Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : ZFY27_MOUSE

For an explanation of this page, click here

ZFY27_MOUSE
SwissProt Accessions	Q3TXX3, Q8CFP8	Gene names	Zfyve27
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 27.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ZFY27_HUMAN
θ value	0 (rank : 1)	NC score	0.994712 (rank : 2)
Query Neighborhood Hits	53	Target Neighborhood Hits	64	Shared Neighborhood Hits	48
SwissProt Accessions	Q5T4F4, Q5T4F1, Q5T4F2, Q5T4F3, Q8N1K0, Q8N6D6, Q8NCA0, Q8NDE4, Q96M08	Gene names	ZFYVE27
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 27.

ZFY27_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	53	Target Neighborhood Hits	53	Shared Neighborhood Hits	53
SwissProt Accessions	Q3TXX3, Q8CFP8	Gene names	Zfyve27
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 27.

ZFY19_HUMAN
θ value	2.21117e-06 (rank : 3)	NC score	0.449883 (rank : 7)
Query Neighborhood Hits	53	Target Neighborhood Hits	206	Shared Neighborhood Hits	41
SwissProt Accessions	Q96K21, Q86WC2, Q8WU96	Gene names	ZFYVE19, MPFYVE
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19 (MLL partner containing FYVE domain).

MTMR3_HUMAN
θ value	2.88788e-06 (rank : 4)	NC score	0.285604 (rank : 17)
Query Neighborhood Hits	53	Target Neighborhood Hits	163	Shared Neighborhood Hits	45
SwissProt Accessions	Q13615, Q9NYN5, Q9NYN6, Q9UDX6, Q9UEG3	Gene names	MTMR3, KIAA0371, ZFYVE10
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Zinc finger FYVE domain-containing protein 10).

ZFY19_MOUSE
θ value	6.43352e-06 (rank : 5)	NC score	0.456033 (rank : 6)
Query Neighborhood Hits	53	Target Neighborhood Hits	143	Shared Neighborhood Hits	42
SwissProt Accessions	Q9DAZ9, Q8VCV7	Gene names	Zfyve19
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19.

ZFY28_HUMAN
θ value	6.43352e-06 (rank : 6)	NC score	0.471241 (rank : 5)
Query Neighborhood Hits	53	Target Neighborhood Hits	152	Shared Neighborhood Hits	44
SwissProt Accessions	Q9HCC9	Gene names	ZFYVE28, KIAA1643
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 28.

ZFY21_HUMAN
θ value	1.87187e-05 (rank : 7)	NC score	0.485593 (rank : 3)
Query Neighborhood Hits	53	Target Neighborhood Hits	72	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BQ24, Q86T05, Q96LT1	Gene names	ZFYVE21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

ZFY21_MOUSE
θ value	3.19293e-05 (rank : 8)	NC score	0.484103 (rank : 4)
Query Neighborhood Hits	53	Target Neighborhood Hits	72	Shared Neighborhood Hits	44
SwissProt Accessions	Q8VCM3, Q9D1E2	Gene names	Zfyve21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

FYV1_HUMAN
θ value	4.1701e-05 (rank : 9)	NC score	0.367201 (rank : 12)
Query Neighborhood Hits	53	Target Neighborhood Hits	217	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

FYV1_MOUSE
θ value	4.1701e-05 (rank : 10)	NC score	0.367502 (rank : 11)
Query Neighborhood Hits	53	Target Neighborhood Hits	191	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

ZFY16_MOUSE
θ value	4.1701e-05 (rank : 11)	NC score	0.407023 (rank : 9)
Query Neighborhood Hits	53	Target Neighborhood Hits	108	Shared Neighborhood Hits	44
SwissProt Accessions	Q80U44, Q8BRD2, Q8CG97	Gene names	Zfyve16, Kiaa0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosomal- associated FYVE domain protein).

WDFY3_MOUSE
θ value	5.44631e-05 (rank : 12)	NC score	0.273880 (rank : 18)
Query Neighborhood Hits	53	Target Neighborhood Hits	332	Shared Neighborhood Hits	44
SwissProt Accessions	Q6VNB8, Q8C8H7	Gene names	Wdfy3
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Beach domain, WD repeat and FYVE domain-containing protein 1) (BWF1).

WDFY3_HUMAN
θ value	7.1131e-05 (rank : 13)	NC score	0.272528 (rank : 19)
Query Neighborhood Hits	53	Target Neighborhood Hits	348	Shared Neighborhood Hits	44
SwissProt Accessions	Q8IZQ1, Q4W5K5, Q6P0Q5, Q8N1T2, Q96BS7, Q96N85, Q9Y2J7	Gene names	WDFY3, KIAA0993
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy).

