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Network neighborhood for query Sequence : SK2L2_MOUSE

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SK2L2_MOUSE
SwissProt Accessions	Q9CZU3	Gene names	Skiv2l2
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SK2L2_HUMAN
θ value	0 (rank : 1)	NC score	0.999051 (rank : 2)
Query Neighborhood Hits	45	Target Neighborhood Hits	36	Shared Neighborhood Hits	35
SwissProt Accessions	P42285, Q8TAG2	Gene names	SKIV2L2, KIAA0052
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

SK2L2_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	45	Target Neighborhood Hits	45	Shared Neighborhood Hits	45
SwissProt Accessions	Q9CZU3	Gene names	Skiv2l2
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

SKIV2_HUMAN
θ value	3.26429e-159 (rank : 3)	NC score	0.936298 (rank : 3)
Query Neighborhood Hits	45	Target Neighborhood Hits	45	Shared Neighborhood Hits	16
SwissProt Accessions	Q15477, O15005, Q12902, Q15476	Gene names	SKIV2L, DDX13, SKI2W, SKIV2, W
Domain Architecture
Description	Helicase SKI2W (EC 3.6.1.-) (Helicase-like protein) (HLP).

HELC1_HUMAN
θ value	8.08199e-25 (rank : 4)	NC score	0.554084 (rank : 4)
Query Neighborhood Hits	45	Target Neighborhood Hits	71	Shared Neighborhood Hits	15
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

U520_HUMAN
θ value	3.51386e-20 (rank : 5)	NC score	0.531526 (rank : 5)
Query Neighborhood Hits	45	Target Neighborhood Hits	88	Shared Neighborhood Hits	15
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

RECQ1_HUMAN
θ value	0.00665767 (rank : 6)	NC score	0.133889 (rank : 6)
Query Neighborhood Hits	45	Target Neighborhood Hits	100	Shared Neighborhood Hits	16
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

DDX54_HUMAN
θ value	0.0113563 (rank : 7)	NC score	0.066072 (rank : 13)
Query Neighborhood Hits	45	Target Neighborhood Hits	170	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

DDX54_MOUSE
θ value	0.0193708 (rank : 8)	NC score	0.063154 (rank : 14)
Query Neighborhood Hits	45	Target Neighborhood Hits	124	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

DHX36_MOUSE
θ value	0.0252991 (rank : 9)	NC score	0.051944 (rank : 17)
Query Neighborhood Hits	45	Target Neighborhood Hits	114	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VHK9, Q6ZPP7, Q9CSE8	Gene names	Dhx36, Ddx36, Kiaa1488, Mlel1
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

RECQ1_MOUSE
θ value	0.0736092 (rank : 10)	NC score	0.115892 (rank : 7)
Query Neighborhood Hits	45	Target Neighborhood Hits	95	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

INT1_MOUSE
θ value	0.0961366 (rank : 11)	NC score	0.076283 (rank : 12)
Query Neighborhood Hits	45	Target Neighborhood Hits	44	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P4S8, Q80UQ7, Q91Z01, Q9CTF7	Gene names	Ints1
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 1 (Int1).

DHX36_HUMAN
θ value	0.21417 (rank : 12)	NC score	0.051711 (rank : 18)
Query Neighborhood Hits	45	Target Neighborhood Hits	63	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H2U1, Q70JU3, Q8IYE5, Q9P240	Gene names	DHX36, DDX36, KIAA1488, MLEL1, RHAU
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

MYO5B_HUMAN
θ value	0.279714 (rank : 13)	NC score	0.034924 (rank : 24)
Query Neighborhood Hits	45	Target Neighborhood Hits	911	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

RECQ4_HUMAN
θ value	0.365318 (rank : 14)	NC score	0.101174 (rank : 9)
Query Neighborhood Hits	45	Target Neighborhood Hits	177	Shared Neighborhood Hits	18
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

WRN_HUMAN
θ value	0.47712 (rank : 15)	NC score	0.104504 (rank : 8)
Query Neighborhood Hits	45	Target Neighborhood Hits	132	Shared Neighborhood Hits	19
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

K0841_HUMAN
θ value	1.06291 (rank : 16)	NC score	0.045369 (rank : 22)
Query Neighborhood Hits	45	Target Neighborhood Hits	119	Shared Neighborhood Hits	9
SwissProt Accessions	O94927, Q6P2P7, Q7L3D5, Q96CT8	Gene names	KIAA0841
Domain Architecture	No domain graphic available
Description	Protein KIAA0841.

