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Network neighborhood for query Sequence : CNN1_MOUSE

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CNN1_MOUSE
SwissProt Accessions	Q08091	Gene names	Cnn1
Domain Architecture
Description	Calponin-1 (Calponin H1, smooth muscle) (Basic calponin).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CNN1_MOUSE
θ value	1.46527e-159 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	37	Target Neighborhood Hits	37	Shared Neighborhood Hits	37
SwissProt Accessions	Q08091	Gene names	Cnn1
Domain Architecture
Description	Calponin-1 (Calponin H1, smooth muscle) (Basic calponin).

CNN1_HUMAN
θ value	1.51632e-156 (rank : 2)	NC score	0.999896 (rank : 2)
Query Neighborhood Hits	37	Target Neighborhood Hits	38	Shared Neighborhood Hits	37
SwissProt Accessions	P51911, O00638, Q15416, Q8IY93, Q99438	Gene names	CNN1
Domain Architecture
Description	Calponin-1 (Calponin H1, smooth muscle) (Basic calponin).

CNN3_HUMAN
θ value	8.41738e-115 (rank : 3)	NC score	0.991756 (rank : 4)
Query Neighborhood Hits	37	Target Neighborhood Hits	43	Shared Neighborhood Hits	33
SwissProt Accessions	Q15417	Gene names	CNN3
Domain Architecture
Description	Calponin-3 (Calponin, acidic isoform).

CNN3_MOUSE
θ value	7.12574e-114 (rank : 4)	NC score	0.992243 (rank : 3)
Query Neighborhood Hits	37	Target Neighborhood Hits	45	Shared Neighborhood Hits	34
SwissProt Accessions	Q9DAW9, Q3TW23	Gene names	Cnn3
Domain Architecture	No domain graphic available
Description	Calponin-3 (Calponin, acidic isoform).

CNN2_MOUSE
θ value	1.18001e-100 (rank : 5)	NC score	0.990759 (rank : 6)
Query Neighborhood Hits	37	Target Neighborhood Hits	39	Shared Neighborhood Hits	33
SwissProt Accessions	Q08093	Gene names	Cnn2
Domain Architecture
Description	Calponin-2 (Calponin H2, smooth muscle) (Neutral calponin).

CNN2_HUMAN
θ value	1.30465e-99 (rank : 6)	NC score	0.990932 (rank : 5)
Query Neighborhood Hits	37	Target Neighborhood Hits	37	Shared Neighborhood Hits	33
SwissProt Accessions	Q99439, Q92578	Gene names	CNN2
Domain Architecture
Description	Calponin-2 (Calponin H2, smooth muscle) (Neutral calponin).

TAGL2_HUMAN
θ value	1.73584e-35 (rank : 7)	NC score	0.893164 (rank : 9)
Query Neighborhood Hits	37	Target Neighborhood Hits	35	Shared Neighborhood Hits	28
SwissProt Accessions	P37802, Q5JRQ6, Q5JRQ7, Q9BUH5, Q9H4P0	Gene names	TAGLN2, KIAA0120
Domain Architecture
Description	Transgelin-2 (SM22-alpha homolog).

TAGL3_HUMAN
θ value	1.46948e-34 (rank : 8)	NC score	0.893407 (rank : 8)
Query Neighborhood Hits	37	Target Neighborhood Hits	33	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UI15, Q96A74	Gene names	TAGLN3, NP25
Domain Architecture
Description	Transgelin-3 (Neuronal protein NP25) (Neuronal protein 22) (NP22).

TAGL3_MOUSE
θ value	1.9192e-34 (rank : 9)	NC score	0.892197 (rank : 10)
Query Neighborhood Hits	37	Target Neighborhood Hits	33	Shared Neighborhood Hits	27
SwissProt Accessions	Q9R1Q8	Gene names	Tagln3, Np25
Domain Architecture
Description	Transgelin-3 (Neuronal protein NP25).

TAGL_HUMAN
θ value	8.06329e-33 (rank : 10)	NC score	0.893605 (rank : 7)
Query Neighborhood Hits	37	Target Neighborhood Hits	32	Shared Neighborhood Hits	29
SwissProt Accessions	Q01995, O15542	Gene names	TAGLN, SM22, WS3-10
Domain Architecture
Description	Transgelin (Smooth muscle protein 22-alpha) (SM22-alpha) (WS3-10) (22 kDa actin-binding protein).

