN4, KIAA1642, SPTBN3
Domain Architecture
Description	Spectrin beta chain, brain 3 (Spectrin, non-erythroid beta chain 3) (Beta-IV spectrin).

ACTN2_MOUSE
θ value	0.00665767 (rank : 77)	NC score	0.183578 (rank : 100)
Query Neighborhood Hits	255	Target Neighborhood Hits	287	Shared Neighborhood Hits	68
SwissProt Accessions	Q9JI91	Gene names	Actn2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

ACTN3_HUMAN
θ value	0.00665767 (rank : 78)	NC score	0.181934 (rank : 105)
Query Neighborhood Hits	255	Target Neighborhood Hits	272	Shared Neighborhood Hits	68
SwissProt Accessions	Q08043	Gene names	ACTN3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

ARHG1_HUMAN
θ value	0.00665767 (rank : 79)	NC score	0.440452 (rank : 48)
Query Neighborhood Hits	255	Target Neighborhood Hits	176	Shared Neighborhood Hits	68
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

ARHGB_HUMAN
θ value	0.00665767 (rank : 80)	NC score	0.427978 (rank : 50)
Query Neighborhood Hits	255	Target Neighborhood Hits	375	Shared Neighborhood Hits	82
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

BPA1_MOUSE
θ value	0.00665767 (rank : 81)	NC score	0.219104 (rank : 85)
Query Neighborhood Hits	255	Target Neighborhood Hits	1477	Shared Neighborhood Hits	142
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BPAEA_MOUSE
θ value	0.00665767 (rank : 82)	NC score	0.156845 (rank : 123)
Query Neighborhood Hits	255	Target Neighborhood Hits	1480	Shared Neighborhood Hits	127
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CENPF_HUMAN
θ value	0.00665767 (rank : 83)	NC score	0.146673 (rank : 148)
Query Neighborhood Hits	255	Target Neighborhood Hits	1932	Shared Neighborhood Hits	142
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

MACF1_HUMAN
θ value	0.00665767 (rank : 84)	NC score	0.218982 (rank : 86)
Query Neighborhood Hits	255	Target Neighborhood Hits	1341	Shared Neighborhood Hits	139
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF4_HUMAN
θ value	0.00665767 (rank : 85)	NC score	0.212260 (rank : 88)
Query Neighborhood Hits	255	Target Neighborhood Hits	1321	Shared Neighborhood Hits	139
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

SYNE1_HUMAN
θ value	0.00665767 (rank : 86)	NC score	0.212760 (rank : 87)
Query Neighborhood Hits	255	Target Neighborhood Hits	1484	Shared Neighborhood Hits	143
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

ABR_HUMAN
θ value	0.0113563 (rank : 87)	NC score	0.313710 (rank : 70)
Query Neighborhood Hits	255	Target Neighborhood Hits	166	Shared Neighborhood Hits	62
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

ACTN2_HUMAN
θ value	0.0113563 (rank : 88)	NC score	0.182544 (rank : 103)
Query Neighborhood Hits	255	Target Neighborhood Hits	295	Shared Neighborhood Hits	64
SwissProt Accessions	P35609, Q86TF4, Q86TI8	Gene names	ACTN2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

ARHG2_HUMAN
θ value	0.0113563 (rank : 89)	NC score	0.400964 (rank : 59)
Query Neighborhood Hits	255	Target Neighborhood Hits	142	Shared Neighborhood Hits	71
SwissProt Accessions	Q92974, O75142, Q15079	Gene names	ARHGEF2, KIAA0651, LFP40
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (GEF-H1 protein) (Proliferating cell nucleolar antigen p40).

FGD5_MOUSE
θ value	0.0113563 (rank : 90)	NC score	0.358037 (rank : 64)
Query Neighborhood Hits	255	Target Neighborhood Hits	170	Shared Neighborhood Hits	54
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

PPIP1_HUMAN
θ value	0.0148317 (rank : 91)	NC score	0.172576 (rank : 111)
Query Neighborhood Hits	255	Target Neighborhood Hits	389	Shared Neighborhood Hits	85
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

SPTB2_HUMAN
θ value	0.0148317 (rank : 92)	NC score	0.240979 (rank : 78)
Query Neighborhood Hits	255	Target Neighborhood Hits	748	Shared Neighborhood Hits	126
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

BCR_HUMAN
θ value	0.0193708 (rank : 93)	NC score	0.307327 (rank : 72)
Query Neighborhood Hits	255	Target Neighborhood Hits	204	Shared Neighborhood Hits	62
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

PTN23_HUMAN
θ value	0.0330416 (rank : 94)	NC score	0.037848 (rank : 871)
Query Neighborhood Hits	255	Target Neighborhood Hits	646	Shared Neighborhood Hits	63
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

CI009_HUMAN
θ value	0.0431538 (rank : 95)	NC score	0.069631 (rank : 639)
Query Neighborhood Hits	255	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q96E40, Q9UGQ0	Gene names	C9orf9
Domain Architecture	No domain graphic available
Description	Protein C9orf9.

EEA1_HUMAN
θ value	0.0431538 (rank : 96)	NC score	0.174808 (rank : 109)
Query Neighborhood Hits	255	Target Neighborhood Hits	1796	Shared Neighborhood Hits	152
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

GCC2_HUMAN
θ value	0.0431538 (rank : 97)	NC score	0.140793 (rank : 155)
Query Neighborhood Hits	255	Target Neighborhood Hits	1558	Shared Neighborhood Hits	130
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

KIF5A_HUMAN
θ value	0.0431538 (rank : 98)	NC score	0.090650 (rank : 451)
Query Neighborhood Hits	255	Target Neighborhood Hits	843	Shared Neighborhood Hits	115
SwissProt Accessions	Q12840, Q4LE26	Gene names	KIF5A, NKHC1
Domain Architecture
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

RBP24_HUMAN
θ value	0.0431538 (rank : 99)	NC score	0.140165 (rank : 157)
Query Neighborhood Hits	255	Target Neighborhood Hits	1559	Shared Neighborhood Hits	129
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

REST_HUMAN
θ value	0.0431538 (rank : 100)	NC score	0.129397 (rank : 180)
Query Neighborhood Hits	255	Target Neighborhood Hits	1605	Shared Neighborhood Hits	132
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

SPTB2_MOUSE
θ value	0.0431538 (rank : 101)	NC score	0.239203 (rank : 79)
Query Neighborhood Hits	255	Target Neighborhood Hits	770	Shared Neighborhood Hits	122
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

ACTN4_MOUSE
θ value	0.0563607 (rank : 102)	NC score	0.186784 (rank : 95)
Query Neighborhood Hits	255	Target Neighborhood Hits	276	Shared Neighborhood Hits	68
SwissProt Accessions	P57780	Gene names	Actn4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

ARHG2_MOUSE
θ value	0.0563607 (rank : 103)	NC score	0.418452 (rank : 53)
Query Neighborhood Hits	255	Target Neighborhood Hits	120	Shared Neighborhood Hits	68
SwissProt Accessions	Q60875, O09115	Gene names	Arhgef2, Lbcl1, Lfc
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (Lymphoid blast crisis- like 1) (LBC'S first cousin) (Oncogene LFC) (RHOBIN).

ARHG5_HUMAN
θ value	0.0563607 (rank : 104)	NC score	0.476466 (rank : 45)
Query Neighborhood Hits	255	Target Neighborhood Hits	172	Shared Neighborhood Hits	80
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

ECT2_MOUSE
θ value	0.0563607 (rank : 105)	NC score	0.528228 (rank : 29)
Query Neighborhood Hits	255	Target Neighborhood Hits	98	Shared Neighborhood Hits	71
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

LIPA2_MOUSE
θ value	0.0563607 (rank : 106)	NC score	0.115217 (rank : 254)
Query Neighborhood Hits	255	Target Neighborhood Hits	1282	Shared Neighborhood Hits	118
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

LYN_HUMAN
θ value	0.0563607 (rank : 107)	NC score	0.043988 (rank : 865)
Query Neighborhood Hits	255	Target Neighborhood Hits	1022	Shared Neighborhood Hits	52
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

MACF1_MOUSE
θ value	0.0563607 (rank : 108)	NC score	0.212181 (rank : 89)
Query Neighborhood Hits	255	Target Neighborhood Hits	1313	Shared Neighborhood Hits	133
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

FGD5_HUMAN
θ value	0.0736092 (rank : 109)	NC score	0.368354 (rank : 63)
Query Neighborhood Hits	255	Target Neighborhood Hits	235	Shared Neighborhood Hits	57
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

LRSM1_HUMAN
θ value	0.0736092 (rank : 110)	NC score	0.076736 (rank : 576)
Query Neighborhood Hits	255	Target Neighborhood Hits	1078	Shared Neighborhood Hits	110
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

ARHG1_MOUSE
θ value	0.0961366 (rank : 111)	NC score	0.399912 (rank : 60)
Query Neighborhood Hits	255	Target Neighborhood Hits	266	Shared Neighborhood Hits	68
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

HOOK2_MOUSE
θ value	0.0961366 (rank : 112)	NC score	0.120119 (rank : 227)
Query Neighborhood Hits	255	Target Neighborhood Hits	736	Shared Neighborhood Hits	103
SwissProt Accessions	Q7TMK6, Q8BY47, Q8R347, Q8VCN4, Q99LU2	Gene names	Hook2
Domain Architecture
Description	Hook homolog 2.

KIF5A_MOUSE
θ value	0.0961366 (rank : 113)	NC score	0.087874 (rank : 478)
Query Neighborhood Hits	255	Target Neighborhood Hits	859	Shared Neighborhood Hits	116
SwissProt Accessions	P33175, Q5DTP1, Q6PDY7, Q9Z2F9	Gene names	Kif5a, Kiaa4086, Kif5, Nkhc1
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

LIPA3_HUMAN
θ value	0.0961366 (rank : 114)	NC score	0.101464 (rank : 346)
Query Neighborhood Hits	255	Target Neighborhood Hits	828	Shared Neighborhood Hits	103
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

MYH8_HUMAN
θ value	0.0961366 (rank : 115)	NC score	0.106076 (rank : 313)
Query Neighborhood Hits	255	Target Neighborhood Hits	1610	Shared Neighborhood Hits	136
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH8_MOUSE
θ value	0.0961366 (rank : 116)	NC score	0.105803 (rank : 317)
Query Neighborhood Hits	255	Target Neighborhood Hits	1600	Shared Neighborhood Hits	137
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

BCAR1_HUMAN
θ value	0.125558 (rank : 117)	NC score	0.122416 (rank : 212)
Query Neighborhood Hits	255	Target Neighborhood Hits	554	Shared Neighborhood Hits	51
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CK5P2_MOUSE
θ value	0.125558 (rank : 118)	NC score	0.126595 (rank : 193)
Query Neighborhood Hits	255	Target Neighborhood Hits	1151	Shared Neighborhood Hits	115
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

EVPL_MOUSE
θ value	0.125558 (rank : 119)	NC score	0.145747 (rank : 150)
Query Neighborhood Hits	255	Target Neighborhood Hits	952	Shared Neighborhood Hits	112
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

LYN_MOUSE
θ value	0.125558 (rank : 120)	NC score	0.042767 (rank : 868)
Query Neighborhood Hits	255	Target Neighborhood Hits	1023	Shared Neighborhood Hits	49
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

ACTN4_HUMAN
θ value	0.163984 (rank : 121)	NC score	0.183498 (rank : 101)
Query Neighborhood Hits	255	Target Neighborhood Hits	279	Shared Neighborhood Hits	67
SwissProt Accessions	O43707, O76048	Gene names	ACTN4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

GOGA3_MOUSE
θ value	0.163984 (rank : 122)	NC score	0.143497 (rank : 153)
Query Neighborhood Hits	255	Target Neighborhood Hits	1437	Shared Neighborhood Hits	134
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

PEPL_HUMAN
θ value	0.163984 (rank : 123)	NC score	0.147497 (rank : 145)
Query Neighborhood Hits	255	Target Neighborhood Hits	1141	Shared Neighborhood Hits	117
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

ACTN3_MOUSE
θ value	0.21417 (rank : 124)	NC score	0.185247 (rank : 98)
Query Neighborhood Hits	255	Target Neighborhood Hits	265	Shared Neighborhood Hits	67
SwissProt Accessions	O88990	Gene names	Actn3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

BCAR1_MOUSE
θ value	0.21417 (rank : 125)	NC score	0.126546 (rank : 194)
Query Neighborhood Hits	255	Target Neighborhood Hits	438	Shared Neighborhood Hits	52
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CK5P2_HUMAN
θ value	0.21417 (rank : 126)	NC score	0.121127 (rank : 221)
Query Neighborhood Hits	255	Target Neighborhood Hits	1433	Shared Neighborhood Hits	126
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

ECT2_HUMAN
θ value	0.21417 (rank : 127)	NC score	0.512861 (rank : 35)
Query Neighborhood Hits	255	Target Neighborhood Hits	98	Shared Neighborhood Hits	71
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

FYCO1_MOUSE
θ value	0.21417 (rank : 128)	NC score	0.156523 (rank : 124)
Query Neighborhood Hits	255	Target Neighborhood Hits	1059	Shared Neighborhood Hits	131
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

HOOK2_HUMAN
θ value	0.21417 (rank : 129)	NC score	0.113118 (rank : 265)
Query Neighborhood Hits	255	Target Neighborhood Hits	714	Shared Neighborhood Hits	104
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

KTN1_MOUSE
θ value	0.21417 (rank : 130)	NC score	0.137295 (rank : 161)
Query Neighborhood Hits	255	Target Neighborhood Hits	1324	Shared Neighborhood Hits	133
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

MYH2_HUMAN
θ value	0.21417 (rank : 131)	NC score	0.104374 (rank : 328)
Query Neighborhood Hits	255	Target Neighborhood Hits	1491	Shared Neighborhood Hits	133
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

PEPL_MOUSE
θ value	0.21417 (rank : 132)	NC score	0.151605 (rank : 132)
Query Neighborhood Hits	255	Target Neighborhood Hits	1105	Shared Neighborhood Hits	123
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

PRP31_HUMAN
θ value	0.21417 (rank : 133)	NC score	0.045463 (rank : 861)
Query Neighborhood Hits	255	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WWY3, Q8N7F9, Q9H271, Q9Y439	Gene names	PRPF31, PRP31
Domain Architecture	No domain graphic available
Description	U4/U6 small nuclear ribonucleoprotein Prp31 (Pre-mRNA-processing factor 31) (U4/U6 snRNP 61 kDa protein) (hPrp31) (Protein 61K) (Serologically defined breast cancer antigen NY-BR-99).

SPTN2_HUMAN
θ value	0.21417 (rank : 134)	NC score	0.222447 (rank : 84)
Query Neighborhood Hits	255	Target Neighborhood Hits	535	Shared Neighborhood Hits	101
SwissProt Accessions	O15020, O14872, O14873	Gene names	SPTBN2, KIAA0302
Domain Architecture
Description	Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).

SWP70_MOUSE
θ value	0.21417 (rank : 135)	NC score	0.124482 (rank : 204)
Query Neighborhood Hits	255	Target Neighborhood Hits	1097	Shared Neighborhood Hits	126
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

CCD21_MOUSE
θ value	0.279714 (rank : 136)	NC score	0.111027 (rank : 284)
Query Neighborhood Hits	255	Target Neighborhood Hits	1135	Shared Neighborhood Hits	122
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

GOGA4_MOUSE
θ value	0.279714 (rank : 137)	NC score	0.138421 (rank : 159)
Query Neighborhood Hits	255	Target Neighborhood Hits	1939	Shared Neighborhood Hits	138
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

LAMB1_HUMAN
θ value	0.279714 (rank : 138)	NC score	0.055074 (rank : 794)
Query Neighborhood Hits	255	Target Neighborhood Hits	1018	Shared Neighborhood Hits	97
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LIPA2_HUMAN
θ value	0.279714 (rank : 139)	NC score	0.118921 (rank : 233)
Query Neighborhood Hits	255	Target Neighborhood Hits	1044	Shared Neighborhood Hits	109
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

NIN_MOUSE
θ value	0.279714 (rank : 140)	NC score	0.126847 (rank : 190)
Query Neighborhood Hits	255	Target Neighborhood Hits	1376	Shared Neighborhood Hits	123
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

TAXB1_MOUSE
θ value	0.279714 (rank : 141)	NC score	0.112424 (rank : 274)
Query Neighborhood Hits	255	Target Neighborhood Hits	886	Shared Neighborhood Hits	102
SwissProt Accessions	Q3UKC1, Q91YT6, Q9CVF0, Q9DC45	Gene names	Tax1bp1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 homolog.

CP135_MOUSE
θ value	0.365318 (rank : 142)	NC score	0.131137 (rank : 171)
Query Neighborhood Hits	255	Target Neighborhood Hits	1278	Shared Neighborhood Hits	123
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

ADDB_MOUSE
θ value	0.47712 (rank : 143)	NC score	0.016705 (rank : 897)
Query Neighborhood Hits	255	Target Neighborhood Hits	574	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

CENPE_HUMAN
θ value	0.47712 (rank : 144)	NC score	0.130241 (rank : 173)
Query Neighborhood Hits	255	Target Neighborhood Hits	2060	Shared Neighborhood Hits	147
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CI009_MOUSE
θ value	0.47712 (rank : 145)	NC score	0.059000 (rank : 759)
Query Neighborhood Hits	255	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TPM5, Q3U293, Q9D9W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C9orf9 homolog.

DNMT1_HUMAN
θ value	0.47712 (rank : 146)	NC score	0.027793 (rank : 880)
Query Neighborhood Hits	255	Target Neighborhood Hits	401	Shared Neighborhood Hits	27
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

EVPL_HUMAN
θ value	0.47712 (rank : 147)	NC score	0.151216 (rank : 136)
Query Neighborhood Hits	255	Target Neighborhood Hits	895	Shared Neighborhood Hits	117
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

GOGA1_HUMAN
θ value	0.47712 (rank : 148)	NC score	0.129281 (rank : 181)
Query Neighborhood Hits	255	Target Neighborhood Hits	1222	Shared Neighborhood Hits	129
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

IQGA3_HUMAN
θ value	0.47712 (rank : 149)	NC score	0.043461 (rank : 867)
Query Neighborhood Hits	255	Target Neighborhood Hits	125	Shared Neighborhood Hits	26
SwissProt Accessions	Q86VI3	Gene names	IQGAP3
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP3.

KI21A_HUMAN
θ value	0.47712 (rank : 150)	NC score	0.083781 (rank : 526)
Query Neighborhood Hits	255	Target Neighborhood Hits	1543	Shared Neighborhood Hits	115
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

MRCKA_HUMAN
θ value	0.47712 (rank : 151)	NC score	0.078406 (rank : 563)
Query Neighborhood Hits	255	Target Neighborhood Hits	1999	Shared Neighborhood Hits	147
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

PRP31_MOUSE
θ value	0.47712 (rank : 152)	NC score	0.042593 (rank : 869)
Query Neighborhood Hits	255	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CCF0, Q6P7X2, Q8BQ91, Q8C8U4, Q8C8V5, Q8CCG6, Q8CF52, Q8VBW3	Gene names	Prpf31, Prp31
Domain Architecture	No domain graphic available
Description	U4/U6 small nuclear ribonucleoprotein Prp31 (Pre-mRNA-processing factor 31) (U4/U6 snRNP 61 kDa protein) (Protein 61K).

GOGA4_HUMAN
θ value	0.62314 (rank : 153)	NC score	0.147494 (rank : 146)
Query Neighborhood Hits	255	Target Neighborhood Hits	2034	Shared Neighborhood Hits	147
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

KI21B_HUMAN
θ value	0.62314 (rank : 154)	NC score	0.068267 (rank : 653)
Query Neighborhood Hits	255	Target Neighborhood Hits	1017	Shared Neighborhood Hits	104
SwissProt Accessions	O75037, Q5T4J3	Gene names	KIF21B, KIAA0449
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B.

KI21B_MOUSE
θ value	0.62314 (rank : 155)	NC score	0.067610 (rank : 658)
Query Neighborhood Hits	255	Target Neighborhood Hits	997	Shared Neighborhood Hits	100
SwissProt Accessions	Q9QXL1, P97424	Gene names	Kif21b, Kif6
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B (Kinesin-like protein KIF6).

KIF3C_HUMAN
θ value	0.62314 (rank : 156)	NC score	0.055016 (rank : 795)
Query Neighborhood Hits	255	Target Neighborhood Hits	478	Shared Neighborhood Hits	85
SwissProt Accessions	O14782, O43544	Gene names	KIF3C
Domain Architecture
Description	Kinesin-like protein KIF3C.

MATK_MOUSE
θ value	0.62314 (rank : 157)	NC score	0.032596 (rank : 873)
Query Neighborhood Hits	255	Target Neighborhood Hits	952	Shared Neighborhood Hits	37
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

SYNE2_HUMAN
θ value	0.62314 (rank : 158)	NC score	0.196845 (rank : 92)
Query Neighborhood Hits	255	Target Neighborhood Hits	1323	Shared Neighborhood Hits	134
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

TRIPB_HUMAN
θ value	0.62314 (rank : 159)	NC score	0.148331 (rank : 142)
Query Neighborhood Hits	255	Target Neighborhood Hits	1587	Shared Neighborhood Hits	141
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

M3K9_HUMAN
θ value	0.813845 (rank : 160)	NC score	0.053384 (rank : 815)
Query Neighborhood Hits	255	Target Neighborhood Hits	1123	Shared Neighborhood Hits	71
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

MRCKB_HUMAN
θ value	0.813845 (rank : 161)	NC score	0.083644 (rank : 527)
Query Neighborhood Hits	255	Target Neighborhood Hits	2239	Shared Neighborhood Hits	152
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

RB6I2_HUMAN
θ value	0.813845 (rank : 162)	NC score	0.122051 (rank : 216)
Query Neighborhood Hits	255	Target Neighborhood Hits	1584	Shared Neighborhood Hits	130
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

SDCG8_MOUSE
θ value	0.813845 (rank : 163)	NC score	0.113184 (rank : 263)
Query Neighborhood Hits	255	Target Neighborhood Hits	886	Shared Neighborhood Hits	110
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

CJ118_MOUSE
θ value	1.06291 (rank : 164)	NC score	0.122361 (rank : 214)
Query Neighborhood Hits	255	Target Neighborhood Hits	1132	Shared Neighborhood Hits	115
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

DTBP1_MOUSE
θ value	1.06291 (rank : 165)	NC score	0.063851 (rank : 697)
Query Neighborhood Hits	255	Target Neighborhood Hits	209	Shared Neighborhood Hits	48
SwissProt Accessions	Q91WZ8, Q80ZN4	Gene names	Dtnbp1
Domain Architecture
Description	Dystrobrevin-binding protein 1 (Dysbindin) (Hermansky-Pudlak syndrome 7 protein homolog).

HCK_MOUSE
θ value	1.06291 (rank : 166)	NC score	0.044798 (rank : 863)
Query Neighborhood Hits	255	Target Neighborhood Hits	1029	Shared Neighborhood Hits	56
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

JIP3_HUMAN
θ value	1.06291 (rank : 167)	NC score	0.086647 (rank : 493)
Query Neighborhood Hits	255	Target Neighborhood Hits	1039	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

JIP3_MOUSE
θ value	1.06291 (rank : 168)	NC score	0.091379 (rank : 444)
Query Neighborhood Hits	255	Target Neighborhood Hits	759	Shared Neighborhood Hits	98
SwissProt Accessions	Q9ESN9, Q99KU7, Q9EQD8, Q9ESN7, Q9ESN8, Q9ESP0, Q9JLH2, Q9JLH3, Q9R0U7	Gene names	Mapk8ip3, Jip3, Jsap1, Syd2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3) (JNK/SAPK-associated protein 1) (JSAP1) (Sunday driver 2).

M3K11_HUMAN
θ value	1.06291 (rank : 169)	NC score	0.052017 (rank : 834)
Query Neighborhood Hits	255	Target Neighborhood Hits	1136	Shared Neighborhood Hits	67
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

MICA2_HUMAN
θ value	1.06291 (rank : 170)	NC score	0.085775 (rank : 506)
Query Neighborhood Hits	255	Target Neighborhood Hits	174	Shared Neighborhood Hits	26
SwissProt Accessions	O94851, Q7Z3A8	Gene names	MICAL2, KIAA0750
Domain Architecture
Description	Protein MICAL-2.

PPIP1_MOUSE
θ value	1.06291 (rank : 171)	NC score	0.161563 (rank : 114)
Query Neighborhood Hits	255	Target Neighborhood Hits	377	Shared Neighborhood Hits	83
SwissProt Accessions	P97814, Q4V9R4	Gene names	Pstpip1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1).

CCG3_MOUSE
θ value	1.38821 (rank : 172)	NC score	0.016912 (rank : 895)
Query Neighborhood Hits	255	Target Neighborhood Hits	38	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JJV5	Gene names	Cacng3
Domain Architecture
Description	Voltage-dependent calcium channel gamma-3 subunit (Neuronal voltage- gated calcium channel gamma-3 subunit).

CENG2_HUMAN
θ value	1.38821 (rank : 173)	NC score	0.008050 (rank : 905)
Query Neighborhood Hits	255	Target Neighborhood Hits	471	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

CR034_MOUSE
θ value	1.38821 (rank : 174)	NC score	0.121453 (rank : 218)
Query Neighborhood Hits	255	Target Neighborhood Hits	643	Shared Neighborhood Hits	102
SwissProt Accessions	Q8CDV0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34 homolog.

GBX1_HUMAN
θ value	1.38821 (rank : 175)	NC score	0.003843 (rank : 907)
Query Neighborhood Hits	255	Target Neighborhood Hits	334	Shared Neighborhood Hits	6
SwissProt Accessions	Q14549	Gene names	GBX1
Domain Architecture	No domain graphic available
Description	Homeobox protein GBX-1 (Gastrulation and brain-specific homeobox protein 1).

HCK_HUMAN
θ value	1.38821 (rank : 176)	NC score	0.044958 (rank : 862)
Query Neighborhood Hits	255	Target Neighborhood Hits	1035	Shared Neighborhood Hits	54
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

IQGA1_HUMAN
θ value	1.38821 (rank : 177)	NC score	0.057527 (rank : 774)
Query Neighborhood Hits	255	Target Neighborhood Hits	250	Shared Neighborhood Hits	53
SwissProt Accessions	P46940	Gene names	IQGAP1, KIAA0051
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1 (p195).

TUFT1_HUMAN
θ value	1.38821 (rank : 178)	NC score	0.109607 (rank : 292)
Query Neighborhood Hits	255	Target Neighborhood Hits	686	Shared Neighborhood Hits	104
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

CF146_MOUSE
θ value	1.81305 (rank : 179)	NC score	0.028200 (rank : 879)
Query Neighborhood Hits	255	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D9W6	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf146 homolog.

CP250_HUMAN
θ value	1.81305 (rank : 180)	NC score	0.143209 (rank : 154)
Query Neighborhood Hits	255	Target Neighborhood Hits	1805	Shared Neighborhood Hits	141
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

CROCC_HUMAN
θ value	1.81305 (rank : 181)	NC score	0.127736 (rank : 188)
Query Neighborhood Hits	255	Target Neighborhood Hits	1409	Shared Neighborhood Hits	130
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CROCC_MOUSE
θ value	1.81305 (rank : 182)	NC score	0.128078 (rank : 185)
Query Neighborhood Hits	255	Target Neighborhood Hits	1460	Shared Neighborhood Hits	132
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

DMD_MOUSE
θ value	1.81305 (rank : 183)	NC score	0.191300 (rank : 94)
Query Neighborhood Hits	255	Target Neighborhood Hits	1111	Shared Neighborhood Hits	129
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

KI21A_MOUSE
θ value	1.81305 (rank : 184)	NC score	0.081133 (rank : 545)
Query Neighborhood Hits	255	Target Neighborhood Hits	1317	Shared Neighborhood Hits	112
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

KIF3C_MOUSE
θ value	1.81305 (rank : 185)	NC score	0.055503 (rank : 788)
Query Neighborhood Hits	255	Target Neighborhood Hits	468	Shared Neighborhood Hits	86
SwissProt Accessions	O35066, O35229	Gene names	Kif3c
Domain Architecture
Description	Kinesin-like protein KIF3C.

KS6B1_HUMAN
θ value	1.81305 (rank : 186)	NC score	0.020573 (rank : 888)
Query Neighborhood Hits	255	Target Neighborhood Hits	850	Shared Neighborhood Hits	23
SwissProt Accessions	P23443	Gene names	RPS6KB1
Domain Architecture
Description	Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1) (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) (p70-S6K) (P70S6K) (p70-alpha).

CCG3_HUMAN
θ value	2.36792 (rank : 187)	NC score	0.015440 (rank : 900)
Query Neighborhood Hits	255	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	O60359	Gene names	CACNG3
Domain Architecture
Description	Voltage-dependent calcium channel gamma-3 subunit (Neuronal voltage- gated calcium channel gamma-3 subunit).

CP250_MOUSE
θ value	2.36792 (rank : 188)	NC score	0.144198 (rank : 152)
Query Neighborhood Hits	255	Target Neighborhood Hits	1583	Shared Neighborhood Hits	140
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

FRK_HUMAN
θ value	2.36792 (rank : 189)	NC score	0.044199 (rank : 864)
Query Neighborhood Hits	255	Target Neighborhood Hits	1058	Shared Neighborhood Hits	58
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

MYH13_HUMAN
θ value	2.36792 (rank : 190)	NC score	0.102028 (rank : 342)
Query Neighborhood Hits	255	Target Neighborhood Hits	1504	Shared Neighborhood Hits	133
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

MYH3_HUMAN
θ value	2.36792 (rank : 191)	NC score	0.106022 (rank : 314)
Query Neighborhood Hits	255	Target Neighborhood Hits	1660	Shared Neighborhood Hits	134
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

SIL1_MOUSE
θ value	2.36792 (rank : 192)	NC score	0.029061 (rank : 878)
Query Neighborhood Hits	255	Target Neighborhood Hits	68	Shared Neighborhood Hits	16
SwissProt Accessions	Q9EPK6, Q91V34	Gene names	Sil1
Domain Architecture	No domain graphic available
Description	Nucleotide exchange factor SIL1 precursor.

AHTF1_HUMAN
θ value	3.0926 (rank : 193)	NC score	0.027425 (rank : 882)
Query Neighborhood Hits	255	Target Neighborhood Hits	286	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WYP5, Q7Z4E3, Q8IZA4, Q96EH9, Q9Y4Q6	Gene names	AHCTF1, ELYS, TMBS62
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

BLK_HUMAN
θ value	3.0926 (rank : 194)	NC score	0.043529 (rank : 866)
Query Neighborhood Hits	255	Target Neighborhood Hits	994	Shared Neighborhood Hits	51
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

CAF1A_HUMAN
θ value	3.0926 (rank : 195)	NC score	0.076006 (rank : 583)
Query Neighborhood Hits	255	Target Neighborhood Hits	750	Shared Neighborhood Hits	85
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

FYN_HUMAN
θ value	3.0926 (rank : 196)	NC score	0.050901 (rank : 849)
Query Neighborhood Hits	255	Target Neighborhood Hits	1078	Shared Neighborhood Hits	55
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

FYN_MOUSE
θ value	3.0926 (rank : 197)	NC score	0.052667 (rank : 824)
Query Neighborhood Hits	255	Target Neighborhood Hits	1073	Shared Neighborhood Hits	55
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

LRSM1_MOUSE
θ value	3.0926 (rank : 198)	NC score	0.063899 (rank : 696)
Query Neighborhood Hits	255	Target Neighborhood Hits	874	Shared Neighborhood Hits	83
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

NEMO_MOUSE
θ value	3.0926 (rank : 199)	NC score	0.098486 (rank : 366)
Query Neighborhood Hits	255	Target Neighborhood Hits	658	Shared Neighborhood Hits	104
SwissProt Accessions	O88522	Gene names	Ikbkg, Nemo
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (mFIP-3).

PCNT_HUMAN
θ value	3.0926 (rank : 200)	NC score	0.126009 (rank : 196)
Query Neighborhood Hits	255	Target Neighborhood Hits	1551	Shared Neighborhood Hits	132
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

PLEC1_HUMAN
θ value	3.0926 (rank : 201)	NC score	0.177986 (rank : 108)
Query Neighborhood Hits	255	Target Neighborhood Hits	1326	Shared Neighborhood Hits	129
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

PTN23_MOUSE
θ value	3.0926 (rank : 202)	NC score	0.033918 (rank : 872)
Query Neighborhood Hits	255	Target Neighborhood Hits	726	Shared Neighborhood Hits	67
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

SYCP3_HUMAN
θ value	3.0926 (rank : 203)	NC score	0.046760 (rank : 859)
Query Neighborhood Hits	255	Target Neighborhood Hits	276	Shared Neighborhood Hits	45
SwissProt Accessions	Q8IZU3	Gene names	SYCP3, SCP3
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 3 (SCP-3).

TOM70_HUMAN
θ value	3.0926 (rank : 204)	NC score	0.008583 (rank : 904)
Query Neighborhood Hits	255	Target Neighborhood Hits	127	Shared Neighborhood Hits	3
SwissProt Accessions	O94826	Gene names	TOMM70A, KIAA0719
Domain Architecture
Description	Mitochondrial precursor proteins import receptor (Translocase of outer membrane TOM70).

C8AP2_HUMAN
θ value	4.03905 (rank : 205)	NC score	0.032223 (rank : 874)
Query Neighborhood Hits	255	Target Neighborhood Hits	548	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

CASL_HUMAN
θ value	4.03905 (rank : 206)	NC score	0.112144 (rank : 275)
Query Neighborhood Hits	255	Target Neighborhood Hits	259	Shared Neighborhood Hits	45
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

CASL_MOUSE
θ value	4.03905 (rank : 207)	NC score	0.108196 (rank : 298)
Query Neighborhood Hits	255	Target Neighborhood Hits	225	Shared Neighborhood Hits	40
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

DDX24_HUMAN
θ value	4.03905 (rank : 208)	NC score	0.002918 (rank : 909)
Query Neighborhood Hits	255	Target Neighborhood Hits	190	Shared Neighborhood Hits	3
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

HDAC9_HUMAN
θ value	4.03905 (rank : 209)	NC score	0.023189 (rank : 885)
Query Neighborhood Hits	255	Target Neighborhood Hits	201	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UKV0, O94845, O95028	Gene names	HDAC9, HDAC7, HDAC7B, KIAA0744
Domain Architecture
Description	Histone deacetylase 9 (HD9) (HD7B) (HD7).

K0999_MOUSE
θ value	4.03905 (rank : 210)	NC score	0.023304 (rank : 884)
Query Neighborhood Hits	255	Target Neighborhood Hits	931	Shared Neighborhood Hits	28
SwissProt Accessions	Q6P4S6, Q641L5, Q66JZ5, Q6ZQ09, Q8K075, Q9CYD5	Gene names	Kiaa0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).

NIN_HUMAN
θ value	4.03905 (rank : 211)	NC score	0.131793 (rank : 167)
Query Neighborhood Hits	255	Target Neighborhood Hits	1416	Shared Neighborhood Hits	126
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

TXLNB_HUMAN
θ value	4.03905 (rank : 212)	NC score	0.080212 (rank : 551)
Query Neighborhood Hits	255	Target Neighborhood Hits	912	Shared Neighborhood Hits	93
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

CALB1_HUMAN
θ value	5.27518 (rank : 213)	NC score	0.020786 (rank : 887)
Query Neighborhood Hits	255	Target Neighborhood Hits	130	Shared Neighborhood Hits	12
SwissProt Accessions	P05937	Gene names	CALB1, CAB27
Domain Architecture
Description	Calbindin (Vitamin D-dependent calcium-binding protein, avian-type) (Calbindin D28) (D-28K).

CALB1_MOUSE
θ value	5.27518 (rank : 214)	NC score	0.018250 (rank : 892)
Query Neighborhood Hits	255	Target Neighborhood Hits	129	Shared Neighborhood Hits	9
SwissProt Accessions	P12658, Q545N6	Gene names	Calb1
Domain Architecture
Description	Calbindin (Vitamin D-dependent calcium-binding protein, avian-type) (Calbindin D28) (D-28K) (Spot 35 protein) (PCD-29).

DPOD3_MOUSE
θ value	5.27518 (rank : 215)	NC score	0.013977 (rank : 901)
Query Neighborhood Hits	255	Target Neighborhood Hits	118	Shared Neighborhood Hits	6
SwissProt Accessions	Q9EQ28	Gene names	Pold3
Domain Architecture	No domain graphic available
Description	DNA polymerase subunit delta 3 (DNA polymerase subunit delta p66).

GBX1_MOUSE
θ value	5.27518 (rank : 216)	NC score	0.002023 (rank : 910)
Query Neighborhood Hits	255	Target Neighborhood Hits	350	Shared Neighborhood Hits	6
SwissProt Accessions	P82976, Q8CGW5	Gene names	Gbx1
Domain Architecture	No domain graphic available
Description	Homeobox protein GBX-1 (Gastrulation and brain-specific homeobox protein 1).

GP151_MOUSE
θ value	5.27518 (rank : 217)	NC score	0.003305 (rank : 908)
Query Neighborhood Hits	255	Target Neighborhood Hits	248	Shared Neighborhood Hits	2
SwissProt Accessions	Q7TSN6, Q80UD8, Q8BX88	Gene names	Gpr151, Pgr7
Domain Architecture
Description	Probable G-protein coupled receptor 151 protein (G-protein coupled receptor PGR7) (GPCR-2037).

LAMA3_HUMAN
θ value	5.27518 (rank : 218)	NC score	0.055940 (rank : 787)
Query Neighborhood Hits	255	Target Neighborhood Hits	760	Shared Neighborhood Hits	89
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

MAGI1_MOUSE
θ value	5.27518 (rank : 219)	NC score	0.009010 (rank : 903)
Query Neighborhood Hits	255	Target Neighborhood Hits	403	Shared Neighborhood Hits	10
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

MPP2_MOUSE
θ value	5.27518 (rank : 220)	NC score	0.016828 (rank : 896)
Query Neighborhood Hits	255	Target Neighborhood Hits	189	Shared Neighborhood Hits	21
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

MYH10_MOUSE
θ value	5.27518 (rank : 221)	NC score	0.108719 (rank : 295)
Query Neighborhood Hits	255	Target Neighborhood Hits	1612	Shared Neighborhood Hits	140
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

NOL8_HUMAN
θ value	5.27518 (rank : 222)	NC score	0.017891 (rank : 893)
Query Neighborhood Hits	255	Target Neighborhood Hits	297	Shared Neighborhood Hits	15
SwissProt Accessions	Q76FK4, Q5TCC7, Q5TCC8, Q5TCD3, Q5TCD5, Q5TCD6, Q5TCD7, Q76D35, Q7L3E2, Q9H586, Q9H795, Q9H7W7, Q9H9J6, Q9NWA4, Q9NWM4	Gene names	NOL8, NOP132
Domain Architecture	No domain graphic available
Description	Nucleolar protein 8 (Nucleolar protein Nop132).

NOL8_MOUSE
θ value	5.27518 (rank : 223)	NC score	0.022601 (rank : 886)
Query Neighborhood Hits	255	Target Neighborhood Hits	210	Shared Neighborhood Hits	17
SwissProt Accessions	Q3UHX0, Q504M4, Q8CDJ7, Q9CUR0	Gene names	Nol8
Domain Architecture	No domain graphic available
Description	Nucleolar protein 8.

RABE1_HUMAN
θ value	5.27518 (rank : 224)	NC score	0.119510 (rank : 228)
Query Neighborhood Hits	255	Target Neighborhood Hits	1104	Shared Neighborhood Hits	124
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

RB6I2_MOUSE
θ value	5.27518 (rank : 225)	NC score	0.121370 (rank : 219)
Query Neighborhood Hits	255	Target Neighborhood Hits	1433	Shared Neighborhood Hits	126
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

ROCK2_HUMAN
θ value	5.27518 (rank : 226)	NC score	0.074177 (rank : 599)
Query Neighborhood Hits	255	Target Neighborhood Hits	2073	Shared Neighborhood Hits	144
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

CCD91_MOUSE
θ value	6.88961 (rank : 227)	NC score	0.111984 (rank : 276)
Query Neighborhood Hits	255	Target Neighborhood Hits	699	Shared Neighborhood Hits	95
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

CD72_MOUSE
θ value	6.88961 (rank : 228)	NC score	0.045750 (rank : 860)
Query Neighborhood Hits	255	Target Neighborhood Hits	262	Shared Neighborhood Hits	53
SwissProt Accessions	P21855, Q64225	Gene names	Cd72, Ly-32, Lyb-2
Domain Architecture
Description	B-cell differentiation antigen CD72 (Lyb-2) (Antigen Ly-32).

CENG2_MOUSE
θ value	6.88961 (rank : 229)	NC score	0.005891 (rank : 906)
Query Neighborhood Hits	255	Target Neighborhood Hits	463	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

CJ118_HUMAN
θ value	6.88961 (rank : 230)	NC score	0.112643 (rank : 271)
Query Neighborhood Hits	255	Target Neighborhood Hits	937	Shared Neighborhood Hits	112
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

DCTN2_HUMAN
θ value	6.88961 (rank : 231)	NC score	0.029960 (rank : 877)
Query Neighborhood Hits	255	Target Neighborhood Hits	72	Shared Neighborhood Hits	23
SwissProt Accessions	Q13561, Q86YN2, Q9BW17	Gene names	DCTN2, DCTN50
Domain Architecture
Description	Dynactin subunit 2 (Dynactin complex 50 kDa subunit) (50 kDa dynein- associated polypeptide) (p50 dynamitin) (DCTN-50).

DLX3_HUMAN
θ value	6.88961 (rank : 232)	NC score	0.000761 (rank : 912)
Query Neighborhood Hits	255	Target Neighborhood Hits	369	Shared Neighborhood Hits	7
SwissProt Accessions	O60479	Gene names	DLX3
Domain Architecture
Description	Homeobox protein DLX-3.

DLX3_MOUSE
θ value	6.88961 (rank : 233)	NC score	0.001121 (rank : 911)
Query Neighborhood Hits	255	Target Neighborhood Hits	367	Shared Neighborhood Hits	8
SwissProt Accessions	Q64205	Gene names	Dlx3
Domain Architecture
Description	Homeobox protein DLX-3.

MYO5C_HUMAN
θ value	6.88961 (rank : 234)	NC score	0.079956 (rank : 555)
Query Neighborhood Hits	255	Target Neighborhood Hits	1206	Shared Neighborhood Hits	124
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

OLR1_MOUSE
θ value	6.88961 (rank : 235)	NC score	0.075074 (rank : 593)
Query Neighborhood Hits	255	Target Neighborhood Hits	596	Shared Neighborhood Hits	82
SwissProt Accessions	Q9EQ09	Gene names	Olr1, Lox1
Domain Architecture	No domain graphic available
Description	Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) (Lectin-type oxidized LDL receptor 1) (Lectin-like oxidized LDL receptor 1) (Lectin-like oxLDL receptor 1) (LOX-1) [Contains: Oxidized low-density lipoprotein receptor 1, soluble form].

PRRX2_HUMAN
θ value	6.88961 (rank : 236)	NC score	-0.000305 (rank : 914)
Query Neighborhood Hits	255	Target Neighborhood Hits	348	Shared Neighborhood Hits	6
SwissProt Accessions	Q99811, Q9UIB3	Gene names	PRRX2, PMX2, PRX2
Domain Architecture
Description	Paired mesoderm homeobox protein 2 (PRX-2) (Paired-related homeobox protein 2).

S3TC1_HUMAN
θ value	6.88961 (rank : 237)	NC score	0.026133 (rank : 883)
Query Neighborhood Hits	255	Target Neighborhood Hits	78	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TE82	Gene names	SH3TC1
Domain Architecture	No domain graphic available
Description	SH3 domain and tetratricopeptide repeats-containing protein 1.

SETX_HUMAN
θ value	6.88961 (rank : 238)	NC score	0.020007 (rank : 891)
Query Neighborhood Hits	255	Target Neighborhood Hits	368	Shared Neighborhood Hits	30
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

ZN445_MOUSE
θ value	6.88961 (rank : 239)	NC score	-0.008034 (rank : 915)
Query Neighborhood Hits	255	Target Neighborhood Hits	760	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R2V3, Q8K216	Gene names	Znf445, Zfp445
Domain Architecture
Description	Zinc finger protein 445.

ATF6B_MOUSE
θ value	8.99809 (rank : 240)	NC score	0.010458 (rank : 902)
Query Neighborhood Hits	255	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	O35451	Gene names	Crebl1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp).

CN145_MOUSE
θ value	8.99809 (rank : 241)	NC score	0.109350 (rank : 293)
Query Neighborhood Hits	255	Target Neighborhood Hits	916	Shared Neighborhood Hits	112
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

GRB2_HUMAN
θ value	8.99809 (rank : 242)	NC score	0.147982 (rank : 143)
Query Neighborhood Hits	255	Target Neighborhood Hits	310	Shared Neighborhood Hits	49
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
θ value	8.99809 (rank : 243)	NC score	0.147808 (rank : 144)
Query Neighborhood Hits	255	Target Neighborhood Hits	312	Shared Neighborhood Hits	49
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

HDAC9_MOUSE
θ value	8.99809 (rank : 244)	NC score	0.038336 (rank : 870)
Query Neighborhood Hits	255	Target Neighborhood Hits	186	Shared Neighborhood Hits	43
SwissProt Accessions	Q99N13, Q9EPT2	Gene names	Hdac9, Hdac7b, Hdrp, Mitr
Domain Architecture	No domain graphic available
Description	Histone deacetylase 9 (HD9) (HD7B) (Histone deacetylase-related protein) (MEF2-interacting transcription repressor MITR).

K1C18_HUMAN
θ value	8.99809 (rank : 245)	NC score	0.031370 (rank : 875)
Query Neighborhood Hits	255	Target Neighborhood Hits	441	Shared Neighborhood Hits	78
SwissProt Accessions	P05783, Q9BW26	Gene names	KRT18, CYK18
Domain Architecture
Description	Keratin, type I cytoskeletal 18 (Cytokeratin-18) (CK-18) (Keratin-18) (K18).

KGP1B_HUMAN
θ value	8.99809 (rank : 246)	NC score	0.020506 (rank : 890)
Query Neighborhood Hits	255	Target Neighborhood Hits	921	Shared Neighborhood Hits	34
SwissProt Accessions	P14619	Gene names	PRKG1, PRKG1B, PRKGR1B
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP1B_MOUSE
θ value	8.99809 (rank : 247)	NC score	0.020507 (rank : 889)
Query Neighborhood Hits	255	Target Neighborhood Hits	922	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Z0Z0	Gene names	Prkg1, Prkg1b, Prkgr1b
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KMHN1_MOUSE
θ value	8.99809 (rank : 248)	NC score	0.112750 (rank : 268)
Query Neighborhood Hits	255	Target Neighborhood Hits	949	Shared Neighborhood Hits	122
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

LAMC3_MOUSE
θ value	8.99809 (rank : 249)	NC score	0.015752 (rank : 898)
Query Neighborhood Hits	255	Target Neighborhood Hits	624	Shared Neighborhood Hits	54
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

MATK_HUMAN
θ value	8.99809 (rank : 250)	NC score	0.030765 (rank : 876)
Query Neighborhood Hits	255	Target Neighborhood Hits	954	Shared Neighborhood Hits	41
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

PROM1_MOUSE
θ value	8.99809 (rank : 251)	NC score	0.015518 (rank : 899)
Query Neighborhood Hits	255	Target Neighborhood Hits	77	Shared Neighborhood Hits	13
SwissProt Accessions	O54990, O35408	Gene names	Prom1, Prom, Proml1
Domain Architecture
Description	Prominin-1 precursor (Prominin-like protein 1) (Antigen AC133 homolog).

RBM19_MOUSE
θ value	8.99809 (rank : 252)	NC score	0.000586 (rank : 913)
Query Neighborhood Hits	255	Target Neighborhood Hits	296	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R3C6, Q8BHR0, Q9CW63	Gene names	Rbm19
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 19 (RNA-binding motif protein 19).

SDCG1_MOUSE
θ value	8.99809 (rank : 253)	NC score	0.017656 (rank : 894)
Query Neighborhood Hits	255	Target Neighborhood Hits	168	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CCP0, Q66JX6, Q8C9R6, Q8CA65, Q8JZT9, Q8R072, Q9CW30, Q9CYB8, Q9D4A9	Gene names	Sdccag1
Domain Architecture
Description	Serologically defined colon cancer antigen 1.

SFPQ_MOUSE
θ value	8.99809 (rank : 254)	NC score	0.027790 (rank : 881)
Query Neighborhood Hits	255	Target Neighborhood Hits	958	Shared Neighborhood Hits	60
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

ZN291_HUMAN
θ value	8.99809 (rank : 255)	NC score	0.105869 (rank : 315)
Query Neighborhood Hits	255	Target Neighborhood Hits	647	Shared Neighborhood Hits	101
SwissProt Accessions	Q9BY12	Gene names	ZNF291
Domain Architecture
Description	Zinc finger protein 291.

3BP5_HUMAN
θ value	θ > 10 (rank : 256)	NC score	0.064855 (rank : 684)
Query Neighborhood Hits	255	Target Neighborhood Hits	375	Shared Neighborhood Hits	75
SwissProt Accessions	O60239	Gene names	SH3BP5, SAB
Domain Architecture
Description	SH3 domain-binding protein 5 (SH3 domain-binding protein that preferentially associates with BTK).

3BP5_MOUSE
θ value	θ > 10 (rank : 257)	NC score	0.064946 (rank : 681)
Query Neighborhood Hits	255	Target Neighborhood Hits	346	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Z131, Q8C903, Q8VCZ0	Gene names	Sh3bp5, Sab
Domain Architecture
Description	SH3 domain-binding protein 5 (SH3 domain-binding protein that preferentially associates with BTK).

ABI1_HUMAN
θ value	θ > 10 (rank : 258)	NC score	0.103685 (rank : 330)
Query Neighborhood Hits	255	Target Neighborhood Hits	257	Shared Neighborhood Hits	45
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

ABI1_MOUSE
θ value	θ > 10 (rank : 259)	NC score	0.112637 (rank : 272)
Query Neighborhood Hits	255	Target Neighborhood Hits	246	Shared Neighborhood Hits	47
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

ABI2_HUMAN
θ value	θ > 10 (rank : 260)	NC score	0.117119 (rank : 244)
Query Neighborhood Hits	255	Target Neighborhood Hits	350	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

ABI2_MOUSE
θ value	θ > 10 (rank : 261)	NC score	0.116809 (rank : 247)
Query Neighborhood Hits	255	Target Neighborhood Hits	266	Shared Neighborhood Hits	47
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

ABI3_HUMAN
θ value	θ > 10 (rank : 262)	NC score	0.095832 (rank : 398)
Query Neighborhood Hits	255	Target Neighborhood Hits	227	Shared Neighborhood Hits	37
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ABI3_MOUSE
θ value	θ > 10 (rank : 263)	NC score	0.095621 (rank : 401)
Query Neighborhood Hits	255	Target Neighborhood Hits	227	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ADIP_HUMAN
θ value	θ > 10 (rank : 264)	NC score	0.075645 (rank : 587)
Query Neighborhood Hits	255	Target Neighborhood Hits	470	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y2D8, Q6P2P8, Q6ULS1, Q7L168, Q9UIX0	Gene names	SSX2IP, KIAA0923
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein) (SSX2-interacting protein).

ADIP_MOUSE
θ value	θ > 10 (rank : 265)	NC score	0.060204 (rank : 742)
Query Neighborhood Hits	255	Target Neighborhood Hits	415	Shared Neighborhood Hits	68
SwissProt Accessions	Q8VC66, Q8BG59, Q8C7X0, Q8K2F7	Gene names	Ssx2ip
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein).

AHI1_HUMAN
θ value	θ > 10 (rank : 266)	NC score	0.105217 (rank : 323)
Query Neighborhood Hits	255	Target Neighborhood Hits	537	Shared Neighborhood Hits	54
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

AHI1_MOUSE
θ value	θ > 10 (rank : 267)	NC score	0.100813 (rank : 349)
Query Neighborhood Hits	255	Target Neighborhood Hits	496	Shared Neighborhood Hits	52
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

AKAP6_HUMAN
θ value	θ > 10 (rank : 268)	NC score	0.087761 (rank : 481)
Query Neighborhood Hits	255	Target Neighborhood Hits	263	Shared Neighborhood Hits	56
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

AKAP9_HUMAN
θ value	θ > 10 (rank : 269)	NC score	0.133419 (rank : 166)
Query Neighborhood Hits	255	Target Neighborhood Hits	1710	Shared Neighborhood Hits	141
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

AL2SB_HUMAN
θ value	θ > 10 (rank : 270)	NC score	0.072746 (rank : 616)
Query Neighborhood Hits	255	Target Neighborhood Hits	294	Shared Neighborhood Hits	66
SwissProt Accessions	Q96Q35	Gene names	ALS2CR12
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein.

AMOL1_HUMAN
θ value	θ > 10 (rank : 271)	NC score	0.065570 (rank : 674)
Query Neighborhood Hits	255	Target Neighborhood Hits	435	Shared Neighborhood Hits	81
SwissProt Accessions	Q8IY63, Q63HK7, Q8NDN0, Q8WXD1, Q96CM5	Gene names	AMOTL1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

AMOL1_MOUSE
θ value	θ > 10 (rank : 272)	NC score	0.062796 (rank : 717)
Query Neighborhood Hits	255	Target Neighborhood Hits	445	Shared Neighborhood Hits	79
SwissProt Accessions	Q9D4H4, Q571F1	Gene names	Amotl1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

AMOL2_HUMAN
θ value	θ > 10 (rank : 273)	NC score	0.076706 (rank : 577)
Query Neighborhood Hits	255	Target Neighborhood Hits	603	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Y2J4, Q53EP1, Q96F99, Q9UKB4	Gene names	AMOTL2, KIAA0989
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP).

AMOL2_MOUSE
θ value	θ > 10 (rank : 274)	NC score	0.073278 (rank : 611)
Query Neighborhood Hits	255	Target Neighborhood Hits	591	Shared Neighborhood Hits	95
SwissProt Accessions	Q8K371, Q3TPM1, Q7TPE4, Q8BP84, Q8BS08, Q9QUS0	Gene names	Amotl2
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2.

AMOT_HUMAN
θ value	θ > 10 (rank : 275)	NC score	0.060863 (rank : 735)
Query Neighborhood Hits	255	Target Neighborhood Hits	712	Shared Neighborhood Hits	80
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

AN30A_HUMAN
θ value	θ > 10 (rank : 276)	NC score	0.071870 (rank : 623)
Query Neighborhood Hits	255	Target Neighborhood Hits	1119	Shared Neighborhood Hits	109
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

ANM2_HUMAN
θ value	θ > 10 (rank : 277)	NC score	0.092505 (rank : 432)
Query Neighborhood Hits	255	Target Neighborhood Hits	175	Shared Neighborhood Hits	39
SwissProt Accessions	P55345, P78350, Q9BW15, Q9UMC2	Gene names	PRMT2, HMT1, HRMT1L1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

ANM2_MOUSE
θ value	θ > 10 (rank : 278)	NC score	0.086468 (rank : 496)
Query Neighborhood Hits	255	Target Neighborhood Hits	175	Shared Neighborhood Hits	38
SwissProt Accessions	Q9R144	Gene names	Prmt2, Hrmt1l1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

ANR18_HUMAN
θ value	θ > 10 (rank : 279)	NC score	0.058201 (rank : 767)
Query Neighborhood Hits	255	Target Neighborhood Hits	1106	Shared Neighborhood Hits	103
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

ANR26_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.093361 (rank : 425)
Query Neighborhood Hits	255	Target Neighborhood Hits	1614	Shared Neighborhood Hits	128
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ANR26_MOUSE
θ value	θ > 10 (rank : 281)	NC score	0.096082 (rank : 395)
Query Neighborhood Hits	255	Target Neighborhood Hits	1554	Shared Neighborhood Hits	134
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

APOA1_MOUSE
θ value	θ > 10 (rank : 282)	NC score	0.051374 (rank : 843)
Query Neighborhood Hits	255	Target Neighborhood Hits	210	Shared Neighborhood Hits	52
SwissProt Accessions	Q00623	Gene names	Apoa1
Domain Architecture
Description	Apolipoprotein A-I precursor (Apo-AI) (ApoA-I).

APOA4_HUMAN
θ value	θ > 10 (rank : 283)	NC score	0.073670 (rank : 608)
Query Neighborhood Hits	255	Target Neighborhood Hits	399	Shared Neighborhood Hits	78
SwissProt Accessions	P06727, Q6Q787	Gene names	APOA4
Domain Architecture
Description	Apolipoprotein A-IV precursor (Apo-AIV) (ApoA-IV).

APOA4_MOUSE
θ value	θ > 10 (rank : 284)	NC score	0.069934 (rank : 637)
Query Neighborhood Hits	255	Target Neighborhood Hits	435	Shared Neighborhood Hits	73
SwissProt Accessions	P06728	Gene names	Apoa4
Domain Architecture
Description	Apolipoprotein A-IV precursor (Apo-AIV) (ApoA-IV).

APOE_MOUSE
θ value	θ > 10 (rank : 285)	NC score	0.078077 (rank : 566)
Query Neighborhood Hits	255	Target Neighborhood Hits	319	Shared Neighborhood Hits	68
SwissProt Accessions	P08226	Gene names	Apoe
Domain Architecture
Description	Apolipoprotein E precursor (Apo-E).

ASPM_MOUSE
θ value	θ > 10 (rank : 286)	NC score	0.053885 (rank : 810)
Query Neighborhood Hits	255	Target Neighborhood Hits	150	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CJ27, O88482, Q8BJI8, Q8BKT4	Gene names	Aspm, Calmbp1, Sha1
Domain Architecture
Description	Abnormal spindle-like microcephaly-associated protein homolog (Calmodulin-binding protein 1) (Spindle and hydroxyurea checkpoint abnormal protein) (Calmodulin-binding protein Sha1).

ASPP1_HUMAN
θ value	θ > 10 (rank : 287)	NC score	0.096974 (rank : 388)
Query Neighborhood Hits	255	Target Neighborhood Hits	956	Shared Neighborhood Hits	109
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ASPP1_MOUSE
θ value	θ > 10 (rank : 288)	NC score	0.096980 (rank : 387)
Query Neighborhood Hits	255	Target Neighborhood Hits	1244	Shared Neighborhood Hits	118
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ASPP2_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.094964 (rank : 411)
Query Neighborhood Hits	255	Target Neighborhood Hits	1156	Shared Neighborhood Hits	124
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

AZI1_HUMAN
θ value	θ > 10 (rank : 290)	NC score	0.114235 (rank : 258)
Query Neighborhood Hits	255	Target Neighborhood Hits	1000	Shared Neighborhood Hits	118
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

AZI1_MOUSE
θ value	θ > 10 (rank : 291)	NC score	0.106417 (rank : 308)
Query Neighborhood Hits	255	Target Neighborhood Hits	990	Shared Neighborhood Hits	117
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

BAIP2_HUMAN
θ value	θ > 10 (rank : 292)	NC score	0.063584 (rank : 702)
Query Neighborhood Hits	255	Target Neighborhood Hits	192	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UQB8, O43858, Q53HB1, Q86WC1, Q8N5C0, Q96CR7, Q9UBR3, Q9UQ43	Gene names	BAIAP2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Protein BAP2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor substrate p53/p58) (IRSp53/58) (IRS-58) (Fas ligand-associated factor 3) (FLAF3).

