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Network neighborhood for query Sequence : U520_HUMAN

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U520_HUMAN
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HELC1_HUMAN
θ value	0 (rank : 1)	NC score	0.952338 (rank : 2)
Query Neighborhood Hits	88	Target Neighborhood Hits	71	Shared Neighborhood Hits	37
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

U520_HUMAN
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	88	Target Neighborhood Hits	88	Shared Neighborhood Hits	88
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

SKIV2_HUMAN
θ value	1.05554e-24 (rank : 3)	NC score	0.560851 (rank : 3)
Query Neighborhood Hits	88	Target Neighborhood Hits	45	Shared Neighborhood Hits	15
SwissProt Accessions	Q15477, O15005, Q12902, Q15476	Gene names	SKIV2L, DDX13, SKI2W, SKIV2, W
Domain Architecture
Description	Helicase SKI2W (EC 3.6.1.-) (Helicase-like protein) (HLP).

SK2L2_MOUSE
θ value	3.51386e-20 (rank : 4)	NC score	0.531526 (rank : 4)
Query Neighborhood Hits	88	Target Neighborhood Hits	45	Shared Neighborhood Hits	15
SwissProt Accessions	Q9CZU3	Gene names	Skiv2l2
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

SK2L2_HUMAN
θ value	7.82807e-20 (rank : 5)	NC score	0.530507 (rank : 5)
Query Neighborhood Hits	88	Target Neighborhood Hits	36	Shared Neighborhood Hits	15
SwissProt Accessions	P42285, Q8TAG2	Gene names	SKIV2L2, KIAA0052
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

SEC63_HUMAN
θ value	3.18553e-13 (rank : 6)	NC score	0.245601 (rank : 6)
Query Neighborhood Hits	88	Target Neighborhood Hits	586	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

SEC63_MOUSE
θ value	7.09661e-13 (rank : 7)	NC score	0.244476 (rank : 7)
Query Neighborhood Hits	88	Target Neighborhood Hits	601	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

DDX46_HUMAN
θ value	0.000121331 (rank : 8)	NC score	0.178506 (rank : 24)
Query Neighborhood Hits	88	Target Neighborhood Hits	357	Shared Neighborhood Hits	53
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX46_MOUSE
θ value	0.000121331 (rank : 9)	NC score	0.178376 (rank : 25)
Query Neighborhood Hits	88	Target Neighborhood Hits	358	Shared Neighborhood Hits	53
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX52_MOUSE
θ value	0.000158464 (rank : 10)	NC score	0.189152 (rank : 19)
Query Neighborhood Hits	88	Target Neighborhood Hits	101	Shared Neighborhood Hits	48
SwissProt Accessions	Q8K301, Q8BV29	Gene names	Ddx52, Rok1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

RECQ5_HUMAN
θ value	0.000158464 (rank : 11)	NC score	0.206708 (rank : 9)
Query Neighborhood Hits	88	Target Neighborhood Hits	390	Shared Neighborhood Hits	39
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

DDX51_MOUSE
θ value	0.00035302 (rank : 12)	NC score	0.180040 (rank : 22)
Query Neighborhood Hits	88	Target Neighborhood Hits	130	Shared Neighborhood Hits	47
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX55_HUMAN
θ value	0.000602161 (rank : 13)	NC score	0.159881 (rank : 32)
Query Neighborhood Hits	88	Target Neighborhood Hits	122	Shared Neighborhood Hits	43
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DICER_MOUSE
θ value	0.00102713 (rank : 14)	NC score	0.206236 (rank : 10)
Query Neighborhood Hits	88	Target Neighborhood Hits	140	Shared Neighborhood Hits	43
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

DDX52_HUMAN
θ value	0.00175202 (rank : 15)	NC score	0.187228 (rank : 20)
Query Neighborhood Hits	88	Target Neighborhood Hits	107	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX55_MOUSE
θ value	0.00175202 (rank : 16)	NC score	0.157942 (rank : 34)
Query Neighborhood Hits	88	Target Neighborhood Hits	111	Shared Neighborhood Hits	44
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX43_HUMAN
θ value	0.00509761 (rank : 17)	NC score	0.157212 (rank : 36)
Query Neighborhood Hits	88	Target Neighborhood Hits	120	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

FANCM_MOUSE
θ value	0.00869519 (rank : 18)	NC score	0.200565 (rank : 12)
Query Neighborhood Hits	88	Target Neighborhood Hits	177	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

DDX10_HUMAN
θ value	0.0113563 (rank : 19)	NC score	0.153939 (rank : 38)
Query Neighborhood Hits	88	Target Neighborhood Hits	210	Shared Neighborhood Hits	44
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX58_HUMAN
θ value	0.0113563 (rank : 20)	NC score	0.195034 (rank : 15)
Query Neighborhood Hits	88	Target Neighborhood Hits	105	Shared Neighborhood Hits	35
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

DICER_HUMAN
θ value	0.0113563 (rank : 21)	NC score	0.193987 (rank : 17)
Query Neighborhood Hits	88	Target Neighborhood Hits	126	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

RECQ4_MOUSE
θ value	0.0113563 (rank : 22)	NC score	0.208678 (rank : 8)
Query Neighborhood Hits	88	Target Neighborhood Hits	206	Shared Neighborhood Hits	45
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

DDX58_MOUSE
θ value	0.0148317 (rank : 23)	NC score	0.199517 (rank : 13)
Query Neighborhood Hits	88	Target Neighborhood Hits	99	Shared Neighborhood Hits	34
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

WRN_HUMAN
θ value	0.0148317 (rank : 24)	NC score	0.198409 (rank : 14)
Query Neighborhood Hits	88	Target Neighborhood Hits	132	Shared Neighborhood Hits	45
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

DDX4_HUMAN
θ value	0.0193708 (rank : 25)	NC score	0.159273 (rank : 33)
Query Neighborhood Hits	88	Target Neighborhood Hits	123	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

IFIH1_MOUSE
θ value	0.0193708 (rank : 26)	NC score	0.183148 (rank : 21)
Query Neighborhood Hits	88	Target Neighborhood Hits	126	Shared Neighborhood Hits	43
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

BLM_HUMAN
θ value	0.0252991 (rank : 27)	NC score	0.155505 (rank : 37)
Query Neighborhood Hits	88	Target Neighborhood Hits	148	Shared Neighborhood Hits	36
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

DDX4_MOUSE
θ value	0.0431538 (rank : 28)	NC score	0.157596 (rank : 35)
Query Neighborhood Hits	88	Target Neighborhood Hits	100	Shared Neighborhood Hits	46
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

FANCM_HUMAN
θ value	0.0431538 (rank : 29)	NC score	0.194200 (rank : 16)
Query Neighborhood Hits	88	Target Neighborhood Hits	210	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

DDX18_MOUSE
θ value	0.0563607 (rank : 30)	NC score	0.145476 (rank : 41)
Query Neighborhood Hits	88	Target Neighborhood Hits	115	Shared Neighborhood Hits	39
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

DDX31_HUMAN
θ value	0.0736092 (rank : 31)	NC score	0.163033 (rank : 31)
Query Neighborhood Hits	88	Target Neighborhood Hits	132	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

DDX51_HUMAN
θ value	0.0961366 (rank : 32)	NC score	0.175661 (rank : 28)
Query Neighborhood Hits	88	Target Neighborhood Hits	332	Shared Neighborhood Hits	48
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

RECQ1_HUMAN
θ value	0.0961366 (rank : 33)	NC score	0.189869 (rank : 18)
Query Neighborhood Hits	88	Target Neighborhood Hits	100	Shared Neighborhood Hits	43
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

IFIH1_HUMAN
θ value	0.125558 (rank : 34)	NC score	0.170753 (rank : 29)
Query Neighborhood Hits	88	Target Neighborhood Hits	96	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

LGP2_MOUSE
θ value	0.163984 (rank : 35)	NC score	0.179113 (rank : 23)
Query Neighborhood Hits	88	Target Neighborhood Hits	86	Shared Neighborhood Hits	37
SwissProt Accessions	Q99J87, Q9D1X4	Gene names	Lgp2, D11lgp2e
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2).