TAGL2_MOUSE
θ value	1.79631e-32 (rank : 11)	NC score	0.889103 (rank : 12)
Query Neighborhood Hits	37	Target Neighborhood Hits	42	Shared Neighborhood Hits	30
SwissProt Accessions	Q9WVA4	Gene names	Tagln2
Domain Architecture
Description	Transgelin-2.

TAGL_MOUSE
θ value	3.06405e-32 (rank : 12)	NC score	0.892091 (rank : 11)
Query Neighborhood Hits	37	Target Neighborhood Hits	33	Shared Neighborhood Hits	29
SwissProt Accessions	P37804, Q545W0	Gene names	Tagln, Sm22, Sm22a
Domain Architecture
Description	Transgelin (Smooth muscle protein 22-alpha) (SM22-alpha) (Actin- associated protein p27).

LMO7_HUMAN
θ value	2.36244e-08 (rank : 13)	NC score	0.421276 (rank : 13)
Query Neighborhood Hits	37	Target Neighborhood Hits	507	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

ARHG6_HUMAN
θ value	4.45536e-07 (rank : 14)	NC score	0.243209 (rank : 15)
Query Neighborhood Hits	37	Target Neighborhood Hits	376	Shared Neighborhood Hits	30
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

ARHG6_MOUSE
θ value	5.81887e-07 (rank : 15)	NC score	0.256366 (rank : 14)
Query Neighborhood Hits	37	Target Neighborhood Hits	394	Shared Neighborhood Hits	30
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

VAV2_MOUSE
θ value	1.09739e-05 (rank : 16)	NC score	0.226728 (rank : 19)
Query Neighborhood Hits	37	Target Neighborhood Hits	456	Shared Neighborhood Hits	30
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

VAV2_HUMAN
θ value	1.43324e-05 (rank : 17)	NC score	0.227058 (rank : 18)
Query Neighborhood Hits	37	Target Neighborhood Hits	453	Shared Neighborhood Hits	30
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

VAV3_MOUSE
θ value	0.000121331 (rank : 18)	NC score	0.237040 (rank : 16)
Query Neighborhood Hits	37	Target Neighborhood Hits	404	Shared Neighborhood Hits	30
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

VAV_HUMAN
θ value	0.000121331 (rank : 19)	NC score	0.223157 (rank : 21)
Query Neighborhood Hits	37	Target Neighborhood Hits	452	Shared Neighborhood Hits	30
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

VAV_MOUSE
θ value	0.000121331 (rank : 20)	NC score	0.229342 (rank : 17)
Query Neighborhood Hits	37	Target Neighborhood Hits	430	Shared Neighborhood Hits	30
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

LRCH4_HUMAN
θ value	0.000461057 (rank : 21)	NC score	0.176623 (rank : 29)
Query Neighborhood Hits	37	Target Neighborhood Hits	305	Shared Neighborhood Hits	28
SwissProt Accessions	O75427, Q8WV85, Q96ID0	Gene names	LRCH4, LRN, LRRN4
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 4 (Leucine-rich neuronal protein).

VAV3_HUMAN
θ value	0.000602161 (rank : 22)	NC score	0.223279 (rank : 20)
Query Neighborhood Hits	37	Target Neighborhood Hits	398	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

LRCH1_HUMAN
θ value	0.000786445 (rank : 23)	NC score	0.219235 (rank : 22)
Query Neighborhood Hits	37	Target Neighborhood Hits	266	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y2L9, Q7Z5F6, Q7Z5F7	Gene names	LRCH1, CHDC1, KIAA1016
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1) (Neuronal protein 81) (NP81).

LRCH1_MOUSE
θ value	0.00102713 (rank : 24)	NC score	0.218653 (rank : 23)
Query Neighborhood Hits	37	Target Neighborhood Hits	264	Shared Neighborhood Hits	34
SwissProt Accessions	P62046	Gene names	Lrch1, Chdc1, Kiaa1016
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1).