BAIP2_MOUSE
θ value	θ > 10 (rank : 293)	NC score	0.063369 (rank : 706)
Query Neighborhood Hits	255	Target Neighborhood Hits	185	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BKX1, Q91V97, Q923V9, Q923W0	Gene names	Baiap2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor tyrosine kinase 53 kDa substrate).

BCN1_HUMAN
θ value	θ > 10 (rank : 294)	NC score	0.055445 (rank : 789)
Query Neighborhood Hits	255	Target Neighborhood Hits	395	Shared Neighborhood Hits	71
SwissProt Accessions	Q14457, O75595, Q9UNA8	Gene names	BECN1, GT197
Domain Architecture
Description	Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197).

BCN1_MOUSE
θ value	θ > 10 (rank : 295)	NC score	0.056461 (rank : 785)
Query Neighborhood Hits	255	Target Neighborhood Hits	367	Shared Neighborhood Hits	74
SwissProt Accessions	O88597	Gene names	Becn1
Domain Architecture
Description	Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein).

BFSP1_HUMAN
θ value	θ > 10 (rank : 296)	NC score	0.056465 (rank : 784)
Query Neighborhood Hits	255	Target Neighborhood Hits	508	Shared Neighborhood Hits	84
SwissProt Accessions	Q12934, O43595, O76034, Q9HBX4	Gene names	BFSP1
Domain Architecture
Description	Filensin (Beaded filament structural protein 1) (Lens fiber cell beaded-filament structural protein CP 115) (CP115) (Lens intermediate filament-like heavy) (LIFL-H).

BI2L1_HUMAN
θ value	θ > 10 (rank : 297)	NC score	0.092060 (rank : 438)
Query Neighborhood Hits	255	Target Neighborhood Hits	156	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UHR4, Q75L21, Q75L22, Q96CV4, Q9Y2M8	Gene names	BAIAP2L1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

BI2L1_MOUSE
θ value	θ > 10 (rank : 298)	NC score	0.071711 (rank : 624)
Query Neighborhood Hits	255	Target Neighborhood Hits	197	Shared Neighborhood Hits	36
SwissProt Accessions	Q9DBJ3	Gene names	Baiap2l1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

BICD1_HUMAN
θ value	θ > 10 (rank : 299)	NC score	0.098245 (rank : 369)
Query Neighborhood Hits	255	Target Neighborhood Hits	844	Shared Neighborhood Hits	102
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

BICD1_MOUSE
θ value	θ > 10 (rank : 300)	NC score	0.097723 (rank : 377)
Query Neighborhood Hits	255	Target Neighborhood Hits	837	Shared Neighborhood Hits	102
SwissProt Accessions	Q8BR07, O55206, Q8BQ18, Q8BRR8, Q8C4D3, Q8CAK6, Q8R2J4, Q8R2J5, Q8R2J6, Q91YP7	Gene names	Bicd1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

BICD2_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.088875 (rank : 467)
Query Neighborhood Hits	255	Target Neighborhood Hits	856	Shared Neighborhood Hits	104
SwissProt Accessions	Q8TD16, O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561	Gene names	BICD2, KIAA0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

BICD2_MOUSE
θ value	θ > 10 (rank : 302)	NC score	0.090649 (rank : 452)
Query Neighborhood Hits	255	Target Neighborhood Hits	864	Shared Neighborhood Hits	104
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

BIN3_MOUSE
θ value	θ > 10 (rank : 303)	NC score	0.055278 (rank : 791)
Query Neighborhood Hits	255	Target Neighborhood Hits	165	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JI08	Gene names	Bin3
Domain Architecture	No domain graphic available
Description	Bridging integrator 3.

BRAP_HUMAN
θ value	θ > 10 (rank : 304)	NC score	0.059544 (rank : 754)
Query Neighborhood Hits	255	Target Neighborhood Hits	560	Shared Neighborhood Hits	76
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

BRE1A_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.099949 (rank : 357)
Query Neighborhood Hits	255	Target Neighborhood Hits	1071	Shared Neighborhood Hits	117
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

BRE1A_MOUSE
θ value	θ > 10 (rank : 306)	NC score	0.101549 (rank : 345)
Query Neighborhood Hits	255	Target Neighborhood Hits	1025	Shared Neighborhood Hits	114
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

BRE1B_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.093613 (rank : 420)
Query Neighborhood Hits	255	Target Neighborhood Hits	1040	Shared Neighborhood Hits	103
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

BRE1B_MOUSE
θ value	θ > 10 (rank : 308)	NC score	0.086918 (rank : 491)
Query Neighborhood Hits	255	Target Neighborhood Hits	970	Shared Neighborhood Hits	103
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

C102B_HUMAN
θ value	θ > 10 (rank : 309)	NC score	0.095826 (rank : 399)
Query Neighborhood Hits	255	Target Neighborhood Hits	542	Shared Neighborhood Hits	87
SwissProt Accessions	Q68D86, Q7Z467, Q8NDK7, Q9H5C1	Gene names	CCDC102B, C18orf14
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 102B.

CA065_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.083372 (rank : 532)
Query Neighborhood Hits	255	Target Neighborhood Hits	469	Shared Neighborhood Hits	77
SwissProt Accessions	Q8N715, Q8N746, Q8NA93	Gene names	C1orf65
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf65.

CAF1A_MOUSE
θ value	θ > 10 (rank : 311)	NC score	0.081753 (rank : 541)
Query Neighborhood Hits	255	Target Neighborhood Hits	736	Shared Neighborhood Hits	92
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CALD1_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.098303 (rank : 368)
Query Neighborhood Hits	255	Target Neighborhood Hits	959	Shared Neighborhood Hits	105
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

CAR10_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.068939 (rank : 649)
Query Neighborhood Hits	255	Target Neighborhood Hits	569	Shared Neighborhood Hits	88
SwissProt Accessions	Q9BWT7, Q14CQ8, Q5TFG6, Q9UGR5, Q9UGR6, Q9Y3H0	Gene names	CARD10, CARMA3
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3).

CAR10_MOUSE
θ value	θ > 10 (rank : 314)	NC score	0.058560 (rank : 763)
Query Neighborhood Hits	255	Target Neighborhood Hits	407	Shared Neighborhood Hits	83
SwissProt Accessions	P58660	Gene names	Card10, Bimp1
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (Bcl10-interacting MAGUK protein 1) (Bimp1).

CAR11_HUMAN
θ value	θ > 10 (rank : 315)	NC score	0.080955 (rank : 546)
Query Neighborhood Hits	255	Target Neighborhood Hits	690	Shared Neighborhood Hits	96
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

CAR14_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.059844 (rank : 750)
Query Neighborhood Hits	255	Target Neighborhood Hits	449	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BXL6, Q9BVB5	Gene names	CARD14, CARMA2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (CARD-containing MAGUK protein 2) (Carma 2).

CAR14_MOUSE
θ value	θ > 10 (rank : 317)	NC score	0.060999 (rank : 734)
Query Neighborhood Hits	255	Target Neighborhood Hits	526	Shared Neighborhood Hits	77
SwissProt Accessions	Q99KF0	Gene names	Card14, Bimp2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (Bcl10-interacting MAGUK protein 2) (Bimp2).

CARD9_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.095320 (rank : 407)
Query Neighborhood Hits	255	Target Neighborhood Hits	602	Shared Neighborhood Hits	93
SwissProt Accessions	Q9H257, Q5SXM6, Q9H854	Gene names	CARD9
Domain Architecture
Description	Caspase recruitment domain-containing protein 9 (hCARD9).

CASP_HUMAN
θ value	θ > 10 (rank : 319)	NC score	0.107382 (rank : 302)
Query Neighborhood Hits	255	Target Neighborhood Hits	1131	Shared Neighborhood Hits	119
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CASP_MOUSE
θ value	θ > 10 (rank : 320)	NC score	0.107075 (rank : 306)
Query Neighborhood Hits	255	Target Neighborhood Hits	1152	Shared Neighborhood Hits	120
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CCD11_HUMAN
θ value	θ > 10 (rank : 321)	NC score	0.097188 (rank : 381)
Query Neighborhood Hits	255	Target Neighborhood Hits	822	Shared Neighborhood Hits	110
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CCD11_MOUSE
θ value	θ > 10 (rank : 322)	NC score	0.091671 (rank : 443)
Query Neighborhood Hits	255	Target Neighborhood Hits	498	Shared Neighborhood Hits	89
SwissProt Accessions	Q9D439	Gene names	Ccdc11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CCD13_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.111125 (rank : 283)
Query Neighborhood Hits	255	Target Neighborhood Hits	721	Shared Neighborhood Hits	100
SwissProt Accessions	Q8IYE1	Gene names	CCDC13
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 13.

CCD19_HUMAN
θ value	θ > 10 (rank : 324)	NC score	0.103143 (rank : 334)
Query Neighborhood Hits	255	Target Neighborhood Hits	639	Shared Neighborhood Hits	101
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

CCD21_HUMAN
θ value	θ > 10 (rank : 325)	NC score	0.111171 (rank : 281)
Query Neighborhood Hits	255	Target Neighborhood Hits	1228	Shared Neighborhood Hits	127
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CCD22_HUMAN
θ value	θ > 10 (rank : 326)	NC score	0.055000 (rank : 796)
Query Neighborhood Hits	255	Target Neighborhood Hits	242	Shared Neighborhood Hits	58
SwissProt Accessions	O60826	Gene names	CCDC22, CXorf37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 22.

CCD22_MOUSE
θ value	θ > 10 (rank : 327)	NC score	0.059550 (rank : 753)
Query Neighborhood Hits	255	Target Neighborhood Hits	268	Shared Neighborhood Hits	57
SwissProt Accessions	Q9JIG7, Q8BYH4	Gene names	Ccdc22, DXImx40e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 22.

CCD27_HUMAN
θ value	θ > 10 (rank : 328)	NC score	0.096462 (rank : 391)
Query Neighborhood Hits	255	Target Neighborhood Hits	594	Shared Neighborhood Hits	98
SwissProt Accessions	Q2M243, Q5TBV3, Q96M50	Gene names	CCDC27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

CCD27_MOUSE
θ value	θ > 10 (rank : 329)	NC score	0.092090 (rank : 436)
Query Neighborhood Hits	255	Target Neighborhood Hits	461	Shared Neighborhood Hits	86
SwissProt Accessions	Q3V036	Gene names	Ccdc27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

CCD39_HUMAN
θ value	θ > 10 (rank : 330)	NC score	0.113162 (rank : 264)
Query Neighborhood Hits	255	Target Neighborhood Hits	868	Shared Neighborhood Hits	106
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CCD39_MOUSE
θ value	θ > 10 (rank : 331)	NC score	0.118082 (rank : 239)
Query Neighborhood Hits	255	Target Neighborhood Hits	1026	Shared Neighborhood Hits	109
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CCD41_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.111797 (rank : 277)
Query Neighborhood Hits	255	Target Neighborhood Hits	1139	Shared Neighborhood Hits	123
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

CCD41_MOUSE
θ value	θ > 10 (rank : 333)	NC score	0.116123 (rank : 248)
Query Neighborhood Hits	255	Target Neighborhood Hits	1399	Shared Neighborhood Hits	121
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

CCD42_HUMAN
θ value	θ > 10 (rank : 334)	NC score	0.073830 (rank : 604)
Query Neighborhood Hits	255	Target Neighborhood Hits	406	Shared Neighborhood Hits	82
SwissProt Accessions	Q96M95, Q8N6Q0	Gene names	CCDC42
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 42.

CCD42_MOUSE
θ value	θ > 10 (rank : 335)	NC score	0.072734 (rank : 617)
Query Neighborhood Hits	255	Target Neighborhood Hits	284	Shared Neighborhood Hits	77
SwissProt Accessions	Q5SV66, Q8BNY1	Gene names	Ccdc42
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 42.

CCD45_HUMAN
θ value	θ > 10 (rank : 336)	NC score	0.063758 (rank : 699)
Query Neighborhood Hits	255	Target Neighborhood Hits	525	Shared Neighborhood Hits	77
SwissProt Accessions	Q96GE4, Q96M81	Gene names	CCDC45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

CCD45_MOUSE
θ value	θ > 10 (rank : 337)	NC score	0.072153 (rank : 622)
Query Neighborhood Hits	255	Target Neighborhood Hits	663	Shared Neighborhood Hits	85
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

CCD46_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.122392 (rank : 213)
Query Neighborhood Hits	255	Target Neighborhood Hits	1430	Shared Neighborhood Hits	126
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

CCD46_MOUSE
θ value	θ > 10 (rank : 339)	NC score	0.116070 (rank : 249)
Query Neighborhood Hits	255	Target Neighborhood Hits	1405	Shared Neighborhood Hits	127
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

CCD62_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.106207 (rank : 311)
Query Neighborhood Hits	255	Target Neighborhood Hits	631	Shared Neighborhood Hits	98
SwissProt Accessions	Q6P9F0, Q6ZVF2, Q86VJ0, Q9BYZ5	Gene names	CCDC62
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60 (Aaa-protein) (Protein TSP- NY).

CCD91_HUMAN
θ value	θ > 10 (rank : 341)	NC score	0.105299 (rank : 320)
Query Neighborhood Hits	255	Target Neighborhood Hits	868	Shared Neighborhood Hits	105
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

CCD93_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.085931 (rank : 503)
Query Neighborhood Hits	255	Target Neighborhood Hits	600	Shared Neighborhood Hits	91
SwissProt Accessions	Q567U6, Q4LE78, Q53TJ2, Q8TBX5, Q9H6R5, Q9NV15	Gene names	CCDC93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

CCD93_MOUSE
θ value	θ > 10 (rank : 343)	NC score	0.071323 (rank : 626)
Query Neighborhood Hits	255	Target Neighborhood Hits	362	Shared Neighborhood Hits	74
SwissProt Accessions	Q7TQK5, Q3TX53	Gene names	Ccdc93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

CCD96_HUMAN
θ value	θ > 10 (rank : 344)	NC score	0.093172 (rank : 427)
Query Neighborhood Hits	255	Target Neighborhood Hits	595	Shared Neighborhood Hits	87
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CCD96_MOUSE
θ value	θ > 10 (rank : 345)	NC score	0.100463 (rank : 354)
Query Neighborhood Hits	255	Target Neighborhood Hits	704	Shared Neighborhood Hits	96
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CCDC6_HUMAN
θ value	θ > 10 (rank : 346)	NC score	0.088707 (rank : 471)
Query Neighborhood Hits	255	Target Neighborhood Hits	723	Shared Neighborhood Hits	96
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

CCDC7_HUMAN
θ value	θ > 10 (rank : 347)	NC score	0.064146 (rank : 691)
Query Neighborhood Hits	255	Target Neighborhood Hits	253	Shared Neighborhood Hits	56
SwissProt Accessions	Q96M83, Q8IVQ0, Q8NEQ0	Gene names	CCDC7
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 7.

CCHCR_HUMAN
θ value	θ > 10 (rank : 348)	NC score	0.110739 (rank : 286)
Query Neighborhood Hits	255	Target Neighborhood Hits	717	Shared Neighborhood Hits	104
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

CCHCR_MOUSE
θ value	θ > 10 (rank : 349)	NC score	0.104018 (rank : 329)
Query Neighborhood Hits	255	Target Neighborhood Hits	932	Shared Neighborhood Hits	107
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

CD2AP_HUMAN
θ value	θ > 10 (rank : 350)	NC score	0.169837 (rank : 113)
Query Neighborhood Hits	255	Target Neighborhood Hits	315	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

CD2AP_MOUSE
θ value	θ > 10 (rank : 351)	NC score	0.170163 (rank : 112)
Query Neighborhood Hits	255	Target Neighborhood Hits	336	Shared Neighborhood Hits	58
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

CDC37_HUMAN
θ value	θ > 10 (rank : 352)	NC score	0.057886 (rank : 772)
Query Neighborhood Hits	255	Target Neighborhood Hits	506	Shared Neighborhood Hits	67
SwissProt Accessions	Q16543	Gene names	CDC37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

CDC37_MOUSE
θ value	θ > 10 (rank : 353)	NC score	0.055353 (rank : 790)
Query Neighborhood Hits	255	Target Neighborhood Hits	359	Shared Neighborhood Hits	70
SwissProt Accessions	Q61081, Q3TGP0	Gene names	Cdc37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

CDR2_HUMAN
θ value	θ > 10 (rank : 354)	NC score	0.089698 (rank : 462)
Query Neighborhood Hits	255	Target Neighborhood Hits	404	Shared Neighborhood Hits	87
SwissProt Accessions	Q01850, Q13977	Gene names	CDR2, PCD17
Domain Architecture	No domain graphic available
Description	Cerebellar degeneration-related protein 2 (Paraneoplastic cerebellar degeneration-associated antigen) (Major Yo paraneoplastic antigen).

CDR2_MOUSE
θ value	θ > 10 (rank : 355)	NC score	0.092941 (rank : 429)
Query Neighborhood Hits	255	Target Neighborhood Hits	482	Shared Neighborhood Hits	89
SwissProt Accessions	P97817	Gene names	Cdr2
Domain Architecture	No domain graphic available
Description	Cerebellar degeneration-related protein 2.

CE152_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.125930 (rank : 197)
Query Neighborhood Hits	255	Target Neighborhood Hits	976	Shared Neighborhood Hits	111
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

CE290_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.129024 (rank : 183)
Query Neighborhood Hits	255	Target Neighborhood Hits	1553	Shared Neighborhood Hits	134
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CENPH_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.073267 (rank : 612)
Query Neighborhood Hits	255	Target Neighborhood Hits	335	Shared Neighborhood Hits	71
SwissProt Accessions	Q9H3R5	Gene names	CENPH, ICEN35
Domain Architecture	No domain graphic available
Description	Centromere protein H (CENP-H) (Interphase centromere complex protein 35).

CENPH_MOUSE
θ value	θ > 10 (rank : 359)	NC score	0.058814 (rank : 760)
Query Neighborhood Hits	255	Target Neighborhood Hits	195	Shared Neighborhood Hits	53
SwissProt Accessions	Q9QYM8, Q8R3K9, Q9D079, Q9D0N1	Gene names	Cenph, Enp
Domain Architecture	No domain graphic available
Description	Centromere protein H (CENP-H).

CENPJ_HUMAN
θ value	θ > 10 (rank : 360)	NC score	0.075636 (rank : 588)
Query Neighborhood Hits	255	Target Neighborhood Hits	721	Shared Neighborhood Hits	92
SwissProt Accessions	Q9HC77, Q5T6R5, Q96KS5, Q9C067	Gene names	CENPJ, CPAP, LAP, LIP1
Domain Architecture	No domain graphic available
Description	Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1).

CENPK_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.070160 (rank : 636)
Query Neighborhood Hits	255	Target Neighborhood Hits	273	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BS16, Q9H4L0	Gene names	CENPK, ICEN37
Domain Architecture	No domain graphic available
Description	Centromere protein K (CENP-K) (Interphase centromere complex protein 37) (Protein AF-5alpha) (p33).

CENPU_HUMAN
θ value	θ > 10 (rank : 362)	NC score	0.050503 (rank : 854)
Query Neighborhood Hits	255	Target Neighborhood Hits	289	Shared Neighborhood Hits	61
SwissProt Accessions	Q71F23, Q32Q71, Q9H5G1	Gene names	MLF1IP, CENPU, ICEN24, KLIP1
Domain Architecture	No domain graphic available
Description	Centromere protein U (CENP-U) (CENP-U(50)) (CENP-50) (Interphase centromere complex protein 24) (MLF1-interacting protein) (KSHV latent nuclear antigen-interacting protein 1).

CEP35_HUMAN
θ value	θ > 10 (rank : 363)	NC score	0.065239 (rank : 678)
Query Neighborhood Hits	255	Target Neighborhood Hits	811	Shared Neighborhood Hits	81
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

CEP55_HUMAN
θ value	θ > 10 (rank : 364)	NC score	0.092089 (rank : 437)
Query Neighborhood Hits	255	Target Neighborhood Hits	504	Shared Neighborhood Hits	86
SwissProt Accessions	Q53EZ4, Q32WF5, Q3MV20, Q5VY28, Q6N034, Q96H32, Q9NVS7	Gene names	CEP55, C10orf3, URCC6
Domain Architecture	No domain graphic available
Description	Centrosome protein 55 (Up-regulated in colon cancer 6).

CEP55_MOUSE
θ value	θ > 10 (rank : 365)	NC score	0.095497 (rank : 404)
Query Neighborhood Hits	255	Target Neighborhood Hits	693	Shared Neighborhood Hits	96
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

CEP57_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.077135 (rank : 574)
Query Neighborhood Hits	255	Target Neighborhood Hits	576	Shared Neighborhood Hits	93
SwissProt Accessions	Q86XR8, Q14704, Q8IXP0, Q9BVF9	Gene names	CEP57, KIAA0092, TSP57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin) (FGF2-interacting protein).

CEP57_MOUSE
θ value	θ > 10 (rank : 367)	NC score	0.069554 (rank : 640)
Query Neighborhood Hits	255	Target Neighborhood Hits	580	Shared Neighborhood Hits	88
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

CEP63_HUMAN
θ value	θ > 10 (rank : 368)	NC score	0.131328 (rank : 170)
Query Neighborhood Hits	255	Target Neighborhood Hits	1005	Shared Neighborhood Hits	120
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

CEP70_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.079180 (rank : 558)
Query Neighborhood Hits	255	Target Neighborhood Hits	432	Shared Neighborhood Hits	79
SwissProt Accessions	Q8NHQ1, Q96B31, Q9H2C3, Q9H2Z1, Q9H940	Gene names	CEP70, BITE
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 70 kDa (Cep70 protein) (p10-binding protein).

CEP70_MOUSE
θ value	θ > 10 (rank : 370)	NC score	0.075960 (rank : 584)
Query Neighborhood Hits	255	Target Neighborhood Hits	532	Shared Neighborhood Hits	82
SwissProt Accessions	Q6IQY5, Q9CRL9, Q9CTS4, Q9JIC1	Gene names	Cep70
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 70 kDa (Cep70 protein).

CEP72_MOUSE
θ value	θ > 10 (rank : 371)	NC score	0.054541 (rank : 803)
Query Neighborhood Hits	255	Target Neighborhood Hits	381	Shared Neighborhood Hits	59
SwissProt Accessions	Q9D3R3, Q8BM53, Q9D0B7	Gene names	Cep72
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 72 kDa (Cep72 protein).

CF060_HUMAN
θ value	θ > 10 (rank : 372)	NC score	0.129572 (rank : 178)
Query Neighborhood Hits	255	Target Neighborhood Hits	1270	Shared Neighborhood Hits	128
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

CF152_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.078578 (rank : 561)
Query Neighborhood Hits	255	Target Neighborhood Hits	704	Shared Neighborhood Hits	95
SwissProt Accessions	Q86VQ0, Q9BWX7	Gene names	C6orf152
Domain Architecture	No domain graphic available
Description	Protein C6orf152.

CF152_MOUSE
θ value	θ > 10 (rank : 374)	NC score	0.068705 (rank : 651)
Query Neighborhood Hits	255	Target Neighborhood Hits	597	Shared Neighborhood Hits	84
SwissProt Accessions	Q80ST9, Q9CYM9, Q9D5J9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf152 homolog.

CF182_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.074847 (rank : 597)
Query Neighborhood Hits	255	Target Neighborhood Hits	474	Shared Neighborhood Hits	80
SwissProt Accessions	Q8IYX8	Gene names	C6orf182
Domain Architecture	No domain graphic available
Description	Protein C6orf182.

CF182_MOUSE
θ value	θ > 10 (rank : 376)	NC score	0.086535 (rank : 494)
Query Neighborhood Hits	255	Target Neighborhood Hits	551	Shared Neighborhood Hits	87
SwissProt Accessions	Q8VDS7, Q9CZE0, Q9D5A1	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf182 homolog.

CI039_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.118224 (rank : 238)
Query Neighborhood Hits	255	Target Neighborhood Hits	1171	Shared Neighborhood Hits	120
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

CI093_HUMAN
θ value	θ > 10 (rank : 378)	NC score	0.118522 (rank : 235)
Query Neighborhood Hits	255	Target Neighborhood Hits	1088	Shared Neighborhood Hits	123
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

CING_HUMAN
θ value	θ > 10 (rank : 379)	NC score	0.118977 (rank : 232)
Query Neighborhood Hits	255	Target Neighborhood Hits	1275	Shared Neighborhood Hits	123
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

CING_MOUSE
θ value	θ > 10 (rank : 380)	NC score	0.119204 (rank : 229)
Query Neighborhood Hits	255	Target Neighborhood Hits	1432	Shared Neighborhood Hits	131
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

CIP4_HUMAN
θ value	θ > 10 (rank : 381)	NC score	0.064963 (rank : 680)
Query Neighborhood Hits	255	Target Neighborhood Hits	374	Shared Neighborhood Hits	75
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

CJ068_HUMAN
θ value	θ > 10 (rank : 382)	NC score	0.052812 (rank : 823)
Query Neighborhood Hits	255	Target Neighborhood Hits	316	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H943, Q8N7T7	Gene names	C10orf68
Domain Architecture	No domain graphic available
Description	Protein C10orf68.

CKAP4_HUMAN
θ value	θ > 10 (rank : 383)	NC score	0.097127 (rank : 382)
Query Neighborhood Hits	255	Target Neighborhood Hits	592	Shared Neighborhood Hits	93
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

CKAP4_MOUSE
θ value	θ > 10 (rank : 384)	NC score	0.097274 (rank : 379)
Query Neighborhood Hits	255	Target Neighborhood Hits	596	Shared Neighborhood Hits	98
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

CLC4F_HUMAN
θ value	θ > 10 (rank : 385)	NC score	0.080085 (rank : 552)
Query Neighborhood Hits	255	Target Neighborhood Hits	513	Shared Neighborhood Hits	83
SwissProt Accessions	Q8N1N0	Gene names	CLEC4F, CLECSF13
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member F (C-type lectin superfamily member 13) (C-type lectin 13).

CLC4F_MOUSE
θ value	θ > 10 (rank : 386)	NC score	0.059943 (rank : 748)
Query Neighborhood Hits	255	Target Neighborhood Hits	572	Shared Neighborhood Hits	82
SwissProt Accessions	P70194, Q8BLZ8	Gene names	Clec4f, Clecsf13, Kclr
Domain Architecture
Description	C-type lectin domain family 4 member F (C-type lectin superfamily member 13) (C-type lectin 13) (Kupffer cell receptor).

CLMN_HUMAN
θ value	θ > 10 (rank : 387)	NC score	0.112968 (rank : 266)
Query Neighborhood Hits	255	Target Neighborhood Hits	205	Shared Neighborhood Hits	26
SwissProt Accessions	Q96JQ2, Q9H713, Q9HA23, Q9HA57, Q9UFP4, Q9ULN2	Gene names	CLMN, KIAA1188
Domain Architecture
Description	Calmin.

CLMN_MOUSE
θ value	θ > 10 (rank : 388)	NC score	0.110307 (rank : 288)
Query Neighborhood Hits	255	Target Neighborhood Hits	180	Shared Neighborhood Hits	24
SwissProt Accessions	Q8C5W0, Q91V71, Q91XT7, Q91XT8, Q91XU9	Gene names	Clmn
Domain Architecture
Description	Calmin.

CLUA1_MOUSE
θ value	θ > 10 (rank : 389)	NC score	0.052906 (rank : 820)
Query Neighborhood Hits	255	Target Neighborhood Hits	261	Shared Neighborhood Hits	60
SwissProt Accessions	Q8R3P7, Q6P3Y8	Gene names	Cluap1
Domain Architecture	No domain graphic available
Description	Clusterin-associated protein 1.

CN045_HUMAN
θ value	θ > 10 (rank : 390)	NC score	0.051663 (rank : 837)
Query Neighborhood Hits	255	Target Neighborhood Hits	227	Shared Neighborhood Hits	50
SwissProt Accessions	Q8ND07, Q9H5P8	Gene names	C14orf45
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf45.

CN145_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.117063 (rank : 245)
Query Neighborhood Hits	255	Target Neighborhood Hits	1196	Shared Neighborhood Hits	124
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

CNN1_HUMAN
θ value	θ > 10 (rank : 392)	NC score	0.053782 (rank : 811)
Query Neighborhood Hits	255	Target Neighborhood Hits	38	Shared Neighborhood Hits	11
SwissProt Accessions	P51911, O00638, Q15416, Q8IY93, Q99438	Gene names	CNN1
Domain Architecture
Description	Calponin-1 (Calponin H1, smooth muscle) (Basic calponin).

CNN1_MOUSE
θ value	θ > 10 (rank : 393)	NC score	0.053626 (rank : 812)
Query Neighborhood Hits	255	Target Neighborhood Hits	37	Shared Neighborhood Hits	10
SwissProt Accessions	Q08091	Gene names	Cnn1
Domain Architecture
Description	Calponin-1 (Calponin H1, smooth muscle) (Basic calponin).

CNN2_MOUSE
θ value	θ > 10 (rank : 394)	NC score	0.052925 (rank : 819)
Query Neighborhood Hits	255	Target Neighborhood Hits	39	Shared Neighborhood Hits	10
SwissProt Accessions	Q08093	Gene names	Cnn2
Domain Architecture
Description	Calponin-2 (Calponin H2, smooth muscle) (Neutral calponin).

CNN3_HUMAN
θ value	θ > 10 (rank : 395)	NC score	0.050737 (rank : 851)
Query Neighborhood Hits	255	Target Neighborhood Hits	43	Shared Neighborhood Hits	11
SwissProt Accessions	Q15417	Gene names	CNN3
Domain Architecture
Description	Calponin-3 (Calponin, acidic isoform).

CNN3_MOUSE
θ value	θ > 10 (rank : 396)	NC score	0.050687 (rank : 852)
Query Neighborhood Hits	255	Target Neighborhood Hits	45	Shared Neighborhood Hits	11
SwissProt Accessions	Q9DAW9, Q3TW23	Gene names	Cnn3
Domain Architecture	No domain graphic available
Description	Calponin-3 (Calponin, acidic isoform).

CNTRB_HUMAN
θ value	θ > 10 (rank : 397)	NC score	0.095792 (rank : 400)
Query Neighborhood Hits	255	Target Neighborhood Hits	690	Shared Neighborhood Hits	96
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CNTRB_MOUSE
θ value	θ > 10 (rank : 398)	NC score	0.103574 (rank : 332)
Query Neighborhood Hits	255	Target Neighborhood Hits	1029	Shared Neighborhood Hits	114
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

COVA1_HUMAN
θ value	θ > 10 (rank : 399)	NC score	0.067353 (rank : 664)
Query Neighborhood Hits	255	Target Neighborhood Hits	416	Shared Neighborhood Hits	76
SwissProt Accessions	Q16206, Q5VTJ1, Q5VTJ2, Q8WUX0, Q9NTP6, Q9UH82	Gene names	COVA1
Domain Architecture
Description	Tumor-associated hydroquinone oxidase (tNOX) (Cytosolic ovarian carcinoma antigen 1) (APK1 antigen) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)].

COVA1_MOUSE
θ value	θ > 10 (rank : 400)	NC score	0.072462 (rank : 619)
Query Neighborhood Hits	255	Target Neighborhood Hits	335	Shared Neighborhood Hits	60
SwissProt Accessions	Q8R0Z2, Q8BY59, Q8R372	Gene names	Cova1
Domain Architecture	No domain graphic available
Description	Tumor-associated hydroquinone oxidase (tNOX) (Cytosolic ovarian carcinoma antigen 1) (APK1 antigen) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)].

CP135_HUMAN
θ value	θ > 10 (rank : 401)	NC score	0.124705 (rank : 203)
Query Neighborhood Hits	255	Target Neighborhood Hits	1290	Shared Neighborhood Hits	130
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CR034_HUMAN
θ value	θ > 10 (rank : 402)	NC score	0.100976 (rank : 347)
Query Neighborhood Hits	255	Target Neighborhood Hits	538	Shared Neighborhood Hits	89
SwissProt Accessions	Q5BJE1, Q6ZP67, Q6ZU20	Gene names	C18orf34
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34.

CRCM_HUMAN
θ value	θ > 10 (rank : 403)	NC score	0.083234 (rank : 534)
Query Neighborhood Hits	255	Target Neighborhood Hits	520	Shared Neighborhood Hits	86
SwissProt Accessions	P23508	Gene names	MCC
Domain Architecture
Description	Colorectal mutant cancer protein (Protein MCC).

CRKL_HUMAN
θ value	θ > 10 (rank : 404)	NC score	0.129590 (rank : 177)
Query Neighborhood Hits	255	Target Neighborhood Hits	313	Shared Neighborhood Hits	45
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

CRKL_MOUSE
θ value	θ > 10 (rank : 405)	NC score	0.127118 (rank : 189)
Query Neighborhood Hits	255	Target Neighborhood Hits	307	Shared Neighborhood Hits	47
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

CRK_HUMAN
θ value	θ > 10 (rank : 406)	NC score	0.122131 (rank : 215)
Query Neighborhood Hits	255	Target Neighborhood Hits	308	Shared Neighborhood Hits	48
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CRK_MOUSE
θ value	θ > 10 (rank : 407)	NC score	0.126199 (rank : 195)
Query Neighborhood Hits	255	Target Neighborhood Hits	314	Shared Neighborhood Hits	49
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CT032_HUMAN
θ value	θ > 10 (rank : 408)	NC score	0.103134 (rank : 335)
Query Neighborhood Hits	255	Target Neighborhood Hits	235	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

CT096_HUMAN
θ value	θ > 10 (rank : 409)	NC score	0.085122 (rank : 510)
Query Neighborhood Hits	255	Target Neighborhood Hits	438	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NUD7, Q8N840, Q8NAX5	Gene names	C20orf96
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf96.

CT2NL_HUMAN
θ value	θ > 10 (rank : 410)	NC score	0.083820 (rank : 525)
Query Neighborhood Hits	255	Target Neighborhood Hits	1059	Shared Neighborhood Hits	104
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CT2NL_MOUSE
θ value	θ > 10 (rank : 411)	NC score	0.079148 (rank : 559)
Query Neighborhood Hits	255	Target Neighborhood Hits	902	Shared Neighborhood Hits	98
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CTGE2_HUMAN
θ value	θ > 10 (rank : 412)	NC score	0.073932 (rank : 601)
Query Neighborhood Hits	255	Target Neighborhood Hits	594	Shared Neighborhood Hits	93
SwissProt Accessions	Q96RT6	Gene names	CTAGE1, CTAGE2
Domain Architecture	No domain graphic available
Description	Protein cTAGE-2.

CTGE5_HUMAN
θ value	θ > 10 (rank : 413)	NC score	0.087698 (rank : 482)
Query Neighborhood Hits	255	Target Neighborhood Hits	800	Shared Neighborhood Hits	108
SwissProt Accessions	O15320, O00169, Q6P2R8, Q8IX92, Q8IX93	Gene names	CTAGE5, MEA11, MEA6, MGEA11, MGEA6
Domain Architecture
Description	Cutaneous T-cell lymphoma-associated antigen 5 (cTAGE-5 protein) (cTAGE family member 5) (Meningioma-expressed antigen 6/11).

CTGE5_MOUSE
θ value	θ > 10 (rank : 414)	NC score	0.091143 (rank : 447)
Query Neighborhood Hits	255	Target Neighborhood Hits	928	Shared Neighborhood Hits	106
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

CTGE6_HUMAN
θ value	θ > 10 (rank : 415)	NC score	0.073070 (rank : 614)
Query Neighborhood Hits	255	Target Neighborhood Hits	650	Shared Neighborhood Hits	90
SwissProt Accessions	Q86UF2	Gene names	CTAGE6
Domain Architecture	No domain graphic available
Description	Protein cTAGE-6 (cTAGE family member 6).

CTRO_HUMAN
θ value	θ > 10 (rank : 416)	NC score	0.077139 (rank : 573)
Query Neighborhood Hits	255	Target Neighborhood Hits	2092	Shared Neighborhood Hits	146
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

CTRO_MOUSE
θ value	θ > 10 (rank : 417)	NC score	0.082431 (rank : 540)
Query Neighborhood Hits	255	Target Neighborhood Hits	2344	Shared Neighborhood Hits	146
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

CU013_HUMAN
θ value	θ > 10 (rank : 418)	NC score	0.073434 (rank : 610)
Query Neighborhood Hits	255	Target Neighborhood Hits	405	Shared Neighborhood Hits	75
SwissProt Accessions	O95447	Gene names	C21orf13
Domain Architecture
Description	Protein C21orf13.

CUTL1_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.093422 (rank : 423)
Query Neighborhood Hits	255	Target Neighborhood Hits	1574	Shared Neighborhood Hits	126
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

CUTL1_MOUSE
θ value	θ > 10 (rank : 420)	NC score	0.089997 (rank : 459)
Query Neighborhood Hits	255	Target Neighborhood Hits	1620	Shared Neighborhood Hits	118
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

CYLN2_HUMAN
θ value	θ > 10 (rank : 421)	NC score	0.113583 (rank : 261)
Query Neighborhood Hits	255	Target Neighborhood Hits	1004	Shared Neighborhood Hits	116
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

CYLN2_MOUSE
θ value	θ > 10 (rank : 422)	NC score	0.110267 (rank : 289)
Query Neighborhood Hits	255	Target Neighborhood Hits	1002	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

CYTSA_HUMAN
θ value	θ > 10 (rank : 423)	NC score	0.149818 (rank : 139)
Query Neighborhood Hits	255	Target Neighborhood Hits	1138	Shared Neighborhood Hits	128
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

CYTSA_MOUSE
θ value	θ > 10 (rank : 424)	NC score	0.153209 (rank : 128)
Query Neighborhood Hits	255	Target Neighborhood Hits	1104	Shared Neighborhood Hits	127
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

DBNL_HUMAN
θ value	θ > 10 (rank : 425)	NC score	0.097255 (rank : 380)
Query Neighborhood Hits	255	Target Neighborhood Hits	244	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

DBNL_MOUSE
θ value	θ > 10 (rank : 426)	NC score	0.097025 (rank : 385)
Query Neighborhood Hits	255	Target Neighborhood Hits	306	Shared Neighborhood Hits	51
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

DDEF1_MOUSE
θ value	θ > 10 (rank : 427)	NC score	0.053398 (rank : 814)
Query Neighborhood Hits	255	Target Neighborhood Hits	592	Shared Neighborhood Hits	45
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

DDEF2_HUMAN
θ value	θ > 10 (rank : 428)	NC score	0.061083 (rank : 732)
Query Neighborhood Hits	255	Target Neighborhood Hits	599	Shared Neighborhood Hits	58
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
θ value	θ > 10 (rank : 429)	NC score	0.061084 (rank : 731)
Query Neighborhood Hits	255	Target Neighborhood Hits	625	Shared Neighborhood Hits	56
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DESP_HUMAN
θ value	θ > 10 (rank : 430)	NC score	0.137265 (rank : 162)
Query Neighborhood Hits	255	Target Neighborhood Hits	1470	Shared Neighborhood Hits	133
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

DLG5_HUMAN
θ value	θ > 10 (rank : 431)	NC score	0.083246 (rank : 533)
Query Neighborhood Hits	255	Target Neighborhood Hits	1088	Shared Neighborhood Hits	117
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

DMD_HUMAN
θ value	θ > 10 (rank : 432)	NC score	0.183707 (rank : 99)
Query Neighborhood Hits	255	Target Neighborhood Hits	1135	Shared Neighborhood Hits	125
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

DRP2_HUMAN
θ value	θ > 10 (rank : 433)	NC score	0.050841 (rank : 850)
Query Neighborhood Hits	255	Target Neighborhood Hits	186	Shared Neighborhood Hits	45
SwissProt Accessions	Q13474	Gene names	DRP2
Domain Architecture
Description	Dystrophin-related protein 2.

DYHC_HUMAN
θ value	θ > 10 (rank : 434)	NC score	0.062503 (rank : 719)
Query Neighborhood Hits	255	Target Neighborhood Hits	733	Shared Neighborhood Hits	102
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_MOUSE
θ value	θ > 10 (rank : 435)	NC score	0.062336 (rank : 720)
Query Neighborhood Hits	255	Target Neighborhood Hits	729	Shared Neighborhood Hits	104
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYNA_HUMAN
θ value	θ > 10 (rank : 436)	NC score	0.098712 (rank : 365)
Query Neighborhood Hits	255	Target Neighborhood Hits	1194	Shared Neighborhood Hits	124
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

DYNA_MOUSE
θ value	θ > 10 (rank : 437)	NC score	0.095619 (rank : 403)
Query Neighborhood Hits	255	Target Neighborhood Hits	1084	Shared Neighborhood Hits	118
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

DZIP1_MOUSE
θ value	θ > 10 (rank : 438)	NC score	0.060816 (rank : 736)
Query Neighborhood Hits	255	Target Neighborhood Hits	530	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BMD2, Q6ZQ10, Q9CRK5	Gene names	Dzip1, Kiaa0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1 homolog).

EFS_HUMAN
θ value	θ > 10 (rank : 439)	NC score	0.091038 (rank : 450)
Query Neighborhood Hits	255	Target Neighborhood Hits	348	Shared Neighborhood Hits	46
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

EFS_MOUSE
θ value	θ > 10 (rank : 440)	NC score	0.092050 (rank : 439)
Query Neighborhood Hits	255	Target Neighborhood Hits	389	Shared Neighborhood Hits	49
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

ENAH_HUMAN
θ value	θ > 10 (rank : 441)	NC score	0.067604 (rank : 659)
Query Neighborhood Hits	255	Target Neighborhood Hits	784	Shared Neighborhood Hits	90
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

EP15R_HUMAN
θ value	θ > 10 (rank : 442)	NC score	0.107236 (rank : 304)
Query Neighborhood Hits	255	Target Neighborhood Hits	1083	Shared Neighborhood Hits	117
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

EP15R_MOUSE
θ value	θ > 10 (rank : 443)	NC score	0.105217 (rank : 322)
Query Neighborhood Hits	255	Target Neighborhood Hits	1135	Shared Neighborhood Hits	115
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

EP15_HUMAN
θ value	θ > 10 (rank : 444)	NC score	0.102643 (rank : 338)
Query Neighborhood Hits	255	Target Neighborhood Hits	1021	Shared Neighborhood Hits	116
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

EP15_MOUSE
θ value	θ > 10 (rank : 445)	NC score	0.106280 (rank : 309)
Query Neighborhood Hits	255	Target Neighborhood Hits	820	Shared Neighborhood Hits	108
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

EPS8_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.052816 (rank : 822)
Query Neighborhood Hits	255	Target Neighborhood Hits	151	Shared Neighborhood Hits	35
SwissProt Accessions	Q12929, Q8N6J0	Gene names	EPS8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

EPS8_MOUSE
θ value	θ > 10 (rank : 447)	NC score	0.054705 (rank : 800)
Query Neighborhood Hits	255	Target Neighborhood Hits	157	Shared Neighborhood Hits	36
SwissProt Accessions	Q08509	Gene names	Eps8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

ERC2_HUMAN
θ value	θ > 10 (rank : 448)	NC score	0.119023 (rank : 231)
Query Neighborhood Hits	255	Target Neighborhood Hits	1156	Shared Neighborhood Hits	117
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

ERC2_MOUSE
θ value	θ > 10 (rank : 449)	NC score	0.120780 (rank : 223)
Query Neighborhood Hits	255	Target Neighborhood Hits	1166	Shared Neighborhood Hits	118
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

ES8L2_HUMAN
θ value	θ > 10 (rank : 450)	NC score	0.060545 (rank : 739)
Query Neighborhood Hits	255	Target Neighborhood Hits	193	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H6S3, Q53GM8, Q8WYW7, Q96K06, Q9H6K9	Gene names	EPS8L2, EPS8R2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

ES8L2_MOUSE
θ value	θ > 10 (rank : 451)	NC score	0.059023 (rank : 758)
Query Neighborhood Hits	255	Target Neighborhood Hits	169	Shared Neighborhood Hits	38
SwissProt Accessions	Q99K30, Q91VT7	Gene names	Eps8l2, Eps8r2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

ES8L3_HUMAN
θ value	θ > 10 (rank : 452)	NC score	0.061894 (rank : 727)
Query Neighborhood Hits	255	Target Neighborhood Hits	206	Shared Neighborhood Hits	34
SwissProt Accessions	Q8TE67, Q5T8Q6, Q5T8Q7, Q5T8Q8, Q96E47, Q9H719	Gene names	EPS8L3, EPS8R3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

ES8L3_MOUSE
θ value	θ > 10 (rank : 453)	NC score	0.058797 (rank : 761)
Query Neighborhood Hits	255	Target Neighborhood Hits	168	Shared Neighborhood Hits	39
SwissProt Accessions	Q91WL0, Q3TJ14	Gene names	Eps8l3, Eps8r3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor pathway substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

EZRI_HUMAN
θ value	θ > 10 (rank : 454)	NC score	0.060649 (rank : 737)
Query Neighborhood Hits	255	Target Neighborhood Hits	663	Shared Neighborhood Hits	96
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

EZRI_MOUSE
θ value	θ > 10 (rank : 455)	NC score	0.062113 (rank : 724)
Query Neighborhood Hits	255	Target Neighborhood Hits	693	Shared Neighborhood Hits	95
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

FA50A_HUMAN
θ value	θ > 10 (rank : 456)	NC score	0.051818 (rank : 835)
Query Neighborhood Hits	255	Target Neighborhood Hits	264	Shared Neighborhood Hits	60
SwissProt Accessions	Q14320, Q5HY37	Gene names	FAM50A, DXS9928E, HXC26, XAP5
Domain Architecture
Description	Protein FAM50A (Protein XAP-5) (Protein HXC-26).

FA50A_MOUSE
θ value	θ > 10 (rank : 457)	NC score	0.064002 (rank : 694)
Query Neighborhood Hits	255	Target Neighborhood Hits	293	Shared Neighborhood Hits	63
SwissProt Accessions	Q9WV03, Q9D866	Gene names	Fam50a, D0HXS9928E, Xap5
Domain Architecture
Description	Protein FAM50A (XAP-5 protein).

FARP1_HUMAN
θ value	θ > 10 (rank : 458)	NC score	0.306377 (rank : 73)
Query Neighborhood Hits	255	Target Neighborhood Hits	241	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

FLIP1_HUMAN
θ value	θ > 10 (rank : 459)	NC score	0.122518 (rank : 211)
Query Neighborhood Hits	255	Target Neighborhood Hits	1405	Shared Neighborhood Hits	133
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

FLIP1_MOUSE
θ value	θ > 10 (rank : 460)	NC score	0.114774 (rank : 256)
Query Neighborhood Hits	255	Target Neighborhood Hits	1176	Shared Neighborhood Hits	122
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

FLNA_HUMAN
θ value	θ > 10 (rank : 461)	NC score	0.084127 (rank : 521)
Query Neighborhood Hits	255	Target Neighborhood Hits	138	Shared Neighborhood Hits	28
SwissProt Accessions	P21333	Gene names	FLNA, FLN, FLN1
Domain Architecture
Description	Filamin-A (Alpha-filamin) (Filamin-1) (Endothelial actin-binding protein) (Actin-binding protein 280) (ABP-280) (Nonmuscle filamin).

FLNA_MOUSE
θ value	θ > 10 (rank : 462)	NC score	0.084258 (rank : 520)
Query Neighborhood Hits	255	Target Neighborhood Hits	142	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BTM8, O54934, Q7TQI1, Q8BLK1, Q8BTN7, Q8VHX5, Q8VHX8, Q99KQ2	Gene names	Flna, Fln, Fln1
Domain Architecture
Description	Filamin-A (Alpha-filamin) (Filamin-1) (Endothelial actin-binding protein) (Actin-binding protein 280) (ABP-280) (Nonmuscle filamin).

FLNB_HUMAN
θ value	θ > 10 (rank : 463)	NC score	0.084065 (rank : 523)
Query Neighborhood Hits	255	Target Neighborhood Hits	111	Shared Neighborhood Hits	28
SwissProt Accessions	O75369, Q13706, Q8WXS9, Q8WXT0, Q8WXT1, Q8WXT2, Q9NRB5, Q9NT26, Q9UEV9	Gene names	FLNB, FLN1L, FLN3, TABP, TAP
Domain Architecture
Description	Filamin-B (FLN-B) (Beta-filamin) (Actin-binding-like protein) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP) (ABP- 280 homolog) (ABP-278) (Filamin 3) (Filamin homolog 1) (Fh1).

FLNB_MOUSE
θ value	θ > 10 (rank : 464)	NC score	0.085060 (rank : 512)
Query Neighborhood Hits	255	Target Neighborhood Hits	126	Shared Neighborhood Hits	28
SwissProt Accessions	Q80X90, Q8VHX4, Q8VHX7, Q99KY3	Gene names	Flnb
Domain Architecture
Description	Filamin-B (FLN-B) (Beta-filamin) (Actin-binding-like protein) (ABP- 280-like protein).

FLNC_HUMAN
θ value	θ > 10 (rank : 465)	NC score	0.086154 (rank : 502)
Query Neighborhood Hits	255	Target Neighborhood Hits	116	Shared Neighborhood Hits	25
SwissProt Accessions	Q14315, O95303, Q07985, Q9NS12, Q9NYE5, Q9UMR8, Q9Y503	Gene names	FLNC, ABPL, FLN2
Domain Architecture
Description	Filamin-C (Gamma-filamin) (Filamin-2) (Protein FLNc) (Actin-binding- like protein) (ABP-L) (ABP-280-like protein).

FNBP2_HUMAN
θ value	θ > 10 (rank : 466)	NC score	0.079860 (rank : 556)
Query Neighborhood Hits	255	Target Neighborhood Hits	432	Shared Neighborhood Hits	76
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

FYCO1_HUMAN
θ value	θ > 10 (rank : 467)	NC score	0.148981 (rank : 141)
Query Neighborhood Hits	255	Target Neighborhood Hits	1149	Shared Neighborhood Hits	130
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

FYV1_HUMAN
θ value	θ > 10 (rank : 468)	NC score	0.067415 (rank : 661)
Query Neighborhood Hits	255	Target Neighborhood Hits	217	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

FYV1_MOUSE
θ value	θ > 10 (rank : 469)	NC score	0.063284 (rank : 708)
Query Neighborhood Hits	255	Target Neighborhood Hits	191	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

GAS8_HUMAN
θ value	θ > 10 (rank : 470)	NC score	0.104844 (rank : 326)
Query Neighborhood Hits	255	Target Neighborhood Hits	819	Shared Neighborhood Hits	108
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

GAS8_MOUSE
θ value	θ > 10 (rank : 471)	NC score	0.089056 (rank : 466)
Query Neighborhood Hits	255	Target Neighborhood Hits	622	Shared Neighborhood Hits	96
SwissProt Accessions	Q60779, Q99L71	Gene names	Gas8, Gas11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

GCC1_HUMAN
θ value	θ > 10 (rank : 472)	NC score	0.096475 (rank : 390)
Query Neighborhood Hits	255	Target Neighborhood Hits	887	Shared Neighborhood Hits	104
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

GCC1_MOUSE
θ value	θ > 10 (rank : 473)	NC score	0.090127 (rank : 457)
Query Neighborhood Hits	255	Target Neighborhood Hits	777	Shared Neighborhood Hits	100
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

GFAP_HUMAN
θ value	θ > 10 (rank : 474)	NC score	0.050633 (rank : 853)
Query Neighborhood Hits	255	Target Neighborhood Hits	723	Shared Neighborhood Hits	108
SwissProt Accessions	P14136, Q53H98, Q5D055, Q6ZQS3, Q7Z5J6, Q7Z5J7, Q96KS4, Q96P18, Q9UFD0	Gene names	GFAP
Domain Architecture
Description	Glial fibrillary acidic protein, astrocyte (GFAP).

GLE1_HUMAN
θ value	θ > 10 (rank : 475)	NC score	0.051006 (rank : 848)
Query Neighborhood Hits	255	Target Neighborhood Hits	445	Shared Neighborhood Hits	64
SwissProt Accessions	Q53GS7, O75458, Q53GT9, Q5VVU1, Q8NCP6, Q9UFL6	Gene names	GLE1L, GLE1
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein) (hGLE1).

GLE1_MOUSE
θ value	θ > 10 (rank : 476)	NC score	0.054140 (rank : 805)
Query Neighborhood Hits	255	Target Neighborhood Hits	504	Shared Neighborhood Hits	71
SwissProt Accessions	Q8R322, Q3TT10, Q3TU23, Q3UD65, Q8BT16, Q9D4A6	Gene names	Gle1l
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein).

GNRP_HUMAN
θ value	θ > 10 (rank : 477)	NC score	0.282582 (rank : 74)
Query Neighborhood Hits	255	Target Neighborhood Hits	239	Shared Neighborhood Hits	73
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

GNRP_MOUSE
θ value	θ > 10 (rank : 478)	NC score	0.313141 (rank : 71)
Query Neighborhood Hits	255	Target Neighborhood Hits	191	Shared Neighborhood Hits	72
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

GOG8A_HUMAN
θ value	θ > 10 (rank : 479)	NC score	0.090272 (rank : 455)
Query Neighborhood Hits	255	Target Neighborhood Hits	635	Shared Neighborhood Hits	98
SwissProt Accessions	Q9NZW0, O94937, Q9NZG8, Q9NZW3	Gene names	GOLGA8A, KIAA0855
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 8A/B (Golgi autoantigen golgin-67) (88 kDa Golgi protein) (Gm88 autoantigen).

GOGA1_MOUSE
θ value	θ > 10 (rank : 480)	NC score	0.120441 (rank : 224)
Query Neighborhood Hits	255	Target Neighborhood Hits	994	Shared Neighborhood Hits	119
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

GOGA2_HUMAN
θ value	θ > 10 (rank : 481)	NC score	0.112956 (rank : 267)
Query Neighborhood Hits	255	Target Neighborhood Hits	856	Shared Neighborhood Hits	108
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

GOGA2_MOUSE
θ value	θ > 10 (rank : 482)	NC score	0.117498 (rank : 242)
Query Neighborhood Hits	255	Target Neighborhood Hits	944	Shared Neighborhood Hits	116
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

GOGA3_HUMAN
θ value	θ > 10 (rank : 483)	NC score	0.136803 (rank : 163)
Query Neighborhood Hits	255	Target Neighborhood Hits	1317	Shared Neighborhood Hits	130
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

GOGA5_HUMAN
θ value	θ > 10 (rank : 484)	NC score	0.111222 (rank : 280)
Query Neighborhood Hits	255	Target Neighborhood Hits	1168	Shared Neighborhood Hits	122
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

GOGA5_MOUSE
θ value	θ > 10 (rank : 485)	NC score	0.110249 (rank : 290)
Query Neighborhood Hits	255	Target Neighborhood Hits	1434	Shared Neighborhood Hits	123
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

GOGA6_HUMAN
θ value	θ > 10 (rank : 486)	NC score	0.115953 (rank : 250)
Query Neighborhood Hits	255	Target Neighborhood Hits	1007	Shared Neighborhood Hits	113
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

GP73_HUMAN
θ value	θ > 10 (rank : 487)	NC score	0.063111 (rank : 713)
Query Neighborhood Hits	255	Target Neighborhood Hits	309	Shared Neighborhood Hits	61
SwissProt Accessions	Q8NBJ4, Q6IAF4, Q9NRB9	Gene names	GOLPH2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

GP73_MOUSE
θ value	θ > 10 (rank : 488)	NC score	0.070848 (rank : 630)
Query Neighborhood Hits	255	Target Neighborhood Hits	506	Shared Neighborhood Hits	71
SwissProt Accessions	Q91XA2	Gene names	Golph2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

GRAP1_HUMAN
θ value	θ > 10 (rank : 489)	NC score	0.125332 (rank : 201)
Query Neighborhood Hits	255	Target Neighborhood Hits	944	Shared Neighborhood Hits	119
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

GRAP1_MOUSE
θ value	θ > 10 (rank : 490)	NC score	0.120436 (rank : 225)
Query Neighborhood Hits	255	Target Neighborhood Hits	1234	Shared Neighborhood Hits	129
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

GRAP2_HUMAN
θ value	θ > 10 (rank : 491)	NC score	0.140218 (rank : 156)
Query Neighborhood Hits	255	Target Neighborhood Hits	304	Shared Neighborhood Hits	47
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

GRAP2_MOUSE
θ value	θ > 10 (rank : 492)	NC score	0.139702 (rank : 158)
Query Neighborhood Hits	255	Target Neighborhood Hits	297	Shared Neighborhood Hits	46
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

GRAP_HUMAN
θ value	θ > 10 (rank : 493)	NC score	0.159242 (rank : 117)
Query Neighborhood Hits	255	Target Neighborhood Hits	307	Shared Neighborhood Hits	50
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

GRAP_MOUSE
θ value	θ > 10 (rank : 494)	NC score	0.159511 (rank : 115)
Query Neighborhood Hits	255	Target Neighborhood Hits	309	Shared Neighborhood Hits	51
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

HAP1_HUMAN
θ value	θ > 10 (rank : 495)	NC score	0.078301 (rank : 564)
Query Neighborhood Hits	255	Target Neighborhood Hits	606	Shared Neighborhood Hits	96
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

HAP1_MOUSE
θ value	θ > 10 (rank : 496)	NC score	0.059135 (rank : 757)
Query Neighborhood Hits	255	Target Neighborhood Hits	388	Shared Neighborhood Hits	72
SwissProt Accessions	O35668, O35636	Gene names	Hap1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1).

HC127_HUMAN
θ value	θ > 10 (rank : 497)	NC score	0.068971 (rank : 647)
Query Neighborhood Hits	255	Target Neighborhood Hits	292	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NQZ6, Q5JTF9, Q9H9C3, Q9H9H7, Q9ULQ4	Gene names	HCA127, KIAA1166
Domain Architecture	No domain graphic available
Description	Hepatocellular carcinoma-associated antigen 127.

HC127_MOUSE
θ value	θ > 10 (rank : 498)	NC score	0.068971 (rank : 648)
Query Neighborhood Hits	255	Target Neighborhood Hits	292	Shared Neighborhood Hits	63
SwissProt Accessions	Q68FG0, Q6ZPW6	Gene names	Hca127, Kiaa1166
Domain Architecture	No domain graphic available
Description	Hepatocellular carcinoma-associated antigen 127 homolog.

