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Network neighborhood for query Sequence : SEPT4_HUMAN

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SEPT4_HUMAN
SwissProt Accessions	O43236, Q9UM58	Gene names	SEPT4, PNUTL2
Domain Architecture
Description	Septin-4 (Peanut-like protein 2) (Brain protein H5) (Cell division control-related protein 2) (hCDCREL-2) (Bradeion beta) (CE5B3 beta) (Cerebral protein 7).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SEPT4_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	44	Target Neighborhood Hits	44	Shared Neighborhood Hits	44
SwissProt Accessions	O43236, Q9UM58	Gene names	SEPT4, PNUTL2
Domain Architecture
Description	Septin-4 (Peanut-like protein 2) (Brain protein H5) (Cell division control-related protein 2) (hCDCREL-2) (Bradeion beta) (CE5B3 beta) (Cerebral protein 7).

SEPT4_MOUSE
θ value	0 (rank : 2)	NC score	0.999401 (rank : 2)
Query Neighborhood Hits	44	Target Neighborhood Hits	38	Shared Neighborhood Hits	30
SwissProt Accessions	P28661, Q5ND15	Gene names	Sept4, Pnutl2
Domain Architecture
Description	Septin-4 (Peanut-like protein 2) (Brain protein H5).

SEPT5_HUMAN
θ value	1.91371e-159 (rank : 3)	NC score	0.996558 (rank : 3)
Query Neighborhood Hits	44	Target Neighborhood Hits	44	Shared Neighborhood Hits	22
SwissProt Accessions	Q99719, O15251	Gene names	SEPT5, PNUTL1
Domain Architecture
Description	Septin-5 (Peanut-like protein 1) (Cell division control-related protein 1) (CDCrel-1).

SEPT5_MOUSE
θ value	5.56804e-159 (rank : 4)	NC score	0.996408 (rank : 4)
Query Neighborhood Hits	44	Target Neighborhood Hits	44	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z2Q6, Q3UYG4, Q6PB74	Gene names	Sept5, Pnutl1
Domain Architecture	No domain graphic available
Description	Septin-5 (Peanut-like protein 1) (Cell division control-related protein 1) (CDCrel-1).

SEPT1_HUMAN
θ value	6.85399e-133 (rank : 5)	NC score	0.993676 (rank : 6)
Query Neighborhood Hits	44	Target Neighborhood Hits	65	Shared Neighborhood Hits	23
SwissProt Accessions	Q8WYJ6, Q8NEZ1, Q96EL4, Q9H285	Gene names	SEPT1, PNUTL3
Domain Architecture
Description	Septin-1 (LARP) (Serologically defined breast cancer antigen NY-BR- 24).

SEPT1_MOUSE
θ value	1.25199e-126 (rank : 6)	NC score	0.993894 (rank : 5)
Query Neighborhood Hits	44	Target Neighborhood Hits	58	Shared Neighborhood Hits	23
SwissProt Accessions	P42209	Gene names	Sept1, Diff6, Pnutl3
Domain Architecture
Description	Septin-1 (Differentiation protein 6) (Diff6 protein).

SEPT2_HUMAN
θ value	1.06234e-117 (rank : 7)	NC score	0.989376 (rank : 7)
Query Neighborhood Hits	44	Target Neighborhood Hits	101	Shared Neighborhood Hits	23
SwissProt Accessions	Q15019, Q14132, Q8IUK9, Q96CB0	Gene names	SEPT2, DIFF6, KIAA0158, NEDD5
Domain Architecture
Description	Septin-2 (Protein NEDD5).

SEPT2_MOUSE
θ value	1.38745e-117 (rank : 8)	NC score	0.989082 (rank : 8)
Query Neighborhood Hits	44	Target Neighborhood Hits	105	Shared Neighborhood Hits	23
SwissProt Accessions	P42208, Q3U9Y5	Gene names	Sept2, Nedd-5, Nedd5
Domain Architecture
Description	Septin-2 (Protein NEDD5) (Neural precursor cell expressed developmentally down-regulated protein 5).

SEPT7_HUMAN
θ value	1.59114e-105 (rank : 9)	NC score	0.947600 (rank : 14)
Query Neighborhood Hits	44	Target Neighborhood Hits	385	Shared Neighborhood Hits	24
SwissProt Accessions	Q16181, Q6NX50	Gene names	SEPT7, CDC10
Domain Architecture
Description	Septin-7 (CDC10 protein homolog).