LRCH2_HUMAN
θ value	0.00175202 (rank : 25)	NC score	0.196008 (rank : 25)
Query Neighborhood Hits	37	Target Neighborhood Hits	315	Shared Neighborhood Hits	29
SwissProt Accessions	Q5VUJ6, Q9HA88, Q9P233	Gene names	LRCH2, KIAA1495
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 2.

LRCH4_MOUSE
θ value	0.00298849 (rank : 26)	NC score	0.182492 (rank : 28)
Query Neighborhood Hits	37	Target Neighborhood Hits	302	Shared Neighborhood Hits	30
SwissProt Accessions	Q921G6	Gene names	Lrch4
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 4.

LRCH2_MOUSE
θ value	0.00390308 (rank : 27)	NC score	0.192980 (rank : 26)
Query Neighborhood Hits	37	Target Neighborhood Hits	287	Shared Neighborhood Hits	29
SwissProt Accessions	Q3UMG5, Q7TNP9, Q80TC9	Gene names	Lrch2, Kiaa1495
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 2.

LRCH3_HUMAN
θ value	0.00390308 (rank : 28)	NC score	0.201520 (rank : 24)
Query Neighborhood Hits	37	Target Neighborhood Hits	270	Shared Neighborhood Hits	32
SwissProt Accessions	Q96II8, Q96FP9, Q9NT52	Gene names	LRCH3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 3 precursor.

ARHG7_HUMAN
θ value	0.00509761 (rank : 29)	NC score	0.162174 (rank : 30)
Query Neighborhood Hits	37	Target Neighborhood Hits	347	Shared Neighborhood Hits	22
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

GA2L2_MOUSE
θ value	0.0252991 (rank : 30)	NC score	0.104988 (rank : 33)
Query Neighborhood Hits	37	Target Neighborhood Hits	395	Shared Neighborhood Hits	12
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

LRCH3_MOUSE
θ value	0.0330416 (rank : 31)	NC score	0.190592 (rank : 27)
Query Neighborhood Hits	37	Target Neighborhood Hits	257	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BVU0, Q3U222, Q3UZ74	Gene names	Lrch3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 3 precursor.

GA2L2_HUMAN
θ value	0.0431538 (rank : 32)	NC score	0.115328 (rank : 32)
Query Neighborhood Hits	37	Target Neighborhood Hits	175	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NHY3, Q8NHY4	Gene names	GAS2L2, GAR17
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2) (GAS2-related protein on chromosome 17) (GAR17 protein).

GA2L3_HUMAN
θ value	0.21417 (rank : 33)	NC score	0.116546 (rank : 31)
Query Neighborhood Hits	37	Target Neighborhood Hits	189	Shared Neighborhood Hits	16
SwissProt Accessions	Q86XJ1	Gene names	GAS2L3
Domain Architecture	No domain graphic available
Description	GAS2-like protein 3 (Growth arrest-specific 2-like 3).

GAS2_HUMAN
θ value	1.06291 (rank : 34)	NC score	0.083855 (rank : 34)
Query Neighborhood Hits	37	Target Neighborhood Hits	22	Shared Neighborhood Hits	14
SwissProt Accessions	O43903, Q6ICV8	Gene names	GAS2
Domain Architecture
Description	Growth-arrest-specific protein 2 (GAS-2).

SPTN4_HUMAN
θ value	3.0926 (rank : 35)	NC score	0.005499 (rank : 47)
Query Neighborhood Hits	37	Target Neighborhood Hits	570	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H254, Q9H1K7, Q9H1K8, Q9H1K9, Q9H3G8, Q9HCD0	Gene names	SPTBN4, KIAA1642, SPTBN3
Domain Architecture
Description	Spectrin beta chain, brain 3 (Spectrin, non-erythroid beta chain 3) (Beta-IV spectrin).

GAS2_MOUSE
θ value	6.88961 (rank : 36)	NC score	0.070452 (rank : 37)
Query Neighborhood Hits	37	Target Neighborhood Hits	22	Shared Neighborhood Hits	14
SwissProt Accessions	P11862	Gene names	Gas2, Gas-2
Domain Architecture
Description	Growth-arrest-specific protein 2 (GAS-2).