ZFYV9_HUMAN
θ value	7.1131e-05 (rank : 14)	NC score	0.418856 (rank : 8)
Query Neighborhood Hits	53	Target Neighborhood Hits	134	Shared Neighborhood Hits	45
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

EEA1_MOUSE
θ value	0.00020696 (rank : 15)	NC score	0.148455 (rank : 53)
Query Neighborhood Hits	53	Target Neighborhood Hits	1637	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

EEA1_HUMAN
θ value	0.000270298 (rank : 16)	NC score	0.136320 (rank : 54)
Query Neighborhood Hits	53	Target Neighborhood Hits	1796	Shared Neighborhood Hits	44
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

ZFY16_HUMAN
θ value	0.00035302 (rank : 17)	NC score	0.399661 (rank : 10)
Query Neighborhood Hits	53	Target Neighborhood Hits	125	Shared Neighborhood Hits	44
SwissProt Accessions	Q7Z3T8, O15023, Q7LAU7, Q86T69, Q8N5L3, Q8NEK3	Gene names	ZFYVE16, KIAA0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome- associated FYVE domain protein).

ANFY1_MOUSE
θ value	0.000786445 (rank : 18)	NC score	0.174003 (rank : 44)
Query Neighborhood Hits	53	Target Neighborhood Hits	480	Shared Neighborhood Hits	44
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

RUFY1_HUMAN
θ value	0.00102713 (rank : 19)	NC score	0.245438 (rank : 25)
Query Neighborhood Hits	53	Target Neighborhood Hits	848	Shared Neighborhood Hits	44
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

RUFY1_MOUSE
θ value	0.00134147 (rank : 20)	NC score	0.249765 (rank : 23)
Query Neighborhood Hits	53	Target Neighborhood Hits	765	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

RUFY2_HUMAN
θ value	0.00509761 (rank : 21)	NC score	0.190623 (rank : 38)
Query Neighborhood Hits	53	Target Neighborhood Hits	1208	Shared Neighborhood Hits	44
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

RUFY2_MOUSE
θ value	0.00509761 (rank : 22)	NC score	0.239648 (rank : 27)
Query Neighborhood Hits	53	Target Neighborhood Hits	820	Shared Neighborhood Hits	44
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

ANFY1_HUMAN
θ value	0.00665767 (rank : 23)	NC score	0.167183 (rank : 45)
Query Neighborhood Hits	53	Target Neighborhood Hits	480	Shared Neighborhood Hits	42
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ZFYV1_HUMAN
θ value	0.0148317 (rank : 24)	NC score	0.343171 (rank : 13)
Query Neighborhood Hits	53	Target Neighborhood Hits	166	Shared Neighborhood Hits	44
SwissProt Accessions	Q9HBF4, Q8WYX7, Q96K57, Q9BXP9, Q9HCI3	Gene names	ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (Tandem FYVE fingers-1) (SR3).

FGD1_MOUSE
θ value	0.0330416 (rank : 25)	NC score	0.198782 (rank : 33)
Query Neighborhood Hits	53	Target Neighborhood Hits	387	Shared Neighborhood Hits	42
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD3_MOUSE
θ value	0.0431538 (rank : 26)	NC score	0.181917 (rank : 40)
Query Neighborhood Hits	53	Target Neighborhood Hits	257	Shared Neighborhood Hits	42
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

HGS_MOUSE
θ value	0.0563607 (rank : 27)	NC score	0.294640 (rank : 15)
Query Neighborhood Hits	53	Target Neighborhood Hits	589	Shared Neighborhood Hits	44
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

ZFYV1_MOUSE
θ value	0.0563607 (rank : 28)	NC score	0.335015 (rank : 14)
Query Neighborhood Hits	53	Target Neighborhood Hits	153	Shared Neighborhood Hits	44
SwissProt Accessions	Q810J8	Gene names	Zfyve1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1.

FGD3_HUMAN
θ value	0.0736092 (rank : 29)	NC score	0.198470 (rank : 34)
Query Neighborhood Hits	53	Target Neighborhood Hits	249	Shared Neighborhood Hits	45
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

FGD1_HUMAN
θ value	0.0961366 (rank : 30)	NC score	0.196780 (rank : 36)
Query Neighborhood Hits	53	Target Neighborhood Hits	367	Shared Neighborhood Hits	42
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD5_MOUSE
θ value	0.0961366 (rank : 31)	NC score	0.243127 (rank : 26)
Query Neighborhood Hits	53	Target Neighborhood Hits	170	Shared Neighborhood Hits	44
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

FYCO1_MOUSE
θ value	0.0961366 (rank : 32)	NC score	0.149028 (rank : 52)
Query Neighborhood Hits	53	Target Neighborhood Hits	1059	Shared Neighborhood Hits	40
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

HGS_HUMAN
θ value	0.0961366 (rank : 33)	NC score	0.294165 (rank : 16)
Query Neighborhood Hits	53	Target Neighborhood Hits	517	Shared Neighborhood Hits	44
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