HCLS1_HUMAN
θ value	θ > 10 (rank : 499)	NC score	0.124092 (rank : 206)
Query Neighborhood Hits	255	Target Neighborhood Hits	358	Shared Neighborhood Hits	45
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

HCLS1_MOUSE
θ value	θ > 10 (rank : 500)	NC score	0.127833 (rank : 186)
Query Neighborhood Hits	255	Target Neighborhood Hits	329	Shared Neighborhood Hits	47
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

HGS_HUMAN
θ value	θ > 10 (rank : 501)	NC score	0.084374 (rank : 518)
Query Neighborhood Hits	255	Target Neighborhood Hits	517	Shared Neighborhood Hits	50
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

HGS_MOUSE
θ value	θ > 10 (rank : 502)	NC score	0.084644 (rank : 516)
Query Neighborhood Hits	255	Target Neighborhood Hits	589	Shared Neighborhood Hits	48
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

HIP1R_HUMAN
θ value	θ > 10 (rank : 503)	NC score	0.088105 (rank : 476)
Query Neighborhood Hits	255	Target Neighborhood Hits	809	Shared Neighborhood Hits	105
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

HIP1R_MOUSE
θ value	θ > 10 (rank : 504)	NC score	0.091856 (rank : 440)
Query Neighborhood Hits	255	Target Neighborhood Hits	959	Shared Neighborhood Hits	108
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

HIP1_HUMAN
θ value	θ > 10 (rank : 505)	NC score	0.091832 (rank : 442)
Query Neighborhood Hits	255	Target Neighborhood Hits	1016	Shared Neighborhood Hits	107
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

HMMR_HUMAN
θ value	θ > 10 (rank : 506)	NC score	0.122612 (rank : 209)
Query Neighborhood Hits	255	Target Neighborhood Hits	1082	Shared Neighborhood Hits	124
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

HMMR_MOUSE
θ value	θ > 10 (rank : 507)	NC score	0.134075 (rank : 165)
Query Neighborhood Hits	255	Target Neighborhood Hits	1178	Shared Neighborhood Hits	131
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

HOME1_HUMAN
θ value	θ > 10 (rank : 508)	NC score	0.064868 (rank : 683)
Query Neighborhood Hits	255	Target Neighborhood Hits	564	Shared Neighborhood Hits	88
SwissProt Accessions	Q86YM7, O96003, Q86YM5	Gene names	HOMER1, SYN47
Domain Architecture
Description	Homer protein homolog 1.

HOME1_MOUSE
θ value	θ > 10 (rank : 509)	NC score	0.071264 (rank : 627)
Query Neighborhood Hits	255	Target Neighborhood Hits	630	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Z2Y3, Q8K3E1, Q8K4M8, Q9Z0E9, Q9Z216	Gene names	Homer1, Vesl1
Domain Architecture
Description	Homer protein homolog 1 (VASP/Ena-related gene up-regulated during seizure and LTP) (Vesl-1).

HOME2_HUMAN
θ value	θ > 10 (rank : 510)	NC score	0.067407 (rank : 663)
Query Neighborhood Hits	255	Target Neighborhood Hits	532	Shared Neighborhood Hits	79
SwissProt Accessions	Q9NSB8, O95269, O95349, Q9NSB6, Q9NSB7, Q9UNT7	Gene names	HOMER2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin).

HOME2_MOUSE
θ value	θ > 10 (rank : 511)	NC score	0.087153 (rank : 488)
Query Neighborhood Hits	255	Target Neighborhood Hits	882	Shared Neighborhood Hits	103
SwissProt Accessions	Q9QWW1, O89025, Q9Z0E4	Gene names	Homer2, Vesl2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).

HOOK1_HUMAN
θ value	θ > 10 (rank : 512)	NC score	0.125634 (rank : 199)
Query Neighborhood Hits	255	Target Neighborhood Hits	942	Shared Neighborhood Hits	118
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

HOOK1_MOUSE
θ value	θ > 10 (rank : 513)	NC score	0.124099 (rank : 205)
Query Neighborhood Hits	255	Target Neighborhood Hits	910	Shared Neighborhood Hits	121
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

HOOK3_HUMAN
θ value	θ > 10 (rank : 514)	NC score	0.125413 (rank : 200)
Query Neighborhood Hits	255	Target Neighborhood Hits	1070	Shared Neighborhood Hits	119
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

HOOK3_MOUSE
θ value	θ > 10 (rank : 515)	NC score	0.126797 (rank : 191)
Query Neighborhood Hits	255	Target Neighborhood Hits	1007	Shared Neighborhood Hits	119
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

IASPP_HUMAN
θ value	θ > 10 (rank : 516)	NC score	0.069196 (rank : 645)
Query Neighborhood Hits	255	Target Neighborhood Hits	688	Shared Neighborhood Hits	47
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

IASPP_MOUSE
θ value	θ > 10 (rank : 517)	NC score	0.073124 (rank : 613)
Query Neighborhood Hits	255	Target Neighborhood Hits	1024	Shared Neighborhood Hits	54
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

IDLC_HUMAN
θ value	θ > 10 (rank : 518)	NC score	0.057292 (rank : 777)
Query Neighborhood Hits	255	Target Neighborhood Hits	348	Shared Neighborhood Hits	65
SwissProt Accessions	O14645, Q5TGH0, Q7L0I5	Gene names	DNALI1
Domain Architecture	No domain graphic available
Description	Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal) (hp28).

IDLC_MOUSE
θ value	θ > 10 (rank : 519)	NC score	0.055135 (rank : 793)
Query Neighborhood Hits	255	Target Neighborhood Hits	321	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BVN8	Gene names	Dnali1
Domain Architecture	No domain graphic available
Description	Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal).

IF2P_HUMAN
θ value	θ > 10 (rank : 520)	NC score	0.070885 (rank : 629)
Query Neighborhood Hits	255	Target Neighborhood Hits	889	Shared Neighborhood Hits	85
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

IF3A_HUMAN
θ value	θ > 10 (rank : 521)	NC score	0.095619 (rank : 402)
Query Neighborhood Hits	255	Target Neighborhood Hits	875	Shared Neighborhood Hits	103
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

IF3A_MOUSE
θ value	θ > 10 (rank : 522)	NC score	0.098813 (rank : 364)
Query Neighborhood Hits	255	Target Neighborhood Hits	871	Shared Neighborhood Hits	104
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

IFT74_HUMAN
θ value	θ > 10 (rank : 523)	NC score	0.116894 (rank : 246)
Query Neighborhood Hits	255	Target Neighborhood Hits	949	Shared Neighborhood Hits	117
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

IFT74_MOUSE
θ value	θ > 10 (rank : 524)	NC score	0.111650 (rank : 278)
Query Neighborhood Hits	255	Target Neighborhood Hits	939	Shared Neighborhood Hits	123
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

IFT81_HUMAN
θ value	θ > 10 (rank : 525)	NC score	0.108310 (rank : 297)
Query Neighborhood Hits	255	Target Neighborhood Hits	893	Shared Neighborhood Hits	114
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

IFT81_MOUSE
θ value	θ > 10 (rank : 526)	NC score	0.114081 (rank : 259)
Query Neighborhood Hits	255	Target Neighborhood Hits	959	Shared Neighborhood Hits	114
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

IMMT_HUMAN
θ value	θ > 10 (rank : 527)	NC score	0.070601 (rank : 633)
Query Neighborhood Hits	255	Target Neighborhood Hits	494	Shared Neighborhood Hits	86
SwissProt Accessions	Q16891, Q14539, Q15092, Q68D41, Q69HW5, Q6IBL0, Q7Z3X1, Q8TAJ5, Q9P0V2	Gene names	IMMT, HMP, PIG4
Domain Architecture	No domain graphic available
Description	Mitochondrial inner membrane protein (Mitofilin) (p87/89) (Proliferation-inducing gene 4 protein).

IMMT_MOUSE
θ value	θ > 10 (rank : 528)	NC score	0.052486 (rank : 829)
Query Neighborhood Hits	255	Target Neighborhood Hits	326	Shared Neighborhood Hits	72
SwissProt Accessions	Q8CAQ8, Q66JS4, Q7TNE2, Q8C7V1, Q8CCI0, Q8CDA8, Q9D9F6	Gene names	Immt
Domain Architecture	No domain graphic available
Description	Mitochondrial inner membrane protein (Mitofilin).

INCE_HUMAN
θ value	θ > 10 (rank : 529)	NC score	0.098370 (rank : 367)
Query Neighborhood Hits	255	Target Neighborhood Hits	978	Shared Neighborhood Hits	105
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

INCE_MOUSE
θ value	θ > 10 (rank : 530)	NC score	0.097027 (rank : 384)
Query Neighborhood Hits	255	Target Neighborhood Hits	903	Shared Neighborhood Hits	111
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

INVO_HUMAN
θ value	θ > 10 (rank : 531)	NC score	0.110796 (rank : 285)
Query Neighborhood Hits	255	Target Neighborhood Hits	636	Shared Neighborhood Hits	92
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

INVO_MOUSE
θ value	θ > 10 (rank : 532)	NC score	0.063635 (rank : 701)
Query Neighborhood Hits	255	Target Neighborhood Hits	474	Shared Neighborhood Hits	65
SwissProt Accessions	P48997	Gene names	Ivl
Domain Architecture	No domain graphic available
Description	Involucrin.

JIP4_HUMAN
θ value	θ > 10 (rank : 533)	NC score	0.067116 (rank : 665)
Query Neighborhood Hits	255	Target Neighborhood Hits	585	Shared Neighborhood Hits	78
SwissProt Accessions	O60271, O60905, Q3KQU8, Q3MKM7, Q86WC7, Q86WC8, Q8IZX7, Q96II0, Q9H811	Gene names	SPAG9, HSS, KIAA0516, MAPK8IP4, SYD1
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (Human lung cancer protein 6) (HLC-6) (Proliferation-inducing protein 6) (Sperm-specific protein) (Sperm surface protein) (Protein highly expressed in testis) (PHET) (Sunday driver 1).

JIP4_MOUSE
θ value	θ > 10 (rank : 534)	NC score	0.063356 (rank : 707)
Query Neighborhood Hits	255	Target Neighborhood Hits	593	Shared Neighborhood Hits	77
SwissProt Accessions	Q58A65, Q3UH77, Q3UHF0, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2	Gene names	Spag9, Jip4, Jsap2, Kiaa0516, Mapk8ip4
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (JNK/SAPK-associated protein 2) (JSAP2).

K0494_HUMAN
θ value	θ > 10 (rank : 535)	NC score	0.060069 (rank : 744)
Query Neighborhood Hits	255	Target Neighborhood Hits	230	Shared Neighborhood Hits	56
SwissProt Accessions	O75071	Gene names	KIAA0494
Domain Architecture	No domain graphic available
Description	Uncharacterized calcium-binding protein KIAA0494.

K0494_MOUSE
θ value	θ > 10 (rank : 536)	NC score	0.056628 (rank : 781)
Query Neighborhood Hits	255	Target Neighborhood Hits	241	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BGQ6, Q3TQN6, Q8BJV7, Q8C0R1	Gene names	Kiaa0494
Domain Architecture	No domain graphic available
Description	Uncharacterized calcium-binding protein KIAA0494.

K0552_HUMAN
θ value	θ > 10 (rank : 537)	NC score	0.079989 (rank : 554)
Query Neighborhood Hits	255	Target Neighborhood Hits	442	Shared Neighborhood Hits	79
SwissProt Accessions	O60299	Gene names	KIAA0552
Domain Architecture
Description	Protein KIAA0552.

K0555_HUMAN
θ value	θ > 10 (rank : 538)	NC score	0.113447 (rank : 262)
Query Neighborhood Hits	255	Target Neighborhood Hits	880	Shared Neighborhood Hits	118
SwissProt Accessions	Q96AA8, O60302	Gene names	KIAA0555
Domain Architecture	No domain graphic available
Description	Protein KIAA0555.

KI20A_HUMAN
θ value	θ > 10 (rank : 539)	NC score	0.051499 (rank : 839)
Query Neighborhood Hits	255	Target Neighborhood Hits	321	Shared Neighborhood Hits	64
SwissProt Accessions	O95235	Gene names	KIF20A, RAB6KIFL
Domain Architecture
Description	Kinesin family member 20A (Rabkinesin-6) (Rab6-interacting kinesin- like protein) (GG10_2).

KIF11_HUMAN
θ value	θ > 10 (rank : 540)	NC score	0.075459 (rank : 591)
Query Neighborhood Hits	255	Target Neighborhood Hits	583	Shared Neighborhood Hits	100
SwissProt Accessions	P52732, Q15716, Q5VWX0	Gene names	KIF11, EG5, KNSL1
Domain Architecture
Description	Kinesin-like protein KIF11 (Kinesin-related motor protein Eg5) (Kinesin-like spindle protein HKSP) (Thyroid receptor-interacting protein 5) (TRIP5) (Kinesin-like protein 1).

KIF11_MOUSE
θ value	θ > 10 (rank : 541)	NC score	0.058249 (rank : 766)
Query Neighborhood Hits	255	Target Neighborhood Hits	446	Shared Neighborhood Hits	81
SwissProt Accessions	Q6P9P6, Q9Z1J0	Gene names	Kif11
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF11 (Kinesin-related motor protein Eg5).

KIF14_HUMAN
θ value	θ > 10 (rank : 542)	NC score	0.058628 (rank : 762)
Query Neighborhood Hits	255	Target Neighborhood Hits	732	Shared Neighborhood Hits	97
SwissProt Accessions	Q15058	Gene names	KIF14, KIAA0042
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF14.

KIF23_HUMAN
θ value	θ > 10 (rank : 543)	NC score	0.059689 (rank : 751)
Query Neighborhood Hits	255	Target Neighborhood Hits	618	Shared Neighborhood Hits	84
SwissProt Accessions	Q02241	Gene names	KIF23, KNSL5, MKLP1
Domain Architecture
Description	Kinesin-like protein KIF23 (Mitotic kinesin-like protein 1) (Kinesin- like protein 5).

KIF3A_HUMAN
θ value	θ > 10 (rank : 544)	NC score	0.064904 (rank : 682)
Query Neighborhood Hits	255	Target Neighborhood Hits	704	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Y496, Q86XE9, Q9Y6V4	Gene names	KIF3A, KIF3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

KIF3A_MOUSE
θ value	θ > 10 (rank : 545)	NC score	0.064278 (rank : 689)
Query Neighborhood Hits	255	Target Neighborhood Hits	715	Shared Neighborhood Hits	104
SwissProt Accessions	P28741	Gene names	Kif3a, Kif3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

KIF3B_HUMAN
θ value	θ > 10 (rank : 546)	NC score	0.053929 (rank : 809)
Query Neighborhood Hits	255	Target Neighborhood Hits	540	Shared Neighborhood Hits	90
SwissProt Accessions	O15066	Gene names	KIF3B, KIAA0359
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B) (HH0048).

KIF3B_MOUSE
θ value	θ > 10 (rank : 547)	NC score	0.053473 (rank : 813)
Query Neighborhood Hits	255	Target Neighborhood Hits	533	Shared Neighborhood Hits	88
SwissProt Accessions	Q61771	Gene names	Kif3b
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B).

KIF4A_HUMAN
θ value	θ > 10 (rank : 548)	NC score	0.091322 (rank : 445)
Query Neighborhood Hits	255	Target Neighborhood Hits	1159	Shared Neighborhood Hits	115
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

KIF4A_MOUSE
θ value	θ > 10 (rank : 549)	NC score	0.086286 (rank : 500)
Query Neighborhood Hits	255	Target Neighborhood Hits	1033	Shared Neighborhood Hits	111
SwissProt Accessions	P33174	Gene names	Kif4a, Kif4, Kns4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

KIF5C_HUMAN
θ value	θ > 10 (rank : 550)	NC score	0.093164 (rank : 428)
Query Neighborhood Hits	255	Target Neighborhood Hits	974	Shared Neighborhood Hits	121
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

KIF5C_MOUSE
θ value	θ > 10 (rank : 551)	NC score	0.093436 (rank : 422)
Query Neighborhood Hits	255	Target Neighborhood Hits	1040	Shared Neighborhood Hits	119
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

KIFC1_HUMAN
θ value	θ > 10 (rank : 552)	NC score	0.059495 (rank : 755)
Query Neighborhood Hits	255	Target Neighborhood Hits	545	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BW19, O60887, Q14834, Q9UQP7	Gene names	KIFC1, HSET, KNSL2
Domain Architecture
Description	Kinesin-like protein KIFC1 (Kinesin-like protein 2) (Kinesin-related protein HSET).

KIFC3_HUMAN
θ value	θ > 10 (rank : 553)	NC score	0.062823 (rank : 716)
Query Neighborhood Hits	255	Target Neighborhood Hits	619	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BVG8, O75299, Q8IUT3, Q96HW6	Gene names	KIFC3
Domain Architecture
Description	Kinesin-like protein KIFC3.

KIFC3_MOUSE
θ value	θ > 10 (rank : 554)	NC score	0.059990 (rank : 747)
Query Neighborhood Hits	255	Target Neighborhood Hits	571	Shared Neighborhood Hits	90
SwissProt Accessions	O35231, Q91YQ2	Gene names	Kifc3
Domain Architecture
Description	Kinesin-like protein KIFC3.

KINH_HUMAN
θ value	θ > 10 (rank : 555)	NC score	0.095444 (rank : 405)
Query Neighborhood Hits	255	Target Neighborhood Hits	1231	Shared Neighborhood Hits	126
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

KINH_MOUSE
θ value	θ > 10 (rank : 556)	NC score	0.090053 (rank : 458)
Query Neighborhood Hits	255	Target Neighborhood Hits	1082	Shared Neighborhood Hits	121
SwissProt Accessions	Q61768, O08711, Q61580	Gene names	Kif5b, Khcs, Kns1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

KMHN1_HUMAN
θ value	θ > 10 (rank : 557)	NC score	0.107655 (rank : 299)
Query Neighborhood Hits	255	Target Neighborhood Hits	950	Shared Neighborhood Hits	112
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

KNTC2_HUMAN
θ value	θ > 10 (rank : 558)	NC score	0.094724 (rank : 412)
Query Neighborhood Hits	255	Target Neighborhood Hits	673	Shared Neighborhood Hits	96
SwissProt Accessions	O14777, Q6PJX2	Gene names	KNTC2, HEC, HEC1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cancer protein) (Retinoblastoma-associated protein HEC).

KNTC2_MOUSE
θ value	θ > 10 (rank : 559)	NC score	0.094245 (rank : 416)
Query Neighborhood Hits	255	Target Neighborhood Hits	692	Shared Neighborhood Hits	101
SwissProt Accessions	Q9D0F1, Q3TQT6, Q3UWM5, Q99P70	Gene names	Kntc2, Hec1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (Kinetochore-associated protein 2).

KTN1_HUMAN
θ value	θ > 10 (rank : 560)	NC score	0.136502 (rank : 164)
Query Neighborhood Hits	255	Target Neighborhood Hits	1197	Shared Neighborhood Hits	122
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

LAMA2_MOUSE
θ value	θ > 10 (rank : 561)	NC score	0.063149 (rank : 712)
Query Neighborhood Hits	255	Target Neighborhood Hits	1198	Shared Neighborhood Hits	104
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA4_HUMAN
θ value	θ > 10 (rank : 562)	NC score	0.057136 (rank : 779)
Query Neighborhood Hits	255	Target Neighborhood Hits	708	Shared Neighborhood Hits	91
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMC1_HUMAN
θ value	θ > 10 (rank : 563)	NC score	0.052630 (rank : 826)
Query Neighborhood Hits	255	Target Neighborhood Hits	922	Shared Neighborhood Hits	103
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LASP1_HUMAN
θ value	θ > 10 (rank : 564)	NC score	0.085810 (rank : 505)
Query Neighborhood Hits	255	Target Neighborhood Hits	293	Shared Neighborhood Hits	44
SwissProt Accessions	Q14847, Q96ED2, Q96IG0	Gene names	LASP1, MLN50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

LASP1_MOUSE
θ value	θ > 10 (rank : 565)	NC score	0.083637 (rank : 528)
Query Neighborhood Hits	255	Target Neighborhood Hits	297	Shared Neighborhood Hits	44
SwissProt Accessions	Q61792, Q62416	Gene names	Lasp1, Mln50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

LBN_HUMAN
θ value	θ > 10 (rank : 566)	NC score	0.066580 (rank : 669)
Query Neighborhood Hits	255	Target Neighborhood Hits	308	Shared Neighborhood Hits	74
SwissProt Accessions	Q86UK5, Q86YT3, Q86YT4, Q8NG49	Gene names	EVC2, LBN
Domain Architecture	No domain graphic available
Description	Limbin.

LBN_MOUSE
θ value	θ > 10 (rank : 567)	NC score	0.067745 (rank : 656)
Query Neighborhood Hits	255	Target Neighborhood Hits	310	Shared Neighborhood Hits	74
SwissProt Accessions	Q8K1G2, Q8BRF3	Gene names	Evc2, Lbn
Domain Architecture	No domain graphic available
Description	Limbin.

LETM1_HUMAN
θ value	θ > 10 (rank : 568)	NC score	0.073926 (rank : 602)
Query Neighborhood Hits	255	Target Neighborhood Hits	338	Shared Neighborhood Hits	73
SwissProt Accessions	O95202, Q9UF65	Gene names	LETM1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

LETM1_MOUSE
θ value	θ > 10 (rank : 569)	NC score	0.061651 (rank : 729)
Query Neighborhood Hits	255	Target Neighborhood Hits	240	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Z2I0, Q5PQC5, Q7TMK8, Q80ZX6, Q8CGJ3, Q8K5E5	Gene names	Letm1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

LIPA1_HUMAN
θ value	θ > 10 (rank : 570)	NC score	0.107511 (rank : 301)
Query Neighborhood Hits	255	Target Neighborhood Hits	1294	Shared Neighborhood Hits	118
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

LIPA3_MOUSE
θ value	θ > 10 (rank : 571)	NC score	0.088559 (rank : 472)
Query Neighborhood Hits	255	Target Neighborhood Hits	636	Shared Neighborhood Hits	96
SwissProt Accessions	P60469	Gene names	Ppfia3
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

LIPB1_HUMAN
θ value	θ > 10 (rank : 572)	NC score	0.085640 (rank : 508)
Query Neighborhood Hits	255	Target Neighborhood Hits	640	Shared Neighborhood Hits	99
SwissProt Accessions	Q86W92, O75336, Q86X70, Q9NY03, Q9ULJ0	Gene names	PPFIBP1, KIAA1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2).

LIPB1_MOUSE
θ value	θ > 10 (rank : 573)	NC score	0.086329 (rank : 498)
Query Neighborhood Hits	255	Target Neighborhood Hits	727	Shared Neighborhood Hits	109
SwissProt Accessions	Q8C8U0, Q69ZN5, Q6GQV3, Q80VB4, Q9CUT7	Gene names	Ppfibp1, Kiaa1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1).

LIPB2_HUMAN
θ value	θ > 10 (rank : 574)	NC score	0.072233 (rank : 620)
Query Neighborhood Hits	255	Target Neighborhood Hits	599	Shared Neighborhood Hits	89
SwissProt Accessions	Q8ND30, O75337, Q8WW26	Gene names	PPFIBP2
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2).

LIPB2_MOUSE
θ value	θ > 10 (rank : 575)	NC score	0.074984 (rank : 594)
Query Neighborhood Hits	255	Target Neighborhood Hits	570	Shared Neighborhood Hits	86
SwissProt Accessions	O35711, Q7TMG4, Q8CBS6, Q99KX6	Gene names	Ppfibp2, Cclp1
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2) (Coiled-coil-like protein 1).

LMNA_HUMAN
θ value	θ > 10 (rank : 576)	NC score	0.063425 (rank : 705)
Query Neighborhood Hits	255	Target Neighborhood Hits	653	Shared Neighborhood Hits	104
SwissProt Accessions	P02545, P02546, Q969I8, Q96JA2	Gene names	LMNA, LMN1
Domain Architecture
Description	Lamin-A/C (70 kDa lamin) (NY-REN-32 antigen).

LMNA_MOUSE
θ value	θ > 10 (rank : 577)	NC score	0.063554 (rank : 703)
Query Neighborhood Hits	255	Target Neighborhood Hits	661	Shared Neighborhood Hits	104
SwissProt Accessions	P48678, P11516, P97859, Q3TIH0, Q3TTS8, Q3UCA0, Q3UCJ8, Q91WF2, Q9DC21	Gene names	Lmna, Lmn1
Domain Architecture
Description	Lamin-A/C.

LMNB1_HUMAN
θ value	θ > 10 (rank : 578)	NC score	0.064586 (rank : 687)
Query Neighborhood Hits	255	Target Neighborhood Hits	714	Shared Neighborhood Hits	104
SwissProt Accessions	P20700, Q3SYN7, Q96EI6	Gene names	LMNB1, LMN2, LMNB
Domain Architecture
Description	Lamin-B1.

LMNB1_MOUSE
θ value	θ > 10 (rank : 579)	NC score	0.063968 (rank : 695)
Query Neighborhood Hits	255	Target Neighborhood Hits	719	Shared Neighborhood Hits	101
SwissProt Accessions	P14733, Q61791	Gene names	Lmnb1
Domain Architecture
Description	Lamin-B1.

LMNB2_HUMAN
θ value	θ > 10 (rank : 580)	NC score	0.063274 (rank : 709)
Query Neighborhood Hits	255	Target Neighborhood Hits	723	Shared Neighborhood Hits	105
SwissProt Accessions	Q03252, O75292, Q14734, Q96DF6	Gene names	LMNB2, LMN2
Domain Architecture
Description	Lamin-B2.

LMNB2_MOUSE
θ value	θ > 10 (rank : 581)	NC score	0.056487 (rank : 782)
Query Neighborhood Hits	255	Target Neighborhood Hits	674	Shared Neighborhood Hits	96
SwissProt Accessions	P21619, P48680, Q8CGB1	Gene names	Lmnb2
Domain Architecture
Description	Lamin-B2.

LMO7_HUMAN
θ value	θ > 10 (rank : 582)	NC score	0.096270 (rank : 393)
Query Neighborhood Hits	255	Target Neighborhood Hits	507	Shared Neighborhood Hits	69
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

LRC45_HUMAN
θ value	θ > 10 (rank : 583)	NC score	0.100861 (rank : 348)
Query Neighborhood Hits	255	Target Neighborhood Hits	933	Shared Neighborhood Hits	112
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

LRC45_MOUSE
θ value	θ > 10 (rank : 584)	NC score	0.094346 (rank : 414)
Query Neighborhood Hits	255	Target Neighborhood Hits	959	Shared Neighborhood Hits	108
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

LRRF1_HUMAN
θ value	θ > 10 (rank : 585)	NC score	0.052607 (rank : 828)
Query Neighborhood Hits	255	Target Neighborhood Hits	625	Shared Neighborhood Hits	71
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

LRRF2_HUMAN
θ value	θ > 10 (rank : 586)	NC score	0.094196 (rank : 417)
Query Neighborhood Hits	255	Target Neighborhood Hits	791	Shared Neighborhood Hits	102
SwissProt Accessions	Q9Y608, Q68CV3, Q9NXH5	Gene names	LRRFIP2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

LRRF2_MOUSE
θ value	θ > 10 (rank : 587)	NC score	0.087537 (rank : 484)
Query Neighborhood Hits	255	Target Neighborhood Hits	556	Shared Neighborhood Hits	88
SwissProt Accessions	Q91WK0, Q8BVD1, Q9CU89	Gene names	Lrrfip2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

LUZP1_HUMAN
θ value	θ > 10 (rank : 588)	NC score	0.084301 (rank : 519)
Query Neighborhood Hits	255	Target Neighborhood Hits	739	Shared Neighborhood Hits	94
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

LUZP1_MOUSE
θ value	θ > 10 (rank : 589)	NC score	0.100202 (rank : 355)
Query Neighborhood Hits	255	Target Neighborhood Hits	940	Shared Neighborhood Hits	109
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

LZTS1_HUMAN
θ value	θ > 10 (rank : 590)	NC score	0.084086 (rank : 522)
Query Neighborhood Hits	255	Target Neighborhood Hits	532	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Y250, Q9Y5V7, Q9Y5V8, Q9Y5V9, Q9Y5W0, Q9Y5W1, Q9Y5W2	Gene names	LZTS1, FEZ1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

LZTS1_MOUSE
θ value	θ > 10 (rank : 591)	NC score	0.077445 (rank : 571)
Query Neighborhood Hits	255	Target Neighborhood Hits	540	Shared Neighborhood Hits	86
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

LZTS2_HUMAN
θ value	θ > 10 (rank : 592)	NC score	0.072176 (rank : 621)
Query Neighborhood Hits	255	Target Neighborhood Hits	427	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BRK4, Q8N3I0, Q96J79, Q96JL2	Gene names	LZTS2, KIAA1813, LAPSER1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 2 (Protein LAPSER1).

LZTS2_MOUSE
θ value	θ > 10 (rank : 593)	NC score	0.074099 (rank : 600)
Query Neighborhood Hits	255	Target Neighborhood Hits	423	Shared Neighborhood Hits	78
SwissProt Accessions	Q91YU6, Q569X6	Gene names	Lzts2, Kiaa1813
Domain Architecture
Description	Leucine zipper putative tumor suppressor 2.

M3KL4_HUMAN
θ value	θ > 10 (rank : 594)	NC score	0.053328 (rank : 816)
Query Neighborhood Hits	255	Target Neighborhood Hits	1087	Shared Neighborhood Hits	80
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

MACOI_HUMAN
θ value	θ > 10 (rank : 595)	NC score	0.087220 (rank : 486)
Query Neighborhood Hits	255	Target Neighborhood Hits	650	Shared Neighborhood Hits	97
SwissProt Accessions	Q8N5G2, Q2TLX5, Q2TLX6, Q9NVG6	Gene names	TMEM57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57).

MACOI_MOUSE
θ value	θ > 10 (rank : 596)	NC score	0.087240 (rank : 485)
Query Neighborhood Hits	255	Target Neighborhood Hits	620	Shared Neighborhood Hits	99
SwissProt Accessions	Q7TQE6	Gene names	Tmem57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57) (Brain-specific adaptor protein C61).

MAP1A_HUMAN
θ value	θ > 10 (rank : 597)	NC score	0.083552 (rank : 529)
Query Neighborhood Hits	255	Target Neighborhood Hits	1626	Shared Neighborhood Hits	116
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MAP9_HUMAN
θ value	θ > 10 (rank : 598)	NC score	0.058321 (rank : 765)
Query Neighborhood Hits	255	Target Neighborhood Hits	518	Shared Neighborhood Hits	61
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

MAP9_MOUSE
θ value	θ > 10 (rank : 599)	NC score	0.062254 (rank : 722)
Query Neighborhood Hits	255	Target Neighborhood Hits	529	Shared Neighborhood Hits	68
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

MD1L1_HUMAN
θ value	θ > 10 (rank : 600)	NC score	0.112702 (rank : 269)
Query Neighborhood Hits	255	Target Neighborhood Hits	893	Shared Neighborhood Hits	115
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

MD1L1_MOUSE
θ value	θ > 10 (rank : 601)	NC score	0.113871 (rank : 260)
Query Neighborhood Hits	255	Target Neighborhood Hits	1001	Shared Neighborhood Hits	116
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

MERL_HUMAN
θ value	θ > 10 (rank : 602)	NC score	0.051419 (rank : 842)
Query Neighborhood Hits	255	Target Neighborhood Hits	532	Shared Neighborhood Hits	87
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

MERL_MOUSE
θ value	θ > 10 (rank : 603)	NC score	0.052118 (rank : 833)
Query Neighborhood Hits	255	Target Neighborhood Hits	524	Shared Neighborhood Hits	87
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

MFAP1_MOUSE
θ value	θ > 10 (rank : 604)	NC score	0.058180 (rank : 769)
Query Neighborhood Hits	255	Target Neighborhood Hits	353	Shared Neighborhood Hits	58
SwissProt Accessions	Q9CQU1, Q3TU29, Q8CCL1, Q9CSJ5	Gene names	Mfap1
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 1.

MIA_HUMAN
θ value	θ > 10 (rank : 605)	NC score	0.056470 (rank : 783)
Query Neighborhood Hits	255	Target Neighborhood Hits	19	Shared Neighborhood Hits	9
SwissProt Accessions	Q16674	Gene names	MIA
Domain Architecture
Description	Melanoma-derived growth regulatory protein precursor (Melanoma inhibitory activity).

MIA_MOUSE
θ value	θ > 10 (rank : 606)	NC score	0.057419 (rank : 776)
Query Neighborhood Hits	255	Target Neighborhood Hits	17	Shared Neighborhood Hits	7
SwissProt Accessions	Q61865, O09086, P97495	Gene names	Mia, Cdrap, Mia1
Domain Architecture
Description	Melanoma-derived growth regulatory protein precursor (Melanoma inhibitory activity) (Cartilage-derived retinoic acid-sensitive protein) (CD-RAP).

MICA1_HUMAN
θ value	θ > 10 (rank : 607)	NC score	0.070611 (rank : 632)
Query Neighborhood Hits	255	Target Neighborhood Hits	279	Shared Neighborhood Hits	47
SwissProt Accessions	Q8TDZ2, Q7Z633, Q8IVS9, Q96G47, Q9H6X6, Q9H7I0, Q9HAA1, Q9UFF7	Gene names	MICAL1, MICAL, NICAL
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

MICA1_MOUSE
θ value	θ > 10 (rank : 608)	NC score	0.088819 (rank : 469)
Query Neighborhood Hits	255	Target Neighborhood Hits	400	Shared Neighborhood Hits	82
SwissProt Accessions	Q8VDP3	Gene names	Mical1, Mical, Nical
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

MICA2_MOUSE
θ value	θ > 10 (rank : 609)	NC score	0.076985 (rank : 575)
Query Neighborhood Hits	255	Target Neighborhood Hits	144	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BML1, Q3UPU6	Gene names	Mical2
Domain Architecture
Description	Protein MICAL-2.

MICA3_HUMAN
θ value	θ > 10 (rank : 610)	NC score	0.075959 (rank : 585)
Query Neighborhood Hits	255	Target Neighborhood Hits	160	Shared Neighborhood Hits	24
SwissProt Accessions	Q7RTP6, Q6ICK4, Q9P2I3	Gene names	MICAL3, KIAA1364
Domain Architecture
Description	Protein MICAL-3.

MICA3_MOUSE
θ value	θ > 10 (rank : 611)	NC score	0.078465 (rank : 562)
Query Neighborhood Hits	255	Target Neighborhood Hits	104	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CJ19, Q80TE8, Q8BXB1	Gene names	Mical3, Kiaa1364
Domain Architecture
Description	Protein MICAL-3.

MILK1_HUMAN
θ value	θ > 10 (rank : 612)	NC score	0.095274 (rank : 408)
Query Neighborhood Hits	255	Target Neighborhood Hits	427	Shared Neighborhood Hits	34
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MILK1_MOUSE
θ value	θ > 10 (rank : 613)	NC score	0.090428 (rank : 454)
Query Neighborhood Hits	255	Target Neighborhood Hits	788	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MILK2_HUMAN
θ value	θ > 10 (rank : 614)	NC score	0.097820 (rank : 376)
Query Neighborhood Hits	255	Target Neighborhood Hits	457	Shared Neighborhood Hits	44
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

MIPO1_HUMAN
θ value	θ > 10 (rank : 615)	NC score	0.096071 (rank : 396)
Query Neighborhood Hits	255	Target Neighborhood Hits	486	Shared Neighborhood Hits	83
SwissProt Accessions	Q8TD10, Q7Z3J0, Q8IV14	Gene names	MIPOL1
Domain Architecture	No domain graphic available
Description	Mirror-image polydactyly gene 1 protein.

MMRN1_HUMAN
θ value	θ > 10 (rank : 616)	NC score	0.085895 (rank : 504)
Query Neighborhood Hits	255	Target Neighborhood Hits	636	Shared Neighborhood Hits	81
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

MMRN2_HUMAN
θ value	θ > 10 (rank : 617)	NC score	0.076335 (rank : 579)
Query Neighborhood Hits	255	Target Neighborhood Hits	400	Shared Neighborhood Hits	77
SwissProt Accessions	Q9H8L6, Q6P2N2	Gene names	MMRN2, EMILIN3
Domain Architecture
Description	Multimerin-2 precursor (EMILIN-3) (Elastin microfibril interface located protein 3) (Elastin microfibril interfacer 3) (EndoGlyx-1 p125/p140 subunit).

MOES_HUMAN
θ value	θ > 10 (rank : 618)	NC score	0.077814 (rank : 569)
Query Neighborhood Hits	255	Target Neighborhood Hits	892	Shared Neighborhood Hits	107
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MOES_MOUSE
θ value	θ > 10 (rank : 619)	NC score	0.078964 (rank : 560)
Query Neighborhood Hits	255	Target Neighborhood Hits	923	Shared Neighborhood Hits	108
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MORC3_HUMAN
θ value	θ > 10 (rank : 620)	NC score	0.075569 (rank : 590)
Query Neighborhood Hits	255	Target Neighborhood Hits	489	Shared Neighborhood Hits	96
SwissProt Accessions	Q14149, Q9UEZ2	Gene names	MORC3, KIAA0136, ZCWCC3
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 3 (Zinc finger CW-type coiled- coil domain protein 3).

MPP9_HUMAN
θ value	θ > 10 (rank : 621)	NC score	0.098090 (rank : 372)
Query Neighborhood Hits	255	Target Neighborhood Hits	529	Shared Neighborhood Hits	91
SwissProt Accessions	Q99550, Q9H976	Gene names	MPHOSPH9, MPP9
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 9.

MRCKB_MOUSE
θ value	θ > 10 (rank : 622)	NC score	0.080670 (rank : 549)
Query Neighborhood Hits	255	Target Neighborhood Hits	2180	Shared Neighborhood Hits	154
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MRCKG_HUMAN
θ value	θ > 10 (rank : 623)	NC score	0.050363 (rank : 855)
Query Neighborhood Hits	255	Target Neighborhood Hits	1519	Shared Neighborhood Hits	119
SwissProt Accessions	Q6DT37, O00565	Gene names	CDC42BPG
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

MRCKG_MOUSE
θ value	θ > 10 (rank : 624)	NC score	0.051073 (rank : 847)
Query Neighborhood Hits	255	Target Neighborhood Hits	1466	Shared Neighborhood Hits	122
SwissProt Accessions	Q80UW5	Gene names	Cdc42bpg
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

MRIP_HUMAN
θ value	θ > 10 (rank : 625)	NC score	0.069332 (rank : 643)
Query Neighborhood Hits	255	Target Neighborhood Hits	578	Shared Neighborhood Hits	82
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

MRIP_MOUSE
θ value	θ > 10 (rank : 626)	NC score	0.068712 (rank : 650)
Query Neighborhood Hits	255	Target Neighborhood Hits	569	Shared Neighborhood Hits	82
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

MY18A_HUMAN
θ value	θ > 10 (rank : 627)	NC score	0.109053 (rank : 294)
Query Neighborhood Hits	255	Target Neighborhood Hits	1929	Shared Neighborhood Hits	138
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MY18A_MOUSE
θ value	θ > 10 (rank : 628)	NC score	0.103626 (rank : 331)
Query Neighborhood Hits	255	Target Neighborhood Hits	1989	Shared Neighborhood Hits	136
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MY18B_HUMAN
θ value	θ > 10 (rank : 629)	NC score	0.089192 (rank : 464)
Query Neighborhood Hits	255	Target Neighborhood Hits	1299	Shared Neighborhood Hits	116
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

MYH10_HUMAN
θ value	θ > 10 (rank : 630)	NC score	0.106172 (rank : 312)
Query Neighborhood Hits	255	Target Neighborhood Hits	1620	Shared Neighborhood Hits	138
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH11_HUMAN
θ value	θ > 10 (rank : 631)	NC score	0.104815 (rank : 327)
Query Neighborhood Hits	255	Target Neighborhood Hits	1806	Shared Neighborhood Hits	139
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH11_MOUSE
θ value	θ > 10 (rank : 632)	NC score	0.102860 (rank : 337)
Query Neighborhood Hits	255	Target Neighborhood Hits	1777	Shared Neighborhood Hits	139
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH14_HUMAN
θ value	θ > 10 (rank : 633)	NC score	0.086164 (rank : 501)
Query Neighborhood Hits	255	Target Neighborhood Hits	995	Shared Neighborhood Hits	109
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYH14_MOUSE
θ value	θ > 10 (rank : 634)	NC score	0.095413 (rank : 406)
Query Neighborhood Hits	255	Target Neighborhood Hits	1225	Shared Neighborhood Hits	126
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYH1_HUMAN
θ value	θ > 10 (rank : 635)	NC score	0.100808 (rank : 350)
Query Neighborhood Hits	255	Target Neighborhood Hits	1478	Shared Neighborhood Hits	126
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

MYH1_MOUSE
θ value	θ > 10 (rank : 636)	NC score	0.099811 (rank : 359)
Query Neighborhood Hits	255	Target Neighborhood Hits	1461	Shared Neighborhood Hits	127
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

MYH4_HUMAN
θ value	θ > 10 (rank : 637)	NC score	0.099242 (rank : 362)
Query Neighborhood Hits	255	Target Neighborhood Hits	1377	Shared Neighborhood Hits	130
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

MYH4_MOUSE
θ value	θ > 10 (rank : 638)	NC score	0.097923 (rank : 373)
Query Neighborhood Hits	255	Target Neighborhood Hits	1476	Shared Neighborhood Hits	130
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

MYH6_HUMAN
θ value	θ > 10 (rank : 639)	NC score	0.100042 (rank : 356)
Query Neighborhood Hits	255	Target Neighborhood Hits	1426	Shared Neighborhood Hits	130
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH6_MOUSE
θ value	θ > 10 (rank : 640)	NC score	0.103482 (rank : 333)
Query Neighborhood Hits	255	Target Neighborhood Hits	1501	Shared Neighborhood Hits	133
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH7_HUMAN
θ value	θ > 10 (rank : 641)	NC score	0.105396 (rank : 319)
Query Neighborhood Hits	255	Target Neighborhood Hits	1559	Shared Neighborhood Hits	133
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

MYH9_HUMAN
θ value	θ > 10 (rank : 642)	NC score	0.099461 (rank : 361)
Query Neighborhood Hits	255	Target Neighborhood Hits	1762	Shared Neighborhood Hits	140
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH9_MOUSE
θ value	θ > 10 (rank : 643)	NC score	0.097531 (rank : 378)
Query Neighborhood Hits	255	Target Neighborhood Hits	1829	Shared Neighborhood Hits	140
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYO1E_HUMAN
θ value	θ > 10 (rank : 644)	NC score	0.068254 (rank : 654)
Query Neighborhood Hits	255	Target Neighborhood Hits	293	Shared Neighborhood Hits	55
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

MYO1F_HUMAN
θ value	θ > 10 (rank : 645)	NC score	0.069237 (rank : 644)
Query Neighborhood Hits	255	Target Neighborhood Hits	275	Shared Neighborhood Hits	54
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

MYO1F_MOUSE
θ value	θ > 10 (rank : 646)	NC score	0.070391 (rank : 634)
Query Neighborhood Hits	255	Target Neighborhood Hits	262	Shared Neighborhood Hits	54
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

MYO5A_HUMAN
θ value	θ > 10 (rank : 647)	NC score	0.064260 (rank : 690)
Query Neighborhood Hits	255	Target Neighborhood Hits	1092	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

MYO5A_MOUSE
θ value	θ > 10 (rank : 648)	NC score	0.062677 (rank : 718)
Query Neighborhood Hits	255	Target Neighborhood Hits	1117	Shared Neighborhood Hits	105
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

MYO5B_HUMAN
θ value	θ > 10 (rank : 649)	NC score	0.060043 (rank : 745)
Query Neighborhood Hits	255	Target Neighborhood Hits	911	Shared Neighborhood Hits	102
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

NAF1_HUMAN
θ value	θ > 10 (rank : 650)	NC score	0.094583 (rank : 413)
Query Neighborhood Hits	255	Target Neighborhood Hits	937	Shared Neighborhood Hits	101
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

NAF1_MOUSE
θ value	θ > 10 (rank : 651)	NC score	0.096585 (rank : 389)
Query Neighborhood Hits	255	Target Neighborhood Hits	852	Shared Neighborhood Hits	100
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

NCF2_HUMAN
θ value	θ > 10 (rank : 652)	NC score	0.157220 (rank : 122)
Query Neighborhood Hits	255	Target Neighborhood Hits	229	Shared Neighborhood Hits	50
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

NCF4_HUMAN
θ value	θ > 10 (rank : 653)	NC score	0.151695 (rank : 131)
Query Neighborhood Hits	255	Target Neighborhood Hits	161	Shared Neighborhood Hits	37
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

NCF4_MOUSE
θ value	θ > 10 (rank : 654)	NC score	0.154471 (rank : 127)
Query Neighborhood Hits	255	Target Neighborhood Hits	177	Shared Neighborhood Hits	39
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

NCK1_HUMAN
θ value	θ > 10 (rank : 655)	NC score	0.152362 (rank : 130)
Query Neighborhood Hits	255	Target Neighborhood Hits	312	Shared Neighborhood Hits	51
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

NCK2_HUMAN
θ value	θ > 10 (rank : 656)	NC score	0.147449 (rank : 147)
Query Neighborhood Hits	255	Target Neighborhood Hits	310	Shared Neighborhood Hits	51
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

NDE1_HUMAN
θ value	θ > 10 (rank : 657)	NC score	0.082778 (rank : 538)
Query Neighborhood Hits	255	Target Neighborhood Hits	823	Shared Neighborhood Hits	102
SwissProt Accessions	Q9NXR1, Q49AQ2	Gene names	NDE1, NUDE
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE).

NDE1_MOUSE
θ value	θ > 10 (rank : 658)	NC score	0.069037 (rank : 646)
Query Neighborhood Hits	255	Target Neighborhood Hits	602	Shared Neighborhood Hits	88
SwissProt Accessions	Q9CZA6, Q3UBS6, Q3UIC1, Q9ERR0	Gene names	Nde1, Nude
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE) (mNudE).

NDEL1_HUMAN
θ value	θ > 10 (rank : 659)	NC score	0.060560 (rank : 738)
Query Neighborhood Hits	255	Target Neighborhood Hits	415	Shared Neighborhood Hits	72
SwissProt Accessions	Q9GZM8, Q86T80, Q8TAR7, Q9UH50	Gene names	NDEL1, EOPA, MITAP1, NUDEL
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE-like 1 (Protein Nudel) (Mitosin- associated protein 1).

NDEL1_MOUSE
θ value	θ > 10 (rank : 660)	NC score	0.060007 (rank : 746)
Query Neighborhood Hits	255	Target Neighborhood Hits	420	Shared Neighborhood Hits	73
SwissProt Accessions	Q9ERR1, Q9D0Q4, Q9EPT6	Gene names	Ndel1, Nudel
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE-like 1 (Protein Nudel) (Protein mNudE-like) (mNudE-L).

NEB1_HUMAN
θ value	θ > 10 (rank : 661)	NC score	0.062206 (rank : 723)
Query Neighborhood Hits	255	Target Neighborhood Hits	829	Shared Neighborhood Hits	90
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

NEB2_HUMAN
θ value	θ > 10 (rank : 662)	NC score	0.075588 (rank : 589)
Query Neighborhood Hits	255	Target Neighborhood Hits	883	Shared Neighborhood Hits	103
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_MOUSE
θ value	θ > 10 (rank : 663)	NC score	0.077918 (rank : 567)
Query Neighborhood Hits	255	Target Neighborhood Hits	889	Shared Neighborhood Hits	104
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEBL_HUMAN
θ value	θ > 10 (rank : 664)	NC score	0.115269 (rank : 253)
Query Neighborhood Hits	255	Target Neighborhood Hits	457	Shared Neighborhood Hits	92
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

NEBU_HUMAN
θ value	θ > 10 (rank : 665)	NC score	0.084925 (rank : 513)
Query Neighborhood Hits	255	Target Neighborhood Hits	420	Shared Neighborhood Hits	75
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

NEMO_HUMAN
θ value	θ > 10 (rank : 666)	NC score	0.101605 (rank : 344)
Query Neighborhood Hits	255	Target Neighborhood Hits	820	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

NEST_HUMAN
θ value	θ > 10 (rank : 667)	NC score	0.077835 (rank : 568)
Query Neighborhood Hits	255	Target Neighborhood Hits	1305	Shared Neighborhood Hits	113
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

NFM_HUMAN
θ value	θ > 10 (rank : 668)	NC score	0.058199 (rank : 768)
Query Neighborhood Hits	255	Target Neighborhood Hits	1328	Shared Neighborhood Hits	118
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

NFM_MOUSE
θ value	θ > 10 (rank : 669)	NC score	0.058440 (rank : 764)
Query Neighborhood Hits	255	Target Neighborhood Hits	1159	Shared Neighborhood Hits	116
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

NOXO1_HUMAN
θ value	θ > 10 (rank : 670)	NC score	0.098134 (rank : 371)
Query Neighborhood Hits	255	Target Neighborhood Hits	100	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NFA2, Q86YM1, Q8NFA3, Q96B73	Gene names	NOXO1, P41NOX
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Nox-organizing protein 1) (NADPH oxidase regulatory protein).

NOXO1_MOUSE
θ value	θ > 10 (rank : 671)	NC score	0.095980 (rank : 397)
Query Neighborhood Hits	255	Target Neighborhood Hits	114	Shared Neighborhood Hits	30
SwissProt Accessions	Q8VCM2, Q3TZA4, Q8BH41, Q9D747	Gene names	Noxo1, Snx28
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Sorting nexin-28).

NPHP1_HUMAN
θ value	θ > 10 (rank : 672)	NC score	0.100556 (rank : 351)
Query Neighborhood Hits	255	Target Neighborhood Hits	288	Shared Neighborhood Hits	63
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

NPHP1_MOUSE
θ value	θ > 10 (rank : 673)	NC score	0.129922 (rank : 176)
Query Neighborhood Hits	255	Target Neighborhood Hits	267	Shared Neighborhood Hits	59
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

NTBP1_MOUSE
θ value	θ > 10 (rank : 674)	NC score	0.051112 (rank : 846)
Query Neighborhood Hits	255	Target Neighborhood Hits	528	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BRM2, Q8CAA8	Gene names	Scyl1bp1, Ntklbp1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like-binding protein 1 (NTKL-binding protein 1) (NTKL-BP1) (mNTKL-BP1) (SCY1-like 1-binding protein 1) (SCYL1-binding protein 1) (SCYL1-BP1).

NUF2_HUMAN
θ value	θ > 10 (rank : 675)	NC score	0.093877 (rank : 419)
Query Neighborhood Hits	255	Target Neighborhood Hits	661	Shared Neighborhood Hits	95
SwissProt Accessions	Q9BZD4, Q8WU69, Q96HJ4, Q96Q78	Gene names	CDCA1, NUF2, NUF2R
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1).

NUF2_MOUSE
θ value	θ > 10 (rank : 676)	NC score	0.099871 (rank : 358)
Query Neighborhood Hits	255	Target Neighborhood Hits	585	Shared Neighborhood Hits	95
SwissProt Accessions	Q99P69, Q8BTK7, Q8VE05, Q9CST5	Gene names	Cdca1, Nuf2r
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (Cell division cycle-associated protein 1).

NUP88_HUMAN
θ value	θ > 10 (rank : 677)	NC score	0.052320 (rank : 832)
Query Neighborhood Hits	255	Target Neighborhood Hits	354	Shared Neighborhood Hits	65
SwissProt Accessions	Q99567, Q9BWE5	Gene names	NUP88
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup88 (Nucleoporin Nup88) (88 kDa nuclear pore complex protein).

OFD1_HUMAN
θ value	θ > 10 (rank : 678)	NC score	0.099754 (rank : 360)
Query Neighborhood Hits	255	Target Neighborhood Hits	753	Shared Neighborhood Hits	105
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

OPTN_HUMAN
θ value	θ > 10 (rank : 679)	NC score	0.102109 (rank : 341)
Query Neighborhood Hits	255	Target Neighborhood Hits	827	Shared Neighborhood Hits	97
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

OPTN_MOUSE
θ value	θ > 10 (rank : 680)	NC score	0.112489 (rank : 273)
Query Neighborhood Hits	255	Target Neighborhood Hits	1120	Shared Neighborhood Hits	115
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

OSTF1_HUMAN
θ value	θ > 10 (rank : 681)	NC score	0.107178 (rank : 305)
Query Neighborhood Hits	255	Target Neighborhood Hits	466	Shared Neighborhood Hits	46
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

OSTF1_MOUSE
θ value	θ > 10 (rank : 682)	NC score	0.105792 (rank : 318)
Query Neighborhood Hits	255	Target Neighborhood Hits	467	Shared Neighborhood Hits	46
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

P55G_HUMAN
θ value	θ > 10 (rank : 683)	NC score	0.081690 (rank : 542)
Query Neighborhood Hits	255	Target Neighborhood Hits	451	Shared Neighborhood Hits	82
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P55G_MOUSE
θ value	θ > 10 (rank : 684)	NC score	0.080901 (rank : 547)
Query Neighborhood Hits	255	Target Neighborhood Hits	401	Shared Neighborhood Hits	81
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P85A_HUMAN
θ value	θ > 10 (rank : 685)	NC score	0.075807 (rank : 586)
Query Neighborhood Hits	255	Target Neighborhood Hits	479	Shared Neighborhood Hits	78
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85A_MOUSE
θ value	θ > 10 (rank : 686)	NC score	0.069763 (rank : 638)
Query Neighborhood Hits	255	Target Neighborhood Hits	435	Shared Neighborhood Hits	67
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85B_HUMAN
θ value	θ > 10 (rank : 687)	NC score	0.090149 (rank : 456)
Query Neighborhood Hits	255	Target Neighborhood Hits	543	Shared Neighborhood Hits	92
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

P85B_MOUSE
θ value	θ > 10 (rank : 688)	NC score	0.086864 (rank : 492)
Query Neighborhood Hits	255	Target Neighborhood Hits	519	Shared Neighborhood Hits	90
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PACN1_HUMAN
θ value	θ > 10 (rank : 689)	NC score	0.093494 (rank : 421)
Query Neighborhood Hits	255	Target Neighborhood Hits	320	Shared Neighborhood Hits	70
SwissProt Accessions	Q9BY11, Q9P2G8	Gene names	PACSIN1, KIAA1379
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PACN1_MOUSE
θ value	θ > 10 (rank : 690)	NC score	0.087192 (rank : 487)
Query Neighborhood Hits	255	Target Neighborhood Hits	283	Shared Neighborhood Hits	55
SwissProt Accessions	Q61644	Gene names	Pacsin1, Pacsin
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PACN2_HUMAN
θ value	θ > 10 (rank : 691)	NC score	0.097004 (rank : 386)
Query Neighborhood Hits	255	Target Neighborhood Hits	339	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PACN2_MOUSE
θ value	θ > 10 (rank : 692)	NC score	0.096433 (rank : 392)
Query Neighborhood Hits	255	Target Neighborhood Hits	382	Shared Neighborhood Hits	72
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PACN3_HUMAN
θ value	θ > 10 (rank : 693)	NC score	0.089927 (rank : 461)
Query Neighborhood Hits	255	Target Neighborhood Hits	385	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

PACN3_MOUSE
θ value	θ > 10 (rank : 694)	NC score	0.089409 (rank : 463)
Query Neighborhood Hits	255	Target Neighborhood Hits	380	Shared Neighborhood Hits	71
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

PCNT_MOUSE
θ value	θ > 10 (rank : 695)	NC score	0.120319 (rank : 226)
Query Neighborhood Hits	255	Target Neighborhood Hits	1207	Shared Neighborhood Hits	126
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

PCQAP_HUMAN
θ value	θ > 10 (rank : 696)	NC score	0.050363 (rank : 856)
Query Neighborhood Hits	255	Target Neighborhood Hits	549	Shared Neighborhood Hits	55
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

PEX13_HUMAN
θ value	θ > 10 (rank : 697)	NC score	0.088749 (rank : 470)
Query Neighborhood Hits	255	Target Neighborhood Hits	128	Shared Neighborhood Hits	36
SwissProt Accessions	Q92968	Gene names	PEX13
Domain Architecture
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

PEX13_MOUSE
θ value	θ > 10 (rank : 698)	NC score	0.085641 (rank : 507)
Query Neighborhood Hits	255	Target Neighborhood Hits	126	Shared Neighborhood Hits	33
SwissProt Accessions	Q9D0K1, Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9EPK1	Gene names	Pex13
Domain Architecture	No domain graphic available
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

PHLB1_HUMAN
θ value	θ > 10 (rank : 699)	NC score	0.067535 (rank : 660)
Query Neighborhood Hits	255	Target Neighborhood Hits	1038	Shared Neighborhood Hits	105
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PHLB2_HUMAN
θ value	θ > 10 (rank : 700)	NC score	0.086481 (rank : 495)
Query Neighborhood Hits	255	Target Neighborhood Hits	964	Shared Neighborhood Hits	111
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PHLB2_MOUSE
θ value	θ > 10 (rank : 701)	NC score	0.087044 (rank : 489)
Query Neighborhood Hits	255	Target Neighborhood Hits	1016	Shared Neighborhood Hits	111
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PHLB3_HUMAN
θ value	θ > 10 (rank : 702)	NC score	0.057449 (rank : 775)
Query Neighborhood Hits	255	Target Neighborhood Hits	304	Shared Neighborhood Hits	60
SwissProt Accessions	Q6NSJ2, Q8N7Z4	Gene names	PHLDB3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 3.

PIBF1_HUMAN
θ value	θ > 10 (rank : 703)	NC score	0.122611 (rank : 210)
Query Neighborhood Hits	255	Target Neighborhood Hits	1041	Shared Neighborhood Hits	122
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

PININ_HUMAN
θ value	θ > 10 (rank : 704)	NC score	0.069549 (rank : 642)
Query Neighborhood Hits	255	Target Neighborhood Hits	753	Shared Neighborhood Hits	87
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

PININ_MOUSE
θ value	θ > 10 (rank : 705)	NC score	0.064853 (rank : 685)
Query Neighborhood Hits	255	Target Neighborhood Hits	777	Shared Neighborhood Hits	87
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

PKHA5_HUMAN
θ value	θ > 10 (rank : 706)	NC score	0.054901 (rank : 798)
Query Neighborhood Hits	255	Target Neighborhood Hits	455	Shared Neighborhood Hits	68
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

PKHA6_HUMAN
θ value	θ > 10 (rank : 707)	NC score	0.063639 (rank : 700)
Query Neighborhood Hits	255	Target Neighborhood Hits	556	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA6_MOUSE
θ value	θ > 10 (rank : 708)	NC score	0.064981 (rank : 679)
Query Neighborhood Hits	255	Target Neighborhood Hits	591	Shared Neighborhood Hits	56
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHF1_HUMAN
θ value	θ > 10 (rank : 709)	NC score	0.146086 (rank : 149)
Query Neighborhood Hits	255	Target Neighborhood Hits	76	Shared Neighborhood Hits	21
SwissProt Accessions	Q96S99, Q96K11, Q9BUB9	Gene names	PLEKHF1, APPD, LAPF, ZFYVE15
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (PH and FYVE domain-containing protein 1) (Phafin-1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains) (Apoptosis-inducing protein) (Zinc finger FYVE domain-containing protein 15).

PKHF1_MOUSE
θ value	θ > 10 (rank : 710)	NC score	0.144524 (rank : 151)
Query Neighborhood Hits	255	Target Neighborhood Hits	80	Shared Neighborhood Hits	20
SwissProt Accessions	Q3TB82, Q99M16	Gene names	Plekhf1, Lapf
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains).

PKHF2_HUMAN
θ value	θ > 10 (rank : 711)	NC score	0.150145 (rank : 138)
Query Neighborhood Hits	255	Target Neighborhood Hits	75	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H8W4	Gene names	PLEKHF2, ZFYVE18
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2) (PH and FYVE domain-containing protein 2) (Phafin-2) (Zinc finger FYVE domain-containing protein 18).