MYO5A_HUMAN
θ value	1.06291 (rank : 17)	NC score	0.030852 (rank : 29)
Query Neighborhood Hits	45	Target Neighborhood Hits	1092	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

MYO5A_MOUSE
θ value	1.06291 (rank : 18)	NC score	0.030955 (rank : 28)
Query Neighborhood Hits	45	Target Neighborhood Hits	1117	Shared Neighborhood Hits	17
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

RECQ4_MOUSE
θ value	1.38821 (rank : 19)	NC score	0.095831 (rank : 10)
Query Neighborhood Hits	45	Target Neighborhood Hits	206	Shared Neighborhood Hits	16
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

MY18B_HUMAN
θ value	1.81305 (rank : 20)	NC score	0.022752 (rank : 32)
Query Neighborhood Hits	45	Target Neighborhood Hits	1299	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

CV106_HUMAN
θ value	2.36792 (rank : 21)	NC score	0.047896 (rank : 20)
Query Neighborhood Hits	45	Target Neighborhood Hits	125	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P0N0, Q86V14, Q96PY4, Q9NUR5, Q9Y4X9	Gene names	C14orf106, KIAA1903
Domain Architecture	No domain graphic available
Description	Protein C14orf106 (P243).

JAD1D_MOUSE
θ value	3.0926 (rank : 22)	NC score	0.013376 (rank : 43)
Query Neighborhood Hits	45	Target Neighborhood Hits	228	Shared Neighborhood Hits	5
SwissProt Accessions	Q62240, Q9QVR9, Q9R040	Gene names	Smcy, Hya, Jarid1d
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

MYO5C_HUMAN
θ value	3.0926 (rank : 23)	NC score	0.026608 (rank : 30)
Query Neighborhood Hits	45	Target Neighborhood Hits	1206	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

PGES2_HUMAN
θ value	3.0926 (rank : 24)	NC score	0.049779 (rank : 19)
Query Neighborhood Hits	45	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H7Z7, Q53EW9, Q5SYV6, Q96GI0, Q96GL2	Gene names	PTGES2, PGES2
Domain Architecture	No domain graphic available
Description	Prostaglandin E synthase 2 (EC 5.3.99.3) (Microsomal prostaglandin E synthase 2) (mPGES-2) [Contains: Prostaglandin E synthase 2 truncated form].

TLR11_MOUSE
θ value	3.0926 (rank : 25)	NC score	0.012376 (rank : 46)
Query Neighborhood Hits	45	Target Neighborhood Hits	293	Shared Neighborhood Hits	3
SwissProt Accessions	Q6R5P0	Gene names	Tlr11
Domain Architecture	No domain graphic available
Description	Toll-like receptor 11 precursor.

MYH4_MOUSE
θ value	4.03905 (rank : 26)	NC score	0.018364 (rank : 38)
Query Neighborhood Hits	45	Target Neighborhood Hits	1476	Shared Neighborhood Hits	17
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

MYH6_HUMAN
θ value	4.03905 (rank : 27)	NC score	0.018386 (rank : 37)
Query Neighborhood Hits	45	Target Neighborhood Hits	1426	Shared Neighborhood Hits	18
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

PGES2_MOUSE
θ value	4.03905 (rank : 28)	NC score	0.046343 (rank : 21)
Query Neighborhood Hits	45	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BWM0, Q99J30	Gene names	Ptges2, Gbf1, Pges2
Domain Architecture	No domain graphic available
Description	Prostaglandin E synthase 2 (EC 5.3.99.3) (Microsomal prostaglandin E synthase 2) (mPGES-2) (GATE-binding factor 1) (GBF-1) [Contains: Prostaglandin E synthase 2 truncated form].

RAD50_HUMAN
θ value	4.03905 (rank : 29)	NC score	0.014756 (rank : 41)
Query Neighborhood Hits	45	Target Neighborhood Hits	1317	Shared Neighborhood Hits	18
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

CR034_MOUSE
θ value	5.27518 (rank : 30)	NC score	0.020610 (rank : 35)
Query Neighborhood Hits	45	Target Neighborhood Hits	643	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CDV0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34 homolog.