RNF34_MOUSE
θ value	0.163984 (rank : 34)	NC score	0.184220 (rank : 39)
Query Neighborhood Hits	53	Target Neighborhood Hits	160	Shared Neighborhood Hits	33
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

RNF34_HUMAN
θ value	0.21417 (rank : 35)	NC score	0.179833 (rank : 41)
Query Neighborhood Hits	53	Target Neighborhood Hits	153	Shared Neighborhood Hits	33
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

FYCO1_HUMAN
θ value	0.279714 (rank : 36)	NC score	0.151193 (rank : 48)
Query Neighborhood Hits	53	Target Neighborhood Hits	1149	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

FGD5_HUMAN
θ value	0.47712 (rank : 37)	NC score	0.229727 (rank : 31)
Query Neighborhood Hits	53	Target Neighborhood Hits	235	Shared Neighborhood Hits	45
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

MYRIP_MOUSE
θ value	0.47712 (rank : 38)	NC score	0.078287 (rank : 58)
Query Neighborhood Hits	53	Target Neighborhood Hits	207	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K3I4, Q8CFC0, Q8K4H5	Gene names	Myrip, Slac2c
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

FGD6_MOUSE
θ value	0.62314 (rank : 39)	NC score	0.223753 (rank : 32)
Query Neighborhood Hits	53	Target Neighborhood Hits	282	Shared Neighborhood Hits	41
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

RFFL_MOUSE
θ value	0.813845 (rank : 40)	NC score	0.160313 (rank : 46)
Query Neighborhood Hits	53	Target Neighborhood Hits	145	Shared Neighborhood Hits	34
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

RFFL_HUMAN
θ value	1.06291 (rank : 41)	NC score	0.152097 (rank : 47)
Query Neighborhood Hits	53	Target Neighborhood Hits	175	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

FGD6_HUMAN
θ value	1.38821 (rank : 42)	NC score	0.230571 (rank : 30)
Query Neighborhood Hits	53	Target Neighborhood Hits	237	Shared Neighborhood Hits	41
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

MYRIP_HUMAN
θ value	1.81305 (rank : 43)	NC score	0.067703 (rank : 59)
Query Neighborhood Hits	53	Target Neighborhood Hits	269	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

RBNS5_HUMAN
θ value	3.0926 (rank : 44)	NC score	0.238486 (rank : 28)
Query Neighborhood Hits	53	Target Neighborhood Hits	242	Shared Neighborhood Hits	39
SwissProt Accessions	Q9H1K0, Q3KP30, Q59EY8, Q8NAQ1	Gene names	ZFYVE20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20) (110 kDa protein).

RBNS5_MOUSE
θ value	3.0926 (rank : 45)	NC score	0.236059 (rank : 29)
Query Neighborhood Hits	53	Target Neighborhood Hits	266	Shared Neighborhood Hits	39
SwissProt Accessions	Q80Y56, Q8K0L6, Q9CTW0	Gene names	Zfyve20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20).

SMG5_HUMAN
θ value	4.03905 (rank : 46)	NC score	0.027898 (rank : 61)
Query Neighborhood Hits	53	Target Neighborhood Hits	180	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPR3, Q5QJE7, Q8IXC0, Q8IY09, Q96IJ7	Gene names	SMG5, EST1B, KIAA1089
Domain Architecture	No domain graphic available
Description	Protein SMG5 (SMG-5 homolog) (EST1-like protein B) (LPTS-interacting protein) (LPTS-RP1).

ZN558_HUMAN
θ value	4.03905 (rank : 47)	NC score	-0.000296 (rank : 67)
Query Neighborhood Hits	53	Target Neighborhood Hits	748	Shared Neighborhood Hits	4
SwissProt Accessions	Q96NG5	Gene names	ZNF558
Domain Architecture	No domain graphic available
Description	Zinc finger protein 558.

HIC2_MOUSE
θ value	5.27518 (rank : 48)	NC score	-0.000067 (rank : 66)
Query Neighborhood Hits	53	Target Neighborhood Hits	821	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JLZ6, Q3U030, Q3ULP4, Q5K036, Q8BSZ9, Q8C3T5	Gene names	Hic2, Kiaa1020
Domain Architecture
Description	Hypermethylated in cancer 2 protein (Hic-2).

EGFL8_HUMAN
θ value	6.88961 (rank : 49)	NC score	0.007646 (rank : 64)
Query Neighborhood Hits	53	Target Neighborhood Hits	270	Shared Neighborhood Hits	2
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

GON4L_HUMAN
θ value	6.88961 (rank : 50)	NC score	0.012989 (rank : 63)
Query Neighborhood Hits	53	Target Neighborhood Hits	555	Shared Neighborhood Hits	5
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

SMG5_MOUSE
θ value	6.88961 (rank : 51)	NC score	0.026997 (rank : 62)
Query Neighborhood Hits	53	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZPY2, Q497S2, Q8R3S4	Gene names	Smg5, Est1b, Kiaa1089
Domain Architecture	No domain graphic available
Description	Protein SMG5 (SMG-5 homolog) (EST1-like protein B).

