Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : CS021_MOUSE

For an explanation of this page, click here

CS021_MOUSE
SwissProt Accessions	Q9D279, Q3UI04	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf21 homolog.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CS021_HUMAN
θ value	0 (rank : 1)	NC score	0.948204 (rank : 2)
Query Neighborhood Hits	47	Target Neighborhood Hits	98	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IVT2	Gene names	C19orf21
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf21.

CS021_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	47	Target Neighborhood Hits	47	Shared Neighborhood Hits	47
SwissProt Accessions	Q9D279, Q3UI04	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf21 homolog.

AKAP2_HUMAN
θ value	0.000602161 (rank : 3)	NC score	0.137708 (rank : 3)
Query Neighborhood Hits	47	Target Neighborhood Hits	507	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

NIPBL_HUMAN
θ value	0.0736092 (rank : 4)	NC score	0.037837 (rank : 12)
Query Neighborhood Hits	47	Target Neighborhood Hits	1311	Shared Neighborhood Hits	16
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

ASPP2_HUMAN
θ value	0.0961366 (rank : 5)	NC score	0.031093 (rank : 19)
Query Neighborhood Hits	47	Target Neighborhood Hits	1156	Shared Neighborhood Hits	10
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

RIN3_HUMAN
θ value	0.125558 (rank : 6)	NC score	0.059075 (rank : 6)
Query Neighborhood Hits	47	Target Neighborhood Hits	227	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

RP1L1_MOUSE
θ value	0.125558 (rank : 7)	NC score	0.058340 (rank : 7)
Query Neighborhood Hits	47	Target Neighborhood Hits	170	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CGM2, Q8K0I4	Gene names	Rp1l1, Rp1hl1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1).

HAX1_HUMAN
θ value	0.365318 (rank : 8)	NC score	0.066636 (rank : 5)
Query Neighborhood Hits	47	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	O00165, Q96AU4, Q9BS80	Gene names	HAX1, HS1BP1
Domain Architecture	No domain graphic available
Description	HS1-associating protein X-1 (HAX-1) (HS1-binding protein).

PYR1_HUMAN
θ value	0.813845 (rank : 9)	NC score	0.034481 (rank : 17)
Query Neighborhood Hits	47	Target Neighborhood Hits	119	Shared Neighborhood Hits	2
SwissProt Accessions	P27708, Q6P0Q0	Gene names	CAD
Domain Architecture	No domain graphic available
Description	CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)].

BTBD7_HUMAN
θ value	1.06291 (rank : 10)	NC score	0.036220 (rank : 15)
Query Neighborhood Hits	47	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	Q9P203, Q69Z05, Q7Z308, Q86TS0, Q9HAA4, Q9NVM0	Gene names	BTBD7, KIAA1525
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 7.

MLL3_HUMAN
θ value	1.06291 (rank : 11)	NC score	0.034651 (rank : 16)
Query Neighborhood Hits	47	Target Neighborhood Hits	1644	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PINX1_MOUSE
θ value	1.06291 (rank : 12)	NC score	0.052765 (rank : 8)
Query Neighborhood Hits	47	Target Neighborhood Hits	64	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CZX5, Q91WZ9, Q9D0C2	Gene names	Pinx1, Lpts
Domain Architecture
Description	Pin2-interacting protein X1 (TRF1-interacting protein 1) (Liver- related putative tumor suppressor) (LPTS1) (67-11-3 protein).

SGIP1_MOUSE
θ value	1.06291 (rank : 13)	NC score	0.044247 (rank : 9)
Query Neighborhood Hits	47	Target Neighborhood Hits	180	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

CCNK_MOUSE
θ value	1.38821 (rank : 14)	NC score	0.030316 (rank : 20)
Query Neighborhood Hits	47	Target Neighborhood Hits	350	Shared Neighborhood Hits	6
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

K1802_HUMAN
θ value	1.38821 (rank : 15)	NC score	0.018851 (rank : 27)
Query Neighborhood Hits	47	Target Neighborhood Hits	1378	Shared Neighborhood Hits	13
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

NOTC3_HUMAN
θ value	1.38821 (rank : 16)	NC score	0.013059 (rank : 33)
Query Neighborhood Hits	47	Target Neighborhood Hits	1062	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_MOUSE
θ value	1.38821 (rank : 17)	NC score	0.012948 (rank : 34)
Query Neighborhood Hits	47	Target Neighborhood Hits	975	Shared Neighborhood Hits	6
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

ZBT40_HUMAN
θ value	1.38821 (rank : 18)	NC score	0.003785 (rank : 47)
Query Neighborhood Hits	47	Target Neighborhood Hits	949	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NUA8, O75066, Q5TFU5, Q8N1R1	Gene names	ZBTB40, KIAA0478
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 40.