PKHF2_MOUSE
θ value	θ > 10 (rank : 712)	NC score	0.149545 (rank : 140)
Query Neighborhood Hits	255	Target Neighborhood Hits	77	Shared Neighborhood Hits	21
SwissProt Accessions	Q91WB4	Gene names	Plekhf2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2).

PLCB4_HUMAN
θ value	θ > 10 (rank : 713)	NC score	0.065723 (rank : 671)
Query Neighborhood Hits	255	Target Neighborhood Hits	658	Shared Neighborhood Hits	90
SwissProt Accessions	Q15147, Q5JYS8, Q5JYT0, Q5JYT4, Q9BQW5, Q9BQW6, Q9BQW8, Q9UJQ2	Gene names	PLCB4
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-4) (PLC-beta-4).

PLCG1_HUMAN
θ value	θ > 10 (rank : 714)	NC score	0.105211 (rank : 324)
Query Neighborhood Hits	255	Target Neighborhood Hits	293	Shared Neighborhood Hits	44
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLCG1_MOUSE
θ value	θ > 10 (rank : 715)	NC score	0.106276 (rank : 310)
Query Neighborhood Hits	255	Target Neighborhood Hits	314	Shared Neighborhood Hits	44
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLCG2_HUMAN
θ value	θ > 10 (rank : 716)	NC score	0.099239 (rank : 363)
Query Neighborhood Hits	255	Target Neighborhood Hits	280	Shared Neighborhood Hits	38
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

PLSI_HUMAN
θ value	θ > 10 (rank : 717)	NC score	0.063167 (rank : 711)
Query Neighborhood Hits	255	Target Neighborhood Hits	209	Shared Neighborhood Hits	34
SwissProt Accessions	Q14651	Gene names	PLS1
Domain Architecture
Description	Plastin-1 (I-plastin) (Intestine-specific plastin).

PLSL_HUMAN
θ value	θ > 10 (rank : 718)	NC score	0.059404 (rank : 756)
Query Neighborhood Hits	255	Target Neighborhood Hits	168	Shared Neighborhood Hits	34
SwissProt Accessions	P13796	Gene names	LCP1, PLS2
Domain Architecture
Description	Plastin-2 (L-plastin) (Lymphocyte cytosolic protein 1) (LCP-1) (LC64P).

PLSL_MOUSE
θ value	θ > 10 (rank : 719)	NC score	0.060435 (rank : 740)
Query Neighborhood Hits	255	Target Neighborhood Hits	170	Shared Neighborhood Hits	34
SwissProt Accessions	Q61233, Q3UE24, Q8R1X3, Q9CV77	Gene names	Lcp1, Pls2
Domain Architecture
Description	Plastin-2 (L-plastin) (Lymphocyte cytosolic protein 1) (LCP-1) (65 kDa macrophage protein) (pp65).

PLST_HUMAN
θ value	θ > 10 (rank : 720)	NC score	0.062016 (rank : 725)
Query Neighborhood Hits	255	Target Neighborhood Hits	161	Shared Neighborhood Hits	30
SwissProt Accessions	P13797, Q86YI6	Gene names	PLS3
Domain Architecture
Description	Plastin-3 (T-plastin).

PLST_MOUSE
θ value	θ > 10 (rank : 721)	NC score	0.062277 (rank : 721)
Query Neighborhood Hits	255	Target Neighborhood Hits	156	Shared Neighborhood Hits	30
SwissProt Accessions	Q99K51	Gene names	Pls3
Domain Architecture	No domain graphic available
Description	Plastin-3 (T-plastin).

PLVAP_HUMAN
θ value	θ > 10 (rank : 722)	NC score	0.064295 (rank : 688)
Query Neighborhood Hits	255	Target Neighborhood Hits	397	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BX97, Q86VP0, Q8N8Y0, Q8ND68, Q8TER8, Q9BZD5	Gene names	PLVAP, FELS, PV1
Domain Architecture	No domain graphic available
Description	Plasmalemma vesicle-associated protein (Plasmalemma vesicle protein 1) (PV-1) (Fenestrated endothelial-linked structure protein).

POF1B_HUMAN
θ value	θ > 10 (rank : 723)	NC score	0.083429 (rank : 530)
Query Neighborhood Hits	255	Target Neighborhood Hits	494	Shared Neighborhood Hits	87
SwissProt Accessions	Q8WVV4, Q5H9E9, Q5H9F0, Q8NG12, Q9H5Y2, Q9H738, Q9H744	Gene names	POF1B
Domain Architecture	No domain graphic available
Description	Protein POF1B (Premature ovarian failure protein 1B).

POF1B_MOUSE
θ value	θ > 10 (rank : 724)	NC score	0.079808 (rank : 557)
Query Neighborhood Hits	255	Target Neighborhood Hits	530	Shared Neighborhood Hits	86
SwissProt Accessions	Q8K4L4, Q8C3A2	Gene names	Pof1b
Domain Architecture	No domain graphic available
Description	Protein POF1B.

PPIP2_HUMAN
θ value	θ > 10 (rank : 725)	NC score	0.057082 (rank : 780)
Query Neighborhood Hits	255	Target Neighborhood Hits	254	Shared Neighborhood Hits	57
SwissProt Accessions	Q9H939	Gene names	PSTPIP2
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2.

PPIP2_MOUSE
θ value	θ > 10 (rank : 726)	NC score	0.054922 (rank : 797)
Query Neighborhood Hits	255	Target Neighborhood Hits	308	Shared Neighborhood Hits	58
SwissProt Accessions	Q99M15, Q9Z189	Gene names	Pstpip2, Mayp
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2 (Macrophage actin-associated tyrosine-phosphorylated protein) (pp37).

PRC1_HUMAN
θ value	θ > 10 (rank : 727)	NC score	0.057205 (rank : 778)
Query Neighborhood Hits	255	Target Neighborhood Hits	328	Shared Neighborhood Hits	69
SwissProt Accessions	O43663, Q9BSB6	Gene names	PRC1
Domain Architecture	No domain graphic available
Description	Protein regulator of cytokinesis 1.

PRC1_MOUSE
θ value	θ > 10 (rank : 728)	NC score	0.057956 (rank : 770)
Query Neighborhood Hits	255	Target Neighborhood Hits	382	Shared Neighborhood Hits	64
SwissProt Accessions	Q99K43, Q8CE25	Gene names	Prc1
Domain Architecture	No domain graphic available
Description	Protein regulator of cytokinesis 1.

RABE1_MOUSE
θ value	θ > 10 (rank : 729)	NC score	0.115905 (rank : 251)
Query Neighborhood Hits	255	Target Neighborhood Hits	1105	Shared Neighborhood Hits	120
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

RABE2_HUMAN
θ value	θ > 10 (rank : 730)	NC score	0.086433 (rank : 497)
Query Neighborhood Hits	255	Target Neighborhood Hits	545	Shared Neighborhood Hits	85
SwissProt Accessions	Q9H5N1	Gene names	RABEP2, RABPT5B
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

RABE2_MOUSE
θ value	θ > 10 (rank : 731)	NC score	0.088393 (rank : 473)
Query Neighborhood Hits	255	Target Neighborhood Hits	598	Shared Neighborhood Hits	92
SwissProt Accessions	Q91WG2, Q99KN3	Gene names	Rabep2, Rabpt5b
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

RAD50_HUMAN
θ value	θ > 10 (rank : 732)	NC score	0.129948 (rank : 175)
Query Neighborhood Hits	255	Target Neighborhood Hits	1317	Shared Neighborhood Hits	124
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

RAD50_MOUSE
θ value	θ > 10 (rank : 733)	NC score	0.128682 (rank : 184)
Query Neighborhood Hits	255	Target Neighborhood Hits	1366	Shared Neighborhood Hits	127
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

RADI_HUMAN
θ value	θ > 10 (rank : 734)	NC score	0.065613 (rank : 673)
Query Neighborhood Hits	255	Target Neighborhood Hits	741	Shared Neighborhood Hits	99
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

RADI_MOUSE
θ value	θ > 10 (rank : 735)	NC score	0.064668 (rank : 686)
Query Neighborhood Hits	255	Target Neighborhood Hits	773	Shared Neighborhood Hits	97
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

RAI14_HUMAN
θ value	θ > 10 (rank : 736)	NC score	0.073848 (rank : 603)
Query Neighborhood Hits	255	Target Neighborhood Hits	1367	Shared Neighborhood Hits	118
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

RAI14_MOUSE
θ value	θ > 10 (rank : 737)	NC score	0.078233 (rank : 565)
Query Neighborhood Hits	255	Target Neighborhood Hits	1505	Shared Neighborhood Hits	124
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

RASF8_HUMAN
θ value	θ > 10 (rank : 738)	NC score	0.070636 (rank : 631)
Query Neighborhood Hits	255	Target Neighborhood Hits	469	Shared Neighborhood Hits	77
SwissProt Accessions	Q8NHQ8, O95647, Q5SCI2, Q76KB6	Gene names	RASSF8, C12orf2
Domain Architecture
Description	Ras association domain-containing protein 8 (Carcinoma-associated protein HOJ-1).

RASF8_MOUSE
θ value	θ > 10 (rank : 739)	NC score	0.067021 (rank : 666)
Query Neighborhood Hits	255	Target Neighborhood Hits	391	Shared Neighborhood Hits	73
SwissProt Accessions	Q8CJ96, Q8CCW4, Q9CU91	Gene names	Rassf8
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 8 (Carcinoma-associated protein HOJ-1 homolog).

RBBP8_HUMAN
θ value	θ > 10 (rank : 740)	NC score	0.064122 (rank : 692)
Query Neighborhood Hits	255	Target Neighborhood Hits	476	Shared Neighborhood Hits	68
SwissProt Accessions	Q99708, O75371	Gene names	RBBP8, CTIP
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 8 (RBBP-8) (CtBP-interacting protein) (CtIP) (Retinoblastoma-interacting protein and myosin-like) (RIM).

RBCC1_HUMAN
θ value	θ > 10 (rank : 741)	NC score	0.105832 (rank : 316)
Query Neighborhood Hits	255	Target Neighborhood Hits	1023	Shared Neighborhood Hits	120
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

RBCC1_MOUSE
θ value	θ > 10 (rank : 742)	NC score	0.115181 (rank : 255)
Query Neighborhood Hits	255	Target Neighborhood Hits	1048	Shared Neighborhood Hits	122
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

RBM25_HUMAN
θ value	θ > 10 (rank : 743)	NC score	0.074272 (rank : 598)
Query Neighborhood Hits	255	Target Neighborhood Hits	682	Shared Neighborhood Hits	87
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

RBNS5_HUMAN
θ value	θ > 10 (rank : 744)	NC score	0.087835 (rank : 479)
Query Neighborhood Hits	255	Target Neighborhood Hits	242	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H1K0, Q3KP30, Q59EY8, Q8NAQ1	Gene names	ZFYVE20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20) (110 kDa protein).

RBNS5_MOUSE
θ value	θ > 10 (rank : 745)	NC score	0.088098 (rank : 477)
Query Neighborhood Hits	255	Target Neighborhood Hits	266	Shared Neighborhood Hits	47
SwissProt Accessions	Q80Y56, Q8K0L6, Q9CTW0	Gene names	Zfyve20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20).

RBP1_HUMAN
θ value	θ > 10 (rank : 746)	NC score	0.051529 (rank : 838)
Query Neighborhood Hits	255	Target Neighborhood Hits	521	Shared Neighborhood Hits	81
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

REN3B_HUMAN
θ value	θ > 10 (rank : 747)	NC score	0.063444 (rank : 704)
Query Neighborhood Hits	255	Target Neighborhood Hits	412	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BZI7, Q9H1J0	Gene names	UPF3B, RENT3B, UPF3X
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (hUpf3p-X).

RENT2_HUMAN
θ value	θ > 10 (rank : 748)	NC score	0.061875 (rank : 728)
Query Neighborhood Hits	255	Target Neighborhood Hits	618	Shared Neighborhood Hits	75
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

REST_MOUSE
θ value	θ > 10 (rank : 749)	NC score	0.127776 (rank : 187)
Query Neighborhood Hits	255	Target Neighborhood Hits	1506	Shared Neighborhood Hits	125
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

RFIP3_HUMAN
θ value	θ > 10 (rank : 750)	NC score	0.097880 (rank : 374)
Query Neighborhood Hits	255	Target Neighborhood Hits	1055	Shared Neighborhood Hits	113
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

RFIP4_HUMAN
θ value	θ > 10 (rank : 751)	NC score	0.087669 (rank : 483)
Query Neighborhood Hits	255	Target Neighborhood Hits	785	Shared Neighborhood Hits	103
SwissProt Accessions	Q86YS3, Q8N829, Q8NDT7, Q969D8	Gene names	RAB11FIP4, KIAA1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

RFIP4_MOUSE
θ value	θ > 10 (rank : 752)	NC score	0.085193 (rank : 509)
Query Neighborhood Hits	255	Target Neighborhood Hits	708	Shared Neighborhood Hits	99
SwissProt Accessions	Q8BQP8, Q80T87	Gene names	Rab11fip4, Kiaa1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

RHG04_HUMAN
θ value	θ > 10 (rank : 753)	NC score	0.089144 (rank : 465)
Query Neighborhood Hits	255	Target Neighborhood Hits	307	Shared Neighborhood Hits	54
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

RHG26_HUMAN
θ value	θ > 10 (rank : 754)	NC score	0.054804 (rank : 799)
Query Neighborhood Hits	255	Target Neighborhood Hits	281	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

RIMB1_HUMAN
θ value	θ > 10 (rank : 755)	NC score	0.111170 (rank : 282)
Query Neighborhood Hits	255	Target Neighborhood Hits	1479	Shared Neighborhood Hits	144
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RIMB1_MOUSE
θ value	θ > 10 (rank : 756)	NC score	0.119168 (rank : 230)
Query Neighborhood Hits	255	Target Neighborhood Hits	1376	Shared Neighborhood Hits	142
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RIMB2_HUMAN
θ value	θ > 10 (rank : 757)	NC score	0.072622 (rank : 618)
Query Neighborhood Hits	255	Target Neighborhood Hits	263	Shared Neighborhood Hits	37
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RIMB2_MOUSE
θ value	θ > 10 (rank : 758)	NC score	0.077726 (rank : 570)
Query Neighborhood Hits	255	Target Neighborhood Hits	246	Shared Neighborhood Hits	43
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RNF8_MOUSE
θ value	θ > 10 (rank : 759)	NC score	0.052332 (rank : 831)
Query Neighborhood Hits	255	Target Neighborhood Hits	618	Shared Neighborhood Hits	76
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

ROCK1_HUMAN
θ value	θ > 10 (rank : 760)	NC score	0.071244 (rank : 628)
Query Neighborhood Hits	255	Target Neighborhood Hits	2000	Shared Neighborhood Hits	132
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

ROCK1_MOUSE
θ value	θ > 10 (rank : 761)	NC score	0.076377 (rank : 578)
Query Neighborhood Hits	255	Target Neighborhood Hits	2126	Shared Neighborhood Hits	135
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

ROCK2_MOUSE
θ value	θ > 10 (rank : 762)	NC score	0.076175 (rank : 582)
Query Neighborhood Hits	255	Target Neighborhood Hits	2072	Shared Neighborhood Hits	145
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

RPGR1_HUMAN
θ value	θ > 10 (rank : 763)	NC score	0.094262 (rank : 415)
Query Neighborhood Hits	255	Target Neighborhood Hits	578	Shared Neighborhood Hits	95
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

RPGR1_MOUSE
θ value	θ > 10 (rank : 764)	NC score	0.065395 (rank : 676)
Query Neighborhood Hits	255	Target Neighborhood Hits	713	Shared Neighborhood Hits	88
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

RRBP1_HUMAN
θ value	θ > 10 (rank : 765)	NC score	0.102206 (rank : 339)
Query Neighborhood Hits	255	Target Neighborhood Hits	1306	Shared Neighborhood Hits	116
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

RRBP1_MOUSE
θ value	θ > 10 (rank : 766)	NC score	0.097080 (rank : 383)
Query Neighborhood Hits	255	Target Neighborhood Hits	1650	Shared Neighborhood Hits	124
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

RUFY1_HUMAN
θ value	θ > 10 (rank : 767)	NC score	0.129219 (rank : 182)
Query Neighborhood Hits	255	Target Neighborhood Hits	848	Shared Neighborhood Hits	119
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

RUFY1_MOUSE
θ value	θ > 10 (rank : 768)	NC score	0.126666 (rank : 192)
Query Neighborhood Hits	255	Target Neighborhood Hits	765	Shared Neighborhood Hits	118
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

RUFY2_HUMAN
θ value	θ > 10 (rank : 769)	NC score	0.137974 (rank : 160)
Query Neighborhood Hits	255	Target Neighborhood Hits	1208	Shared Neighborhood Hits	123
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

RUFY2_MOUSE
θ value	θ > 10 (rank : 770)	NC score	0.124954 (rank : 202)
Query Neighborhood Hits	255	Target Neighborhood Hits	820	Shared Neighborhood Hits	112
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

RUFY3_HUMAN
θ value	θ > 10 (rank : 771)	NC score	0.082794 (rank : 537)
Query Neighborhood Hits	255	Target Neighborhood Hits	594	Shared Neighborhood Hits	97
SwissProt Accessions	Q7L099, O94948, Q9UI00	Gene names	RUFY3, KIAA0871
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

RUFY3_MOUSE
θ value	θ > 10 (rank : 772)	NC score	0.083868 (rank : 524)
Query Neighborhood Hits	255	Target Neighborhood Hits	579	Shared Neighborhood Hits	97
SwissProt Accessions	Q9D394, Q3U348, Q3UF96, Q6PE64, Q8VD10	Gene names	Rufy3, D5Bwg0860e, Ripx
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

SAFB2_HUMAN
θ value	θ > 10 (rank : 773)	NC score	0.056035 (rank : 786)
Query Neighborhood Hits	255	Target Neighborhood Hits	720	Shared Neighborhood Hits	82
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

SAS6_HUMAN
θ value	θ > 10 (rank : 774)	NC score	0.094976 (rank : 410)
Query Neighborhood Hits	255	Target Neighborhood Hits	791	Shared Neighborhood Hits	105
SwissProt Accessions	Q6UVJ0, Q8N3K0	Gene names	SASS6, SAS6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog (HsSAS-6).

SAS6_MOUSE
θ value	θ > 10 (rank : 775)	NC score	0.101796 (rank : 343)
Query Neighborhood Hits	255	Target Neighborhood Hits	931	Shared Neighborhood Hits	110
SwissProt Accessions	Q80UK7, Q9CYT4	Gene names	Sass6, Sas6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog.

SDCG8_HUMAN
θ value	θ > 10 (rank : 776)	NC score	0.118233 (rank : 237)
Query Neighborhood Hits	255	Target Neighborhood Hits	1002	Shared Neighborhood Hits	115
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

SEC20_HUMAN
θ value	θ > 10 (rank : 777)	NC score	0.050018 (rank : 858)
Query Neighborhood Hits	255	Target Neighborhood Hits	200	Shared Neighborhood Hits	52
SwissProt Accessions	Q12981, O75622, O75623, O75624, Q6K044, Q96FG4	Gene names	BNIP1, NIP1, SEC20L, TRG8
Domain Architecture
Description	Vesicle transport protein SEC20 (BCL2/adenovirus E1B 19 kDa protein- interacting protein 1) (Transformation-related gene 8 protein) (TRG- 8).

SEC20_MOUSE
θ value	θ > 10 (rank : 778)	NC score	0.071416 (rank : 625)
Query Neighborhood Hits	255	Target Neighborhood Hits	323	Shared Neighborhood Hits	71
SwissProt Accessions	Q6QD59, Q5M9M2	Gene names	Bnip1, Sec20, Sec20l
Domain Architecture	No domain graphic available
Description	Vesicle transport protein SEC20.

SH3G1_HUMAN
θ value	θ > 10 (rank : 779)	NC score	0.123623 (rank : 207)
Query Neighborhood Hits	255	Target Neighborhood Hits	307	Shared Neighborhood Hits	70
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

SH3G1_MOUSE
θ value	θ > 10 (rank : 780)	NC score	0.118386 (rank : 236)
Query Neighborhood Hits	255	Target Neighborhood Hits	291	Shared Neighborhood Hits	63
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

SH3G2_HUMAN
θ value	θ > 10 (rank : 781)	NC score	0.117466 (rank : 243)
Query Neighborhood Hits	255	Target Neighborhood Hits	324	Shared Neighborhood Hits	63
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

SH3G2_MOUSE
θ value	θ > 10 (rank : 782)	NC score	0.112684 (rank : 270)
Query Neighborhood Hits	255	Target Neighborhood Hits	319	Shared Neighborhood Hits	63
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

SH3G3_HUMAN
θ value	θ > 10 (rank : 783)	NC score	0.115757 (rank : 252)
Query Neighborhood Hits	255	Target Neighborhood Hits	222	Shared Neighborhood Hits	49
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

SH3G3_MOUSE
θ value	θ > 10 (rank : 784)	NC score	0.117652 (rank : 240)
Query Neighborhood Hits	255	Target Neighborhood Hits	236	Shared Neighborhood Hits	48
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

SH3K1_HUMAN
θ value	θ > 10 (rank : 785)	NC score	0.183143 (rank : 102)
Query Neighborhood Hits	255	Target Neighborhood Hits	341	Shared Neighborhood Hits	62
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

SH3K1_MOUSE
θ value	θ > 10 (rank : 786)	NC score	0.173859 (rank : 110)
Query Neighborhood Hits	255	Target Neighborhood Hits	332	Shared Neighborhood Hits	62
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

SHAN1_HUMAN
θ value	θ > 10 (rank : 787)	NC score	0.072958 (rank : 615)
Query Neighborhood Hits	255	Target Neighborhood Hits	1041	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SHAN2_MOUSE
θ value	θ > 10 (rank : 788)	NC score	0.088173 (rank : 475)
Query Neighborhood Hits	255	Target Neighborhood Hits	446	Shared Neighborhood Hits	40
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

SHLB2_HUMAN
θ value	θ > 10 (rank : 789)	NC score	0.052984 (rank : 817)
Query Neighborhood Hits	255	Target Neighborhood Hits	86	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NR46, Q8WY61, Q96JH9	Gene names	SH3GLB2, KIAA1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

SHLB2_MOUSE
θ value	θ > 10 (rank : 790)	NC score	0.054369 (rank : 804)
Query Neighborhood Hits	255	Target Neighborhood Hits	88	Shared Neighborhood Hits	22
SwissProt Accessions	Q8R3V5, Q8K140, Q91ZI7	Gene names	Sh3glb2, Kiaa1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

SKIL_HUMAN
θ value	θ > 10 (rank : 791)	NC score	0.060143 (rank : 743)
Query Neighborhood Hits	255	Target Neighborhood Hits	460	Shared Neighborhood Hits	77
SwissProt Accessions	P12757, O00464, P12756, Q07501	Gene names	SKIL, SNO
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

SKIL_MOUSE
θ value	θ > 10 (rank : 792)	NC score	0.075123 (rank : 592)
Query Neighborhood Hits	255	Target Neighborhood Hits	719	Shared Neighborhood Hits	100
SwissProt Accessions	Q60665, Q60702, Q78E90, Q80VK5	Gene names	Skil, Skir, Sno
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

SKI_HUMAN
θ value	θ > 10 (rank : 793)	NC score	0.054107 (rank : 806)
Query Neighborhood Hits	255	Target Neighborhood Hits	423	Shared Neighborhood Hits	73
SwissProt Accessions	P12755, Q5SYT7	Gene names	SKI
Domain Architecture
Description	Ski oncogene (C-ski).

SKI_MOUSE
θ value	θ > 10 (rank : 794)	NC score	0.061047 (rank : 733)
Query Neighborhood Hits	255	Target Neighborhood Hits	423	Shared Neighborhood Hits	74
SwissProt Accessions	Q60698, Q8VIL5	Gene names	Ski
Domain Architecture	No domain graphic available
Description	Ski oncogene (C-ski).

SM1L2_HUMAN
θ value	θ > 10 (rank : 795)	NC score	0.107371 (rank : 303)
Query Neighborhood Hits	255	Target Neighborhood Hits	1019	Shared Neighborhood Hits	112
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

SM1L2_MOUSE
θ value	θ > 10 (rank : 796)	NC score	0.106562 (rank : 307)
Query Neighborhood Hits	255	Target Neighborhood Hits	918	Shared Neighborhood Hits	107
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

SMC1A_HUMAN
θ value	θ > 10 (rank : 797)	NC score	0.110402 (rank : 287)
Query Neighborhood Hits	255	Target Neighborhood Hits	1346	Shared Neighborhood Hits	123
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC1A_MOUSE
θ value	θ > 10 (rank : 798)	NC score	0.109685 (rank : 291)
Query Neighborhood Hits	255	Target Neighborhood Hits	1384	Shared Neighborhood Hits	121
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

SMC2_HUMAN
θ value	θ > 10 (rank : 799)	NC score	0.111457 (rank : 279)
Query Neighborhood Hits	255	Target Neighborhood Hits	1405	Shared Neighborhood Hits	117
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

SMC2_MOUSE
θ value	θ > 10 (rank : 800)	NC score	0.102169 (rank : 340)
Query Neighborhood Hits	255	Target Neighborhood Hits	1131	Shared Neighborhood Hits	112
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

SMC4_HUMAN
θ value	θ > 10 (rank : 801)	NC score	0.107535 (rank : 300)
Query Neighborhood Hits	255	Target Neighborhood Hits	937	Shared Neighborhood Hits	111
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

SMC4_MOUSE
θ value	θ > 10 (rank : 802)	NC score	0.100471 (rank : 353)
Query Neighborhood Hits	255	Target Neighborhood Hits	830	Shared Neighborhood Hits	105
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

SMOO_HUMAN
θ value	θ > 10 (rank : 803)	NC score	0.105008 (rank : 325)
Query Neighborhood Hits	255	Target Neighborhood Hits	391	Shared Neighborhood Hits	36
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

SNX18_HUMAN
θ value	θ > 10 (rank : 804)	NC score	0.061120 (rank : 730)
Query Neighborhood Hits	255	Target Neighborhood Hits	207	Shared Neighborhood Hits	31
SwissProt Accessions	Q96RF0	Gene names	SNAG1, SNX18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

SNX18_MOUSE
θ value	θ > 10 (rank : 805)	NC score	0.063031 (rank : 714)
Query Neighborhood Hits	255	Target Neighborhood Hits	198	Shared Neighborhood Hits	31
SwissProt Accessions	Q91ZR2	Gene names	Snag1, Snx18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

SNX23_HUMAN
θ value	θ > 10 (rank : 806)	NC score	0.086300 (rank : 499)
Query Neighborhood Hits	255	Target Neighborhood Hits	944	Shared Neighborhood Hits	114
SwissProt Accessions	Q96L93, Q5HYC0, Q5HYK1, Q5JWW3, Q5TFK5, Q86VL9, Q86YS5, Q8IYU0, Q9BQJ8, Q9BQM0, Q9BQM1, Q9BQM5, Q9H5U0, Q9HCI2, Q9NXN9	Gene names	C20orf23, KIAA1590, SNX23
Domain Architecture
Description	Kinesin-like motor protein C20orf23 (Sorting nexin-23).

SOS1_HUMAN
θ value	θ > 10 (rank : 807)	NC score	0.206337 (rank : 91)
Query Neighborhood Hits	255	Target Neighborhood Hits	274	Shared Neighborhood Hits	44
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

SOS1_MOUSE
θ value	θ > 10 (rank : 808)	NC score	0.194264 (rank : 93)
Query Neighborhood Hits	255	Target Neighborhood Hits	281	Shared Neighborhood Hits	48
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

SOS2_HUMAN
θ value	θ > 10 (rank : 809)	NC score	0.178879 (rank : 107)
Query Neighborhood Hits	255	Target Neighborhood Hits	193	Shared Neighborhood Hits	40
SwissProt Accessions	Q07890, Q15503	Gene names	SOS2
Domain Architecture
Description	Son of sevenless homolog 2 (SOS-2).

SPAG5_HUMAN
θ value	θ > 10 (rank : 810)	NC score	0.092876 (rank : 430)
Query Neighborhood Hits	255	Target Neighborhood Hits	625	Shared Neighborhood Hits	99
SwissProt Accessions	Q96R06, O95213, Q9BWE8, Q9NT17, Q9UFE6	Gene names	SPAG5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Astrin) (Mitotic spindle-associated protein p126) (MAP126) (Deepest).

SPAG5_MOUSE
θ value	θ > 10 (rank : 811)	NC score	0.105264 (rank : 321)
Query Neighborhood Hits	255	Target Neighborhood Hits	612	Shared Neighborhood Hits	95
SwissProt Accessions	Q7TME2, Q8CH61	Gene names	Spag5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Mastrin) (Mitotic spindle-associated protein p126) (MAP126).

SPC24_HUMAN
θ value	θ > 10 (rank : 812)	NC score	0.052466 (rank : 830)
Query Neighborhood Hits	255	Target Neighborhood Hits	324	Shared Neighborhood Hits	61
SwissProt Accessions	Q8NBT2	Gene names	SPBC24
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc24 (hSpc24).

SPC25_HUMAN
θ value	θ > 10 (rank : 813)	NC score	0.051429 (rank : 841)
Query Neighborhood Hits	255	Target Neighborhood Hits	273	Shared Neighborhood Hits	62
SwissProt Accessions	Q9HBM1	Gene names	SPBC25, SPC25
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc25 (hSpc25).

SRBS1_HUMAN
θ value	θ > 10 (rank : 814)	NC score	0.156406 (rank : 125)
Query Neighborhood Hits	255	Target Neighborhood Hits	396	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SRBS1_MOUSE
θ value	θ > 10 (rank : 815)	NC score	0.151312 (rank : 134)
Query Neighborhood Hits	255	Target Neighborhood Hits	409	Shared Neighborhood Hits	50
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SRC8_HUMAN
θ value	θ > 10 (rank : 816)	NC score	0.129511 (rank : 179)
Query Neighborhood Hits	255	Target Neighborhood Hits	269	Shared Neighborhood Hits	49
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

SRC8_MOUSE
θ value	θ > 10 (rank : 817)	NC score	0.125786 (rank : 198)
Query Neighborhood Hits	255	Target Neighborhood Hits	292	Shared Neighborhood Hits	48
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

SRGP1_HUMAN
θ value	θ > 10 (rank : 818)	NC score	0.073673 (rank : 607)
Query Neighborhood Hits	255	Target Neighborhood Hits	390	Shared Neighborhood Hits	72
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

SRGP2_HUMAN
θ value	θ > 10 (rank : 819)	NC score	0.073472 (rank : 609)
Query Neighborhood Hits	255	Target Neighborhood Hits	331	Shared Neighborhood Hits	64
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

SRGP2_MOUSE
θ value	θ > 10 (rank : 820)	NC score	0.074961 (rank : 595)
Query Neighborhood Hits	255	Target Neighborhood Hits	324	Shared Neighborhood Hits	65
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

STAC3_HUMAN
θ value	θ > 10 (rank : 821)	NC score	0.129972 (rank : 174)
Query Neighborhood Hits	255	Target Neighborhood Hits	228	Shared Neighborhood Hits	41
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_MOUSE
θ value	θ > 10 (rank : 822)	NC score	0.131503 (rank : 168)
Query Neighborhood Hits	255	Target Neighborhood Hits	232	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC_HUMAN
θ value	θ > 10 (rank : 823)	NC score	0.158382 (rank : 120)
Query Neighborhood Hits	255	Target Neighborhood Hits	276	Shared Neighborhood Hits	49
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

STAC_MOUSE
θ value	θ > 10 (rank : 824)	NC score	0.152391 (rank : 129)
Query Neighborhood Hits	255	Target Neighborhood Hits	268	Shared Neighborhood Hits	49
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

STAM1_HUMAN
θ value	θ > 10 (rank : 825)	NC score	0.131500 (rank : 169)
Query Neighborhood Hits	255	Target Neighborhood Hits	271	Shared Neighborhood Hits	48
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM1_MOUSE
θ value	θ > 10 (rank : 826)	NC score	0.130968 (rank : 172)
Query Neighborhood Hits	255	Target Neighborhood Hits	273	Shared Neighborhood Hits	49
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM2_HUMAN
θ value	θ > 10 (rank : 827)	NC score	0.121126 (rank : 222)
Query Neighborhood Hits	255	Target Neighborhood Hits	288	Shared Neighborhood Hits	52
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

STAM2_MOUSE
θ value	θ > 10 (rank : 828)	NC score	0.123229 (rank : 208)
Query Neighborhood Hits	255	Target Neighborhood Hits	285	Shared Neighborhood Hits	53
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

STIM1_HUMAN
θ value	θ > 10 (rank : 829)	NC score	0.069550 (rank : 641)
Query Neighborhood Hits	255	Target Neighborhood Hits	665	Shared Neighborhood Hits	93
SwissProt Accessions	Q13586	Gene names	STIM1, GOK
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

STIM1_MOUSE
θ value	θ > 10 (rank : 830)	NC score	0.067414 (rank : 662)
Query Neighborhood Hits	255	Target Neighborhood Hits	660	Shared Neighborhood Hits	92
SwissProt Accessions	P70302	Gene names	Stim1, Sim
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

STK10_HUMAN
θ value	θ > 10 (rank : 831)	NC score	0.054673 (rank : 801)
Query Neighborhood Hits	255	Target Neighborhood Hits	1921	Shared Neighborhood Hits	131
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

STK10_MOUSE
θ value	θ > 10 (rank : 832)	NC score	0.059604 (rank : 752)
Query Neighborhood Hits	255	Target Neighborhood Hits	2132	Shared Neighborhood Hits	133
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

STXB4_HUMAN
θ value	θ > 10 (rank : 833)	NC score	0.067885 (rank : 655)
Query Neighborhood Hits	255	Target Neighborhood Hits	616	Shared Neighborhood Hits	91
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

STXB4_MOUSE
θ value	θ > 10 (rank : 834)	NC score	0.057909 (rank : 771)
Query Neighborhood Hits	255	Target Neighborhood Hits	629	Shared Neighborhood Hits	92
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

SWP70_HUMAN
θ value	θ > 10 (rank : 835)	NC score	0.121826 (rank : 217)
Query Neighborhood Hits	255	Target Neighborhood Hits	973	Shared Neighborhood Hits	123
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SYCP1_HUMAN
θ value	θ > 10 (rank : 836)	NC score	0.108632 (rank : 296)
Query Neighborhood Hits	255	Target Neighborhood Hits	1313	Shared Neighborhood Hits	117
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

SYCP1_MOUSE
θ value	θ > 10 (rank : 837)	NC score	0.118589 (rank : 234)
Query Neighborhood Hits	255	Target Neighborhood Hits	1456	Shared Neighborhood Hits	128
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

T3JAM_HUMAN
θ value	θ > 10 (rank : 838)	NC score	0.090543 (rank : 453)
Query Neighborhood Hits	255	Target Neighborhood Hits	533	Shared Neighborhood Hits	90
SwissProt Accessions	Q9Y228, Q2YDB5, Q4VY06, Q7Z706	Gene names	TRAF3IP3, T3JAM
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

T3JAM_MOUSE
θ value	θ > 10 (rank : 839)	NC score	0.084836 (rank : 515)
Query Neighborhood Hits	255	Target Neighborhood Hits	535	Shared Neighborhood Hits	83
SwissProt Accessions	Q8C0G2, Q8BY50, Q8K1Y9	Gene names	Traf3ip3, T3jam
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

TACC1_HUMAN
θ value	θ > 10 (rank : 840)	NC score	0.068389 (rank : 652)
Query Neighborhood Hits	255	Target Neighborhood Hits	597	Shared Neighborhood Hits	92
SwissProt Accessions	O75410, Q6Y687, Q86YG7, Q8IUJ2, Q8IUJ3, Q8IUJ4, Q8IZG2, Q8NEY7, Q9UPP9	Gene names	TACC1, KIAA1103
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 1 (Taxin 1) (Gastric cancer antigen Ga55).

TACC1_MOUSE
θ value	θ > 10 (rank : 841)	NC score	0.073680 (rank : 606)
Query Neighborhood Hits	255	Target Neighborhood Hits	667	Shared Neighborhood Hits	95
SwissProt Accessions	Q6Y685, Q6Y686	Gene names	Tacc1
Domain Architecture	No domain graphic available
Description	Transforming acidic coiled-coil-containing protein 1.

TACC2_HUMAN
θ value	θ > 10 (rank : 842)	NC score	0.082713 (rank : 539)
Query Neighborhood Hits	255	Target Neighborhood Hits	856	Shared Neighborhood Hits	101
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

TACC2_MOUSE
θ value	θ > 10 (rank : 843)	NC score	0.076288 (rank : 581)
Query Neighborhood Hits	255	Target Neighborhood Hits	774	Shared Neighborhood Hits	104
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

TACC3_HUMAN
θ value	θ > 10 (rank : 844)	NC score	0.065376 (rank : 677)
Query Neighborhood Hits	255	Target Neighborhood Hits	779	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

TACC3_MOUSE
θ value	θ > 10 (rank : 845)	NC score	0.076319 (rank : 580)
Query Neighborhood Hits	255	Target Neighborhood Hits	607	Shared Neighborhood Hits	89
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

TARA_HUMAN
θ value	θ > 10 (rank : 846)	NC score	0.060296 (rank : 741)
Query Neighborhood Hits	255	Target Neighborhood Hits	1626	Shared Neighborhood Hits	105
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TARA_MOUSE
θ value	θ > 10 (rank : 847)	NC score	0.063832 (rank : 698)
Query Neighborhood Hits	255	Target Neighborhood Hits	1133	Shared Neighborhood Hits	102
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TAXB1_HUMAN
θ value	θ > 10 (rank : 848)	NC score	0.102909 (rank : 336)
Query Neighborhood Hits	255	Target Neighborhood Hits	829	Shared Neighborhood Hits	93
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

TCGAP_HUMAN
θ value	θ > 10 (rank : 849)	NC score	0.066629 (rank : 668)
Query Neighborhood Hits	255	Target Neighborhood Hits	872	Shared Neighborhood Hits	49
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TCGAP_MOUSE
θ value	θ > 10 (rank : 850)	NC score	0.073763 (rank : 605)
Query Neighborhood Hits	255	Target Neighborhood Hits	409	Shared Neighborhood Hits	44
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TCRG1_HUMAN
θ value	θ > 10 (rank : 851)	NC score	0.065515 (rank : 675)
Query Neighborhood Hits	255	Target Neighborhood Hits	929	Shared Neighborhood Hits	91
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
θ value	θ > 10 (rank : 852)	NC score	0.065646 (rank : 672)
Query Neighborhood Hits	255	Target Neighborhood Hits	947	Shared Neighborhood Hits	91
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TEKT1_HUMAN
θ value	θ > 10 (rank : 853)	NC score	0.062964 (rank : 715)
Query Neighborhood Hits	255	Target Neighborhood Hits	289	Shared Neighborhood Hits	68
SwissProt Accessions	Q969V4	Gene names	TEKT1
Domain Architecture
Description	Tektin-1.

TEKT1_MOUSE
θ value	θ > 10 (rank : 854)	NC score	0.074948 (rank : 596)
Query Neighborhood Hits	255	Target Neighborhood Hits	399	Shared Neighborhood Hits	79
SwissProt Accessions	Q9DAJ2	Gene names	Tekt1
Domain Architecture
Description	Tektin-1.

TEX9_HUMAN
θ value	θ > 10 (rank : 855)	NC score	0.083398 (rank : 531)
Query Neighborhood Hits	255	Target Neighborhood Hits	541	Shared Neighborhood Hits	89
SwissProt Accessions	Q8N6V9	Gene names	TEX9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein.

TEX9_MOUSE
θ value	θ > 10 (rank : 856)	NC score	0.094097 (rank : 418)
Query Neighborhood Hits	255	Target Neighborhood Hits	581	Shared Neighborhood Hits	92
SwissProt Accessions	Q9D845, O54764	Gene names	Tex9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein (Testis-specifically expressed protein 1) (Tsec-1).

TMF1_HUMAN
θ value	θ > 10 (rank : 857)	NC score	0.117522 (rank : 241)
Query Neighborhood Hits	255	Target Neighborhood Hits	987	Shared Neighborhood Hits	111
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

TNIP3_HUMAN
θ value	θ > 10 (rank : 858)	NC score	0.084890 (rank : 514)
Query Neighborhood Hits	255	Target Neighborhood Hits	511	Shared Neighborhood Hits	82
SwissProt Accessions	Q96KP6, Q96PQ3, Q9H780	Gene names	TNIP3, ABIN3, LIND
Domain Architecture	No domain graphic available
Description	TNFAIP3-interacting protein 3 (Listeria-induced gene protein) (A20- binding inhibitor of NF-kappa-B activation 3) (ABIN-3).

TNNT2_HUMAN
θ value	θ > 10 (rank : 859)	NC score	0.050235 (rank : 857)
Query Neighborhood Hits	255	Target Neighborhood Hits	433	Shared Neighborhood Hits	68
SwissProt Accessions	P45379, O60214, Q99596, Q99597, Q9UM96	Gene names	TNNT2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

TNNT3_HUMAN
θ value	θ > 10 (rank : 860)	NC score	0.053959 (rank : 807)
Query Neighborhood Hits	255	Target Neighborhood Hits	327	Shared Neighborhood Hits	63
SwissProt Accessions	P45378, Q12975, Q12976, Q12977, Q12978, Q86TH6	Gene names	TNNT3
Domain Architecture	No domain graphic available
Description	Troponin T, fast skeletal muscle (TnTf) (Fast skeletal muscle troponin T) (fTnT) (Beta TnTF).

TNNT3_MOUSE
θ value	θ > 10 (rank : 861)	NC score	0.053944 (rank : 808)
Query Neighborhood Hits	255	Target Neighborhood Hits	317	Shared Neighborhood Hits	64
SwissProt Accessions	Q9QZ47, O35575, O35576, O35577, O35578, O35579, O35580, O35581, O35582, O35583, O35584, O35585, P97456, Q99L89, Q9QZ46	Gene names	Tnnt3
Domain Architecture	No domain graphic available
Description	Troponin T, fast skeletal muscle (TnTf) (Fast skeletal muscle troponin T) (fTnT).

TPM1_HUMAN
θ value	θ > 10 (rank : 862)	NC score	0.088822 (rank : 468)
Query Neighborhood Hits	255	Target Neighborhood Hits	716	Shared Neighborhood Hits	102
SwissProt Accessions	P09493, P09494, P10469, Q86W64, Q96IK2, Q9UCY9	Gene names	TPM1, TMSA
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

TPM1_MOUSE
θ value	θ > 10 (rank : 863)	NC score	0.087778 (rank : 480)
Query Neighborhood Hits	255	Target Neighborhood Hits	729	Shared Neighborhood Hits	102
SwissProt Accessions	P58771, P02558, P19354, P46902, P99034	Gene names	Tpm1, Tpm-1, Tpma
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

TPM2_HUMAN
θ value	θ > 10 (rank : 864)	NC score	0.093405 (rank : 424)
Query Neighborhood Hits	255	Target Neighborhood Hits	677	Shared Neighborhood Hits	101
SwissProt Accessions	P07951, P06468, Q13894, Q53FM4, Q5TCU4, Q5TCU7, Q9UH67	Gene names	TPM2, TMSB
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

TPM2_MOUSE
θ value	θ > 10 (rank : 865)	NC score	0.091266 (rank : 446)
Query Neighborhood Hits	255	Target Neighborhood Hits	676	Shared Neighborhood Hits	100
SwissProt Accessions	P58774, P02560, P46901	Gene names	Tpm2, Tpm-2
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

TPM3_HUMAN
θ value	θ > 10 (rank : 866)	NC score	0.092386 (rank : 433)
Query Neighborhood Hits	255	Target Neighborhood Hits	689	Shared Neighborhood Hits	102
SwissProt Accessions	P06753, P12324, Q969Q2, Q9NQH8	Gene names	TPM3
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma) (hTM5).

TPM3_MOUSE
θ value	θ > 10 (rank : 867)	NC score	0.092117 (rank : 435)
Query Neighborhood Hits	255	Target Neighborhood Hits	676	Shared Neighborhood Hits	100
SwissProt Accessions	P21107, Q09021, Q60606, Q80SW6, Q9EPW3	Gene names	Tpm3, Tpm-5, Tpm5
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma).

TPM4_HUMAN
θ value	θ > 10 (rank : 868)	NC score	0.081287 (rank : 544)
Query Neighborhood Hits	255	Target Neighborhood Hits	525	Shared Neighborhood Hits	85
SwissProt Accessions	P67936, P07226, Q15659, Q9BU85, Q9H8Q3	Gene names	TPM4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4) (TM30p1).

TPM4_MOUSE
θ value	θ > 10 (rank : 869)	NC score	0.081612 (rank : 543)
Query Neighborhood Hits	255	Target Neighborhood Hits	703	Shared Neighborhood Hits	96
SwissProt Accessions	Q6IRU2	Gene names	Tpm4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4).

TPR_HUMAN
θ value	θ > 10 (rank : 870)	NC score	0.121158 (rank : 220)
Query Neighborhood Hits	255	Target Neighborhood Hits	1921	Shared Neighborhood Hits	140
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

TRAIP_HUMAN
θ value	θ > 10 (rank : 871)	NC score	0.083110 (rank : 536)
Query Neighborhood Hits	255	Target Neighborhood Hits	780	Shared Neighborhood Hits	94
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TRAIP_MOUSE
θ value	θ > 10 (rank : 872)	NC score	0.080849 (rank : 548)
Query Neighborhood Hits	255	Target Neighborhood Hits	745	Shared Neighborhood Hits	93
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

TRAK1_HUMAN
θ value	θ > 10 (rank : 873)	NC score	0.092326 (rank : 434)
Query Neighborhood Hits	255	Target Neighborhood Hits	660	Shared Neighborhood Hits	102
SwissProt Accessions	Q9UPV9, Q96B69	Gene names	TRAK1, KIAA1042, OIP106
Domain Architecture	No domain graphic available
Description	Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase- interacting protein).

TRAK2_HUMAN
θ value	θ > 10 (rank : 874)	NC score	0.066517 (rank : 670)
Query Neighborhood Hits	255	Target Neighborhood Hits	476	Shared Neighborhood Hits	80
SwissProt Accessions	O60296, Q8WVH7, Q96NS2, Q9C0K5, Q9C0K6	Gene names	TRAK2, ALS2CR3, KIAA0549
Domain Architecture
Description	Trafficking kinesin-binding protein 2 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein).

TRDN_HUMAN
θ value	θ > 10 (rank : 875)	NC score	0.052660 (rank : 825)
Query Neighborhood Hits	255	Target Neighborhood Hits	542	Shared Neighborhood Hits	61
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

TRHY_HUMAN
θ value	θ > 10 (rank : 876)	NC score	0.114485 (rank : 257)
Query Neighborhood Hits	255	Target Neighborhood Hits	1385	Shared Neighborhood Hits	117
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

TSC1_HUMAN
θ value	θ > 10 (rank : 877)	NC score	0.092572 (rank : 431)
Query Neighborhood Hits	255	Target Neighborhood Hits	765	Shared Neighborhood Hits	95
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

TTC3_HUMAN
θ value	θ > 10 (rank : 878)	NC score	0.067629 (rank : 657)
Query Neighborhood Hits	255	Target Neighborhood Hits	664	Shared Neighborhood Hits	84
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

TUFT1_MOUSE
θ value	θ > 10 (rank : 879)	NC score	0.097860 (rank : 375)
Query Neighborhood Hits	255	Target Neighborhood Hits	732	Shared Neighborhood Hits	103
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

TXLNA_HUMAN
θ value	θ > 10 (rank : 880)	NC score	0.080513 (rank : 550)
Query Neighborhood Hits	255	Target Neighborhood Hits	982	Shared Neighborhood Hits	101
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

TXLNA_MOUSE
θ value	θ > 10 (rank : 881)	NC score	0.087031 (rank : 490)
Query Neighborhood Hits	255	Target Neighborhood Hits	846	Shared Neighborhood Hits	107
SwissProt Accessions	Q6PAM1, Q6P1E5	Gene names	Txlna, Txln
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

TXLNB_MOUSE
θ value	θ > 10 (rank : 882)	NC score	0.083117 (rank : 535)
Query Neighborhood Hits	255	Target Neighborhood Hits	640	Shared Neighborhood Hits	93
SwissProt Accessions	Q8VBT1, Q3UVB8, Q8BUK2	Gene names	Txlnb, Mdp77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77).

TXLNG_HUMAN
θ value	θ > 10 (rank : 883)	NC score	0.077352 (rank : 572)
Query Neighborhood Hits	255	Target Neighborhood Hits	568	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NUQ3, Q9P0X1	Gene names	TXLNG, CXorf15, LSR5
Domain Architecture	No domain graphic available
Description	Gamma-taxilin (Lipopolysaccharide-specific response protein 5).

TXLNG_MOUSE
θ value	θ > 10 (rank : 884)	NC score	0.085112 (rank : 511)
Query Neighborhood Hits	255	Target Neighborhood Hits	552	Shared Neighborhood Hits	90
SwissProt Accessions	Q8BHN1, Q8BP11	Gene names	Txlng
Domain Architecture	No domain graphic available
Description	Gamma-taxilin.

U2AFM_HUMAN
θ value	θ > 10 (rank : 885)	NC score	0.054562 (rank : 802)
Query Neighborhood Hits	255	Target Neighborhood Hits	577	Shared Neighborhood Hits	76
SwissProt Accessions	Q15696	Gene names	ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (NY-REN-20 antigen).

U2AFM_MOUSE
θ value	θ > 10 (rank : 886)	NC score	0.052939 (rank : 818)
Query Neighborhood Hits	255	Target Neighborhood Hits	543	Shared Neighborhood Hits	74
SwissProt Accessions	Q62377	Gene names	Zrsr2, U2af1-rs2, U2af1l2, U2af1rs2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2).

UACA_HUMAN
θ value	θ > 10 (rank : 887)	NC score	0.096265 (rank : 394)
Query Neighborhood Hits	255	Target Neighborhood Hits	1622	Shared Neighborhood Hits	127
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

UACA_MOUSE
θ value	θ > 10 (rank : 888)	NC score	0.095209 (rank : 409)
Query Neighborhood Hits	255	Target Neighborhood Hits	1620	Shared Neighborhood Hits	132
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

UTRO_HUMAN
θ value	θ > 10 (rank : 889)	NC score	0.182190 (rank : 104)
Query Neighborhood Hits	255	Target Neighborhood Hits	960	Shared Neighborhood Hits	120
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

VDP_HUMAN
θ value	θ > 10 (rank : 890)	NC score	0.084451 (rank : 517)
Query Neighborhood Hits	255	Target Neighborhood Hits	645	Shared Neighborhood Hits	93
SwissProt Accessions	O60763	Gene names	VDP
Domain Architecture
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

VDP_MOUSE
θ value	θ > 10 (rank : 891)	NC score	0.066701 (rank : 667)
Query Neighborhood Hits	255	Target Neighborhood Hits	469	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Z1Z0, Q3T9L9, Q3TH58, Q3U1C7, Q3UMW6, Q91WE7, Q99JZ5	Gene names	Vdp
Domain Architecture	No domain graphic available
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

VINEX_HUMAN
θ value	θ > 10 (rank : 892)	NC score	0.151090 (rank : 137)
Query Neighborhood Hits	255	Target Neighborhood Hits	270	Shared Neighborhood Hits	52
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

VINEX_MOUSE
θ value	θ > 10 (rank : 893)	NC score	0.151327 (rank : 133)
Query Neighborhood Hits	255	Target Neighborhood Hits	286	Shared Neighborhood Hits	50
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

WDFY1_HUMAN
θ value	θ > 10 (rank : 894)	NC score	0.051215 (rank : 845)
Query Neighborhood Hits	255	Target Neighborhood Hits	305	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IWB7, Q9H9D5, Q9P2B3	Gene names	WDFY1, KIAA1435, WDF1, ZFYVE17
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 1 (WD40- and FYVE domain- containing protein 1) (Phosphoinositide-binding protein 1) (FENS-1) (Zinc finger FYVE domain-containing protein 17).

WDFY3_HUMAN
θ value	θ > 10 (rank : 895)	NC score	0.052827 (rank : 821)
Query Neighborhood Hits	255	Target Neighborhood Hits	348	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IZQ1, Q4W5K5, Q6P0Q5, Q8N1T2, Q96BS7, Q96N85, Q9Y2J7	Gene names	WDFY3, KIAA0993
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy).

WDFY3_MOUSE
θ value	θ > 10 (rank : 896)	NC score	0.052625 (rank : 827)
Query Neighborhood Hits	255	Target Neighborhood Hits	332	Shared Neighborhood Hits	22
SwissProt Accessions	Q6VNB8, Q8C8H7	Gene names	Wdfy3
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Beach domain, WD repeat and FYVE domain-containing protein 1) (BWF1).

WDR67_HUMAN
θ value	θ > 10 (rank : 897)	NC score	0.080051 (rank : 553)
Query Neighborhood Hits	255	Target Neighborhood Hits	782	Shared Neighborhood Hits	94
SwissProt Accessions	Q96DN5, Q3MIR6, Q8TBP9	Gene names	WDR67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67.

XE7_HUMAN
θ value	θ > 10 (rank : 898)	NC score	0.091064 (rank : 449)
Query Neighborhood Hits	255	Target Neighborhood Hits	738	Shared Neighborhood Hits	95
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

YES_HUMAN
θ value	θ > 10 (rank : 899)	NC score	0.051225 (rank : 844)
Query Neighborhood Hits	255	Target Neighborhood Hits	1059	Shared Neighborhood Hits	56
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

YES_MOUSE
θ value	θ > 10 (rank : 900)	NC score	0.051491 (rank : 840)
Query Neighborhood Hits	255	Target Neighborhood Hits	1052	Shared Neighborhood Hits	56
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

YO11_MOUSE
θ value	θ > 10 (rank : 901)	NC score	0.057678 (rank : 773)
Query Neighborhood Hits	255	Target Neighborhood Hits	272	Shared Neighborhood Hits	56
SwissProt Accessions	P11260	Gene names
Domain Architecture
Description	Hypothetical protein ORF-1137.

ZC313_HUMAN
θ value	θ > 10 (rank : 902)	NC score	0.055269 (rank : 792)
Query Neighborhood Hits	255	Target Neighborhood Hits	772	Shared Neighborhood Hits	64
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

ZFY16_HUMAN
θ value	θ > 10 (rank : 903)	NC score	0.091079 (rank : 448)
Query Neighborhood Hits	255	Target Neighborhood Hits	125	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z3T8, O15023, Q7LAU7, Q86T69, Q8N5L3, Q8NEK3	Gene names	ZFYVE16, KIAA0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome- associated FYVE domain protein).

ZFY16_MOUSE
θ value	θ > 10 (rank : 904)	NC score	0.093331 (rank : 426)
Query Neighborhood Hits	255	Target Neighborhood Hits	108	Shared Neighborhood Hits	16
SwissProt Accessions	Q80U44, Q8BRD2, Q8CG97	Gene names	Zfyve16, Kiaa0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosomal- associated FYVE domain protein).

ZFY19_HUMAN
θ value	θ > 10 (rank : 905)	NC score	0.070349 (rank : 635)
Query Neighborhood Hits	255	Target Neighborhood Hits	206	Shared Neighborhood Hits	27
SwissProt Accessions	Q96K21, Q86WC2, Q8WU96	Gene names	ZFYVE19, MPFYVE
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19 (MLL partner containing FYVE domain).

ZFY19_MOUSE
θ value	θ > 10 (rank : 906)	NC score	0.064014 (rank : 693)
Query Neighborhood Hits	255	Target Neighborhood Hits	143	Shared Neighborhood Hits	22
SwissProt Accessions	Q9DAZ9, Q8VCV7	Gene names	Zfyve19
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19.

ZFY21_HUMAN
θ value	θ > 10 (rank : 907)	NC score	0.089985 (rank : 460)
Query Neighborhood Hits	255	Target Neighborhood Hits	72	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BQ24, Q86T05, Q96LT1	Gene names	ZFYVE21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

ZFY21_MOUSE
θ value	θ > 10 (rank : 908)	NC score	0.091852 (rank : 441)
Query Neighborhood Hits	255	Target Neighborhood Hits	72	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VCM3, Q9D1E2	Gene names	Zfyve21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

ZFY28_HUMAN
θ value	θ > 10 (rank : 909)	NC score	0.100487 (rank : 352)
Query Neighborhood Hits	255	Target Neighborhood Hits	152	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HCC9	Gene names	ZFYVE28, KIAA1643
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 28.

ZFYV1_HUMAN
θ value	θ > 10 (rank : 910)	NC score	0.061990 (rank : 726)
Query Neighborhood Hits	255	Target Neighborhood Hits	166	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HBF4, Q8WYX7, Q96K57, Q9BXP9, Q9HCI3	Gene names	ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (Tandem FYVE fingers-1) (SR3).

ZFYV1_MOUSE
θ value	θ > 10 (rank : 911)	NC score	0.059882 (rank : 749)
Query Neighborhood Hits	255	Target Neighborhood Hits	153	Shared Neighborhood Hits	15
SwissProt Accessions	Q810J8	Gene names	Zfyve1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1.

ZFYV9_HUMAN
θ value	θ > 10 (rank : 912)	NC score	0.098156 (rank : 370)
Query Neighborhood Hits	255	Target Neighborhood Hits	134	Shared Neighborhood Hits	17
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

ZRF1_MOUSE
θ value	θ > 10 (rank : 913)	NC score	0.051744 (rank : 836)
Query Neighborhood Hits	255	Target Neighborhood Hits	414	Shared Neighborhood Hits	63
SwissProt Accessions	P54103	Gene names	Zrf1, Dnajc2
Domain Architecture
Description	Zuotin-related factor 1.

ZWINT_HUMAN
θ value	θ > 10 (rank : 914)	NC score	0.063202 (rank : 710)
Query Neighborhood Hits	255	Target Neighborhood Hits	333	Shared Neighborhood Hits	61
SwissProt Accessions	O95229, Q9BWD0	Gene names	ZWINT
Domain Architecture	No domain graphic available
Description	ZW10 interactor (ZW10-interacting protein 1) (Zwint-1).

ZWINT_MOUSE
θ value	θ > 10 (rank : 915)	NC score	0.088296 (rank : 474)
Query Neighborhood Hits	255	Target Neighborhood Hits	497	Shared Neighborhood Hits	85
SwissProt Accessions	Q9CQU5, Q3UYT8, Q91VI4, Q9D0W9	Gene names	Zwint, D10Ertd749e
Domain Architecture	No domain graphic available
Description	ZW10 interactor (ZW10-interacting protein 1) (Zwint-1).

Hits sorted by NC score

MCF2L_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	255	Target Neighborhood Hits	255	Shared Neighborhood Hits	255
SwissProt Accessions	Q64096	Gene names	Mcf2l, Dbs
Domain Architecture
Description	Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2- transforming sequence-like protein).

MCF2_HUMAN
NC score	0.925254 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	255	Target Neighborhood Hits	166	Shared Neighborhood Hits	101
SwissProt Accessions	P10911, P14919, Q5JYJ4, Q8IUF3, Q8IUF4, Q9UJB3	Gene names	MCF2, DBL
Domain Architecture
Description	Proto-oncogene DBL (Proto-oncogene MCF-2) [Contains: MCF2-transforming protein; DBL-transforming protein].

