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Network neighborhood for query Sequence : EXO1_HUMAN

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EXO1_HUMAN
SwissProt Accessions	Q9UQ84, O60545, O75214, O75466, Q5T396, Q96IJ1, Q9UG38, Q9UNW0	Gene names	EXO1, EXOI, HEX1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (hExo1) (Exonuclease I) (hExoI).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

EXO1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	82	Target Neighborhood Hits	82	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UQ84, O60545, O75214, O75466, Q5T396, Q96IJ1, Q9UG38, Q9UNW0	Gene names	EXO1, EXOI, HEX1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (hExo1) (Exonuclease I) (hExoI).

EXO1_MOUSE
θ value	0 (rank : 2)	NC score	0.955221 (rank : 2)
Query Neighborhood Hits	82	Target Neighborhood Hits	89	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QZ11, Q3TLM4, Q923A5	Gene names	Exo1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (mExo1) (Exonuclease I).

FEN1_HUMAN
θ value	8.65492e-19 (rank : 3)	NC score	0.588467 (rank : 3)
Query Neighborhood Hits	82	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	P39748	Gene names	FEN1
Domain Architecture
Description	Flap endonuclease 1 (EC 3.1.-.-) (Flap structure-specific endonuclease 1) (FEN-1) (Maturation factor 1) (MF1) (hFEN-1) (DNase IV).

FEN1_MOUSE
θ value	2.13179e-17 (rank : 4)	NC score	0.575879 (rank : 4)
Query Neighborhood Hits	82	Target Neighborhood Hits	17	Shared Neighborhood Hits	6
SwissProt Accessions	P39749	Gene names	Fen1, Fen-1
Domain Architecture
Description	Flap endonuclease 1 (EC 3.1.-.-) (Flap structure-specific endonuclease 1) (FEN-1).

DMP1_MOUSE
θ value	8.40245e-06 (rank : 5)	NC score	0.183826 (rank : 7)
Query Neighborhood Hits	82	Target Neighborhood Hits	498	Shared Neighborhood Hits	29
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

DSPP_HUMAN
θ value	3.19293e-05 (rank : 6)	NC score	0.160419 (rank : 9)
Query Neighborhood Hits	82	Target Neighborhood Hits	645	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

ERCC5_HUMAN
θ value	0.000270298 (rank : 7)	NC score	0.267943 (rank : 6)
Query Neighborhood Hits	82	Target Neighborhood Hits	162	Shared Neighborhood Hits	11
SwissProt Accessions	P28715, Q7Z2V3, Q8IZL6, Q8N1B7, Q9HD59	Gene names	ERCC5, XPG, XPGC
Domain Architecture
Description	DNA-repair protein complementing XP-G cells (Xeroderma pigmentosum group G-complementing protein) (DNA excision repair protein ERCC-5).

ERCC5_MOUSE
θ value	0.000270298 (rank : 8)	NC score	0.275983 (rank : 5)
Query Neighborhood Hits	82	Target Neighborhood Hits	206	Shared Neighborhood Hits	21
SwissProt Accessions	P35689, Q61528, Q64248	Gene names	Ercc5, Ercc-5, Xpg
Domain Architecture
Description	DNA-repair protein complementing XP-G cells homolog (Xeroderma pigmentosum group G-complementing protein homolog) (DNA excision repair protein ERCC-5).

ATRX_MOUSE
θ value	0.00102713 (rank : 9)	NC score	0.084314 (rank : 15)
Query Neighborhood Hits	82	Target Neighborhood Hits	682	Shared Neighborhood Hits	28
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

BRCA2_MOUSE
θ value	0.00102713 (rank : 10)	NC score	0.114758 (rank : 11)
Query Neighborhood Hits	82	Target Neighborhood Hits	222	Shared Neighborhood Hits	15
SwissProt Accessions	P97929, O35922, P97383	Gene names	Brca2, Fancd1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein homolog (Fanconi anemia group D1 protein homolog).

EMAL4_HUMAN
θ value	0.00298849 (rank : 11)	NC score	0.060020 (rank : 18)
Query Neighborhood Hits	82	Target Neighborhood Hits	306	Shared Neighborhood Hits	7
SwissProt Accessions	Q9HC35	Gene names	EML4, C2orf2, EMAPL4
Domain Architecture
Description	Echinoderm microtubule-associated protein-like 4 (EMAP-4) (Restrictedly overexpressed proliferation-associated protein) (Ropp 120).

DSPP_MOUSE
θ value	0.00665767 (rank : 12)	NC score	0.169968 (rank : 8)
Query Neighborhood Hits	82	Target Neighborhood Hits	491	Shared Neighborhood Hits	21
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

IWS1_HUMAN
θ value	0.0113563 (rank : 13)	NC score	0.102450 (rank : 12)
Query Neighborhood Hits	82	Target Neighborhood Hits	1241	Shared Neighborhood Hits	42
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

CN155_HUMAN
θ value	0.0330416 (rank : 14)	NC score	0.076334 (rank : 17)
Query Neighborhood Hits	82	Target Neighborhood Hits	385	Shared Neighborhood Hits	18
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

IWS1_MOUSE
θ value	0.0330416 (rank : 15)	NC score	0.093264 (rank : 13)
Query Neighborhood Hits	82	Target Neighborhood Hits	1258	Shared Neighborhood Hits	37
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

DMP1_HUMAN
θ value	0.0736092 (rank : 16)	NC score	0.140845 (rank : 10)
Query Neighborhood Hits	82	Target Neighborhood Hits	491	Shared Neighborhood Hits	25
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

NUDT8_HUMAN
θ value	0.125558 (rank : 17)	NC score	0.078384 (rank : 16)
Query Neighborhood Hits	82	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WV74, Q6ZW59	Gene names	NUDT8
Domain Architecture	No domain graphic available
Description	Nucleoside diphosphate-linked moiety X motif 8, mitochondrial precursor (EC 3.6.1.-) (Nudix motif 8).

