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Network neighborhood for query Sequence : SPF45_HUMAN

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SPF45_HUMAN
SwissProt Accessions	Q96I25, Q96GY6	Gene names	RBM17, SPF45
Domain Architecture
Description	Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SPF45_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	94	Target Neighborhood Hits	94	Shared Neighborhood Hits	94
SwissProt Accessions	Q96I25, Q96GY6	Gene names	RBM17, SPF45
Domain Architecture
Description	Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17).

SPF45_MOUSE
θ value	0 (rank : 2)	NC score	0.994041 (rank : 2)
Query Neighborhood Hits	94	Target Neighborhood Hits	95	Shared Neighborhood Hits	82
SwissProt Accessions	Q8JZX4, O75939	Gene names	Rbm17, Spf45
Domain Architecture
Description	Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17).

U2AF2_HUMAN
θ value	1.43324e-05 (rank : 3)	NC score	0.244929 (rank : 3)
Query Neighborhood Hits	94	Target Neighborhood Hits	192	Shared Neighborhood Hits	23
SwissProt Accessions	P26368	Gene names	U2AF2, U2AF65
Domain Architecture
Description	Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (U2 snRNP auxiliary factor large subunit) (hU2AF(65)).

U2AF2_MOUSE
θ value	1.43324e-05 (rank : 4)	NC score	0.244049 (rank : 4)
Query Neighborhood Hits	94	Target Neighborhood Hits	192	Shared Neighborhood Hits	23
SwissProt Accessions	P26369	Gene names	U2af2, U2af65
Domain Architecture
Description	Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (U2 snRNP auxiliary factor large subunit).

UHMK1_HUMAN
θ value	0.000158464 (rank : 5)	NC score	0.086742 (rank : 37)
Query Neighborhood Hits	94	Target Neighborhood Hits	808	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TAS1, Q96C22	Gene names	UHMK1, KIS, KIST
Domain Architecture
Description	Serine/threonine-protein kinase Kist (EC 2.7.11.1) (Kinase interacting with stathmin) (U2AF homology motif kinase 1).

UHMK1_MOUSE
θ value	0.000158464 (rank : 6)	NC score	0.087215 (rank : 36)
Query Neighborhood Hits	94	Target Neighborhood Hits	809	Shared Neighborhood Hits	14
SwissProt Accessions	P97343, Q61775, Q9CYT1	Gene names	Uhmk1, Kis, Kist
Domain Architecture
Description	Serine/threonine-protein kinase Kist (EC 2.7.11.1) (Kinase interacting with stathmin) (U2AF homology motif kinase 1).

HTSF1_MOUSE
θ value	0.00102713 (rank : 7)	NC score	0.196335 (rank : 9)
Query Neighborhood Hits	94	Target Neighborhood Hits	425	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

U2AF1_HUMAN
θ value	0.00134147 (rank : 8)	NC score	0.212708 (rank : 8)
Query Neighborhood Hits	94	Target Neighborhood Hits	40	Shared Neighborhood Hits	11
SwissProt Accessions	Q01081	Gene names	U2AF1, U2AF35
Domain Architecture
Description	Splicing factor U2AF 35 kDa subunit (U2 auxiliary factor 35 kDa subunit) (U2 snRNP auxiliary factor small subunit).

U2AF1_MOUSE
θ value	0.00134147 (rank : 9)	NC score	0.213313 (rank : 7)
Query Neighborhood Hits	94	Target Neighborhood Hits	41	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D883, Q564E4, Q99LX2, Q9CZ98	Gene names	U2af1
Domain Architecture
Description	Splicing factor U2AF 35 kDa subunit (U2 auxiliary factor 35 kDa subunit) (U2 snRNP auxiliary factor small subunit).

K0082_MOUSE
θ value	0.00390308 (rank : 10)	NC score	0.228269 (rank : 5)
Query Neighborhood Hits	94	Target Neighborhood Hits	62	Shared Neighborhood Hits	30
SwissProt Accessions	Q9DBC3, Q3U3G5, Q3U7Y9, Q6A0D5, Q8C7V0	Gene names	Kiaa0082
Domain Architecture	No domain graphic available
Description	Protein KIAA0082.

SON_HUMAN
θ value	0.00390308 (rank : 11)	NC score	0.101458 (rank : 31)
Query Neighborhood Hits	94	Target Neighborhood Hits	1568	Shared Neighborhood Hits	46
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SON_MOUSE
θ value	0.00390308 (rank : 12)	NC score	0.146773 (rank : 25)
Query Neighborhood Hits	94	Target Neighborhood Hits	957	Shared Neighborhood Hits	47
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

HTSF1_HUMAN
θ value	0.00509761 (rank : 13)	NC score	0.188349 (rank : 10)
Query Neighborhood Hits	94	Target Neighborhood Hits	408	Shared Neighborhood Hits	23
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

K0082_HUMAN
θ value	0.00509761 (rank : 14)	NC score	0.228082 (rank : 6)
Query Neighborhood Hits	94	Target Neighborhood Hits	60	Shared Neighborhood Hits	30
SwissProt Accessions	Q8N1G2, Q14670, Q96FJ9	Gene names	KIAA0082
Domain Architecture	No domain graphic available
Description	Protein KIAA0082.

RBM5_HUMAN
θ value	0.163984 (rank : 15)	NC score	0.143010 (rank : 27)
Query Neighborhood Hits	94	Target Neighborhood Hits	216	Shared Neighborhood Hits	40
SwissProt Accessions	P52756, Q93021, Q9BU14, Q9UKY8, Q9UL24	Gene names	RBM5
Domain Architecture
Description	RNA-binding protein 5 (RNA-binding motif protein 5) (Tumor suppressor LUCA15) (Protein G15) (NY-REN-9 antigen).

RBM5_MOUSE
θ value	0.163984 (rank : 16)	NC score	0.142762 (rank : 29)
Query Neighborhood Hits	94	Target Neighborhood Hits	216	Shared Neighborhood Hits	40
SwissProt Accessions	Q91YE7, Q3UZ19, Q99KV9	Gene names	Rbm5, Luca15
Domain Architecture	No domain graphic available
Description	RNA-binding protein 5 (RNA-binding motif protein 5) (Tumor suppressor LUCA15).

PINX1_MOUSE
θ value	0.279714 (rank : 17)	NC score	0.175798 (rank : 11)
Query Neighborhood Hits	94	Target Neighborhood Hits	64	Shared Neighborhood Hits	31
SwissProt Accessions	Q9CZX5, Q91WZ9, Q9D0C2	Gene names	Pinx1, Lpts
Domain Architecture
Description	Pin2-interacting protein X1 (TRF1-interacting protein 1) (Liver- related putative tumor suppressor) (LPTS1) (67-11-3 protein).

ITSN1_MOUSE
θ value	0.365318 (rank : 18)	NC score	0.021342 (rank : 91)
Query Neighborhood Hits	94	Target Neighborhood Hits	1669	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

RBBP6_HUMAN
θ value	0.365318 (rank : 19)	NC score	0.066449 (rank : 43)
Query Neighborhood Hits	94	Target Neighborhood Hits	1135	Shared Neighborhood Hits	25
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RNPC2_HUMAN
θ value	0.365318 (rank : 20)	NC score	0.096232 (rank : 33)
Query Neighborhood Hits	94	Target Neighborhood Hits	250	Shared Neighborhood Hits	26
SwissProt Accessions	Q14498, Q14499	Gene names	RNPC2, HCC1
Domain Architecture
Description	RNA-binding region-containing protein 2 (Hepatocellular carcinoma protein 1) (Splicing factor HCC1).

RNPC2_MOUSE
θ value	0.365318 (rank : 21)	NC score	0.096355 (rank : 32)
Query Neighborhood Hits	94	Target Neighborhood Hits	251	Shared Neighborhood Hits	27
SwissProt Accessions	Q8VH51, Q99KV0	Gene names	Rnpc2, Caper
Domain Architecture
Description	RNA-binding region-containing protein 2 (Coactivator of activating protein 1 and estrogen receptors) (Coactivator of AP-1 and ERs) (Transcription coactivator CAPER).

TXND2_MOUSE
θ value	0.365318 (rank : 22)	NC score	0.049380 (rank : 73)
Query Neighborhood Hits	94	Target Neighborhood Hits	828	Shared Neighborhood Hits	17
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

VPK1_HUMAN
θ value	0.365318 (rank : 23)	NC score	0.172710 (rank : 13)
Query Neighborhood Hits	94	Target Neighborhood Hits	37	Shared Neighborhood Hits	28
SwissProt Accessions	P63119	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_12q14.1 provirus ancestral Pro protein (EC 3.4.23.-) (Protease) (Proteinase) (PR).

VPK9_HUMAN
θ value	0.365318 (rank : 24)	NC score	0.173596 (rank : 12)
Query Neighborhood Hits	94	Target Neighborhood Hits	37	Shared Neighborhood Hits	28
SwissProt Accessions	P63124	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q13.3 provirus ancestral Pro protein (EC 3.4.23.-) (HERV-K104 Pro protein) (Protease) (Proteinase) (PR).

VPK17_HUMAN
θ value	0.47712 (rank : 25)	NC score	0.171198 (rank : 14)
Query Neighborhood Hits	94	Target Neighborhood Hits	38	Shared Neighborhood Hits	27
SwissProt Accessions	P63125	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_11q22.1 provirus ancestral Pro protein (EC 3.4.23.-) (Protease) (Proteinase) (PR).