C5AR_MOUSE
θ value	8.99809 (rank : 52)	NC score	0.001534 (rank : 65)
Query Neighborhood Hits	53	Target Neighborhood Hits	653	Shared Neighborhood Hits	3
SwissProt Accessions	P30993	Gene names	C5ar1, C5ar, C5r1
Domain Architecture
Description	C5a anaphylatoxin chemotactic receptor (C5a-R) (C5aR) (CD88 antigen).

FGD2_HUMAN
θ value	8.99809 (rank : 53)	NC score	0.197358 (rank : 35)
Query Neighborhood Hits	53	Target Neighborhood Hits	151	Shared Neighborhood Hits	42
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

CJ064_HUMAN
θ value	θ > 10 (rank : 54)	NC score	0.088599 (rank : 56)
Query Neighborhood Hits	53	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZS81, Q8N4A3	Gene names	C10orf64
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf64.

FGD2_MOUSE
θ value	θ > 10 (rank : 55)	NC score	0.191968 (rank : 37)
Query Neighborhood Hits	53	Target Neighborhood Hits	163	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

FGD4_HUMAN
θ value	θ > 10 (rank : 56)	NC score	0.177739 (rank : 42)
Query Neighborhood Hits	53	Target Neighborhood Hits	219	Shared Neighborhood Hits	40
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

FGD4_MOUSE
θ value	θ > 10 (rank : 57)	NC score	0.177161 (rank : 43)
Query Neighborhood Hits	53	Target Neighborhood Hits	227	Shared Neighborhood Hits	40
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

NBEAL_HUMAN
θ value	θ > 10 (rank : 58)	NC score	0.051717 (rank : 60)
Query Neighborhood Hits	53	Target Neighborhood Hits	200	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZS30, Q6Y876, Q6ZQY5, Q96Q30	Gene names	NBEAL1, ALS2CR17
Domain Architecture	No domain graphic available
Description	Neurobeachin-like 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein).

PKHF1_HUMAN
θ value	θ > 10 (rank : 59)	NC score	0.251061 (rank : 22)
Query Neighborhood Hits	53	Target Neighborhood Hits	76	Shared Neighborhood Hits	40
SwissProt Accessions	Q96S99, Q96K11, Q9BUB9	Gene names	PLEKHF1, APPD, LAPF, ZFYVE15
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (PH and FYVE domain-containing protein 1) (Phafin-1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains) (Apoptosis-inducing protein) (Zinc finger FYVE domain-containing protein 15).

PKHF1_MOUSE
θ value	θ > 10 (rank : 60)	NC score	0.248883 (rank : 24)
Query Neighborhood Hits	53	Target Neighborhood Hits	80	Shared Neighborhood Hits	41
SwissProt Accessions	Q3TB82, Q99M16	Gene names	Plekhf1, Lapf
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains).

PKHF2_HUMAN
θ value	θ > 10 (rank : 61)	NC score	0.256845 (rank : 21)
Query Neighborhood Hits	53	Target Neighborhood Hits	75	Shared Neighborhood Hits	39
SwissProt Accessions	Q9H8W4	Gene names	PLEKHF2, ZFYVE18
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2) (PH and FYVE domain-containing protein 2) (Phafin-2) (Zinc finger FYVE domain-containing protein 18).

PKHF2_MOUSE
θ value	θ > 10 (rank : 62)	NC score	0.257597 (rank : 20)
Query Neighborhood Hits	53	Target Neighborhood Hits	77	Shared Neighborhood Hits	39
SwissProt Accessions	Q91WB4	Gene names	Plekhf2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2).

RUFY3_HUMAN
θ value	θ > 10 (rank : 63)	NC score	0.088534 (rank : 57)
Query Neighborhood Hits	53	Target Neighborhood Hits	594	Shared Neighborhood Hits	8
SwissProt Accessions	Q7L099, O94948, Q9UI00	Gene names	RUFY3, KIAA0871
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

RUFY3_MOUSE
θ value	θ > 10 (rank : 64)	NC score	0.089332 (rank : 55)
Query Neighborhood Hits	53	Target Neighborhood Hits	579	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D394, Q3U348, Q3UF96, Q6PE64, Q8VD10	Gene names	Rufy3, D5Bwg0860e, Ripx
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

WDFY1_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.151187 (rank : 49)
Query Neighborhood Hits	53	Target Neighborhood Hits	305	Shared Neighborhood Hits	38
SwissProt Accessions	Q8IWB7, Q9H9D5, Q9P2B3	Gene names	WDFY1, KIAA1435, WDF1, ZFYVE17
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 1 (WD40- and FYVE domain- containing protein 1) (Phosphoinositide-binding protein 1) (FENS-1) (Zinc finger FYVE domain-containing protein 17).