SYBU_MOUSE
θ value	0.125558 (rank : 18)	NC score	0.053173 (rank : 22)
Query Neighborhood Hits	82	Target Neighborhood Hits	214	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHS8, Q3TQN7, Q401F3, Q401F4, Q571C1, Q6P1J2, Q80XH0, Q8BHS7, Q8BI27	Gene names	Sybu, Golsyn, Kiaa1472
Domain Architecture	No domain graphic available
Description	Syntabulin (Syntaxin-1-binding protein) (Golgi-localized syntaphilin- related protein) (m-Golsyn).

SRRM2_HUMAN
θ value	0.21417 (rank : 19)	NC score	0.056483 (rank : 19)
Query Neighborhood Hits	82	Target Neighborhood Hits	1296	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

BRCA2_HUMAN
θ value	0.47712 (rank : 20)	NC score	0.086238 (rank : 14)
Query Neighborhood Hits	82	Target Neighborhood Hits	202	Shared Neighborhood Hits	8
SwissProt Accessions	P51587, O00183, O15008, Q13879	Gene names	BRCA2, FANCD1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein).

SDPR_HUMAN
θ value	0.47712 (rank : 21)	NC score	0.040360 (rank : 34)
Query Neighborhood Hits	82	Target Neighborhood Hits	337	Shared Neighborhood Hits	14
SwissProt Accessions	O95810	Gene names	SDPR
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein) (PS-p68).

CENPC_HUMAN
θ value	0.62314 (rank : 22)	NC score	0.050109 (rank : 28)
Query Neighborhood Hits	82	Target Neighborhood Hits	147	Shared Neighborhood Hits	11
SwissProt Accessions	Q03188, Q9P0M5	Gene names	CENPC1, CENPC, ICEN7
Domain Architecture	No domain graphic available
Description	Centromere protein C 1 (CENP-C) (Centromere autoantigen C) (Interphase centromere complex protein 7).

DDX20_MOUSE
θ value	0.62314 (rank : 23)	NC score	0.017088 (rank : 61)
Query Neighborhood Hits	82	Target Neighborhood Hits	177	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

ACINU_HUMAN
θ value	0.813845 (rank : 24)	NC score	0.051827 (rank : 25)
Query Neighborhood Hits	82	Target Neighborhood Hits	828	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

GOGA3_HUMAN
θ value	0.813845 (rank : 25)	NC score	0.012239 (rank : 70)
Query Neighborhood Hits	82	Target Neighborhood Hits	1317	Shared Neighborhood Hits	14
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

RIOK2_MOUSE
θ value	0.813845 (rank : 26)	NC score	0.043008 (rank : 31)
Query Neighborhood Hits	82	Target Neighborhood Hits	82	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CQS5, Q91XF3	Gene names	Riok2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2).

EP15R_MOUSE
θ value	1.06291 (rank : 27)	NC score	0.017576 (rank : 60)
Query Neighborhood Hits	82	Target Neighborhood Hits	1135	Shared Neighborhood Hits	18
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

KSR1_MOUSE
θ value	1.38821 (rank : 28)	NC score	0.006625 (rank : 77)
Query Neighborhood Hits	82	Target Neighborhood Hits	870	Shared Neighborhood Hits	6
SwissProt Accessions	Q61097, Q61648, Q78DX8	Gene names	Ksr1, Ksr
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras) (mKSR1) (Hb protein).

RN169_HUMAN
θ value	1.38821 (rank : 29)	NC score	0.041703 (rank : 32)
Query Neighborhood Hits	82	Target Neighborhood Hits	203	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

BRD2_HUMAN
θ value	1.81305 (rank : 30)	NC score	0.024912 (rank : 47)
Query Neighborhood Hits	82	Target Neighborhood Hits	242	Shared Neighborhood Hits	15
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

BRPF1_HUMAN
θ value	1.81305 (rank : 31)	NC score	0.034906 (rank : 37)
Query Neighborhood Hits	82	Target Neighborhood Hits	259	Shared Neighborhood Hits	11
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

CENPR_MOUSE
θ value	1.81305 (rank : 32)	NC score	0.044255 (rank : 29)
Query Neighborhood Hits	82	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CQ82, Q3TLR0, Q3TNR4	Gene names	Itgb3bp, Cenpr, Nrif3
Domain Architecture	No domain graphic available
Description	Centromere protein R (CENP-R) (Nuclear receptor-interacting factor 3).

M2GD_MOUSE
θ value	1.81305 (rank : 33)	NC score	0.043782 (rank : 30)
Query Neighborhood Hits	82	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBT9, Q8R1S7	Gene names	Dmgdh
Domain Architecture
Description	Dimethylglycine dehydrogenase, mitochondrial precursor (EC 1.5.99.2) (ME2GLYDH).

PRDM2_HUMAN
θ value	1.81305 (rank : 34)	NC score	0.011357 (rank : 72)
Query Neighborhood Hits	82	Target Neighborhood Hits	1135	Shared Neighborhood Hits	15
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

WRN_MOUSE
θ value	1.81305 (rank : 35)	NC score	0.023482 (rank : 51)
Query Neighborhood Hits	82	Target Neighborhood Hits	295	Shared Neighborhood Hits	10
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

BCL7A_HUMAN
θ value	2.36792 (rank : 36)	NC score	0.039421 (rank : 35)
Query Neighborhood Hits	82	Target Neighborhood Hits	35	Shared Neighborhood Hits	5
SwissProt Accessions	Q4VC05, Q13843	Gene names	BCL7A
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member A.

CJ078_MOUSE
θ value	2.36792 (rank : 37)	NC score	0.054243 (rank : 21)
Query Neighborhood Hits	82	Target Neighborhood Hits	559	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CS021_MOUSE
θ value	2.36792 (rank : 38)	NC score	0.031148 (rank : 42)
Query Neighborhood Hits	82	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D279, Q3UI04	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf21 homolog.

M2GD_HUMAN
θ value	2.36792 (rank : 39)	NC score	0.041408 (rank : 33)
Query Neighborhood Hits	82	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UI17	Gene names	DMGDH
Domain Architecture
Description	Dimethylglycine dehydrogenase, mitochondrial precursor (EC 1.5.99.2) (ME2GLYDH).