SEPT7_MOUSE
θ value	1.59114e-105 (rank : 10)	NC score	0.950237 (rank : 11)
Query Neighborhood Hits	44	Target Neighborhood Hits	327	Shared Neighborhood Hits	24
SwissProt Accessions	O55131	Gene names	Sept7, Cdc10
Domain Architecture
Description	Septin-7 (CDC10 protein homolog).

SEPT3_HUMAN
θ value	2.38869e-85 (rank : 11)	NC score	0.980702 (rank : 9)
Query Neighborhood Hits	44	Target Neighborhood Hits	56	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UH03, Q6IBZ6, Q8N3P3	Gene names	SEPT3, SEP3
Domain Architecture
Description	Neuronal-specific septin-3.

SEPT9_HUMAN
θ value	4.50487e-84 (rank : 12)	NC score	0.888910 (rank : 22)
Query Neighborhood Hits	44	Target Neighborhood Hits	706	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

SEPT9_MOUSE
θ value	3.81361e-83 (rank : 13)	NC score	0.947608 (rank : 13)
Query Neighborhood Hits	44	Target Neighborhood Hits	238	Shared Neighborhood Hits	22
SwissProt Accessions	Q80UG5, Q3URP2, Q80TM7, Q9QYX9	Gene names	Sept9, Kiaa0991, Sint1
Domain Architecture	No domain graphic available
Description	Septin-9 (SL3-3 integration site 1 protein).

SEPT3_MOUSE
θ value	3.94648e-80 (rank : 14)	NC score	0.977279 (rank : 10)
Query Neighborhood Hits	44	Target Neighborhood Hits	56	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z1S5	Gene names	Sept3, Sep3
Domain Architecture
Description	Neuronal-specific septin-3.

SEP10_MOUSE
θ value	1.19101e-68 (rank : 15)	NC score	0.949646 (rank : 12)
Query Neighborhood Hits	44	Target Neighborhood Hits	145	Shared Neighborhood Hits	23
SwissProt Accessions	Q8C650, Q7TSA5	Gene names	Sept10
Domain Architecture	No domain graphic available
Description	Septin-10.

SEP11_HUMAN
θ value	2.93355e-67 (rank : 16)	NC score	0.927378 (rank : 19)
Query Neighborhood Hits	44	Target Neighborhood Hits	296	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NVA2, Q7L4N1	Gene names	SEPT11
Domain Architecture	No domain graphic available
Description	Septin-11.

SEP11_MOUSE
θ value	2.93355e-67 (rank : 17)	NC score	0.926656 (rank : 20)
Query Neighborhood Hits	44	Target Neighborhood Hits	300	Shared Neighborhood Hits	23
SwissProt Accessions	Q8C1B7, Q6P2K5, Q6P6I0	Gene names	Sept11, D5Ertd606e
Domain Architecture	No domain graphic available
Description	Septin-11.

SEP10_HUMAN
θ value	8.53533e-67 (rank : 18)	NC score	0.945508 (rank : 15)
Query Neighborhood Hits	44	Target Neighborhood Hits	161	Shared Neighborhood Hits	22
SwissProt Accessions	Q9P0V9, Q9HAH6	Gene names	SEPT10
Domain Architecture	No domain graphic available
Description	Septin-10.

SEPT6_HUMAN
θ value	1.90147e-66 (rank : 19)	NC score	0.937785 (rank : 16)
Query Neighborhood Hits	44	Target Neighborhood Hits	220	Shared Neighborhood Hits	23
SwissProt Accessions	Q14141, Q5JTK0, Q969W5, Q96A13, Q96GR1, Q96P86, Q96P87	Gene names	SEPT6, KIAA0128, SEP2
Domain Architecture
Description	Septin-6.

SEPT8_HUMAN
θ value	7.2256e-66 (rank : 20)	NC score	0.923812 (rank : 21)
Query Neighborhood Hits	44	Target Neighborhood Hits	290	Shared Neighborhood Hits	23
SwissProt Accessions	Q92599, Q8IX36, Q8IX37, Q9BVB3	Gene names	SEPT8, KIAA0202
Domain Architecture
Description	Septin-8.

SEPT8_MOUSE
θ value	7.2256e-66 (rank : 21)	NC score	0.931183 (rank : 18)
Query Neighborhood Hits	44	Target Neighborhood Hits	251	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CHH9, Q80YC7, Q9ESF7	Gene names	Sept8, Kiaa0202
Domain Architecture
Description	Septin-8.