HAPIP_HUMAN
NC score	0.784259 (rank : 3)	θ value	3.48141e-52 (rank : 3)
Query Neighborhood Hits	255	Target Neighborhood Hits	350	Shared Neighborhood Hits	133
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

PKHG1_HUMAN
NC score	0.780043 (rank : 4)	θ value	1.37539e-32 (rank : 7)
Query Neighborhood Hits	255	Target Neighborhood Hits	174	Shared Neighborhood Hits	72
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

PKHG4_HUMAN
NC score	0.762293 (rank : 5)	θ value	3.73686e-38 (rank : 6)
Query Neighborhood Hits	255	Target Neighborhood Hits	200	Shared Neighborhood Hits	62
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

ARHG4_MOUSE
NC score	0.713800 (rank : 6)	θ value	4.15078e-21 (rank : 10)
Query Neighborhood Hits	255	Target Neighborhood Hits	185	Shared Neighborhood Hits	81
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG4_HUMAN
NC score	0.695783 (rank : 7)	θ value	1.6852e-22 (rank : 9)
Query Neighborhood Hits	255	Target Neighborhood Hits	242	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG9_HUMAN
NC score	0.691921 (rank : 8)	θ value	8.95645e-16 (rank : 12)
Query Neighborhood Hits	255	Target Neighborhood Hits	235	Shared Neighborhood Hits	91
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

ARHG9_MOUSE
NC score	0.691869 (rank : 9)	θ value	8.95645e-16 (rank : 13)
Query Neighborhood Hits	255	Target Neighborhood Hits	234	Shared Neighborhood Hits	91
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

PREX1_HUMAN
NC score	0.680316 (rank : 10)	θ value	7.32683e-18 (rank : 11)
Query Neighborhood Hits	255	Target Neighborhood Hits	177	Shared Neighborhood Hits	71
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

TIAM1_MOUSE
NC score	0.650670 (rank : 11)	θ value	2.43908e-13 (rank : 19)
Query Neighborhood Hits	255	Target Neighborhood Hits	205	Shared Neighborhood Hits	75
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TIAM1_HUMAN
NC score	0.644180 (rank : 12)	θ value	8.38298e-14 (rank : 16)
Query Neighborhood Hits	255	Target Neighborhood Hits	225	Shared Neighborhood Hits	77
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

FGD3_MOUSE
NC score	0.603387 (rank : 13)	θ value	1.33837e-11 (rank : 23)
Query Neighborhood Hits	255	Target Neighborhood Hits	257	Shared Neighborhood Hits	72
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

FGD3_HUMAN
NC score	0.578579 (rank : 14)	θ value	4.59992e-12 (rank : 21)
Query Neighborhood Hits	255	Target Neighborhood Hits	249	Shared Neighborhood Hits	70
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

FGD2_HUMAN
NC score	0.571470 (rank : 15)	θ value	5.43371e-13 (rank : 20)
Query Neighborhood Hits	255	Target Neighborhood Hits	151	Shared Neighborhood Hits	74
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

FGD2_MOUSE
NC score	0.568566 (rank : 16)	θ value	2.98157e-11 (rank : 25)
Query Neighborhood Hits	255	Target Neighborhood Hits	163	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

ARHG8_HUMAN
NC score	0.563263 (rank : 17)	θ value	8.97725e-08 (rank : 39)
Query Neighborhood Hits	255	Target Neighborhood Hits	85	Shared Neighborhood Hits	68
SwissProt Accessions	Q7Z628, Q12773, Q96D82, Q99903, Q9UEN6	Gene names	NET1, ARHGEF8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (p65 Net1 proto- oncogene) (Rho guanine nucleotide exchange factor 8).

ARHG3_HUMAN
NC score	0.562683 (rank : 18)	θ value	7.59969e-07 (rank : 49)
Query Neighborhood Hits	255	Target Neighborhood Hits	82	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

ARHG3_MOUSE
NC score	0.560406 (rank : 19)	θ value	7.59969e-07 (rank : 50)
Query Neighborhood Hits	255	Target Neighborhood Hits	85	Shared Neighborhood Hits	66
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

FGD4_HUMAN
NC score	0.557293 (rank : 20)	θ value	2.61198e-07 (rank : 43)
Query Neighborhood Hits	255	Target Neighborhood Hits	219	Shared Neighborhood Hits	81
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

FGD4_MOUSE
NC score	0.556702 (rank : 21)	θ value	5.26297e-08 (rank : 35)
Query Neighborhood Hits	255	Target Neighborhood Hits	227	Shared Neighborhood Hits	76
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

ARHG7_HUMAN
NC score	0.552176 (rank : 22)	θ value	5.08577e-11 (rank : 26)
Query Neighborhood Hits	255	Target Neighborhood Hits	347	Shared Neighborhood Hits	104
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

ARHG7_MOUSE
NC score	0.550704 (rank : 23)	θ value	9.59137e-10 (rank : 28)
Query Neighborhood Hits	255	Target Neighborhood Hits	396	Shared Neighborhood Hits	114
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

ARHG8_MOUSE
NC score	0.545090 (rank : 24)	θ value	1.17247e-07 (rank : 40)
Query Neighborhood Hits	255	Target Neighborhood Hits	79	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Z206, Q8C4I0, Q9Z1L7	Gene names	Net1, Arhgef8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (Rho guanine nucleotide exchange factor 8).

ARHGA_HUMAN
NC score	0.532218 (rank : 25)	θ value	6.87365e-08 (rank : 37)
Query Neighborhood Hits	255	Target Neighborhood Hits	187	Shared Neighborhood Hits	78
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ARHGA_MOUSE
NC score	0.529993 (rank : 26)	θ value	2.61198e-07 (rank : 42)
Query Neighborhood Hits	255	Target Neighborhood Hits	125	Shared Neighborhood Hits	70
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

FGD1_HUMAN
NC score	0.529783 (rank : 27)	θ value	8.11959e-09 (rank : 30)
Query Neighborhood Hits	255	Target Neighborhood Hits	367	Shared Neighborhood Hits	79
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD1_MOUSE
NC score	0.528938 (rank : 28)	θ value	1.06045e-08 (rank : 31)
Query Neighborhood Hits	255	Target Neighborhood Hits	387	Shared Neighborhood Hits	78
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

ECT2_MOUSE
NC score	0.528228 (rank : 29)	θ value	0.0563607 (rank : 105)
Query Neighborhood Hits	255	Target Neighborhood Hits	98	Shared Neighborhood Hits	71
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

VAV_MOUSE
NC score	0.527581 (rank : 30)	θ value	4.44505e-15 (rank : 15)
Query Neighborhood Hits	255	Target Neighborhood Hits	430	Shared Neighborhood Hits	106
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

ARHG6_HUMAN
NC score	0.525845 (rank : 31)	θ value	1.80886e-08 (rank : 32)
Query Neighborhood Hits	255	Target Neighborhood Hits	376	Shared Neighborhood Hits	107
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

DNMBP_MOUSE
NC score	0.522153 (rank : 32)	θ value	1.25267e-09 (rank : 29)
Query Neighborhood Hits	255	Target Neighborhood Hits	435	Shared Neighborhood Hits	98
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

DNMBP_HUMAN
NC score	0.519532 (rank : 33)	θ value	5.26297e-08 (rank : 34)
Query Neighborhood Hits	255	Target Neighborhood Hits	413	Shared Neighborhood Hits	112
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

VAV_HUMAN
NC score	0.518553 (rank : 34)	θ value	1.99529e-15 (rank : 14)
Query Neighborhood Hits	255	Target Neighborhood Hits	452	Shared Neighborhood Hits	103
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

ECT2_HUMAN
NC score	0.512861 (rank : 35)	θ value	0.21417 (rank : 127)
Query Neighborhood Hits	255	Target Neighborhood Hits	98	Shared Neighborhood Hits	71
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

VAV2_MOUSE
NC score	0.509097 (rank : 36)	θ value	1.09485e-13 (rank : 17)
Query Neighborhood Hits	255	Target Neighborhood Hits	456	Shared Neighborhood Hits	106
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

VAV2_HUMAN
NC score	0.507227 (rank : 37)	θ value	1.86753e-13 (rank : 18)
Query Neighborhood Hits	255	Target Neighborhood Hits	453	Shared Neighborhood Hits	105
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

ARHG6_MOUSE
NC score	0.506842 (rank : 38)	θ value	3.08544e-08 (rank : 33)
Query Neighborhood Hits	255	Target Neighborhood Hits	394	Shared Neighborhood Hits	108
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

VAV3_HUMAN
NC score	0.500207 (rank : 39)	θ value	7.84624e-12 (rank : 22)
Query Neighborhood Hits	255	Target Neighborhood Hits	398	Shared Neighborhood Hits	97
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

VAV3_MOUSE
NC score	0.497226 (rank : 40)	θ value	5.08577e-11 (rank : 27)
Query Neighborhood Hits	255	Target Neighborhood Hits	404	Shared Neighborhood Hits	98
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

ARHGG_HUMAN
NC score	0.491509 (rank : 41)	θ value	0.000602161 (rank : 64)
Query Neighborhood Hits	255	Target Neighborhood Hits	129	Shared Neighborhood Hits	68
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

FGD6_MOUSE
NC score	0.481788 (rank : 42)	θ value	5.26297e-08 (rank : 36)
Query Neighborhood Hits	255	Target Neighborhood Hits	282	Shared Neighborhood Hits	77
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

ARHGG_MOUSE
NC score	0.480615 (rank : 43)	θ value	0.000786445 (rank : 65)
Query Neighborhood Hits	255	Target Neighborhood Hits	152	Shared Neighborhood Hits	75
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

FGD6_HUMAN
NC score	0.479864 (rank : 44)	θ value	6.87365e-08 (rank : 38)
Query Neighborhood Hits	255	Target Neighborhood Hits	237	Shared Neighborhood Hits	72
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

ARHG5_HUMAN
NC score	0.476466 (rank : 45)	θ value	0.0563607 (rank : 104)
Query Neighborhood Hits	255	Target Neighborhood Hits	172	Shared Neighborhood Hits	80
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

NGEF_HUMAN
NC score	0.472077 (rank : 46)	θ value	0.000461057 (rank : 63)
Query Neighborhood Hits	255	Target Neighborhood Hits	166	Shared Neighborhood Hits	75
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

NGEF_MOUSE
NC score	0.467313 (rank : 47)	θ value	0.00035302 (rank : 59)
Query Neighborhood Hits	255	Target Neighborhood Hits	228	Shared Neighborhood Hits	75
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

ARHG1_HUMAN
NC score	0.440452 (rank : 48)	θ value	0.00665767 (rank : 79)
Query Neighborhood Hits	255	Target Neighborhood Hits	176	Shared Neighborhood Hits	68
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

ITSN2_HUMAN
NC score	0.436879 (rank : 49)	θ value	4.45536e-07 (rank : 46)
Query Neighborhood Hits	255	Target Neighborhood Hits	1173	Shared Neighborhood Hits	184
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

ARHGB_HUMAN
NC score	0.427978 (rank : 50)	θ value	0.00665767 (rank : 80)
Query Neighborhood Hits	255	Target Neighborhood Hits	375	Shared Neighborhood Hits	82
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

ARHGC_HUMAN
NC score	0.420510 (rank : 51)	θ value	0.00134147 (rank : 71)
Query Neighborhood Hits	255	Target Neighborhood Hits	351	Shared Neighborhood Hits	83
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ITSN2_MOUSE
NC score	0.420114 (rank : 52)	θ value	1.99992e-07 (rank : 41)
Query Neighborhood Hits	255	Target Neighborhood Hits	1371	Shared Neighborhood Hits	188
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

ARHG2_MOUSE
NC score	0.418452 (rank : 53)	θ value	0.0563607 (rank : 103)
Query Neighborhood Hits	255	Target Neighborhood Hits	120	Shared Neighborhood Hits	68
SwissProt Accessions	Q60875, O09115	Gene names	Arhgef2, Lbcl1, Lfc
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (Lymphoid blast crisis- like 1) (LBC'S first cousin) (Oncogene LFC) (RHOBIN).

LBC_HUMAN
NC score	0.417837 (rank : 54)	θ value	0.000461057 (rank : 62)
Query Neighborhood Hits	255	Target Neighborhood Hits	90	Shared Neighborhood Hits	63
SwissProt Accessions	Q12802	Gene names	LBC
Domain Architecture
Description	LBC oncogene (P47) (Lymphoid blast crisis oncogene).

ARHGF_HUMAN
NC score	0.411457 (rank : 55)	θ value	0.00175202 (rank : 73)
Query Neighborhood Hits	255	Target Neighborhood Hits	214	Shared Neighborhood Hits	64
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

ARHGC_MOUSE
NC score	0.409436 (rank : 56)	θ value	0.00175202 (rank : 72)
Query Neighborhood Hits	255	Target Neighborhood Hits	344	Shared Neighborhood Hits	82
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ITSN1_HUMAN
NC score	0.404160 (rank : 57)	θ value	4.45536e-07 (rank : 45)
Query Neighborhood Hits	255	Target Neighborhood Hits	1757	Shared Neighborhood Hits	195
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN1_MOUSE
NC score	0.402862 (rank : 58)	θ value	2.21117e-06 (rank : 51)
Query Neighborhood Hits	255	Target Neighborhood Hits	1669	Shared Neighborhood Hits	196
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

ARHG2_HUMAN
NC score	0.400964 (rank : 59)	θ value	0.0113563 (rank : 89)
Query Neighborhood Hits	255	Target Neighborhood Hits	142	Shared Neighborhood Hits	71
SwissProt Accessions	Q92974, O75142, Q15079	Gene names	ARHGEF2, KIAA0651, LFP40
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (GEF-H1 protein) (Proliferating cell nucleolar antigen p40).

ARHG1_MOUSE
NC score	0.399912 (rank : 60)	θ value	0.0961366 (rank : 111)
Query Neighborhood Hits	255	Target Neighborhood Hits	266	Shared Neighborhood Hits	68
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

RGNEF_MOUSE
NC score	0.398053 (rank : 61)	θ value	5.44631e-05 (rank : 56)
Query Neighborhood Hits	255	Target Neighborhood Hits	641	Shared Neighborhood Hits	127
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

FARP2_MOUSE
NC score	0.376570 (rank : 62)	θ value	1.87187e-05 (rank : 52)
Query Neighborhood Hits	255	Target Neighborhood Hits	209	Shared Neighborhood Hits	70
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FGD5_HUMAN
NC score	0.368354 (rank : 63)	θ value	0.0736092 (rank : 109)
Query Neighborhood Hits	255	Target Neighborhood Hits	235	Shared Neighborhood Hits	57
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

FGD5_MOUSE
NC score	0.358037 (rank : 64)	θ value	0.0113563 (rank : 90)
Query Neighborhood Hits	255	Target Neighborhood Hits	170	Shared Neighborhood Hits	54
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

FARP2_HUMAN
NC score	0.356290 (rank : 65)	θ value	3.19293e-05 (rank : 53)
Query Neighborhood Hits	255	Target Neighborhood Hits	240	Shared Neighborhood Hits	68
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

SPTA2_HUMAN
NC score	0.332500 (rank : 66)	θ value	2.28291e-11 (rank : 24)
Query Neighborhood Hits	255	Target Neighborhood Hits	888	Shared Neighborhood Hits	152
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

SPTA1_MOUSE
NC score	0.329631 (rank : 67)	θ value	2.61198e-07 (rank : 44)
Query Neighborhood Hits	255	Target Neighborhood Hits	675	Shared Neighborhood Hits	140
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

TRIO_HUMAN
NC score	0.324815 (rank : 68)	θ value	6.56568e-51 (rank : 4)
Query Neighborhood Hits	255	Target Neighborhood Hits	1580	Shared Neighborhood Hits	173
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

SPTA1_HUMAN
NC score	0.315903 (rank : 69)	θ value	3.19293e-05 (rank : 54)
Query Neighborhood Hits	255	Target Neighborhood Hits	748	Shared Neighborhood Hits	144
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

ABR_HUMAN
NC score	0.313710 (rank : 70)	θ value	0.0113563 (rank : 87)
Query Neighborhood Hits	255	Target Neighborhood Hits	166	Shared Neighborhood Hits	62
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

GNRP_MOUSE
NC score	0.313141 (rank : 71)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	255	Target Neighborhood Hits	191	Shared Neighborhood Hits	72
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

BCR_HUMAN
NC score	0.307327 (rank : 72)	θ value	0.0193708 (rank : 93)
Query Neighborhood Hits	255	Target Neighborhood Hits	204	Shared Neighborhood Hits	62
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

FARP1_HUMAN
NC score	0.306377 (rank : 73)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	255	Target Neighborhood Hits	241	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

GNRP_HUMAN
NC score	0.282582 (rank : 74)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	255	Target Neighborhood Hits	239	Shared Neighborhood Hits	73
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

DUET_HUMAN
NC score	0.273857 (rank : 75)	θ value	7.25919e-50 (rank : 5)
Query Neighborhood Hits	255	Target Neighborhood Hits	1220	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

NCF1_HUMAN
NC score	0.251849 (rank : 76)	θ value	7.1131e-05 (rank : 57)
Query Neighborhood Hits	255	Target Neighborhood Hits	198	Shared Neighborhood Hits	49
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

SPTN5_HUMAN
NC score	0.249341 (rank : 77)	θ value	3.19293e-05 (rank : 55)
Query Neighborhood Hits	255	Target Neighborhood Hits	674	Shared Neighborhood Hits	108
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

SPTB2_HUMAN
NC score	0.240979 (rank : 78)	θ value	0.0148317 (rank : 92)
Query Neighborhood Hits	255	Target Neighborhood Hits	748	Shared Neighborhood Hits	126
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SPTB2_MOUSE
NC score	0.239203 (rank : 79)	θ value	0.0431538 (rank : 101)
Query Neighborhood Hits	255	Target Neighborhood Hits	770	Shared Neighborhood Hits	122
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

NCF1_MOUSE
NC score	0.236270 (rank : 80)	θ value	0.00035302 (rank : 58)
Query Neighborhood Hits	255	Target Neighborhood Hits	198	Shared Neighborhood Hits	48
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

SPTB1_MOUSE
NC score	0.234781 (rank : 81)	θ value	0.00102713 (rank : 70)
Query Neighborhood Hits	255	Target Neighborhood Hits	543	Shared Neighborhood Hits	111
SwissProt Accessions	P15508	Gene names	Sptb, Spnb-1, Spnb1, Sptb1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

SPTB1_HUMAN
NC score	0.230321 (rank : 82)	θ value	0.00175202 (rank : 74)
Query Neighborhood Hits	255	Target Neighborhood Hits	541	Shared Neighborhood Hits	102
SwissProt Accessions	P11277, Q15510, Q15519	Gene names	SPTB, SPTB1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

SPTN4_HUMAN
NC score	0.222607 (rank : 83)	θ value	0.00390308 (rank : 76)
Query Neighborhood Hits	255	Target Neighborhood Hits	570	Shared Neighborhood Hits	103
SwissProt Accessions	Q9H254, Q9H1K7, Q9H1K8, Q9H1K9, Q9H3G8, Q9HCD0	Gene names	SPTBN4, KIAA1642, SPTBN3
Domain Architecture
Description	Spectrin beta chain, brain 3 (Spectrin, non-erythroid beta chain 3) (Beta-IV spectrin).

SPTN2_HUMAN
NC score	0.222447 (rank : 84)	θ value	0.21417 (rank : 134)
Query Neighborhood Hits	255	Target Neighborhood Hits	535	Shared Neighborhood Hits	101
SwissProt Accessions	O15020, O14872, O14873	Gene names	SPTBN2, KIAA0302
Domain Architecture
Description	Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).

BPA1_MOUSE
NC score	0.219104 (rank : 85)	θ value	0.00665767 (rank : 81)
Query Neighborhood Hits	255	Target Neighborhood Hits	1477	Shared Neighborhood Hits	142
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

MACF1_HUMAN
NC score	0.218982 (rank : 86)	θ value	0.00665767 (rank : 84)
Query Neighborhood Hits	255	Target Neighborhood Hits	1341	Shared Neighborhood Hits	139
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

SYNE1_HUMAN
NC score	0.212760 (rank : 87)	θ value	0.00665767 (rank : 86)
Query Neighborhood Hits	255	Target Neighborhood Hits	1484	Shared Neighborhood Hits	143
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

MACF4_HUMAN
NC score	0.212260 (rank : 88)	θ value	0.00665767 (rank : 85)
Query Neighborhood Hits	255	Target Neighborhood Hits	1321	Shared Neighborhood Hits	139
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MACF1_MOUSE
NC score	0.212181 (rank : 89)	θ value	0.0563607 (rank : 108)
Query Neighborhood Hits	255	Target Neighborhood Hits	1313	Shared Neighborhood Hits	133
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

BPAEA_HUMAN
NC score	0.211333 (rank : 90)	θ value	0.00102713 (rank : 69)
Query Neighborhood Hits	255	Target Neighborhood Hits	1369	Shared Neighborhood Hits	129
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

SOS1_HUMAN
NC score	0.206337 (rank : 91)	θ value	θ > 10 (rank : 807)
Query Neighborhood Hits	255	Target Neighborhood Hits	274	Shared Neighborhood Hits	44
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

SYNE2_HUMAN
NC score	0.196845 (rank : 92)	θ value	0.62314 (rank : 158)
Query Neighborhood Hits	255	Target Neighborhood Hits	1323	Shared Neighborhood Hits	134
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

SOS1_MOUSE
NC score	0.194264 (rank : 93)	θ value	θ > 10 (rank : 808)
Query Neighborhood Hits	255	Target Neighborhood Hits	281	Shared Neighborhood Hits	48
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

DMD_MOUSE
NC score	0.191300 (rank : 94)	θ value	1.81305 (rank : 183)
Query Neighborhood Hits	255	Target Neighborhood Hits	1111	Shared Neighborhood Hits	129
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

ACTN4_MOUSE
NC score	0.186784 (rank : 95)	θ value	0.0563607 (rank : 102)
Query Neighborhood Hits	255	Target Neighborhood Hits	276	Shared Neighborhood Hits	68
SwissProt Accessions	P57780	Gene names	Actn4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

ACTN1_HUMAN
NC score	0.186668 (rank : 96)	θ value	0.00102713 (rank : 67)
Query Neighborhood Hits	255	Target Neighborhood Hits	221	Shared Neighborhood Hits	54
SwissProt Accessions	P12814, Q9BTN1	Gene names	ACTN1
Domain Architecture
Description	Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein).

ACTN1_MOUSE
NC score	0.186156 (rank : 97)	θ value	0.00102713 (rank : 68)
Query Neighborhood Hits	255	Target Neighborhood Hits	216	Shared Neighborhood Hits	51
SwissProt Accessions	Q7TPR4	Gene names	Actn1
Domain Architecture
Description	Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein).

ACTN3_MOUSE
NC score	0.185247 (rank : 98)	θ value	0.21417 (rank : 124)
Query Neighborhood Hits	255	Target Neighborhood Hits	265	Shared Neighborhood Hits	67
SwissProt Accessions	O88990	Gene names	Actn3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

DMD_HUMAN
NC score	0.183707 (rank : 99)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	255	Target Neighborhood Hits	1135	Shared Neighborhood Hits	125
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

ACTN2_MOUSE
NC score	0.183578 (rank : 100)	θ value	0.00665767 (rank : 77)
Query Neighborhood Hits	255	Target Neighborhood Hits	287	Shared Neighborhood Hits	68
SwissProt Accessions	Q9JI91	Gene names	Actn2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

ACTN4_HUMAN
NC score	0.183498 (rank : 101)	θ value	0.163984 (rank : 121)
Query Neighborhood Hits	255	Target Neighborhood Hits	279	Shared Neighborhood Hits	67
SwissProt Accessions	O43707, O76048	Gene names	ACTN4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

SH3K1_HUMAN
NC score	0.183143 (rank : 102)	θ value	θ > 10 (rank : 785)
Query Neighborhood Hits	255	Target Neighborhood Hits	341	Shared Neighborhood Hits	62
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

ACTN2_HUMAN
NC score	0.182544 (rank : 103)	θ value	0.0113563 (rank : 88)
Query Neighborhood Hits	255	Target Neighborhood Hits	295	Shared Neighborhood Hits	64
SwissProt Accessions	P35609, Q86TF4, Q86TI8	Gene names	ACTN2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

UTRO_HUMAN
NC score	0.182190 (rank : 104)	θ value	θ > 10 (rank : 889)
Query Neighborhood Hits	255	Target Neighborhood Hits	960	Shared Neighborhood Hits	120
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

ACTN3_HUMAN
NC score	0.181934 (rank : 105)	θ value	0.00665767 (rank : 78)
Query Neighborhood Hits	255	Target Neighborhood Hits	272	Shared Neighborhood Hits	68
SwissProt Accessions	Q08043	Gene names	ACTN3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

EEA1_MOUSE
NC score	0.179035 (rank : 106)	θ value	0.000786445 (rank : 66)
Query Neighborhood Hits	255	Target Neighborhood Hits	1637	Shared Neighborhood Hits	145
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

SOS2_HUMAN
NC score	0.178879 (rank : 107)	θ value	θ > 10 (rank : 809)
Query Neighborhood Hits	255	Target Neighborhood Hits	193	Shared Neighborhood Hits	40
SwissProt Accessions	Q07890, Q15503	Gene names	SOS2
Domain Architecture
Description	Son of sevenless homolog 2 (SOS-2).

PLEC1_HUMAN
NC score	0.177986 (rank : 108)	θ value	3.0926 (rank : 201)
Query Neighborhood Hits	255	Target Neighborhood Hits	1326	Shared Neighborhood Hits	129
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

EEA1_HUMAN
NC score	0.174808 (rank : 109)	θ value	0.0431538 (rank : 96)
Query Neighborhood Hits	255	Target Neighborhood Hits	1796	Shared Neighborhood Hits	152
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

SH3K1_MOUSE
NC score	0.173859 (rank : 110)	θ value	θ > 10 (rank : 786)
Query Neighborhood Hits	255	Target Neighborhood Hits	332	Shared Neighborhood Hits	62
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

PPIP1_HUMAN
NC score	0.172576 (rank : 111)	θ value	0.0148317 (rank : 91)
Query Neighborhood Hits	255	Target Neighborhood Hits	389	Shared Neighborhood Hits	85
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

CD2AP_MOUSE
NC score	0.170163 (rank : 112)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	255	Target Neighborhood Hits	336	Shared Neighborhood Hits	58
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

CD2AP_HUMAN
NC score	0.169837 (rank : 113)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	255	Target Neighborhood Hits	315	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

PPIP1_MOUSE
NC score	0.161563 (rank : 114)	θ value	1.06291 (rank : 171)
Query Neighborhood Hits	255	Target Neighborhood Hits	377	Shared Neighborhood Hits	83
SwissProt Accessions	P97814, Q4V9R4	Gene names	Pstpip1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1).

GRAP_MOUSE
NC score	0.159511 (rank : 115)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	255	Target Neighborhood Hits	309	Shared Neighborhood Hits	51
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

SMC3_HUMAN
NC score	0.159352 (rank : 116)	θ value	5.81887e-07 (rank : 47)
Query Neighborhood Hits	255	Target Neighborhood Hits	1186	Shared Neighborhood Hits	127
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

GRAP_HUMAN
NC score	0.159242 (rank : 117)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	255	Target Neighborhood Hits	307	Shared Neighborhood Hits	50
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

SMC3_MOUSE
NC score	0.158940 (rank : 118)	θ value	5.81887e-07 (rank : 48)
Query Neighborhood Hits	255	Target Neighborhood Hits	1187	Shared Neighborhood Hits	128
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

GOGB1_HUMAN
NC score	0.158505 (rank : 119)	θ value	0.000461057 (rank : 61)
Query Neighborhood Hits	255	Target Neighborhood Hits	2297	Shared Neighborhood Hits	152
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

STAC_HUMAN
NC score	0.158382 (rank : 120)	θ value	θ > 10 (rank : 823)
Query Neighborhood Hits	255	Target Neighborhood Hits	276	Shared Neighborhood Hits	49
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

OBSCN_HUMAN
NC score	0.157982 (rank : 121)	θ value	1.12775e-26 (rank : 8)
Query Neighborhood Hits	255	Target Neighborhood Hits	1931	Shared Neighborhood Hits	82
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

NCF2_HUMAN
NC score	0.157220 (rank : 122)	θ value	θ > 10 (rank : 652)
Query Neighborhood Hits	255	Target Neighborhood Hits	229	Shared Neighborhood Hits	50
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

BPAEA_MOUSE
NC score	0.156845 (rank : 123)	θ value	0.00665767 (rank : 82)
Query Neighborhood Hits	255	Target Neighborhood Hits	1480	Shared Neighborhood Hits	127
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

FYCO1_MOUSE
NC score	0.156523 (rank : 124)	θ value	0.21417 (rank : 128)
Query Neighborhood Hits	255	Target Neighborhood Hits	1059	Shared Neighborhood Hits	131
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

SRBS1_HUMAN
NC score	0.156406 (rank : 125)	θ value	θ > 10 (rank : 814)
Query Neighborhood Hits	255	Target Neighborhood Hits	396	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

NUMA1_HUMAN
NC score	0.155000 (rank : 126)	θ value	0.00298849 (rank : 75)
Query Neighborhood Hits	255	Target Neighborhood Hits	1523	Shared Neighborhood Hits	135
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

NCF4_MOUSE
NC score	0.154471 (rank : 127)	θ value	θ > 10 (rank : 654)
Query Neighborhood Hits	255	Target Neighborhood Hits	177	Shared Neighborhood Hits	39
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

CYTSA_MOUSE
NC score	0.153209 (rank : 128)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	255	Target Neighborhood Hits	1104	Shared Neighborhood Hits	127
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

STAC_MOUSE
NC score	0.152391 (rank : 129)	θ value	θ > 10 (rank : 824)
Query Neighborhood Hits	255	Target Neighborhood Hits	268	Shared Neighborhood Hits	49
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

NCK1_HUMAN
NC score	0.152362 (rank : 130)	θ value	θ > 10 (rank : 655)
Query Neighborhood Hits	255	Target Neighborhood Hits	312	Shared Neighborhood Hits	51
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

NCF4_HUMAN
NC score	0.151695 (rank : 131)	θ value	θ > 10 (rank : 653)
Query Neighborhood Hits	255	Target Neighborhood Hits	161	Shared Neighborhood Hits	37
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

PEPL_MOUSE
NC score	0.151605 (rank : 132)	θ value	0.21417 (rank : 132)
Query Neighborhood Hits	255	Target Neighborhood Hits	1105	Shared Neighborhood Hits	123
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

VINEX_MOUSE
NC score	0.151327 (rank : 133)	θ value	θ > 10 (rank : 893)
Query Neighborhood Hits	255	Target Neighborhood Hits	286	Shared Neighborhood Hits	50
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

SRBS1_MOUSE
NC score	0.151312 (rank : 134)	θ value	θ > 10 (rank : 815)
Query Neighborhood Hits	255	Target Neighborhood Hits	409	Shared Neighborhood Hits	50
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

GCC2_MOUSE
NC score	0.151300 (rank : 135)	θ value	0.000461057 (rank : 60)
Query Neighborhood Hits	255	Target Neighborhood Hits	1619	Shared Neighborhood Hits	132
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

EVPL_HUMAN
NC score	0.151216 (rank : 136)	θ value	0.47712 (rank : 147)
Query Neighborhood Hits	255	Target Neighborhood Hits	895	Shared Neighborhood Hits	117
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

VINEX_HUMAN
NC score	0.151090 (rank : 137)	θ value	θ > 10 (rank : 892)
Query Neighborhood Hits	255	Target Neighborhood Hits	270	Shared Neighborhood Hits	52
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

PKHF2_HUMAN
NC score	0.150145 (rank : 138)	θ value	θ > 10 (rank : 711)
Query Neighborhood Hits	255	Target Neighborhood Hits	75	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H8W4	Gene names	PLEKHF2, ZFYVE18
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2) (PH and FYVE domain-containing protein 2) (Phafin-2) (Zinc finger FYVE domain-containing protein 18).

CYTSA_HUMAN
NC score	0.149818 (rank : 139)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	255	Target Neighborhood Hits	1138	Shared Neighborhood Hits	128
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

PKHF2_MOUSE
NC score	0.149545 (rank : 140)	θ value	θ > 10 (rank : 712)
Query Neighborhood Hits	255	Target Neighborhood Hits	77	Shared Neighborhood Hits	21
SwissProt Accessions	Q91WB4	Gene names	Plekhf2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2).

FYCO1_HUMAN
NC score	0.148981 (rank : 141)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	255	Target Neighborhood Hits	1149	Shared Neighborhood Hits	130
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

TRIPB_HUMAN
NC score	0.148331 (rank : 142)	θ value	0.62314 (rank : 159)
Query Neighborhood Hits	255	Target Neighborhood Hits	1587	Shared Neighborhood Hits	141
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

GRB2_HUMAN
NC score	0.147982 (rank : 143)	θ value	8.99809 (rank : 242)
Query Neighborhood Hits	255	Target Neighborhood Hits	310	Shared Neighborhood Hits	49
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
NC score	0.147808 (rank : 144)	θ value	8.99809 (rank : 243)
Query Neighborhood Hits	255	Target Neighborhood Hits	312	Shared Neighborhood Hits	49
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

PEPL_HUMAN
NC score	0.147497 (rank : 145)	θ value	0.163984 (rank : 123)
Query Neighborhood Hits	255	Target Neighborhood Hits	1141	Shared Neighborhood Hits	117
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

GOGA4_HUMAN
NC score	0.147494 (rank : 146)	θ value	0.62314 (rank : 153)
Query Neighborhood Hits	255	Target Neighborhood Hits	2034	Shared Neighborhood Hits	147
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

NCK2_HUMAN
NC score	0.147449 (rank : 147)	θ value	θ > 10 (rank : 656)
Query Neighborhood Hits	255	Target Neighborhood Hits	310	Shared Neighborhood Hits	51
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

CENPF_HUMAN
NC score	0.146673 (rank : 148)	θ value	0.00665767 (rank : 83)
Query Neighborhood Hits	255	Target Neighborhood Hits	1932	Shared Neighborhood Hits	142
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

PKHF1_HUMAN
NC score	0.146086 (rank : 149)	θ value	θ > 10 (rank : 709)
Query Neighborhood Hits	255	Target Neighborhood Hits	76	Shared Neighborhood Hits	21
SwissProt Accessions	Q96S99, Q96K11, Q9BUB9	Gene names	PLEKHF1, APPD, LAPF, ZFYVE15
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (PH and FYVE domain-containing protein 1) (Phafin-1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains) (Apoptosis-inducing protein) (Zinc finger FYVE domain-containing protein 15).

EVPL_MOUSE
NC score	0.145747 (rank : 150)	θ value	0.125558 (rank : 119)
Query Neighborhood Hits	255	Target Neighborhood Hits	952	Shared Neighborhood Hits	112
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

PKHF1_MOUSE
NC score	0.144524 (rank : 151)	θ value	θ > 10 (rank : 710)
Query Neighborhood Hits	255	Target Neighborhood Hits	80	Shared Neighborhood Hits	20
SwissProt Accessions	Q3TB82, Q99M16	Gene names	Plekhf1, Lapf
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains).

CP250_MOUSE
NC score	0.144198 (rank : 152)	θ value	2.36792 (rank : 188)
Query Neighborhood Hits	255	Target Neighborhood Hits	1583	Shared Neighborhood Hits	140
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

GOGA3_MOUSE
NC score	0.143497 (rank : 153)	θ value	0.163984 (rank : 122)
Query Neighborhood Hits	255	Target Neighborhood Hits	1437	Shared Neighborhood Hits	134
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

CP250_HUMAN
NC score	0.143209 (rank : 154)	θ value	1.81305 (rank : 180)
Query Neighborhood Hits	255	Target Neighborhood Hits	1805	Shared Neighborhood Hits	141
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

GCC2_HUMAN
NC score	0.140793 (rank : 155)	θ value	0.0431538 (rank : 97)
Query Neighborhood Hits	255	Target Neighborhood Hits	1558	Shared Neighborhood Hits	130
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

GRAP2_HUMAN
NC score	0.140218 (rank : 156)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	255	Target Neighborhood Hits	304	Shared Neighborhood Hits	47
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

RBP24_HUMAN
NC score	0.140165 (rank : 157)	θ value	0.0431538 (rank : 99)
Query Neighborhood Hits	255	Target Neighborhood Hits	1559	Shared Neighborhood Hits	129
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

GRAP2_MOUSE
NC score	0.139702 (rank : 158)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	255	Target Neighborhood Hits	297	Shared Neighborhood Hits	46
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

GOGA4_MOUSE
NC score	0.138421 (rank : 159)	θ value	0.279714 (rank : 137)
Query Neighborhood Hits	255	Target Neighborhood Hits	1939	Shared Neighborhood Hits	138
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

RUFY2_HUMAN
NC score	0.137974 (rank : 160)	θ value	θ > 10 (rank : 769)
Query Neighborhood Hits	255	Target Neighborhood Hits	1208	Shared Neighborhood Hits	123
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

KTN1_MOUSE
NC score	0.137295 (rank : 161)	θ value	0.21417 (rank : 130)
Query Neighborhood Hits	255	Target Neighborhood Hits	1324	Shared Neighborhood Hits	133
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

DESP_HUMAN
NC score	0.137265 (rank : 162)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	255	Target Neighborhood Hits	1470	Shared Neighborhood Hits	133
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

GOGA3_HUMAN
NC score	0.136803 (rank : 163)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	255	Target Neighborhood Hits	1317	Shared Neighborhood Hits	130
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

KTN1_HUMAN
NC score	0.136502 (rank : 164)	θ value	θ > 10 (rank : 560)
Query Neighborhood Hits	255	Target Neighborhood Hits	1197	Shared Neighborhood Hits	122
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

HMMR_MOUSE
NC score	0.134075 (rank : 165)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	255	Target Neighborhood Hits	1178	Shared Neighborhood Hits	131
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

AKAP9_HUMAN
NC score	0.133419 (rank : 166)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	255	Target Neighborhood Hits	1710	Shared Neighborhood Hits	141
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

NIN_HUMAN
NC score	0.131793 (rank : 167)	θ value	4.03905 (rank : 211)
Query Neighborhood Hits	255	Target Neighborhood Hits	1416	Shared Neighborhood Hits	126
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

STAC3_MOUSE
NC score	0.131503 (rank : 168)	θ value	θ > 10 (rank : 822)
Query Neighborhood Hits	255	Target Neighborhood Hits	232	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAM1_HUMAN
NC score	0.131500 (rank : 169)	θ value	θ > 10 (rank : 825)
Query Neighborhood Hits	255	Target Neighborhood Hits	271	Shared Neighborhood Hits	48
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

CEP63_HUMAN
NC score	0.131328 (rank : 170)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	255	Target Neighborhood Hits	1005	Shared Neighborhood Hits	120
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

CP135_MOUSE
NC score	0.131137 (rank : 171)	θ value	0.365318 (rank : 142)
Query Neighborhood Hits	255	Target Neighborhood Hits	1278	Shared Neighborhood Hits	123
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

STAM1_MOUSE
NC score	0.130968 (rank : 172)	θ value	θ > 10 (rank : 826)
Query Neighborhood Hits	255	Target Neighborhood Hits	273	Shared Neighborhood Hits	49
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

CENPE_HUMAN
NC score	0.130241 (rank : 173)	θ value	0.47712 (rank : 144)
Query Neighborhood Hits	255	Target Neighborhood Hits	2060	Shared Neighborhood Hits	147
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

STAC3_HUMAN
NC score	0.129972 (rank : 174)	θ value	θ > 10 (rank : 821)
Query Neighborhood Hits	255	Target Neighborhood Hits	228	Shared Neighborhood Hits	41
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

RAD50_HUMAN
NC score	0.129948 (rank : 175)	θ value	θ > 10 (rank : 732)
Query Neighborhood Hits	255	Target Neighborhood Hits	1317	Shared Neighborhood Hits	124
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

NPHP1_MOUSE
NC score	0.129922 (rank : 176)	θ value	θ > 10 (rank : 673)
Query Neighborhood Hits	255	Target Neighborhood Hits	267	Shared Neighborhood Hits	59
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

CRKL_HUMAN
NC score	0.129590 (rank : 177)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	255	Target Neighborhood Hits	313	Shared Neighborhood Hits	45
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

CF060_HUMAN
NC score	0.129572 (rank : 178)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	255	Target Neighborhood Hits	1270	Shared Neighborhood Hits	128
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

SRC8_HUMAN
NC score	0.129511 (rank : 179)	θ value	θ > 10 (rank : 816)
Query Neighborhood Hits	255	Target Neighborhood Hits	269	Shared Neighborhood Hits	49
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

REST_HUMAN
NC score	0.129397 (rank : 180)	θ value	0.0431538 (rank : 100)
Query Neighborhood Hits	255	Target Neighborhood Hits	1605	Shared Neighborhood Hits	132
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

GOGA1_HUMAN
NC score	0.129281 (rank : 181)	θ value	0.47712 (rank : 148)
Query Neighborhood Hits	255	Target Neighborhood Hits	1222	Shared Neighborhood Hits	129
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

RUFY1_HUMAN
NC score	0.129219 (rank : 182)	θ value	θ > 10 (rank : 767)
Query Neighborhood Hits	255	Target Neighborhood Hits	848	Shared Neighborhood Hits	119
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

CE290_HUMAN
NC score	0.129024 (rank : 183)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	255	Target Neighborhood Hits	1553	Shared Neighborhood Hits	134
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

RAD50_MOUSE
NC score	0.128682 (rank : 184)	θ value	θ > 10 (rank : 733)
Query Neighborhood Hits	255	Target Neighborhood Hits	1366	Shared Neighborhood Hits	127
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

CROCC_MOUSE
NC score	0.128078 (rank : 185)	θ value	1.81305 (rank : 182)
Query Neighborhood Hits	255	Target Neighborhood Hits	1460	Shared Neighborhood Hits	132
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

HCLS1_MOUSE
NC score	0.127833 (rank : 186)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	255	Target Neighborhood Hits	329	Shared Neighborhood Hits	47
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

REST_MOUSE
NC score	0.127776 (rank : 187)	θ value	θ > 10 (rank : 749)
Query Neighborhood Hits	255	Target Neighborhood Hits	1506	Shared Neighborhood Hits	125
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

CROCC_HUMAN
NC score	0.127736 (rank : 188)	θ value	1.81305 (rank : 181)
Query Neighborhood Hits	255	Target Neighborhood Hits	1409	Shared Neighborhood Hits	130
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CRKL_MOUSE
NC score	0.127118 (rank : 189)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	255	Target Neighborhood Hits	307	Shared Neighborhood Hits	47
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

NIN_MOUSE
NC score	0.126847 (rank : 190)	θ value	0.279714 (rank : 140)
Query Neighborhood Hits	255	Target Neighborhood Hits	1376	Shared Neighborhood Hits	123
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

HOOK3_MOUSE
NC score	0.126797 (rank : 191)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	255	Target Neighborhood Hits	1007	Shared Neighborhood Hits	119
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

RUFY1_MOUSE
NC score	0.126666 (rank : 192)	θ value	θ > 10 (rank : 768)
Query Neighborhood Hits	255	Target Neighborhood Hits	765	Shared Neighborhood Hits	118
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

CK5P2_MOUSE
NC score	0.126595 (rank : 193)	θ value	0.125558 (rank : 118)
Query Neighborhood Hits	255	Target Neighborhood Hits	1151	Shared Neighborhood Hits	115
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

BCAR1_MOUSE
NC score	0.126546 (rank : 194)	θ value	0.21417 (rank : 125)
Query Neighborhood Hits	255	Target Neighborhood Hits	438	Shared Neighborhood Hits	52
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CRK_MOUSE
NC score	0.126199 (rank : 195)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	255	Target Neighborhood Hits	314	Shared Neighborhood Hits	49
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

PCNT_HUMAN
NC score	0.126009 (rank : 196)	θ value	3.0926 (rank : 200)
Query Neighborhood Hits	255	Target Neighborhood Hits	1551	Shared Neighborhood Hits	132
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

CE152_HUMAN
NC score	0.125930 (rank : 197)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	255	Target Neighborhood Hits	976	Shared Neighborhood Hits	111
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

SRC8_MOUSE
NC score	0.125786 (rank : 198)	θ value	θ > 10 (rank : 817)
Query Neighborhood Hits	255	Target Neighborhood Hits	292	Shared Neighborhood Hits	48
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

HOOK1_HUMAN
NC score	0.125634 (rank : 199)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	255	Target Neighborhood Hits	942	Shared Neighborhood Hits	118
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

HOOK3_HUMAN
NC score	0.125413 (rank : 200)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	255	Target Neighborhood Hits	1070	Shared Neighborhood Hits	119
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

GRAP1_HUMAN
NC score	0.125332 (rank : 201)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	255	Target Neighborhood Hits	944	Shared Neighborhood Hits	119
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

RUFY2_MOUSE
NC score	0.124954 (rank : 202)	θ value	θ > 10 (rank : 770)
Query Neighborhood Hits	255	Target Neighborhood Hits	820	Shared Neighborhood Hits	112
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

CP135_HUMAN
NC score	0.124705 (rank : 203)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	255	Target Neighborhood Hits	1290	Shared Neighborhood Hits	130
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

SWP70_MOUSE
NC score	0.124482 (rank : 204)	θ value	0.21417 (rank : 135)
Query Neighborhood Hits	255	Target Neighborhood Hits	1097	Shared Neighborhood Hits	126
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

HOOK1_MOUSE
NC score	0.124099 (rank : 205)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	255	Target Neighborhood Hits	910	Shared Neighborhood Hits	121
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

HCLS1_HUMAN
NC score	0.124092 (rank : 206)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	255	Target Neighborhood Hits	358	Shared Neighborhood Hits	45
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

SH3G1_HUMAN
NC score	0.123623 (rank : 207)	θ value	θ > 10 (rank : 779)
Query Neighborhood Hits	255	Target Neighborhood Hits	307	Shared Neighborhood Hits	70
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

STAM2_MOUSE
NC score	0.123229 (rank : 208)	θ value	θ > 10 (rank : 828)
Query Neighborhood Hits	255	Target Neighborhood Hits	285	Shared Neighborhood Hits	53
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

HMMR_HUMAN
NC score	0.122612 (rank : 209)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	255	Target Neighborhood Hits	1082	Shared Neighborhood Hits	124
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

PIBF1_HUMAN
NC score	0.122611 (rank : 210)	θ value	θ > 10 (rank : 703)
Query Neighborhood Hits	255	Target Neighborhood Hits	1041	Shared Neighborhood Hits	122
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

FLIP1_HUMAN
NC score	0.122518 (rank : 211)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	255	Target Neighborhood Hits	1405	Shared Neighborhood Hits	133
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

BCAR1_HUMAN
NC score	0.122416 (rank : 212)	θ value	0.125558 (rank : 117)
Query Neighborhood Hits	255	Target Neighborhood Hits	554	Shared Neighborhood Hits	51
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CCD46_HUMAN
NC score	0.122392 (rank : 213)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	255	Target Neighborhood Hits	1430	Shared Neighborhood Hits	126
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

CJ118_MOUSE
NC score	0.122361 (rank : 214)	θ value	1.06291 (rank : 164)
Query Neighborhood Hits	255	Target Neighborhood Hits	1132	Shared Neighborhood Hits	115
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

CRK_HUMAN
NC score	0.122131 (rank : 215)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	255	Target Neighborhood Hits	308	Shared Neighborhood Hits	48
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

RB6I2_HUMAN
NC score	0.122051 (rank : 216)	θ value	0.813845 (rank : 162)
Query Neighborhood Hits	255	Target Neighborhood Hits	1584	Shared Neighborhood Hits	130
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

SWP70_HUMAN
NC score	0.121826 (rank : 217)	θ value	θ > 10 (rank : 835)
Query Neighborhood Hits	255	Target Neighborhood Hits	973	Shared Neighborhood Hits	123
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

CR034_MOUSE
NC score	0.121453 (rank : 218)	θ value	1.38821 (rank : 174)
Query Neighborhood Hits	255	Target Neighborhood Hits	643	Shared Neighborhood Hits	102
SwissProt Accessions	Q8CDV0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34 homolog.

RB6I2_MOUSE
NC score	0.121370 (rank : 219)	θ value	5.27518 (rank : 225)
Query Neighborhood Hits	255	Target Neighborhood Hits	1433	Shared Neighborhood Hits	126
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

TPR_HUMAN
NC score	0.121158 (rank : 220)	θ value	θ > 10 (rank : 870)
Query Neighborhood Hits	255	Target Neighborhood Hits	1921	Shared Neighborhood Hits	140
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

CK5P2_HUMAN
NC score	0.121127 (rank : 221)	θ value	0.21417 (rank : 126)
Query Neighborhood Hits	255	Target Neighborhood Hits	1433	Shared Neighborhood Hits	126
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

STAM2_HUMAN
NC score	0.121126 (rank : 222)	θ value	θ > 10 (rank : 827)
Query Neighborhood Hits	255	Target Neighborhood Hits	288	Shared Neighborhood Hits	52
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

ERC2_MOUSE
NC score	0.120780 (rank : 223)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	255	Target Neighborhood Hits	1166	Shared Neighborhood Hits	118
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

GOGA1_MOUSE
NC score	0.120441 (rank : 224)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	255	Target Neighborhood Hits	994	Shared Neighborhood Hits	119
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

GRAP1_MOUSE
NC score	0.120436 (rank : 225)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	255	Target Neighborhood Hits	1234	Shared Neighborhood Hits	129
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

PCNT_MOUSE
NC score	0.120319 (rank : 226)	θ value	θ > 10 (rank : 695)
Query Neighborhood Hits	255	Target Neighborhood Hits	1207	Shared Neighborhood Hits	126
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

HOOK2_MOUSE
NC score	0.120119 (rank : 227)	θ value	0.0961366 (rank : 112)
Query Neighborhood Hits	255	Target Neighborhood Hits	736	Shared Neighborhood Hits	103
SwissProt Accessions	Q7TMK6, Q8BY47, Q8R347, Q8VCN4, Q99LU2	Gene names	Hook2
Domain Architecture
Description	Hook homolog 2.

RABE1_HUMAN
NC score	0.119510 (rank : 228)	θ value	5.27518 (rank : 224)
Query Neighborhood Hits	255	Target Neighborhood Hits	1104	Shared Neighborhood Hits	124
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

CING_MOUSE
NC score	0.119204 (rank : 229)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	255	Target Neighborhood Hits	1432	Shared Neighborhood Hits	131
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

RIMB1_MOUSE
NC score	0.119168 (rank : 230)	θ value	θ > 10 (rank : 756)
Query Neighborhood Hits	255	Target Neighborhood Hits	1376	Shared Neighborhood Hits	142
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

ERC2_HUMAN
NC score	0.119023 (rank : 231)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	255	Target Neighborhood Hits	1156	Shared Neighborhood Hits	117
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

CING_HUMAN
NC score	0.118977 (rank : 232)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	255	Target Neighborhood Hits	1275	Shared Neighborhood Hits	123
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

LIPA2_HUMAN
NC score	0.118921 (rank : 233)	θ value	0.279714 (rank : 139)
Query Neighborhood Hits	255	Target Neighborhood Hits	1044	Shared Neighborhood Hits	109
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

SYCP1_MOUSE
NC score	0.118589 (rank : 234)	θ value	θ > 10 (rank : 837)
Query Neighborhood Hits	255	Target Neighborhood Hits	1456	Shared Neighborhood Hits	128
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

CI093_HUMAN
NC score	0.118522 (rank : 235)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	255	Target Neighborhood Hits	1088	Shared Neighborhood Hits	123
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

SH3G1_MOUSE
NC score	0.118386 (rank : 236)	θ value	θ > 10 (rank : 780)
Query Neighborhood Hits	255	Target Neighborhood Hits	291	Shared Neighborhood Hits	63
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

SDCG8_HUMAN
NC score	0.118233 (rank : 237)	θ value	θ > 10 (rank : 776)
Query Neighborhood Hits	255	Target Neighborhood Hits	1002	Shared Neighborhood Hits	115
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

CI039_HUMAN
NC score	0.118224 (rank : 238)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	255	Target Neighborhood Hits	1171	Shared Neighborhood Hits	120
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

CCD39_MOUSE
NC score	0.118082 (rank : 239)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	255	Target Neighborhood Hits	1026	Shared Neighborhood Hits	109
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

SH3G3_MOUSE
NC score	0.117652 (rank : 240)	θ value	θ > 10 (rank : 784)
Query Neighborhood Hits	255	Target Neighborhood Hits	236	Shared Neighborhood Hits	48
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

TMF1_HUMAN
NC score	0.117522 (rank : 241)	θ value	θ > 10 (rank : 857)
Query Neighborhood Hits	255	Target Neighborhood Hits	987	Shared Neighborhood Hits	111
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

GOGA2_MOUSE
NC score	0.117498 (rank : 242)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	255	Target Neighborhood Hits	944	Shared Neighborhood Hits	116
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

SH3G2_HUMAN
NC score	0.117466 (rank : 243)	θ value	θ > 10 (rank : 781)
Query Neighborhood Hits	255	Target Neighborhood Hits	324	Shared Neighborhood Hits	63
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

ABI2_HUMAN
NC score	0.117119 (rank : 244)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	255	Target Neighborhood Hits	350	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

CN145_HUMAN
NC score	0.117063 (rank : 245)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	255	Target Neighborhood Hits	1196	Shared Neighborhood Hits	124
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

IFT74_HUMAN
NC score	0.116894 (rank : 246)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	255	Target Neighborhood Hits	949	Shared Neighborhood Hits	117
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

ABI2_MOUSE
NC score	0.116809 (rank : 247)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	255	Target Neighborhood Hits	266	Shared Neighborhood Hits	47
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

CCD41_MOUSE
NC score	0.116123 (rank : 248)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	255	Target Neighborhood Hits	1399	Shared Neighborhood Hits	121
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

CCD46_MOUSE
NC score	0.116070 (rank : 249)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	255	Target Neighborhood Hits	1405	Shared Neighborhood Hits	127
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

GOGA6_HUMAN
NC score	0.115953 (rank : 250)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	255	Target Neighborhood Hits	1007	Shared Neighborhood Hits	113
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

RABE1_MOUSE
NC score	0.115905 (rank : 251)	θ value	θ > 10 (rank : 729)
Query Neighborhood Hits	255	Target Neighborhood Hits	1105	Shared Neighborhood Hits	120
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

SH3G3_HUMAN
NC score	0.115757 (rank : 252)	θ value	θ > 10 (rank : 783)
Query Neighborhood Hits	255	Target Neighborhood Hits	222	Shared Neighborhood Hits	49
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

NEBL_HUMAN
NC score	0.115269 (rank : 253)	θ value	θ > 10 (rank : 664)
Query Neighborhood Hits	255	Target Neighborhood Hits	457	Shared Neighborhood Hits	92
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

LIPA2_MOUSE
NC score	0.115217 (rank : 254)	θ value	0.0563607 (rank : 106)
Query Neighborhood Hits	255	Target Neighborhood Hits	1282	Shared Neighborhood Hits	118
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

RBCC1_MOUSE
NC score	0.115181 (rank : 255)	θ value	θ > 10 (rank : 742)
Query Neighborhood Hits	255	Target Neighborhood Hits	1048	Shared Neighborhood Hits	122
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

FLIP1_MOUSE
NC score	0.114774 (rank : 256)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	255	Target Neighborhood Hits	1176	Shared Neighborhood Hits	122
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

TRHY_HUMAN
NC score	0.114485 (rank : 257)	θ value	θ > 10 (rank : 876)
Query Neighborhood Hits	255	Target Neighborhood Hits	1385	Shared Neighborhood Hits	117
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

AZI1_HUMAN
NC score	0.114235 (rank : 258)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	255	Target Neighborhood Hits	1000	Shared Neighborhood Hits	118
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

IFT81_MOUSE
NC score	0.114081 (rank : 259)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	255	Target Neighborhood Hits	959	Shared Neighborhood Hits	114
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

MD1L1_MOUSE
NC score	0.113871 (rank : 260)	θ value	θ > 10 (rank : 601)
Query Neighborhood Hits	255	Target Neighborhood Hits	1001	Shared Neighborhood Hits	116
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

CYLN2_HUMAN
NC score	0.113583 (rank : 261)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	255	Target Neighborhood Hits	1004	Shared Neighborhood Hits	116
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

K0555_HUMAN
NC score	0.113447 (rank : 262)	θ value	θ > 10 (rank : 538)
Query Neighborhood Hits	255	Target Neighborhood Hits	880	Shared Neighborhood Hits	118
SwissProt Accessions	Q96AA8, O60302	Gene names	KIAA0555
Domain Architecture	No domain graphic available
Description	Protein KIAA0555.

SDCG8_MOUSE
NC score	0.113184 (rank : 263)	θ value	0.813845 (rank : 163)
Query Neighborhood Hits	255	Target Neighborhood Hits	886	Shared Neighborhood Hits	110
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

CCD39_HUMAN
NC score	0.113162 (rank : 264)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	255	Target Neighborhood Hits	868	Shared Neighborhood Hits	106
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

HOOK2_HUMAN
NC score	0.113118 (rank : 265)	θ value	0.21417 (rank : 129)
Query Neighborhood Hits	255	Target Neighborhood Hits	714	Shared Neighborhood Hits	104
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

CLMN_HUMAN
NC score	0.112968 (rank : 266)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	255	Target Neighborhood Hits	205	Shared Neighborhood Hits	26
SwissProt Accessions	Q96JQ2, Q9H713, Q9HA23, Q9HA57, Q9UFP4, Q9ULN2	Gene names	CLMN, KIAA1188
Domain Architecture
Description	Calmin.

GOGA2_HUMAN
NC score	0.112956 (rank : 267)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	255	Target Neighborhood Hits	856	Shared Neighborhood Hits	108
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

KMHN1_MOUSE
NC score	0.112750 (rank : 268)	θ value	8.99809 (rank : 248)
Query Neighborhood Hits	255	Target Neighborhood Hits	949	Shared Neighborhood Hits	122
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

MD1L1_HUMAN
NC score	0.112702 (rank : 269)	θ value	θ > 10 (rank : 600)
Query Neighborhood Hits	255	Target Neighborhood Hits	893	Shared Neighborhood Hits	115
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

SH3G2_MOUSE
NC score	0.112684 (rank : 270)	θ value	θ > 10 (rank : 782)
Query Neighborhood Hits	255	Target Neighborhood Hits	319	Shared Neighborhood Hits	63
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

CJ118_HUMAN
NC score	0.112643 (rank : 271)	θ value	6.88961 (rank : 230)
Query Neighborhood Hits	255	Target Neighborhood Hits	937	Shared Neighborhood Hits	112
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

ABI1_MOUSE
NC score	0.112637 (rank : 272)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	255	Target Neighborhood Hits	246	Shared Neighborhood Hits	47
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

OPTN_MOUSE
NC score	0.112489 (rank : 273)	θ value	θ > 10 (rank : 680)
Query Neighborhood Hits	255	Target Neighborhood Hits	1120	Shared Neighborhood Hits	115
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

TAXB1_MOUSE
NC score	0.112424 (rank : 274)	θ value	0.279714 (rank : 141)
Query Neighborhood Hits	255	Target Neighborhood Hits	886	Shared Neighborhood Hits	102
SwissProt Accessions	Q3UKC1, Q91YT6, Q9CVF0, Q9DC45	Gene names	Tax1bp1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 homolog.