MAK_HUMAN
θ value	2.36792 (rank : 40)	NC score	0.001537 (rank : 81)
Query Neighborhood Hits	82	Target Neighborhood Hits	857	Shared Neighborhood Hits	3
SwissProt Accessions	P20794, Q9NUH7	Gene names	MAK
Domain Architecture
Description	Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male germ cell- associated kinase).

MAP1B_MOUSE
θ value	2.36792 (rank : 41)	NC score	0.050128 (rank : 27)
Query Neighborhood Hits	82	Target Neighborhood Hits	977	Shared Neighborhood Hits	29
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

AP3B1_MOUSE
θ value	3.0926 (rank : 42)	NC score	0.034107 (rank : 39)
Query Neighborhood Hits	82	Target Neighborhood Hits	302	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

APC_HUMAN
θ value	3.0926 (rank : 43)	NC score	0.039098 (rank : 36)
Query Neighborhood Hits	82	Target Neighborhood Hits	603	Shared Neighborhood Hits	18
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

DHX9_MOUSE
θ value	3.0926 (rank : 44)	NC score	0.011189 (rank : 73)
Query Neighborhood Hits	82	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	O70133, O35931, O54703, Q5FWY1, Q6R5F7, Q9CSA2	Gene names	Dhx9, Ddx9
Domain Architecture
Description	ATP-dependent RNA helicase A (EC 3.6.1.-) (Nuclear DNA helicase II) (NDH II) (DEAH box protein 9) (mHEL-5).

GP112_HUMAN
θ value	3.0926 (rank : 45)	NC score	0.015486 (rank : 64)
Query Neighborhood Hits	82	Target Neighborhood Hits	441	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

HRX_HUMAN
θ value	3.0926 (rank : 46)	NC score	0.023586 (rank : 50)
Query Neighborhood Hits	82	Target Neighborhood Hits	825	Shared Neighborhood Hits	21
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

MAP1B_HUMAN
θ value	3.0926 (rank : 47)	NC score	0.050403 (rank : 26)
Query Neighborhood Hits	82	Target Neighborhood Hits	903	Shared Neighborhood Hits	32
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

AFF2_MOUSE
θ value	4.03905 (rank : 48)	NC score	0.025392 (rank : 45)
Query Neighborhood Hits	82	Target Neighborhood Hits	225	Shared Neighborhood Hits	14
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

BCL7A_MOUSE
θ value	4.03905 (rank : 49)	NC score	0.034799 (rank : 38)
Query Neighborhood Hits	82	Target Neighborhood Hits	74	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CXE2, Q8C361, Q8C8M8, Q8VD15	Gene names	Bcl7a
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member A.

BSN_MOUSE
θ value	4.03905 (rank : 50)	NC score	0.021707 (rank : 54)
Query Neighborhood Hits	82	Target Neighborhood Hits	2057	Shared Neighborhood Hits	32
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CE110_MOUSE
θ value	4.03905 (rank : 51)	NC score	0.022079 (rank : 53)
Query Neighborhood Hits	82	Target Neighborhood Hits	170	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TSH4, Q6A072	Gene names	Cep110, Cp110, Kiaa0419
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 110 kDa (Cep110 protein).

DMXL1_HUMAN
θ value	4.03905 (rank : 52)	NC score	0.014054 (rank : 66)
Query Neighborhood Hits	82	Target Neighborhood Hits	259	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y485	Gene names	DMXL1, XL1
Domain Architecture	No domain graphic available
Description	Protein DmX-like 1 (X-like 1 protein).

LIPA4_HUMAN
θ value	4.03905 (rank : 53)	NC score	0.013500 (rank : 69)
Query Neighborhood Hits	82	Target Neighborhood Hits	56	Shared Neighborhood Hits	2
SwissProt Accessions	O75335, O94971	Gene names	PPFIA4, KIAA0897
Domain Architecture
Description	Liprin-alpha-4 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-4) (PTPRF-interacting protein alpha-4).

MYCB2_MOUSE
θ value	4.03905 (rank : 54)	NC score	0.018221 (rank : 59)
Query Neighborhood Hits	82	Target Neighborhood Hits	307	Shared Neighborhood Hits	9
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

NU153_HUMAN
θ value	4.03905 (rank : 55)	NC score	0.033847 (rank : 41)
Query Neighborhood Hits	82	Target Neighborhood Hits	227	Shared Neighborhood Hits	12
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

ABRA_HUMAN
θ value	5.27518 (rank : 56)	NC score	0.022549 (rank : 52)
Query Neighborhood Hits	82	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N0Z2	Gene names	ABRA
Domain Architecture	No domain graphic available
Description	Actin-binding Rho-activating protein (Striated muscle activator of Rho-dependent signaling) (STARS).

BRPF3_HUMAN
θ value	5.27518 (rank : 57)	NC score	0.020916 (rank : 56)
Query Neighborhood Hits	82	Target Neighborhood Hits	217	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

DCR1A_HUMAN
θ value	5.27518 (rank : 58)	NC score	0.018322 (rank : 58)
Query Neighborhood Hits	82	Target Neighborhood Hits	43	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PJP8, Q14701, Q6P5Y3, Q6PKL4	Gene names	DCLRE1A, KIAA0086, SNM1, SNM1A
Domain Architecture	No domain graphic available
Description	DNA cross-link repair 1A protein (hSNM1) (hSNM1A).

GLI2_HUMAN
θ value	5.27518 (rank : 59)	NC score	0.001368 (rank : 83)
Query Neighborhood Hits	82	Target Neighborhood Hits	971	Shared Neighborhood Hits	10
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

INCE_MOUSE
θ value	5.27518 (rank : 60)	NC score	0.011008 (rank : 74)
Query Neighborhood Hits	82	Target Neighborhood Hits	903	Shared Neighborhood Hits	14
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

IRK14_HUMAN
θ value	5.27518 (rank : 61)	NC score	0.010145 (rank : 75)
Query Neighborhood Hits	82	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UNX9	Gene names	KCNJ14
Domain Architecture	No domain graphic available
Description	ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4).