SEPT6_MOUSE
θ value	1.6097e-65 (rank : 22)	NC score	0.934605 (rank : 17)
Query Neighborhood Hits	44	Target Neighborhood Hits	244	Shared Neighborhood Hits	23
SwissProt Accessions	Q9R1T4, Q91XH2, Q9CZ94	Gene names	Sept6
Domain Architecture
Description	Septin-6.

IQGA2_HUMAN
θ value	0.125558 (rank : 23)	NC score	0.022710 (rank : 23)
Query Neighborhood Hits	44	Target Neighborhood Hits	200	Shared Neighborhood Hits	4
SwissProt Accessions	Q13576	Gene names	IQGAP2
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP2.

GIT2_MOUSE
θ value	0.365318 (rank : 24)	NC score	0.012298 (rank : 27)
Query Neighborhood Hits	44	Target Neighborhood Hits	323	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

K1B11_MOUSE
θ value	0.813845 (rank : 25)	NC score	0.004415 (rank : 34)
Query Neighborhood Hits	44	Target Neighborhood Hits	180	Shared Neighborhood Hits	4
SwissProt Accessions	P15946	Gene names	Klk1b11, Klk-11, Klk11
Domain Architecture
Description	Kallikrein 1-related peptidase b11 precursor (EC 3.4.21.35) (Tissue kallikrein-11) (Glandular kallikrein K11) (mGK-11).

ES8L3_HUMAN
θ value	1.81305 (rank : 26)	NC score	0.008080 (rank : 31)
Query Neighborhood Hits	44	Target Neighborhood Hits	206	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TE67, Q5T8Q6, Q5T8Q7, Q5T8Q8, Q96E47, Q9H719	Gene names	EPS8L3, EPS8R3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

MTSS1_HUMAN
θ value	1.81305 (rank : 27)	NC score	0.010074 (rank : 28)
Query Neighborhood Hits	44	Target Neighborhood Hits	504	Shared Neighborhood Hits	5
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

GOGA2_HUMAN
θ value	3.0926 (rank : 28)	NC score	0.001517 (rank : 40)
Query Neighborhood Hits	44	Target Neighborhood Hits	856	Shared Neighborhood Hits	6
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

ACK1_MOUSE
θ value	6.88961 (rank : 29)	NC score	-0.002669 (rank : 44)
Query Neighborhood Hits	44	Target Neighborhood Hits	1080	Shared Neighborhood Hits	4
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

AKAP2_HUMAN
θ value	6.88961 (rank : 30)	NC score	0.012935 (rank : 25)
Query Neighborhood Hits	44	Target Neighborhood Hits	507	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

HXA1_MOUSE
θ value	6.88961 (rank : 31)	NC score	0.000975 (rank : 42)
Query Neighborhood Hits	44	Target Neighborhood Hits	341	Shared Neighborhood Hits	3
SwissProt Accessions	P09022, P15463	Gene names	Hoxa1, Era-1, Hox-1.6, Hoxa-1
Domain Architecture
Description	Homeobox protein Hox-A1 (Hox-1.6) (Homeotic protein ERA-1-993) (Early retinoic acid 1) (Homeoboxless protein ERA-1-399).

MDR1_MOUSE
θ value	6.88961 (rank : 32)	NC score	0.002235 (rank : 38)
Query Neighborhood Hits	44	Target Neighborhood Hits	105	Shared Neighborhood Hits	3
SwissProt Accessions	P06795	Gene names	Abcb1, Abcb1b, Mdr1, Mdr1b, Pgy1, Pgy1-1
Domain Architecture
Description	Multidrug resistance protein 1 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1) (P-glycoprotein 1) (CD243 antigen).

MLL2_HUMAN
θ value	6.88961 (rank : 33)	NC score	0.003853 (rank : 35)
Query Neighborhood Hits	44	Target Neighborhood Hits	1788	Shared Neighborhood Hits	9
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MY18A_MOUSE
θ value	6.88961 (rank : 34)	NC score	0.012793 (rank : 26)
Query Neighborhood Hits	44	Target Neighborhood Hits	1989	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

P3C2G_HUMAN
θ value	6.88961 (rank : 35)	NC score	0.003176 (rank : 36)
Query Neighborhood Hits	44	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	O75747	Gene names	PIK3C2G
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).