UBR1_HUMAN
θ value	8.99809 (rank : 37)	NC score	0.013216 (rank : 46)
Query Neighborhood Hits	37	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IWV7, O60708, O75492, Q68DN9, Q8IWY6, Q96JY4	Gene names	UBR1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-1 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-1) (Ubiquitin-protein ligase E3- alpha-I).

ARHG4_HUMAN
θ value	θ > 10 (rank : 38)	NC score	0.061246 (rank : 39)
Query Neighborhood Hits	37	Target Neighborhood Hits	242	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG4_MOUSE
θ value	θ > 10 (rank : 39)	NC score	0.064533 (rank : 38)
Query Neighborhood Hits	37	Target Neighborhood Hits	185	Shared Neighborhood Hits	9
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG7_MOUSE
θ value	θ > 10 (rank : 40)	NC score	0.079740 (rank : 35)
Query Neighborhood Hits	37	Target Neighborhood Hits	396	Shared Neighborhood Hits	9
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

ARHG9_HUMAN
θ value	θ > 10 (rank : 41)	NC score	0.059622 (rank : 42)
Query Neighborhood Hits	37	Target Neighborhood Hits	235	Shared Neighborhood Hits	9
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

ARHG9_MOUSE
θ value	θ > 10 (rank : 42)	NC score	0.059638 (rank : 41)
Query Neighborhood Hits	37	Target Neighborhood Hits	234	Shared Neighborhood Hits	9
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

MCF2L_MOUSE
θ value	θ > 10 (rank : 43)	NC score	0.053626 (rank : 45)
Query Neighborhood Hits	37	Target Neighborhood Hits	255	Shared Neighborhood Hits	10
SwissProt Accessions	Q64096	Gene names	Mcf2l, Dbs
Domain Architecture
Description	Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2- transforming sequence-like protein).

PKHG1_HUMAN
θ value	θ > 10 (rank : 44)	NC score	0.073031 (rank : 36)
Query Neighborhood Hits	37	Target Neighborhood Hits	174	Shared Neighborhood Hits	9
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

PREX1_HUMAN
θ value	θ > 10 (rank : 45)	NC score	0.060734 (rank : 40)
Query Neighborhood Hits	37	Target Neighborhood Hits	177	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

TIAM1_HUMAN
θ value	θ > 10 (rank : 46)	NC score	0.055003 (rank : 44)
Query Neighborhood Hits	37	Target Neighborhood Hits	225	Shared Neighborhood Hits	9
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TIAM1_MOUSE
θ value	θ > 10 (rank : 47)	NC score	0.055679 (rank : 43)
Query Neighborhood Hits	37	Target Neighborhood Hits	205	Shared Neighborhood Hits	9
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

Hits sorted by NC score

CNN1_MOUSE
NC score	0.999962 (rank : 1)	θ value	1.46527e-159 (rank : 1)
Query Neighborhood Hits	37	Target Neighborhood Hits	37	Shared Neighborhood Hits	37
SwissProt Accessions	Q08091	Gene names	Cnn1
Domain Architecture
Description	Calponin-1 (Calponin H1, smooth muscle) (Basic calponin).

CNN1_HUMAN
NC score	0.999896 (rank : 2)	θ value	1.51632e-156 (rank : 2)
Query Neighborhood Hits	37	Target Neighborhood Hits	38	Shared Neighborhood Hits	37
SwissProt Accessions	P51911, O00638, Q15416, Q8IY93, Q99438	Gene names	CNN1
Domain Architecture
Description	Calponin-1 (Calponin H1, smooth muscle) (Basic calponin).

CNN3_MOUSE
NC score	0.992243 (rank : 3)	θ value	7.12574e-114 (rank : 4)
Query Neighborhood Hits	37	Target Neighborhood Hits	45	Shared Neighborhood Hits	34
SwissProt Accessions	Q9DAW9, Q3TW23	Gene names	Cnn3
Domain Architecture	No domain graphic available
Description	Calponin-3 (Calponin, acidic isoform).

CNN3_HUMAN
NC score	0.991756 (rank : 4)	θ value	8.41738e-115 (rank : 3)
Query Neighborhood Hits	37	Target Neighborhood Hits	43	Shared Neighborhood Hits	33
SwissProt Accessions	Q15417	Gene names	CNN3
Domain Architecture
Description	Calponin-3 (Calponin, acidic isoform).