WDFY2_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.149805 (rank : 51)
Query Neighborhood Hits	53	Target Neighborhood Hits	332	Shared Neighborhood Hits	38
SwissProt Accessions	Q96P53, Q96CS1	Gene names	WDFY2, WDF2, ZFYVE22
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2) (Zinc finger FYVE domain-containing protein 22).

WDFY2_MOUSE
θ value	θ > 10 (rank : 67)	NC score	0.151025 (rank : 50)
Query Neighborhood Hits	53	Target Neighborhood Hits	337	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BUB4	Gene names	Wdfy2
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2).

Hits sorted by NC score

ZFY27_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	53	Target Neighborhood Hits	53	Shared Neighborhood Hits	53
SwissProt Accessions	Q3TXX3, Q8CFP8	Gene names	Zfyve27
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 27.

ZFY27_HUMAN
NC score	0.994712 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	53	Target Neighborhood Hits	64	Shared Neighborhood Hits	48
SwissProt Accessions	Q5T4F4, Q5T4F1, Q5T4F2, Q5T4F3, Q8N1K0, Q8N6D6, Q8NCA0, Q8NDE4, Q96M08	Gene names	ZFYVE27
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 27.

ZFY21_HUMAN
NC score	0.485593 (rank : 3)	θ value	1.87187e-05 (rank : 7)
Query Neighborhood Hits	53	Target Neighborhood Hits	72	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BQ24, Q86T05, Q96LT1	Gene names	ZFYVE21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

ZFY21_MOUSE
NC score	0.484103 (rank : 4)	θ value	3.19293e-05 (rank : 8)
Query Neighborhood Hits	53	Target Neighborhood Hits	72	Shared Neighborhood Hits	44
SwissProt Accessions	Q8VCM3, Q9D1E2	Gene names	Zfyve21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

ZFY28_HUMAN
NC score	0.471241 (rank : 5)	θ value	6.43352e-06 (rank : 6)
Query Neighborhood Hits	53	Target Neighborhood Hits	152	Shared Neighborhood Hits	44
SwissProt Accessions	Q9HCC9	Gene names	ZFYVE28, KIAA1643
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 28.

ZFY19_MOUSE
NC score	0.456033 (rank : 6)	θ value	6.43352e-06 (rank : 5)
Query Neighborhood Hits	53	Target Neighborhood Hits	143	Shared Neighborhood Hits	42
SwissProt Accessions	Q9DAZ9, Q8VCV7	Gene names	Zfyve19
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19.

ZFY19_HUMAN
NC score	0.449883 (rank : 7)	θ value	2.21117e-06 (rank : 3)
Query Neighborhood Hits	53	Target Neighborhood Hits	206	Shared Neighborhood Hits	41
SwissProt Accessions	Q96K21, Q86WC2, Q8WU96	Gene names	ZFYVE19, MPFYVE
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19 (MLL partner containing FYVE domain).

ZFYV9_HUMAN
NC score	0.418856 (rank : 8)	θ value	7.1131e-05 (rank : 14)
Query Neighborhood Hits	53	Target Neighborhood Hits	134	Shared Neighborhood Hits	45
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

ZFY16_MOUSE
NC score	0.407023 (rank : 9)	θ value	4.1701e-05 (rank : 11)
Query Neighborhood Hits	53	Target Neighborhood Hits	108	Shared Neighborhood Hits	44
SwissProt Accessions	Q80U44, Q8BRD2, Q8CG97	Gene names	Zfyve16, Kiaa0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosomal- associated FYVE domain protein).

ZFY16_HUMAN
NC score	0.399661 (rank : 10)	θ value	0.00035302 (rank : 17)
Query Neighborhood Hits	53	Target Neighborhood Hits	125	Shared Neighborhood Hits	44
SwissProt Accessions	Q7Z3T8, O15023, Q7LAU7, Q86T69, Q8N5L3, Q8NEK3	Gene names	ZFYVE16, KIAA0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome- associated FYVE domain protein).

FYV1_MOUSE
NC score	0.367502 (rank : 11)	θ value	4.1701e-05 (rank : 10)
Query Neighborhood Hits	53	Target Neighborhood Hits	191	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

FYV1_HUMAN
NC score	0.367201 (rank : 12)	θ value	4.1701e-05 (rank : 9)
Query Neighborhood Hits	53	Target Neighborhood Hits	217	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

ZFYV1_HUMAN
NC score	0.343171 (rank : 13)	θ value	0.0148317 (rank : 24)
Query Neighborhood Hits	53	Target Neighborhood Hits	166	Shared Neighborhood Hits	44
SwissProt Accessions	Q9HBF4, Q8WYX7, Q96K57, Q9BXP9, Q9HCI3	Gene names	ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (Tandem FYVE fingers-1) (SR3).