SYTL1_HUMAN
θ value	6.88961 (rank : 36)	NC score	0.006142 (rank : 32)
Query Neighborhood Hits	44	Target Neighborhood Hits	227	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IYJ3, Q96BB6, Q96GU6, Q96S89, Q96SI0	Gene names	SYTL1, SLP1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1) (SB146).

T2FA_HUMAN
θ value	6.88961 (rank : 37)	NC score	0.021492 (rank : 24)
Query Neighborhood Hits	44	Target Neighborhood Hits	228	Shared Neighborhood Hits	5
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

TMF1_HUMAN
θ value	6.88961 (rank : 38)	NC score	0.004635 (rank : 33)
Query Neighborhood Hits	44	Target Neighborhood Hits	987	Shared Neighborhood Hits	9
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

ATRX_HUMAN
θ value	8.99809 (rank : 39)	NC score	0.001697 (rank : 39)
Query Neighborhood Hits	44	Target Neighborhood Hits	842	Shared Neighborhood Hits	5
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

CEP57_MOUSE
θ value	8.99809 (rank : 40)	NC score	0.002733 (rank : 37)
Query Neighborhood Hits	44	Target Neighborhood Hits	580	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

COR2A_HUMAN
θ value	8.99809 (rank : 41)	NC score	0.001111 (rank : 41)
Query Neighborhood Hits	44	Target Neighborhood Hits	214	Shared Neighborhood Hits	2
SwissProt Accessions	Q92828, Q92829, Q9BWS5	Gene names	CORO2A, IR10, WDR2
Domain Architecture
Description	Coronin-2A (WD repeat-containing protein 2) (IR10).

K1KB5_MOUSE
θ value	8.99809 (rank : 42)	NC score	0.000861 (rank : 43)
Query Neighborhood Hits	44	Target Neighborhood Hits	177	Shared Neighborhood Hits	3
SwissProt Accessions	P15945, Q52KM1, Q565D7	Gene names	Klk1b5, Klk-5, Klk5
Domain Architecture
Description	Kallikrein 1-related peptidase b5 precursor (EC 3.4.21.35) (Glandular kallikrein K5) (Tissue kallikrein-5) (mGK-5).

SPF45_HUMAN
θ value	8.99809 (rank : 43)	NC score	0.008580 (rank : 29)
Query Neighborhood Hits	44	Target Neighborhood Hits	94	Shared Neighborhood Hits	3
SwissProt Accessions	Q96I25, Q96GY6	Gene names	RBM17, SPF45
Domain Architecture
Description	Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17).

SPF45_MOUSE
θ value	8.99809 (rank : 44)	NC score	0.008515 (rank : 30)
Query Neighborhood Hits	44	Target Neighborhood Hits	95	Shared Neighborhood Hits	3
SwissProt Accessions	Q8JZX4, O75939	Gene names	Rbm17, Spf45
Domain Architecture
Description	Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17).

Hits sorted by NC score

SEPT4_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	44	Target Neighborhood Hits	44	Shared Neighborhood Hits	44
SwissProt Accessions	O43236, Q9UM58	Gene names	SEPT4, PNUTL2
Domain Architecture
Description	Septin-4 (Peanut-like protein 2) (Brain protein H5) (Cell division control-related protein 2) (hCDCREL-2) (Bradeion beta) (CE5B3 beta) (Cerebral protein 7).

SEPT4_MOUSE
NC score	0.999401 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	44	Target Neighborhood Hits	38	Shared Neighborhood Hits	30
SwissProt Accessions	P28661, Q5ND15	Gene names	Sept4, Pnutl2
Domain Architecture
Description	Septin-4 (Peanut-like protein 2) (Brain protein H5).

SEPT5_HUMAN
NC score	0.996558 (rank : 3)	θ value	1.91371e-159 (rank : 3)
Query Neighborhood Hits	44	Target Neighborhood Hits	44	Shared Neighborhood Hits	22
SwissProt Accessions	Q99719, O15251	Gene names	SEPT5, PNUTL1
Domain Architecture
Description	Septin-5 (Peanut-like protein 1) (Cell division control-related protein 1) (CDCrel-1).