CASL_HUMAN
NC score	0.112144 (rank : 275)	θ value	4.03905 (rank : 206)
Query Neighborhood Hits	255	Target Neighborhood Hits	259	Shared Neighborhood Hits	45
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

CCD91_MOUSE
NC score	0.111984 (rank : 276)	θ value	6.88961 (rank : 227)
Query Neighborhood Hits	255	Target Neighborhood Hits	699	Shared Neighborhood Hits	95
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

CCD41_HUMAN
NC score	0.111797 (rank : 277)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	255	Target Neighborhood Hits	1139	Shared Neighborhood Hits	123
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

IFT74_MOUSE
NC score	0.111650 (rank : 278)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	255	Target Neighborhood Hits	939	Shared Neighborhood Hits	123
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

SMC2_HUMAN
NC score	0.111457 (rank : 279)	θ value	θ > 10 (rank : 799)
Query Neighborhood Hits	255	Target Neighborhood Hits	1405	Shared Neighborhood Hits	117
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

GOGA5_HUMAN
NC score	0.111222 (rank : 280)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	255	Target Neighborhood Hits	1168	Shared Neighborhood Hits	122
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

CCD21_HUMAN
NC score	0.111171 (rank : 281)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	255	Target Neighborhood Hits	1228	Shared Neighborhood Hits	127
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

RIMB1_HUMAN
NC score	0.111170 (rank : 282)	θ value	θ > 10 (rank : 755)
Query Neighborhood Hits	255	Target Neighborhood Hits	1479	Shared Neighborhood Hits	144
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

CCD13_HUMAN
NC score	0.111125 (rank : 283)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	255	Target Neighborhood Hits	721	Shared Neighborhood Hits	100
SwissProt Accessions	Q8IYE1	Gene names	CCDC13
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 13.

CCD21_MOUSE
NC score	0.111027 (rank : 284)	θ value	0.279714 (rank : 136)
Query Neighborhood Hits	255	Target Neighborhood Hits	1135	Shared Neighborhood Hits	122
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

INVO_HUMAN
NC score	0.110796 (rank : 285)	θ value	θ > 10 (rank : 531)
Query Neighborhood Hits	255	Target Neighborhood Hits	636	Shared Neighborhood Hits	92
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

CCHCR_HUMAN
NC score	0.110739 (rank : 286)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	255	Target Neighborhood Hits	717	Shared Neighborhood Hits	104
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

SMC1A_HUMAN
NC score	0.110402 (rank : 287)	θ value	θ > 10 (rank : 797)
Query Neighborhood Hits	255	Target Neighborhood Hits	1346	Shared Neighborhood Hits	123
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

CLMN_MOUSE
NC score	0.110307 (rank : 288)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	255	Target Neighborhood Hits	180	Shared Neighborhood Hits	24
SwissProt Accessions	Q8C5W0, Q91V71, Q91XT7, Q91XT8, Q91XU9	Gene names	Clmn
Domain Architecture
Description	Calmin.

CYLN2_MOUSE
NC score	0.110267 (rank : 289)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	255	Target Neighborhood Hits	1002	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

GOGA5_MOUSE
NC score	0.110249 (rank : 290)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	255	Target Neighborhood Hits	1434	Shared Neighborhood Hits	123
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

SMC1A_MOUSE
NC score	0.109685 (rank : 291)	θ value	θ > 10 (rank : 798)
Query Neighborhood Hits	255	Target Neighborhood Hits	1384	Shared Neighborhood Hits	121
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

TUFT1_HUMAN
NC score	0.109607 (rank : 292)	θ value	1.38821 (rank : 178)
Query Neighborhood Hits	255	Target Neighborhood Hits	686	Shared Neighborhood Hits	104
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

CN145_MOUSE
NC score	0.109350 (rank : 293)	θ value	8.99809 (rank : 241)
Query Neighborhood Hits	255	Target Neighborhood Hits	916	Shared Neighborhood Hits	112
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

MY18A_HUMAN
NC score	0.109053 (rank : 294)	θ value	θ > 10 (rank : 627)
Query Neighborhood Hits	255	Target Neighborhood Hits	1929	Shared Neighborhood Hits	138
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYH10_MOUSE
NC score	0.108719 (rank : 295)	θ value	5.27518 (rank : 221)
Query Neighborhood Hits	255	Target Neighborhood Hits	1612	Shared Neighborhood Hits	140
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

SYCP1_HUMAN
NC score	0.108632 (rank : 296)	θ value	θ > 10 (rank : 836)
Query Neighborhood Hits	255	Target Neighborhood Hits	1313	Shared Neighborhood Hits	117
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

IFT81_HUMAN
NC score	0.108310 (rank : 297)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	255	Target Neighborhood Hits	893	Shared Neighborhood Hits	114
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

CASL_MOUSE
NC score	0.108196 (rank : 298)	θ value	4.03905 (rank : 207)
Query Neighborhood Hits	255	Target Neighborhood Hits	225	Shared Neighborhood Hits	40
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

KMHN1_HUMAN
NC score	0.107655 (rank : 299)	θ value	θ > 10 (rank : 557)
Query Neighborhood Hits	255	Target Neighborhood Hits	950	Shared Neighborhood Hits	112
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

SMC4_HUMAN
NC score	0.107535 (rank : 300)	θ value	θ > 10 (rank : 801)
Query Neighborhood Hits	255	Target Neighborhood Hits	937	Shared Neighborhood Hits	111
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

LIPA1_HUMAN
NC score	0.107511 (rank : 301)	θ value	θ > 10 (rank : 570)
Query Neighborhood Hits	255	Target Neighborhood Hits	1294	Shared Neighborhood Hits	118
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

CASP_HUMAN
NC score	0.107382 (rank : 302)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	255	Target Neighborhood Hits	1131	Shared Neighborhood Hits	119
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

SM1L2_HUMAN
NC score	0.107371 (rank : 303)	θ value	θ > 10 (rank : 795)
Query Neighborhood Hits	255	Target Neighborhood Hits	1019	Shared Neighborhood Hits	112
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

EP15R_HUMAN
NC score	0.107236 (rank : 304)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	255	Target Neighborhood Hits	1083	Shared Neighborhood Hits	117
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

OSTF1_HUMAN
NC score	0.107178 (rank : 305)	θ value	θ > 10 (rank : 681)
Query Neighborhood Hits	255	Target Neighborhood Hits	466	Shared Neighborhood Hits	46
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

CASP_MOUSE
NC score	0.107075 (rank : 306)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	255	Target Neighborhood Hits	1152	Shared Neighborhood Hits	120
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

SM1L2_MOUSE
NC score	0.106562 (rank : 307)	θ value	θ > 10 (rank : 796)
Query Neighborhood Hits	255	Target Neighborhood Hits	918	Shared Neighborhood Hits	107
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

AZI1_MOUSE
NC score	0.106417 (rank : 308)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	255	Target Neighborhood Hits	990	Shared Neighborhood Hits	117
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

EP15_MOUSE
NC score	0.106280 (rank : 309)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	255	Target Neighborhood Hits	820	Shared Neighborhood Hits	108
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

PLCG1_MOUSE
NC score	0.106276 (rank : 310)	θ value	θ > 10 (rank : 715)
Query Neighborhood Hits	255	Target Neighborhood Hits	314	Shared Neighborhood Hits	44
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

CCD62_HUMAN
NC score	0.106207 (rank : 311)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	255	Target Neighborhood Hits	631	Shared Neighborhood Hits	98
SwissProt Accessions	Q6P9F0, Q6ZVF2, Q86VJ0, Q9BYZ5	Gene names	CCDC62
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60 (Aaa-protein) (Protein TSP- NY).

MYH10_HUMAN
NC score	0.106172 (rank : 312)	θ value	θ > 10 (rank : 630)
Query Neighborhood Hits	255	Target Neighborhood Hits	1620	Shared Neighborhood Hits	138
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH8_HUMAN
NC score	0.106076 (rank : 313)	θ value	0.0961366 (rank : 115)
Query Neighborhood Hits	255	Target Neighborhood Hits	1610	Shared Neighborhood Hits	136
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH3_HUMAN
NC score	0.106022 (rank : 314)	θ value	2.36792 (rank : 191)
Query Neighborhood Hits	255	Target Neighborhood Hits	1660	Shared Neighborhood Hits	134
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

ZN291_HUMAN
NC score	0.105869 (rank : 315)	θ value	8.99809 (rank : 255)
Query Neighborhood Hits	255	Target Neighborhood Hits	647	Shared Neighborhood Hits	101
SwissProt Accessions	Q9BY12	Gene names	ZNF291
Domain Architecture
Description	Zinc finger protein 291.

RBCC1_HUMAN
NC score	0.105832 (rank : 316)	θ value	θ > 10 (rank : 741)
Query Neighborhood Hits	255	Target Neighborhood Hits	1023	Shared Neighborhood Hits	120
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

MYH8_MOUSE
NC score	0.105803 (rank : 317)	θ value	0.0961366 (rank : 116)
Query Neighborhood Hits	255	Target Neighborhood Hits	1600	Shared Neighborhood Hits	137
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

OSTF1_MOUSE
NC score	0.105792 (rank : 318)	θ value	θ > 10 (rank : 682)
Query Neighborhood Hits	255	Target Neighborhood Hits	467	Shared Neighborhood Hits	46
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

MYH7_HUMAN
NC score	0.105396 (rank : 319)	θ value	θ > 10 (rank : 641)
Query Neighborhood Hits	255	Target Neighborhood Hits	1559	Shared Neighborhood Hits	133
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

CCD91_HUMAN
NC score	0.105299 (rank : 320)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	255	Target Neighborhood Hits	868	Shared Neighborhood Hits	105
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

SPAG5_MOUSE
NC score	0.105264 (rank : 321)	θ value	θ > 10 (rank : 811)
Query Neighborhood Hits	255	Target Neighborhood Hits	612	Shared Neighborhood Hits	95
SwissProt Accessions	Q7TME2, Q8CH61	Gene names	Spag5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Mastrin) (Mitotic spindle-associated protein p126) (MAP126).

EP15R_MOUSE
NC score	0.105217 (rank : 322)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	255	Target Neighborhood Hits	1135	Shared Neighborhood Hits	115
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

AHI1_HUMAN
NC score	0.105217 (rank : 323)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	255	Target Neighborhood Hits	537	Shared Neighborhood Hits	54
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

PLCG1_HUMAN
NC score	0.105211 (rank : 324)	θ value	θ > 10 (rank : 714)
Query Neighborhood Hits	255	Target Neighborhood Hits	293	Shared Neighborhood Hits	44
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

SMOO_HUMAN
NC score	0.105008 (rank : 325)	θ value	θ > 10 (rank : 803)
Query Neighborhood Hits	255	Target Neighborhood Hits	391	Shared Neighborhood Hits	36
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

GAS8_HUMAN
NC score	0.104844 (rank : 326)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	255	Target Neighborhood Hits	819	Shared Neighborhood Hits	108
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

MYH11_HUMAN
NC score	0.104815 (rank : 327)	θ value	θ > 10 (rank : 631)
Query Neighborhood Hits	255	Target Neighborhood Hits	1806	Shared Neighborhood Hits	139
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH2_HUMAN
NC score	0.104374 (rank : 328)	θ value	0.21417 (rank : 131)
Query Neighborhood Hits	255	Target Neighborhood Hits	1491	Shared Neighborhood Hits	133
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

CCHCR_MOUSE
NC score	0.104018 (rank : 329)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	255	Target Neighborhood Hits	932	Shared Neighborhood Hits	107
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

ABI1_HUMAN
NC score	0.103685 (rank : 330)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	255	Target Neighborhood Hits	257	Shared Neighborhood Hits	45
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

MY18A_MOUSE
NC score	0.103626 (rank : 331)	θ value	θ > 10 (rank : 628)
Query Neighborhood Hits	255	Target Neighborhood Hits	1989	Shared Neighborhood Hits	136
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

CNTRB_MOUSE
NC score	0.103574 (rank : 332)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	255	Target Neighborhood Hits	1029	Shared Neighborhood Hits	114
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

MYH6_MOUSE
NC score	0.103482 (rank : 333)	θ value	θ > 10 (rank : 640)
Query Neighborhood Hits	255	Target Neighborhood Hits	1501	Shared Neighborhood Hits	133
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

CCD19_HUMAN
NC score	0.103143 (rank : 334)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	255	Target Neighborhood Hits	639	Shared Neighborhood Hits	101
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

CT032_HUMAN
NC score	0.103134 (rank : 335)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	255	Target Neighborhood Hits	235	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

TAXB1_HUMAN
NC score	0.102909 (rank : 336)	θ value	θ > 10 (rank : 848)
Query Neighborhood Hits	255	Target Neighborhood Hits	829	Shared Neighborhood Hits	93
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

MYH11_MOUSE
NC score	0.102860 (rank : 337)	θ value	θ > 10 (rank : 632)
Query Neighborhood Hits	255	Target Neighborhood Hits	1777	Shared Neighborhood Hits	139
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

EP15_HUMAN
NC score	0.102643 (rank : 338)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	255	Target Neighborhood Hits	1021	Shared Neighborhood Hits	116
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

RRBP1_HUMAN
NC score	0.102206 (rank : 339)	θ value	θ > 10 (rank : 765)
Query Neighborhood Hits	255	Target Neighborhood Hits	1306	Shared Neighborhood Hits	116
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

SMC2_MOUSE
NC score	0.102169 (rank : 340)	θ value	θ > 10 (rank : 800)
Query Neighborhood Hits	255	Target Neighborhood Hits	1131	Shared Neighborhood Hits	112
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

OPTN_HUMAN
NC score	0.102109 (rank : 341)	θ value	θ > 10 (rank : 679)
Query Neighborhood Hits	255	Target Neighborhood Hits	827	Shared Neighborhood Hits	97
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

MYH13_HUMAN
NC score	0.102028 (rank : 342)	θ value	2.36792 (rank : 190)
Query Neighborhood Hits	255	Target Neighborhood Hits	1504	Shared Neighborhood Hits	133
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

SAS6_MOUSE
NC score	0.101796 (rank : 343)	θ value	θ > 10 (rank : 775)
Query Neighborhood Hits	255	Target Neighborhood Hits	931	Shared Neighborhood Hits	110
SwissProt Accessions	Q80UK7, Q9CYT4	Gene names	Sass6, Sas6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog.

NEMO_HUMAN
NC score	0.101605 (rank : 344)	θ value	θ > 10 (rank : 666)
Query Neighborhood Hits	255	Target Neighborhood Hits	820	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

BRE1A_MOUSE
NC score	0.101549 (rank : 345)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	255	Target Neighborhood Hits	1025	Shared Neighborhood Hits	114
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

LIPA3_HUMAN
NC score	0.101464 (rank : 346)	θ value	0.0961366 (rank : 114)
Query Neighborhood Hits	255	Target Neighborhood Hits	828	Shared Neighborhood Hits	103
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

CR034_HUMAN
NC score	0.100976 (rank : 347)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	255	Target Neighborhood Hits	538	Shared Neighborhood Hits	89
SwissProt Accessions	Q5BJE1, Q6ZP67, Q6ZU20	Gene names	C18orf34
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34.

LRC45_HUMAN
NC score	0.100861 (rank : 348)	θ value	θ > 10 (rank : 583)
Query Neighborhood Hits	255	Target Neighborhood Hits	933	Shared Neighborhood Hits	112
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

AHI1_MOUSE
NC score	0.100813 (rank : 349)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	255	Target Neighborhood Hits	496	Shared Neighborhood Hits	52
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

MYH1_HUMAN
NC score	0.100808 (rank : 350)	θ value	θ > 10 (rank : 635)
Query Neighborhood Hits	255	Target Neighborhood Hits	1478	Shared Neighborhood Hits	126
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

NPHP1_HUMAN
NC score	0.100556 (rank : 351)	θ value	θ > 10 (rank : 672)
Query Neighborhood Hits	255	Target Neighborhood Hits	288	Shared Neighborhood Hits	63
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

ZFY28_HUMAN
NC score	0.100487 (rank : 352)	θ value	θ > 10 (rank : 909)
Query Neighborhood Hits	255	Target Neighborhood Hits	152	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HCC9	Gene names	ZFYVE28, KIAA1643
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 28.

SMC4_MOUSE
NC score	0.100471 (rank : 353)	θ value	θ > 10 (rank : 802)
Query Neighborhood Hits	255	Target Neighborhood Hits	830	Shared Neighborhood Hits	105
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

CCD96_MOUSE
NC score	0.100463 (rank : 354)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	255	Target Neighborhood Hits	704	Shared Neighborhood Hits	96
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

LUZP1_MOUSE
NC score	0.100202 (rank : 355)	θ value	θ > 10 (rank : 589)
Query Neighborhood Hits	255	Target Neighborhood Hits	940	Shared Neighborhood Hits	109
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

MYH6_HUMAN
NC score	0.100042 (rank : 356)	θ value	θ > 10 (rank : 639)
Query Neighborhood Hits	255	Target Neighborhood Hits	1426	Shared Neighborhood Hits	130
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

BRE1A_HUMAN
NC score	0.099949 (rank : 357)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	255	Target Neighborhood Hits	1071	Shared Neighborhood Hits	117
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

NUF2_MOUSE
NC score	0.099871 (rank : 358)	θ value	θ > 10 (rank : 676)
Query Neighborhood Hits	255	Target Neighborhood Hits	585	Shared Neighborhood Hits	95
SwissProt Accessions	Q99P69, Q8BTK7, Q8VE05, Q9CST5	Gene names	Cdca1, Nuf2r
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (Cell division cycle-associated protein 1).

MYH1_MOUSE
NC score	0.099811 (rank : 359)	θ value	θ > 10 (rank : 636)
Query Neighborhood Hits	255	Target Neighborhood Hits	1461	Shared Neighborhood Hits	127
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

OFD1_HUMAN
NC score	0.099754 (rank : 360)	θ value	θ > 10 (rank : 678)
Query Neighborhood Hits	255	Target Neighborhood Hits	753	Shared Neighborhood Hits	105
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

MYH9_HUMAN
NC score	0.099461 (rank : 361)	θ value	θ > 10 (rank : 642)
Query Neighborhood Hits	255	Target Neighborhood Hits	1762	Shared Neighborhood Hits	140
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH4_HUMAN
NC score	0.099242 (rank : 362)	θ value	θ > 10 (rank : 637)
Query Neighborhood Hits	255	Target Neighborhood Hits	1377	Shared Neighborhood Hits	130
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

PLCG2_HUMAN
NC score	0.099239 (rank : 363)	θ value	θ > 10 (rank : 716)
Query Neighborhood Hits	255	Target Neighborhood Hits	280	Shared Neighborhood Hits	38
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

IF3A_MOUSE
NC score	0.098813 (rank : 364)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	255	Target Neighborhood Hits	871	Shared Neighborhood Hits	104
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

DYNA_HUMAN
NC score	0.098712 (rank : 365)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	255	Target Neighborhood Hits	1194	Shared Neighborhood Hits	124
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

NEMO_MOUSE
NC score	0.098486 (rank : 366)	θ value	3.0926 (rank : 199)
Query Neighborhood Hits	255	Target Neighborhood Hits	658	Shared Neighborhood Hits	104
SwissProt Accessions	O88522	Gene names	Ikbkg, Nemo
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (mFIP-3).

INCE_HUMAN
NC score	0.098370 (rank : 367)	θ value	θ > 10 (rank : 529)
Query Neighborhood Hits	255	Target Neighborhood Hits	978	Shared Neighborhood Hits	105
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

CALD1_HUMAN
NC score	0.098303 (rank : 368)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	255	Target Neighborhood Hits	959	Shared Neighborhood Hits	105
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

BICD1_HUMAN
NC score	0.098245 (rank : 369)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	255	Target Neighborhood Hits	844	Shared Neighborhood Hits	102
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

ZFYV9_HUMAN
NC score	0.098156 (rank : 370)	θ value	θ > 10 (rank : 912)
Query Neighborhood Hits	255	Target Neighborhood Hits	134	Shared Neighborhood Hits	17
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

NOXO1_HUMAN
NC score	0.098134 (rank : 371)	θ value	θ > 10 (rank : 670)
Query Neighborhood Hits	255	Target Neighborhood Hits	100	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NFA2, Q86YM1, Q8NFA3, Q96B73	Gene names	NOXO1, P41NOX
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Nox-organizing protein 1) (NADPH oxidase regulatory protein).

MPP9_HUMAN
NC score	0.098090 (rank : 372)	θ value	θ > 10 (rank : 621)
Query Neighborhood Hits	255	Target Neighborhood Hits	529	Shared Neighborhood Hits	91
SwissProt Accessions	Q99550, Q9H976	Gene names	MPHOSPH9, MPP9
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 9.

MYH4_MOUSE
NC score	0.097923 (rank : 373)	θ value	θ > 10 (rank : 638)
Query Neighborhood Hits	255	Target Neighborhood Hits	1476	Shared Neighborhood Hits	130
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

RFIP3_HUMAN
NC score	0.097880 (rank : 374)	θ value	θ > 10 (rank : 750)
Query Neighborhood Hits	255	Target Neighborhood Hits	1055	Shared Neighborhood Hits	113
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

TUFT1_MOUSE
NC score	0.097860 (rank : 375)	θ value	θ > 10 (rank : 879)
Query Neighborhood Hits	255	Target Neighborhood Hits	732	Shared Neighborhood Hits	103
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

MILK2_HUMAN
NC score	0.097820 (rank : 376)	θ value	θ > 10 (rank : 614)
Query Neighborhood Hits	255	Target Neighborhood Hits	457	Shared Neighborhood Hits	44
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

BICD1_MOUSE
NC score	0.097723 (rank : 377)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	255	Target Neighborhood Hits	837	Shared Neighborhood Hits	102
SwissProt Accessions	Q8BR07, O55206, Q8BQ18, Q8BRR8, Q8C4D3, Q8CAK6, Q8R2J4, Q8R2J5, Q8R2J6, Q91YP7	Gene names	Bicd1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

MYH9_MOUSE
NC score	0.097531 (rank : 378)	θ value	θ > 10 (rank : 643)
Query Neighborhood Hits	255	Target Neighborhood Hits	1829	Shared Neighborhood Hits	140
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

CKAP4_MOUSE
NC score	0.097274 (rank : 379)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	255	Target Neighborhood Hits	596	Shared Neighborhood Hits	98
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

DBNL_HUMAN
NC score	0.097255 (rank : 380)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	255	Target Neighborhood Hits	244	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

CCD11_HUMAN
NC score	0.097188 (rank : 381)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	255	Target Neighborhood Hits	822	Shared Neighborhood Hits	110
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CKAP4_HUMAN
NC score	0.097127 (rank : 382)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	255	Target Neighborhood Hits	592	Shared Neighborhood Hits	93
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

RRBP1_MOUSE
NC score	0.097080 (rank : 383)	θ value	θ > 10 (rank : 766)
Query Neighborhood Hits	255	Target Neighborhood Hits	1650	Shared Neighborhood Hits	124
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

INCE_MOUSE
NC score	0.097027 (rank : 384)	θ value	θ > 10 (rank : 530)
Query Neighborhood Hits	255	Target Neighborhood Hits	903	Shared Neighborhood Hits	111
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

DBNL_MOUSE
NC score	0.097025 (rank : 385)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	255	Target Neighborhood Hits	306	Shared Neighborhood Hits	51
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

PACN2_HUMAN
NC score	0.097004 (rank : 386)	θ value	θ > 10 (rank : 691)
Query Neighborhood Hits	255	Target Neighborhood Hits	339	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

ASPP1_MOUSE
NC score	0.096980 (rank : 387)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	255	Target Neighborhood Hits	1244	Shared Neighborhood Hits	118
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ASPP1_HUMAN
NC score	0.096974 (rank : 388)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	255	Target Neighborhood Hits	956	Shared Neighborhood Hits	109
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

NAF1_MOUSE
NC score	0.096585 (rank : 389)	θ value	θ > 10 (rank : 651)
Query Neighborhood Hits	255	Target Neighborhood Hits	852	Shared Neighborhood Hits	100
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

GCC1_HUMAN
NC score	0.096475 (rank : 390)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	255	Target Neighborhood Hits	887	Shared Neighborhood Hits	104
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

CCD27_HUMAN
NC score	0.096462 (rank : 391)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	255	Target Neighborhood Hits	594	Shared Neighborhood Hits	98
SwissProt Accessions	Q2M243, Q5TBV3, Q96M50	Gene names	CCDC27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

PACN2_MOUSE
NC score	0.096433 (rank : 392)	θ value	θ > 10 (rank : 692)
Query Neighborhood Hits	255	Target Neighborhood Hits	382	Shared Neighborhood Hits	72
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

LMO7_HUMAN
NC score	0.096270 (rank : 393)	θ value	θ > 10 (rank : 582)
Query Neighborhood Hits	255	Target Neighborhood Hits	507	Shared Neighborhood Hits	69
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

UACA_HUMAN
NC score	0.096265 (rank : 394)	θ value	θ > 10 (rank : 887)
Query Neighborhood Hits	255	Target Neighborhood Hits	1622	Shared Neighborhood Hits	127
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

ANR26_MOUSE
NC score	0.096082 (rank : 395)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	255	Target Neighborhood Hits	1554	Shared Neighborhood Hits	134
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

MIPO1_HUMAN
NC score	0.096071 (rank : 396)	θ value	θ > 10 (rank : 615)
Query Neighborhood Hits	255	Target Neighborhood Hits	486	Shared Neighborhood Hits	83
SwissProt Accessions	Q8TD10, Q7Z3J0, Q8IV14	Gene names	MIPOL1
Domain Architecture	No domain graphic available
Description	Mirror-image polydactyly gene 1 protein.

NOXO1_MOUSE
NC score	0.095980 (rank : 397)	θ value	θ > 10 (rank : 671)
Query Neighborhood Hits	255	Target Neighborhood Hits	114	Shared Neighborhood Hits	30
SwissProt Accessions	Q8VCM2, Q3TZA4, Q8BH41, Q9D747	Gene names	Noxo1, Snx28
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Sorting nexin-28).

ABI3_HUMAN
NC score	0.095832 (rank : 398)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	255	Target Neighborhood Hits	227	Shared Neighborhood Hits	37
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

C102B_HUMAN
NC score	0.095826 (rank : 399)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	255	Target Neighborhood Hits	542	Shared Neighborhood Hits	87
SwissProt Accessions	Q68D86, Q7Z467, Q8NDK7, Q9H5C1	Gene names	CCDC102B, C18orf14
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 102B.

CNTRB_HUMAN
NC score	0.095792 (rank : 400)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	255	Target Neighborhood Hits	690	Shared Neighborhood Hits	96
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

ABI3_MOUSE
NC score	0.095621 (rank : 401)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	255	Target Neighborhood Hits	227	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

IF3A_HUMAN
NC score	0.095619 (rank : 402)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	255	Target Neighborhood Hits	875	Shared Neighborhood Hits	103
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

DYNA_MOUSE
NC score	0.095619 (rank : 403)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	255	Target Neighborhood Hits	1084	Shared Neighborhood Hits	118
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

CEP55_MOUSE
NC score	0.095497 (rank : 404)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	255	Target Neighborhood Hits	693	Shared Neighborhood Hits	96
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

KINH_HUMAN
NC score	0.095444 (rank : 405)	θ value	θ > 10 (rank : 555)
Query Neighborhood Hits	255	Target Neighborhood Hits	1231	Shared Neighborhood Hits	126
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

MYH14_MOUSE
NC score	0.095413 (rank : 406)	θ value	θ > 10 (rank : 634)
Query Neighborhood Hits	255	Target Neighborhood Hits	1225	Shared Neighborhood Hits	126
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

CARD9_HUMAN
NC score	0.095320 (rank : 407)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	255	Target Neighborhood Hits	602	Shared Neighborhood Hits	93
SwissProt Accessions	Q9H257, Q5SXM6, Q9H854	Gene names	CARD9
Domain Architecture
Description	Caspase recruitment domain-containing protein 9 (hCARD9).

MILK1_HUMAN
NC score	0.095274 (rank : 408)	θ value	θ > 10 (rank : 612)
Query Neighborhood Hits	255	Target Neighborhood Hits	427	Shared Neighborhood Hits	34
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

UACA_MOUSE
NC score	0.095209 (rank : 409)	θ value	θ > 10 (rank : 888)
Query Neighborhood Hits	255	Target Neighborhood Hits	1620	Shared Neighborhood Hits	132
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

SAS6_HUMAN
NC score	0.094976 (rank : 410)	θ value	θ > 10 (rank : 774)
Query Neighborhood Hits	255	Target Neighborhood Hits	791	Shared Neighborhood Hits	105
SwissProt Accessions	Q6UVJ0, Q8N3K0	Gene names	SASS6, SAS6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog (HsSAS-6).

ASPP2_HUMAN
NC score	0.094964 (rank : 411)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	255	Target Neighborhood Hits	1156	Shared Neighborhood Hits	124
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

KNTC2_HUMAN
NC score	0.094724 (rank : 412)	θ value	θ > 10 (rank : 558)
Query Neighborhood Hits	255	Target Neighborhood Hits	673	Shared Neighborhood Hits	96
SwissProt Accessions	O14777, Q6PJX2	Gene names	KNTC2, HEC, HEC1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cancer protein) (Retinoblastoma-associated protein HEC).

NAF1_HUMAN
NC score	0.094583 (rank : 413)	θ value	θ > 10 (rank : 650)
Query Neighborhood Hits	255	Target Neighborhood Hits	937	Shared Neighborhood Hits	101
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

LRC45_MOUSE
NC score	0.094346 (rank : 414)	θ value	θ > 10 (rank : 584)
Query Neighborhood Hits	255	Target Neighborhood Hits	959	Shared Neighborhood Hits	108
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

RPGR1_HUMAN
NC score	0.094262 (rank : 415)	θ value	θ > 10 (rank : 763)
Query Neighborhood Hits	255	Target Neighborhood Hits	578	Shared Neighborhood Hits	95
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

KNTC2_MOUSE
NC score	0.094245 (rank : 416)	θ value	θ > 10 (rank : 559)
Query Neighborhood Hits	255	Target Neighborhood Hits	692	Shared Neighborhood Hits	101
SwissProt Accessions	Q9D0F1, Q3TQT6, Q3UWM5, Q99P70	Gene names	Kntc2, Hec1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (Kinetochore-associated protein 2).

LRRF2_HUMAN
NC score	0.094196 (rank : 417)	θ value	θ > 10 (rank : 586)
Query Neighborhood Hits	255	Target Neighborhood Hits	791	Shared Neighborhood Hits	102
SwissProt Accessions	Q9Y608, Q68CV3, Q9NXH5	Gene names	LRRFIP2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

TEX9_MOUSE
NC score	0.094097 (rank : 418)	θ value	θ > 10 (rank : 856)
Query Neighborhood Hits	255	Target Neighborhood Hits	581	Shared Neighborhood Hits	92
SwissProt Accessions	Q9D845, O54764	Gene names	Tex9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein (Testis-specifically expressed protein 1) (Tsec-1).

NUF2_HUMAN
NC score	0.093877 (rank : 419)	θ value	θ > 10 (rank : 675)
Query Neighborhood Hits	255	Target Neighborhood Hits	661	Shared Neighborhood Hits	95
SwissProt Accessions	Q9BZD4, Q8WU69, Q96HJ4, Q96Q78	Gene names	CDCA1, NUF2, NUF2R
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1).

BRE1B_HUMAN
NC score	0.093613 (rank : 420)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	255	Target Neighborhood Hits	1040	Shared Neighborhood Hits	103
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

PACN1_HUMAN
NC score	0.093494 (rank : 421)	θ value	θ > 10 (rank : 689)
Query Neighborhood Hits	255	Target Neighborhood Hits	320	Shared Neighborhood Hits	70
SwissProt Accessions	Q9BY11, Q9P2G8	Gene names	PACSIN1, KIAA1379
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

KIF5C_MOUSE
NC score	0.093436 (rank : 422)	θ value	θ > 10 (rank : 551)
Query Neighborhood Hits	255	Target Neighborhood Hits	1040	Shared Neighborhood Hits	119
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

CUTL1_HUMAN
NC score	0.093422 (rank : 423)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	255	Target Neighborhood Hits	1574	Shared Neighborhood Hits	126
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

TPM2_HUMAN
NC score	0.093405 (rank : 424)	θ value	θ > 10 (rank : 864)
Query Neighborhood Hits	255	Target Neighborhood Hits	677	Shared Neighborhood Hits	101
SwissProt Accessions	P07951, P06468, Q13894, Q53FM4, Q5TCU4, Q5TCU7, Q9UH67	Gene names	TPM2, TMSB
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

ANR26_HUMAN
NC score	0.093361 (rank : 425)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	255	Target Neighborhood Hits	1614	Shared Neighborhood Hits	128
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ZFY16_MOUSE
NC score	0.093331 (rank : 426)	θ value	θ > 10 (rank : 904)
Query Neighborhood Hits	255	Target Neighborhood Hits	108	Shared Neighborhood Hits	16
SwissProt Accessions	Q80U44, Q8BRD2, Q8CG97	Gene names	Zfyve16, Kiaa0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosomal- associated FYVE domain protein).

CCD96_HUMAN
NC score	0.093172 (rank : 427)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	255	Target Neighborhood Hits	595	Shared Neighborhood Hits	87
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

KIF5C_HUMAN
NC score	0.093164 (rank : 428)	θ value	θ > 10 (rank : 550)
Query Neighborhood Hits	255	Target Neighborhood Hits	974	Shared Neighborhood Hits	121
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

CDR2_MOUSE
NC score	0.092941 (rank : 429)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	255	Target Neighborhood Hits	482	Shared Neighborhood Hits	89
SwissProt Accessions	P97817	Gene names	Cdr2
Domain Architecture	No domain graphic available
Description	Cerebellar degeneration-related protein 2.

SPAG5_HUMAN
NC score	0.092876 (rank : 430)	θ value	θ > 10 (rank : 810)
Query Neighborhood Hits	255	Target Neighborhood Hits	625	Shared Neighborhood Hits	99
SwissProt Accessions	Q96R06, O95213, Q9BWE8, Q9NT17, Q9UFE6	Gene names	SPAG5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Astrin) (Mitotic spindle-associated protein p126) (MAP126) (Deepest).

TSC1_HUMAN
NC score	0.092572 (rank : 431)	θ value	θ > 10 (rank : 877)
Query Neighborhood Hits	255	Target Neighborhood Hits	765	Shared Neighborhood Hits	95
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

ANM2_HUMAN
NC score	0.092505 (rank : 432)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	255	Target Neighborhood Hits	175	Shared Neighborhood Hits	39
SwissProt Accessions	P55345, P78350, Q9BW15, Q9UMC2	Gene names	PRMT2, HMT1, HRMT1L1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

TPM3_HUMAN
NC score	0.092386 (rank : 433)	θ value	θ > 10 (rank : 866)
Query Neighborhood Hits	255	Target Neighborhood Hits	689	Shared Neighborhood Hits	102
SwissProt Accessions	P06753, P12324, Q969Q2, Q9NQH8	Gene names	TPM3
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma) (hTM5).

TRAK1_HUMAN
NC score	0.092326 (rank : 434)	θ value	θ > 10 (rank : 873)
Query Neighborhood Hits	255	Target Neighborhood Hits	660	Shared Neighborhood Hits	102
SwissProt Accessions	Q9UPV9, Q96B69	Gene names	TRAK1, KIAA1042, OIP106
Domain Architecture	No domain graphic available
Description	Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase- interacting protein).

TPM3_MOUSE
NC score	0.092117 (rank : 435)	θ value	θ > 10 (rank : 867)
Query Neighborhood Hits	255	Target Neighborhood Hits	676	Shared Neighborhood Hits	100
SwissProt Accessions	P21107, Q09021, Q60606, Q80SW6, Q9EPW3	Gene names	Tpm3, Tpm-5, Tpm5
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma).

CCD27_MOUSE
NC score	0.092090 (rank : 436)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	255	Target Neighborhood Hits	461	Shared Neighborhood Hits	86
SwissProt Accessions	Q3V036	Gene names	Ccdc27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

CEP55_HUMAN
NC score	0.092089 (rank : 437)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	255	Target Neighborhood Hits	504	Shared Neighborhood Hits	86
SwissProt Accessions	Q53EZ4, Q32WF5, Q3MV20, Q5VY28, Q6N034, Q96H32, Q9NVS7	Gene names	CEP55, C10orf3, URCC6
Domain Architecture	No domain graphic available
Description	Centrosome protein 55 (Up-regulated in colon cancer 6).

BI2L1_HUMAN
NC score	0.092060 (rank : 438)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	255	Target Neighborhood Hits	156	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UHR4, Q75L21, Q75L22, Q96CV4, Q9Y2M8	Gene names	BAIAP2L1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

EFS_MOUSE
NC score	0.092050 (rank : 439)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	255	Target Neighborhood Hits	389	Shared Neighborhood Hits	49
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

HIP1R_MOUSE
NC score	0.091856 (rank : 440)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	255	Target Neighborhood Hits	959	Shared Neighborhood Hits	108
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

ZFY21_MOUSE
NC score	0.091852 (rank : 441)	θ value	θ > 10 (rank : 908)
Query Neighborhood Hits	255	Target Neighborhood Hits	72	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VCM3, Q9D1E2	Gene names	Zfyve21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

HIP1_HUMAN
NC score	0.091832 (rank : 442)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	255	Target Neighborhood Hits	1016	Shared Neighborhood Hits	107
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

CCD11_MOUSE
NC score	0.091671 (rank : 443)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	255	Target Neighborhood Hits	498	Shared Neighborhood Hits	89
SwissProt Accessions	Q9D439	Gene names	Ccdc11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

JIP3_MOUSE
NC score	0.091379 (rank : 444)	θ value	1.06291 (rank : 168)
Query Neighborhood Hits	255	Target Neighborhood Hits	759	Shared Neighborhood Hits	98
SwissProt Accessions	Q9ESN9, Q99KU7, Q9EQD8, Q9ESN7, Q9ESN8, Q9ESP0, Q9JLH2, Q9JLH3, Q9R0U7	Gene names	Mapk8ip3, Jip3, Jsap1, Syd2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3) (JNK/SAPK-associated protein 1) (JSAP1) (Sunday driver 2).

KIF4A_HUMAN
NC score	0.091322 (rank : 445)	θ value	θ > 10 (rank : 548)
Query Neighborhood Hits	255	Target Neighborhood Hits	1159	Shared Neighborhood Hits	115
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

TPM2_MOUSE
NC score	0.091266 (rank : 446)	θ value	θ > 10 (rank : 865)
Query Neighborhood Hits	255	Target Neighborhood Hits	676	Shared Neighborhood Hits	100
SwissProt Accessions	P58774, P02560, P46901	Gene names	Tpm2, Tpm-2
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

CTGE5_MOUSE
NC score	0.091143 (rank : 447)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	255	Target Neighborhood Hits	928	Shared Neighborhood Hits	106
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

ZFY16_HUMAN
NC score	0.091079 (rank : 448)	θ value	θ > 10 (rank : 903)
Query Neighborhood Hits	255	Target Neighborhood Hits	125	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z3T8, O15023, Q7LAU7, Q86T69, Q8N5L3, Q8NEK3	Gene names	ZFYVE16, KIAA0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome- associated FYVE domain protein).

XE7_HUMAN
NC score	0.091064 (rank : 449)	θ value	θ > 10 (rank : 898)
Query Neighborhood Hits	255	Target Neighborhood Hits	738	Shared Neighborhood Hits	95
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

EFS_HUMAN
NC score	0.091038 (rank : 450)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	255	Target Neighborhood Hits	348	Shared Neighborhood Hits	46
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

KIF5A_HUMAN
NC score	0.090650 (rank : 451)	θ value	0.0431538 (rank : 98)
Query Neighborhood Hits	255	Target Neighborhood Hits	843	Shared Neighborhood Hits	115
SwissProt Accessions	Q12840, Q4LE26	Gene names	KIF5A, NKHC1
Domain Architecture
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

BICD2_MOUSE
NC score	0.090649 (rank : 452)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	255	Target Neighborhood Hits	864	Shared Neighborhood Hits	104
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

T3JAM_HUMAN
NC score	0.090543 (rank : 453)	θ value	θ > 10 (rank : 838)
Query Neighborhood Hits	255	Target Neighborhood Hits	533	Shared Neighborhood Hits	90
SwissProt Accessions	Q9Y228, Q2YDB5, Q4VY06, Q7Z706	Gene names	TRAF3IP3, T3JAM
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

MILK1_MOUSE
NC score	0.090428 (rank : 454)	θ value	θ > 10 (rank : 613)
Query Neighborhood Hits	255	Target Neighborhood Hits	788	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

GOG8A_HUMAN
NC score	0.090272 (rank : 455)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	255	Target Neighborhood Hits	635	Shared Neighborhood Hits	98
SwissProt Accessions	Q9NZW0, O94937, Q9NZG8, Q9NZW3	Gene names	GOLGA8A, KIAA0855
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 8A/B (Golgi autoantigen golgin-67) (88 kDa Golgi protein) (Gm88 autoantigen).

P85B_HUMAN
NC score	0.090149 (rank : 456)	θ value	θ > 10 (rank : 687)
Query Neighborhood Hits	255	Target Neighborhood Hits	543	Shared Neighborhood Hits	92
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

GCC1_MOUSE
NC score	0.090127 (rank : 457)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	255	Target Neighborhood Hits	777	Shared Neighborhood Hits	100
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

KINH_MOUSE
NC score	0.090053 (rank : 458)	θ value	θ > 10 (rank : 556)
Query Neighborhood Hits	255	Target Neighborhood Hits	1082	Shared Neighborhood Hits	121
SwissProt Accessions	Q61768, O08711, Q61580	Gene names	Kif5b, Khcs, Kns1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

CUTL1_MOUSE
NC score	0.089997 (rank : 459)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	255	Target Neighborhood Hits	1620	Shared Neighborhood Hits	118
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

ZFY21_HUMAN
NC score	0.089985 (rank : 460)	θ value	θ > 10 (rank : 907)
Query Neighborhood Hits	255	Target Neighborhood Hits	72	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BQ24, Q86T05, Q96LT1	Gene names	ZFYVE21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

PACN3_HUMAN
NC score	0.089927 (rank : 461)	θ value	θ > 10 (rank : 693)
Query Neighborhood Hits	255	Target Neighborhood Hits	385	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

CDR2_HUMAN
NC score	0.089698 (rank : 462)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	255	Target Neighborhood Hits	404	Shared Neighborhood Hits	87
SwissProt Accessions	Q01850, Q13977	Gene names	CDR2, PCD17
Domain Architecture	No domain graphic available
Description	Cerebellar degeneration-related protein 2 (Paraneoplastic cerebellar degeneration-associated antigen) (Major Yo paraneoplastic antigen).

PACN3_MOUSE
NC score	0.089409 (rank : 463)	θ value	θ > 10 (rank : 694)
Query Neighborhood Hits	255	Target Neighborhood Hits	380	Shared Neighborhood Hits	71
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

MY18B_HUMAN
NC score	0.089192 (rank : 464)	θ value	θ > 10 (rank : 629)
Query Neighborhood Hits	255	Target Neighborhood Hits	1299	Shared Neighborhood Hits	116
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

RHG04_HUMAN
NC score	0.089144 (rank : 465)	θ value	θ > 10 (rank : 753)
Query Neighborhood Hits	255	Target Neighborhood Hits	307	Shared Neighborhood Hits	54
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

GAS8_MOUSE
NC score	0.089056 (rank : 466)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	255	Target Neighborhood Hits	622	Shared Neighborhood Hits	96
SwissProt Accessions	Q60779, Q99L71	Gene names	Gas8, Gas11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

BICD2_HUMAN
NC score	0.088875 (rank : 467)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	255	Target Neighborhood Hits	856	Shared Neighborhood Hits	104
SwissProt Accessions	Q8TD16, O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561	Gene names	BICD2, KIAA0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

TPM1_HUMAN
NC score	0.088822 (rank : 468)	θ value	θ > 10 (rank : 862)
Query Neighborhood Hits	255	Target Neighborhood Hits	716	Shared Neighborhood Hits	102
SwissProt Accessions	P09493, P09494, P10469, Q86W64, Q96IK2, Q9UCY9	Gene names	TPM1, TMSA
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

MICA1_MOUSE
NC score	0.088819 (rank : 469)	θ value	θ > 10 (rank : 608)
Query Neighborhood Hits	255	Target Neighborhood Hits	400	Shared Neighborhood Hits	82
SwissProt Accessions	Q8VDP3	Gene names	Mical1, Mical, Nical
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

PEX13_HUMAN
NC score	0.088749 (rank : 470)	θ value	θ > 10 (rank : 697)
Query Neighborhood Hits	255	Target Neighborhood Hits	128	Shared Neighborhood Hits	36
SwissProt Accessions	Q92968	Gene names	PEX13
Domain Architecture
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

CCDC6_HUMAN
NC score	0.088707 (rank : 471)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	255	Target Neighborhood Hits	723	Shared Neighborhood Hits	96
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

LIPA3_MOUSE
NC score	0.088559 (rank : 472)	θ value	θ > 10 (rank : 571)
Query Neighborhood Hits	255	Target Neighborhood Hits	636	Shared Neighborhood Hits	96
SwissProt Accessions	P60469	Gene names	Ppfia3
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

RABE2_MOUSE
NC score	0.088393 (rank : 473)	θ value	θ > 10 (rank : 731)
Query Neighborhood Hits	255	Target Neighborhood Hits	598	Shared Neighborhood Hits	92
SwissProt Accessions	Q91WG2, Q99KN3	Gene names	Rabep2, Rabpt5b
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

ZWINT_MOUSE
NC score	0.088296 (rank : 474)	θ value	θ > 10 (rank : 915)
Query Neighborhood Hits	255	Target Neighborhood Hits	497	Shared Neighborhood Hits	85
SwissProt Accessions	Q9CQU5, Q3UYT8, Q91VI4, Q9D0W9	Gene names	Zwint, D10Ertd749e
Domain Architecture	No domain graphic available
Description	ZW10 interactor (ZW10-interacting protein 1) (Zwint-1).

SHAN2_MOUSE
NC score	0.088173 (rank : 475)	θ value	θ > 10 (rank : 788)
Query Neighborhood Hits	255	Target Neighborhood Hits	446	Shared Neighborhood Hits	40
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

HIP1R_HUMAN
NC score	0.088105 (rank : 476)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	255	Target Neighborhood Hits	809	Shared Neighborhood Hits	105
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

RBNS5_MOUSE
NC score	0.088098 (rank : 477)	θ value	θ > 10 (rank : 745)
Query Neighborhood Hits	255	Target Neighborhood Hits	266	Shared Neighborhood Hits	47
SwissProt Accessions	Q80Y56, Q8K0L6, Q9CTW0	Gene names	Zfyve20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20).

KIF5A_MOUSE
NC score	0.087874 (rank : 478)	θ value	0.0961366 (rank : 113)
Query Neighborhood Hits	255	Target Neighborhood Hits	859	Shared Neighborhood Hits	116
SwissProt Accessions	P33175, Q5DTP1, Q6PDY7, Q9Z2F9	Gene names	Kif5a, Kiaa4086, Kif5, Nkhc1
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

RBNS5_HUMAN
NC score	0.087835 (rank : 479)	θ value	θ > 10 (rank : 744)
Query Neighborhood Hits	255	Target Neighborhood Hits	242	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H1K0, Q3KP30, Q59EY8, Q8NAQ1	Gene names	ZFYVE20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20) (110 kDa protein).

TPM1_MOUSE
NC score	0.087778 (rank : 480)	θ value	θ > 10 (rank : 863)
Query Neighborhood Hits	255	Target Neighborhood Hits	729	Shared Neighborhood Hits	102
SwissProt Accessions	P58771, P02558, P19354, P46902, P99034	Gene names	Tpm1, Tpm-1, Tpma
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

AKAP6_HUMAN
NC score	0.087761 (rank : 481)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	255	Target Neighborhood Hits	263	Shared Neighborhood Hits	56
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

CTGE5_HUMAN
NC score	0.087698 (rank : 482)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	255	Target Neighborhood Hits	800	Shared Neighborhood Hits	108
SwissProt Accessions	O15320, O00169, Q6P2R8, Q8IX92, Q8IX93	Gene names	CTAGE5, MEA11, MEA6, MGEA11, MGEA6
Domain Architecture
Description	Cutaneous T-cell lymphoma-associated antigen 5 (cTAGE-5 protein) (cTAGE family member 5) (Meningioma-expressed antigen 6/11).

RFIP4_HUMAN
NC score	0.087669 (rank : 483)	θ value	θ > 10 (rank : 751)
Query Neighborhood Hits	255	Target Neighborhood Hits	785	Shared Neighborhood Hits	103
SwissProt Accessions	Q86YS3, Q8N829, Q8NDT7, Q969D8	Gene names	RAB11FIP4, KIAA1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

LRRF2_MOUSE
NC score	0.087537 (rank : 484)	θ value	θ > 10 (rank : 587)
Query Neighborhood Hits	255	Target Neighborhood Hits	556	Shared Neighborhood Hits	88
SwissProt Accessions	Q91WK0, Q8BVD1, Q9CU89	Gene names	Lrrfip2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

MACOI_MOUSE
NC score	0.087240 (rank : 485)	θ value	θ > 10 (rank : 596)
Query Neighborhood Hits	255	Target Neighborhood Hits	620	Shared Neighborhood Hits	99
SwissProt Accessions	Q7TQE6	Gene names	Tmem57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57) (Brain-specific adaptor protein C61).

MACOI_HUMAN
NC score	0.087220 (rank : 486)	θ value	θ > 10 (rank : 595)
Query Neighborhood Hits	255	Target Neighborhood Hits	650	Shared Neighborhood Hits	97
SwissProt Accessions	Q8N5G2, Q2TLX5, Q2TLX6, Q9NVG6	Gene names	TMEM57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57).

PACN1_MOUSE
NC score	0.087192 (rank : 487)	θ value	θ > 10 (rank : 690)
Query Neighborhood Hits	255	Target Neighborhood Hits	283	Shared Neighborhood Hits	55
SwissProt Accessions	Q61644	Gene names	Pacsin1, Pacsin
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

HOME2_MOUSE
NC score	0.087153 (rank : 488)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	255	Target Neighborhood Hits	882	Shared Neighborhood Hits	103
SwissProt Accessions	Q9QWW1, O89025, Q9Z0E4	Gene names	Homer2, Vesl2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).

PHLB2_MOUSE
NC score	0.087044 (rank : 489)	θ value	θ > 10 (rank : 701)
Query Neighborhood Hits	255	Target Neighborhood Hits	1016	Shared Neighborhood Hits	111
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

TXLNA_MOUSE
NC score	0.087031 (rank : 490)	θ value	θ > 10 (rank : 881)
Query Neighborhood Hits	255	Target Neighborhood Hits	846	Shared Neighborhood Hits	107
SwissProt Accessions	Q6PAM1, Q6P1E5	Gene names	Txlna, Txln
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

BRE1B_MOUSE
NC score	0.086918 (rank : 491)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	255	Target Neighborhood Hits	970	Shared Neighborhood Hits	103
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

P85B_MOUSE
NC score	0.086864 (rank : 492)	θ value	θ > 10 (rank : 688)
Query Neighborhood Hits	255	Target Neighborhood Hits	519	Shared Neighborhood Hits	90
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

JIP3_HUMAN
NC score	0.086647 (rank : 493)	θ value	1.06291 (rank : 167)
Query Neighborhood Hits	255	Target Neighborhood Hits	1039	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

CF182_MOUSE
NC score	0.086535 (rank : 494)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	255	Target Neighborhood Hits	551	Shared Neighborhood Hits	87
SwissProt Accessions	Q8VDS7, Q9CZE0, Q9D5A1	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf182 homolog.

PHLB2_HUMAN
NC score	0.086481 (rank : 495)	θ value	θ > 10 (rank : 700)
Query Neighborhood Hits	255	Target Neighborhood Hits	964	Shared Neighborhood Hits	111
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

ANM2_MOUSE
NC score	0.086468 (rank : 496)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	255	Target Neighborhood Hits	175	Shared Neighborhood Hits	38
SwissProt Accessions	Q9R144	Gene names	Prmt2, Hrmt1l1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

RABE2_HUMAN
NC score	0.086433 (rank : 497)	θ value	θ > 10 (rank : 730)
Query Neighborhood Hits	255	Target Neighborhood Hits	545	Shared Neighborhood Hits	85
SwissProt Accessions	Q9H5N1	Gene names	RABEP2, RABPT5B
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

LIPB1_MOUSE
NC score	0.086329 (rank : 498)	θ value	θ > 10 (rank : 573)
Query Neighborhood Hits	255	Target Neighborhood Hits	727	Shared Neighborhood Hits	109
SwissProt Accessions	Q8C8U0, Q69ZN5, Q6GQV3, Q80VB4, Q9CUT7	Gene names	Ppfibp1, Kiaa1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1).

SNX23_HUMAN
NC score	0.086300 (rank : 499)	θ value	θ > 10 (rank : 806)
Query Neighborhood Hits	255	Target Neighborhood Hits	944	Shared Neighborhood Hits	114
SwissProt Accessions	Q96L93, Q5HYC0, Q5HYK1, Q5JWW3, Q5TFK5, Q86VL9, Q86YS5, Q8IYU0, Q9BQJ8, Q9BQM0, Q9BQM1, Q9BQM5, Q9H5U0, Q9HCI2, Q9NXN9	Gene names	C20orf23, KIAA1590, SNX23
Domain Architecture
Description	Kinesin-like motor protein C20orf23 (Sorting nexin-23).

KIF4A_MOUSE
NC score	0.086286 (rank : 500)	θ value	θ > 10 (rank : 549)
Query Neighborhood Hits	255	Target Neighborhood Hits	1033	Shared Neighborhood Hits	111
SwissProt Accessions	P33174	Gene names	Kif4a, Kif4, Kns4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

MYH14_HUMAN
NC score	0.086164 (rank : 501)	θ value	θ > 10 (rank : 633)
Query Neighborhood Hits	255	Target Neighborhood Hits	995	Shared Neighborhood Hits	109
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

FLNC_HUMAN
NC score	0.086154 (rank : 502)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	255	Target Neighborhood Hits	116	Shared Neighborhood Hits	25
SwissProt Accessions	Q14315, O95303, Q07985, Q9NS12, Q9NYE5, Q9UMR8, Q9Y503	Gene names	FLNC, ABPL, FLN2
Domain Architecture
Description	Filamin-C (Gamma-filamin) (Filamin-2) (Protein FLNc) (Actin-binding- like protein) (ABP-L) (ABP-280-like protein).

CCD93_HUMAN
NC score	0.085931 (rank : 503)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	255	Target Neighborhood Hits	600	Shared Neighborhood Hits	91
SwissProt Accessions	Q567U6, Q4LE78, Q53TJ2, Q8TBX5, Q9H6R5, Q9NV15	Gene names	CCDC93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

MMRN1_HUMAN
NC score	0.085895 (rank : 504)	θ value	θ > 10 (rank : 616)
Query Neighborhood Hits	255	Target Neighborhood Hits	636	Shared Neighborhood Hits	81
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

LASP1_HUMAN
NC score	0.085810 (rank : 505)	θ value	θ > 10 (rank : 564)
Query Neighborhood Hits	255	Target Neighborhood Hits	293	Shared Neighborhood Hits	44
SwissProt Accessions	Q14847, Q96ED2, Q96IG0	Gene names	LASP1, MLN50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

MICA2_HUMAN
NC score	0.085775 (rank : 506)	θ value	1.06291 (rank : 170)
Query Neighborhood Hits	255	Target Neighborhood Hits	174	Shared Neighborhood Hits	26
SwissProt Accessions	O94851, Q7Z3A8	Gene names	MICAL2, KIAA0750
Domain Architecture
Description	Protein MICAL-2.

PEX13_MOUSE
NC score	0.085641 (rank : 507)	θ value	θ > 10 (rank : 698)
Query Neighborhood Hits	255	Target Neighborhood Hits	126	Shared Neighborhood Hits	33
SwissProt Accessions	Q9D0K1, Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9EPK1	Gene names	Pex13
Domain Architecture	No domain graphic available
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

LIPB1_HUMAN
NC score	0.085640 (rank : 508)	θ value	θ > 10 (rank : 572)
Query Neighborhood Hits	255	Target Neighborhood Hits	640	Shared Neighborhood Hits	99
SwissProt Accessions	Q86W92, O75336, Q86X70, Q9NY03, Q9ULJ0	Gene names	PPFIBP1, KIAA1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2).

RFIP4_MOUSE
NC score	0.085193 (rank : 509)	θ value	θ > 10 (rank : 752)
Query Neighborhood Hits	255	Target Neighborhood Hits	708	Shared Neighborhood Hits	99
SwissProt Accessions	Q8BQP8, Q80T87	Gene names	Rab11fip4, Kiaa1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

CT096_HUMAN
NC score	0.085122 (rank : 510)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	255	Target Neighborhood Hits	438	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NUD7, Q8N840, Q8NAX5	Gene names	C20orf96
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf96.

TXLNG_MOUSE
NC score	0.085112 (rank : 511)	θ value	θ > 10 (rank : 884)
Query Neighborhood Hits	255	Target Neighborhood Hits	552	Shared Neighborhood Hits	90
SwissProt Accessions	Q8BHN1, Q8BP11	Gene names	Txlng
Domain Architecture	No domain graphic available
Description	Gamma-taxilin.

FLNB_MOUSE
NC score	0.085060 (rank : 512)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	255	Target Neighborhood Hits	126	Shared Neighborhood Hits	28
SwissProt Accessions	Q80X90, Q8VHX4, Q8VHX7, Q99KY3	Gene names	Flnb
Domain Architecture
Description	Filamin-B (FLN-B) (Beta-filamin) (Actin-binding-like protein) (ABP- 280-like protein).

NEBU_HUMAN
NC score	0.084925 (rank : 513)	θ value	θ > 10 (rank : 665)
Query Neighborhood Hits	255	Target Neighborhood Hits	420	Shared Neighborhood Hits	75
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

TNIP3_HUMAN
NC score	0.084890 (rank : 514)	θ value	θ > 10 (rank : 858)
Query Neighborhood Hits	255	Target Neighborhood Hits	511	Shared Neighborhood Hits	82
SwissProt Accessions	Q96KP6, Q96PQ3, Q9H780	Gene names	TNIP3, ABIN3, LIND
Domain Architecture	No domain graphic available
Description	TNFAIP3-interacting protein 3 (Listeria-induced gene protein) (A20- binding inhibitor of NF-kappa-B activation 3) (ABIN-3).