DDX49_MOUSE
θ value	0.21417 (rank : 36)	NC score	0.148771 (rank : 40)
Query Neighborhood Hits	88	Target Neighborhood Hits	119	Shared Neighborhood Hits	48
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

RECQ1_MOUSE
θ value	0.21417 (rank : 37)	NC score	0.177212 (rank : 26)
Query Neighborhood Hits	88	Target Neighborhood Hits	95	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

COG6_HUMAN
θ value	0.279714 (rank : 38)	NC score	0.058623 (rank : 95)
Query Neighborhood Hits	88	Target Neighborhood Hits	118	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y2V7, Q5T0U1, Q9ULT5	Gene names	COG6, KIAA1134
Domain Architecture
Description	Conserved oligomeric Golgi complex component 6.

GOGB1_HUMAN
θ value	0.279714 (rank : 39)	NC score	0.020697 (rank : 104)
Query Neighborhood Hits	88	Target Neighborhood Hits	2297	Shared Neighborhood Hits	28
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

WRN_MOUSE
θ value	0.279714 (rank : 40)	NC score	0.175935 (rank : 27)
Query Neighborhood Hits	88	Target Neighborhood Hits	295	Shared Neighborhood Hits	45
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

DDX49_HUMAN
θ value	0.47712 (rank : 41)	NC score	0.149134 (rank : 39)
Query Neighborhood Hits	88	Target Neighborhood Hits	223	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

RECQ4_HUMAN
θ value	0.47712 (rank : 42)	NC score	0.204930 (rank : 11)
Query Neighborhood Hits	88	Target Neighborhood Hits	177	Shared Neighborhood Hits	47
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

DDX47_HUMAN
θ value	0.62314 (rank : 43)	NC score	0.142516 (rank : 45)
Query Neighborhood Hits	88	Target Neighborhood Hits	97	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

KIF5C_HUMAN
θ value	0.62314 (rank : 44)	NC score	0.015552 (rank : 111)
Query Neighborhood Hits	88	Target Neighborhood Hits	974	Shared Neighborhood Hits	17
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

DDX28_MOUSE
θ value	0.813845 (rank : 45)	NC score	0.139341 (rank : 50)
Query Neighborhood Hits	88	Target Neighborhood Hits	112	Shared Neighborhood Hits	46
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX47_MOUSE
θ value	0.813845 (rank : 46)	NC score	0.142135 (rank : 48)
Query Neighborhood Hits	88	Target Neighborhood Hits	97	Shared Neighborhood Hits	44
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

VPS72_MOUSE
θ value	0.813845 (rank : 47)	NC score	0.044483 (rank : 97)
Query Neighborhood Hits	88	Target Neighborhood Hits	286	Shared Neighborhood Hits	6
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

CYTSA_HUMAN
θ value	1.06291 (rank : 48)	NC score	0.020224 (rank : 105)
Query Neighborhood Hits	88	Target Neighborhood Hits	1138	Shared Neighborhood Hits	20
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

DDX54_MOUSE
θ value	1.06291 (rank : 49)	NC score	0.144441 (rank : 42)
Query Neighborhood Hits	88	Target Neighborhood Hits	124	Shared Neighborhood Hits	46
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

DDX21_MOUSE
θ value	1.38821 (rank : 50)	NC score	0.134863 (rank : 52)
Query Neighborhood Hits	88	Target Neighborhood Hits	350	Shared Neighborhood Hits	46
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

LEO1_MOUSE
θ value	1.38821 (rank : 51)	NC score	0.029873 (rank : 101)
Query Neighborhood Hits	88	Target Neighborhood Hits	946	Shared Neighborhood Hits	14
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

THNSL_MOUSE
θ value	1.38821 (rank : 52)	NC score	0.036823 (rank : 100)
Query Neighborhood Hits	88	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BH55	Gene names	Thnsl1
Domain Architecture	No domain graphic available
Description	Threonine synthase-like 1.

DDX54_HUMAN
θ value	1.81305 (rank : 53)	NC score	0.143968 (rank : 44)
Query Neighborhood Hits	88	Target Neighborhood Hits	170	Shared Neighborhood Hits	46
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

ERC2_MOUSE
θ value	2.36792 (rank : 54)	NC score	0.020181 (rank : 106)
Query Neighborhood Hits	88	Target Neighborhood Hits	1166	Shared Neighborhood Hits	20
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

RB6I2_MOUSE
θ value	2.36792 (rank : 55)	NC score	0.019662 (rank : 107)
Query Neighborhood Hits	88	Target Neighborhood Hits	1433	Shared Neighborhood Hits	24
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

BLM_MOUSE
θ value	3.0926 (rank : 56)	NC score	0.144157 (rank : 43)
Query Neighborhood Hits	88	Target Neighborhood Hits	108	Shared Neighborhood Hits	35
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

CCR4_MOUSE
θ value	3.0926 (rank : 57)	NC score	0.001222 (rank : 132)
Query Neighborhood Hits	88	Target Neighborhood Hits	728	Shared Neighborhood Hits	2
SwissProt Accessions	P51680	Gene names	Ccr4, Cmkbr4
Domain Architecture
Description	C-C chemokine receptor type 4 (C-C CKR-4) (CC-CKR-4) (CCR-4) (CCR4).

DDX21_HUMAN
θ value	3.0926 (rank : 58)	NC score	0.141538 (rank : 49)
Query Neighborhood Hits	88	Target Neighborhood Hits	308	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX24_HUMAN
θ value	3.0926 (rank : 59)	NC score	0.131961 (rank : 62)
Query Neighborhood Hits	88	Target Neighborhood Hits	190	Shared Neighborhood Hits	44
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

ERC2_HUMAN
θ value	3.0926 (rank : 60)	NC score	0.019164 (rank : 108)
Query Neighborhood Hits	88	Target Neighborhood Hits	1156	Shared Neighborhood Hits	19
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

SI1L3_HUMAN
θ value	3.0926 (rank : 61)	NC score	0.012692 (rank : 115)
Query Neighborhood Hits	88	Target Neighborhood Hits	305	Shared Neighborhood Hits	4
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

TAOK3_HUMAN
θ value	3.0926 (rank : 62)	NC score	0.001530 (rank : 131)
Query Neighborhood Hits	88	Target Neighborhood Hits	1494	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H2K8, Q658N1, Q8IUM4, Q9HC79, Q9NZM9, Q9UHG7	Gene names	TAOK3, DPK, JIK, KDS, MAP3K18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK- inhibitory kinase) (Dendritic cell-derived protein kinase) (Cutaneous T-cell lymphoma tumor antigen HD-CL-09) (CTCL tumor antigen HD-CL-09) (Kinase from chicken homolog A) (hKFC-A).