SEPT5_MOUSE
NC score	0.996408 (rank : 4)	θ value	5.56804e-159 (rank : 4)
Query Neighborhood Hits	44	Target Neighborhood Hits	44	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z2Q6, Q3UYG4, Q6PB74	Gene names	Sept5, Pnutl1
Domain Architecture	No domain graphic available
Description	Septin-5 (Peanut-like protein 1) (Cell division control-related protein 1) (CDCrel-1).

SEPT1_MOUSE
NC score	0.993894 (rank : 5)	θ value	1.25199e-126 (rank : 6)
Query Neighborhood Hits	44	Target Neighborhood Hits	58	Shared Neighborhood Hits	23
SwissProt Accessions	P42209	Gene names	Sept1, Diff6, Pnutl3
Domain Architecture
Description	Septin-1 (Differentiation protein 6) (Diff6 protein).

SEPT1_HUMAN
NC score	0.993676 (rank : 6)	θ value	6.85399e-133 (rank : 5)
Query Neighborhood Hits	44	Target Neighborhood Hits	65	Shared Neighborhood Hits	23
SwissProt Accessions	Q8WYJ6, Q8NEZ1, Q96EL4, Q9H285	Gene names	SEPT1, PNUTL3
Domain Architecture
Description	Septin-1 (LARP) (Serologically defined breast cancer antigen NY-BR- 24).

SEPT2_HUMAN
NC score	0.989376 (rank : 7)	θ value	1.06234e-117 (rank : 7)
Query Neighborhood Hits	44	Target Neighborhood Hits	101	Shared Neighborhood Hits	23
SwissProt Accessions	Q15019, Q14132, Q8IUK9, Q96CB0	Gene names	SEPT2, DIFF6, KIAA0158, NEDD5
Domain Architecture
Description	Septin-2 (Protein NEDD5).

SEPT2_MOUSE
NC score	0.989082 (rank : 8)	θ value	1.38745e-117 (rank : 8)
Query Neighborhood Hits	44	Target Neighborhood Hits	105	Shared Neighborhood Hits	23
SwissProt Accessions	P42208, Q3U9Y5	Gene names	Sept2, Nedd-5, Nedd5
Domain Architecture
Description	Septin-2 (Protein NEDD5) (Neural precursor cell expressed developmentally down-regulated protein 5).

SEPT3_HUMAN
NC score	0.980702 (rank : 9)	θ value	2.38869e-85 (rank : 11)
Query Neighborhood Hits	44	Target Neighborhood Hits	56	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UH03, Q6IBZ6, Q8N3P3	Gene names	SEPT3, SEP3
Domain Architecture
Description	Neuronal-specific septin-3.

SEPT3_MOUSE
NC score	0.977279 (rank : 10)	θ value	3.94648e-80 (rank : 14)
Query Neighborhood Hits	44	Target Neighborhood Hits	56	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z1S5	Gene names	Sept3, Sep3
Domain Architecture
Description	Neuronal-specific septin-3.

SEPT7_MOUSE
NC score	0.950237 (rank : 11)	θ value	1.59114e-105 (rank : 10)
Query Neighborhood Hits	44	Target Neighborhood Hits	327	Shared Neighborhood Hits	24
SwissProt Accessions	O55131	Gene names	Sept7, Cdc10
Domain Architecture
Description	Septin-7 (CDC10 protein homolog).

SEP10_MOUSE
NC score	0.949646 (rank : 12)	θ value	1.19101e-68 (rank : 15)
Query Neighborhood Hits	44	Target Neighborhood Hits	145	Shared Neighborhood Hits	23
SwissProt Accessions	Q8C650, Q7TSA5	Gene names	Sept10
Domain Architecture	No domain graphic available
Description	Septin-10.

SEPT9_MOUSE
NC score	0.947608 (rank : 13)	θ value	3.81361e-83 (rank : 13)
Query Neighborhood Hits	44	Target Neighborhood Hits	238	Shared Neighborhood Hits	22
SwissProt Accessions	Q80UG5, Q3URP2, Q80TM7, Q9QYX9	Gene names	Sept9, Kiaa0991, Sint1
Domain Architecture	No domain graphic available
Description	Septin-9 (SL3-3 integration site 1 protein).

SEPT7_HUMAN
NC score	0.947600 (rank : 14)	θ value	1.59114e-105 (rank : 9)
Query Neighborhood Hits	44	Target Neighborhood Hits	385	Shared Neighborhood Hits	24
SwissProt Accessions	Q16181, Q6NX50	Gene names	SEPT7, CDC10
Domain Architecture
Description	Septin-7 (CDC10 protein homolog).