ZFYV1_MOUSE
NC score	0.335015 (rank : 14)	θ value	0.0563607 (rank : 28)
Query Neighborhood Hits	53	Target Neighborhood Hits	153	Shared Neighborhood Hits	44
SwissProt Accessions	Q810J8	Gene names	Zfyve1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1.

HGS_MOUSE
NC score	0.294640 (rank : 15)	θ value	0.0563607 (rank : 27)
Query Neighborhood Hits	53	Target Neighborhood Hits	589	Shared Neighborhood Hits	44
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

HGS_HUMAN
NC score	0.294165 (rank : 16)	θ value	0.0961366 (rank : 33)
Query Neighborhood Hits	53	Target Neighborhood Hits	517	Shared Neighborhood Hits	44
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

MTMR3_HUMAN
NC score	0.285604 (rank : 17)	θ value	2.88788e-06 (rank : 4)
Query Neighborhood Hits	53	Target Neighborhood Hits	163	Shared Neighborhood Hits	45
SwissProt Accessions	Q13615, Q9NYN5, Q9NYN6, Q9UDX6, Q9UEG3	Gene names	MTMR3, KIAA0371, ZFYVE10
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Zinc finger FYVE domain-containing protein 10).

WDFY3_MOUSE
NC score	0.273880 (rank : 18)	θ value	5.44631e-05 (rank : 12)
Query Neighborhood Hits	53	Target Neighborhood Hits	332	Shared Neighborhood Hits	44
SwissProt Accessions	Q6VNB8, Q8C8H7	Gene names	Wdfy3
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Beach domain, WD repeat and FYVE domain-containing protein 1) (BWF1).

WDFY3_HUMAN
NC score	0.272528 (rank : 19)	θ value	7.1131e-05 (rank : 13)
Query Neighborhood Hits	53	Target Neighborhood Hits	348	Shared Neighborhood Hits	44
SwissProt Accessions	Q8IZQ1, Q4W5K5, Q6P0Q5, Q8N1T2, Q96BS7, Q96N85, Q9Y2J7	Gene names	WDFY3, KIAA0993
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy).

PKHF2_MOUSE
NC score	0.257597 (rank : 20)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	53	Target Neighborhood Hits	77	Shared Neighborhood Hits	39
SwissProt Accessions	Q91WB4	Gene names	Plekhf2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2).

PKHF2_HUMAN
NC score	0.256845 (rank : 21)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	53	Target Neighborhood Hits	75	Shared Neighborhood Hits	39
SwissProt Accessions	Q9H8W4	Gene names	PLEKHF2, ZFYVE18
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2) (PH and FYVE domain-containing protein 2) (Phafin-2) (Zinc finger FYVE domain-containing protein 18).

PKHF1_HUMAN
NC score	0.251061 (rank : 22)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	53	Target Neighborhood Hits	76	Shared Neighborhood Hits	40
SwissProt Accessions	Q96S99, Q96K11, Q9BUB9	Gene names	PLEKHF1, APPD, LAPF, ZFYVE15
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (PH and FYVE domain-containing protein 1) (Phafin-1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains) (Apoptosis-inducing protein) (Zinc finger FYVE domain-containing protein 15).

RUFY1_MOUSE
NC score	0.249765 (rank : 23)	θ value	0.00134147 (rank : 20)
Query Neighborhood Hits	53	Target Neighborhood Hits	765	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

PKHF1_MOUSE
NC score	0.248883 (rank : 24)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	53	Target Neighborhood Hits	80	Shared Neighborhood Hits	41
SwissProt Accessions	Q3TB82, Q99M16	Gene names	Plekhf1, Lapf
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains).

RUFY1_HUMAN
NC score	0.245438 (rank : 25)	θ value	0.00102713 (rank : 19)
Query Neighborhood Hits	53	Target Neighborhood Hits	848	Shared Neighborhood Hits	44
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

FGD5_MOUSE
NC score	0.243127 (rank : 26)	θ value	0.0961366 (rank : 31)
Query Neighborhood Hits	53	Target Neighborhood Hits	170	Shared Neighborhood Hits	44
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

RUFY2_MOUSE
NC score	0.239648 (rank : 27)	θ value	0.00509761 (rank : 22)
Query Neighborhood Hits	53	Target Neighborhood Hits	820	Shared Neighborhood Hits	44
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

RBNS5_HUMAN
NC score	0.238486 (rank : 28)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	53	Target Neighborhood Hits	242	Shared Neighborhood Hits	39
SwissProt Accessions	Q9H1K0, Q3KP30, Q59EY8, Q8NAQ1	Gene names	ZFYVE20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20) (110 kDa protein).