JHD1B_MOUSE
θ value	0.62314 (rank : 26)	NC score	0.047697 (rank : 74)
Query Neighborhood Hits	94	Target Neighborhood Hits	214	Shared Neighborhood Hits	7
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

PABP5_HUMAN
θ value	0.62314 (rank : 27)	NC score	0.074063 (rank : 38)
Query Neighborhood Hits	94	Target Neighborhood Hits	212	Shared Neighborhood Hits	23
SwissProt Accessions	Q96DU9, Q6P529, Q9UFE5	Gene names	PABPC5, PABP5
Domain Architecture
Description	Polyadenylate-binding protein 5 (Poly(A)-binding protein 5) (PABP 5).

PRGC1_MOUSE
θ value	0.62314 (rank : 28)	NC score	0.068502 (rank : 40)
Query Neighborhood Hits	94	Target Neighborhood Hits	238	Shared Neighborhood Hits	16
SwissProt Accessions	O70343	Gene names	Ppargc1a, Pgc1, Pgc1a, Ppargc1
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPAR gamma coactivator 1-alpha) (PPARGC-1-alpha) (PGC-1-alpha).

VPK11_HUMAN
θ value	0.62314 (rank : 29)	NC score	0.167477 (rank : 16)
Query Neighborhood Hits	94	Target Neighborhood Hits	35	Shared Neighborhood Hits	27
SwissProt Accessions	P63129, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Pro protein (EC 3.4.23.-) (HERV- K101 envelope protein) (Protease) (Proteinase) (PR).

VPK7_HUMAN
θ value	0.62314 (rank : 30)	NC score	0.170452 (rank : 15)
Query Neighborhood Hits	94	Target Neighborhood Hits	38	Shared Neighborhood Hits	27
SwissProt Accessions	P63123	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q23.3 provirus ancestral Pro protein (EC 3.4.23.-) (HERV-K18 Pro protein) (HERV-K110 Pro protein) (HERV-K(C1a) Pro protein) (Protease) (Proteinase) (PR).

PINX1_HUMAN
θ value	0.813845 (rank : 31)	NC score	0.154729 (rank : 24)
Query Neighborhood Hits	94	Target Neighborhood Hits	65	Shared Neighborhood Hits	30
SwissProt Accessions	Q96BK5, Q7Z7J8, Q96QD7, Q9HBU7, Q9NWW2	Gene names	PINX1, LPTS
Domain Architecture
Description	Pin2-interacting protein X1 (TRF1-interacting protein 1) (Liver- related putative tumor suppressor) (67-11-3 protein).

TFP11_HUMAN
θ value	0.813845 (rank : 32)	NC score	0.145504 (rank : 26)
Query Neighborhood Hits	94	Target Neighborhood Hits	73	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UBB9, O95908, Q5H8V8, Q9UGV7, Q9Y2Q8	Gene names	TFIP11
Domain Architecture
Description	Tuftelin-interacting protein 11.

VPK3_HUMAN
θ value	0.813845 (rank : 33)	NC score	0.166610 (rank : 18)
Query Neighborhood Hits	94	Target Neighborhood Hits	35	Shared Neighborhood Hits	27
SwissProt Accessions	P63120	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19q12 provirus ancestral Pro protein (EC 3.4.23.-) (HERV-K(C19) Pro protein) (Protease) (Proteinase) (PR).

VPK4_HUMAN
θ value	0.813845 (rank : 34)	NC score	0.161930 (rank : 23)
Query Neighborhood Hits	94	Target Neighborhood Hits	33	Shared Neighborhood Hits	27
SwissProt Accessions	P63127, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Pro protein (EC 3.4.23.-) (HERV-K109 Pro protein) (HERV-K(C6) Pro protein) (Protease) (Proteinase) (PR).

VPK6_HUMAN
θ value	0.813845 (rank : 35)	NC score	0.162018 (rank : 22)
Query Neighborhood Hits	94	Target Neighborhood Hits	35	Shared Neighborhood Hits	27
SwissProt Accessions	P63122	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Pro protein (EC 3.4.23.-) (HERV-K115 Pro protein) (Protease) (Proteinase) (PR).

JHD1B_HUMAN
θ value	1.06291 (rank : 36)	NC score	0.047195 (rank : 76)
Query Neighborhood Hits	94	Target Neighborhood Hits	178	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NHM5, Q8NCI2, Q96HC7, Q96SL0, Q96T03, Q9NS96, Q9UF75	Gene names	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (Protein JEMMA) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (CXXC-type zinc finger protein 2) (Protein-containing CXXC domain 2).

TFP11_MOUSE
θ value	1.06291 (rank : 37)	NC score	0.142993 (rank : 28)
Query Neighborhood Hits	94	Target Neighborhood Hits	95	Shared Neighborhood Hits	30
SwissProt Accessions	Q9ERA6, Q8VD06	Gene names	Tfip11, Tip39
Domain Architecture
Description	Tuftelin-interacting protein 11 (Tuftelin-interacting protein 39).

VPK10_HUMAN
θ value	1.06291 (rank : 38)	NC score	0.166568 (rank : 19)
Query Neighborhood Hits	94	Target Neighborhood Hits	38	Shared Neighborhood Hits	28
SwissProt Accessions	P10265, Q9UKH6	Gene names
Domain Architecture
Description	HERV-K_5q33.3 provirus ancestral Pro protein (EC 3.4.23.-) (HERV-K10 Pro protein) (HERV-K107 Pro protein) (Protease) (Proteinase) (PR).

VPK12_HUMAN
θ value	1.06291 (rank : 39)	NC score	0.166528 (rank : 20)
Query Neighborhood Hits	94	Target Neighborhood Hits	37	Shared Neighborhood Hits	28
SwissProt Accessions	P63131, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Pro protein (EC 3.4.23.-) (HERV-K102 Pro protein) (HERV-K(III) Pro protein) (Protease) (Proteinase) (PR).

VPK5_HUMAN
θ value	1.06291 (rank : 40)	NC score	0.166686 (rank : 17)
Query Neighborhood Hits	94	Target Neighborhood Hits	38	Shared Neighborhood Hits	28
SwissProt Accessions	P63121	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Pro protein (EC 3.4.23.-) (HERV- K113 envelope protein) (Protease) (Proteinase) (PR).

WWC3_HUMAN
θ value	1.06291 (rank : 41)	NC score	0.051395 (rank : 71)
Query Neighborhood Hits	94	Target Neighborhood Hits	193	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ULE0, Q659C1, Q9BTQ1	Gene names	WWC3, KIAA1280
Domain Architecture	No domain graphic available
Description	WWC family member 3.

DNJC7_HUMAN
θ value	1.38821 (rank : 42)	NC score	0.038155 (rank : 80)
Query Neighborhood Hits	94	Target Neighborhood Hits	212	Shared Neighborhood Hits	7
SwissProt Accessions	Q99615	Gene names	DNAJC7, TPR2, TTC2
Domain Architecture
Description	DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2).

DNJC7_MOUSE
θ value	1.38821 (rank : 43)	NC score	0.038476 (rank : 79)
Query Neighborhood Hits	94	Target Neighborhood Hits	211	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QYI3, Q3TKR1, Q8BPG3, Q8CIL2, Q9CT29, Q9D026	Gene names	Dnajc7, Ttc2
Domain Architecture
Description	DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2) (MDj11).

MAMC1_MOUSE
θ value	1.38821 (rank : 44)	NC score	0.024257 (rank : 89)
Query Neighborhood Hits	94	Target Neighborhood Hits	357	Shared Neighborhood Hits	4
SwissProt Accessions	P60755	Gene names	Mamdc1, Mdga2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

MYH9_HUMAN
θ value	1.38821 (rank : 45)	NC score	0.011871 (rank : 102)
Query Neighborhood Hits	94	Target Neighborhood Hits	1762	Shared Neighborhood Hits	15
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

RB15B_HUMAN
θ value	1.38821 (rank : 46)	NC score	0.065259 (rank : 44)
Query Neighborhood Hits	94	Target Neighborhood Hits	251	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NDT2, Q6QE19, Q9BV96	Gene names	RBM15B
Domain Architecture	No domain graphic available
Description	Putative RNA-binding protein 15B (RNA-binding motif protein 15B).

RB15B_MOUSE
θ value	1.38821 (rank : 47)	NC score	0.067696 (rank : 41)
Query Neighborhood Hits	94	Target Neighborhood Hits	284	Shared Neighborhood Hits	18
SwissProt Accessions	Q6PHZ5, Q8C6G2	Gene names	Rbm15b
Domain Architecture	No domain graphic available
Description	Putative RNA-binding protein 15B (RNA-binding motif protein 15B).

VPK2_HUMAN
θ value	1.38821 (rank : 48)	NC score	0.164098 (rank : 21)
Query Neighborhood Hits	94	Target Neighborhood Hits	39	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y6I0, Q9UKH5	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Pro protein (EC 3.4.23.-) (HERV- K(HML-2.HOM) Pro protein) (HERV-K108 Pro protein) (HERV-K(C7) Pro protein) (Protease) (Proteinase) (PR).

PABP4_HUMAN
θ value	1.81305 (rank : 49)	NC score	0.072111 (rank : 39)
Query Neighborhood Hits	94	Target Neighborhood Hits	268	Shared Neighborhood Hits	29
SwissProt Accessions	Q13310, Q6P0N3	Gene names	PABPC4, APP1, PABP4
Domain Architecture
Description	Polyadenylate-binding protein 4 (Poly(A)-binding protein 4) (PABP 4) (Inducible poly(A)-binding protein) (iPABP) (Activated-platelet protein 1) (APP-1).