SEP10_HUMAN
NC score	0.945508 (rank : 15)	θ value	8.53533e-67 (rank : 18)
Query Neighborhood Hits	44	Target Neighborhood Hits	161	Shared Neighborhood Hits	22
SwissProt Accessions	Q9P0V9, Q9HAH6	Gene names	SEPT10
Domain Architecture	No domain graphic available
Description	Septin-10.

SEPT6_HUMAN
NC score	0.937785 (rank : 16)	θ value	1.90147e-66 (rank : 19)
Query Neighborhood Hits	44	Target Neighborhood Hits	220	Shared Neighborhood Hits	23
SwissProt Accessions	Q14141, Q5JTK0, Q969W5, Q96A13, Q96GR1, Q96P86, Q96P87	Gene names	SEPT6, KIAA0128, SEP2
Domain Architecture
Description	Septin-6.

SEPT6_MOUSE
NC score	0.934605 (rank : 17)	θ value	1.6097e-65 (rank : 22)
Query Neighborhood Hits	44	Target Neighborhood Hits	244	Shared Neighborhood Hits	23
SwissProt Accessions	Q9R1T4, Q91XH2, Q9CZ94	Gene names	Sept6
Domain Architecture
Description	Septin-6.

SEPT8_MOUSE
NC score	0.931183 (rank : 18)	θ value	7.2256e-66 (rank : 21)
Query Neighborhood Hits	44	Target Neighborhood Hits	251	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CHH9, Q80YC7, Q9ESF7	Gene names	Sept8, Kiaa0202
Domain Architecture
Description	Septin-8.

SEP11_HUMAN
NC score	0.927378 (rank : 19)	θ value	2.93355e-67 (rank : 16)
Query Neighborhood Hits	44	Target Neighborhood Hits	296	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NVA2, Q7L4N1	Gene names	SEPT11
Domain Architecture	No domain graphic available
Description	Septin-11.

SEP11_MOUSE
NC score	0.926656 (rank : 20)	θ value	2.93355e-67 (rank : 17)
Query Neighborhood Hits	44	Target Neighborhood Hits	300	Shared Neighborhood Hits	23
SwissProt Accessions	Q8C1B7, Q6P2K5, Q6P6I0	Gene names	Sept11, D5Ertd606e
Domain Architecture	No domain graphic available
Description	Septin-11.

SEPT8_HUMAN
NC score	0.923812 (rank : 21)	θ value	7.2256e-66 (rank : 20)
Query Neighborhood Hits	44	Target Neighborhood Hits	290	Shared Neighborhood Hits	23
SwissProt Accessions	Q92599, Q8IX36, Q8IX37, Q9BVB3	Gene names	SEPT8, KIAA0202
Domain Architecture
Description	Septin-8.

SEPT9_HUMAN
NC score	0.888910 (rank : 22)	θ value	4.50487e-84 (rank : 12)
Query Neighborhood Hits	44	Target Neighborhood Hits	706	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

IQGA2_HUMAN
NC score	0.022710 (rank : 23)	θ value	0.125558 (rank : 23)
Query Neighborhood Hits	44	Target Neighborhood Hits	200	Shared Neighborhood Hits	4
SwissProt Accessions	Q13576	Gene names	IQGAP2
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP2.

T2FA_HUMAN
NC score	0.021492 (rank : 24)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	44	Target Neighborhood Hits	228	Shared Neighborhood Hits	5
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

AKAP2_HUMAN
NC score	0.012935 (rank : 25)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	44	Target Neighborhood Hits	507	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

MY18A_MOUSE
NC score	0.012793 (rank : 26)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	44	Target Neighborhood Hits	1989	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

GIT2_MOUSE
NC score	0.012298 (rank : 27)	θ value	0.365318 (rank : 24)
Query Neighborhood Hits	44	Target Neighborhood Hits	323	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

MTSS1_HUMAN
NC score	0.010074 (rank : 28)	θ value	1.81305 (rank : 27)
Query Neighborhood Hits	44	Target Neighborhood Hits	504	Shared Neighborhood Hits	5
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

SPF45_HUMAN
NC score	0.008580 (rank : 29)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	44	Target Neighborhood Hits	94	Shared Neighborhood Hits	3
SwissProt Accessions	Q96I25, Q96GY6	Gene names	RBM17, SPF45
Domain Architecture
Description	Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17).