VPS72_HUMAN
θ value	3.0926 (rank : 63)	NC score	0.038227 (rank : 99)
Query Neighborhood Hits	88	Target Neighborhood Hits	274	Shared Neighborhood Hits	7
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

COG6_MOUSE
θ value	4.03905 (rank : 64)	NC score	0.041721 (rank : 98)
Query Neighborhood Hits	88	Target Neighborhood Hits	79	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R3I3, Q9CTA8	Gene names	Cog6
Domain Architecture
Description	Conserved oligomeric Golgi complex component 6.

PPBI_MOUSE
θ value	4.03905 (rank : 65)	NC score	0.012574 (rank : 116)
Query Neighborhood Hits	88	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	P24822	Gene names	Iap, Akp-3, Akp3
Domain Architecture
Description	Intestinal alkaline phosphatase precursor (EC 3.1.3.1) (IAP).

XRP2_MOUSE
θ value	4.03905 (rank : 66)	NC score	0.022737 (rank : 103)
Query Neighborhood Hits	88	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EPK2, Q8BLN8, Q8BVQ8, Q8BZP9	Gene names	Rp2, Rp2h
Domain Architecture	No domain graphic available
Description	Protein XRP2.

ADAM7_MOUSE
θ value	5.27518 (rank : 67)	NC score	0.004682 (rank : 128)
Query Neighborhood Hits	88	Target Neighborhood Hits	200	Shared Neighborhood Hits	2
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

CYTSA_MOUSE
θ value	5.27518 (rank : 68)	NC score	0.016921 (rank : 110)
Query Neighborhood Hits	88	Target Neighborhood Hits	1104	Shared Neighborhood Hits	19
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

IRK6_HUMAN
θ value	5.27518 (rank : 69)	NC score	0.005745 (rank : 126)
Query Neighborhood Hits	88	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	P48051, Q53WW6	Gene names	KCNJ6, GIRK2, KATP2, KCNJ7
Domain Architecture
Description	G protein-activated inward rectifier potassium channel 2 (GIRK2) (Potassium channel, inwardly rectifying subfamily J member 6) (Inward rectifier K(+) channel Kir3.2) (KATP-2) (BIR1).

KLHL2_HUMAN
θ value	5.27518 (rank : 70)	NC score	0.003164 (rank : 130)
Query Neighborhood Hits	88	Target Neighborhood Hits	191	Shared Neighborhood Hits	2
SwissProt Accessions	O95198, Q8N484, Q8TBH5	Gene names	KLHL2
Domain Architecture
Description	Kelch-like protein 2 (Actin-binding protein Mayven).

PCNT_HUMAN
θ value	5.27518 (rank : 71)	NC score	0.011162 (rank : 118)
Query Neighborhood Hits	88	Target Neighborhood Hits	1551	Shared Neighborhood Hits	20
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

RB6I2_HUMAN
θ value	5.27518 (rank : 72)	NC score	0.018578 (rank : 109)
Query Neighborhood Hits	88	Target Neighborhood Hits	1584	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

SYIM_HUMAN
θ value	5.27518 (rank : 73)	NC score	0.013757 (rank : 113)
Query Neighborhood Hits	88	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NSE4, Q6PI85, Q7L439, Q86WU9, Q96D91	Gene names	IARS2
Domain Architecture	No domain graphic available
Description	Isoleucyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.5) (Isoleucine--tRNA ligase) (IleRS).

TAP1_HUMAN
θ value	5.27518 (rank : 74)	NC score	0.005884 (rank : 125)
Query Neighborhood Hits	88	Target Neighborhood Hits	99	Shared Neighborhood Hits	2
SwissProt Accessions	Q03518, Q16149	Gene names	TAP1, ABCB2, PSF1, RING4, Y3
Domain Architecture
Description	Antigen peptide transporter 1 (APT1) (Peptide transporter TAP1) (ATP- binding cassette sub-family B member 2) (Peptide transporter PSF1) (Peptide supply factor 1) (PSF-1) (Peptide transporter involved in antigen processing 1).

APXL_HUMAN
θ value	6.88961 (rank : 75)	NC score	0.012878 (rank : 114)
Query Neighborhood Hits	88	Target Neighborhood Hits	553	Shared Neighborhood Hits	6
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

BAZ1B_HUMAN
θ value	6.88961 (rank : 76)	NC score	0.010853 (rank : 120)
Query Neighborhood Hits	88	Target Neighborhood Hits	701	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

DDX24_MOUSE
θ value	6.88961 (rank : 77)	NC score	0.130630 (rank : 66)
Query Neighborhood Hits	88	Target Neighborhood Hits	147	Shared Neighborhood Hits	43
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

KIF5C_MOUSE
θ value	6.88961 (rank : 78)	NC score	0.011430 (rank : 117)
Query Neighborhood Hits	88	Target Neighborhood Hits	1040	Shared Neighborhood Hits	17
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

LGP2_HUMAN
θ value	6.88961 (rank : 79)	NC score	0.165371 (rank : 30)
Query Neighborhood Hits	88	Target Neighborhood Hits	94	Shared Neighborhood Hits	39
SwissProt Accessions	Q96C10, Q9HAM6	Gene names	LGP2, D11LGP2E
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2 homolog).

NAL11_HUMAN
θ value	6.88961 (rank : 80)	NC score	0.007470 (rank : 124)
Query Neighborhood Hits	88	Target Neighborhood Hits	66	Shared Neighborhood Hits	2
SwissProt Accessions	P59045, Q53ZZ0, Q8NBF5	Gene names	NALP11, NOD17, PYPAF6
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 11 (PYRIN-containing APAF1-like protein 6) (Nucleotide-binding oligomerization domain protein 17).

SPTB1_MOUSE
θ value	6.88961 (rank : 81)	NC score	0.009565 (rank : 123)
Query Neighborhood Hits	88	Target Neighborhood Hits	543	Shared Neighborhood Hits	15
SwissProt Accessions	P15508	Gene names	Sptb, Spnb-1, Spnb1, Sptb1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

BICD1_HUMAN
θ value	8.99809 (rank : 82)	NC score	0.010559 (rank : 121)
Query Neighborhood Hits	88	Target Neighborhood Hits	844	Shared Neighborhood Hits	15
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

CP39A_MOUSE
θ value	8.99809 (rank : 83)	NC score	0.005658 (rank : 127)
Query Neighborhood Hits	88	Target Neighborhood Hits	116	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JKJ9	Gene names	Cyp39a1
Domain Architecture
Description	Cytochrome P450 39A1 (EC 1.14.13.99) (24-hydroxycholesterol 7-alpha- hydroxylase) (Oxysterol 7-alpha-hydroxylase) (mCYP39A1).

NAF1_MOUSE
θ value	8.99809 (rank : 84)	NC score	0.010216 (rank : 122)
Query Neighborhood Hits	88	Target Neighborhood Hits	852	Shared Neighborhood Hits	16
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

THNSL_HUMAN
θ value	8.99809 (rank : 85)	NC score	0.025677 (rank : 102)
Query Neighborhood Hits	88	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IYQ7, Q5VV21	Gene names	THNSL1
Domain Architecture	No domain graphic available
Description	Threonine synthase-like 1.