MRP4_HUMAN
θ value	5.27518 (rank : 62)	NC score	0.005780 (rank : 79)
Query Neighborhood Hits	82	Target Neighborhood Hits	107	Shared Neighborhood Hits	2
SwissProt Accessions	O15439, Q9Y6J2	Gene names	ABCC4, MRP4
Domain Architecture
Description	Multidrug resistance-associated protein 4 (ATP-binding cassette sub- family C member 4) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter-B) (MOAT-B).

NKTR_HUMAN
θ value	5.27518 (rank : 63)	NC score	0.030172 (rank : 43)
Query Neighborhood Hits	82	Target Neighborhood Hits	658	Shared Neighborhood Hits	32
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

RRP44_HUMAN
θ value	5.27518 (rank : 64)	NC score	0.025017 (rank : 46)
Query Neighborhood Hits	82	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2L1, Q5W0P7, Q5W0P8, Q658Z7, Q7Z481, Q8WWI2, Q9UG36	Gene names	DIS3, KIAA1008, RRP44
Domain Architecture
Description	Exosome complex exonuclease RRP44 (EC 3.1.13.-) (Ribosomal RNA- processing protein 44) (DIS3 protein homolog).

RSRC1_HUMAN
θ value	5.27518 (rank : 65)	NC score	0.029661 (rank : 44)
Query Neighborhood Hits	82	Target Neighborhood Hits	108	Shared Neighborhood Hits	7
SwissProt Accessions	Q96IZ7, Q96QK2, Q9NZE5	Gene names	RSRC1
Domain Architecture	No domain graphic available
Description	Arginine/serine-rich coiled coil protein 1.

ATRX_HUMAN
θ value	6.88961 (rank : 66)	NC score	0.054358 (rank : 20)
Query Neighborhood Hits	82	Target Neighborhood Hits	842	Shared Neighborhood Hits	28
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

MYPT1_MOUSE
θ value	6.88961 (rank : 67)	NC score	0.007432 (rank : 76)
Query Neighborhood Hits	82	Target Neighborhood Hits	539	Shared Neighborhood Hits	12
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

PALB2_MOUSE
θ value	6.88961 (rank : 68)	NC score	0.016435 (rank : 63)
Query Neighborhood Hits	82	Target Neighborhood Hits	133	Shared Neighborhood Hits	5
SwissProt Accessions	Q3U0P1, Q6NZG9, Q7TMQ4, Q8CEA9	Gene names	Palb2
Domain Architecture	No domain graphic available
Description	Partner and localizer of BRCA2.

SRRM2_MOUSE
θ value	6.88961 (rank : 69)	NC score	0.052339 (rank : 23)
Query Neighborhood Hits	82	Target Neighborhood Hits	1470	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TSH2_HUMAN
θ value	6.88961 (rank : 70)	NC score	0.013701 (rank : 68)
Query Neighborhood Hits	82	Target Neighborhood Hits	479	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NRE2, Q4VXM4, Q6N003, Q8N260	Gene names	TSHZ2, C20orf17, TSH2, ZNF218
Domain Architecture	No domain graphic available
Description	Teashirt homolog 2 (Zinc finger protein 218) (Ovarian cancer-related protein 10-2) (OVC10-2).

ZN318_MOUSE
θ value	6.88961 (rank : 71)	NC score	0.021023 (rank : 55)
Query Neighborhood Hits	82	Target Neighborhood Hits	642	Shared Neighborhood Hits	19
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

AP3B1_HUMAN
θ value	8.99809 (rank : 72)	NC score	0.034027 (rank : 40)
Query Neighborhood Hits	82	Target Neighborhood Hits	283	Shared Neighborhood Hits	19
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

BRWD1_MOUSE
θ value	8.99809 (rank : 73)	NC score	0.016546 (rank : 62)
Query Neighborhood Hits	82	Target Neighborhood Hits	478	Shared Neighborhood Hits	17
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

CA026_HUMAN
θ value	8.99809 (rank : 74)	NC score	0.013747 (rank : 67)
Query Neighborhood Hits	82	Target Neighborhood Hits	87	Shared Neighborhood Hits	5
SwissProt Accessions	Q5T5J6, Q8NEK9, Q9BZQ7, Q9NXQ0	Gene names	C1orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf26.

CENPU_HUMAN
θ value	8.99809 (rank : 75)	NC score	0.024807 (rank : 48)
Query Neighborhood Hits	82	Target Neighborhood Hits	289	Shared Neighborhood Hits	14
SwissProt Accessions	Q71F23, Q32Q71, Q9H5G1	Gene names	MLF1IP, CENPU, ICEN24, KLIP1
Domain Architecture	No domain graphic available
Description	Centromere protein U (CENP-U) (CENP-U(50)) (CENP-50) (Interphase centromere complex protein 24) (MLF1-interacting protein) (KSHV latent nuclear antigen-interacting protein 1).

CSPG2_MOUSE
θ value	8.99809 (rank : 76)	NC score	0.005875 (rank : 78)
Query Neighborhood Hits	82	Target Neighborhood Hits	711	Shared Neighborhood Hits	9
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

FACD2_HUMAN
θ value	8.99809 (rank : 77)	NC score	0.014255 (rank : 65)
Query Neighborhood Hits	82	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BXW9, Q2LA86, Q69YP9, Q6PJN7, Q9BQ06, Q9H9T9	Gene names	FANCD2
Domain Architecture	No domain graphic available
Description	Fanconi anemia group D2 protein (Protein FACD2).

IP3KB_HUMAN
θ value	8.99809 (rank : 78)	NC score	0.012178 (rank : 71)
Query Neighborhood Hits	82	Target Neighborhood Hits	124	Shared Neighborhood Hits	6
SwissProt Accessions	P27987, Q5VWL9, Q5VWM0, Q96BZ2, Q96JS1, Q9UH47	Gene names	ITPKB
Domain Architecture
Description	Inositol-trisphosphate 3-kinase B (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase B) (IP3K B) (IP3 3-kinase B) (IP3K-B).