CNN2_HUMAN
NC score	0.990932 (rank : 5)	θ value	1.30465e-99 (rank : 6)
Query Neighborhood Hits	37	Target Neighborhood Hits	37	Shared Neighborhood Hits	33
SwissProt Accessions	Q99439, Q92578	Gene names	CNN2
Domain Architecture
Description	Calponin-2 (Calponin H2, smooth muscle) (Neutral calponin).

CNN2_MOUSE
NC score	0.990759 (rank : 6)	θ value	1.18001e-100 (rank : 5)
Query Neighborhood Hits	37	Target Neighborhood Hits	39	Shared Neighborhood Hits	33
SwissProt Accessions	Q08093	Gene names	Cnn2
Domain Architecture
Description	Calponin-2 (Calponin H2, smooth muscle) (Neutral calponin).

TAGL_HUMAN
NC score	0.893605 (rank : 7)	θ value	8.06329e-33 (rank : 10)
Query Neighborhood Hits	37	Target Neighborhood Hits	32	Shared Neighborhood Hits	29
SwissProt Accessions	Q01995, O15542	Gene names	TAGLN, SM22, WS3-10
Domain Architecture
Description	Transgelin (Smooth muscle protein 22-alpha) (SM22-alpha) (WS3-10) (22 kDa actin-binding protein).

TAGL3_HUMAN
NC score	0.893407 (rank : 8)	θ value	1.46948e-34 (rank : 8)
Query Neighborhood Hits	37	Target Neighborhood Hits	33	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UI15, Q96A74	Gene names	TAGLN3, NP25
Domain Architecture
Description	Transgelin-3 (Neuronal protein NP25) (Neuronal protein 22) (NP22).

TAGL2_HUMAN
NC score	0.893164 (rank : 9)	θ value	1.73584e-35 (rank : 7)
Query Neighborhood Hits	37	Target Neighborhood Hits	35	Shared Neighborhood Hits	28
SwissProt Accessions	P37802, Q5JRQ6, Q5JRQ7, Q9BUH5, Q9H4P0	Gene names	TAGLN2, KIAA0120
Domain Architecture
Description	Transgelin-2 (SM22-alpha homolog).

TAGL3_MOUSE
NC score	0.892197 (rank : 10)	θ value	1.9192e-34 (rank : 9)
Query Neighborhood Hits	37	Target Neighborhood Hits	33	Shared Neighborhood Hits	27
SwissProt Accessions	Q9R1Q8	Gene names	Tagln3, Np25
Domain Architecture
Description	Transgelin-3 (Neuronal protein NP25).

TAGL_MOUSE
NC score	0.892091 (rank : 11)	θ value	3.06405e-32 (rank : 12)
Query Neighborhood Hits	37	Target Neighborhood Hits	33	Shared Neighborhood Hits	29
SwissProt Accessions	P37804, Q545W0	Gene names	Tagln, Sm22, Sm22a
Domain Architecture
Description	Transgelin (Smooth muscle protein 22-alpha) (SM22-alpha) (Actin- associated protein p27).

TAGL2_MOUSE
NC score	0.889103 (rank : 12)	θ value	1.79631e-32 (rank : 11)
Query Neighborhood Hits	37	Target Neighborhood Hits	42	Shared Neighborhood Hits	30
SwissProt Accessions	Q9WVA4	Gene names	Tagln2
Domain Architecture
Description	Transgelin-2.

LMO7_HUMAN
NC score	0.421276 (rank : 13)	θ value	2.36244e-08 (rank : 13)
Query Neighborhood Hits	37	Target Neighborhood Hits	507	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

ARHG6_MOUSE
NC score	0.256366 (rank : 14)	θ value	5.81887e-07 (rank : 15)
Query Neighborhood Hits	37	Target Neighborhood Hits	394	Shared Neighborhood Hits	30
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

ARHG6_HUMAN
NC score	0.243209 (rank : 15)	θ value	4.45536e-07 (rank : 14)
Query Neighborhood Hits	37	Target Neighborhood Hits	376	Shared Neighborhood Hits	30
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