TREM1_MOUSE
θ value	8.99809 (rank : 86)	NC score	0.014930 (rank : 112)
Query Neighborhood Hits	88	Target Neighborhood Hits	73	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JKE2, Q3TAL7	Gene names	Trem1
Domain Architecture	No domain graphic available
Description	Triggering receptor expressed on myeloid cells 1 precursor (TREM-1).

TRI49_HUMAN
θ value	8.99809 (rank : 87)	NC score	0.003547 (rank : 129)
Query Neighborhood Hits	88	Target Neighborhood Hits	199	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

WDR85_MOUSE
θ value	8.99809 (rank : 88)	NC score	0.010953 (rank : 119)
Query Neighborhood Hits	88	Target Neighborhood Hits	108	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CYU6, Q5RJV7, Q8BIT9	Gene names	Wdr85
Domain Architecture	No domain graphic available
Description	WD repeat protein 85.

DD19A_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.105525 (rank : 94)
Query Neighborhood Hits	88	Target Neighborhood Hits	107	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DD19A_MOUSE
θ value	θ > 10 (rank : 90)	NC score	0.105601 (rank : 92)
Query Neighborhood Hits	88	Target Neighborhood Hits	105	Shared Neighborhood Hits	40
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DD19B_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.105572 (rank : 93)
Query Neighborhood Hits	88	Target Neighborhood Hits	109	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

DDX10_MOUSE
θ value	θ > 10 (rank : 92)	NC score	0.136205 (rank : 51)
Query Neighborhood Hits	88	Target Neighborhood Hits	233	Shared Neighborhood Hits	44
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX17_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.133969 (rank : 57)
Query Neighborhood Hits	88	Target Neighborhood Hits	104	Shared Neighborhood Hits	44
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

DDX17_MOUSE
θ value	θ > 10 (rank : 94)	NC score	0.133999 (rank : 56)
Query Neighborhood Hits	88	Target Neighborhood Hits	105	Shared Neighborhood Hits	44
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DDX18_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.133906 (rank : 58)
Query Neighborhood Hits	88	Target Neighborhood Hits	124	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

DDX1_HUMAN
θ value	θ > 10 (rank : 96)	NC score	0.107059 (rank : 90)
Query Neighborhood Hits	88	Target Neighborhood Hits	110	Shared Neighborhood Hits	40
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

DDX1_MOUSE
θ value	θ > 10 (rank : 97)	NC score	0.107637 (rank : 88)
Query Neighborhood Hits	88	Target Neighborhood Hits	112	Shared Neighborhood Hits	40
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

DDX20_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.108447 (rank : 87)
Query Neighborhood Hits	88	Target Neighborhood Hits	121	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DDX20_MOUSE
θ value	θ > 10 (rank : 99)	NC score	0.108533 (rank : 86)
Query Neighborhood Hits	88	Target Neighborhood Hits	177	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DDX23_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.131477 (rank : 65)
Query Neighborhood Hits	88	Target Neighborhood Hits	486	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DDX25_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.107260 (rank : 89)
Query Neighborhood Hits	88	Target Neighborhood Hits	93	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UHL0, Q86W81, Q8IYP1	Gene names	DDX25, GRTH
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX25_MOUSE
θ value	θ > 10 (rank : 102)	NC score	0.107036 (rank : 91)
Query Neighborhood Hits	88	Target Neighborhood Hits	98	Shared Neighborhood Hits	39
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX27_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.132275 (rank : 61)
Query Neighborhood Hits	88	Target Neighborhood Hits	197	Shared Neighborhood Hits	43
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX27_MOUSE
θ value	θ > 10 (rank : 104)	NC score	0.132790 (rank : 60)
Query Neighborhood Hits	88	Target Neighborhood Hits	174	Shared Neighborhood Hits	47
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX28_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.123364 (rank : 73)
Query Neighborhood Hits	88	Target Neighborhood Hits	103	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX39_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.117028 (rank : 81)
Query Neighborhood Hits	88	Target Neighborhood Hits	94	Shared Neighborhood Hits	43
SwissProt Accessions	O00148, Q9BVP6, Q9H5W0	Gene names	DDX39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39) (Nuclear RNA helicase URH49).

DDX39_MOUSE
θ value	θ > 10 (rank : 107)	NC score	0.116019 (rank : 82)
Query Neighborhood Hits	88	Target Neighborhood Hits	97	Shared Neighborhood Hits	42
SwissProt Accessions	Q8VDW0, Q3UJV4, Q8C2C2	Gene names	Ddx39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39).

DDX3X_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.126720 (rank : 70)
Query Neighborhood Hits	88	Target Neighborhood Hits	122	Shared Neighborhood Hits	45
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

DDX3X_MOUSE
θ value	θ > 10 (rank : 109)	NC score	0.126784 (rank : 69)
Query Neighborhood Hits	88	Target Neighborhood Hits	117	Shared Neighborhood Hits	44
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

DDX3Y_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.125813 (rank : 72)
Query Neighborhood Hits	88	Target Neighborhood Hits	121	Shared Neighborhood Hits	44
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

DDX3Y_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.129524 (rank : 67)
Query Neighborhood Hits	88	Target Neighborhood Hits	126	Shared Neighborhood Hits	45
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

DDX41_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.134552 (rank : 53)
Query Neighborhood Hits	88	Target Neighborhood Hits	111	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX41_MOUSE
θ value	θ > 10 (rank : 113)	NC score	0.134362 (rank : 55)
Query Neighborhood Hits	88	Target Neighborhood Hits	115	Shared Neighborhood Hits	45
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

DDX48_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.120189 (rank : 74)
Query Neighborhood Hits	88	Target Neighborhood Hits	102	Shared Neighborhood Hits	44
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX48_MOUSE
θ value	θ > 10 (rank : 115)	NC score	0.120097 (rank : 75)
Query Neighborhood Hits	88	Target Neighborhood Hits	102	Shared Neighborhood Hits	44
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

DDX50_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.134390 (rank : 54)
Query Neighborhood Hits	88	Target Neighborhood Hits	132	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX50_MOUSE
θ value	θ > 10 (rank : 117)	NC score	0.133803 (rank : 59)
Query Neighborhood Hits	88	Target Neighborhood Hits	137	Shared Neighborhood Hits	46
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX53_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.127242 (rank : 68)
Query Neighborhood Hits	88	Target Neighborhood Hits	124	Shared Neighborhood Hits	40
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

DDX56_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.115305 (rank : 83)
Query Neighborhood Hits	88	Target Neighborhood Hits	77	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

DDX56_MOUSE
θ value	θ > 10 (rank : 120)	NC score	0.118989 (rank : 80)
Query Neighborhood Hits	88	Target Neighborhood Hits	87	Shared Neighborhood Hits	32
SwissProt Accessions	Q9D0R4	Gene names	Ddx56, D11Ertd619e, Noh61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase).