IRAK3_MOUSE
θ value	8.99809 (rank : 79)	NC score	0.001532 (rank : 82)
Query Neighborhood Hits	82	Target Neighborhood Hits	628	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K4B2, Q8C7U8, Q8CE40, Q8K1S8	Gene names	Irak3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

MAP4_MOUSE
θ value	8.99809 (rank : 80)	NC score	0.018731 (rank : 57)
Query Neighborhood Hits	82	Target Neighborhood Hits	409	Shared Neighborhood Hits	16
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

SDK1_MOUSE
θ value	8.99809 (rank : 81)	NC score	0.001718 (rank : 80)
Query Neighborhood Hits	82	Target Neighborhood Hits	495	Shared Neighborhood Hits	4
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SFR12_HUMAN
θ value	8.99809 (rank : 82)	NC score	0.023634 (rank : 49)
Query Neighborhood Hits	82	Target Neighborhood Hits	553	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

LEO1_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.051922 (rank : 24)
Query Neighborhood Hits	82	Target Neighborhood Hits	958	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

Hits sorted by NC score

EXO1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	82	Target Neighborhood Hits	82	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UQ84, O60545, O75214, O75466, Q5T396, Q96IJ1, Q9UG38, Q9UNW0	Gene names	EXO1, EXOI, HEX1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (hExo1) (Exonuclease I) (hExoI).

EXO1_MOUSE
NC score	0.955221 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	82	Target Neighborhood Hits	89	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QZ11, Q3TLM4, Q923A5	Gene names	Exo1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (mExo1) (Exonuclease I).

FEN1_HUMAN
NC score	0.588467 (rank : 3)	θ value	8.65492e-19 (rank : 3)
Query Neighborhood Hits	82	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	P39748	Gene names	FEN1
Domain Architecture
Description	Flap endonuclease 1 (EC 3.1.-.-) (Flap structure-specific endonuclease 1) (FEN-1) (Maturation factor 1) (MF1) (hFEN-1) (DNase IV).

FEN1_MOUSE
NC score	0.575879 (rank : 4)	θ value	2.13179e-17 (rank : 4)
Query Neighborhood Hits	82	Target Neighborhood Hits	17	Shared Neighborhood Hits	6
SwissProt Accessions	P39749	Gene names	Fen1, Fen-1
Domain Architecture
Description	Flap endonuclease 1 (EC 3.1.-.-) (Flap structure-specific endonuclease 1) (FEN-1).

ERCC5_MOUSE
NC score	0.275983 (rank : 5)	θ value	0.000270298 (rank : 8)
Query Neighborhood Hits	82	Target Neighborhood Hits	206	Shared Neighborhood Hits	21
SwissProt Accessions	P35689, Q61528, Q64248	Gene names	Ercc5, Ercc-5, Xpg
Domain Architecture
Description	DNA-repair protein complementing XP-G cells homolog (Xeroderma pigmentosum group G-complementing protein homolog) (DNA excision repair protein ERCC-5).

ERCC5_HUMAN
NC score	0.267943 (rank : 6)	θ value	0.000270298 (rank : 7)
Query Neighborhood Hits	82	Target Neighborhood Hits	162	Shared Neighborhood Hits	11
SwissProt Accessions	P28715, Q7Z2V3, Q8IZL6, Q8N1B7, Q9HD59	Gene names	ERCC5, XPG, XPGC
Domain Architecture
Description	DNA-repair protein complementing XP-G cells (Xeroderma pigmentosum group G-complementing protein) (DNA excision repair protein ERCC-5).

DMP1_MOUSE
NC score	0.183826 (rank : 7)	θ value	8.40245e-06 (rank : 5)
Query Neighborhood Hits	82	Target Neighborhood Hits	498	Shared Neighborhood Hits	29
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

DSPP_MOUSE
NC score	0.169968 (rank : 8)	θ value	0.00665767 (rank : 12)
Query Neighborhood Hits	82	Target Neighborhood Hits	491	Shared Neighborhood Hits	21
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

DSPP_HUMAN
NC score	0.160419 (rank : 9)	θ value	3.19293e-05 (rank : 6)
Query Neighborhood Hits	82	Target Neighborhood Hits	645	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

DMP1_HUMAN
NC score	0.140845 (rank : 10)	θ value	0.0736092 (rank : 16)
Query Neighborhood Hits	82	Target Neighborhood Hits	491	Shared Neighborhood Hits	25
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

BRCA2_MOUSE
NC score	0.114758 (rank : 11)	θ value	0.00102713 (rank : 10)
Query Neighborhood Hits	82	Target Neighborhood Hits	222	Shared Neighborhood Hits	15
SwissProt Accessions	P97929, O35922, P97383	Gene names	Brca2, Fancd1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein homolog (Fanconi anemia group D1 protein homolog).

IWS1_HUMAN
NC score	0.102450 (rank : 12)	θ value	0.0113563 (rank : 13)
Query Neighborhood Hits	82	Target Neighborhood Hits	1241	Shared Neighborhood Hits	42
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

IWS1_MOUSE
NC score	0.093264 (rank : 13)	θ value	0.0330416 (rank : 15)
Query Neighborhood Hits	82	Target Neighborhood Hits	1258	Shared Neighborhood Hits	37
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

BRCA2_HUMAN
NC score	0.086238 (rank : 14)	θ value	0.47712 (rank : 20)
Query Neighborhood Hits	82	Target Neighborhood Hits	202	Shared Neighborhood Hits	8
SwissProt Accessions	P51587, O00183, O15008, Q13879	Gene names	BRCA2, FANCD1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein).

ATRX_MOUSE
NC score	0.084314 (rank : 15)	θ value	0.00102713 (rank : 9)
Query Neighborhood Hits	82	Target Neighborhood Hits	682	Shared Neighborhood Hits	28
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

NUDT8_HUMAN
NC score	0.078384 (rank : 16)	θ value	0.125558 (rank : 17)
Query Neighborhood Hits	82	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WV74, Q6ZW59	Gene names	NUDT8
Domain Architecture	No domain graphic available
Description	Nucleoside diphosphate-linked moiety X motif 8, mitochondrial precursor (EC 3.6.1.-) (Nudix motif 8).