CASP8_MOUSE
θ value	2.36792 (rank : 50)	NC score	0.027723 (rank : 85)
Query Neighborhood Hits	94	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	O89110, O35669	Gene names	Casp8
Domain Architecture
Description	Caspase-8 precursor (EC 3.4.22.-) (CASP-8) [Contains: Caspase-8 subunit p18; Caspase-8 subunit p10].

MYCB2_HUMAN
θ value	2.36792 (rank : 51)	NC score	0.027520 (rank : 86)
Query Neighborhood Hits	94	Target Neighborhood Hits	390	Shared Neighborhood Hits	10
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

DNJC8_HUMAN
θ value	3.0926 (rank : 52)	NC score	0.047272 (rank : 75)
Query Neighborhood Hits	94	Target Neighborhood Hits	380	Shared Neighborhood Hits	12
SwissProt Accessions	O75937, Q6IBA4, Q8N4Z5, Q9P051, Q9P067	Gene names	DNAJC8, SPF31
Domain Architecture
Description	DnaJ homolog subfamily C member 8 (Splicing protein spf31).

DNJC8_MOUSE
θ value	3.0926 (rank : 53)	NC score	0.047020 (rank : 77)
Query Neighborhood Hits	94	Target Neighborhood Hits	392	Shared Neighborhood Hits	11
SwissProt Accessions	Q6NZB0, Q6PG72, Q8C2M6	Gene names	Dnajc8
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 8.

GDF2_HUMAN
θ value	3.0926 (rank : 54)	NC score	0.018302 (rank : 95)
Query Neighborhood Hits	94	Target Neighborhood Hits	77	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UK05, Q9Y571	Gene names	GDF2, BMP9
Domain Architecture
Description	Growth/differentiation factor 2 precursor (GDF-2) (Bone morphogenetic protein 9) (BMP-9).

GSCR2_HUMAN
θ value	3.0926 (rank : 55)	NC score	0.053419 (rank : 64)
Query Neighborhood Hits	94	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NZM5, Q9BTC6, Q9HAX6, Q9NPP1, Q9NPR4, Q9UFI2	Gene names	GLTSCR2
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 2 protein (p60).

LPIN1_HUMAN
θ value	3.0926 (rank : 56)	NC score	0.026174 (rank : 87)
Query Neighborhood Hits	94	Target Neighborhood Hits	36	Shared Neighborhood Hits	6
SwissProt Accessions	Q14693	Gene names	LPIN1, KIAA0188
Domain Architecture
Description	Lipin-1.

MAMC1_HUMAN
θ value	3.0926 (rank : 57)	NC score	0.020987 (rank : 92)
Query Neighborhood Hits	94	Target Neighborhood Hits	357	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z553	Gene names	MAMDC1, MDGA2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

MYH9_MOUSE
θ value	3.0926 (rank : 58)	NC score	0.011699 (rank : 103)
Query Neighborhood Hits	94	Target Neighborhood Hits	1829	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

RBM10_HUMAN
θ value	3.0926 (rank : 59)	NC score	0.112034 (rank : 30)
Query Neighborhood Hits	94	Target Neighborhood Hits	204	Shared Neighborhood Hits	36
SwissProt Accessions	P98175, Q14136	Gene names	RBM10, DXS8237E, KIAA0122
Domain Architecture
Description	RNA-binding protein 10 (RNA-binding motif protein 10).

RBM12_HUMAN
θ value	3.0926 (rank : 60)	NC score	0.056705 (rank : 55)
Query Neighborhood Hits	94	Target Neighborhood Hits	298	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NTZ6, O94865, Q8N3B1, Q9H196	Gene names	RBM12, KIAA0765
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

RBM12_MOUSE
θ value	3.0926 (rank : 61)	NC score	0.057239 (rank : 54)
Query Neighborhood Hits	94	Target Neighborhood Hits	313	Shared Neighborhood Hits	18
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

AGGF1_MOUSE
θ value	4.03905 (rank : 62)	NC score	0.094655 (rank : 34)
Query Neighborhood Hits	94	Target Neighborhood Hits	155	Shared Neighborhood Hits	31
SwissProt Accessions	Q7TN31, Q8R2S6, Q9CQR9, Q9CU87, Q9D768	Gene names	Aggf1, Vg5q
Domain Architecture
Description	Angiogenic factor with G patch and FHA domains 1 (Angiogenic factor VG5Q) (mVG5Q).

CTNA3_MOUSE
θ value	4.03905 (rank : 63)	NC score	0.014032 (rank : 98)
Query Neighborhood Hits	94	Target Neighborhood Hits	55	Shared Neighborhood Hits	2
SwissProt Accessions	Q65CL1, Q3UQ61, Q8C0N3	Gene names	Ctnna3, Catna3
Domain Architecture	No domain graphic available
Description	Catenin alpha-3 (Alpha T-catenin) (Cadherin-associated protein).

ENAM_HUMAN
θ value	4.03905 (rank : 64)	NC score	0.034962 (rank : 81)
Query Neighborhood Hits	94	Target Neighborhood Hits	227	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NRM1, Q9H3D1	Gene names	ENAM
Domain Architecture
Description	Enamelin precursor.

MAGI2_HUMAN
θ value	4.03905 (rank : 65)	NC score	0.019933 (rank : 94)
Query Neighborhood Hits	94	Target Neighborhood Hits	373	Shared Neighborhood Hits	7
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

MYOC_HUMAN
θ value	4.03905 (rank : 66)	NC score	0.017854 (rank : 96)
Query Neighborhood Hits	94	Target Neighborhood Hits	489	Shared Neighborhood Hits	6
SwissProt Accessions	Q99972, O00620, Q7Z6Q9	Gene names	MYOC, GLC1A, TIGR
Domain Architecture
Description	Myocilin precursor (Trabecular meshwork-induced glucocorticoid response protein).

AGGF1_HUMAN
θ value	5.27518 (rank : 67)	NC score	0.090672 (rank : 35)
Query Neighborhood Hits	94	Target Neighborhood Hits	271	Shared Neighborhood Hits	32
SwissProt Accessions	Q8N302, O00581, Q53YS3, Q9BU84, Q9NW66	Gene names	AGGF1, VG5Q
Domain Architecture
Description	Angiogenic factor with G patch and FHA domains 1 (Angiogenic factor VG5Q) (Vasculogenesis gene on 5q protein) (hVG5Q).

MAGI2_MOUSE
θ value	5.27518 (rank : 68)	NC score	0.015450 (rank : 97)
Query Neighborhood Hits	94	Target Neighborhood Hits	370	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

TRDN_HUMAN
θ value	5.27518 (rank : 69)	NC score	0.025732 (rank : 88)
Query Neighborhood Hits	94	Target Neighborhood Hits	542	Shared Neighborhood Hits	12
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

ZN318_HUMAN
θ value	5.27518 (rank : 70)	NC score	0.032517 (rank : 83)
Query Neighborhood Hits	94	Target Neighborhood Hits	497	Shared Neighborhood Hits	14
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

ANK2_HUMAN
θ value	6.88961 (rank : 71)	NC score	0.009255 (rank : 105)
Query Neighborhood Hits	94	Target Neighborhood Hits	1615	Shared Neighborhood Hits	25
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

CCNK_MOUSE
θ value	6.88961 (rank : 72)	NC score	0.033608 (rank : 82)
Query Neighborhood Hits	94	Target Neighborhood Hits	350	Shared Neighborhood Hits	9
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

CSTFT_HUMAN
θ value	6.88961 (rank : 73)	NC score	0.056502 (rank : 56)
Query Neighborhood Hits	94	Target Neighborhood Hits	292	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H0L4, O75174, Q53HK6, Q7LGE8, Q8N6T1	Gene names	CSTF2T, KIAA0689
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 64 kDa subunit, tau variant (CSTF 64 kDa subunit, tau variant) (CF-1 64 kDa subunit, tau variant) (TauCstF-64).

CSTFT_MOUSE
θ value	6.88961 (rank : 74)	NC score	0.059861 (rank : 49)
Query Neighborhood Hits	94	Target Neighborhood Hits	356	Shared Neighborhood Hits	20
SwissProt Accessions	Q8C7E9, Q6A016, Q8BHH7, Q8C3W7, Q8R2Y1, Q9EPU3	Gene names	Cstf2t, Kiaa0689
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 64 kDa subunit, tau variant (CSTF 64 kDa subunit, tau variant) (CF-1 64 kDa subunit, tau variant) (TauCstF-64).

ELOA1_HUMAN
θ value	6.88961 (rank : 75)	NC score	0.021475 (rank : 90)
Query Neighborhood Hits	94	Target Neighborhood Hits	388	Shared Neighborhood Hits	13
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

GPTC3_MOUSE
θ value	6.88961 (rank : 76)	NC score	0.052779 (rank : 69)
Query Neighborhood Hits	94	Target Neighborhood Hits	52	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BIY1	Gene names	Gpatc3
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 3.

RIMS2_HUMAN
θ value	6.88961 (rank : 77)	NC score	0.012211 (rank : 101)
Query Neighborhood Hits	94	Target Neighborhood Hits	342	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

SF04_HUMAN
θ value	6.88961 (rank : 78)	NC score	0.066586 (rank : 42)
Query Neighborhood Hits	94	Target Neighborhood Hits	83	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IWZ8, O60378, Q6P3X9, Q8TCQ4, Q8WWT4, Q8WWT5, Q9NTG3	Gene names	SF4
Domain Architecture	No domain graphic available
Description	Splicing factor 4 (RNA-binding protein RBP).