SPF45_MOUSE
NC score	0.008515 (rank : 30)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	44	Target Neighborhood Hits	95	Shared Neighborhood Hits	3
SwissProt Accessions	Q8JZX4, O75939	Gene names	Rbm17, Spf45
Domain Architecture
Description	Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17).

ES8L3_HUMAN
NC score	0.008080 (rank : 31)	θ value	1.81305 (rank : 26)
Query Neighborhood Hits	44	Target Neighborhood Hits	206	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TE67, Q5T8Q6, Q5T8Q7, Q5T8Q8, Q96E47, Q9H719	Gene names	EPS8L3, EPS8R3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

SYTL1_HUMAN
NC score	0.006142 (rank : 32)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	44	Target Neighborhood Hits	227	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IYJ3, Q96BB6, Q96GU6, Q96S89, Q96SI0	Gene names	SYTL1, SLP1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1) (SB146).

TMF1_HUMAN
NC score	0.004635 (rank : 33)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	44	Target Neighborhood Hits	987	Shared Neighborhood Hits	9
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

K1B11_MOUSE
NC score	0.004415 (rank : 34)	θ value	0.813845 (rank : 25)
Query Neighborhood Hits	44	Target Neighborhood Hits	180	Shared Neighborhood Hits	4
SwissProt Accessions	P15946	Gene names	Klk1b11, Klk-11, Klk11
Domain Architecture
Description	Kallikrein 1-related peptidase b11 precursor (EC 3.4.21.35) (Tissue kallikrein-11) (Glandular kallikrein K11) (mGK-11).

MLL2_HUMAN
NC score	0.003853 (rank : 35)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	44	Target Neighborhood Hits	1788	Shared Neighborhood Hits	9
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

P3C2G_HUMAN
NC score	0.003176 (rank : 36)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	44	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	O75747	Gene names	PIK3C2G
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).

CEP57_MOUSE
NC score	0.002733 (rank : 37)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	44	Target Neighborhood Hits	580	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

MDR1_MOUSE
NC score	0.002235 (rank : 38)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	44	Target Neighborhood Hits	105	Shared Neighborhood Hits	3
SwissProt Accessions	P06795	Gene names	Abcb1, Abcb1b, Mdr1, Mdr1b, Pgy1, Pgy1-1
Domain Architecture
Description	Multidrug resistance protein 1 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1) (P-glycoprotein 1) (CD243 antigen).

ATRX_HUMAN
NC score	0.001697 (rank : 39)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	44	Target Neighborhood Hits	842	Shared Neighborhood Hits	5
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

GOGA2_HUMAN
NC score	0.001517 (rank : 40)	θ value	3.0926 (rank : 28)
Query Neighborhood Hits	44	Target Neighborhood Hits	856	Shared Neighborhood Hits	6
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

COR2A_HUMAN
NC score	0.001111 (rank : 41)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	44	Target Neighborhood Hits	214	Shared Neighborhood Hits	2
SwissProt Accessions	Q92828, Q92829, Q9BWS5	Gene names	CORO2A, IR10, WDR2
Domain Architecture
Description	Coronin-2A (WD repeat-containing protein 2) (IR10).

HXA1_MOUSE
NC score	0.000975 (rank : 42)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	44	Target Neighborhood Hits	341	Shared Neighborhood Hits	3
SwissProt Accessions	P09022, P15463	Gene names	Hoxa1, Era-1, Hox-1.6, Hoxa-1
Domain Architecture
Description	Homeobox protein Hox-A1 (Hox-1.6) (Homeotic protein ERA-1-993) (Early retinoic acid 1) (Homeoboxless protein ERA-1-399).

K1KB5_MOUSE
NC score	0.000861 (rank : 43)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	44	Target Neighborhood Hits	177	Shared Neighborhood Hits	3
SwissProt Accessions	P15945, Q52KM1, Q565D7	Gene names	Klk1b5, Klk-5, Klk5
Domain Architecture
Description	Kallikrein 1-related peptidase b5 precursor (EC 3.4.21.35) (Glandular kallikrein K5) (Tissue kallikrein-5) (mGK-5).

ACK1_MOUSE
NC score	-0.002669 (rank : 44)	θ value	6.88961 (rank : 29)
Query Neighborhood Hits	44	Target Neighborhood Hits	1080	Shared Neighborhood Hits	4
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).