CN155_HUMAN
NC score	0.076334 (rank : 17)	θ value	0.0330416 (rank : 14)
Query Neighborhood Hits	82	Target Neighborhood Hits	385	Shared Neighborhood Hits	18
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

EMAL4_HUMAN
NC score	0.060020 (rank : 18)	θ value	0.00298849 (rank : 11)
Query Neighborhood Hits	82	Target Neighborhood Hits	306	Shared Neighborhood Hits	7
SwissProt Accessions	Q9HC35	Gene names	EML4, C2orf2, EMAPL4
Domain Architecture
Description	Echinoderm microtubule-associated protein-like 4 (EMAP-4) (Restrictedly overexpressed proliferation-associated protein) (Ropp 120).

SRRM2_HUMAN
NC score	0.056483 (rank : 19)	θ value	0.21417 (rank : 19)
Query Neighborhood Hits	82	Target Neighborhood Hits	1296	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

ATRX_HUMAN
NC score	0.054358 (rank : 20)	θ value	6.88961 (rank : 66)
Query Neighborhood Hits	82	Target Neighborhood Hits	842	Shared Neighborhood Hits	28
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

CJ078_MOUSE
NC score	0.054243 (rank : 21)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	82	Target Neighborhood Hits	559	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

SYBU_MOUSE
NC score	0.053173 (rank : 22)	θ value	0.125558 (rank : 18)
Query Neighborhood Hits	82	Target Neighborhood Hits	214	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHS8, Q3TQN7, Q401F3, Q401F4, Q571C1, Q6P1J2, Q80XH0, Q8BHS7, Q8BI27	Gene names	Sybu, Golsyn, Kiaa1472
Domain Architecture	No domain graphic available
Description	Syntabulin (Syntaxin-1-binding protein) (Golgi-localized syntaphilin- related protein) (m-Golsyn).

SRRM2_MOUSE
NC score	0.052339 (rank : 23)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	82	Target Neighborhood Hits	1470	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

LEO1_HUMAN
NC score	0.051922 (rank : 24)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	82	Target Neighborhood Hits	958	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

ACINU_HUMAN
NC score	0.051827 (rank : 25)	θ value	0.813845 (rank : 24)
Query Neighborhood Hits	82	Target Neighborhood Hits	828	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

MAP1B_HUMAN
NC score	0.050403 (rank : 26)	θ value	3.0926 (rank : 47)
Query Neighborhood Hits	82	Target Neighborhood Hits	903	Shared Neighborhood Hits	32
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MAP1B_MOUSE
NC score	0.050128 (rank : 27)	θ value	2.36792 (rank : 41)
Query Neighborhood Hits	82	Target Neighborhood Hits	977	Shared Neighborhood Hits	29
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

CENPC_HUMAN
NC score	0.050109 (rank : 28)	θ value	0.62314 (rank : 22)
Query Neighborhood Hits	82	Target Neighborhood Hits	147	Shared Neighborhood Hits	11
SwissProt Accessions	Q03188, Q9P0M5	Gene names	CENPC1, CENPC, ICEN7
Domain Architecture	No domain graphic available
Description	Centromere protein C 1 (CENP-C) (Centromere autoantigen C) (Interphase centromere complex protein 7).

CENPR_MOUSE
NC score	0.044255 (rank : 29)	θ value	1.81305 (rank : 32)
Query Neighborhood Hits	82	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CQ82, Q3TLR0, Q3TNR4	Gene names	Itgb3bp, Cenpr, Nrif3
Domain Architecture	No domain graphic available
Description	Centromere protein R (CENP-R) (Nuclear receptor-interacting factor 3).

M2GD_MOUSE
NC score	0.043782 (rank : 30)	θ value	1.81305 (rank : 33)
Query Neighborhood Hits	82	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBT9, Q8R1S7	Gene names	Dmgdh
Domain Architecture
Description	Dimethylglycine dehydrogenase, mitochondrial precursor (EC 1.5.99.2) (ME2GLYDH).

RIOK2_MOUSE
NC score	0.043008 (rank : 31)	θ value	0.813845 (rank : 26)
Query Neighborhood Hits	82	Target Neighborhood Hits	82	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CQS5, Q91XF3	Gene names	Riok2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2).

RN169_HUMAN
NC score	0.041703 (rank : 32)	θ value	1.38821 (rank : 29)
Query Neighborhood Hits	82	Target Neighborhood Hits	203	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

M2GD_HUMAN
NC score	0.041408 (rank : 33)	θ value	2.36792 (rank : 39)
Query Neighborhood Hits	82	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UI17	Gene names	DMGDH
Domain Architecture
Description	Dimethylglycine dehydrogenase, mitochondrial precursor (EC 1.5.99.2) (ME2GLYDH).

SDPR_HUMAN
NC score	0.040360 (rank : 34)	θ value	0.47712 (rank : 21)
Query Neighborhood Hits	82	Target Neighborhood Hits	337	Shared Neighborhood Hits	14
SwissProt Accessions	O95810	Gene names	SDPR
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein) (PS-p68).

BCL7A_HUMAN
NC score	0.039421 (rank : 35)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	82	Target Neighborhood Hits	35	Shared Neighborhood Hits	5
SwissProt Accessions	Q4VC05, Q13843	Gene names	BCL7A
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member A.

APC_HUMAN
NC score	0.039098 (rank : 36)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	82	Target Neighborhood Hits	603	Shared Neighborhood Hits	18
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

BRPF1_HUMAN
NC score	0.034906 (rank : 37)	θ value	1.81305 (rank : 31)
Query Neighborhood Hits	82	Target Neighborhood Hits	259	Shared Neighborhood Hits	11
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

BCL7A_MOUSE
NC score	0.034799 (rank : 38)	θ value	4.03905 (rank : 49)
Query Neighborhood Hits	82	Target Neighborhood Hits	74	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CXE2, Q8C361, Q8C8M8, Q8VD15	Gene names	Bcl7a
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member A.