MLL3_MOUSE
θ value	1.81305 (rank : 19)	NC score	0.037301 (rank : 13)
Query Neighborhood Hits	47	Target Neighborhood Hits	1399	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

S29A1_HUMAN
θ value	1.81305 (rank : 20)	NC score	0.028889 (rank : 22)
Query Neighborhood Hits	47	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q99808, Q9UJY2	Gene names	SLC29A1, ENT1
Domain Architecture
Description	Equilibrative nucleoside transporter 1 (Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter) (Equilibrative NBMPR-sensitive nucleoside transporter) (Nucleoside transporter, es-type) (Solute carrier family 29 member 1).

USBP1_MOUSE
θ value	1.81305 (rank : 21)	NC score	0.036899 (rank : 14)
Query Neighborhood Hits	47	Target Neighborhood Hits	115	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R370	Gene names	Ushbp1
Domain Architecture	No domain graphic available
Description	USH1C-binding protein 1 (Usher syndrome type-1C protein-binding protein 1).

AAK1_HUMAN
θ value	2.36792 (rank : 22)	NC score	0.009031 (rank : 42)
Query Neighborhood Hits	47	Target Neighborhood Hits	1077	Shared Neighborhood Hits	8
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

AFAD_HUMAN
θ value	2.36792 (rank : 23)	NC score	0.023252 (rank : 23)
Query Neighborhood Hits	47	Target Neighborhood Hits	689	Shared Neighborhood Hits	7
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

BRCA2_HUMAN
θ value	2.36792 (rank : 24)	NC score	0.029876 (rank : 21)
Query Neighborhood Hits	47	Target Neighborhood Hits	202	Shared Neighborhood Hits	5
SwissProt Accessions	P51587, O00183, O15008, Q13879	Gene names	BRCA2, FANCD1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein).

CX021_MOUSE
θ value	2.36792 (rank : 25)	NC score	0.038466 (rank : 11)
Query Neighborhood Hits	47	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D3J9	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein CXorf21 homolog.

EXO1_HUMAN
θ value	2.36792 (rank : 26)	NC score	0.031148 (rank : 18)
Query Neighborhood Hits	47	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UQ84, O60545, O75214, O75466, Q5T396, Q96IJ1, Q9UG38, Q9UNW0	Gene names	EXO1, EXOI, HEX1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (hExo1) (Exonuclease I) (hExoI).

DUT_HUMAN
θ value	4.03905 (rank : 27)	NC score	0.041128 (rank : 10)
Query Neighborhood Hits	47	Target Neighborhood Hits	52	Shared Neighborhood Hits	2
SwissProt Accessions	P33316, O14785, Q16708, Q16860, Q96Q81	Gene names	DUT
Domain Architecture
Description	Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial precursor (EC 3.6.1.23) (dUTPase) (dUTP pyrophosphatase).

MY18B_HUMAN
θ value	4.03905 (rank : 28)	NC score	0.008180 (rank : 43)
Query Neighborhood Hits	47	Target Neighborhood Hits	1299	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

RPGR1_HUMAN
θ value	4.03905 (rank : 29)	NC score	0.015082 (rank : 31)
Query Neighborhood Hits	47	Target Neighborhood Hits	578	Shared Neighborhood Hits	4
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

RTN1_HUMAN
θ value	4.03905 (rank : 30)	NC score	0.020145 (rank : 26)
Query Neighborhood Hits	47	Target Neighborhood Hits	173	Shared Neighborhood Hits	6
SwissProt Accessions	Q16799, Q16800, Q16801	Gene names	RTN1, NSP
Domain Architecture
Description	Reticulon-1 (Neuroendocrine-specific protein).