DDX5_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.131518 (rank : 64)
Query Neighborhood Hits	88	Target Neighborhood Hits	102	Shared Neighborhood Hits	44
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX5_MOUSE
θ value	θ > 10 (rank : 122)	NC score	0.131634 (rank : 63)
Query Neighborhood Hits	88	Target Neighborhood Hits	101	Shared Neighborhood Hits	44
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

DDX6_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.142281 (rank : 46)
Query Neighborhood Hits	88	Target Neighborhood Hits	97	Shared Neighborhood Hits	47
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX6_MOUSE
θ value	θ > 10 (rank : 124)	NC score	0.142149 (rank : 47)
Query Neighborhood Hits	88	Target Neighborhood Hits	98	Shared Neighborhood Hits	47
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

IF4A1_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.119337 (rank : 76)
Query Neighborhood Hits	88	Target Neighborhood Hits	106	Shared Neighborhood Hits	44
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
θ value	θ > 10 (rank : 126)	NC score	0.119337 (rank : 77)
Query Neighborhood Hits	88	Target Neighborhood Hits	106	Shared Neighborhood Hits	44
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A2_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.119308 (rank : 78)
Query Neighborhood Hits	88	Target Neighborhood Hits	102	Shared Neighborhood Hits	44
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
θ value	θ > 10 (rank : 128)	NC score	0.119308 (rank : 79)
Query Neighborhood Hits	88	Target Neighborhood Hits	102	Shared Neighborhood Hits	44
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

PL10_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.126042 (rank : 71)
Query Neighborhood Hits	88	Target Neighborhood Hits	120	Shared Neighborhood Hits	44
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

PTMS_MOUSE
θ value	θ > 10 (rank : 130)	NC score	0.050773 (rank : 96)
Query Neighborhood Hits	88	Target Neighborhood Hits	68	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D0J8	Gene names	Ptms
Domain Architecture	No domain graphic available
Description	Parathymosin.

UAP56_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.113869 (rank : 85)
Query Neighborhood Hits	88	Target Neighborhood Hits	96	Shared Neighborhood Hits	42
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

UAP56_MOUSE
θ value	θ > 10 (rank : 132)	NC score	0.113910 (rank : 84)
Query Neighborhood Hits	88	Target Neighborhood Hits	96	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

Hits sorted by NC score

U520_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	88	Target Neighborhood Hits	88	Shared Neighborhood Hits	88
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

HELC1_HUMAN
NC score	0.952338 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	88	Target Neighborhood Hits	71	Shared Neighborhood Hits	37
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

SKIV2_HUMAN
NC score	0.560851 (rank : 3)	θ value	1.05554e-24 (rank : 3)
Query Neighborhood Hits	88	Target Neighborhood Hits	45	Shared Neighborhood Hits	15
SwissProt Accessions	Q15477, O15005, Q12902, Q15476	Gene names	SKIV2L, DDX13, SKI2W, SKIV2, W
Domain Architecture
Description	Helicase SKI2W (EC 3.6.1.-) (Helicase-like protein) (HLP).

SK2L2_MOUSE
NC score	0.531526 (rank : 4)	θ value	3.51386e-20 (rank : 4)
Query Neighborhood Hits	88	Target Neighborhood Hits	45	Shared Neighborhood Hits	15
SwissProt Accessions	Q9CZU3	Gene names	Skiv2l2
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

SK2L2_HUMAN
NC score	0.530507 (rank : 5)	θ value	7.82807e-20 (rank : 5)
Query Neighborhood Hits	88	Target Neighborhood Hits	36	Shared Neighborhood Hits	15
SwissProt Accessions	P42285, Q8TAG2	Gene names	SKIV2L2, KIAA0052
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

SEC63_HUMAN
NC score	0.245601 (rank : 6)	θ value	3.18553e-13 (rank : 6)
Query Neighborhood Hits	88	Target Neighborhood Hits	586	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

SEC63_MOUSE
NC score	0.244476 (rank : 7)	θ value	7.09661e-13 (rank : 7)
Query Neighborhood Hits	88	Target Neighborhood Hits	601	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

RECQ4_MOUSE
NC score	0.208678 (rank : 8)	θ value	0.0113563 (rank : 22)
Query Neighborhood Hits	88	Target Neighborhood Hits	206	Shared Neighborhood Hits	45
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

RECQ5_HUMAN
NC score	0.206708 (rank : 9)	θ value	0.000158464 (rank : 11)
Query Neighborhood Hits	88	Target Neighborhood Hits	390	Shared Neighborhood Hits	39
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

DICER_MOUSE
NC score	0.206236 (rank : 10)	θ value	0.00102713 (rank : 14)
Query Neighborhood Hits	88	Target Neighborhood Hits	140	Shared Neighborhood Hits	43
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

RECQ4_HUMAN
NC score	0.204930 (rank : 11)	θ value	0.47712 (rank : 42)
Query Neighborhood Hits	88	Target Neighborhood Hits	177	Shared Neighborhood Hits	47
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

FANCM_MOUSE
NC score	0.200565 (rank : 12)	θ value	0.00869519 (rank : 18)
Query Neighborhood Hits	88	Target Neighborhood Hits	177	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

DDX58_MOUSE
NC score	0.199517 (rank : 13)	θ value	0.0148317 (rank : 23)
Query Neighborhood Hits	88	Target Neighborhood Hits	99	Shared Neighborhood Hits	34
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

WRN_HUMAN
NC score	0.198409 (rank : 14)	θ value	0.0148317 (rank : 24)
Query Neighborhood Hits	88	Target Neighborhood Hits	132	Shared Neighborhood Hits	45
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

DDX58_HUMAN
NC score	0.195034 (rank : 15)	θ value	0.0113563 (rank : 20)
Query Neighborhood Hits	88	Target Neighborhood Hits	105	Shared Neighborhood Hits	35
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

FANCM_HUMAN
NC score	0.194200 (rank : 16)	θ value	0.0431538 (rank : 29)
Query Neighborhood Hits	88	Target Neighborhood Hits	210	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

DICER_HUMAN
NC score	0.193987 (rank : 17)	θ value	0.0113563 (rank : 21)
Query Neighborhood Hits	88	Target Neighborhood Hits	126	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

RECQ1_HUMAN
NC score	0.189869 (rank : 18)	θ value	0.0961366 (rank : 33)
Query Neighborhood Hits	88	Target Neighborhood Hits	100	Shared Neighborhood Hits	43
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

DDX52_MOUSE
NC score	0.189152 (rank : 19)	θ value	0.000158464 (rank : 10)
Query Neighborhood Hits	88	Target Neighborhood Hits	101	Shared Neighborhood Hits	48
SwissProt Accessions	Q8K301, Q8BV29	Gene names	Ddx52, Rok1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX52_HUMAN
NC score	0.187228 (rank : 20)	θ value	0.00175202 (rank : 15)
Query Neighborhood Hits	88	Target Neighborhood Hits	107	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

IFIH1_MOUSE
NC score	0.183148 (rank : 21)	θ value	0.0193708 (rank : 26)
Query Neighborhood Hits	88	Target Neighborhood Hits	126	Shared Neighborhood Hits	43
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

DDX51_MOUSE
NC score	0.180040 (rank : 22)	θ value	0.00035302 (rank : 12)
Query Neighborhood Hits	88	Target Neighborhood Hits	130	Shared Neighborhood Hits	47
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

LGP2_MOUSE
NC score	0.179113 (rank : 23)	θ value	0.163984 (rank : 35)
Query Neighborhood Hits	88	Target Neighborhood Hits	86	Shared Neighborhood Hits	37
SwissProt Accessions	Q99J87, Q9D1X4	Gene names	Lgp2, D11lgp2e
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2).