SFR14_MOUSE
θ value	6.88961 (rank : 79)	NC score	0.059580 (rank : 50)
Query Neighborhood Hits	94	Target Neighborhood Hits	238	Shared Neighborhood Hits	28
SwissProt Accessions	Q8CH09, Q6PG19, Q80UY8, Q8BY32, Q8CFM0	Gene names	Sfrs14
Domain Architecture	No domain graphic available
Description	Putative splicing factor, arginine/serine-rich 14 (Arginine/serine- rich-splicing factor 14).

SRRM1_HUMAN
θ value	6.88961 (rank : 80)	NC score	0.031235 (rank : 84)
Query Neighborhood Hits	94	Target Neighborhood Hits	690	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

TOR3A_HUMAN
θ value	6.88961 (rank : 81)	NC score	0.020442 (rank : 93)
Query Neighborhood Hits	94	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H497, Q5M7Y7, Q8WVA7, Q8WWM2, Q9H495, Q9H6E7	Gene names	TOR3A, ADIR
Domain Architecture	No domain graphic available
Description	Torsin-3A precursor (Torsin family 3 member A) (ATP-dependent interferon-responsive protein).

BRD8_HUMAN
θ value	8.99809 (rank : 82)	NC score	0.013038 (rank : 99)
Query Neighborhood Hits	94	Target Neighborhood Hits	292	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

CSTF2_HUMAN
θ value	8.99809 (rank : 83)	NC score	0.058567 (rank : 52)
Query Neighborhood Hits	94	Target Neighborhood Hits	296	Shared Neighborhood Hits	23
SwissProt Accessions	P33240, Q5H951, Q6LA74, Q8N502	Gene names	CSTF2
Domain Architecture
Description	Cleavage stimulation factor 64 kDa subunit (CSTF 64 kDa subunit) (CF-1 64 kDa subunit) (CstF-64).

CSTF2_MOUSE
θ value	8.99809 (rank : 84)	NC score	0.059888 (rank : 48)
Query Neighborhood Hits	94	Target Neighborhood Hits	255	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BIQ5, Q8K1Y6, Q9ERC2	Gene names	Cstf2
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 64 kDa subunit (CSTF 64 kDa subunit) (CF-1 64 kDa subunit) (CstF-64).

MINT_MOUSE
θ value	8.99809 (rank : 85)	NC score	0.042875 (rank : 78)
Query Neighborhood Hits	94	Target Neighborhood Hits	1514	Shared Neighborhood Hits	38
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

PABP1_MOUSE
θ value	8.99809 (rank : 86)	NC score	0.060842 (rank : 46)
Query Neighborhood Hits	94	Target Neighborhood Hits	278	Shared Neighborhood Hits	30
SwissProt Accessions	P29341	Gene names	Pabpc1, Pabp1
Domain Architecture
Description	Polyadenylate-binding protein 1 (Poly(A)-binding protein 1) (PABP 1).

PCD15_MOUSE
θ value	8.99809 (rank : 87)	NC score	0.012213 (rank : 100)
Query Neighborhood Hits	94	Target Neighborhood Hits	262	Shared Neighborhood Hits	6
SwissProt Accessions	Q99PJ1	Gene names	Pcdh15
Domain Architecture
Description	Protocadherin-15 precursor.

PRDM9_HUMAN
θ value	8.99809 (rank : 88)	NC score	-0.002113 (rank : 109)
Query Neighborhood Hits	94	Target Neighborhood Hits	750	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NQV7	Gene names	PRDM9, PFM6
Domain Architecture
Description	PR domain zinc finger protein 9 (PR domain-containing protein 9).

SEPT4_HUMAN
θ value	8.99809 (rank : 89)	NC score	0.008580 (rank : 107)
Query Neighborhood Hits	94	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	O43236, Q9UM58	Gene names	SEPT4, PNUTL2
Domain Architecture
Description	Septin-4 (Peanut-like protein 2) (Brain protein H5) (Cell division control-related protein 2) (hCDCREL-2) (Bradeion beta) (CE5B3 beta) (Cerebral protein 7).

TIA1_HUMAN
θ value	8.99809 (rank : 90)	NC score	0.053116 (rank : 68)
Query Neighborhood Hits	94	Target Neighborhood Hits	236	Shared Neighborhood Hits	25
SwissProt Accessions	P31483	Gene names	TIA1
Domain Architecture	No domain graphic available
Description	Nucleolysin TIA-1 isoform p40 (RNA-binding protein TIA-1) (p40-TIA-1) [Contains: Nucleolysin TIA-1 isoform p15 (p15-TIA-1)].

TIA1_MOUSE
θ value	8.99809 (rank : 91)	NC score	0.052571 (rank : 70)
Query Neighborhood Hits	94	Target Neighborhood Hits	241	Shared Neighborhood Hits	26
SwissProt Accessions	P52912	Gene names	Tia1, Tia
Domain Architecture
Description	Nucleolysin TIA-1 (RNA-binding protein TIA-1).

TUFT1_MOUSE
θ value	8.99809 (rank : 92)	NC score	0.010329 (rank : 104)
Query Neighborhood Hits	94	Target Neighborhood Hits	732	Shared Neighborhood Hits	9
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

ZFP64_MOUSE
θ value	8.99809 (rank : 93)	NC score	-0.001684 (rank : 108)
Query Neighborhood Hits	94	Target Neighborhood Hits	733	Shared Neighborhood Hits	3
SwissProt Accessions	Q99KE8, P97365, Q9CWR3	Gene names	Zfp64
Domain Architecture	No domain graphic available
Description	Zinc finger protein 64 (Zfp-64).

ZYX_MOUSE
θ value	8.99809 (rank : 94)	NC score	0.008774 (rank : 106)
Query Neighborhood Hits	94	Target Neighborhood Hits	347	Shared Neighborhood Hits	4
SwissProt Accessions	Q62523, P70461	Gene names	Zyx
Domain Architecture
Description	Zyxin.

GPTC2_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.058066 (rank : 53)
Query Neighborhood Hits	94	Target Neighborhood Hits	50	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NW75, Q86YE7	Gene names	GPATC2
Domain Architecture
Description	G patch domain-containing protein 2.

GPTC2_MOUSE
θ value	θ > 10 (rank : 96)	NC score	0.053286 (rank : 66)
Query Neighborhood Hits	94	Target Neighborhood Hits	61	Shared Neighborhood Hits	28
SwissProt Accessions	Q7TQC7, Q8BNJ9, Q8BPM1, Q8CDH9	Gene names	Gpatc2
Domain Architecture
Description	G patch domain-containing protein 2.

MAN1_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.054906 (rank : 59)
Query Neighborhood Hits	94	Target Neighborhood Hits	37	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y2U8, Q9NT47, Q9NYA5	Gene names	LEMD3, MAN1
Domain Architecture
Description	Inner nuclear membrane protein Man1 (LEM domain-containing protein 3).

NKRF_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.055050 (rank : 58)
Query Neighborhood Hits	94	Target Neighborhood Hits	57	Shared Neighborhood Hits	29
SwissProt Accessions	O15226, Q9UJ91	Gene names	NKRF, ITBA4, NRF
Domain Architecture
Description	NF-kappa-B-repressing factor (NFKB-repressing factor) (Transcription factor NRF) (ITBA4 protein).

NKRF_MOUSE
θ value	θ > 10 (rank : 99)	NC score	0.054450 (rank : 61)
Query Neighborhood Hits	94	Target Neighborhood Hits	67	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BY02, Q8BJU5, Q9CRL2	Gene names	Nkrf, Nrf
Domain Architecture
Description	NF-kappa-B-repressing factor (NFKB-repressing factor) (Transcription factor NRF).

PABP1_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.053237 (rank : 67)
Query Neighborhood Hits	94	Target Neighborhood Hits	269	Shared Neighborhood Hits	23
SwissProt Accessions	P11940, Q15097, Q93004	Gene names	PABPC1, PAB1, PABP1, PABPC2
Domain Architecture
Description	Polyadenylate-binding protein 1 (Poly(A)-binding protein 1) (PABP 1).

PABP3_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.053396 (rank : 65)
Query Neighborhood Hits	94	Target Neighborhood Hits	259	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H361, Q8NHV0, Q9H086	Gene names	PABPC3, PABP3, PABPL3
Domain Architecture
Description	Polyadenylate-binding protein 3 (Poly(A)-binding protein 3) (PABP 3) (Testis-specific poly(A)-binding protein).

RBM23_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.055298 (rank : 57)
Query Neighborhood Hits	94	Target Neighborhood Hits	235	Shared Neighborhood Hits	20
SwissProt Accessions	Q86U06, Q8ND16, Q8TB88, Q8WY40, Q9BUJ1, Q9NVV7	Gene names	RBM23, RNPC4
Domain Architecture
Description	Probable RNA-binding protein 23 (RNA-binding motif protein 23) (RNA- binding region-containing protein 4) (Splicing factor SF2).

RBMX2_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.054367 (rank : 62)
Query Neighborhood Hits	94	Target Neighborhood Hits	351	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y388, Q5JY82, Q9Y3I8	Gene names	RBMX2
Domain Architecture
Description	RNA-binding motif protein, X-linked 2.

RBMX2_MOUSE
θ value	θ > 10 (rank : 104)	NC score	0.050890 (rank : 72)
Query Neighborhood Hits	94	Target Neighborhood Hits	287	Shared Neighborhood Hits	25
SwissProt Accessions	Q8R0F5, Q3TI42	Gene names	Rbmx2
Domain Architecture
Description	RNA-binding motif protein, X-linked 2.

SF04_MOUSE
θ value	θ > 10 (rank : 105)	NC score	0.054161 (rank : 63)
Query Neighborhood Hits	94	Target Neighborhood Hits	95	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CH02, Q8R094	Gene names	Sf4
Domain Architecture	No domain graphic available
Description	Splicing factor 4.