VAV3_MOUSE
NC score	0.237040 (rank : 16)	θ value	0.000121331 (rank : 18)
Query Neighborhood Hits	37	Target Neighborhood Hits	404	Shared Neighborhood Hits	30
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

VAV_MOUSE
NC score	0.229342 (rank : 17)	θ value	0.000121331 (rank : 20)
Query Neighborhood Hits	37	Target Neighborhood Hits	430	Shared Neighborhood Hits	30
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

VAV2_HUMAN
NC score	0.227058 (rank : 18)	θ value	1.43324e-05 (rank : 17)
Query Neighborhood Hits	37	Target Neighborhood Hits	453	Shared Neighborhood Hits	30
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

VAV2_MOUSE
NC score	0.226728 (rank : 19)	θ value	1.09739e-05 (rank : 16)
Query Neighborhood Hits	37	Target Neighborhood Hits	456	Shared Neighborhood Hits	30
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

VAV3_HUMAN
NC score	0.223279 (rank : 20)	θ value	0.000602161 (rank : 22)
Query Neighborhood Hits	37	Target Neighborhood Hits	398	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

VAV_HUMAN
NC score	0.223157 (rank : 21)	θ value	0.000121331 (rank : 19)
Query Neighborhood Hits	37	Target Neighborhood Hits	452	Shared Neighborhood Hits	30
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

LRCH1_HUMAN
NC score	0.219235 (rank : 22)	θ value	0.000786445 (rank : 23)
Query Neighborhood Hits	37	Target Neighborhood Hits	266	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y2L9, Q7Z5F6, Q7Z5F7	Gene names	LRCH1, CHDC1, KIAA1016
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1) (Neuronal protein 81) (NP81).

LRCH1_MOUSE
NC score	0.218653 (rank : 23)	θ value	0.00102713 (rank : 24)
Query Neighborhood Hits	37	Target Neighborhood Hits	264	Shared Neighborhood Hits	34
SwissProt Accessions	P62046	Gene names	Lrch1, Chdc1, Kiaa1016
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1).

LRCH3_HUMAN
NC score	0.201520 (rank : 24)	θ value	0.00390308 (rank : 28)
Query Neighborhood Hits	37	Target Neighborhood Hits	270	Shared Neighborhood Hits	32
SwissProt Accessions	Q96II8, Q96FP9, Q9NT52	Gene names	LRCH3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 3 precursor.

LRCH2_HUMAN
NC score	0.196008 (rank : 25)	θ value	0.00175202 (rank : 25)
Query Neighborhood Hits	37	Target Neighborhood Hits	315	Shared Neighborhood Hits	29
SwissProt Accessions	Q5VUJ6, Q9HA88, Q9P233	Gene names	LRCH2, KIAA1495
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 2.

LRCH2_MOUSE
NC score	0.192980 (rank : 26)	θ value	0.00390308 (rank : 27)
Query Neighborhood Hits	37	Target Neighborhood Hits	287	Shared Neighborhood Hits	29
SwissProt Accessions	Q3UMG5, Q7TNP9, Q80TC9	Gene names	Lrch2, Kiaa1495
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 2.

LRCH3_MOUSE
NC score	0.190592 (rank : 27)	θ value	0.0330416 (rank : 31)
Query Neighborhood Hits	37	Target Neighborhood Hits	257	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BVU0, Q3U222, Q3UZ74	Gene names	Lrch3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 3 precursor.

LRCH4_MOUSE
NC score	0.182492 (rank : 28)	θ value	0.00298849 (rank : 26)
Query Neighborhood Hits	37	Target Neighborhood Hits	302	Shared Neighborhood Hits	30
SwissProt Accessions	Q921G6	Gene names	Lrch4
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 4.

LRCH4_HUMAN
NC score	0.176623 (rank : 29)	θ value	0.000461057 (rank : 21)
Query Neighborhood Hits	37	Target Neighborhood Hits	305	Shared Neighborhood Hits	28
SwissProt Accessions	O75427, Q8WV85, Q96ID0	Gene names	LRCH4, LRN, LRRN4
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 4 (Leucine-rich neuronal protein).