AATK_MOUSE
θ value	5.27518 (rank : 31)	NC score	0.004351 (rank : 45)
Query Neighborhood Hits	47	Target Neighborhood Hits	942	Shared Neighborhood Hits	7
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

DISC1_HUMAN
θ value	5.27518 (rank : 32)	NC score	0.020456 (rank : 25)
Query Neighborhood Hits	47	Target Neighborhood Hits	199	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NRI5, O75045, Q5VT44, Q5VT45, Q8IXJ0, Q8IXJ1, Q9BX19, Q9NRI3, Q9NRI4	Gene names	DISC1, KIAA0457
Domain Architecture	No domain graphic available
Description	Disrupted in schizophrenia 1 protein.

BIN1_HUMAN
θ value	6.88961 (rank : 33)	NC score	0.017004 (rank : 29)
Query Neighborhood Hits	47	Target Neighborhood Hits	335	Shared Neighborhood Hits	7
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

GCDH_HUMAN
θ value	6.88961 (rank : 34)	NC score	0.011641 (rank : 36)
Query Neighborhood Hits	47	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q92947, O14719	Gene names	GCDH
Domain Architecture
Description	Glutaryl-CoA dehydrogenase, mitochondrial precursor (EC 1.3.99.7) (GCD).

IQEC3_HUMAN
θ value	6.88961 (rank : 35)	NC score	0.017048 (rank : 28)
Query Neighborhood Hits	47	Target Neighborhood Hits	125	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UPP2, Q8TB43	Gene names	IQSEC3, KIAA1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

RFIP1_HUMAN
θ value	6.88961 (rank : 36)	NC score	0.016049 (rank : 30)
Query Neighborhood Hits	47	Target Neighborhood Hits	236	Shared Neighborhood Hits	6
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

RPGF3_HUMAN
θ value	6.88961 (rank : 37)	NC score	0.010847 (rank : 38)
Query Neighborhood Hits	47	Target Neighborhood Hits	56	Shared Neighborhood Hits	2
SwissProt Accessions	O95398, O95634, Q8WVN0	Gene names	RAPGEF3, CGEF1, EPAC, EPAC1
Domain Architecture
Description	Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1) (Rap1 guanine-nucleotide-exchange factor directly activated by cAMP).

SIA8E_MOUSE
θ value	6.88961 (rank : 38)	NC score	0.011272 (rank : 37)
Query Neighborhood Hits	47	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	P70126, P70127, P70128	Gene names	St8sia5, Siat8e, St8siav
Domain Architecture
Description	Alpha-2,8-sialyltransferase 8E (EC 2.4.99.-) (ST8Sia V).

COCA1_MOUSE
θ value	8.99809 (rank : 39)	NC score	0.006998 (rank : 44)
Query Neighborhood Hits	47	Target Neighborhood Hits	467	Shared Neighborhood Hits	7
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

DTNB_MOUSE
θ value	8.99809 (rank : 40)	NC score	0.010100 (rank : 40)
Query Neighborhood Hits	47	Target Neighborhood Hits	263	Shared Neighborhood Hits	4
SwissProt Accessions	O70585, O70563, Q9CTZ1	Gene names	Dtnb
Domain Architecture
Description	Dystrobrevin beta (Beta-dystrobrevin) (DTN-B) (MDTN-B).

G7D_MOUSE
θ value	8.99809 (rank : 41)	NC score	0.022092 (rank : 24)
Query Neighborhood Hits	47	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CY86, Q9Z1Q7	Gene names	Ng23, G7d
Domain Architecture	No domain graphic available
Description	Protein G7d.

KKCC1_MOUSE
θ value	8.99809 (rank : 42)	NC score	0.004194 (rank : 46)
Query Neighborhood Hits	47	Target Neighborhood Hits	866	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VBY2, Q9R054	Gene names	Camkk1, Camkk
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase kinase 1 (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinase kinase alpha) (CaM-KK alpha) (CaMKK alpha) (CaMKK 1) (CaM-kinase IV kinase).