DDX52_HUMAN
θ value	5.27518 (rank : 31)	NC score	0.036729 (rank : 23)
Query Neighborhood Hits	45	Target Neighborhood Hits	107	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DNJC3_HUMAN
θ value	5.27518 (rank : 32)	NC score	0.021306 (rank : 33)
Query Neighborhood Hits	45	Target Neighborhood Hits	223	Shared Neighborhood Hits	10
SwissProt Accessions	Q13217, Q86WT9, Q8N4N2	Gene names	DNAJC3, P58IPK, PRKRI
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 3 (Interferon-induced, double-stranded RNA-activated protein kinase inhibitor) (Protein kinase inhibitor p58) (Protein kinase inhibitor of 58 kDa).

DNJC3_MOUSE
θ value	5.27518 (rank : 33)	NC score	0.021010 (rank : 34)
Query Neighborhood Hits	45	Target Neighborhood Hits	230	Shared Neighborhood Hits	8
SwissProt Accessions	Q91YW3, Q60873	Gene names	Dnajc3, P58ipk
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 3 (Interferon-induced, double-stranded RNA-activated protein kinase inhibitor) (Protein kinase inhibitor p58) (Protein kinase inhibitor of 58 kDa).

CCD41_MOUSE
θ value	6.88961 (rank : 34)	NC score	0.013097 (rank : 44)
Query Neighborhood Hits	45	Target Neighborhood Hits	1399	Shared Neighborhood Hits	22
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

DHX8_HUMAN
θ value	6.88961 (rank : 35)	NC score	0.023028 (rank : 31)
Query Neighborhood Hits	45	Target Neighborhood Hits	86	Shared Neighborhood Hits	7
SwissProt Accessions	Q14562	Gene names	DHX8, DDX8
Domain Architecture
Description	ATP-dependent RNA helicase DHX8 (EC 3.6.1.-) (DEAH box protein 8) (RNA helicase HRH1).

IF39_HUMAN
θ value	6.88961 (rank : 36)	NC score	0.012834 (rank : 45)
Query Neighborhood Hits	45	Target Neighborhood Hits	187	Shared Neighborhood Hits	2
SwissProt Accessions	P55884, Q9UMF9	Gene names	EIF3S9
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116) (eIF3 p110) (eIF3b) (Prt1 homolog) (hPrt1).

MYH4_HUMAN
θ value	6.88961 (rank : 37)	NC score	0.018195 (rank : 39)
Query Neighborhood Hits	45	Target Neighborhood Hits	1377	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

RAD50_MOUSE
θ value	6.88961 (rank : 38)	NC score	0.013982 (rank : 42)
Query Neighborhood Hits	45	Target Neighborhood Hits	1366	Shared Neighborhood Hits	20
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

WRN_MOUSE
θ value	6.88961 (rank : 39)	NC score	0.077588 (rank : 11)
Query Neighborhood Hits	45	Target Neighborhood Hits	295	Shared Neighborhood Hits	19
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

CTRO_HUMAN
θ value	8.99809 (rank : 40)	NC score	0.002819 (rank : 47)
Query Neighborhood Hits	45	Target Neighborhood Hits	2092	Shared Neighborhood Hits	20
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

DDX6_HUMAN
θ value	8.99809 (rank : 41)	NC score	0.034649 (rank : 25)
Query Neighborhood Hits	45	Target Neighborhood Hits	97	Shared Neighborhood Hits	16
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX6_MOUSE
θ value	8.99809 (rank : 42)	NC score	0.034643 (rank : 26)
Query Neighborhood Hits	45	Target Neighborhood Hits	98	Shared Neighborhood Hits	16
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

FANCM_HUMAN
θ value	8.99809 (rank : 43)	NC score	0.032946 (rank : 27)
Query Neighborhood Hits	45	Target Neighborhood Hits	210	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

K0831_HUMAN
θ value	8.99809 (rank : 44)	NC score	0.018755 (rank : 36)
Query Neighborhood Hits	45	Target Neighborhood Hits	203	Shared Neighborhood Hits	10
SwissProt Accessions	Q6ZNE5, O94920	Gene names	KIAA0831
Domain Architecture	No domain graphic available
Description	Protein KIAA0831.