ARHG7_HUMAN
NC score	0.162174 (rank : 30)	θ value	0.00509761 (rank : 29)
Query Neighborhood Hits	37	Target Neighborhood Hits	347	Shared Neighborhood Hits	22
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

GA2L3_HUMAN
NC score	0.116546 (rank : 31)	θ value	0.21417 (rank : 33)
Query Neighborhood Hits	37	Target Neighborhood Hits	189	Shared Neighborhood Hits	16
SwissProt Accessions	Q86XJ1	Gene names	GAS2L3
Domain Architecture	No domain graphic available
Description	GAS2-like protein 3 (Growth arrest-specific 2-like 3).

GA2L2_HUMAN
NC score	0.115328 (rank : 32)	θ value	0.0431538 (rank : 32)
Query Neighborhood Hits	37	Target Neighborhood Hits	175	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NHY3, Q8NHY4	Gene names	GAS2L2, GAR17
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2) (GAS2-related protein on chromosome 17) (GAR17 protein).

GA2L2_MOUSE
NC score	0.104988 (rank : 33)	θ value	0.0252991 (rank : 30)
Query Neighborhood Hits	37	Target Neighborhood Hits	395	Shared Neighborhood Hits	12
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

GAS2_HUMAN
NC score	0.083855 (rank : 34)	θ value	1.06291 (rank : 34)
Query Neighborhood Hits	37	Target Neighborhood Hits	22	Shared Neighborhood Hits	14
SwissProt Accessions	O43903, Q6ICV8	Gene names	GAS2
Domain Architecture
Description	Growth-arrest-specific protein 2 (GAS-2).

ARHG7_MOUSE
NC score	0.079740 (rank : 35)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	37	Target Neighborhood Hits	396	Shared Neighborhood Hits	9
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

PKHG1_HUMAN
NC score	0.073031 (rank : 36)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	37	Target Neighborhood Hits	174	Shared Neighborhood Hits	9
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

GAS2_MOUSE
NC score	0.070452 (rank : 37)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	37	Target Neighborhood Hits	22	Shared Neighborhood Hits	14
SwissProt Accessions	P11862	Gene names	Gas2, Gas-2
Domain Architecture
Description	Growth-arrest-specific protein 2 (GAS-2).

ARHG4_MOUSE
NC score	0.064533 (rank : 38)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	37	Target Neighborhood Hits	185	Shared Neighborhood Hits	9
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG4_HUMAN
NC score	0.061246 (rank : 39)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	37	Target Neighborhood Hits	242	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

PREX1_HUMAN
NC score	0.060734 (rank : 40)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	37	Target Neighborhood Hits	177	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

ARHG9_MOUSE
NC score	0.059638 (rank : 41)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	37	Target Neighborhood Hits	234	Shared Neighborhood Hits	9
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

ARHG9_HUMAN
NC score	0.059622 (rank : 42)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	37	Target Neighborhood Hits	235	Shared Neighborhood Hits	9
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

TIAM1_MOUSE
NC score	0.055679 (rank : 43)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	37	Target Neighborhood Hits	205	Shared Neighborhood Hits	9
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TIAM1_HUMAN
NC score	0.055003 (rank : 44)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	37	Target Neighborhood Hits	225	Shared Neighborhood Hits	9
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

MCF2L_MOUSE
NC score	0.053626 (rank : 45)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	37	Target Neighborhood Hits	255	Shared Neighborhood Hits	10
SwissProt Accessions	Q64096	Gene names	Mcf2l, Dbs
Domain Architecture
Description	Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2- transforming sequence-like protein).

UBR1_HUMAN
NC score	0.013216 (rank : 46)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	37	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IWV7, O60708, O75492, Q68DN9, Q8IWY6, Q96JY4	Gene names	UBR1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-1 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-1) (Ubiquitin-protein ligase E3- alpha-I).

SPTN4_HUMAN
NC score	0.005499 (rank : 47)	θ value	3.0926 (rank : 35)
Query Neighborhood Hits	37	Target Neighborhood Hits	570	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H254, Q9H1K7, Q9H1K8, Q9H1K9, Q9H3G8, Q9HCD0	Gene names	SPTBN4, KIAA1642, SPTBN3
Domain Architecture
Description	Spectrin beta chain, brain 3 (Spectrin, non-erythroid beta chain 3) (Beta-IV spectrin).