T3JAM_MOUSE
NC score	0.084836 (rank : 515)	θ value	θ > 10 (rank : 839)
Query Neighborhood Hits	255	Target Neighborhood Hits	535	Shared Neighborhood Hits	83
SwissProt Accessions	Q8C0G2, Q8BY50, Q8K1Y9	Gene names	Traf3ip3, T3jam
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

HGS_MOUSE
NC score	0.084644 (rank : 516)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	255	Target Neighborhood Hits	589	Shared Neighborhood Hits	48
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

VDP_HUMAN
NC score	0.084451 (rank : 517)	θ value	θ > 10 (rank : 890)
Query Neighborhood Hits	255	Target Neighborhood Hits	645	Shared Neighborhood Hits	93
SwissProt Accessions	O60763	Gene names	VDP
Domain Architecture
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

HGS_HUMAN
NC score	0.084374 (rank : 518)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	255	Target Neighborhood Hits	517	Shared Neighborhood Hits	50
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

LUZP1_HUMAN
NC score	0.084301 (rank : 519)	θ value	θ > 10 (rank : 588)
Query Neighborhood Hits	255	Target Neighborhood Hits	739	Shared Neighborhood Hits	94
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

FLNA_MOUSE
NC score	0.084258 (rank : 520)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	255	Target Neighborhood Hits	142	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BTM8, O54934, Q7TQI1, Q8BLK1, Q8BTN7, Q8VHX5, Q8VHX8, Q99KQ2	Gene names	Flna, Fln, Fln1
Domain Architecture
Description	Filamin-A (Alpha-filamin) (Filamin-1) (Endothelial actin-binding protein) (Actin-binding protein 280) (ABP-280) (Nonmuscle filamin).

FLNA_HUMAN
NC score	0.084127 (rank : 521)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	255	Target Neighborhood Hits	138	Shared Neighborhood Hits	28
SwissProt Accessions	P21333	Gene names	FLNA, FLN, FLN1
Domain Architecture
Description	Filamin-A (Alpha-filamin) (Filamin-1) (Endothelial actin-binding protein) (Actin-binding protein 280) (ABP-280) (Nonmuscle filamin).

LZTS1_HUMAN
NC score	0.084086 (rank : 522)	θ value	θ > 10 (rank : 590)
Query Neighborhood Hits	255	Target Neighborhood Hits	532	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Y250, Q9Y5V7, Q9Y5V8, Q9Y5V9, Q9Y5W0, Q9Y5W1, Q9Y5W2	Gene names	LZTS1, FEZ1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

FLNB_HUMAN
NC score	0.084065 (rank : 523)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	255	Target Neighborhood Hits	111	Shared Neighborhood Hits	28
SwissProt Accessions	O75369, Q13706, Q8WXS9, Q8WXT0, Q8WXT1, Q8WXT2, Q9NRB5, Q9NT26, Q9UEV9	Gene names	FLNB, FLN1L, FLN3, TABP, TAP
Domain Architecture
Description	Filamin-B (FLN-B) (Beta-filamin) (Actin-binding-like protein) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP) (ABP- 280 homolog) (ABP-278) (Filamin 3) (Filamin homolog 1) (Fh1).

RUFY3_MOUSE
NC score	0.083868 (rank : 524)	θ value	θ > 10 (rank : 772)
Query Neighborhood Hits	255	Target Neighborhood Hits	579	Shared Neighborhood Hits	97
SwissProt Accessions	Q9D394, Q3U348, Q3UF96, Q6PE64, Q8VD10	Gene names	Rufy3, D5Bwg0860e, Ripx
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

CT2NL_HUMAN
NC score	0.083820 (rank : 525)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	255	Target Neighborhood Hits	1059	Shared Neighborhood Hits	104
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

KI21A_HUMAN
NC score	0.083781 (rank : 526)	θ value	0.47712 (rank : 150)
Query Neighborhood Hits	255	Target Neighborhood Hits	1543	Shared Neighborhood Hits	115
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

MRCKB_HUMAN
NC score	0.083644 (rank : 527)	θ value	0.813845 (rank : 161)
Query Neighborhood Hits	255	Target Neighborhood Hits	2239	Shared Neighborhood Hits	152
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

LASP1_MOUSE
NC score	0.083637 (rank : 528)	θ value	θ > 10 (rank : 565)
Query Neighborhood Hits	255	Target Neighborhood Hits	297	Shared Neighborhood Hits	44
SwissProt Accessions	Q61792, Q62416	Gene names	Lasp1, Mln50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

MAP1A_HUMAN
NC score	0.083552 (rank : 529)	θ value	θ > 10 (rank : 597)
Query Neighborhood Hits	255	Target Neighborhood Hits	1626	Shared Neighborhood Hits	116
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

POF1B_HUMAN
NC score	0.083429 (rank : 530)	θ value	θ > 10 (rank : 723)
Query Neighborhood Hits	255	Target Neighborhood Hits	494	Shared Neighborhood Hits	87
SwissProt Accessions	Q8WVV4, Q5H9E9, Q5H9F0, Q8NG12, Q9H5Y2, Q9H738, Q9H744	Gene names	POF1B
Domain Architecture	No domain graphic available
Description	Protein POF1B (Premature ovarian failure protein 1B).

TEX9_HUMAN
NC score	0.083398 (rank : 531)	θ value	θ > 10 (rank : 855)
Query Neighborhood Hits	255	Target Neighborhood Hits	541	Shared Neighborhood Hits	89
SwissProt Accessions	Q8N6V9	Gene names	TEX9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein.

CA065_HUMAN
NC score	0.083372 (rank : 532)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	255	Target Neighborhood Hits	469	Shared Neighborhood Hits	77
SwissProt Accessions	Q8N715, Q8N746, Q8NA93	Gene names	C1orf65
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf65.

DLG5_HUMAN
NC score	0.083246 (rank : 533)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	255	Target Neighborhood Hits	1088	Shared Neighborhood Hits	117
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

CRCM_HUMAN
NC score	0.083234 (rank : 534)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	255	Target Neighborhood Hits	520	Shared Neighborhood Hits	86
SwissProt Accessions	P23508	Gene names	MCC
Domain Architecture
Description	Colorectal mutant cancer protein (Protein MCC).

TXLNB_MOUSE
NC score	0.083117 (rank : 535)	θ value	θ > 10 (rank : 882)
Query Neighborhood Hits	255	Target Neighborhood Hits	640	Shared Neighborhood Hits	93
SwissProt Accessions	Q8VBT1, Q3UVB8, Q8BUK2	Gene names	Txlnb, Mdp77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77).

TRAIP_HUMAN
NC score	0.083110 (rank : 536)	θ value	θ > 10 (rank : 871)
Query Neighborhood Hits	255	Target Neighborhood Hits	780	Shared Neighborhood Hits	94
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

RUFY3_HUMAN
NC score	0.082794 (rank : 537)	θ value	θ > 10 (rank : 771)
Query Neighborhood Hits	255	Target Neighborhood Hits	594	Shared Neighborhood Hits	97
SwissProt Accessions	Q7L099, O94948, Q9UI00	Gene names	RUFY3, KIAA0871
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

NDE1_HUMAN
NC score	0.082778 (rank : 538)	θ value	θ > 10 (rank : 657)
Query Neighborhood Hits	255	Target Neighborhood Hits	823	Shared Neighborhood Hits	102
SwissProt Accessions	Q9NXR1, Q49AQ2	Gene names	NDE1, NUDE
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE).

TACC2_HUMAN
NC score	0.082713 (rank : 539)	θ value	θ > 10 (rank : 842)
Query Neighborhood Hits	255	Target Neighborhood Hits	856	Shared Neighborhood Hits	101
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

CTRO_MOUSE
NC score	0.082431 (rank : 540)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	255	Target Neighborhood Hits	2344	Shared Neighborhood Hits	146
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

CAF1A_MOUSE
NC score	0.081753 (rank : 541)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	255	Target Neighborhood Hits	736	Shared Neighborhood Hits	92
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

P55G_HUMAN
NC score	0.081690 (rank : 542)	θ value	θ > 10 (rank : 683)
Query Neighborhood Hits	255	Target Neighborhood Hits	451	Shared Neighborhood Hits	82
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

TPM4_MOUSE
NC score	0.081612 (rank : 543)	θ value	θ > 10 (rank : 869)
Query Neighborhood Hits	255	Target Neighborhood Hits	703	Shared Neighborhood Hits	96
SwissProt Accessions	Q6IRU2	Gene names	Tpm4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4).

TPM4_HUMAN
NC score	0.081287 (rank : 544)	θ value	θ > 10 (rank : 868)
Query Neighborhood Hits	255	Target Neighborhood Hits	525	Shared Neighborhood Hits	85
SwissProt Accessions	P67936, P07226, Q15659, Q9BU85, Q9H8Q3	Gene names	TPM4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4) (TM30p1).

KI21A_MOUSE
NC score	0.081133 (rank : 545)	θ value	1.81305 (rank : 184)
Query Neighborhood Hits	255	Target Neighborhood Hits	1317	Shared Neighborhood Hits	112
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

CAR11_HUMAN
NC score	0.080955 (rank : 546)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	255	Target Neighborhood Hits	690	Shared Neighborhood Hits	96
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

P55G_MOUSE
NC score	0.080901 (rank : 547)	θ value	θ > 10 (rank : 684)
Query Neighborhood Hits	255	Target Neighborhood Hits	401	Shared Neighborhood Hits	81
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

TRAIP_MOUSE
NC score	0.080849 (rank : 548)	θ value	θ > 10 (rank : 872)
Query Neighborhood Hits	255	Target Neighborhood Hits	745	Shared Neighborhood Hits	93
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

MRCKB_MOUSE
NC score	0.080670 (rank : 549)	θ value	θ > 10 (rank : 622)
Query Neighborhood Hits	255	Target Neighborhood Hits	2180	Shared Neighborhood Hits	154
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

TXLNA_HUMAN
NC score	0.080513 (rank : 550)	θ value	θ > 10 (rank : 880)
Query Neighborhood Hits	255	Target Neighborhood Hits	982	Shared Neighborhood Hits	101
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

TXLNB_HUMAN
NC score	0.080212 (rank : 551)	θ value	4.03905 (rank : 212)
Query Neighborhood Hits	255	Target Neighborhood Hits	912	Shared Neighborhood Hits	93
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

CLC4F_HUMAN
NC score	0.080085 (rank : 552)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	255	Target Neighborhood Hits	513	Shared Neighborhood Hits	83
SwissProt Accessions	Q8N1N0	Gene names	CLEC4F, CLECSF13
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member F (C-type lectin superfamily member 13) (C-type lectin 13).

WDR67_HUMAN
NC score	0.080051 (rank : 553)	θ value	θ > 10 (rank : 897)
Query Neighborhood Hits	255	Target Neighborhood Hits	782	Shared Neighborhood Hits	94
SwissProt Accessions	Q96DN5, Q3MIR6, Q8TBP9	Gene names	WDR67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67.

K0552_HUMAN
NC score	0.079989 (rank : 554)	θ value	θ > 10 (rank : 537)
Query Neighborhood Hits	255	Target Neighborhood Hits	442	Shared Neighborhood Hits	79
SwissProt Accessions	O60299	Gene names	KIAA0552
Domain Architecture
Description	Protein KIAA0552.

MYO5C_HUMAN
NC score	0.079956 (rank : 555)	θ value	6.88961 (rank : 234)
Query Neighborhood Hits	255	Target Neighborhood Hits	1206	Shared Neighborhood Hits	124
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

FNBP2_HUMAN
NC score	0.079860 (rank : 556)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	255	Target Neighborhood Hits	432	Shared Neighborhood Hits	76
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

POF1B_MOUSE
NC score	0.079808 (rank : 557)	θ value	θ > 10 (rank : 724)
Query Neighborhood Hits	255	Target Neighborhood Hits	530	Shared Neighborhood Hits	86
SwissProt Accessions	Q8K4L4, Q8C3A2	Gene names	Pof1b
Domain Architecture	No domain graphic available
Description	Protein POF1B.

CEP70_HUMAN
NC score	0.079180 (rank : 558)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	255	Target Neighborhood Hits	432	Shared Neighborhood Hits	79
SwissProt Accessions	Q8NHQ1, Q96B31, Q9H2C3, Q9H2Z1, Q9H940	Gene names	CEP70, BITE
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 70 kDa (Cep70 protein) (p10-binding protein).

CT2NL_MOUSE
NC score	0.079148 (rank : 559)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	255	Target Neighborhood Hits	902	Shared Neighborhood Hits	98
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

MOES_MOUSE
NC score	0.078964 (rank : 560)	θ value	θ > 10 (rank : 619)
Query Neighborhood Hits	255	Target Neighborhood Hits	923	Shared Neighborhood Hits	108
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

CF152_HUMAN
NC score	0.078578 (rank : 561)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	255	Target Neighborhood Hits	704	Shared Neighborhood Hits	95
SwissProt Accessions	Q86VQ0, Q9BWX7	Gene names	C6orf152
Domain Architecture	No domain graphic available
Description	Protein C6orf152.

MICA3_MOUSE
NC score	0.078465 (rank : 562)	θ value	θ > 10 (rank : 611)
Query Neighborhood Hits	255	Target Neighborhood Hits	104	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CJ19, Q80TE8, Q8BXB1	Gene names	Mical3, Kiaa1364
Domain Architecture
Description	Protein MICAL-3.

MRCKA_HUMAN
NC score	0.078406 (rank : 563)	θ value	0.47712 (rank : 151)
Query Neighborhood Hits	255	Target Neighborhood Hits	1999	Shared Neighborhood Hits	147
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

HAP1_HUMAN
NC score	0.078301 (rank : 564)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	255	Target Neighborhood Hits	606	Shared Neighborhood Hits	96
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

RAI14_MOUSE
NC score	0.078233 (rank : 565)	θ value	θ > 10 (rank : 737)
Query Neighborhood Hits	255	Target Neighborhood Hits	1505	Shared Neighborhood Hits	124
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

APOE_MOUSE
NC score	0.078077 (rank : 566)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	255	Target Neighborhood Hits	319	Shared Neighborhood Hits	68
SwissProt Accessions	P08226	Gene names	Apoe
Domain Architecture
Description	Apolipoprotein E precursor (Apo-E).

NEB2_MOUSE
NC score	0.077918 (rank : 567)	θ value	θ > 10 (rank : 663)
Query Neighborhood Hits	255	Target Neighborhood Hits	889	Shared Neighborhood Hits	104
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEST_HUMAN
NC score	0.077835 (rank : 568)	θ value	θ > 10 (rank : 667)
Query Neighborhood Hits	255	Target Neighborhood Hits	1305	Shared Neighborhood Hits	113
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

MOES_HUMAN
NC score	0.077814 (rank : 569)	θ value	θ > 10 (rank : 618)
Query Neighborhood Hits	255	Target Neighborhood Hits	892	Shared Neighborhood Hits	107
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

RIMB2_MOUSE
NC score	0.077726 (rank : 570)	θ value	θ > 10 (rank : 758)
Query Neighborhood Hits	255	Target Neighborhood Hits	246	Shared Neighborhood Hits	43
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

LZTS1_MOUSE
NC score	0.077445 (rank : 571)	θ value	θ > 10 (rank : 591)
Query Neighborhood Hits	255	Target Neighborhood Hits	540	Shared Neighborhood Hits	86
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

TXLNG_HUMAN
NC score	0.077352 (rank : 572)	θ value	θ > 10 (rank : 883)
Query Neighborhood Hits	255	Target Neighborhood Hits	568	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NUQ3, Q9P0X1	Gene names	TXLNG, CXorf15, LSR5
Domain Architecture	No domain graphic available
Description	Gamma-taxilin (Lipopolysaccharide-specific response protein 5).

CTRO_HUMAN
NC score	0.077139 (rank : 573)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	255	Target Neighborhood Hits	2092	Shared Neighborhood Hits	146
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

CEP57_HUMAN
NC score	0.077135 (rank : 574)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	255	Target Neighborhood Hits	576	Shared Neighborhood Hits	93
SwissProt Accessions	Q86XR8, Q14704, Q8IXP0, Q9BVF9	Gene names	CEP57, KIAA0092, TSP57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin) (FGF2-interacting protein).

MICA2_MOUSE
NC score	0.076985 (rank : 575)	θ value	θ > 10 (rank : 609)
Query Neighborhood Hits	255	Target Neighborhood Hits	144	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BML1, Q3UPU6	Gene names	Mical2
Domain Architecture
Description	Protein MICAL-2.

LRSM1_HUMAN
NC score	0.076736 (rank : 576)	θ value	0.0736092 (rank : 110)
Query Neighborhood Hits	255	Target Neighborhood Hits	1078	Shared Neighborhood Hits	110
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

AMOL2_HUMAN
NC score	0.076706 (rank : 577)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	255	Target Neighborhood Hits	603	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Y2J4, Q53EP1, Q96F99, Q9UKB4	Gene names	AMOTL2, KIAA0989
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP).

ROCK1_MOUSE
NC score	0.076377 (rank : 578)	θ value	θ > 10 (rank : 761)
Query Neighborhood Hits	255	Target Neighborhood Hits	2126	Shared Neighborhood Hits	135
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

MMRN2_HUMAN
NC score	0.076335 (rank : 579)	θ value	θ > 10 (rank : 617)
Query Neighborhood Hits	255	Target Neighborhood Hits	400	Shared Neighborhood Hits	77
SwissProt Accessions	Q9H8L6, Q6P2N2	Gene names	MMRN2, EMILIN3
Domain Architecture
Description	Multimerin-2 precursor (EMILIN-3) (Elastin microfibril interface located protein 3) (Elastin microfibril interfacer 3) (EndoGlyx-1 p125/p140 subunit).

TACC3_MOUSE
NC score	0.076319 (rank : 580)	θ value	θ > 10 (rank : 845)
Query Neighborhood Hits	255	Target Neighborhood Hits	607	Shared Neighborhood Hits	89
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

TACC2_MOUSE
NC score	0.076288 (rank : 581)	θ value	θ > 10 (rank : 843)
Query Neighborhood Hits	255	Target Neighborhood Hits	774	Shared Neighborhood Hits	104
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

ROCK2_MOUSE
NC score	0.076175 (rank : 582)	θ value	θ > 10 (rank : 762)
Query Neighborhood Hits	255	Target Neighborhood Hits	2072	Shared Neighborhood Hits	145
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

CAF1A_HUMAN
NC score	0.076006 (rank : 583)	θ value	3.0926 (rank : 195)
Query Neighborhood Hits	255	Target Neighborhood Hits	750	Shared Neighborhood Hits	85
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CEP70_MOUSE
NC score	0.075960 (rank : 584)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	255	Target Neighborhood Hits	532	Shared Neighborhood Hits	82
SwissProt Accessions	Q6IQY5, Q9CRL9, Q9CTS4, Q9JIC1	Gene names	Cep70
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 70 kDa (Cep70 protein).

MICA3_HUMAN
NC score	0.075959 (rank : 585)	θ value	θ > 10 (rank : 610)
Query Neighborhood Hits	255	Target Neighborhood Hits	160	Shared Neighborhood Hits	24
SwissProt Accessions	Q7RTP6, Q6ICK4, Q9P2I3	Gene names	MICAL3, KIAA1364
Domain Architecture
Description	Protein MICAL-3.

P85A_HUMAN
NC score	0.075807 (rank : 586)	θ value	θ > 10 (rank : 685)
Query Neighborhood Hits	255	Target Neighborhood Hits	479	Shared Neighborhood Hits	78
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

ADIP_HUMAN
NC score	0.075645 (rank : 587)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	255	Target Neighborhood Hits	470	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y2D8, Q6P2P8, Q6ULS1, Q7L168, Q9UIX0	Gene names	SSX2IP, KIAA0923
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein) (SSX2-interacting protein).

CENPJ_HUMAN
NC score	0.075636 (rank : 588)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	255	Target Neighborhood Hits	721	Shared Neighborhood Hits	92
SwissProt Accessions	Q9HC77, Q5T6R5, Q96KS5, Q9C067	Gene names	CENPJ, CPAP, LAP, LIP1
Domain Architecture	No domain graphic available
Description	Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1).

NEB2_HUMAN
NC score	0.075588 (rank : 589)	θ value	θ > 10 (rank : 662)
Query Neighborhood Hits	255	Target Neighborhood Hits	883	Shared Neighborhood Hits	103
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

MORC3_HUMAN
NC score	0.075569 (rank : 590)	θ value	θ > 10 (rank : 620)
Query Neighborhood Hits	255	Target Neighborhood Hits	489	Shared Neighborhood Hits	96
SwissProt Accessions	Q14149, Q9UEZ2	Gene names	MORC3, KIAA0136, ZCWCC3
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 3 (Zinc finger CW-type coiled- coil domain protein 3).

KIF11_HUMAN
NC score	0.075459 (rank : 591)	θ value	θ > 10 (rank : 540)
Query Neighborhood Hits	255	Target Neighborhood Hits	583	Shared Neighborhood Hits	100
SwissProt Accessions	P52732, Q15716, Q5VWX0	Gene names	KIF11, EG5, KNSL1
Domain Architecture
Description	Kinesin-like protein KIF11 (Kinesin-related motor protein Eg5) (Kinesin-like spindle protein HKSP) (Thyroid receptor-interacting protein 5) (TRIP5) (Kinesin-like protein 1).

SKIL_MOUSE
NC score	0.075123 (rank : 592)	θ value	θ > 10 (rank : 792)
Query Neighborhood Hits	255	Target Neighborhood Hits	719	Shared Neighborhood Hits	100
SwissProt Accessions	Q60665, Q60702, Q78E90, Q80VK5	Gene names	Skil, Skir, Sno
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

OLR1_MOUSE
NC score	0.075074 (rank : 593)	θ value	6.88961 (rank : 235)
Query Neighborhood Hits	255	Target Neighborhood Hits	596	Shared Neighborhood Hits	82
SwissProt Accessions	Q9EQ09	Gene names	Olr1, Lox1
Domain Architecture	No domain graphic available
Description	Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) (Lectin-type oxidized LDL receptor 1) (Lectin-like oxidized LDL receptor 1) (Lectin-like oxLDL receptor 1) (LOX-1) [Contains: Oxidized low-density lipoprotein receptor 1, soluble form].

LIPB2_MOUSE
NC score	0.074984 (rank : 594)	θ value	θ > 10 (rank : 575)
Query Neighborhood Hits	255	Target Neighborhood Hits	570	Shared Neighborhood Hits	86
SwissProt Accessions	O35711, Q7TMG4, Q8CBS6, Q99KX6	Gene names	Ppfibp2, Cclp1
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2) (Coiled-coil-like protein 1).

SRGP2_MOUSE
NC score	0.074961 (rank : 595)	θ value	θ > 10 (rank : 820)
Query Neighborhood Hits	255	Target Neighborhood Hits	324	Shared Neighborhood Hits	65
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

TEKT1_MOUSE
NC score	0.074948 (rank : 596)	θ value	θ > 10 (rank : 854)
Query Neighborhood Hits	255	Target Neighborhood Hits	399	Shared Neighborhood Hits	79
SwissProt Accessions	Q9DAJ2	Gene names	Tekt1
Domain Architecture
Description	Tektin-1.

CF182_HUMAN
NC score	0.074847 (rank : 597)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	255	Target Neighborhood Hits	474	Shared Neighborhood Hits	80
SwissProt Accessions	Q8IYX8	Gene names	C6orf182
Domain Architecture	No domain graphic available
Description	Protein C6orf182.

RBM25_HUMAN
NC score	0.074272 (rank : 598)	θ value	θ > 10 (rank : 743)
Query Neighborhood Hits	255	Target Neighborhood Hits	682	Shared Neighborhood Hits	87
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

ROCK2_HUMAN
NC score	0.074177 (rank : 599)	θ value	5.27518 (rank : 226)
Query Neighborhood Hits	255	Target Neighborhood Hits	2073	Shared Neighborhood Hits	144
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

LZTS2_MOUSE
NC score	0.074099 (rank : 600)	θ value	θ > 10 (rank : 593)
Query Neighborhood Hits	255	Target Neighborhood Hits	423	Shared Neighborhood Hits	78
SwissProt Accessions	Q91YU6, Q569X6	Gene names	Lzts2, Kiaa1813
Domain Architecture
Description	Leucine zipper putative tumor suppressor 2.

CTGE2_HUMAN
NC score	0.073932 (rank : 601)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	255	Target Neighborhood Hits	594	Shared Neighborhood Hits	93
SwissProt Accessions	Q96RT6	Gene names	CTAGE1, CTAGE2
Domain Architecture	No domain graphic available
Description	Protein cTAGE-2.

LETM1_HUMAN
NC score	0.073926 (rank : 602)	θ value	θ > 10 (rank : 568)
Query Neighborhood Hits	255	Target Neighborhood Hits	338	Shared Neighborhood Hits	73
SwissProt Accessions	O95202, Q9UF65	Gene names	LETM1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

RAI14_HUMAN
NC score	0.073848 (rank : 603)	θ value	θ > 10 (rank : 736)
Query Neighborhood Hits	255	Target Neighborhood Hits	1367	Shared Neighborhood Hits	118
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

CCD42_HUMAN
NC score	0.073830 (rank : 604)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	255	Target Neighborhood Hits	406	Shared Neighborhood Hits	82
SwissProt Accessions	Q96M95, Q8N6Q0	Gene names	CCDC42
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 42.

TCGAP_MOUSE
NC score	0.073763 (rank : 605)	θ value	θ > 10 (rank : 850)
Query Neighborhood Hits	255	Target Neighborhood Hits	409	Shared Neighborhood Hits	44
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TACC1_MOUSE
NC score	0.073680 (rank : 606)	θ value	θ > 10 (rank : 841)
Query Neighborhood Hits	255	Target Neighborhood Hits	667	Shared Neighborhood Hits	95
SwissProt Accessions	Q6Y685, Q6Y686	Gene names	Tacc1
Domain Architecture	No domain graphic available
Description	Transforming acidic coiled-coil-containing protein 1.

SRGP1_HUMAN
NC score	0.073673 (rank : 607)	θ value	θ > 10 (rank : 818)
Query Neighborhood Hits	255	Target Neighborhood Hits	390	Shared Neighborhood Hits	72
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

APOA4_HUMAN
NC score	0.073670 (rank : 608)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	255	Target Neighborhood Hits	399	Shared Neighborhood Hits	78
SwissProt Accessions	P06727, Q6Q787	Gene names	APOA4
Domain Architecture
Description	Apolipoprotein A-IV precursor (Apo-AIV) (ApoA-IV).

SRGP2_HUMAN
NC score	0.073472 (rank : 609)	θ value	θ > 10 (rank : 819)
Query Neighborhood Hits	255	Target Neighborhood Hits	331	Shared Neighborhood Hits	64
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

CU013_HUMAN
NC score	0.073434 (rank : 610)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	255	Target Neighborhood Hits	405	Shared Neighborhood Hits	75
SwissProt Accessions	O95447	Gene names	C21orf13
Domain Architecture
Description	Protein C21orf13.

AMOL2_MOUSE
NC score	0.073278 (rank : 611)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	255	Target Neighborhood Hits	591	Shared Neighborhood Hits	95
SwissProt Accessions	Q8K371, Q3TPM1, Q7TPE4, Q8BP84, Q8BS08, Q9QUS0	Gene names	Amotl2
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2.

CENPH_HUMAN
NC score	0.073267 (rank : 612)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	255	Target Neighborhood Hits	335	Shared Neighborhood Hits	71
SwissProt Accessions	Q9H3R5	Gene names	CENPH, ICEN35
Domain Architecture	No domain graphic available
Description	Centromere protein H (CENP-H) (Interphase centromere complex protein 35).

IASPP_MOUSE
NC score	0.073124 (rank : 613)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	255	Target Neighborhood Hits	1024	Shared Neighborhood Hits	54
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

CTGE6_HUMAN
NC score	0.073070 (rank : 614)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	255	Target Neighborhood Hits	650	Shared Neighborhood Hits	90
SwissProt Accessions	Q86UF2	Gene names	CTAGE6
Domain Architecture	No domain graphic available
Description	Protein cTAGE-6 (cTAGE family member 6).

SHAN1_HUMAN
NC score	0.072958 (rank : 615)	θ value	θ > 10 (rank : 787)
Query Neighborhood Hits	255	Target Neighborhood Hits	1041	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

AL2SB_HUMAN
NC score	0.072746 (rank : 616)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	255	Target Neighborhood Hits	294	Shared Neighborhood Hits	66
SwissProt Accessions	Q96Q35	Gene names	ALS2CR12
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein.

CCD42_MOUSE
NC score	0.072734 (rank : 617)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	255	Target Neighborhood Hits	284	Shared Neighborhood Hits	77
SwissProt Accessions	Q5SV66, Q8BNY1	Gene names	Ccdc42
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 42.

RIMB2_HUMAN
NC score	0.072622 (rank : 618)	θ value	θ > 10 (rank : 757)
Query Neighborhood Hits	255	Target Neighborhood Hits	263	Shared Neighborhood Hits	37
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

COVA1_MOUSE
NC score	0.072462 (rank : 619)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	255	Target Neighborhood Hits	335	Shared Neighborhood Hits	60
SwissProt Accessions	Q8R0Z2, Q8BY59, Q8R372	Gene names	Cova1
Domain Architecture	No domain graphic available
Description	Tumor-associated hydroquinone oxidase (tNOX) (Cytosolic ovarian carcinoma antigen 1) (APK1 antigen) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)].

LIPB2_HUMAN
NC score	0.072233 (rank : 620)	θ value	θ > 10 (rank : 574)
Query Neighborhood Hits	255	Target Neighborhood Hits	599	Shared Neighborhood Hits	89
SwissProt Accessions	Q8ND30, O75337, Q8WW26	Gene names	PPFIBP2
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2).

LZTS2_HUMAN
NC score	0.072176 (rank : 621)	θ value	θ > 10 (rank : 592)
Query Neighborhood Hits	255	Target Neighborhood Hits	427	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BRK4, Q8N3I0, Q96J79, Q96JL2	Gene names	LZTS2, KIAA1813, LAPSER1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 2 (Protein LAPSER1).

CCD45_MOUSE
NC score	0.072153 (rank : 622)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	255	Target Neighborhood Hits	663	Shared Neighborhood Hits	85
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

AN30A_HUMAN
NC score	0.071870 (rank : 623)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	255	Target Neighborhood Hits	1119	Shared Neighborhood Hits	109
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

BI2L1_MOUSE
NC score	0.071711 (rank : 624)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	255	Target Neighborhood Hits	197	Shared Neighborhood Hits	36
SwissProt Accessions	Q9DBJ3	Gene names	Baiap2l1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

SEC20_MOUSE
NC score	0.071416 (rank : 625)	θ value	θ > 10 (rank : 778)
Query Neighborhood Hits	255	Target Neighborhood Hits	323	Shared Neighborhood Hits	71
SwissProt Accessions	Q6QD59, Q5M9M2	Gene names	Bnip1, Sec20, Sec20l
Domain Architecture	No domain graphic available
Description	Vesicle transport protein SEC20.

CCD93_MOUSE
NC score	0.071323 (rank : 626)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	255	Target Neighborhood Hits	362	Shared Neighborhood Hits	74
SwissProt Accessions	Q7TQK5, Q3TX53	Gene names	Ccdc93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

HOME1_MOUSE
NC score	0.071264 (rank : 627)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	255	Target Neighborhood Hits	630	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Z2Y3, Q8K3E1, Q8K4M8, Q9Z0E9, Q9Z216	Gene names	Homer1, Vesl1
Domain Architecture
Description	Homer protein homolog 1 (VASP/Ena-related gene up-regulated during seizure and LTP) (Vesl-1).

ROCK1_HUMAN
NC score	0.071244 (rank : 628)	θ value	θ > 10 (rank : 760)
Query Neighborhood Hits	255	Target Neighborhood Hits	2000	Shared Neighborhood Hits	132
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

IF2P_HUMAN
NC score	0.070885 (rank : 629)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	255	Target Neighborhood Hits	889	Shared Neighborhood Hits	85
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

GP73_MOUSE
NC score	0.070848 (rank : 630)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	255	Target Neighborhood Hits	506	Shared Neighborhood Hits	71
SwissProt Accessions	Q91XA2	Gene names	Golph2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

RASF8_HUMAN
NC score	0.070636 (rank : 631)	θ value	θ > 10 (rank : 738)
Query Neighborhood Hits	255	Target Neighborhood Hits	469	Shared Neighborhood Hits	77
SwissProt Accessions	Q8NHQ8, O95647, Q5SCI2, Q76KB6	Gene names	RASSF8, C12orf2
Domain Architecture
Description	Ras association domain-containing protein 8 (Carcinoma-associated protein HOJ-1).

MICA1_HUMAN
NC score	0.070611 (rank : 632)	θ value	θ > 10 (rank : 607)
Query Neighborhood Hits	255	Target Neighborhood Hits	279	Shared Neighborhood Hits	47
SwissProt Accessions	Q8TDZ2, Q7Z633, Q8IVS9, Q96G47, Q9H6X6, Q9H7I0, Q9HAA1, Q9UFF7	Gene names	MICAL1, MICAL, NICAL
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

IMMT_HUMAN
NC score	0.070601 (rank : 633)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	255	Target Neighborhood Hits	494	Shared Neighborhood Hits	86
SwissProt Accessions	Q16891, Q14539, Q15092, Q68D41, Q69HW5, Q6IBL0, Q7Z3X1, Q8TAJ5, Q9P0V2	Gene names	IMMT, HMP, PIG4
Domain Architecture	No domain graphic available
Description	Mitochondrial inner membrane protein (Mitofilin) (p87/89) (Proliferation-inducing gene 4 protein).

MYO1F_MOUSE
NC score	0.070391 (rank : 634)	θ value	θ > 10 (rank : 646)
Query Neighborhood Hits	255	Target Neighborhood Hits	262	Shared Neighborhood Hits	54
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

ZFY19_HUMAN
NC score	0.070349 (rank : 635)	θ value	θ > 10 (rank : 905)
Query Neighborhood Hits	255	Target Neighborhood Hits	206	Shared Neighborhood Hits	27
SwissProt Accessions	Q96K21, Q86WC2, Q8WU96	Gene names	ZFYVE19, MPFYVE
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19 (MLL partner containing FYVE domain).

CENPK_HUMAN
NC score	0.070160 (rank : 636)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	255	Target Neighborhood Hits	273	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BS16, Q9H4L0	Gene names	CENPK, ICEN37
Domain Architecture	No domain graphic available
Description	Centromere protein K (CENP-K) (Interphase centromere complex protein 37) (Protein AF-5alpha) (p33).

APOA4_MOUSE
NC score	0.069934 (rank : 637)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	255	Target Neighborhood Hits	435	Shared Neighborhood Hits	73
SwissProt Accessions	P06728	Gene names	Apoa4
Domain Architecture
Description	Apolipoprotein A-IV precursor (Apo-AIV) (ApoA-IV).

P85A_MOUSE
NC score	0.069763 (rank : 638)	θ value	θ > 10 (rank : 686)
Query Neighborhood Hits	255	Target Neighborhood Hits	435	Shared Neighborhood Hits	67
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

CI009_HUMAN
NC score	0.069631 (rank : 639)	θ value	0.0431538 (rank : 95)
Query Neighborhood Hits	255	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q96E40, Q9UGQ0	Gene names	C9orf9
Domain Architecture	No domain graphic available
Description	Protein C9orf9.

CEP57_MOUSE
NC score	0.069554 (rank : 640)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	255	Target Neighborhood Hits	580	Shared Neighborhood Hits	88
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

STIM1_HUMAN
NC score	0.069550 (rank : 641)	θ value	θ > 10 (rank : 829)
Query Neighborhood Hits	255	Target Neighborhood Hits	665	Shared Neighborhood Hits	93
SwissProt Accessions	Q13586	Gene names	STIM1, GOK
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

PININ_HUMAN
NC score	0.069549 (rank : 642)	θ value	θ > 10 (rank : 704)
Query Neighborhood Hits	255	Target Neighborhood Hits	753	Shared Neighborhood Hits	87
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

MRIP_HUMAN
NC score	0.069332 (rank : 643)	θ value	θ > 10 (rank : 625)
Query Neighborhood Hits	255	Target Neighborhood Hits	578	Shared Neighborhood Hits	82
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

MYO1F_HUMAN
NC score	0.069237 (rank : 644)	θ value	θ > 10 (rank : 645)
Query Neighborhood Hits	255	Target Neighborhood Hits	275	Shared Neighborhood Hits	54
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

IASPP_HUMAN
NC score	0.069196 (rank : 645)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	255	Target Neighborhood Hits	688	Shared Neighborhood Hits	47
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

NDE1_MOUSE
NC score	0.069037 (rank : 646)	θ value	θ > 10 (rank : 658)
Query Neighborhood Hits	255	Target Neighborhood Hits	602	Shared Neighborhood Hits	88
SwissProt Accessions	Q9CZA6, Q3UBS6, Q3UIC1, Q9ERR0	Gene names	Nde1, Nude
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE) (mNudE).

HC127_HUMAN
NC score	0.068971 (rank : 647)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	255	Target Neighborhood Hits	292	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NQZ6, Q5JTF9, Q9H9C3, Q9H9H7, Q9ULQ4	Gene names	HCA127, KIAA1166
Domain Architecture	No domain graphic available
Description	Hepatocellular carcinoma-associated antigen 127.

HC127_MOUSE
NC score	0.068971 (rank : 648)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	255	Target Neighborhood Hits	292	Shared Neighborhood Hits	63
SwissProt Accessions	Q68FG0, Q6ZPW6	Gene names	Hca127, Kiaa1166
Domain Architecture	No domain graphic available
Description	Hepatocellular carcinoma-associated antigen 127 homolog.

CAR10_HUMAN
NC score	0.068939 (rank : 649)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	255	Target Neighborhood Hits	569	Shared Neighborhood Hits	88
SwissProt Accessions	Q9BWT7, Q14CQ8, Q5TFG6, Q9UGR5, Q9UGR6, Q9Y3H0	Gene names	CARD10, CARMA3
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3).

MRIP_MOUSE
NC score	0.068712 (rank : 650)	θ value	θ > 10 (rank : 626)
Query Neighborhood Hits	255	Target Neighborhood Hits	569	Shared Neighborhood Hits	82
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

CF152_MOUSE
NC score	0.068705 (rank : 651)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	255	Target Neighborhood Hits	597	Shared Neighborhood Hits	84
SwissProt Accessions	Q80ST9, Q9CYM9, Q9D5J9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf152 homolog.

TACC1_HUMAN
NC score	0.068389 (rank : 652)	θ value	θ > 10 (rank : 840)
Query Neighborhood Hits	255	Target Neighborhood Hits	597	Shared Neighborhood Hits	92
SwissProt Accessions	O75410, Q6Y687, Q86YG7, Q8IUJ2, Q8IUJ3, Q8IUJ4, Q8IZG2, Q8NEY7, Q9UPP9	Gene names	TACC1, KIAA1103
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 1 (Taxin 1) (Gastric cancer antigen Ga55).

KI21B_HUMAN
NC score	0.068267 (rank : 653)	θ value	0.62314 (rank : 154)
Query Neighborhood Hits	255	Target Neighborhood Hits	1017	Shared Neighborhood Hits	104
SwissProt Accessions	O75037, Q5T4J3	Gene names	KIF21B, KIAA0449
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B.

MYO1E_HUMAN
NC score	0.068254 (rank : 654)	θ value	θ > 10 (rank : 644)
Query Neighborhood Hits	255	Target Neighborhood Hits	293	Shared Neighborhood Hits	55
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

STXB4_HUMAN
NC score	0.067885 (rank : 655)	θ value	θ > 10 (rank : 833)
Query Neighborhood Hits	255	Target Neighborhood Hits	616	Shared Neighborhood Hits	91
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

LBN_MOUSE
NC score	0.067745 (rank : 656)	θ value	θ > 10 (rank : 567)
Query Neighborhood Hits	255	Target Neighborhood Hits	310	Shared Neighborhood Hits	74
SwissProt Accessions	Q8K1G2, Q8BRF3	Gene names	Evc2, Lbn
Domain Architecture	No domain graphic available
Description	Limbin.

TTC3_HUMAN
NC score	0.067629 (rank : 657)	θ value	θ > 10 (rank : 878)
Query Neighborhood Hits	255	Target Neighborhood Hits	664	Shared Neighborhood Hits	84
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

KI21B_MOUSE
NC score	0.067610 (rank : 658)	θ value	0.62314 (rank : 155)
Query Neighborhood Hits	255	Target Neighborhood Hits	997	Shared Neighborhood Hits	100
SwissProt Accessions	Q9QXL1, P97424	Gene names	Kif21b, Kif6
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B (Kinesin-like protein KIF6).

ENAH_HUMAN
NC score	0.067604 (rank : 659)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	255	Target Neighborhood Hits	784	Shared Neighborhood Hits	90
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

PHLB1_HUMAN
NC score	0.067535 (rank : 660)	θ value	θ > 10 (rank : 699)
Query Neighborhood Hits	255	Target Neighborhood Hits	1038	Shared Neighborhood Hits	105
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

FYV1_HUMAN
NC score	0.067415 (rank : 661)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	255	Target Neighborhood Hits	217	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

STIM1_MOUSE
NC score	0.067414 (rank : 662)	θ value	θ > 10 (rank : 830)
Query Neighborhood Hits	255	Target Neighborhood Hits	660	Shared Neighborhood Hits	92
SwissProt Accessions	P70302	Gene names	Stim1, Sim
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

HOME2_HUMAN
NC score	0.067407 (rank : 663)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	255	Target Neighborhood Hits	532	Shared Neighborhood Hits	79
SwissProt Accessions	Q9NSB8, O95269, O95349, Q9NSB6, Q9NSB7, Q9UNT7	Gene names	HOMER2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin).

COVA1_HUMAN
NC score	0.067353 (rank : 664)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	255	Target Neighborhood Hits	416	Shared Neighborhood Hits	76
SwissProt Accessions	Q16206, Q5VTJ1, Q5VTJ2, Q8WUX0, Q9NTP6, Q9UH82	Gene names	COVA1
Domain Architecture
Description	Tumor-associated hydroquinone oxidase (tNOX) (Cytosolic ovarian carcinoma antigen 1) (APK1 antigen) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)].

JIP4_HUMAN
NC score	0.067116 (rank : 665)	θ value	θ > 10 (rank : 533)
Query Neighborhood Hits	255	Target Neighborhood Hits	585	Shared Neighborhood Hits	78
SwissProt Accessions	O60271, O60905, Q3KQU8, Q3MKM7, Q86WC7, Q86WC8, Q8IZX7, Q96II0, Q9H811	Gene names	SPAG9, HSS, KIAA0516, MAPK8IP4, SYD1
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (Human lung cancer protein 6) (HLC-6) (Proliferation-inducing protein 6) (Sperm-specific protein) (Sperm surface protein) (Protein highly expressed in testis) (PHET) (Sunday driver 1).

RASF8_MOUSE
NC score	0.067021 (rank : 666)	θ value	θ > 10 (rank : 739)
Query Neighborhood Hits	255	Target Neighborhood Hits	391	Shared Neighborhood Hits	73
SwissProt Accessions	Q8CJ96, Q8CCW4, Q9CU91	Gene names	Rassf8
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 8 (Carcinoma-associated protein HOJ-1 homolog).

VDP_MOUSE
NC score	0.066701 (rank : 667)	θ value	θ > 10 (rank : 891)
Query Neighborhood Hits	255	Target Neighborhood Hits	469	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Z1Z0, Q3T9L9, Q3TH58, Q3U1C7, Q3UMW6, Q91WE7, Q99JZ5	Gene names	Vdp
Domain Architecture	No domain graphic available
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

TCGAP_HUMAN
NC score	0.066629 (rank : 668)	θ value	θ > 10 (rank : 849)
Query Neighborhood Hits	255	Target Neighborhood Hits	872	Shared Neighborhood Hits	49
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

LBN_HUMAN
NC score	0.066580 (rank : 669)	θ value	θ > 10 (rank : 566)
Query Neighborhood Hits	255	Target Neighborhood Hits	308	Shared Neighborhood Hits	74
SwissProt Accessions	Q86UK5, Q86YT3, Q86YT4, Q8NG49	Gene names	EVC2, LBN
Domain Architecture	No domain graphic available
Description	Limbin.

TRAK2_HUMAN
NC score	0.066517 (rank : 670)	θ value	θ > 10 (rank : 874)
Query Neighborhood Hits	255	Target Neighborhood Hits	476	Shared Neighborhood Hits	80
SwissProt Accessions	O60296, Q8WVH7, Q96NS2, Q9C0K5, Q9C0K6	Gene names	TRAK2, ALS2CR3, KIAA0549
Domain Architecture
Description	Trafficking kinesin-binding protein 2 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein).

PLCB4_HUMAN
NC score	0.065723 (rank : 671)	θ value	θ > 10 (rank : 713)
Query Neighborhood Hits	255	Target Neighborhood Hits	658	Shared Neighborhood Hits	90
SwissProt Accessions	Q15147, Q5JYS8, Q5JYT0, Q5JYT4, Q9BQW5, Q9BQW6, Q9BQW8, Q9UJQ2	Gene names	PLCB4
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-4) (PLC-beta-4).

TCRG1_MOUSE
NC score	0.065646 (rank : 672)	θ value	θ > 10 (rank : 852)
Query Neighborhood Hits	255	Target Neighborhood Hits	947	Shared Neighborhood Hits	91
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

RADI_HUMAN
NC score	0.065613 (rank : 673)	θ value	θ > 10 (rank : 734)
Query Neighborhood Hits	255	Target Neighborhood Hits	741	Shared Neighborhood Hits	99
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

AMOL1_HUMAN
NC score	0.065570 (rank : 674)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	255	Target Neighborhood Hits	435	Shared Neighborhood Hits	81
SwissProt Accessions	Q8IY63, Q63HK7, Q8NDN0, Q8WXD1, Q96CM5	Gene names	AMOTL1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

TCRG1_HUMAN
NC score	0.065515 (rank : 675)	θ value	θ > 10 (rank : 851)
Query Neighborhood Hits	255	Target Neighborhood Hits	929	Shared Neighborhood Hits	91
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

RPGR1_MOUSE
NC score	0.065395 (rank : 676)	θ value	θ > 10 (rank : 764)
Query Neighborhood Hits	255	Target Neighborhood Hits	713	Shared Neighborhood Hits	88
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

TACC3_HUMAN
NC score	0.065376 (rank : 677)	θ value	θ > 10 (rank : 844)
Query Neighborhood Hits	255	Target Neighborhood Hits	779	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

CEP35_HUMAN
NC score	0.065239 (rank : 678)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	255	Target Neighborhood Hits	811	Shared Neighborhood Hits	81
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

PKHA6_MOUSE
NC score	0.064981 (rank : 679)	θ value	θ > 10 (rank : 708)
Query Neighborhood Hits	255	Target Neighborhood Hits	591	Shared Neighborhood Hits	56
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

CIP4_HUMAN
NC score	0.064963 (rank : 680)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	255	Target Neighborhood Hits	374	Shared Neighborhood Hits	75
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

3BP5_MOUSE
NC score	0.064946 (rank : 681)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	255	Target Neighborhood Hits	346	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Z131, Q8C903, Q8VCZ0	Gene names	Sh3bp5, Sab
Domain Architecture
Description	SH3 domain-binding protein 5 (SH3 domain-binding protein that preferentially associates with BTK).

KIF3A_HUMAN
NC score	0.064904 (rank : 682)	θ value	θ > 10 (rank : 544)
Query Neighborhood Hits	255	Target Neighborhood Hits	704	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Y496, Q86XE9, Q9Y6V4	Gene names	KIF3A, KIF3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

HOME1_HUMAN
NC score	0.064868 (rank : 683)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	255	Target Neighborhood Hits	564	Shared Neighborhood Hits	88
SwissProt Accessions	Q86YM7, O96003, Q86YM5	Gene names	HOMER1, SYN47
Domain Architecture
Description	Homer protein homolog 1.

3BP5_HUMAN
NC score	0.064855 (rank : 684)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	255	Target Neighborhood Hits	375	Shared Neighborhood Hits	75
SwissProt Accessions	O60239	Gene names	SH3BP5, SAB
Domain Architecture
Description	SH3 domain-binding protein 5 (SH3 domain-binding protein that preferentially associates with BTK).

PININ_MOUSE
NC score	0.064853 (rank : 685)	θ value	θ > 10 (rank : 705)
Query Neighborhood Hits	255	Target Neighborhood Hits	777	Shared Neighborhood Hits	87
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

RADI_MOUSE
NC score	0.064668 (rank : 686)	θ value	θ > 10 (rank : 735)
Query Neighborhood Hits	255	Target Neighborhood Hits	773	Shared Neighborhood Hits	97
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

LMNB1_HUMAN
NC score	0.064586 (rank : 687)	θ value	θ > 10 (rank : 578)
Query Neighborhood Hits	255	Target Neighborhood Hits	714	Shared Neighborhood Hits	104
SwissProt Accessions	P20700, Q3SYN7, Q96EI6	Gene names	LMNB1, LMN2, LMNB
Domain Architecture
Description	Lamin-B1.

PLVAP_HUMAN
NC score	0.064295 (rank : 688)	θ value	θ > 10 (rank : 722)
Query Neighborhood Hits	255	Target Neighborhood Hits	397	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BX97, Q86VP0, Q8N8Y0, Q8ND68, Q8TER8, Q9BZD5	Gene names	PLVAP, FELS, PV1
Domain Architecture	No domain graphic available
Description	Plasmalemma vesicle-associated protein (Plasmalemma vesicle protein 1) (PV-1) (Fenestrated endothelial-linked structure protein).

KIF3A_MOUSE
NC score	0.064278 (rank : 689)	θ value	θ > 10 (rank : 545)
Query Neighborhood Hits	255	Target Neighborhood Hits	715	Shared Neighborhood Hits	104
SwissProt Accessions	P28741	Gene names	Kif3a, Kif3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

MYO5A_HUMAN
NC score	0.064260 (rank : 690)	θ value	θ > 10 (rank : 647)
Query Neighborhood Hits	255	Target Neighborhood Hits	1092	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

CCDC7_HUMAN
NC score	0.064146 (rank : 691)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	255	Target Neighborhood Hits	253	Shared Neighborhood Hits	56
SwissProt Accessions	Q96M83, Q8IVQ0, Q8NEQ0	Gene names	CCDC7
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 7.

RBBP8_HUMAN
NC score	0.064122 (rank : 692)	θ value	θ > 10 (rank : 740)
Query Neighborhood Hits	255	Target Neighborhood Hits	476	Shared Neighborhood Hits	68
SwissProt Accessions	Q99708, O75371	Gene names	RBBP8, CTIP
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 8 (RBBP-8) (CtBP-interacting protein) (CtIP) (Retinoblastoma-interacting protein and myosin-like) (RIM).

ZFY19_MOUSE
NC score	0.064014 (rank : 693)	θ value	θ > 10 (rank : 906)
Query Neighborhood Hits	255	Target Neighborhood Hits	143	Shared Neighborhood Hits	22
SwissProt Accessions	Q9DAZ9, Q8VCV7	Gene names	Zfyve19
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19.

FA50A_MOUSE
NC score	0.064002 (rank : 694)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	255	Target Neighborhood Hits	293	Shared Neighborhood Hits	63
SwissProt Accessions	Q9WV03, Q9D866	Gene names	Fam50a, D0HXS9928E, Xap5
Domain Architecture
Description	Protein FAM50A (XAP-5 protein).

LMNB1_MOUSE
NC score	0.063968 (rank : 695)	θ value	θ > 10 (rank : 579)
Query Neighborhood Hits	255	Target Neighborhood Hits	719	Shared Neighborhood Hits	101
SwissProt Accessions	P14733, Q61791	Gene names	Lmnb1
Domain Architecture
Description	Lamin-B1.

LRSM1_MOUSE
NC score	0.063899 (rank : 696)	θ value	3.0926 (rank : 198)
Query Neighborhood Hits	255	Target Neighborhood Hits	874	Shared Neighborhood Hits	83
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

DTBP1_MOUSE
NC score	0.063851 (rank : 697)	θ value	1.06291 (rank : 165)
Query Neighborhood Hits	255	Target Neighborhood Hits	209	Shared Neighborhood Hits	48
SwissProt Accessions	Q91WZ8, Q80ZN4	Gene names	Dtnbp1
Domain Architecture
Description	Dystrobrevin-binding protein 1 (Dysbindin) (Hermansky-Pudlak syndrome 7 protein homolog).

TARA_MOUSE
NC score	0.063832 (rank : 698)	θ value	θ > 10 (rank : 847)
Query Neighborhood Hits	255	Target Neighborhood Hits	1133	Shared Neighborhood Hits	102
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

CCD45_HUMAN
NC score	0.063758 (rank : 699)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	255	Target Neighborhood Hits	525	Shared Neighborhood Hits	77
SwissProt Accessions	Q96GE4, Q96M81	Gene names	CCDC45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

PKHA6_HUMAN
NC score	0.063639 (rank : 700)	θ value	θ > 10 (rank : 707)
Query Neighborhood Hits	255	Target Neighborhood Hits	556	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

INVO_MOUSE
NC score	0.063635 (rank : 701)	θ value	θ > 10 (rank : 532)
Query Neighborhood Hits	255	Target Neighborhood Hits	474	Shared Neighborhood Hits	65
SwissProt Accessions	P48997	Gene names	Ivl
Domain Architecture	No domain graphic available
Description	Involucrin.

BAIP2_HUMAN
NC score	0.063584 (rank : 702)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	255	Target Neighborhood Hits	192	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UQB8, O43858, Q53HB1, Q86WC1, Q8N5C0, Q96CR7, Q9UBR3, Q9UQ43	Gene names	BAIAP2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Protein BAP2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor substrate p53/p58) (IRSp53/58) (IRS-58) (Fas ligand-associated factor 3) (FLAF3).

LMNA_MOUSE
NC score	0.063554 (rank : 703)	θ value	θ > 10 (rank : 577)
Query Neighborhood Hits	255	Target Neighborhood Hits	661	Shared Neighborhood Hits	104
SwissProt Accessions	P48678, P11516, P97859, Q3TIH0, Q3TTS8, Q3UCA0, Q3UCJ8, Q91WF2, Q9DC21	Gene names	Lmna, Lmn1
Domain Architecture
Description	Lamin-A/C.

REN3B_HUMAN
NC score	0.063444 (rank : 704)	θ value	θ > 10 (rank : 747)
Query Neighborhood Hits	255	Target Neighborhood Hits	412	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BZI7, Q9H1J0	Gene names	UPF3B, RENT3B, UPF3X
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (hUpf3p-X).

LMNA_HUMAN
NC score	0.063425 (rank : 705)	θ value	θ > 10 (rank : 576)
Query Neighborhood Hits	255	Target Neighborhood Hits	653	Shared Neighborhood Hits	104
SwissProt Accessions	P02545, P02546, Q969I8, Q96JA2	Gene names	LMNA, LMN1
Domain Architecture
Description	Lamin-A/C (70 kDa lamin) (NY-REN-32 antigen).

BAIP2_MOUSE
NC score	0.063369 (rank : 706)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	255	Target Neighborhood Hits	185	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BKX1, Q91V97, Q923V9, Q923W0	Gene names	Baiap2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor tyrosine kinase 53 kDa substrate).

JIP4_MOUSE
NC score	0.063356 (rank : 707)	θ value	θ > 10 (rank : 534)
Query Neighborhood Hits	255	Target Neighborhood Hits	593	Shared Neighborhood Hits	77
SwissProt Accessions	Q58A65, Q3UH77, Q3UHF0, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2	Gene names	Spag9, Jip4, Jsap2, Kiaa0516, Mapk8ip4
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (JNK/SAPK-associated protein 2) (JSAP2).

FYV1_MOUSE
NC score	0.063284 (rank : 708)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	255	Target Neighborhood Hits	191	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

LMNB2_HUMAN
NC score	0.063274 (rank : 709)	θ value	θ > 10 (rank : 580)
Query Neighborhood Hits	255	Target Neighborhood Hits	723	Shared Neighborhood Hits	105
SwissProt Accessions	Q03252, O75292, Q14734, Q96DF6	Gene names	LMNB2, LMN2
Domain Architecture
Description	Lamin-B2.

ZWINT_HUMAN
NC score	0.063202 (rank : 710)	θ value	θ > 10 (rank : 914)
Query Neighborhood Hits	255	Target Neighborhood Hits	333	Shared Neighborhood Hits	61
SwissProt Accessions	O95229, Q9BWD0	Gene names	ZWINT
Domain Architecture	No domain graphic available
Description	ZW10 interactor (ZW10-interacting protein 1) (Zwint-1).

PLSI_HUMAN
NC score	0.063167 (rank : 711)	θ value	θ > 10 (rank : 717)
Query Neighborhood Hits	255	Target Neighborhood Hits	209	Shared Neighborhood Hits	34
SwissProt Accessions	Q14651	Gene names	PLS1
Domain Architecture
Description	Plastin-1 (I-plastin) (Intestine-specific plastin).

LAMA2_MOUSE
NC score	0.063149 (rank : 712)	θ value	θ > 10 (rank : 561)
Query Neighborhood Hits	255	Target Neighborhood Hits	1198	Shared Neighborhood Hits	104
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

GP73_HUMAN
NC score	0.063111 (rank : 713)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	255	Target Neighborhood Hits	309	Shared Neighborhood Hits	61
SwissProt Accessions	Q8NBJ4, Q6IAF4, Q9NRB9	Gene names	GOLPH2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

SNX18_MOUSE
NC score	0.063031 (rank : 714)	θ value	θ > 10 (rank : 805)
Query Neighborhood Hits	255	Target Neighborhood Hits	198	Shared Neighborhood Hits	31
SwissProt Accessions	Q91ZR2	Gene names	Snag1, Snx18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

TEKT1_HUMAN
NC score	0.062964 (rank : 715)	θ value	θ > 10 (rank : 853)
Query Neighborhood Hits	255	Target Neighborhood Hits	289	Shared Neighborhood Hits	68
SwissProt Accessions	Q969V4	Gene names	TEKT1
Domain Architecture
Description	Tektin-1.

KIFC3_HUMAN
NC score	0.062823 (rank : 716)	θ value	θ > 10 (rank : 553)
Query Neighborhood Hits	255	Target Neighborhood Hits	619	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BVG8, O75299, Q8IUT3, Q96HW6	Gene names	KIFC3
Domain Architecture
Description	Kinesin-like protein KIFC3.

AMOL1_MOUSE
NC score	0.062796 (rank : 717)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	255	Target Neighborhood Hits	445	Shared Neighborhood Hits	79
SwissProt Accessions	Q9D4H4, Q571F1	Gene names	Amotl1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

MYO5A_MOUSE
NC score	0.062677 (rank : 718)	θ value	θ > 10 (rank : 648)
Query Neighborhood Hits	255	Target Neighborhood Hits	1117	Shared Neighborhood Hits	105
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

DYHC_HUMAN
NC score	0.062503 (rank : 719)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	255	Target Neighborhood Hits	733	Shared Neighborhood Hits	102
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_MOUSE
NC score	0.062336 (rank : 720)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	255	Target Neighborhood Hits	729	Shared Neighborhood Hits	104
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

PLST_MOUSE
NC score	0.062277 (rank : 721)	θ value	θ > 10 (rank : 721)
Query Neighborhood Hits	255	Target Neighborhood Hits	156	Shared Neighborhood Hits	30
SwissProt Accessions	Q99K51	Gene names	Pls3
Domain Architecture	No domain graphic available
Description	Plastin-3 (T-plastin).