U2AFL_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.060592 (rank : 47)
Query Neighborhood Hits	94	Target Neighborhood Hits	503	Shared Neighborhood Hits	21
SwissProt Accessions	Q15695, Q13570	Gene names	ZRSR1, U2AF1-RS1, U2AF1L1, U2AF1RS1, U2AFBPL
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 1 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1).

U2AFL_MOUSE
θ value	θ > 10 (rank : 107)	NC score	0.061533 (rank : 45)
Query Neighborhood Hits	94	Target Neighborhood Hits	389	Shared Neighborhood Hits	22
SwissProt Accessions	Q64707	Gene names	Zrsr1, Sp2, Sp2-7, U2af1-rs1, U2af1l1
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 1 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1) (SP2).

U2AFM_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.059167 (rank : 51)
Query Neighborhood Hits	94	Target Neighborhood Hits	577	Shared Neighborhood Hits	24
SwissProt Accessions	Q15696	Gene names	ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (NY-REN-20 antigen).

U2AFM_MOUSE
θ value	θ > 10 (rank : 109)	NC score	0.054742 (rank : 60)
Query Neighborhood Hits	94	Target Neighborhood Hits	543	Shared Neighborhood Hits	21
SwissProt Accessions	Q62377	Gene names	Zrsr2, U2af1-rs2, U2af1l2, U2af1rs2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2).

Hits sorted by NC score

SPF45_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	94	Target Neighborhood Hits	94	Shared Neighborhood Hits	94
SwissProt Accessions	Q96I25, Q96GY6	Gene names	RBM17, SPF45
Domain Architecture
Description	Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17).

SPF45_MOUSE
NC score	0.994041 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	94	Target Neighborhood Hits	95	Shared Neighborhood Hits	82
SwissProt Accessions	Q8JZX4, O75939	Gene names	Rbm17, Spf45
Domain Architecture
Description	Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17).

U2AF2_HUMAN
NC score	0.244929 (rank : 3)	θ value	1.43324e-05 (rank : 3)
Query Neighborhood Hits	94	Target Neighborhood Hits	192	Shared Neighborhood Hits	23
SwissProt Accessions	P26368	Gene names	U2AF2, U2AF65
Domain Architecture
Description	Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (U2 snRNP auxiliary factor large subunit) (hU2AF(65)).

U2AF2_MOUSE
NC score	0.244049 (rank : 4)	θ value	1.43324e-05 (rank : 4)
Query Neighborhood Hits	94	Target Neighborhood Hits	192	Shared Neighborhood Hits	23
SwissProt Accessions	P26369	Gene names	U2af2, U2af65
Domain Architecture
Description	Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (U2 snRNP auxiliary factor large subunit).

K0082_MOUSE
NC score	0.228269 (rank : 5)	θ value	0.00390308 (rank : 10)
Query Neighborhood Hits	94	Target Neighborhood Hits	62	Shared Neighborhood Hits	30
SwissProt Accessions	Q9DBC3, Q3U3G5, Q3U7Y9, Q6A0D5, Q8C7V0	Gene names	Kiaa0082
Domain Architecture	No domain graphic available
Description	Protein KIAA0082.

K0082_HUMAN
NC score	0.228082 (rank : 6)	θ value	0.00509761 (rank : 14)
Query Neighborhood Hits	94	Target Neighborhood Hits	60	Shared Neighborhood Hits	30
SwissProt Accessions	Q8N1G2, Q14670, Q96FJ9	Gene names	KIAA0082
Domain Architecture	No domain graphic available
Description	Protein KIAA0082.

U2AF1_MOUSE
NC score	0.213313 (rank : 7)	θ value	0.00134147 (rank : 9)
Query Neighborhood Hits	94	Target Neighborhood Hits	41	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D883, Q564E4, Q99LX2, Q9CZ98	Gene names	U2af1
Domain Architecture
Description	Splicing factor U2AF 35 kDa subunit (U2 auxiliary factor 35 kDa subunit) (U2 snRNP auxiliary factor small subunit).

U2AF1_HUMAN
NC score	0.212708 (rank : 8)	θ value	0.00134147 (rank : 8)
Query Neighborhood Hits	94	Target Neighborhood Hits	40	Shared Neighborhood Hits	11
SwissProt Accessions	Q01081	Gene names	U2AF1, U2AF35
Domain Architecture
Description	Splicing factor U2AF 35 kDa subunit (U2 auxiliary factor 35 kDa subunit) (U2 snRNP auxiliary factor small subunit).

HTSF1_MOUSE
NC score	0.196335 (rank : 9)	θ value	0.00102713 (rank : 7)
Query Neighborhood Hits	94	Target Neighborhood Hits	425	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

HTSF1_HUMAN
NC score	0.188349 (rank : 10)	θ value	0.00509761 (rank : 13)
Query Neighborhood Hits	94	Target Neighborhood Hits	408	Shared Neighborhood Hits	23
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

PINX1_MOUSE
NC score	0.175798 (rank : 11)	θ value	0.279714 (rank : 17)
Query Neighborhood Hits	94	Target Neighborhood Hits	64	Shared Neighborhood Hits	31
SwissProt Accessions	Q9CZX5, Q91WZ9, Q9D0C2	Gene names	Pinx1, Lpts
Domain Architecture
Description	Pin2-interacting protein X1 (TRF1-interacting protein 1) (Liver- related putative tumor suppressor) (LPTS1) (67-11-3 protein).

VPK9_HUMAN
NC score	0.173596 (rank : 12)	θ value	0.365318 (rank : 24)
Query Neighborhood Hits	94	Target Neighborhood Hits	37	Shared Neighborhood Hits	28
SwissProt Accessions	P63124	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q13.3 provirus ancestral Pro protein (EC 3.4.23.-) (HERV-K104 Pro protein) (Protease) (Proteinase) (PR).

VPK1_HUMAN
NC score	0.172710 (rank : 13)	θ value	0.365318 (rank : 23)
Query Neighborhood Hits	94	Target Neighborhood Hits	37	Shared Neighborhood Hits	28
SwissProt Accessions	P63119	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_12q14.1 provirus ancestral Pro protein (EC 3.4.23.-) (Protease) (Proteinase) (PR).

VPK17_HUMAN
NC score	0.171198 (rank : 14)	θ value	0.47712 (rank : 25)
Query Neighborhood Hits	94	Target Neighborhood Hits	38	Shared Neighborhood Hits	27
SwissProt Accessions	P63125	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_11q22.1 provirus ancestral Pro protein (EC 3.4.23.-) (Protease) (Proteinase) (PR).

VPK7_HUMAN
NC score	0.170452 (rank : 15)	θ value	0.62314 (rank : 30)
Query Neighborhood Hits	94	Target Neighborhood Hits	38	Shared Neighborhood Hits	27
SwissProt Accessions	P63123	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q23.3 provirus ancestral Pro protein (EC 3.4.23.-) (HERV-K18 Pro protein) (HERV-K110 Pro protein) (HERV-K(C1a) Pro protein) (Protease) (Proteinase) (PR).

VPK11_HUMAN
NC score	0.167477 (rank : 16)	θ value	0.62314 (rank : 29)
Query Neighborhood Hits	94	Target Neighborhood Hits	35	Shared Neighborhood Hits	27
SwissProt Accessions	P63129, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Pro protein (EC 3.4.23.-) (HERV- K101 envelope protein) (Protease) (Proteinase) (PR).

VPK5_HUMAN
NC score	0.166686 (rank : 17)	θ value	1.06291 (rank : 40)
Query Neighborhood Hits	94	Target Neighborhood Hits	38	Shared Neighborhood Hits	28
SwissProt Accessions	P63121	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Pro protein (EC 3.4.23.-) (HERV- K113 envelope protein) (Protease) (Proteinase) (PR).

VPK3_HUMAN
NC score	0.166610 (rank : 18)	θ value	0.813845 (rank : 33)
Query Neighborhood Hits	94	Target Neighborhood Hits	35	Shared Neighborhood Hits	27
SwissProt Accessions	P63120	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19q12 provirus ancestral Pro protein (EC 3.4.23.-) (HERV-K(C19) Pro protein) (Protease) (Proteinase) (PR).

VPK10_HUMAN
NC score	0.166568 (rank : 19)	θ value	1.06291 (rank : 38)
Query Neighborhood Hits	94	Target Neighborhood Hits	38	Shared Neighborhood Hits	28
SwissProt Accessions	P10265, Q9UKH6	Gene names
Domain Architecture
Description	HERV-K_5q33.3 provirus ancestral Pro protein (EC 3.4.23.-) (HERV-K10 Pro protein) (HERV-K107 Pro protein) (Protease) (Proteinase) (PR).

VPK12_HUMAN
NC score	0.166528 (rank : 20)	θ value	1.06291 (rank : 39)
Query Neighborhood Hits	94	Target Neighborhood Hits	37	Shared Neighborhood Hits	28
SwissProt Accessions	P63131, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Pro protein (EC 3.4.23.-) (HERV-K102 Pro protein) (HERV-K(III) Pro protein) (Protease) (Proteinase) (PR).

VPK2_HUMAN
NC score	0.164098 (rank : 21)	θ value	1.38821 (rank : 48)
Query Neighborhood Hits	94	Target Neighborhood Hits	39	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y6I0, Q9UKH5	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Pro protein (EC 3.4.23.-) (HERV- K(HML-2.HOM) Pro protein) (HERV-K108 Pro protein) (HERV-K(C7) Pro protein) (Protease) (Proteinase) (PR).