DDX46_HUMAN
NC score	0.178506 (rank : 24)	θ value	0.000121331 (rank : 8)
Query Neighborhood Hits	88	Target Neighborhood Hits	357	Shared Neighborhood Hits	53
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX46_MOUSE
NC score	0.178376 (rank : 25)	θ value	0.000121331 (rank : 9)
Query Neighborhood Hits	88	Target Neighborhood Hits	358	Shared Neighborhood Hits	53
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

RECQ1_MOUSE
NC score	0.177212 (rank : 26)	θ value	0.21417 (rank : 37)
Query Neighborhood Hits	88	Target Neighborhood Hits	95	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

WRN_MOUSE
NC score	0.175935 (rank : 27)	θ value	0.279714 (rank : 40)
Query Neighborhood Hits	88	Target Neighborhood Hits	295	Shared Neighborhood Hits	45
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

DDX51_HUMAN
NC score	0.175661 (rank : 28)	θ value	0.0961366 (rank : 32)
Query Neighborhood Hits	88	Target Neighborhood Hits	332	Shared Neighborhood Hits	48
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

IFIH1_HUMAN
NC score	0.170753 (rank : 29)	θ value	0.125558 (rank : 34)
Query Neighborhood Hits	88	Target Neighborhood Hits	96	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

LGP2_HUMAN
NC score	0.165371 (rank : 30)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	88	Target Neighborhood Hits	94	Shared Neighborhood Hits	39
SwissProt Accessions	Q96C10, Q9HAM6	Gene names	LGP2, D11LGP2E
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2 homolog).

DDX31_HUMAN
NC score	0.163033 (rank : 31)	θ value	0.0736092 (rank : 31)
Query Neighborhood Hits	88	Target Neighborhood Hits	132	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

DDX55_HUMAN
NC score	0.159881 (rank : 32)	θ value	0.000602161 (rank : 13)
Query Neighborhood Hits	88	Target Neighborhood Hits	122	Shared Neighborhood Hits	43
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX4_HUMAN
NC score	0.159273 (rank : 33)	θ value	0.0193708 (rank : 25)
Query Neighborhood Hits	88	Target Neighborhood Hits	123	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

DDX55_MOUSE
NC score	0.157942 (rank : 34)	θ value	0.00175202 (rank : 16)
Query Neighborhood Hits	88	Target Neighborhood Hits	111	Shared Neighborhood Hits	44
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX4_MOUSE
NC score	0.157596 (rank : 35)	θ value	0.0431538 (rank : 28)
Query Neighborhood Hits	88	Target Neighborhood Hits	100	Shared Neighborhood Hits	46
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

DDX43_HUMAN
NC score	0.157212 (rank : 36)	θ value	0.00509761 (rank : 17)
Query Neighborhood Hits	88	Target Neighborhood Hits	120	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

BLM_HUMAN
NC score	0.155505 (rank : 37)	θ value	0.0252991 (rank : 27)
Query Neighborhood Hits	88	Target Neighborhood Hits	148	Shared Neighborhood Hits	36
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

DDX10_HUMAN
NC score	0.153939 (rank : 38)	θ value	0.0113563 (rank : 19)
Query Neighborhood Hits	88	Target Neighborhood Hits	210	Shared Neighborhood Hits	44
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX49_HUMAN
NC score	0.149134 (rank : 39)	θ value	0.47712 (rank : 41)
Query Neighborhood Hits	88	Target Neighborhood Hits	223	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX49_MOUSE
NC score	0.148771 (rank : 40)	θ value	0.21417 (rank : 36)
Query Neighborhood Hits	88	Target Neighborhood Hits	119	Shared Neighborhood Hits	48
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX18_MOUSE
NC score	0.145476 (rank : 41)	θ value	0.0563607 (rank : 30)
Query Neighborhood Hits	88	Target Neighborhood Hits	115	Shared Neighborhood Hits	39
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

DDX54_MOUSE
NC score	0.144441 (rank : 42)	θ value	1.06291 (rank : 49)
Query Neighborhood Hits	88	Target Neighborhood Hits	124	Shared Neighborhood Hits	46
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

BLM_MOUSE
NC score	0.144157 (rank : 43)	θ value	3.0926 (rank : 56)
Query Neighborhood Hits	88	Target Neighborhood Hits	108	Shared Neighborhood Hits	35
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

DDX54_HUMAN
NC score	0.143968 (rank : 44)	θ value	1.81305 (rank : 53)
Query Neighborhood Hits	88	Target Neighborhood Hits	170	Shared Neighborhood Hits	46
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

DDX47_HUMAN
NC score	0.142516 (rank : 45)	θ value	0.62314 (rank : 43)
Query Neighborhood Hits	88	Target Neighborhood Hits	97	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX6_HUMAN
NC score	0.142281 (rank : 46)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	88	Target Neighborhood Hits	97	Shared Neighborhood Hits	47
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX6_MOUSE
NC score	0.142149 (rank : 47)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	88	Target Neighborhood Hits	98	Shared Neighborhood Hits	47
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

DDX47_MOUSE
NC score	0.142135 (rank : 48)	θ value	0.813845 (rank : 46)
Query Neighborhood Hits	88	Target Neighborhood Hits	97	Shared Neighborhood Hits	44
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX21_HUMAN
NC score	0.141538 (rank : 49)	θ value	3.0926 (rank : 58)
Query Neighborhood Hits	88	Target Neighborhood Hits	308	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX28_MOUSE
NC score	0.139341 (rank : 50)	θ value	0.813845 (rank : 45)
Query Neighborhood Hits	88	Target Neighborhood Hits	112	Shared Neighborhood Hits	46
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX10_MOUSE
NC score	0.136205 (rank : 51)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	88	Target Neighborhood Hits	233	Shared Neighborhood Hits	44
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX21_MOUSE
NC score	0.134863 (rank : 52)	θ value	1.38821 (rank : 50)
Query Neighborhood Hits	88	Target Neighborhood Hits	350	Shared Neighborhood Hits	46
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX41_HUMAN
NC score	0.134552 (rank : 53)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	88	Target Neighborhood Hits	111	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX50_HUMAN
NC score	0.134390 (rank : 54)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	88	Target Neighborhood Hits	132	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX41_MOUSE
NC score	0.134362 (rank : 55)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	88	Target Neighborhood Hits	115	Shared Neighborhood Hits	45
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

DDX17_MOUSE
NC score	0.133999 (rank : 56)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	88	Target Neighborhood Hits	105	Shared Neighborhood Hits	44
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DDX17_HUMAN
NC score	0.133969 (rank : 57)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	88	Target Neighborhood Hits	104	Shared Neighborhood Hits	44
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

DDX18_HUMAN
NC score	0.133906 (rank : 58)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	88	Target Neighborhood Hits	124	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

DDX50_MOUSE
NC score	0.133803 (rank : 59)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	88	Target Neighborhood Hits	137	Shared Neighborhood Hits	46
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX27_MOUSE
NC score	0.132790 (rank : 60)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	88	Target Neighborhood Hits	174	Shared Neighborhood Hits	47
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX27_HUMAN
NC score	0.132275 (rank : 61)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	88	Target Neighborhood Hits	197	Shared Neighborhood Hits	43
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX24_HUMAN
NC score	0.131961 (rank : 62)	θ value	3.0926 (rank : 59)
Query Neighborhood Hits	88	Target Neighborhood Hits	190	Shared Neighborhood Hits	44
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX5_MOUSE
NC score	0.131634 (rank : 63)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	88	Target Neighborhood Hits	101	Shared Neighborhood Hits	44
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