RBNS5_MOUSE
NC score	0.236059 (rank : 29)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	53	Target Neighborhood Hits	266	Shared Neighborhood Hits	39
SwissProt Accessions	Q80Y56, Q8K0L6, Q9CTW0	Gene names	Zfyve20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20).

FGD6_HUMAN
NC score	0.230571 (rank : 30)	θ value	1.38821 (rank : 42)
Query Neighborhood Hits	53	Target Neighborhood Hits	237	Shared Neighborhood Hits	41
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

FGD5_HUMAN
NC score	0.229727 (rank : 31)	θ value	0.47712 (rank : 37)
Query Neighborhood Hits	53	Target Neighborhood Hits	235	Shared Neighborhood Hits	45
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

FGD6_MOUSE
NC score	0.223753 (rank : 32)	θ value	0.62314 (rank : 39)
Query Neighborhood Hits	53	Target Neighborhood Hits	282	Shared Neighborhood Hits	41
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

FGD1_MOUSE
NC score	0.198782 (rank : 33)	θ value	0.0330416 (rank : 25)
Query Neighborhood Hits	53	Target Neighborhood Hits	387	Shared Neighborhood Hits	42
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD3_HUMAN
NC score	0.198470 (rank : 34)	θ value	0.0736092 (rank : 29)
Query Neighborhood Hits	53	Target Neighborhood Hits	249	Shared Neighborhood Hits	45
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

FGD2_HUMAN
NC score	0.197358 (rank : 35)	θ value	8.99809 (rank : 53)
Query Neighborhood Hits	53	Target Neighborhood Hits	151	Shared Neighborhood Hits	42
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

FGD1_HUMAN
NC score	0.196780 (rank : 36)	θ value	0.0961366 (rank : 30)
Query Neighborhood Hits	53	Target Neighborhood Hits	367	Shared Neighborhood Hits	42
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD2_MOUSE
NC score	0.191968 (rank : 37)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	53	Target Neighborhood Hits	163	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

RUFY2_HUMAN
NC score	0.190623 (rank : 38)	θ value	0.00509761 (rank : 21)
Query Neighborhood Hits	53	Target Neighborhood Hits	1208	Shared Neighborhood Hits	44
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

RNF34_MOUSE
NC score	0.184220 (rank : 39)	θ value	0.163984 (rank : 34)
Query Neighborhood Hits	53	Target Neighborhood Hits	160	Shared Neighborhood Hits	33
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

FGD3_MOUSE
NC score	0.181917 (rank : 40)	θ value	0.0431538 (rank : 26)
Query Neighborhood Hits	53	Target Neighborhood Hits	257	Shared Neighborhood Hits	42
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

RNF34_HUMAN
NC score	0.179833 (rank : 41)	θ value	0.21417 (rank : 35)
Query Neighborhood Hits	53	Target Neighborhood Hits	153	Shared Neighborhood Hits	33
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

FGD4_HUMAN
NC score	0.177739 (rank : 42)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	53	Target Neighborhood Hits	219	Shared Neighborhood Hits	40
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

FGD4_MOUSE
NC score	0.177161 (rank : 43)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	53	Target Neighborhood Hits	227	Shared Neighborhood Hits	40
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

ANFY1_MOUSE
NC score	0.174003 (rank : 44)	θ value	0.000786445 (rank : 18)
Query Neighborhood Hits	53	Target Neighborhood Hits	480	Shared Neighborhood Hits	44
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANFY1_HUMAN
NC score	0.167183 (rank : 45)	θ value	0.00665767 (rank : 23)
Query Neighborhood Hits	53	Target Neighborhood Hits	480	Shared Neighborhood Hits	42
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

RFFL_MOUSE
NC score	0.160313 (rank : 46)	θ value	0.813845 (rank : 40)
Query Neighborhood Hits	53	Target Neighborhood Hits	145	Shared Neighborhood Hits	34
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

RFFL_HUMAN
NC score	0.152097 (rank : 47)	θ value	1.06291 (rank : 41)
Query Neighborhood Hits	53	Target Neighborhood Hits	175	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

FYCO1_HUMAN
NC score	0.151193 (rank : 48)	θ value	0.279714 (rank : 36)
Query Neighborhood Hits	53	Target Neighborhood Hits	1149	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

WDFY1_HUMAN
NC score	0.151187 (rank : 49)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	53	Target Neighborhood Hits	305	Shared Neighborhood Hits	38
SwissProt Accessions	Q8IWB7, Q9H9D5, Q9P2B3	Gene names	WDFY1, KIAA1435, WDF1, ZFYVE17
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 1 (WD40- and FYVE domain- containing protein 1) (Phosphoinositide-binding protein 1) (FENS-1) (Zinc finger FYVE domain-containing protein 17).

WDFY2_MOUSE
NC score	0.151025 (rank : 50)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	53	Target Neighborhood Hits	337	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BUB4	Gene names	Wdfy2
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2).