AP3B1_MOUSE
NC score	0.034107 (rank : 39)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	82	Target Neighborhood Hits	302	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

AP3B1_HUMAN
NC score	0.034027 (rank : 40)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	82	Target Neighborhood Hits	283	Shared Neighborhood Hits	19
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

NU153_HUMAN
NC score	0.033847 (rank : 41)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	82	Target Neighborhood Hits	227	Shared Neighborhood Hits	12
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

CS021_MOUSE
NC score	0.031148 (rank : 42)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	82	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D279, Q3UI04	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf21 homolog.

NKTR_HUMAN
NC score	0.030172 (rank : 43)	θ value	5.27518 (rank : 63)
Query Neighborhood Hits	82	Target Neighborhood Hits	658	Shared Neighborhood Hits	32
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

RSRC1_HUMAN
NC score	0.029661 (rank : 44)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	82	Target Neighborhood Hits	108	Shared Neighborhood Hits	7
SwissProt Accessions	Q96IZ7, Q96QK2, Q9NZE5	Gene names	RSRC1
Domain Architecture	No domain graphic available
Description	Arginine/serine-rich coiled coil protein 1.

AFF2_MOUSE
NC score	0.025392 (rank : 45)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	82	Target Neighborhood Hits	225	Shared Neighborhood Hits	14
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

RRP44_HUMAN
NC score	0.025017 (rank : 46)	θ value	5.27518 (rank : 64)
Query Neighborhood Hits	82	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2L1, Q5W0P7, Q5W0P8, Q658Z7, Q7Z481, Q8WWI2, Q9UG36	Gene names	DIS3, KIAA1008, RRP44
Domain Architecture
Description	Exosome complex exonuclease RRP44 (EC 3.1.13.-) (Ribosomal RNA- processing protein 44) (DIS3 protein homolog).

BRD2_HUMAN
NC score	0.024912 (rank : 47)	θ value	1.81305 (rank : 30)
Query Neighborhood Hits	82	Target Neighborhood Hits	242	Shared Neighborhood Hits	15
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

CENPU_HUMAN
NC score	0.024807 (rank : 48)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	82	Target Neighborhood Hits	289	Shared Neighborhood Hits	14
SwissProt Accessions	Q71F23, Q32Q71, Q9H5G1	Gene names	MLF1IP, CENPU, ICEN24, KLIP1
Domain Architecture	No domain graphic available
Description	Centromere protein U (CENP-U) (CENP-U(50)) (CENP-50) (Interphase centromere complex protein 24) (MLF1-interacting protein) (KSHV latent nuclear antigen-interacting protein 1).

SFR12_HUMAN
NC score	0.023634 (rank : 49)	θ value	8.99809 (rank : 82)
Query Neighborhood Hits	82	Target Neighborhood Hits	553	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

HRX_HUMAN
NC score	0.023586 (rank : 50)	θ value	3.0926 (rank : 46)
Query Neighborhood Hits	82	Target Neighborhood Hits	825	Shared Neighborhood Hits	21
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

WRN_MOUSE
NC score	0.023482 (rank : 51)	θ value	1.81305 (rank : 35)
Query Neighborhood Hits	82	Target Neighborhood Hits	295	Shared Neighborhood Hits	10
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

ABRA_HUMAN
NC score	0.022549 (rank : 52)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	82	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N0Z2	Gene names	ABRA
Domain Architecture	No domain graphic available
Description	Actin-binding Rho-activating protein (Striated muscle activator of Rho-dependent signaling) (STARS).

CE110_MOUSE
NC score	0.022079 (rank : 53)	θ value	4.03905 (rank : 51)
Query Neighborhood Hits	82	Target Neighborhood Hits	170	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TSH4, Q6A072	Gene names	Cep110, Cp110, Kiaa0419
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 110 kDa (Cep110 protein).

BSN_MOUSE
NC score	0.021707 (rank : 54)	θ value	4.03905 (rank : 50)
Query Neighborhood Hits	82	Target Neighborhood Hits	2057	Shared Neighborhood Hits	32
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

ZN318_MOUSE
NC score	0.021023 (rank : 55)	θ value	6.88961 (rank : 71)
Query Neighborhood Hits	82	Target Neighborhood Hits	642	Shared Neighborhood Hits	19
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

BRPF3_HUMAN
NC score	0.020916 (rank : 56)	θ value	5.27518 (rank : 57)
Query Neighborhood Hits	82	Target Neighborhood Hits	217	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

MAP4_MOUSE
NC score	0.018731 (rank : 57)	θ value	8.99809 (rank : 80)
Query Neighborhood Hits	82	Target Neighborhood Hits	409	Shared Neighborhood Hits	16
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

DCR1A_HUMAN
NC score	0.018322 (rank : 58)	θ value	5.27518 (rank : 58)
Query Neighborhood Hits	82	Target Neighborhood Hits	43	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PJP8, Q14701, Q6P5Y3, Q6PKL4	Gene names	DCLRE1A, KIAA0086, SNM1, SNM1A
Domain Architecture	No domain graphic available
Description	DNA cross-link repair 1A protein (hSNM1) (hSNM1A).

MYCB2_MOUSE
NC score	0.018221 (rank : 59)	θ value	4.03905 (rank : 54)
Query Neighborhood Hits	82	Target Neighborhood Hits	307	Shared Neighborhood Hits	9
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

EP15R_MOUSE
NC score	0.017576 (rank : 60)	θ value	1.06291 (rank : 27)
Query Neighborhood Hits	82	Target Neighborhood Hits	1135	Shared Neighborhood Hits	18
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

DDX20_MOUSE
NC score	0.017088 (rank : 61)	θ value	0.62314 (rank : 23)
Query Neighborhood Hits	82	Target Neighborhood Hits	177	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

BRWD1_MOUSE
NC score	0.016546 (rank : 62)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	82	Target Neighborhood Hits	478	Shared Neighborhood Hits	17
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

PALB2_MOUSE
NC score	0.016435 (rank : 63)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	82	Target Neighborhood Hits	133	Shared Neighborhood Hits	5
SwissProt Accessions	Q3U0P1, Q6NZG9, Q7TMQ4, Q8CEA9	Gene names	Palb2
Domain Architecture	No domain graphic available
Description	Partner and localizer of BRCA2.