MYH11_MOUSE
θ value	8.99809 (rank : 45)	NC score	0.016284 (rank : 40)
Query Neighborhood Hits	45	Target Neighborhood Hits	1777	Shared Neighborhood Hits	19
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

BLM_HUMAN
θ value	θ > 10 (rank : 46)	NC score	0.052659 (rank : 16)
Query Neighborhood Hits	45	Target Neighborhood Hits	148	Shared Neighborhood Hits	12
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

RECQ5_HUMAN
θ value	θ > 10 (rank : 47)	NC score	0.062823 (rank : 15)
Query Neighborhood Hits	45	Target Neighborhood Hits	390	Shared Neighborhood Hits	14
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

Hits sorted by NC score

SK2L2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	45	Target Neighborhood Hits	45	Shared Neighborhood Hits	45
SwissProt Accessions	Q9CZU3	Gene names	Skiv2l2
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

SK2L2_HUMAN
NC score	0.999051 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	45	Target Neighborhood Hits	36	Shared Neighborhood Hits	35
SwissProt Accessions	P42285, Q8TAG2	Gene names	SKIV2L2, KIAA0052
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

SKIV2_HUMAN
NC score	0.936298 (rank : 3)	θ value	3.26429e-159 (rank : 3)
Query Neighborhood Hits	45	Target Neighborhood Hits	45	Shared Neighborhood Hits	16
SwissProt Accessions	Q15477, O15005, Q12902, Q15476	Gene names	SKIV2L, DDX13, SKI2W, SKIV2, W
Domain Architecture
Description	Helicase SKI2W (EC 3.6.1.-) (Helicase-like protein) (HLP).

HELC1_HUMAN
NC score	0.554084 (rank : 4)	θ value	8.08199e-25 (rank : 4)
Query Neighborhood Hits	45	Target Neighborhood Hits	71	Shared Neighborhood Hits	15
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

U520_HUMAN
NC score	0.531526 (rank : 5)	θ value	3.51386e-20 (rank : 5)
Query Neighborhood Hits	45	Target Neighborhood Hits	88	Shared Neighborhood Hits	15
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

RECQ1_HUMAN
NC score	0.133889 (rank : 6)	θ value	0.00665767 (rank : 6)
Query Neighborhood Hits	45	Target Neighborhood Hits	100	Shared Neighborhood Hits	16
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

RECQ1_MOUSE
NC score	0.115892 (rank : 7)	θ value	0.0736092 (rank : 10)
Query Neighborhood Hits	45	Target Neighborhood Hits	95	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

WRN_HUMAN
NC score	0.104504 (rank : 8)	θ value	0.47712 (rank : 15)
Query Neighborhood Hits	45	Target Neighborhood Hits	132	Shared Neighborhood Hits	19
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

RECQ4_HUMAN
NC score	0.101174 (rank : 9)	θ value	0.365318 (rank : 14)
Query Neighborhood Hits	45	Target Neighborhood Hits	177	Shared Neighborhood Hits	18
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

RECQ4_MOUSE
NC score	0.095831 (rank : 10)	θ value	1.38821 (rank : 19)
Query Neighborhood Hits	45	Target Neighborhood Hits	206	Shared Neighborhood Hits	16
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

WRN_MOUSE
NC score	0.077588 (rank : 11)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	45	Target Neighborhood Hits	295	Shared Neighborhood Hits	19
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

INT1_MOUSE
NC score	0.076283 (rank : 12)	θ value	0.0961366 (rank : 11)
Query Neighborhood Hits	45	Target Neighborhood Hits	44	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P4S8, Q80UQ7, Q91Z01, Q9CTF7	Gene names	Ints1
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 1 (Int1).