WDFY2_HUMAN
NC score	0.149805 (rank : 51)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	53	Target Neighborhood Hits	332	Shared Neighborhood Hits	38
SwissProt Accessions	Q96P53, Q96CS1	Gene names	WDFY2, WDF2, ZFYVE22
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2) (Zinc finger FYVE domain-containing protein 22).

FYCO1_MOUSE
NC score	0.149028 (rank : 52)	θ value	0.0961366 (rank : 32)
Query Neighborhood Hits	53	Target Neighborhood Hits	1059	Shared Neighborhood Hits	40
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

EEA1_MOUSE
NC score	0.148455 (rank : 53)	θ value	0.00020696 (rank : 15)
Query Neighborhood Hits	53	Target Neighborhood Hits	1637	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

EEA1_HUMAN
NC score	0.136320 (rank : 54)	θ value	0.000270298 (rank : 16)
Query Neighborhood Hits	53	Target Neighborhood Hits	1796	Shared Neighborhood Hits	44
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

RUFY3_MOUSE
NC score	0.089332 (rank : 55)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	53	Target Neighborhood Hits	579	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D394, Q3U348, Q3UF96, Q6PE64, Q8VD10	Gene names	Rufy3, D5Bwg0860e, Ripx
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

CJ064_HUMAN
NC score	0.088599 (rank : 56)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	53	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZS81, Q8N4A3	Gene names	C10orf64
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf64.

RUFY3_HUMAN
NC score	0.088534 (rank : 57)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	53	Target Neighborhood Hits	594	Shared Neighborhood Hits	8
SwissProt Accessions	Q7L099, O94948, Q9UI00	Gene names	RUFY3, KIAA0871
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

MYRIP_MOUSE
NC score	0.078287 (rank : 58)	θ value	0.47712 (rank : 38)
Query Neighborhood Hits	53	Target Neighborhood Hits	207	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K3I4, Q8CFC0, Q8K4H5	Gene names	Myrip, Slac2c
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

MYRIP_HUMAN
NC score	0.067703 (rank : 59)	θ value	1.81305 (rank : 43)
Query Neighborhood Hits	53	Target Neighborhood Hits	269	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

NBEAL_HUMAN
NC score	0.051717 (rank : 60)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	53	Target Neighborhood Hits	200	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZS30, Q6Y876, Q6ZQY5, Q96Q30	Gene names	NBEAL1, ALS2CR17
Domain Architecture	No domain graphic available
Description	Neurobeachin-like 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein).

SMG5_HUMAN
NC score	0.027898 (rank : 61)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	53	Target Neighborhood Hits	180	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPR3, Q5QJE7, Q8IXC0, Q8IY09, Q96IJ7	Gene names	SMG5, EST1B, KIAA1089
Domain Architecture	No domain graphic available
Description	Protein SMG5 (SMG-5 homolog) (EST1-like protein B) (LPTS-interacting protein) (LPTS-RP1).

SMG5_MOUSE
NC score	0.026997 (rank : 62)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	53	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZPY2, Q497S2, Q8R3S4	Gene names	Smg5, Est1b, Kiaa1089
Domain Architecture	No domain graphic available
Description	Protein SMG5 (SMG-5 homolog) (EST1-like protein B).

GON4L_HUMAN
NC score	0.012989 (rank : 63)	θ value	6.88961 (rank : 50)
Query Neighborhood Hits	53	Target Neighborhood Hits	555	Shared Neighborhood Hits	5
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

EGFL8_HUMAN
NC score	0.007646 (rank : 64)	θ value	6.88961 (rank : 49)
Query Neighborhood Hits	53	Target Neighborhood Hits	270	Shared Neighborhood Hits	2
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

C5AR_MOUSE
NC score	0.001534 (rank : 65)	θ value	8.99809 (rank : 52)
Query Neighborhood Hits	53	Target Neighborhood Hits	653	Shared Neighborhood Hits	3
SwissProt Accessions	P30993	Gene names	C5ar1, C5ar, C5r1
Domain Architecture
Description	C5a anaphylatoxin chemotactic receptor (C5a-R) (C5aR) (CD88 antigen).

HIC2_MOUSE
NC score	-0.000067 (rank : 66)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	53	Target Neighborhood Hits	821	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JLZ6, Q3U030, Q3ULP4, Q5K036, Q8BSZ9, Q8C3T5	Gene names	Hic2, Kiaa1020
Domain Architecture
Description	Hypermethylated in cancer 2 protein (Hic-2).

ZN558_HUMAN
NC score	-0.000296 (rank : 67)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	53	Target Neighborhood Hits	748	Shared Neighborhood Hits	4
SwissProt Accessions	Q96NG5	Gene names	ZNF558
Domain Architecture	No domain graphic available
Description	Zinc finger protein 558.