ORC1_HUMAN
θ value	8.99809 (rank : 43)	NC score	0.013660 (rank : 32)
Query Neighborhood Hits	47	Target Neighborhood Hits	102	Shared Neighborhood Hits	2
SwissProt Accessions	Q13415, Q13471, Q5T0F5	Gene names	ORC1L, ORC1, PARC1
Domain Architecture
Description	Origin recognition complex subunit 1 (Replication control protein 1).

PO6F2_MOUSE
θ value	8.99809 (rank : 44)	NC score	0.009599 (rank : 41)
Query Neighborhood Hits	47	Target Neighborhood Hits	639	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

PTPRD_MOUSE
θ value	8.99809 (rank : 45)	NC score	0.002727 (rank : 48)
Query Neighborhood Hits	47	Target Neighborhood Hits	491	Shared Neighborhood Hits	3
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

SATB1_HUMAN
θ value	8.99809 (rank : 46)	NC score	0.012334 (rank : 35)
Query Neighborhood Hits	47	Target Neighborhood Hits	130	Shared Neighborhood Hits	5
SwissProt Accessions	Q01826	Gene names	SATB1
Domain Architecture
Description	DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1).

TOP2A_HUMAN
θ value	8.99809 (rank : 47)	NC score	0.010791 (rank : 39)
Query Neighborhood Hits	47	Target Neighborhood Hits	135	Shared Neighborhood Hits	3
SwissProt Accessions	P11388, Q71UN1, Q9HB24, Q9HB25, Q9HB26, Q9UP44, Q9UQP9	Gene names	TOP2A, TOP2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

AKAP2_MOUSE
θ value	θ > 10 (rank : 48)	NC score	0.081758 (rank : 4)
Query Neighborhood Hits	47	Target Neighborhood Hits	385	Shared Neighborhood Hits	4
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

Hits sorted by NC score

CS021_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	47	Target Neighborhood Hits	47	Shared Neighborhood Hits	47
SwissProt Accessions	Q9D279, Q3UI04	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf21 homolog.

CS021_HUMAN
NC score	0.948204 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	47	Target Neighborhood Hits	98	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IVT2	Gene names	C19orf21
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf21.

AKAP2_HUMAN
NC score	0.137708 (rank : 3)	θ value	0.000602161 (rank : 3)
Query Neighborhood Hits	47	Target Neighborhood Hits	507	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

AKAP2_MOUSE
NC score	0.081758 (rank : 4)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	47	Target Neighborhood Hits	385	Shared Neighborhood Hits	4
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

HAX1_HUMAN
NC score	0.066636 (rank : 5)	θ value	0.365318 (rank : 8)
Query Neighborhood Hits	47	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	O00165, Q96AU4, Q9BS80	Gene names	HAX1, HS1BP1
Domain Architecture	No domain graphic available
Description	HS1-associating protein X-1 (HAX-1) (HS1-binding protein).

RIN3_HUMAN
NC score	0.059075 (rank : 6)	θ value	0.125558 (rank : 6)
Query Neighborhood Hits	47	Target Neighborhood Hits	227	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

RP1L1_MOUSE
NC score	0.058340 (rank : 7)	θ value	0.125558 (rank : 7)
Query Neighborhood Hits	47	Target Neighborhood Hits	170	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CGM2, Q8K0I4	Gene names	Rp1l1, Rp1hl1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1).

PINX1_MOUSE
NC score	0.052765 (rank : 8)	θ value	1.06291 (rank : 12)
Query Neighborhood Hits	47	Target Neighborhood Hits	64	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CZX5, Q91WZ9, Q9D0C2	Gene names	Pinx1, Lpts
Domain Architecture
Description	Pin2-interacting protein X1 (TRF1-interacting protein 1) (Liver- related putative tumor suppressor) (LPTS1) (67-11-3 protein).

SGIP1_MOUSE
NC score	0.044247 (rank : 9)	θ value	1.06291 (rank : 13)
Query Neighborhood Hits	47	Target Neighborhood Hits	180	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

DUT_HUMAN
NC score	0.041128 (rank : 10)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	47	Target Neighborhood Hits	52	Shared Neighborhood Hits	2
SwissProt Accessions	P33316, O14785, Q16708, Q16860, Q96Q81	Gene names	DUT
Domain Architecture
Description	Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial precursor (EC 3.6.1.23) (dUTPase) (dUTP pyrophosphatase).