VPK6_HUMAN
NC score	0.162018 (rank : 22)	θ value	0.813845 (rank : 35)
Query Neighborhood Hits	94	Target Neighborhood Hits	35	Shared Neighborhood Hits	27
SwissProt Accessions	P63122	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Pro protein (EC 3.4.23.-) (HERV-K115 Pro protein) (Protease) (Proteinase) (PR).

VPK4_HUMAN
NC score	0.161930 (rank : 23)	θ value	0.813845 (rank : 34)
Query Neighborhood Hits	94	Target Neighborhood Hits	33	Shared Neighborhood Hits	27
SwissProt Accessions	P63127, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Pro protein (EC 3.4.23.-) (HERV-K109 Pro protein) (HERV-K(C6) Pro protein) (Protease) (Proteinase) (PR).

PINX1_HUMAN
NC score	0.154729 (rank : 24)	θ value	0.813845 (rank : 31)
Query Neighborhood Hits	94	Target Neighborhood Hits	65	Shared Neighborhood Hits	30
SwissProt Accessions	Q96BK5, Q7Z7J8, Q96QD7, Q9HBU7, Q9NWW2	Gene names	PINX1, LPTS
Domain Architecture
Description	Pin2-interacting protein X1 (TRF1-interacting protein 1) (Liver- related putative tumor suppressor) (67-11-3 protein).

SON_MOUSE
NC score	0.146773 (rank : 25)	θ value	0.00390308 (rank : 12)
Query Neighborhood Hits	94	Target Neighborhood Hits	957	Shared Neighborhood Hits	47
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

TFP11_HUMAN
NC score	0.145504 (rank : 26)	θ value	0.813845 (rank : 32)
Query Neighborhood Hits	94	Target Neighborhood Hits	73	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UBB9, O95908, Q5H8V8, Q9UGV7, Q9Y2Q8	Gene names	TFIP11
Domain Architecture
Description	Tuftelin-interacting protein 11.

RBM5_HUMAN
NC score	0.143010 (rank : 27)	θ value	0.163984 (rank : 15)
Query Neighborhood Hits	94	Target Neighborhood Hits	216	Shared Neighborhood Hits	40
SwissProt Accessions	P52756, Q93021, Q9BU14, Q9UKY8, Q9UL24	Gene names	RBM5
Domain Architecture
Description	RNA-binding protein 5 (RNA-binding motif protein 5) (Tumor suppressor LUCA15) (Protein G15) (NY-REN-9 antigen).

TFP11_MOUSE
NC score	0.142993 (rank : 28)	θ value	1.06291 (rank : 37)
Query Neighborhood Hits	94	Target Neighborhood Hits	95	Shared Neighborhood Hits	30
SwissProt Accessions	Q9ERA6, Q8VD06	Gene names	Tfip11, Tip39
Domain Architecture
Description	Tuftelin-interacting protein 11 (Tuftelin-interacting protein 39).

RBM5_MOUSE
NC score	0.142762 (rank : 29)	θ value	0.163984 (rank : 16)
Query Neighborhood Hits	94	Target Neighborhood Hits	216	Shared Neighborhood Hits	40
SwissProt Accessions	Q91YE7, Q3UZ19, Q99KV9	Gene names	Rbm5, Luca15
Domain Architecture	No domain graphic available
Description	RNA-binding protein 5 (RNA-binding motif protein 5) (Tumor suppressor LUCA15).

RBM10_HUMAN
NC score	0.112034 (rank : 30)	θ value	3.0926 (rank : 59)
Query Neighborhood Hits	94	Target Neighborhood Hits	204	Shared Neighborhood Hits	36
SwissProt Accessions	P98175, Q14136	Gene names	RBM10, DXS8237E, KIAA0122
Domain Architecture
Description	RNA-binding protein 10 (RNA-binding motif protein 10).

SON_HUMAN
NC score	0.101458 (rank : 31)	θ value	0.00390308 (rank : 11)
Query Neighborhood Hits	94	Target Neighborhood Hits	1568	Shared Neighborhood Hits	46
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

RNPC2_MOUSE
NC score	0.096355 (rank : 32)	θ value	0.365318 (rank : 21)
Query Neighborhood Hits	94	Target Neighborhood Hits	251	Shared Neighborhood Hits	27
SwissProt Accessions	Q8VH51, Q99KV0	Gene names	Rnpc2, Caper
Domain Architecture
Description	RNA-binding region-containing protein 2 (Coactivator of activating protein 1 and estrogen receptors) (Coactivator of AP-1 and ERs) (Transcription coactivator CAPER).

RNPC2_HUMAN
NC score	0.096232 (rank : 33)	θ value	0.365318 (rank : 20)
Query Neighborhood Hits	94	Target Neighborhood Hits	250	Shared Neighborhood Hits	26
SwissProt Accessions	Q14498, Q14499	Gene names	RNPC2, HCC1
Domain Architecture
Description	RNA-binding region-containing protein 2 (Hepatocellular carcinoma protein 1) (Splicing factor HCC1).

AGGF1_MOUSE
NC score	0.094655 (rank : 34)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	94	Target Neighborhood Hits	155	Shared Neighborhood Hits	31
SwissProt Accessions	Q7TN31, Q8R2S6, Q9CQR9, Q9CU87, Q9D768	Gene names	Aggf1, Vg5q
Domain Architecture
Description	Angiogenic factor with G patch and FHA domains 1 (Angiogenic factor VG5Q) (mVG5Q).

AGGF1_HUMAN
NC score	0.090672 (rank : 35)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	94	Target Neighborhood Hits	271	Shared Neighborhood Hits	32
SwissProt Accessions	Q8N302, O00581, Q53YS3, Q9BU84, Q9NW66	Gene names	AGGF1, VG5Q
Domain Architecture
Description	Angiogenic factor with G patch and FHA domains 1 (Angiogenic factor VG5Q) (Vasculogenesis gene on 5q protein) (hVG5Q).

UHMK1_MOUSE
NC score	0.087215 (rank : 36)	θ value	0.000158464 (rank : 6)
Query Neighborhood Hits	94	Target Neighborhood Hits	809	Shared Neighborhood Hits	14
SwissProt Accessions	P97343, Q61775, Q9CYT1	Gene names	Uhmk1, Kis, Kist
Domain Architecture
Description	Serine/threonine-protein kinase Kist (EC 2.7.11.1) (Kinase interacting with stathmin) (U2AF homology motif kinase 1).

UHMK1_HUMAN
NC score	0.086742 (rank : 37)	θ value	0.000158464 (rank : 5)
Query Neighborhood Hits	94	Target Neighborhood Hits	808	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TAS1, Q96C22	Gene names	UHMK1, KIS, KIST
Domain Architecture
Description	Serine/threonine-protein kinase Kist (EC 2.7.11.1) (Kinase interacting with stathmin) (U2AF homology motif kinase 1).

PABP5_HUMAN
NC score	0.074063 (rank : 38)	θ value	0.62314 (rank : 27)
Query Neighborhood Hits	94	Target Neighborhood Hits	212	Shared Neighborhood Hits	23
SwissProt Accessions	Q96DU9, Q6P529, Q9UFE5	Gene names	PABPC5, PABP5
Domain Architecture
Description	Polyadenylate-binding protein 5 (Poly(A)-binding protein 5) (PABP 5).

PABP4_HUMAN
NC score	0.072111 (rank : 39)	θ value	1.81305 (rank : 49)
Query Neighborhood Hits	94	Target Neighborhood Hits	268	Shared Neighborhood Hits	29
SwissProt Accessions	Q13310, Q6P0N3	Gene names	PABPC4, APP1, PABP4
Domain Architecture
Description	Polyadenylate-binding protein 4 (Poly(A)-binding protein 4) (PABP 4) (Inducible poly(A)-binding protein) (iPABP) (Activated-platelet protein 1) (APP-1).

PRGC1_MOUSE
NC score	0.068502 (rank : 40)	θ value	0.62314 (rank : 28)
Query Neighborhood Hits	94	Target Neighborhood Hits	238	Shared Neighborhood Hits	16
SwissProt Accessions	O70343	Gene names	Ppargc1a, Pgc1, Pgc1a, Ppargc1
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPAR gamma coactivator 1-alpha) (PPARGC-1-alpha) (PGC-1-alpha).

RB15B_MOUSE
NC score	0.067696 (rank : 41)	θ value	1.38821 (rank : 47)
Query Neighborhood Hits	94	Target Neighborhood Hits	284	Shared Neighborhood Hits	18
SwissProt Accessions	Q6PHZ5, Q8C6G2	Gene names	Rbm15b
Domain Architecture	No domain graphic available
Description	Putative RNA-binding protein 15B (RNA-binding motif protein 15B).

SF04_HUMAN
NC score	0.066586 (rank : 42)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	94	Target Neighborhood Hits	83	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IWZ8, O60378, Q6P3X9, Q8TCQ4, Q8WWT4, Q8WWT5, Q9NTG3	Gene names	SF4
Domain Architecture	No domain graphic available
Description	Splicing factor 4 (RNA-binding protein RBP).

RBBP6_HUMAN
NC score	0.066449 (rank : 43)	θ value	0.365318 (rank : 19)
Query Neighborhood Hits	94	Target Neighborhood Hits	1135	Shared Neighborhood Hits	25
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RB15B_HUMAN
NC score	0.065259 (rank : 44)	θ value	1.38821 (rank : 46)
Query Neighborhood Hits	94	Target Neighborhood Hits	251	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NDT2, Q6QE19, Q9BV96	Gene names	RBM15B
Domain Architecture	No domain graphic available
Description	Putative RNA-binding protein 15B (RNA-binding motif protein 15B).