DDX5_HUMAN
NC score	0.131518 (rank : 64)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	88	Target Neighborhood Hits	102	Shared Neighborhood Hits	44
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX23_HUMAN
NC score	0.131477 (rank : 65)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	88	Target Neighborhood Hits	486	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DDX24_MOUSE
NC score	0.130630 (rank : 66)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	88	Target Neighborhood Hits	147	Shared Neighborhood Hits	43
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX3Y_MOUSE
NC score	0.129524 (rank : 67)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	88	Target Neighborhood Hits	126	Shared Neighborhood Hits	45
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

DDX53_HUMAN
NC score	0.127242 (rank : 68)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	88	Target Neighborhood Hits	124	Shared Neighborhood Hits	40
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

DDX3X_MOUSE
NC score	0.126784 (rank : 69)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	88	Target Neighborhood Hits	117	Shared Neighborhood Hits	44
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

DDX3X_HUMAN
NC score	0.126720 (rank : 70)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	88	Target Neighborhood Hits	122	Shared Neighborhood Hits	45
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

PL10_MOUSE
NC score	0.126042 (rank : 71)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	88	Target Neighborhood Hits	120	Shared Neighborhood Hits	44
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

DDX3Y_HUMAN
NC score	0.125813 (rank : 72)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	88	Target Neighborhood Hits	121	Shared Neighborhood Hits	44
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

DDX28_HUMAN
NC score	0.123364 (rank : 73)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	88	Target Neighborhood Hits	103	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX48_HUMAN
NC score	0.120189 (rank : 74)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	88	Target Neighborhood Hits	102	Shared Neighborhood Hits	44
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX48_MOUSE
NC score	0.120097 (rank : 75)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	88	Target Neighborhood Hits	102	Shared Neighborhood Hits	44
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

IF4A1_HUMAN
NC score	0.119337 (rank : 76)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	88	Target Neighborhood Hits	106	Shared Neighborhood Hits	44
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
NC score	0.119337 (rank : 77)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	88	Target Neighborhood Hits	106	Shared Neighborhood Hits	44
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A2_HUMAN
NC score	0.119308 (rank : 78)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	88	Target Neighborhood Hits	102	Shared Neighborhood Hits	44
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
NC score	0.119308 (rank : 79)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	88	Target Neighborhood Hits	102	Shared Neighborhood Hits	44
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

DDX56_MOUSE
NC score	0.118989 (rank : 80)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	88	Target Neighborhood Hits	87	Shared Neighborhood Hits	32
SwissProt Accessions	Q9D0R4	Gene names	Ddx56, D11Ertd619e, Noh61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase).

DDX39_HUMAN
NC score	0.117028 (rank : 81)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	88	Target Neighborhood Hits	94	Shared Neighborhood Hits	43
SwissProt Accessions	O00148, Q9BVP6, Q9H5W0	Gene names	DDX39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39) (Nuclear RNA helicase URH49).

DDX39_MOUSE
NC score	0.116019 (rank : 82)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	88	Target Neighborhood Hits	97	Shared Neighborhood Hits	42
SwissProt Accessions	Q8VDW0, Q3UJV4, Q8C2C2	Gene names	Ddx39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39).

DDX56_HUMAN
NC score	0.115305 (rank : 83)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	88	Target Neighborhood Hits	77	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

UAP56_MOUSE
NC score	0.113910 (rank : 84)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	88	Target Neighborhood Hits	96	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

UAP56_HUMAN
NC score	0.113869 (rank : 85)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	88	Target Neighborhood Hits	96	Shared Neighborhood Hits	42
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

DDX20_MOUSE
NC score	0.108533 (rank : 86)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	88	Target Neighborhood Hits	177	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DDX20_HUMAN
NC score	0.108447 (rank : 87)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	88	Target Neighborhood Hits	121	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DDX1_MOUSE
NC score	0.107637 (rank : 88)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	88	Target Neighborhood Hits	112	Shared Neighborhood Hits	40
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

DDX25_HUMAN
NC score	0.107260 (rank : 89)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	88	Target Neighborhood Hits	93	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UHL0, Q86W81, Q8IYP1	Gene names	DDX25, GRTH
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX1_HUMAN
NC score	0.107059 (rank : 90)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	88	Target Neighborhood Hits	110	Shared Neighborhood Hits	40
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

DDX25_MOUSE
NC score	0.107036 (rank : 91)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	88	Target Neighborhood Hits	98	Shared Neighborhood Hits	39
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DD19A_MOUSE
NC score	0.105601 (rank : 92)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	88	Target Neighborhood Hits	105	Shared Neighborhood Hits	40
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DD19B_HUMAN
NC score	0.105572 (rank : 93)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	88	Target Neighborhood Hits	109	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

DD19A_HUMAN
NC score	0.105525 (rank : 94)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	88	Target Neighborhood Hits	107	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

COG6_HUMAN
NC score	0.058623 (rank : 95)	θ value	0.279714 (rank : 38)
Query Neighborhood Hits	88	Target Neighborhood Hits	118	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y2V7, Q5T0U1, Q9ULT5	Gene names	COG6, KIAA1134
Domain Architecture
Description	Conserved oligomeric Golgi complex component 6.

PTMS_MOUSE
NC score	0.050773 (rank : 96)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	88	Target Neighborhood Hits	68	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D0J8	Gene names	Ptms
Domain Architecture	No domain graphic available
Description	Parathymosin.

VPS72_MOUSE
NC score	0.044483 (rank : 97)	θ value	0.813845 (rank : 47)
Query Neighborhood Hits	88	Target Neighborhood Hits	286	Shared Neighborhood Hits	6
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

COG6_MOUSE
NC score	0.041721 (rank : 98)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	88	Target Neighborhood Hits	79	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R3I3, Q9CTA8	Gene names	Cog6
Domain Architecture
Description	Conserved oligomeric Golgi complex component 6.

VPS72_HUMAN
NC score	0.038227 (rank : 99)	θ value	3.0926 (rank : 63)
Query Neighborhood Hits	88	Target Neighborhood Hits	274	Shared Neighborhood Hits	7
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

THNSL_MOUSE
NC score	0.036823 (rank : 100)	θ value	1.38821 (rank : 52)
Query Neighborhood Hits	88	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BH55	Gene names	Thnsl1
Domain Architecture	No domain graphic available
Description	Threonine synthase-like 1.

LEO1_MOUSE
NC score	0.029873 (rank : 101)	θ value	1.38821 (rank : 51)
Query Neighborhood Hits	88	Target Neighborhood Hits	946	Shared Neighborhood Hits	14
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

THNSL_HUMAN
NC score	0.025677 (rank : 102)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	88	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IYQ7, Q5VV21	Gene names	THNSL1
Domain Architecture	No domain graphic available
Description	Threonine synthase-like 1.

XRP2_MOUSE
NC score	0.022737 (rank : 103)	θ value	4.03905 (rank : 66)
Query Neighborhood Hits	88	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EPK2, Q8BLN8, Q8BVQ8, Q8BZP9	Gene names	Rp2, Rp2h
Domain Architecture	No domain graphic available
Description	Protein XRP2.