CX021_MOUSE
NC score	0.038466 (rank : 11)	θ value	2.36792 (rank : 25)
Query Neighborhood Hits	47	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D3J9	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein CXorf21 homolog.

NIPBL_HUMAN
NC score	0.037837 (rank : 12)	θ value	0.0736092 (rank : 4)
Query Neighborhood Hits	47	Target Neighborhood Hits	1311	Shared Neighborhood Hits	16
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

MLL3_MOUSE
NC score	0.037301 (rank : 13)	θ value	1.81305 (rank : 19)
Query Neighborhood Hits	47	Target Neighborhood Hits	1399	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

USBP1_MOUSE
NC score	0.036899 (rank : 14)	θ value	1.81305 (rank : 21)
Query Neighborhood Hits	47	Target Neighborhood Hits	115	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R370	Gene names	Ushbp1
Domain Architecture	No domain graphic available
Description	USH1C-binding protein 1 (Usher syndrome type-1C protein-binding protein 1).

BTBD7_HUMAN
NC score	0.036220 (rank : 15)	θ value	1.06291 (rank : 10)
Query Neighborhood Hits	47	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	Q9P203, Q69Z05, Q7Z308, Q86TS0, Q9HAA4, Q9NVM0	Gene names	BTBD7, KIAA1525
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 7.

MLL3_HUMAN
NC score	0.034651 (rank : 16)	θ value	1.06291 (rank : 11)
Query Neighborhood Hits	47	Target Neighborhood Hits	1644	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PYR1_HUMAN
NC score	0.034481 (rank : 17)	θ value	0.813845 (rank : 9)
Query Neighborhood Hits	47	Target Neighborhood Hits	119	Shared Neighborhood Hits	2
SwissProt Accessions	P27708, Q6P0Q0	Gene names	CAD
Domain Architecture	No domain graphic available
Description	CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)].

EXO1_HUMAN
NC score	0.031148 (rank : 18)	θ value	2.36792 (rank : 26)
Query Neighborhood Hits	47	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UQ84, O60545, O75214, O75466, Q5T396, Q96IJ1, Q9UG38, Q9UNW0	Gene names	EXO1, EXOI, HEX1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (hExo1) (Exonuclease I) (hExoI).

ASPP2_HUMAN
NC score	0.031093 (rank : 19)	θ value	0.0961366 (rank : 5)
Query Neighborhood Hits	47	Target Neighborhood Hits	1156	Shared Neighborhood Hits	10
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

CCNK_MOUSE
NC score	0.030316 (rank : 20)	θ value	1.38821 (rank : 14)
Query Neighborhood Hits	47	Target Neighborhood Hits	350	Shared Neighborhood Hits	6
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

BRCA2_HUMAN
NC score	0.029876 (rank : 21)	θ value	2.36792 (rank : 24)
Query Neighborhood Hits	47	Target Neighborhood Hits	202	Shared Neighborhood Hits	5
SwissProt Accessions	P51587, O00183, O15008, Q13879	Gene names	BRCA2, FANCD1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein).

S29A1_HUMAN
NC score	0.028889 (rank : 22)	θ value	1.81305 (rank : 20)
Query Neighborhood Hits	47	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q99808, Q9UJY2	Gene names	SLC29A1, ENT1
Domain Architecture
Description	Equilibrative nucleoside transporter 1 (Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter) (Equilibrative NBMPR-sensitive nucleoside transporter) (Nucleoside transporter, es-type) (Solute carrier family 29 member 1).

AFAD_HUMAN
NC score	0.023252 (rank : 23)	θ value	2.36792 (rank : 23)
Query Neighborhood Hits	47	Target Neighborhood Hits	689	Shared Neighborhood Hits	7
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

G7D_MOUSE
NC score	0.022092 (rank : 24)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	47	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CY86, Q9Z1Q7	Gene names	Ng23, G7d
Domain Architecture	No domain graphic available
Description	Protein G7d.