U2AFL_MOUSE
NC score	0.061533 (rank : 45)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	94	Target Neighborhood Hits	389	Shared Neighborhood Hits	22
SwissProt Accessions	Q64707	Gene names	Zrsr1, Sp2, Sp2-7, U2af1-rs1, U2af1l1
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 1 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1) (SP2).

PABP1_MOUSE
NC score	0.060842 (rank : 46)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	94	Target Neighborhood Hits	278	Shared Neighborhood Hits	30
SwissProt Accessions	P29341	Gene names	Pabpc1, Pabp1
Domain Architecture
Description	Polyadenylate-binding protein 1 (Poly(A)-binding protein 1) (PABP 1).

U2AFL_HUMAN
NC score	0.060592 (rank : 47)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	94	Target Neighborhood Hits	503	Shared Neighborhood Hits	21
SwissProt Accessions	Q15695, Q13570	Gene names	ZRSR1, U2AF1-RS1, U2AF1L1, U2AF1RS1, U2AFBPL
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 1 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1).

CSTF2_MOUSE
NC score	0.059888 (rank : 48)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	94	Target Neighborhood Hits	255	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BIQ5, Q8K1Y6, Q9ERC2	Gene names	Cstf2
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 64 kDa subunit (CSTF 64 kDa subunit) (CF-1 64 kDa subunit) (CstF-64).

CSTFT_MOUSE
NC score	0.059861 (rank : 49)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	94	Target Neighborhood Hits	356	Shared Neighborhood Hits	20
SwissProt Accessions	Q8C7E9, Q6A016, Q8BHH7, Q8C3W7, Q8R2Y1, Q9EPU3	Gene names	Cstf2t, Kiaa0689
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 64 kDa subunit, tau variant (CSTF 64 kDa subunit, tau variant) (CF-1 64 kDa subunit, tau variant) (TauCstF-64).

SFR14_MOUSE
NC score	0.059580 (rank : 50)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	94	Target Neighborhood Hits	238	Shared Neighborhood Hits	28
SwissProt Accessions	Q8CH09, Q6PG19, Q80UY8, Q8BY32, Q8CFM0	Gene names	Sfrs14
Domain Architecture	No domain graphic available
Description	Putative splicing factor, arginine/serine-rich 14 (Arginine/serine- rich-splicing factor 14).

U2AFM_HUMAN
NC score	0.059167 (rank : 51)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	94	Target Neighborhood Hits	577	Shared Neighborhood Hits	24
SwissProt Accessions	Q15696	Gene names	ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (NY-REN-20 antigen).

CSTF2_HUMAN
NC score	0.058567 (rank : 52)	θ value	8.99809 (rank : 83)
Query Neighborhood Hits	94	Target Neighborhood Hits	296	Shared Neighborhood Hits	23
SwissProt Accessions	P33240, Q5H951, Q6LA74, Q8N502	Gene names	CSTF2
Domain Architecture
Description	Cleavage stimulation factor 64 kDa subunit (CSTF 64 kDa subunit) (CF-1 64 kDa subunit) (CstF-64).

GPTC2_HUMAN
NC score	0.058066 (rank : 53)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	94	Target Neighborhood Hits	50	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NW75, Q86YE7	Gene names	GPATC2
Domain Architecture
Description	G patch domain-containing protein 2.

RBM12_MOUSE
NC score	0.057239 (rank : 54)	θ value	3.0926 (rank : 61)
Query Neighborhood Hits	94	Target Neighborhood Hits	313	Shared Neighborhood Hits	18
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

RBM12_HUMAN
NC score	0.056705 (rank : 55)	θ value	3.0926 (rank : 60)
Query Neighborhood Hits	94	Target Neighborhood Hits	298	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NTZ6, O94865, Q8N3B1, Q9H196	Gene names	RBM12, KIAA0765
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

CSTFT_HUMAN
NC score	0.056502 (rank : 56)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	94	Target Neighborhood Hits	292	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H0L4, O75174, Q53HK6, Q7LGE8, Q8N6T1	Gene names	CSTF2T, KIAA0689
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 64 kDa subunit, tau variant (CSTF 64 kDa subunit, tau variant) (CF-1 64 kDa subunit, tau variant) (TauCstF-64).

RBM23_HUMAN
NC score	0.055298 (rank : 57)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	94	Target Neighborhood Hits	235	Shared Neighborhood Hits	20
SwissProt Accessions	Q86U06, Q8ND16, Q8TB88, Q8WY40, Q9BUJ1, Q9NVV7	Gene names	RBM23, RNPC4
Domain Architecture
Description	Probable RNA-binding protein 23 (RNA-binding motif protein 23) (RNA- binding region-containing protein 4) (Splicing factor SF2).

NKRF_HUMAN
NC score	0.055050 (rank : 58)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	94	Target Neighborhood Hits	57	Shared Neighborhood Hits	29
SwissProt Accessions	O15226, Q9UJ91	Gene names	NKRF, ITBA4, NRF
Domain Architecture
Description	NF-kappa-B-repressing factor (NFKB-repressing factor) (Transcription factor NRF) (ITBA4 protein).

MAN1_HUMAN
NC score	0.054906 (rank : 59)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	94	Target Neighborhood Hits	37	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y2U8, Q9NT47, Q9NYA5	Gene names	LEMD3, MAN1
Domain Architecture
Description	Inner nuclear membrane protein Man1 (LEM domain-containing protein 3).

U2AFM_MOUSE
NC score	0.054742 (rank : 60)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	94	Target Neighborhood Hits	543	Shared Neighborhood Hits	21
SwissProt Accessions	Q62377	Gene names	Zrsr2, U2af1-rs2, U2af1l2, U2af1rs2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2).

NKRF_MOUSE
NC score	0.054450 (rank : 61)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	94	Target Neighborhood Hits	67	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BY02, Q8BJU5, Q9CRL2	Gene names	Nkrf, Nrf
Domain Architecture
Description	NF-kappa-B-repressing factor (NFKB-repressing factor) (Transcription factor NRF).

RBMX2_HUMAN
NC score	0.054367 (rank : 62)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	94	Target Neighborhood Hits	351	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y388, Q5JY82, Q9Y3I8	Gene names	RBMX2
Domain Architecture
Description	RNA-binding motif protein, X-linked 2.

SF04_MOUSE
NC score	0.054161 (rank : 63)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	94	Target Neighborhood Hits	95	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CH02, Q8R094	Gene names	Sf4
Domain Architecture	No domain graphic available
Description	Splicing factor 4.

GSCR2_HUMAN
NC score	0.053419 (rank : 64)	θ value	3.0926 (rank : 55)
Query Neighborhood Hits	94	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NZM5, Q9BTC6, Q9HAX6, Q9NPP1, Q9NPR4, Q9UFI2	Gene names	GLTSCR2
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 2 protein (p60).

PABP3_HUMAN
NC score	0.053396 (rank : 65)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	94	Target Neighborhood Hits	259	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H361, Q8NHV0, Q9H086	Gene names	PABPC3, PABP3, PABPL3
Domain Architecture
Description	Polyadenylate-binding protein 3 (Poly(A)-binding protein 3) (PABP 3) (Testis-specific poly(A)-binding protein).

GPTC2_MOUSE
NC score	0.053286 (rank : 66)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	94	Target Neighborhood Hits	61	Shared Neighborhood Hits	28
SwissProt Accessions	Q7TQC7, Q8BNJ9, Q8BPM1, Q8CDH9	Gene names	Gpatc2
Domain Architecture
Description	G patch domain-containing protein 2.

PABP1_HUMAN
NC score	0.053237 (rank : 67)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	94	Target Neighborhood Hits	269	Shared Neighborhood Hits	23
SwissProt Accessions	P11940, Q15097, Q93004	Gene names	PABPC1, PAB1, PABP1, PABPC2
Domain Architecture
Description	Polyadenylate-binding protein 1 (Poly(A)-binding protein 1) (PABP 1).

TIA1_HUMAN
NC score	0.053116 (rank : 68)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	94	Target Neighborhood Hits	236	Shared Neighborhood Hits	25
SwissProt Accessions	P31483	Gene names	TIA1
Domain Architecture	No domain graphic available
Description	Nucleolysin TIA-1 isoform p40 (RNA-binding protein TIA-1) (p40-TIA-1) [Contains: Nucleolysin TIA-1 isoform p15 (p15-TIA-1)].

GPTC3_MOUSE
NC score	0.052779 (rank : 69)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	94	Target Neighborhood Hits	52	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BIY1	Gene names	Gpatc3
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 3.

TIA1_MOUSE
NC score	0.052571 (rank : 70)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	94	Target Neighborhood Hits	241	Shared Neighborhood Hits	26
SwissProt Accessions	P52912	Gene names	Tia1, Tia
Domain Architecture
Description	Nucleolysin TIA-1 (RNA-binding protein TIA-1).

WWC3_HUMAN
NC score	0.051395 (rank : 71)	θ value	1.06291 (rank : 41)
Query Neighborhood Hits	94	Target Neighborhood Hits	193	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ULE0, Q659C1, Q9BTQ1	Gene names	WWC3, KIAA1280
Domain Architecture	No domain graphic available
Description	WWC family member 3.

RBMX2_MOUSE
NC score	0.050890 (rank : 72)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	94	Target Neighborhood Hits	287	Shared Neighborhood Hits	25
SwissProt Accessions	Q8R0F5, Q3TI42	Gene names	Rbmx2
Domain Architecture
Description	RNA-binding motif protein, X-linked 2.