GOGB1_HUMAN
NC score	0.020697 (rank : 104)	θ value	0.279714 (rank : 39)
Query Neighborhood Hits	88	Target Neighborhood Hits	2297	Shared Neighborhood Hits	28
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

CYTSA_HUMAN
NC score	0.020224 (rank : 105)	θ value	1.06291 (rank : 48)
Query Neighborhood Hits	88	Target Neighborhood Hits	1138	Shared Neighborhood Hits	20
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

ERC2_MOUSE
NC score	0.020181 (rank : 106)	θ value	2.36792 (rank : 54)
Query Neighborhood Hits	88	Target Neighborhood Hits	1166	Shared Neighborhood Hits	20
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

RB6I2_MOUSE
NC score	0.019662 (rank : 107)	θ value	2.36792 (rank : 55)
Query Neighborhood Hits	88	Target Neighborhood Hits	1433	Shared Neighborhood Hits	24
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

ERC2_HUMAN
NC score	0.019164 (rank : 108)	θ value	3.0926 (rank : 60)
Query Neighborhood Hits	88	Target Neighborhood Hits	1156	Shared Neighborhood Hits	19
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

RB6I2_HUMAN
NC score	0.018578 (rank : 109)	θ value	5.27518 (rank : 72)
Query Neighborhood Hits	88	Target Neighborhood Hits	1584	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

CYTSA_MOUSE
NC score	0.016921 (rank : 110)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	88	Target Neighborhood Hits	1104	Shared Neighborhood Hits	19
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

KIF5C_HUMAN
NC score	0.015552 (rank : 111)	θ value	0.62314 (rank : 44)
Query Neighborhood Hits	88	Target Neighborhood Hits	974	Shared Neighborhood Hits	17
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

TREM1_MOUSE
NC score	0.014930 (rank : 112)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	88	Target Neighborhood Hits	73	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JKE2, Q3TAL7	Gene names	Trem1
Domain Architecture	No domain graphic available
Description	Triggering receptor expressed on myeloid cells 1 precursor (TREM-1).

SYIM_HUMAN
NC score	0.013757 (rank : 113)	θ value	5.27518 (rank : 73)
Query Neighborhood Hits	88	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NSE4, Q6PI85, Q7L439, Q86WU9, Q96D91	Gene names	IARS2
Domain Architecture	No domain graphic available
Description	Isoleucyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.5) (Isoleucine--tRNA ligase) (IleRS).

APXL_HUMAN
NC score	0.012878 (rank : 114)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	88	Target Neighborhood Hits	553	Shared Neighborhood Hits	6
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

SI1L3_HUMAN
NC score	0.012692 (rank : 115)	θ value	3.0926 (rank : 61)
Query Neighborhood Hits	88	Target Neighborhood Hits	305	Shared Neighborhood Hits	4
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

PPBI_MOUSE
NC score	0.012574 (rank : 116)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	88	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	P24822	Gene names	Iap, Akp-3, Akp3
Domain Architecture
Description	Intestinal alkaline phosphatase precursor (EC 3.1.3.1) (IAP).

KIF5C_MOUSE
NC score	0.011430 (rank : 117)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	88	Target Neighborhood Hits	1040	Shared Neighborhood Hits	17
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

PCNT_HUMAN
NC score	0.011162 (rank : 118)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	88	Target Neighborhood Hits	1551	Shared Neighborhood Hits	20
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

WDR85_MOUSE
NC score	0.010953 (rank : 119)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	88	Target Neighborhood Hits	108	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CYU6, Q5RJV7, Q8BIT9	Gene names	Wdr85
Domain Architecture	No domain graphic available
Description	WD repeat protein 85.

BAZ1B_HUMAN
NC score	0.010853 (rank : 120)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	88	Target Neighborhood Hits	701	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

BICD1_HUMAN
NC score	0.010559 (rank : 121)	θ value	8.99809 (rank : 82)
Query Neighborhood Hits	88	Target Neighborhood Hits	844	Shared Neighborhood Hits	15
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

NAF1_MOUSE
NC score	0.010216 (rank : 122)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	88	Target Neighborhood Hits	852	Shared Neighborhood Hits	16
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

SPTB1_MOUSE
NC score	0.009565 (rank : 123)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	88	Target Neighborhood Hits	543	Shared Neighborhood Hits	15
SwissProt Accessions	P15508	Gene names	Sptb, Spnb-1, Spnb1, Sptb1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

NAL11_HUMAN
NC score	0.007470 (rank : 124)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	88	Target Neighborhood Hits	66	Shared Neighborhood Hits	2
SwissProt Accessions	P59045, Q53ZZ0, Q8NBF5	Gene names	NALP11, NOD17, PYPAF6
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 11 (PYRIN-containing APAF1-like protein 6) (Nucleotide-binding oligomerization domain protein 17).

TAP1_HUMAN
NC score	0.005884 (rank : 125)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	88	Target Neighborhood Hits	99	Shared Neighborhood Hits	2
SwissProt Accessions	Q03518, Q16149	Gene names	TAP1, ABCB2, PSF1, RING4, Y3
Domain Architecture
Description	Antigen peptide transporter 1 (APT1) (Peptide transporter TAP1) (ATP- binding cassette sub-family B member 2) (Peptide transporter PSF1) (Peptide supply factor 1) (PSF-1) (Peptide transporter involved in antigen processing 1).

IRK6_HUMAN
NC score	0.005745 (rank : 126)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	88	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	P48051, Q53WW6	Gene names	KCNJ6, GIRK2, KATP2, KCNJ7
Domain Architecture
Description	G protein-activated inward rectifier potassium channel 2 (GIRK2) (Potassium channel, inwardly rectifying subfamily J member 6) (Inward rectifier K(+) channel Kir3.2) (KATP-2) (BIR1).

CP39A_MOUSE
NC score	0.005658 (rank : 127)	θ value	8.99809 (rank : 83)
Query Neighborhood Hits	88	Target Neighborhood Hits	116	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JKJ9	Gene names	Cyp39a1
Domain Architecture
Description	Cytochrome P450 39A1 (EC 1.14.13.99) (24-hydroxycholesterol 7-alpha- hydroxylase) (Oxysterol 7-alpha-hydroxylase) (mCYP39A1).

ADAM7_MOUSE
NC score	0.004682 (rank : 128)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	88	Target Neighborhood Hits	200	Shared Neighborhood Hits	2
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

TRI49_HUMAN
NC score	0.003547 (rank : 129)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	88	Target Neighborhood Hits	199	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

KLHL2_HUMAN
NC score	0.003164 (rank : 130)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	88	Target Neighborhood Hits	191	Shared Neighborhood Hits	2
SwissProt Accessions	O95198, Q8N484, Q8TBH5	Gene names	KLHL2
Domain Architecture
Description	Kelch-like protein 2 (Actin-binding protein Mayven).

TAOK3_HUMAN
NC score	0.001530 (rank : 131)	θ value	3.0926 (rank : 62)
Query Neighborhood Hits	88	Target Neighborhood Hits	1494	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H2K8, Q658N1, Q8IUM4, Q9HC79, Q9NZM9, Q9UHG7	Gene names	TAOK3, DPK, JIK, KDS, MAP3K18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK- inhibitory kinase) (Dendritic cell-derived protein kinase) (Cutaneous T-cell lymphoma tumor antigen HD-CL-09) (CTCL tumor antigen HD-CL-09) (Kinase from chicken homolog A) (hKFC-A).

CCR4_MOUSE
NC score	0.001222 (rank : 132)	θ value	3.0926 (rank : 57)
Query Neighborhood Hits	88	Target Neighborhood Hits	728	Shared Neighborhood Hits	2
SwissProt Accessions	P51680	Gene names	Ccr4, Cmkbr4
Domain Architecture
Description	C-C chemokine receptor type 4 (C-C CKR-4) (CC-CKR-4) (CCR-4) (CCR4).