MAP9_MOUSE
NC score	0.062254 (rank : 722)	θ value	θ > 10 (rank : 599)
Query Neighborhood Hits	255	Target Neighborhood Hits	529	Shared Neighborhood Hits	68
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

NEB1_HUMAN
NC score	0.062206 (rank : 723)	θ value	θ > 10 (rank : 661)
Query Neighborhood Hits	255	Target Neighborhood Hits	829	Shared Neighborhood Hits	90
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

EZRI_MOUSE
NC score	0.062113 (rank : 724)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	255	Target Neighborhood Hits	693	Shared Neighborhood Hits	95
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

PLST_HUMAN
NC score	0.062016 (rank : 725)	θ value	θ > 10 (rank : 720)
Query Neighborhood Hits	255	Target Neighborhood Hits	161	Shared Neighborhood Hits	30
SwissProt Accessions	P13797, Q86YI6	Gene names	PLS3
Domain Architecture
Description	Plastin-3 (T-plastin).

ZFYV1_HUMAN
NC score	0.061990 (rank : 726)	θ value	θ > 10 (rank : 910)
Query Neighborhood Hits	255	Target Neighborhood Hits	166	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HBF4, Q8WYX7, Q96K57, Q9BXP9, Q9HCI3	Gene names	ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (Tandem FYVE fingers-1) (SR3).

ES8L3_HUMAN
NC score	0.061894 (rank : 727)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	255	Target Neighborhood Hits	206	Shared Neighborhood Hits	34
SwissProt Accessions	Q8TE67, Q5T8Q6, Q5T8Q7, Q5T8Q8, Q96E47, Q9H719	Gene names	EPS8L3, EPS8R3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

RENT2_HUMAN
NC score	0.061875 (rank : 728)	θ value	θ > 10 (rank : 748)
Query Neighborhood Hits	255	Target Neighborhood Hits	618	Shared Neighborhood Hits	75
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

LETM1_MOUSE
NC score	0.061651 (rank : 729)	θ value	θ > 10 (rank : 569)
Query Neighborhood Hits	255	Target Neighborhood Hits	240	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Z2I0, Q5PQC5, Q7TMK8, Q80ZX6, Q8CGJ3, Q8K5E5	Gene names	Letm1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

SNX18_HUMAN
NC score	0.061120 (rank : 730)	θ value	θ > 10 (rank : 804)
Query Neighborhood Hits	255	Target Neighborhood Hits	207	Shared Neighborhood Hits	31
SwissProt Accessions	Q96RF0	Gene names	SNAG1, SNX18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

DDEF2_MOUSE
NC score	0.061084 (rank : 731)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	255	Target Neighborhood Hits	625	Shared Neighborhood Hits	56
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_HUMAN
NC score	0.061083 (rank : 732)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	255	Target Neighborhood Hits	599	Shared Neighborhood Hits	58
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

SKI_MOUSE
NC score	0.061047 (rank : 733)	θ value	θ > 10 (rank : 794)
Query Neighborhood Hits	255	Target Neighborhood Hits	423	Shared Neighborhood Hits	74
SwissProt Accessions	Q60698, Q8VIL5	Gene names	Ski
Domain Architecture	No domain graphic available
Description	Ski oncogene (C-ski).

CAR14_MOUSE
NC score	0.060999 (rank : 734)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	255	Target Neighborhood Hits	526	Shared Neighborhood Hits	77
SwissProt Accessions	Q99KF0	Gene names	Card14, Bimp2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (Bcl10-interacting MAGUK protein 2) (Bimp2).

AMOT_HUMAN
NC score	0.060863 (rank : 735)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	255	Target Neighborhood Hits	712	Shared Neighborhood Hits	80
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

DZIP1_MOUSE
NC score	0.060816 (rank : 736)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	255	Target Neighborhood Hits	530	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BMD2, Q6ZQ10, Q9CRK5	Gene names	Dzip1, Kiaa0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1 homolog).

EZRI_HUMAN
NC score	0.060649 (rank : 737)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	255	Target Neighborhood Hits	663	Shared Neighborhood Hits	96
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

NDEL1_HUMAN
NC score	0.060560 (rank : 738)	θ value	θ > 10 (rank : 659)
Query Neighborhood Hits	255	Target Neighborhood Hits	415	Shared Neighborhood Hits	72
SwissProt Accessions	Q9GZM8, Q86T80, Q8TAR7, Q9UH50	Gene names	NDEL1, EOPA, MITAP1, NUDEL
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE-like 1 (Protein Nudel) (Mitosin- associated protein 1).

ES8L2_HUMAN
NC score	0.060545 (rank : 739)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	255	Target Neighborhood Hits	193	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H6S3, Q53GM8, Q8WYW7, Q96K06, Q9H6K9	Gene names	EPS8L2, EPS8R2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

PLSL_MOUSE
NC score	0.060435 (rank : 740)	θ value	θ > 10 (rank : 719)
Query Neighborhood Hits	255	Target Neighborhood Hits	170	Shared Neighborhood Hits	34
SwissProt Accessions	Q61233, Q3UE24, Q8R1X3, Q9CV77	Gene names	Lcp1, Pls2
Domain Architecture
Description	Plastin-2 (L-plastin) (Lymphocyte cytosolic protein 1) (LCP-1) (65 kDa macrophage protein) (pp65).

TARA_HUMAN
NC score	0.060296 (rank : 741)	θ value	θ > 10 (rank : 846)
Query Neighborhood Hits	255	Target Neighborhood Hits	1626	Shared Neighborhood Hits	105
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

ADIP_MOUSE
NC score	0.060204 (rank : 742)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	255	Target Neighborhood Hits	415	Shared Neighborhood Hits	68
SwissProt Accessions	Q8VC66, Q8BG59, Q8C7X0, Q8K2F7	Gene names	Ssx2ip
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein).

SKIL_HUMAN
NC score	0.060143 (rank : 743)	θ value	θ > 10 (rank : 791)
Query Neighborhood Hits	255	Target Neighborhood Hits	460	Shared Neighborhood Hits	77
SwissProt Accessions	P12757, O00464, P12756, Q07501	Gene names	SKIL, SNO
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

K0494_HUMAN
NC score	0.060069 (rank : 744)	θ value	θ > 10 (rank : 535)
Query Neighborhood Hits	255	Target Neighborhood Hits	230	Shared Neighborhood Hits	56
SwissProt Accessions	O75071	Gene names	KIAA0494
Domain Architecture	No domain graphic available
Description	Uncharacterized calcium-binding protein KIAA0494.

MYO5B_HUMAN
NC score	0.060043 (rank : 745)	θ value	θ > 10 (rank : 649)
Query Neighborhood Hits	255	Target Neighborhood Hits	911	Shared Neighborhood Hits	102
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

NDEL1_MOUSE
NC score	0.060007 (rank : 746)	θ value	θ > 10 (rank : 660)
Query Neighborhood Hits	255	Target Neighborhood Hits	420	Shared Neighborhood Hits	73
SwissProt Accessions	Q9ERR1, Q9D0Q4, Q9EPT6	Gene names	Ndel1, Nudel
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE-like 1 (Protein Nudel) (Protein mNudE-like) (mNudE-L).

KIFC3_MOUSE
NC score	0.059990 (rank : 747)	θ value	θ > 10 (rank : 554)
Query Neighborhood Hits	255	Target Neighborhood Hits	571	Shared Neighborhood Hits	90
SwissProt Accessions	O35231, Q91YQ2	Gene names	Kifc3
Domain Architecture
Description	Kinesin-like protein KIFC3.

CLC4F_MOUSE
NC score	0.059943 (rank : 748)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	255	Target Neighborhood Hits	572	Shared Neighborhood Hits	82
SwissProt Accessions	P70194, Q8BLZ8	Gene names	Clec4f, Clecsf13, Kclr
Domain Architecture
Description	C-type lectin domain family 4 member F (C-type lectin superfamily member 13) (C-type lectin 13) (Kupffer cell receptor).

ZFYV1_MOUSE
NC score	0.059882 (rank : 749)	θ value	θ > 10 (rank : 911)
Query Neighborhood Hits	255	Target Neighborhood Hits	153	Shared Neighborhood Hits	15
SwissProt Accessions	Q810J8	Gene names	Zfyve1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1.

CAR14_HUMAN
NC score	0.059844 (rank : 750)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	255	Target Neighborhood Hits	449	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BXL6, Q9BVB5	Gene names	CARD14, CARMA2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (CARD-containing MAGUK protein 2) (Carma 2).

KIF23_HUMAN
NC score	0.059689 (rank : 751)	θ value	θ > 10 (rank : 543)
Query Neighborhood Hits	255	Target Neighborhood Hits	618	Shared Neighborhood Hits	84
SwissProt Accessions	Q02241	Gene names	KIF23, KNSL5, MKLP1
Domain Architecture
Description	Kinesin-like protein KIF23 (Mitotic kinesin-like protein 1) (Kinesin- like protein 5).

STK10_MOUSE
NC score	0.059604 (rank : 752)	θ value	θ > 10 (rank : 832)
Query Neighborhood Hits	255	Target Neighborhood Hits	2132	Shared Neighborhood Hits	133
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

CCD22_MOUSE
NC score	0.059550 (rank : 753)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	255	Target Neighborhood Hits	268	Shared Neighborhood Hits	57
SwissProt Accessions	Q9JIG7, Q8BYH4	Gene names	Ccdc22, DXImx40e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 22.

BRAP_HUMAN
NC score	0.059544 (rank : 754)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	255	Target Neighborhood Hits	560	Shared Neighborhood Hits	76
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

KIFC1_HUMAN
NC score	0.059495 (rank : 755)	θ value	θ > 10 (rank : 552)
Query Neighborhood Hits	255	Target Neighborhood Hits	545	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BW19, O60887, Q14834, Q9UQP7	Gene names	KIFC1, HSET, KNSL2
Domain Architecture
Description	Kinesin-like protein KIFC1 (Kinesin-like protein 2) (Kinesin-related protein HSET).

PLSL_HUMAN
NC score	0.059404 (rank : 756)	θ value	θ > 10 (rank : 718)
Query Neighborhood Hits	255	Target Neighborhood Hits	168	Shared Neighborhood Hits	34
SwissProt Accessions	P13796	Gene names	LCP1, PLS2
Domain Architecture
Description	Plastin-2 (L-plastin) (Lymphocyte cytosolic protein 1) (LCP-1) (LC64P).

HAP1_MOUSE
NC score	0.059135 (rank : 757)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	255	Target Neighborhood Hits	388	Shared Neighborhood Hits	72
SwissProt Accessions	O35668, O35636	Gene names	Hap1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1).

ES8L2_MOUSE
NC score	0.059023 (rank : 758)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	255	Target Neighborhood Hits	169	Shared Neighborhood Hits	38
SwissProt Accessions	Q99K30, Q91VT7	Gene names	Eps8l2, Eps8r2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

CI009_MOUSE
NC score	0.059000 (rank : 759)	θ value	0.47712 (rank : 145)
Query Neighborhood Hits	255	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TPM5, Q3U293, Q9D9W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C9orf9 homolog.

CENPH_MOUSE
NC score	0.058814 (rank : 760)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	255	Target Neighborhood Hits	195	Shared Neighborhood Hits	53
SwissProt Accessions	Q9QYM8, Q8R3K9, Q9D079, Q9D0N1	Gene names	Cenph, Enp
Domain Architecture	No domain graphic available
Description	Centromere protein H (CENP-H).

ES8L3_MOUSE
NC score	0.058797 (rank : 761)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	255	Target Neighborhood Hits	168	Shared Neighborhood Hits	39
SwissProt Accessions	Q91WL0, Q3TJ14	Gene names	Eps8l3, Eps8r3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor pathway substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

KIF14_HUMAN
NC score	0.058628 (rank : 762)	θ value	θ > 10 (rank : 542)
Query Neighborhood Hits	255	Target Neighborhood Hits	732	Shared Neighborhood Hits	97
SwissProt Accessions	Q15058	Gene names	KIF14, KIAA0042
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF14.

CAR10_MOUSE
NC score	0.058560 (rank : 763)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	255	Target Neighborhood Hits	407	Shared Neighborhood Hits	83
SwissProt Accessions	P58660	Gene names	Card10, Bimp1
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (Bcl10-interacting MAGUK protein 1) (Bimp1).

NFM_MOUSE
NC score	0.058440 (rank : 764)	θ value	θ > 10 (rank : 669)
Query Neighborhood Hits	255	Target Neighborhood Hits	1159	Shared Neighborhood Hits	116
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

MAP9_HUMAN
NC score	0.058321 (rank : 765)	θ value	θ > 10 (rank : 598)
Query Neighborhood Hits	255	Target Neighborhood Hits	518	Shared Neighborhood Hits	61
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

KIF11_MOUSE
NC score	0.058249 (rank : 766)	θ value	θ > 10 (rank : 541)
Query Neighborhood Hits	255	Target Neighborhood Hits	446	Shared Neighborhood Hits	81
SwissProt Accessions	Q6P9P6, Q9Z1J0	Gene names	Kif11
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF11 (Kinesin-related motor protein Eg5).

ANR18_HUMAN
NC score	0.058201 (rank : 767)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	255	Target Neighborhood Hits	1106	Shared Neighborhood Hits	103
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

NFM_HUMAN
NC score	0.058199 (rank : 768)	θ value	θ > 10 (rank : 668)
Query Neighborhood Hits	255	Target Neighborhood Hits	1328	Shared Neighborhood Hits	118
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

MFAP1_MOUSE
NC score	0.058180 (rank : 769)	θ value	θ > 10 (rank : 604)
Query Neighborhood Hits	255	Target Neighborhood Hits	353	Shared Neighborhood Hits	58
SwissProt Accessions	Q9CQU1, Q3TU29, Q8CCL1, Q9CSJ5	Gene names	Mfap1
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 1.

PRC1_MOUSE
NC score	0.057956 (rank : 770)	θ value	θ > 10 (rank : 728)
Query Neighborhood Hits	255	Target Neighborhood Hits	382	Shared Neighborhood Hits	64
SwissProt Accessions	Q99K43, Q8CE25	Gene names	Prc1
Domain Architecture	No domain graphic available
Description	Protein regulator of cytokinesis 1.

STXB4_MOUSE
NC score	0.057909 (rank : 771)	θ value	θ > 10 (rank : 834)
Query Neighborhood Hits	255	Target Neighborhood Hits	629	Shared Neighborhood Hits	92
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

CDC37_HUMAN
NC score	0.057886 (rank : 772)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	255	Target Neighborhood Hits	506	Shared Neighborhood Hits	67
SwissProt Accessions	Q16543	Gene names	CDC37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

YO11_MOUSE
NC score	0.057678 (rank : 773)	θ value	θ > 10 (rank : 901)
Query Neighborhood Hits	255	Target Neighborhood Hits	272	Shared Neighborhood Hits	56
SwissProt Accessions	P11260	Gene names
Domain Architecture
Description	Hypothetical protein ORF-1137.

IQGA1_HUMAN
NC score	0.057527 (rank : 774)	θ value	1.38821 (rank : 177)
Query Neighborhood Hits	255	Target Neighborhood Hits	250	Shared Neighborhood Hits	53
SwissProt Accessions	P46940	Gene names	IQGAP1, KIAA0051
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1 (p195).

PHLB3_HUMAN
NC score	0.057449 (rank : 775)	θ value	θ > 10 (rank : 702)
Query Neighborhood Hits	255	Target Neighborhood Hits	304	Shared Neighborhood Hits	60
SwissProt Accessions	Q6NSJ2, Q8N7Z4	Gene names	PHLDB3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 3.

MIA_MOUSE
NC score	0.057419 (rank : 776)	θ value	θ > 10 (rank : 606)
Query Neighborhood Hits	255	Target Neighborhood Hits	17	Shared Neighborhood Hits	7
SwissProt Accessions	Q61865, O09086, P97495	Gene names	Mia, Cdrap, Mia1
Domain Architecture
Description	Melanoma-derived growth regulatory protein precursor (Melanoma inhibitory activity) (Cartilage-derived retinoic acid-sensitive protein) (CD-RAP).

IDLC_HUMAN
NC score	0.057292 (rank : 777)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	255	Target Neighborhood Hits	348	Shared Neighborhood Hits	65
SwissProt Accessions	O14645, Q5TGH0, Q7L0I5	Gene names	DNALI1
Domain Architecture	No domain graphic available
Description	Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal) (hp28).

PRC1_HUMAN
NC score	0.057205 (rank : 778)	θ value	θ > 10 (rank : 727)
Query Neighborhood Hits	255	Target Neighborhood Hits	328	Shared Neighborhood Hits	69
SwissProt Accessions	O43663, Q9BSB6	Gene names	PRC1
Domain Architecture	No domain graphic available
Description	Protein regulator of cytokinesis 1.

LAMA4_HUMAN
NC score	0.057136 (rank : 779)	θ value	θ > 10 (rank : 562)
Query Neighborhood Hits	255	Target Neighborhood Hits	708	Shared Neighborhood Hits	91
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

PPIP2_HUMAN
NC score	0.057082 (rank : 780)	θ value	θ > 10 (rank : 725)
Query Neighborhood Hits	255	Target Neighborhood Hits	254	Shared Neighborhood Hits	57
SwissProt Accessions	Q9H939	Gene names	PSTPIP2
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2.

K0494_MOUSE
NC score	0.056628 (rank : 781)	θ value	θ > 10 (rank : 536)
Query Neighborhood Hits	255	Target Neighborhood Hits	241	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BGQ6, Q3TQN6, Q8BJV7, Q8C0R1	Gene names	Kiaa0494
Domain Architecture	No domain graphic available
Description	Uncharacterized calcium-binding protein KIAA0494.

LMNB2_MOUSE
NC score	0.056487 (rank : 782)	θ value	θ > 10 (rank : 581)
Query Neighborhood Hits	255	Target Neighborhood Hits	674	Shared Neighborhood Hits	96
SwissProt Accessions	P21619, P48680, Q8CGB1	Gene names	Lmnb2
Domain Architecture
Description	Lamin-B2.

MIA_HUMAN
NC score	0.056470 (rank : 783)	θ value	θ > 10 (rank : 605)
Query Neighborhood Hits	255	Target Neighborhood Hits	19	Shared Neighborhood Hits	9
SwissProt Accessions	Q16674	Gene names	MIA
Domain Architecture
Description	Melanoma-derived growth regulatory protein precursor (Melanoma inhibitory activity).

BFSP1_HUMAN
NC score	0.056465 (rank : 784)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	255	Target Neighborhood Hits	508	Shared Neighborhood Hits	84
SwissProt Accessions	Q12934, O43595, O76034, Q9HBX4	Gene names	BFSP1
Domain Architecture
Description	Filensin (Beaded filament structural protein 1) (Lens fiber cell beaded-filament structural protein CP 115) (CP115) (Lens intermediate filament-like heavy) (LIFL-H).

BCN1_MOUSE
NC score	0.056461 (rank : 785)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	255	Target Neighborhood Hits	367	Shared Neighborhood Hits	74
SwissProt Accessions	O88597	Gene names	Becn1
Domain Architecture
Description	Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein).

SAFB2_HUMAN
NC score	0.056035 (rank : 786)	θ value	θ > 10 (rank : 773)
Query Neighborhood Hits	255	Target Neighborhood Hits	720	Shared Neighborhood Hits	82
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

LAMA3_HUMAN
NC score	0.055940 (rank : 787)	θ value	5.27518 (rank : 218)
Query Neighborhood Hits	255	Target Neighborhood Hits	760	Shared Neighborhood Hits	89
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

KIF3C_MOUSE
NC score	0.055503 (rank : 788)	θ value	1.81305 (rank : 185)
Query Neighborhood Hits	255	Target Neighborhood Hits	468	Shared Neighborhood Hits	86
SwissProt Accessions	O35066, O35229	Gene names	Kif3c
Domain Architecture
Description	Kinesin-like protein KIF3C.

BCN1_HUMAN
NC score	0.055445 (rank : 789)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	255	Target Neighborhood Hits	395	Shared Neighborhood Hits	71
SwissProt Accessions	Q14457, O75595, Q9UNA8	Gene names	BECN1, GT197
Domain Architecture
Description	Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197).

CDC37_MOUSE
NC score	0.055353 (rank : 790)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	255	Target Neighborhood Hits	359	Shared Neighborhood Hits	70
SwissProt Accessions	Q61081, Q3TGP0	Gene names	Cdc37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

BIN3_MOUSE
NC score	0.055278 (rank : 791)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	255	Target Neighborhood Hits	165	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JI08	Gene names	Bin3
Domain Architecture	No domain graphic available
Description	Bridging integrator 3.

ZC313_HUMAN
NC score	0.055269 (rank : 792)	θ value	θ > 10 (rank : 902)
Query Neighborhood Hits	255	Target Neighborhood Hits	772	Shared Neighborhood Hits	64
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

IDLC_MOUSE
NC score	0.055135 (rank : 793)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	255	Target Neighborhood Hits	321	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BVN8	Gene names	Dnali1
Domain Architecture	No domain graphic available
Description	Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal).

LAMB1_HUMAN
NC score	0.055074 (rank : 794)	θ value	0.279714 (rank : 138)
Query Neighborhood Hits	255	Target Neighborhood Hits	1018	Shared Neighborhood Hits	97
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

KIF3C_HUMAN
NC score	0.055016 (rank : 795)	θ value	0.62314 (rank : 156)
Query Neighborhood Hits	255	Target Neighborhood Hits	478	Shared Neighborhood Hits	85
SwissProt Accessions	O14782, O43544	Gene names	KIF3C
Domain Architecture
Description	Kinesin-like protein KIF3C.

CCD22_HUMAN
NC score	0.055000 (rank : 796)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	255	Target Neighborhood Hits	242	Shared Neighborhood Hits	58
SwissProt Accessions	O60826	Gene names	CCDC22, CXorf37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 22.

PPIP2_MOUSE
NC score	0.054922 (rank : 797)	θ value	θ > 10 (rank : 726)
Query Neighborhood Hits	255	Target Neighborhood Hits	308	Shared Neighborhood Hits	58
SwissProt Accessions	Q99M15, Q9Z189	Gene names	Pstpip2, Mayp
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2 (Macrophage actin-associated tyrosine-phosphorylated protein) (pp37).

PKHA5_HUMAN
NC score	0.054901 (rank : 798)	θ value	θ > 10 (rank : 706)
Query Neighborhood Hits	255	Target Neighborhood Hits	455	Shared Neighborhood Hits	68
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

RHG26_HUMAN
NC score	0.054804 (rank : 799)	θ value	θ > 10 (rank : 754)
Query Neighborhood Hits	255	Target Neighborhood Hits	281	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

EPS8_MOUSE
NC score	0.054705 (rank : 800)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	255	Target Neighborhood Hits	157	Shared Neighborhood Hits	36
SwissProt Accessions	Q08509	Gene names	Eps8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

STK10_HUMAN
NC score	0.054673 (rank : 801)	θ value	θ > 10 (rank : 831)
Query Neighborhood Hits	255	Target Neighborhood Hits	1921	Shared Neighborhood Hits	131
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

U2AFM_HUMAN
NC score	0.054562 (rank : 802)	θ value	θ > 10 (rank : 885)
Query Neighborhood Hits	255	Target Neighborhood Hits	577	Shared Neighborhood Hits	76
SwissProt Accessions	Q15696	Gene names	ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (NY-REN-20 antigen).

CEP72_MOUSE
NC score	0.054541 (rank : 803)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	255	Target Neighborhood Hits	381	Shared Neighborhood Hits	59
SwissProt Accessions	Q9D3R3, Q8BM53, Q9D0B7	Gene names	Cep72
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 72 kDa (Cep72 protein).

SHLB2_MOUSE
NC score	0.054369 (rank : 804)	θ value	θ > 10 (rank : 790)
Query Neighborhood Hits	255	Target Neighborhood Hits	88	Shared Neighborhood Hits	22
SwissProt Accessions	Q8R3V5, Q8K140, Q91ZI7	Gene names	Sh3glb2, Kiaa1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

GLE1_MOUSE
NC score	0.054140 (rank : 805)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	255	Target Neighborhood Hits	504	Shared Neighborhood Hits	71
SwissProt Accessions	Q8R322, Q3TT10, Q3TU23, Q3UD65, Q8BT16, Q9D4A6	Gene names	Gle1l
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein).

SKI_HUMAN
NC score	0.054107 (rank : 806)	θ value	θ > 10 (rank : 793)
Query Neighborhood Hits	255	Target Neighborhood Hits	423	Shared Neighborhood Hits	73
SwissProt Accessions	P12755, Q5SYT7	Gene names	SKI
Domain Architecture
Description	Ski oncogene (C-ski).

TNNT3_HUMAN
NC score	0.053959 (rank : 807)	θ value	θ > 10 (rank : 860)
Query Neighborhood Hits	255	Target Neighborhood Hits	327	Shared Neighborhood Hits	63
SwissProt Accessions	P45378, Q12975, Q12976, Q12977, Q12978, Q86TH6	Gene names	TNNT3
Domain Architecture	No domain graphic available
Description	Troponin T, fast skeletal muscle (TnTf) (Fast skeletal muscle troponin T) (fTnT) (Beta TnTF).

TNNT3_MOUSE
NC score	0.053944 (rank : 808)	θ value	θ > 10 (rank : 861)
Query Neighborhood Hits	255	Target Neighborhood Hits	317	Shared Neighborhood Hits	64
SwissProt Accessions	Q9QZ47, O35575, O35576, O35577, O35578, O35579, O35580, O35581, O35582, O35583, O35584, O35585, P97456, Q99L89, Q9QZ46	Gene names	Tnnt3
Domain Architecture	No domain graphic available
Description	Troponin T, fast skeletal muscle (TnTf) (Fast skeletal muscle troponin T) (fTnT).

KIF3B_HUMAN
NC score	0.053929 (rank : 809)	θ value	θ > 10 (rank : 546)
Query Neighborhood Hits	255	Target Neighborhood Hits	540	Shared Neighborhood Hits	90
SwissProt Accessions	O15066	Gene names	KIF3B, KIAA0359
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B) (HH0048).

ASPM_MOUSE
NC score	0.053885 (rank : 810)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	255	Target Neighborhood Hits	150	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CJ27, O88482, Q8BJI8, Q8BKT4	Gene names	Aspm, Calmbp1, Sha1
Domain Architecture
Description	Abnormal spindle-like microcephaly-associated protein homolog (Calmodulin-binding protein 1) (Spindle and hydroxyurea checkpoint abnormal protein) (Calmodulin-binding protein Sha1).

CNN1_HUMAN
NC score	0.053782 (rank : 811)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	255	Target Neighborhood Hits	38	Shared Neighborhood Hits	11
SwissProt Accessions	P51911, O00638, Q15416, Q8IY93, Q99438	Gene names	CNN1
Domain Architecture
Description	Calponin-1 (Calponin H1, smooth muscle) (Basic calponin).

CNN1_MOUSE
NC score	0.053626 (rank : 812)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	255	Target Neighborhood Hits	37	Shared Neighborhood Hits	10
SwissProt Accessions	Q08091	Gene names	Cnn1
Domain Architecture
Description	Calponin-1 (Calponin H1, smooth muscle) (Basic calponin).

KIF3B_MOUSE
NC score	0.053473 (rank : 813)	θ value	θ > 10 (rank : 547)
Query Neighborhood Hits	255	Target Neighborhood Hits	533	Shared Neighborhood Hits	88
SwissProt Accessions	Q61771	Gene names	Kif3b
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B).

DDEF1_MOUSE
NC score	0.053398 (rank : 814)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	255	Target Neighborhood Hits	592	Shared Neighborhood Hits	45
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

M3K9_HUMAN
NC score	0.053384 (rank : 815)	θ value	0.813845 (rank : 160)
Query Neighborhood Hits	255	Target Neighborhood Hits	1123	Shared Neighborhood Hits	71
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

M3KL4_HUMAN
NC score	0.053328 (rank : 816)	θ value	θ > 10 (rank : 594)
Query Neighborhood Hits	255	Target Neighborhood Hits	1087	Shared Neighborhood Hits	80
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

SHLB2_HUMAN
NC score	0.052984 (rank : 817)	θ value	θ > 10 (rank : 789)
Query Neighborhood Hits	255	Target Neighborhood Hits	86	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NR46, Q8WY61, Q96JH9	Gene names	SH3GLB2, KIAA1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

U2AFM_MOUSE
NC score	0.052939 (rank : 818)	θ value	θ > 10 (rank : 886)
Query Neighborhood Hits	255	Target Neighborhood Hits	543	Shared Neighborhood Hits	74
SwissProt Accessions	Q62377	Gene names	Zrsr2, U2af1-rs2, U2af1l2, U2af1rs2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2).

CNN2_MOUSE
NC score	0.052925 (rank : 819)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	255	Target Neighborhood Hits	39	Shared Neighborhood Hits	10
SwissProt Accessions	Q08093	Gene names	Cnn2
Domain Architecture
Description	Calponin-2 (Calponin H2, smooth muscle) (Neutral calponin).

CLUA1_MOUSE
NC score	0.052906 (rank : 820)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	255	Target Neighborhood Hits	261	Shared Neighborhood Hits	60
SwissProt Accessions	Q8R3P7, Q6P3Y8	Gene names	Cluap1
Domain Architecture	No domain graphic available
Description	Clusterin-associated protein 1.

WDFY3_HUMAN
NC score	0.052827 (rank : 821)	θ value	θ > 10 (rank : 895)
Query Neighborhood Hits	255	Target Neighborhood Hits	348	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IZQ1, Q4W5K5, Q6P0Q5, Q8N1T2, Q96BS7, Q96N85, Q9Y2J7	Gene names	WDFY3, KIAA0993
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy).

EPS8_HUMAN
NC score	0.052816 (rank : 822)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	255	Target Neighborhood Hits	151	Shared Neighborhood Hits	35
SwissProt Accessions	Q12929, Q8N6J0	Gene names	EPS8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

CJ068_HUMAN
NC score	0.052812 (rank : 823)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	255	Target Neighborhood Hits	316	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H943, Q8N7T7	Gene names	C10orf68
Domain Architecture	No domain graphic available
Description	Protein C10orf68.

FYN_MOUSE
NC score	0.052667 (rank : 824)	θ value	3.0926 (rank : 197)
Query Neighborhood Hits	255	Target Neighborhood Hits	1073	Shared Neighborhood Hits	55
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

TRDN_HUMAN
NC score	0.052660 (rank : 825)	θ value	θ > 10 (rank : 875)
Query Neighborhood Hits	255	Target Neighborhood Hits	542	Shared Neighborhood Hits	61
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

LAMC1_HUMAN
NC score	0.052630 (rank : 826)	θ value	θ > 10 (rank : 563)
Query Neighborhood Hits	255	Target Neighborhood Hits	922	Shared Neighborhood Hits	103
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

WDFY3_MOUSE
NC score	0.052625 (rank : 827)	θ value	θ > 10 (rank : 896)
Query Neighborhood Hits	255	Target Neighborhood Hits	332	Shared Neighborhood Hits	22
SwissProt Accessions	Q6VNB8, Q8C8H7	Gene names	Wdfy3
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Beach domain, WD repeat and FYVE domain-containing protein 1) (BWF1).

LRRF1_HUMAN
NC score	0.052607 (rank : 828)	θ value	θ > 10 (rank : 585)
Query Neighborhood Hits	255	Target Neighborhood Hits	625	Shared Neighborhood Hits	71
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

IMMT_MOUSE
NC score	0.052486 (rank : 829)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	255	Target Neighborhood Hits	326	Shared Neighborhood Hits	72
SwissProt Accessions	Q8CAQ8, Q66JS4, Q7TNE2, Q8C7V1, Q8CCI0, Q8CDA8, Q9D9F6	Gene names	Immt
Domain Architecture	No domain graphic available
Description	Mitochondrial inner membrane protein (Mitofilin).

SPC24_HUMAN
NC score	0.052466 (rank : 830)	θ value	θ > 10 (rank : 812)
Query Neighborhood Hits	255	Target Neighborhood Hits	324	Shared Neighborhood Hits	61
SwissProt Accessions	Q8NBT2	Gene names	SPBC24
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc24 (hSpc24).

RNF8_MOUSE
NC score	0.052332 (rank : 831)	θ value	θ > 10 (rank : 759)
Query Neighborhood Hits	255	Target Neighborhood Hits	618	Shared Neighborhood Hits	76
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

NUP88_HUMAN
NC score	0.052320 (rank : 832)	θ value	θ > 10 (rank : 677)
Query Neighborhood Hits	255	Target Neighborhood Hits	354	Shared Neighborhood Hits	65
SwissProt Accessions	Q99567, Q9BWE5	Gene names	NUP88
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup88 (Nucleoporin Nup88) (88 kDa nuclear pore complex protein).

MERL_MOUSE
NC score	0.052118 (rank : 833)	θ value	θ > 10 (rank : 603)
Query Neighborhood Hits	255	Target Neighborhood Hits	524	Shared Neighborhood Hits	87
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

M3K11_HUMAN
NC score	0.052017 (rank : 834)	θ value	1.06291 (rank : 169)
Query Neighborhood Hits	255	Target Neighborhood Hits	1136	Shared Neighborhood Hits	67
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

FA50A_HUMAN
NC score	0.051818 (rank : 835)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	255	Target Neighborhood Hits	264	Shared Neighborhood Hits	60
SwissProt Accessions	Q14320, Q5HY37	Gene names	FAM50A, DXS9928E, HXC26, XAP5
Domain Architecture
Description	Protein FAM50A (Protein XAP-5) (Protein HXC-26).

ZRF1_MOUSE
NC score	0.051744 (rank : 836)	θ value	θ > 10 (rank : 913)
Query Neighborhood Hits	255	Target Neighborhood Hits	414	Shared Neighborhood Hits	63
SwissProt Accessions	P54103	Gene names	Zrf1, Dnajc2
Domain Architecture
Description	Zuotin-related factor 1.

CN045_HUMAN
NC score	0.051663 (rank : 837)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	255	Target Neighborhood Hits	227	Shared Neighborhood Hits	50
SwissProt Accessions	Q8ND07, Q9H5P8	Gene names	C14orf45
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf45.

RBP1_HUMAN
NC score	0.051529 (rank : 838)	θ value	θ > 10 (rank : 746)
Query Neighborhood Hits	255	Target Neighborhood Hits	521	Shared Neighborhood Hits	81
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

KI20A_HUMAN
NC score	0.051499 (rank : 839)	θ value	θ > 10 (rank : 539)
Query Neighborhood Hits	255	Target Neighborhood Hits	321	Shared Neighborhood Hits	64
SwissProt Accessions	O95235	Gene names	KIF20A, RAB6KIFL
Domain Architecture
Description	Kinesin family member 20A (Rabkinesin-6) (Rab6-interacting kinesin- like protein) (GG10_2).

YES_MOUSE
NC score	0.051491 (rank : 840)	θ value	θ > 10 (rank : 900)
Query Neighborhood Hits	255	Target Neighborhood Hits	1052	Shared Neighborhood Hits	56
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

SPC25_HUMAN
NC score	0.051429 (rank : 841)	θ value	θ > 10 (rank : 813)
Query Neighborhood Hits	255	Target Neighborhood Hits	273	Shared Neighborhood Hits	62
SwissProt Accessions	Q9HBM1	Gene names	SPBC25, SPC25
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc25 (hSpc25).

MERL_HUMAN
NC score	0.051419 (rank : 842)	θ value	θ > 10 (rank : 602)
Query Neighborhood Hits	255	Target Neighborhood Hits	532	Shared Neighborhood Hits	87
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

APOA1_MOUSE
NC score	0.051374 (rank : 843)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	255	Target Neighborhood Hits	210	Shared Neighborhood Hits	52
SwissProt Accessions	Q00623	Gene names	Apoa1
Domain Architecture
Description	Apolipoprotein A-I precursor (Apo-AI) (ApoA-I).

YES_HUMAN
NC score	0.051225 (rank : 844)	θ value	θ > 10 (rank : 899)
Query Neighborhood Hits	255	Target Neighborhood Hits	1059	Shared Neighborhood Hits	56
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

WDFY1_HUMAN
NC score	0.051215 (rank : 845)	θ value	θ > 10 (rank : 894)
Query Neighborhood Hits	255	Target Neighborhood Hits	305	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IWB7, Q9H9D5, Q9P2B3	Gene names	WDFY1, KIAA1435, WDF1, ZFYVE17
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 1 (WD40- and FYVE domain- containing protein 1) (Phosphoinositide-binding protein 1) (FENS-1) (Zinc finger FYVE domain-containing protein 17).

NTBP1_MOUSE
NC score	0.051112 (rank : 846)	θ value	θ > 10 (rank : 674)
Query Neighborhood Hits	255	Target Neighborhood Hits	528	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BRM2, Q8CAA8	Gene names	Scyl1bp1, Ntklbp1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like-binding protein 1 (NTKL-binding protein 1) (NTKL-BP1) (mNTKL-BP1) (SCY1-like 1-binding protein 1) (SCYL1-binding protein 1) (SCYL1-BP1).

MRCKG_MOUSE
NC score	0.051073 (rank : 847)	θ value	θ > 10 (rank : 624)
Query Neighborhood Hits	255	Target Neighborhood Hits	1466	Shared Neighborhood Hits	122
SwissProt Accessions	Q80UW5	Gene names	Cdc42bpg
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

GLE1_HUMAN
NC score	0.051006 (rank : 848)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	255	Target Neighborhood Hits	445	Shared Neighborhood Hits	64
SwissProt Accessions	Q53GS7, O75458, Q53GT9, Q5VVU1, Q8NCP6, Q9UFL6	Gene names	GLE1L, GLE1
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein) (hGLE1).

FYN_HUMAN
NC score	0.050901 (rank : 849)	θ value	3.0926 (rank : 196)
Query Neighborhood Hits	255	Target Neighborhood Hits	1078	Shared Neighborhood Hits	55
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

DRP2_HUMAN
NC score	0.050841 (rank : 850)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	255	Target Neighborhood Hits	186	Shared Neighborhood Hits	45
SwissProt Accessions	Q13474	Gene names	DRP2
Domain Architecture
Description	Dystrophin-related protein 2.

CNN3_HUMAN
NC score	0.050737 (rank : 851)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	255	Target Neighborhood Hits	43	Shared Neighborhood Hits	11
SwissProt Accessions	Q15417	Gene names	CNN3
Domain Architecture
Description	Calponin-3 (Calponin, acidic isoform).

CNN3_MOUSE
NC score	0.050687 (rank : 852)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	255	Target Neighborhood Hits	45	Shared Neighborhood Hits	11
SwissProt Accessions	Q9DAW9, Q3TW23	Gene names	Cnn3
Domain Architecture	No domain graphic available
Description	Calponin-3 (Calponin, acidic isoform).

GFAP_HUMAN
NC score	0.050633 (rank : 853)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	255	Target Neighborhood Hits	723	Shared Neighborhood Hits	108
SwissProt Accessions	P14136, Q53H98, Q5D055, Q6ZQS3, Q7Z5J6, Q7Z5J7, Q96KS4, Q96P18, Q9UFD0	Gene names	GFAP
Domain Architecture
Description	Glial fibrillary acidic protein, astrocyte (GFAP).

CENPU_HUMAN
NC score	0.050503 (rank : 854)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	255	Target Neighborhood Hits	289	Shared Neighborhood Hits	61
SwissProt Accessions	Q71F23, Q32Q71, Q9H5G1	Gene names	MLF1IP, CENPU, ICEN24, KLIP1
Domain Architecture	No domain graphic available
Description	Centromere protein U (CENP-U) (CENP-U(50)) (CENP-50) (Interphase centromere complex protein 24) (MLF1-interacting protein) (KSHV latent nuclear antigen-interacting protein 1).

MRCKG_HUMAN
NC score	0.050363 (rank : 855)	θ value	θ > 10 (rank : 623)
Query Neighborhood Hits	255	Target Neighborhood Hits	1519	Shared Neighborhood Hits	119
SwissProt Accessions	Q6DT37, O00565	Gene names	CDC42BPG
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

PCQAP_HUMAN
NC score	0.050363 (rank : 856)	θ value	θ > 10 (rank : 696)
Query Neighborhood Hits	255	Target Neighborhood Hits	549	Shared Neighborhood Hits	55
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

TNNT2_HUMAN
NC score	0.050235 (rank : 857)	θ value	θ > 10 (rank : 859)
Query Neighborhood Hits	255	Target Neighborhood Hits	433	Shared Neighborhood Hits	68
SwissProt Accessions	P45379, O60214, Q99596, Q99597, Q9UM96	Gene names	TNNT2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

SEC20_HUMAN
NC score	0.050018 (rank : 858)	θ value	θ > 10 (rank : 777)
Query Neighborhood Hits	255	Target Neighborhood Hits	200	Shared Neighborhood Hits	52
SwissProt Accessions	Q12981, O75622, O75623, O75624, Q6K044, Q96FG4	Gene names	BNIP1, NIP1, SEC20L, TRG8
Domain Architecture
Description	Vesicle transport protein SEC20 (BCL2/adenovirus E1B 19 kDa protein- interacting protein 1) (Transformation-related gene 8 protein) (TRG- 8).

SYCP3_HUMAN
NC score	0.046760 (rank : 859)	θ value	3.0926 (rank : 203)
Query Neighborhood Hits	255	Target Neighborhood Hits	276	Shared Neighborhood Hits	45
SwissProt Accessions	Q8IZU3	Gene names	SYCP3, SCP3
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 3 (SCP-3).

CD72_MOUSE
NC score	0.045750 (rank : 860)	θ value	6.88961 (rank : 228)
Query Neighborhood Hits	255	Target Neighborhood Hits	262	Shared Neighborhood Hits	53
SwissProt Accessions	P21855, Q64225	Gene names	Cd72, Ly-32, Lyb-2
Domain Architecture
Description	B-cell differentiation antigen CD72 (Lyb-2) (Antigen Ly-32).

PRP31_HUMAN
NC score	0.045463 (rank : 861)	θ value	0.21417 (rank : 133)
Query Neighborhood Hits	255	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WWY3, Q8N7F9, Q9H271, Q9Y439	Gene names	PRPF31, PRP31
Domain Architecture	No domain graphic available
Description	U4/U6 small nuclear ribonucleoprotein Prp31 (Pre-mRNA-processing factor 31) (U4/U6 snRNP 61 kDa protein) (hPrp31) (Protein 61K) (Serologically defined breast cancer antigen NY-BR-99).

HCK_HUMAN
NC score	0.044958 (rank : 862)	θ value	1.38821 (rank : 176)
Query Neighborhood Hits	255	Target Neighborhood Hits	1035	Shared Neighborhood Hits	54
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

HCK_MOUSE
NC score	0.044798 (rank : 863)	θ value	1.06291 (rank : 166)
Query Neighborhood Hits	255	Target Neighborhood Hits	1029	Shared Neighborhood Hits	56
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

FRK_HUMAN
NC score	0.044199 (rank : 864)	θ value	2.36792 (rank : 189)
Query Neighborhood Hits	255	Target Neighborhood Hits	1058	Shared Neighborhood Hits	58
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

LYN_HUMAN
NC score	0.043988 (rank : 865)	θ value	0.0563607 (rank : 107)
Query Neighborhood Hits	255	Target Neighborhood Hits	1022	Shared Neighborhood Hits	52
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

BLK_HUMAN
NC score	0.043529 (rank : 866)	θ value	3.0926 (rank : 194)
Query Neighborhood Hits	255	Target Neighborhood Hits	994	Shared Neighborhood Hits	51
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

IQGA3_HUMAN
NC score	0.043461 (rank : 867)	θ value	0.47712 (rank : 149)
Query Neighborhood Hits	255	Target Neighborhood Hits	125	Shared Neighborhood Hits	26
SwissProt Accessions	Q86VI3	Gene names	IQGAP3
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP3.

LYN_MOUSE
NC score	0.042767 (rank : 868)	θ value	0.125558 (rank : 120)
Query Neighborhood Hits	255	Target Neighborhood Hits	1023	Shared Neighborhood Hits	49
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

PRP31_MOUSE
NC score	0.042593 (rank : 869)	θ value	0.47712 (rank : 152)
Query Neighborhood Hits	255	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CCF0, Q6P7X2, Q8BQ91, Q8C8U4, Q8C8V5, Q8CCG6, Q8CF52, Q8VBW3	Gene names	Prpf31, Prp31
Domain Architecture	No domain graphic available
Description	U4/U6 small nuclear ribonucleoprotein Prp31 (Pre-mRNA-processing factor 31) (U4/U6 snRNP 61 kDa protein) (Protein 61K).

HDAC9_MOUSE
NC score	0.038336 (rank : 870)	θ value	8.99809 (rank : 244)
Query Neighborhood Hits	255	Target Neighborhood Hits	186	Shared Neighborhood Hits	43
SwissProt Accessions	Q99N13, Q9EPT2	Gene names	Hdac9, Hdac7b, Hdrp, Mitr
Domain Architecture	No domain graphic available
Description	Histone deacetylase 9 (HD9) (HD7B) (Histone deacetylase-related protein) (MEF2-interacting transcription repressor MITR).

PTN23_HUMAN
NC score	0.037848 (rank : 871)	θ value	0.0330416 (rank : 94)
Query Neighborhood Hits	255	Target Neighborhood Hits	646	Shared Neighborhood Hits	63
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTN23_MOUSE
NC score	0.033918 (rank : 872)	θ value	3.0926 (rank : 202)
Query Neighborhood Hits	255	Target Neighborhood Hits	726	Shared Neighborhood Hits	67
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

MATK_MOUSE
NC score	0.032596 (rank : 873)	θ value	0.62314 (rank : 157)
Query Neighborhood Hits	255	Target Neighborhood Hits	952	Shared Neighborhood Hits	37
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

C8AP2_HUMAN
NC score	0.032223 (rank : 874)	θ value	4.03905 (rank : 205)
Query Neighborhood Hits	255	Target Neighborhood Hits	548	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

K1C18_HUMAN
NC score	0.031370 (rank : 875)	θ value	8.99809 (rank : 245)
Query Neighborhood Hits	255	Target Neighborhood Hits	441	Shared Neighborhood Hits	78
SwissProt Accessions	P05783, Q9BW26	Gene names	KRT18, CYK18
Domain Architecture
Description	Keratin, type I cytoskeletal 18 (Cytokeratin-18) (CK-18) (Keratin-18) (K18).

MATK_HUMAN
NC score	0.030765 (rank : 876)	θ value	8.99809 (rank : 250)
Query Neighborhood Hits	255	Target Neighborhood Hits	954	Shared Neighborhood Hits	41
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

DCTN2_HUMAN
NC score	0.029960 (rank : 877)	θ value	6.88961 (rank : 231)
Query Neighborhood Hits	255	Target Neighborhood Hits	72	Shared Neighborhood Hits	23
SwissProt Accessions	Q13561, Q86YN2, Q9BW17	Gene names	DCTN2, DCTN50
Domain Architecture
Description	Dynactin subunit 2 (Dynactin complex 50 kDa subunit) (50 kDa dynein- associated polypeptide) (p50 dynamitin) (DCTN-50).

SIL1_MOUSE
NC score	0.029061 (rank : 878)	θ value	2.36792 (rank : 192)
Query Neighborhood Hits	255	Target Neighborhood Hits	68	Shared Neighborhood Hits	16
SwissProt Accessions	Q9EPK6, Q91V34	Gene names	Sil1
Domain Architecture	No domain graphic available
Description	Nucleotide exchange factor SIL1 precursor.

CF146_MOUSE
NC score	0.028200 (rank : 879)	θ value	1.81305 (rank : 179)
Query Neighborhood Hits	255	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D9W6	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf146 homolog.

DNMT1_HUMAN
NC score	0.027793 (rank : 880)	θ value	0.47712 (rank : 146)
Query Neighborhood Hits	255	Target Neighborhood Hits	401	Shared Neighborhood Hits	27
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

SFPQ_MOUSE
NC score	0.027790 (rank : 881)	θ value	8.99809 (rank : 254)
Query Neighborhood Hits	255	Target Neighborhood Hits	958	Shared Neighborhood Hits	60
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

AHTF1_HUMAN
NC score	0.027425 (rank : 882)	θ value	3.0926 (rank : 193)
Query Neighborhood Hits	255	Target Neighborhood Hits	286	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WYP5, Q7Z4E3, Q8IZA4, Q96EH9, Q9Y4Q6	Gene names	AHCTF1, ELYS, TMBS62
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

S3TC1_HUMAN
NC score	0.026133 (rank : 883)	θ value	6.88961 (rank : 237)
Query Neighborhood Hits	255	Target Neighborhood Hits	78	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TE82	Gene names	SH3TC1
Domain Architecture	No domain graphic available
Description	SH3 domain and tetratricopeptide repeats-containing protein 1.

K0999_MOUSE
NC score	0.023304 (rank : 884)	θ value	4.03905 (rank : 210)
Query Neighborhood Hits	255	Target Neighborhood Hits	931	Shared Neighborhood Hits	28
SwissProt Accessions	Q6P4S6, Q641L5, Q66JZ5, Q6ZQ09, Q8K075, Q9CYD5	Gene names	Kiaa0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).

HDAC9_HUMAN
NC score	0.023189 (rank : 885)	θ value	4.03905 (rank : 209)
Query Neighborhood Hits	255	Target Neighborhood Hits	201	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UKV0, O94845, O95028	Gene names	HDAC9, HDAC7, HDAC7B, KIAA0744
Domain Architecture
Description	Histone deacetylase 9 (HD9) (HD7B) (HD7).

NOL8_MOUSE
NC score	0.022601 (rank : 886)	θ value	5.27518 (rank : 223)
Query Neighborhood Hits	255	Target Neighborhood Hits	210	Shared Neighborhood Hits	17
SwissProt Accessions	Q3UHX0, Q504M4, Q8CDJ7, Q9CUR0	Gene names	Nol8
Domain Architecture	No domain graphic available
Description	Nucleolar protein 8.

CALB1_HUMAN
NC score	0.020786 (rank : 887)	θ value	5.27518 (rank : 213)
Query Neighborhood Hits	255	Target Neighborhood Hits	130	Shared Neighborhood Hits	12
SwissProt Accessions	P05937	Gene names	CALB1, CAB27
Domain Architecture
Description	Calbindin (Vitamin D-dependent calcium-binding protein, avian-type) (Calbindin D28) (D-28K).

KS6B1_HUMAN
NC score	0.020573 (rank : 888)	θ value	1.81305 (rank : 186)
Query Neighborhood Hits	255	Target Neighborhood Hits	850	Shared Neighborhood Hits	23
SwissProt Accessions	P23443	Gene names	RPS6KB1
Domain Architecture
Description	Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1) (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) (p70-S6K) (P70S6K) (p70-alpha).

KGP1B_MOUSE
NC score	0.020507 (rank : 889)	θ value	8.99809 (rank : 247)
Query Neighborhood Hits	255	Target Neighborhood Hits	922	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Z0Z0	Gene names	Prkg1, Prkg1b, Prkgr1b
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP1B_HUMAN
NC score	0.020506 (rank : 890)	θ value	8.99809 (rank : 246)
Query Neighborhood Hits	255	Target Neighborhood Hits	921	Shared Neighborhood Hits	34
SwissProt Accessions	P14619	Gene names	PRKG1, PRKG1B, PRKGR1B
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

SETX_HUMAN
NC score	0.020007 (rank : 891)	θ value	6.88961 (rank : 238)
Query Neighborhood Hits	255	Target Neighborhood Hits	368	Shared Neighborhood Hits	30
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

CALB1_MOUSE
NC score	0.018250 (rank : 892)	θ value	5.27518 (rank : 214)
Query Neighborhood Hits	255	Target Neighborhood Hits	129	Shared Neighborhood Hits	9
SwissProt Accessions	P12658, Q545N6	Gene names	Calb1
Domain Architecture
Description	Calbindin (Vitamin D-dependent calcium-binding protein, avian-type) (Calbindin D28) (D-28K) (Spot 35 protein) (PCD-29).

NOL8_HUMAN
NC score	0.017891 (rank : 893)	θ value	5.27518 (rank : 222)
Query Neighborhood Hits	255	Target Neighborhood Hits	297	Shared Neighborhood Hits	15
SwissProt Accessions	Q76FK4, Q5TCC7, Q5TCC8, Q5TCD3, Q5TCD5, Q5TCD6, Q5TCD7, Q76D35, Q7L3E2, Q9H586, Q9H795, Q9H7W7, Q9H9J6, Q9NWA4, Q9NWM4	Gene names	NOL8, NOP132
Domain Architecture	No domain graphic available
Description	Nucleolar protein 8 (Nucleolar protein Nop132).

SDCG1_MOUSE
NC score	0.017656 (rank : 894)	θ value	8.99809 (rank : 253)
Query Neighborhood Hits	255	Target Neighborhood Hits	168	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CCP0, Q66JX6, Q8C9R6, Q8CA65, Q8JZT9, Q8R072, Q9CW30, Q9CYB8, Q9D4A9	Gene names	Sdccag1
Domain Architecture
Description	Serologically defined colon cancer antigen 1.

CCG3_MOUSE
NC score	0.016912 (rank : 895)	θ value	1.38821 (rank : 172)
Query Neighborhood Hits	255	Target Neighborhood Hits	38	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JJV5	Gene names	Cacng3
Domain Architecture
Description	Voltage-dependent calcium channel gamma-3 subunit (Neuronal voltage- gated calcium channel gamma-3 subunit).

MPP2_MOUSE
NC score	0.016828 (rank : 896)	θ value	5.27518 (rank : 220)
Query Neighborhood Hits	255	Target Neighborhood Hits	189	Shared Neighborhood Hits	21
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

ADDB_MOUSE
NC score	0.016705 (rank : 897)	θ value	0.47712 (rank : 143)
Query Neighborhood Hits	255	Target Neighborhood Hits	574	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

LAMC3_MOUSE
NC score	0.015752 (rank : 898)	θ value	8.99809 (rank : 249)
Query Neighborhood Hits	255	Target Neighborhood Hits	624	Shared Neighborhood Hits	54
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

PROM1_MOUSE
NC score	0.015518 (rank : 899)	θ value	8.99809 (rank : 251)
Query Neighborhood Hits	255	Target Neighborhood Hits	77	Shared Neighborhood Hits	13
SwissProt Accessions	O54990, O35408	Gene names	Prom1, Prom, Proml1
Domain Architecture
Description	Prominin-1 precursor (Prominin-like protein 1) (Antigen AC133 homolog).

CCG3_HUMAN
NC score	0.015440 (rank : 900)	θ value	2.36792 (rank : 187)
Query Neighborhood Hits	255	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	O60359	Gene names	CACNG3
Domain Architecture
Description	Voltage-dependent calcium channel gamma-3 subunit (Neuronal voltage- gated calcium channel gamma-3 subunit).

DPOD3_MOUSE
NC score	0.013977 (rank : 901)	θ value	5.27518 (rank : 215)
Query Neighborhood Hits	255	Target Neighborhood Hits	118	Shared Neighborhood Hits	6
SwissProt Accessions	Q9EQ28	Gene names	Pold3
Domain Architecture	No domain graphic available
Description	DNA polymerase subunit delta 3 (DNA polymerase subunit delta p66).

ATF6B_MOUSE
NC score	0.010458 (rank : 902)	θ value	8.99809 (rank : 240)
Query Neighborhood Hits	255	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	O35451	Gene names	Crebl1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp).

MAGI1_MOUSE
NC score	0.009010 (rank : 903)	θ value	5.27518 (rank : 219)
Query Neighborhood Hits	255	Target Neighborhood Hits	403	Shared Neighborhood Hits	10
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

TOM70_HUMAN
NC score	0.008583 (rank : 904)	θ value	3.0926 (rank : 204)
Query Neighborhood Hits	255	Target Neighborhood Hits	127	Shared Neighborhood Hits	3
SwissProt Accessions	O94826	Gene names	TOMM70A, KIAA0719
Domain Architecture
Description	Mitochondrial precursor proteins import receptor (Translocase of outer membrane TOM70).

CENG2_HUMAN
NC score	0.008050 (rank : 905)	θ value	1.38821 (rank : 173)
Query Neighborhood Hits	255	Target Neighborhood Hits	471	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

CENG2_MOUSE
NC score	0.005891 (rank : 906)	θ value	6.88961 (rank : 229)
Query Neighborhood Hits	255	Target Neighborhood Hits	463	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

GBX1_HUMAN
NC score	0.003843 (rank : 907)	θ value	1.38821 (rank : 175)
Query Neighborhood Hits	255	Target Neighborhood Hits	334	Shared Neighborhood Hits	6
SwissProt Accessions	Q14549	Gene names	GBX1
Domain Architecture	No domain graphic available
Description	Homeobox protein GBX-1 (Gastrulation and brain-specific homeobox protein 1).

GP151_MOUSE
NC score	0.003305 (rank : 908)	θ value	5.27518 (rank : 217)
Query Neighborhood Hits	255	Target Neighborhood Hits	248	Shared Neighborhood Hits	2
SwissProt Accessions	Q7TSN6, Q80UD8, Q8BX88	Gene names	Gpr151, Pgr7
Domain Architecture
Description	Probable G-protein coupled receptor 151 protein (G-protein coupled receptor PGR7) (GPCR-2037).

DDX24_HUMAN
NC score	0.002918 (rank : 909)	θ value	4.03905 (rank : 208)
Query Neighborhood Hits	255	Target Neighborhood Hits	190	Shared Neighborhood Hits	3
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

GBX1_MOUSE
NC score	0.002023 (rank : 910)	θ value	5.27518 (rank : 216)
Query Neighborhood Hits	255	Target Neighborhood Hits	350	Shared Neighborhood Hits	6
SwissProt Accessions	P82976, Q8CGW5	Gene names	Gbx1
Domain Architecture	No domain graphic available
Description	Homeobox protein GBX-1 (Gastrulation and brain-specific homeobox protein 1).

DLX3_MOUSE
NC score	0.001121 (rank : 911)	θ value	6.88961 (rank : 233)
Query Neighborhood Hits	255	Target Neighborhood Hits	367	Shared Neighborhood Hits	8
SwissProt Accessions	Q64205	Gene names	Dlx3
Domain Architecture
Description	Homeobox protein DLX-3.

DLX3_HUMAN
NC score	0.000761 (rank : 912)	θ value	6.88961 (rank : 232)
Query Neighborhood Hits	255	Target Neighborhood Hits	369	Shared Neighborhood Hits	7
SwissProt Accessions	O60479	Gene names	DLX3
Domain Architecture
Description	Homeobox protein DLX-3.

RBM19_MOUSE
NC score	0.000586 (rank : 913)	θ value	8.99809 (rank : 252)
Query Neighborhood Hits	255	Target Neighborhood Hits	296	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R3C6, Q8BHR0, Q9CW63	Gene names	Rbm19
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 19 (RNA-binding motif protein 19).

PRRX2_HUMAN
NC score	-0.000305 (rank : 914)	θ value	6.88961 (rank : 236)
Query Neighborhood Hits	255	Target Neighborhood Hits	348	Shared Neighborhood Hits	6
SwissProt Accessions	Q99811, Q9UIB3	Gene names	PRRX2, PMX2, PRX2
Domain Architecture
Description	Paired mesoderm homeobox protein 2 (PRX-2) (Paired-related homeobox protein 2).

ZN445_MOUSE
NC score	-0.008034 (rank : 915)	θ value	6.88961 (rank : 239)
Query Neighborhood Hits	255	Target Neighborhood Hits	760	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R2V3, Q8K216	Gene names	Znf445, Zfp445
Domain Architecture
Description	Zinc finger protein 445.