DDX54_HUMAN
NC score	0.066072 (rank : 13)	θ value	0.0113563 (rank : 7)
Query Neighborhood Hits	45	Target Neighborhood Hits	170	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

DDX54_MOUSE
NC score	0.063154 (rank : 14)	θ value	0.0193708 (rank : 8)
Query Neighborhood Hits	45	Target Neighborhood Hits	124	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

RECQ5_HUMAN
NC score	0.062823 (rank : 15)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	45	Target Neighborhood Hits	390	Shared Neighborhood Hits	14
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

BLM_HUMAN
NC score	0.052659 (rank : 16)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	45	Target Neighborhood Hits	148	Shared Neighborhood Hits	12
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

DHX36_MOUSE
NC score	0.051944 (rank : 17)	θ value	0.0252991 (rank : 9)
Query Neighborhood Hits	45	Target Neighborhood Hits	114	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VHK9, Q6ZPP7, Q9CSE8	Gene names	Dhx36, Ddx36, Kiaa1488, Mlel1
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

DHX36_HUMAN
NC score	0.051711 (rank : 18)	θ value	0.21417 (rank : 12)
Query Neighborhood Hits	45	Target Neighborhood Hits	63	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H2U1, Q70JU3, Q8IYE5, Q9P240	Gene names	DHX36, DDX36, KIAA1488, MLEL1, RHAU
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

PGES2_HUMAN
NC score	0.049779 (rank : 19)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	45	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H7Z7, Q53EW9, Q5SYV6, Q96GI0, Q96GL2	Gene names	PTGES2, PGES2
Domain Architecture	No domain graphic available
Description	Prostaglandin E synthase 2 (EC 5.3.99.3) (Microsomal prostaglandin E synthase 2) (mPGES-2) [Contains: Prostaglandin E synthase 2 truncated form].

CV106_HUMAN
NC score	0.047896 (rank : 20)	θ value	2.36792 (rank : 21)
Query Neighborhood Hits	45	Target Neighborhood Hits	125	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P0N0, Q86V14, Q96PY4, Q9NUR5, Q9Y4X9	Gene names	C14orf106, KIAA1903
Domain Architecture	No domain graphic available
Description	Protein C14orf106 (P243).

PGES2_MOUSE
NC score	0.046343 (rank : 21)	θ value	4.03905 (rank : 28)
Query Neighborhood Hits	45	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BWM0, Q99J30	Gene names	Ptges2, Gbf1, Pges2
Domain Architecture	No domain graphic available
Description	Prostaglandin E synthase 2 (EC 5.3.99.3) (Microsomal prostaglandin E synthase 2) (mPGES-2) (GATE-binding factor 1) (GBF-1) [Contains: Prostaglandin E synthase 2 truncated form].

K0841_HUMAN
NC score	0.045369 (rank : 22)	θ value	1.06291 (rank : 16)
Query Neighborhood Hits	45	Target Neighborhood Hits	119	Shared Neighborhood Hits	9
SwissProt Accessions	O94927, Q6P2P7, Q7L3D5, Q96CT8	Gene names	KIAA0841
Domain Architecture	No domain graphic available
Description	Protein KIAA0841.

DDX52_HUMAN
NC score	0.036729 (rank : 23)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	45	Target Neighborhood Hits	107	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

MYO5B_HUMAN
NC score	0.034924 (rank : 24)	θ value	0.279714 (rank : 13)
Query Neighborhood Hits	45	Target Neighborhood Hits	911	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

DDX6_HUMAN
NC score	0.034649 (rank : 25)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	45	Target Neighborhood Hits	97	Shared Neighborhood Hits	16
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX6_MOUSE
NC score	0.034643 (rank : 26)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	45	Target Neighborhood Hits	98	Shared Neighborhood Hits	16
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

FANCM_HUMAN
NC score	0.032946 (rank : 27)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	45	Target Neighborhood Hits	210	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

MYO5A_MOUSE
NC score	0.030955 (rank : 28)	θ value	1.06291 (rank : 18)
Query Neighborhood Hits	45	Target Neighborhood Hits	1117	Shared Neighborhood Hits	17
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

MYO5A_HUMAN
NC score	0.030852 (rank : 29)	θ value	1.06291 (rank : 17)
Query Neighborhood Hits	45	Target Neighborhood Hits	1092	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

MYO5C_HUMAN
NC score	0.026608 (rank : 30)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	45	Target Neighborhood Hits	1206	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

DHX8_HUMAN
NC score	0.023028 (rank : 31)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	45	Target Neighborhood Hits	86	Shared Neighborhood Hits	7
SwissProt Accessions	Q14562	Gene names	DHX8, DDX8
Domain Architecture
Description	ATP-dependent RNA helicase DHX8 (EC 3.6.1.-) (DEAH box protein 8) (RNA helicase HRH1).