TXND2_MOUSE
NC score	0.049380 (rank : 73)	θ value	0.365318 (rank : 22)
Query Neighborhood Hits	94	Target Neighborhood Hits	828	Shared Neighborhood Hits	17
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

JHD1B_MOUSE
NC score	0.047697 (rank : 74)	θ value	0.62314 (rank : 26)
Query Neighborhood Hits	94	Target Neighborhood Hits	214	Shared Neighborhood Hits	7
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

DNJC8_HUMAN
NC score	0.047272 (rank : 75)	θ value	3.0926 (rank : 52)
Query Neighborhood Hits	94	Target Neighborhood Hits	380	Shared Neighborhood Hits	12
SwissProt Accessions	O75937, Q6IBA4, Q8N4Z5, Q9P051, Q9P067	Gene names	DNAJC8, SPF31
Domain Architecture
Description	DnaJ homolog subfamily C member 8 (Splicing protein spf31).

JHD1B_HUMAN
NC score	0.047195 (rank : 76)	θ value	1.06291 (rank : 36)
Query Neighborhood Hits	94	Target Neighborhood Hits	178	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NHM5, Q8NCI2, Q96HC7, Q96SL0, Q96T03, Q9NS96, Q9UF75	Gene names	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (Protein JEMMA) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (CXXC-type zinc finger protein 2) (Protein-containing CXXC domain 2).

DNJC8_MOUSE
NC score	0.047020 (rank : 77)	θ value	3.0926 (rank : 53)
Query Neighborhood Hits	94	Target Neighborhood Hits	392	Shared Neighborhood Hits	11
SwissProt Accessions	Q6NZB0, Q6PG72, Q8C2M6	Gene names	Dnajc8
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 8.

MINT_MOUSE
NC score	0.042875 (rank : 78)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	94	Target Neighborhood Hits	1514	Shared Neighborhood Hits	38
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

DNJC7_MOUSE
NC score	0.038476 (rank : 79)	θ value	1.38821 (rank : 43)
Query Neighborhood Hits	94	Target Neighborhood Hits	211	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QYI3, Q3TKR1, Q8BPG3, Q8CIL2, Q9CT29, Q9D026	Gene names	Dnajc7, Ttc2
Domain Architecture
Description	DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2) (MDj11).

DNJC7_HUMAN
NC score	0.038155 (rank : 80)	θ value	1.38821 (rank : 42)
Query Neighborhood Hits	94	Target Neighborhood Hits	212	Shared Neighborhood Hits	7
SwissProt Accessions	Q99615	Gene names	DNAJC7, TPR2, TTC2
Domain Architecture
Description	DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2).

ENAM_HUMAN
NC score	0.034962 (rank : 81)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	94	Target Neighborhood Hits	227	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NRM1, Q9H3D1	Gene names	ENAM
Domain Architecture
Description	Enamelin precursor.

CCNK_MOUSE
NC score	0.033608 (rank : 82)	θ value	6.88961 (rank : 72)
Query Neighborhood Hits	94	Target Neighborhood Hits	350	Shared Neighborhood Hits	9
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

ZN318_HUMAN
NC score	0.032517 (rank : 83)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	94	Target Neighborhood Hits	497	Shared Neighborhood Hits	14
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

SRRM1_HUMAN
NC score	0.031235 (rank : 84)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	94	Target Neighborhood Hits	690	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

CASP8_MOUSE
NC score	0.027723 (rank : 85)	θ value	2.36792 (rank : 50)
Query Neighborhood Hits	94	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	O89110, O35669	Gene names	Casp8
Domain Architecture
Description	Caspase-8 precursor (EC 3.4.22.-) (CASP-8) [Contains: Caspase-8 subunit p18; Caspase-8 subunit p10].

MYCB2_HUMAN
NC score	0.027520 (rank : 86)	θ value	2.36792 (rank : 51)
Query Neighborhood Hits	94	Target Neighborhood Hits	390	Shared Neighborhood Hits	10
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

LPIN1_HUMAN
NC score	0.026174 (rank : 87)	θ value	3.0926 (rank : 56)
Query Neighborhood Hits	94	Target Neighborhood Hits	36	Shared Neighborhood Hits	6
SwissProt Accessions	Q14693	Gene names	LPIN1, KIAA0188
Domain Architecture
Description	Lipin-1.

TRDN_HUMAN
NC score	0.025732 (rank : 88)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	94	Target Neighborhood Hits	542	Shared Neighborhood Hits	12
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

MAMC1_MOUSE
NC score	0.024257 (rank : 89)	θ value	1.38821 (rank : 44)
Query Neighborhood Hits	94	Target Neighborhood Hits	357	Shared Neighborhood Hits	4
SwissProt Accessions	P60755	Gene names	Mamdc1, Mdga2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

ELOA1_HUMAN
NC score	0.021475 (rank : 90)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	94	Target Neighborhood Hits	388	Shared Neighborhood Hits	13
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

ITSN1_MOUSE
NC score	0.021342 (rank : 91)	θ value	0.365318 (rank : 18)
Query Neighborhood Hits	94	Target Neighborhood Hits	1669	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

MAMC1_HUMAN
NC score	0.020987 (rank : 92)	θ value	3.0926 (rank : 57)
Query Neighborhood Hits	94	Target Neighborhood Hits	357	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z553	Gene names	MAMDC1, MDGA2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

TOR3A_HUMAN
NC score	0.020442 (rank : 93)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	94	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H497, Q5M7Y7, Q8WVA7, Q8WWM2, Q9H495, Q9H6E7	Gene names	TOR3A, ADIR
Domain Architecture	No domain graphic available
Description	Torsin-3A precursor (Torsin family 3 member A) (ATP-dependent interferon-responsive protein).

MAGI2_HUMAN
NC score	0.019933 (rank : 94)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	94	Target Neighborhood Hits	373	Shared Neighborhood Hits	7
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

GDF2_HUMAN
NC score	0.018302 (rank : 95)	θ value	3.0926 (rank : 54)
Query Neighborhood Hits	94	Target Neighborhood Hits	77	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UK05, Q9Y571	Gene names	GDF2, BMP9
Domain Architecture
Description	Growth/differentiation factor 2 precursor (GDF-2) (Bone morphogenetic protein 9) (BMP-9).

MYOC_HUMAN
NC score	0.017854 (rank : 96)	θ value	4.03905 (rank : 66)
Query Neighborhood Hits	94	Target Neighborhood Hits	489	Shared Neighborhood Hits	6
SwissProt Accessions	Q99972, O00620, Q7Z6Q9	Gene names	MYOC, GLC1A, TIGR
Domain Architecture
Description	Myocilin precursor (Trabecular meshwork-induced glucocorticoid response protein).

MAGI2_MOUSE
NC score	0.015450 (rank : 97)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	94	Target Neighborhood Hits	370	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

CTNA3_MOUSE
NC score	0.014032 (rank : 98)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	94	Target Neighborhood Hits	55	Shared Neighborhood Hits	2
SwissProt Accessions	Q65CL1, Q3UQ61, Q8C0N3	Gene names	Ctnna3, Catna3
Domain Architecture	No domain graphic available
Description	Catenin alpha-3 (Alpha T-catenin) (Cadherin-associated protein).

BRD8_HUMAN
NC score	0.013038 (rank : 99)	θ value	8.99809 (rank : 82)
Query Neighborhood Hits	94	Target Neighborhood Hits	292	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

PCD15_MOUSE
NC score	0.012213 (rank : 100)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	94	Target Neighborhood Hits	262	Shared Neighborhood Hits	6
SwissProt Accessions	Q99PJ1	Gene names	Pcdh15
Domain Architecture
Description	Protocadherin-15 precursor.

RIMS2_HUMAN
NC score	0.012211 (rank : 101)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	94	Target Neighborhood Hits	342	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

MYH9_HUMAN
NC score	0.011871 (rank : 102)	θ value	1.38821 (rank : 45)
Query Neighborhood Hits	94	Target Neighborhood Hits	1762	Shared Neighborhood Hits	15
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH9_MOUSE
NC score	0.011699 (rank : 103)	θ value	3.0926 (rank : 58)
Query Neighborhood Hits	94	Target Neighborhood Hits	1829	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

TUFT1_MOUSE
NC score	0.010329 (rank : 104)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	94	Target Neighborhood Hits	732	Shared Neighborhood Hits	9
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

ANK2_HUMAN
NC score	0.009255 (rank : 105)	θ value	6.88961 (rank : 71)
Query Neighborhood Hits	94	Target Neighborhood Hits	1615	Shared Neighborhood Hits	25
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ZYX_MOUSE
NC score	0.008774 (rank : 106)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	94	Target Neighborhood Hits	347	Shared Neighborhood Hits	4
SwissProt Accessions	Q62523, P70461	Gene names	Zyx
Domain Architecture
Description	Zyxin.

SEPT4_HUMAN
NC score	0.008580 (rank : 107)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	94	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	O43236, Q9UM58	Gene names	SEPT4, PNUTL2
Domain Architecture
Description	Septin-4 (Peanut-like protein 2) (Brain protein H5) (Cell division control-related protein 2) (hCDCREL-2) (Bradeion beta) (CE5B3 beta) (Cerebral protein 7).

ZFP64_MOUSE
NC score	-0.001684 (rank : 108)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	94	Target Neighborhood Hits	733	Shared Neighborhood Hits	3
SwissProt Accessions	Q99KE8, P97365, Q9CWR3	Gene names	Zfp64
Domain Architecture	No domain graphic available
Description	Zinc finger protein 64 (Zfp-64).

PRDM9_HUMAN
NC score	-0.002113 (rank : 109)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	94	Target Neighborhood Hits	750	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NQV7	Gene names	PRDM9, PFM6
Domain Architecture
Description	PR domain zinc finger protein 9 (PR domain-containing protein 9).