GP112_HUMAN
NC score	0.015486 (rank : 64)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	82	Target Neighborhood Hits	441	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

FACD2_HUMAN
NC score	0.014255 (rank : 65)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	82	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BXW9, Q2LA86, Q69YP9, Q6PJN7, Q9BQ06, Q9H9T9	Gene names	FANCD2
Domain Architecture	No domain graphic available
Description	Fanconi anemia group D2 protein (Protein FACD2).

DMXL1_HUMAN
NC score	0.014054 (rank : 66)	θ value	4.03905 (rank : 52)
Query Neighborhood Hits	82	Target Neighborhood Hits	259	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y485	Gene names	DMXL1, XL1
Domain Architecture	No domain graphic available
Description	Protein DmX-like 1 (X-like 1 protein).

CA026_HUMAN
NC score	0.013747 (rank : 67)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	82	Target Neighborhood Hits	87	Shared Neighborhood Hits	5
SwissProt Accessions	Q5T5J6, Q8NEK9, Q9BZQ7, Q9NXQ0	Gene names	C1orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf26.

TSH2_HUMAN
NC score	0.013701 (rank : 68)	θ value	6.88961 (rank : 70)
Query Neighborhood Hits	82	Target Neighborhood Hits	479	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NRE2, Q4VXM4, Q6N003, Q8N260	Gene names	TSHZ2, C20orf17, TSH2, ZNF218
Domain Architecture	No domain graphic available
Description	Teashirt homolog 2 (Zinc finger protein 218) (Ovarian cancer-related protein 10-2) (OVC10-2).

LIPA4_HUMAN
NC score	0.013500 (rank : 69)	θ value	4.03905 (rank : 53)
Query Neighborhood Hits	82	Target Neighborhood Hits	56	Shared Neighborhood Hits	2
SwissProt Accessions	O75335, O94971	Gene names	PPFIA4, KIAA0897
Domain Architecture
Description	Liprin-alpha-4 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-4) (PTPRF-interacting protein alpha-4).

GOGA3_HUMAN
NC score	0.012239 (rank : 70)	θ value	0.813845 (rank : 25)
Query Neighborhood Hits	82	Target Neighborhood Hits	1317	Shared Neighborhood Hits	14
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

IP3KB_HUMAN
NC score	0.012178 (rank : 71)	θ value	8.99809 (rank : 78)
Query Neighborhood Hits	82	Target Neighborhood Hits	124	Shared Neighborhood Hits	6
SwissProt Accessions	P27987, Q5VWL9, Q5VWM0, Q96BZ2, Q96JS1, Q9UH47	Gene names	ITPKB
Domain Architecture
Description	Inositol-trisphosphate 3-kinase B (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase B) (IP3K B) (IP3 3-kinase B) (IP3K-B).

PRDM2_HUMAN
NC score	0.011357 (rank : 72)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	82	Target Neighborhood Hits	1135	Shared Neighborhood Hits	15
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

DHX9_MOUSE
NC score	0.011189 (rank : 73)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	82	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	O70133, O35931, O54703, Q5FWY1, Q6R5F7, Q9CSA2	Gene names	Dhx9, Ddx9
Domain Architecture
Description	ATP-dependent RNA helicase A (EC 3.6.1.-) (Nuclear DNA helicase II) (NDH II) (DEAH box protein 9) (mHEL-5).

INCE_MOUSE
NC score	0.011008 (rank : 74)	θ value	5.27518 (rank : 60)
Query Neighborhood Hits	82	Target Neighborhood Hits	903	Shared Neighborhood Hits	14
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

IRK14_HUMAN
NC score	0.010145 (rank : 75)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	82	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UNX9	Gene names	KCNJ14
Domain Architecture	No domain graphic available
Description	ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4).

MYPT1_MOUSE
NC score	0.007432 (rank : 76)	θ value	6.88961 (rank : 67)
Query Neighborhood Hits	82	Target Neighborhood Hits	539	Shared Neighborhood Hits	12
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

KSR1_MOUSE
NC score	0.006625 (rank : 77)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	82	Target Neighborhood Hits	870	Shared Neighborhood Hits	6
SwissProt Accessions	Q61097, Q61648, Q78DX8	Gene names	Ksr1, Ksr
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras) (mKSR1) (Hb protein).

CSPG2_MOUSE
NC score	0.005875 (rank : 78)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	82	Target Neighborhood Hits	711	Shared Neighborhood Hits	9
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

MRP4_HUMAN
NC score	0.005780 (rank : 79)	θ value	5.27518 (rank : 62)
Query Neighborhood Hits	82	Target Neighborhood Hits	107	Shared Neighborhood Hits	2
SwissProt Accessions	O15439, Q9Y6J2	Gene names	ABCC4, MRP4
Domain Architecture
Description	Multidrug resistance-associated protein 4 (ATP-binding cassette sub- family C member 4) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter-B) (MOAT-B).

SDK1_MOUSE
NC score	0.001718 (rank : 80)	θ value	8.99809 (rank : 81)
Query Neighborhood Hits	82	Target Neighborhood Hits	495	Shared Neighborhood Hits	4
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

MAK_HUMAN
NC score	0.001537 (rank : 81)	θ value	2.36792 (rank : 40)
Query Neighborhood Hits	82	Target Neighborhood Hits	857	Shared Neighborhood Hits	3
SwissProt Accessions	P20794, Q9NUH7	Gene names	MAK
Domain Architecture
Description	Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male germ cell- associated kinase).

IRAK3_MOUSE
NC score	0.001532 (rank : 82)	θ value	8.99809 (rank : 79)
Query Neighborhood Hits	82	Target Neighborhood Hits	628	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K4B2, Q8C7U8, Q8CE40, Q8K1S8	Gene names	Irak3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

GLI2_HUMAN
NC score	0.001368 (rank : 83)	θ value	5.27518 (rank : 59)
Query Neighborhood Hits	82	Target Neighborhood Hits	971	Shared Neighborhood Hits	10
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).