MY18B_HUMAN
NC score	0.022752 (rank : 32)	θ value	1.81305 (rank : 20)
Query Neighborhood Hits	45	Target Neighborhood Hits	1299	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

DNJC3_HUMAN
NC score	0.021306 (rank : 33)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	45	Target Neighborhood Hits	223	Shared Neighborhood Hits	10
SwissProt Accessions	Q13217, Q86WT9, Q8N4N2	Gene names	DNAJC3, P58IPK, PRKRI
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 3 (Interferon-induced, double-stranded RNA-activated protein kinase inhibitor) (Protein kinase inhibitor p58) (Protein kinase inhibitor of 58 kDa).

DNJC3_MOUSE
NC score	0.021010 (rank : 34)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	45	Target Neighborhood Hits	230	Shared Neighborhood Hits	8
SwissProt Accessions	Q91YW3, Q60873	Gene names	Dnajc3, P58ipk
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 3 (Interferon-induced, double-stranded RNA-activated protein kinase inhibitor) (Protein kinase inhibitor p58) (Protein kinase inhibitor of 58 kDa).

CR034_MOUSE
NC score	0.020610 (rank : 35)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	45	Target Neighborhood Hits	643	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CDV0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34 homolog.

K0831_HUMAN
NC score	0.018755 (rank : 36)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	45	Target Neighborhood Hits	203	Shared Neighborhood Hits	10
SwissProt Accessions	Q6ZNE5, O94920	Gene names	KIAA0831
Domain Architecture	No domain graphic available
Description	Protein KIAA0831.

MYH6_HUMAN
NC score	0.018386 (rank : 37)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	45	Target Neighborhood Hits	1426	Shared Neighborhood Hits	18
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH4_MOUSE
NC score	0.018364 (rank : 38)	θ value	4.03905 (rank : 26)
Query Neighborhood Hits	45	Target Neighborhood Hits	1476	Shared Neighborhood Hits	17
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

MYH4_HUMAN
NC score	0.018195 (rank : 39)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	45	Target Neighborhood Hits	1377	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

MYH11_MOUSE
NC score	0.016284 (rank : 40)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	45	Target Neighborhood Hits	1777	Shared Neighborhood Hits	19
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

RAD50_HUMAN
NC score	0.014756 (rank : 41)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	45	Target Neighborhood Hits	1317	Shared Neighborhood Hits	18
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

RAD50_MOUSE
NC score	0.013982 (rank : 42)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	45	Target Neighborhood Hits	1366	Shared Neighborhood Hits	20
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

JAD1D_MOUSE
NC score	0.013376 (rank : 43)	θ value	3.0926 (rank : 22)
Query Neighborhood Hits	45	Target Neighborhood Hits	228	Shared Neighborhood Hits	5
SwissProt Accessions	Q62240, Q9QVR9, Q9R040	Gene names	Smcy, Hya, Jarid1d
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

CCD41_MOUSE
NC score	0.013097 (rank : 44)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	45	Target Neighborhood Hits	1399	Shared Neighborhood Hits	22
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

IF39_HUMAN
NC score	0.012834 (rank : 45)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	45	Target Neighborhood Hits	187	Shared Neighborhood Hits	2
SwissProt Accessions	P55884, Q9UMF9	Gene names	EIF3S9
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116) (eIF3 p110) (eIF3b) (Prt1 homolog) (hPrt1).

TLR11_MOUSE
NC score	0.012376 (rank : 46)	θ value	3.0926 (rank : 25)
Query Neighborhood Hits	45	Target Neighborhood Hits	293	Shared Neighborhood Hits	3
SwissProt Accessions	Q6R5P0	Gene names	Tlr11
Domain Architecture	No domain graphic available
Description	Toll-like receptor 11 precursor.

CTRO_HUMAN
NC score	0.002819 (rank : 47)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	45	Target Neighborhood Hits	2092	Shared Neighborhood Hits	20
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).