DISC1_HUMAN
NC score	0.020456 (rank : 25)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	47	Target Neighborhood Hits	199	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NRI5, O75045, Q5VT44, Q5VT45, Q8IXJ0, Q8IXJ1, Q9BX19, Q9NRI3, Q9NRI4	Gene names	DISC1, KIAA0457
Domain Architecture	No domain graphic available
Description	Disrupted in schizophrenia 1 protein.

RTN1_HUMAN
NC score	0.020145 (rank : 26)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	47	Target Neighborhood Hits	173	Shared Neighborhood Hits	6
SwissProt Accessions	Q16799, Q16800, Q16801	Gene names	RTN1, NSP
Domain Architecture
Description	Reticulon-1 (Neuroendocrine-specific protein).

K1802_HUMAN
NC score	0.018851 (rank : 27)	θ value	1.38821 (rank : 15)
Query Neighborhood Hits	47	Target Neighborhood Hits	1378	Shared Neighborhood Hits	13
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

IQEC3_HUMAN
NC score	0.017048 (rank : 28)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	47	Target Neighborhood Hits	125	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UPP2, Q8TB43	Gene names	IQSEC3, KIAA1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

BIN1_HUMAN
NC score	0.017004 (rank : 29)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	47	Target Neighborhood Hits	335	Shared Neighborhood Hits	7
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

RFIP1_HUMAN
NC score	0.016049 (rank : 30)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	47	Target Neighborhood Hits	236	Shared Neighborhood Hits	6
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

RPGR1_HUMAN
NC score	0.015082 (rank : 31)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	47	Target Neighborhood Hits	578	Shared Neighborhood Hits	4
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

ORC1_HUMAN
NC score	0.013660 (rank : 32)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	47	Target Neighborhood Hits	102	Shared Neighborhood Hits	2
SwissProt Accessions	Q13415, Q13471, Q5T0F5	Gene names	ORC1L, ORC1, PARC1
Domain Architecture
Description	Origin recognition complex subunit 1 (Replication control protein 1).

NOTC3_HUMAN
NC score	0.013059 (rank : 33)	θ value	1.38821 (rank : 16)
Query Neighborhood Hits	47	Target Neighborhood Hits	1062	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_MOUSE
NC score	0.012948 (rank : 34)	θ value	1.38821 (rank : 17)
Query Neighborhood Hits	47	Target Neighborhood Hits	975	Shared Neighborhood Hits	6
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

SATB1_HUMAN
NC score	0.012334 (rank : 35)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	47	Target Neighborhood Hits	130	Shared Neighborhood Hits	5
SwissProt Accessions	Q01826	Gene names	SATB1
Domain Architecture
Description	DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1).

GCDH_HUMAN
NC score	0.011641 (rank : 36)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	47	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q92947, O14719	Gene names	GCDH
Domain Architecture
Description	Glutaryl-CoA dehydrogenase, mitochondrial precursor (EC 1.3.99.7) (GCD).

SIA8E_MOUSE
NC score	0.011272 (rank : 37)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	47	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	P70126, P70127, P70128	Gene names	St8sia5, Siat8e, St8siav
Domain Architecture
Description	Alpha-2,8-sialyltransferase 8E (EC 2.4.99.-) (ST8Sia V).

RPGF3_HUMAN
NC score	0.010847 (rank : 38)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	47	Target Neighborhood Hits	56	Shared Neighborhood Hits	2
SwissProt Accessions	O95398, O95634, Q8WVN0	Gene names	RAPGEF3, CGEF1, EPAC, EPAC1
Domain Architecture
Description	Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1) (Rap1 guanine-nucleotide-exchange factor directly activated by cAMP).

TOP2A_HUMAN
NC score	0.010791 (rank : 39)	θ value	8.99809 (rank : 47)
Query Neighborhood Hits	47	Target Neighborhood Hits	135	Shared Neighborhood Hits	3
SwissProt Accessions	P11388, Q71UN1, Q9HB24, Q9HB25, Q9HB26, Q9UP44, Q9UQP9	Gene names	TOP2A, TOP2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

DTNB_MOUSE
NC score	0.010100 (rank : 40)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	47	Target Neighborhood Hits	263	Shared Neighborhood Hits	4
SwissProt Accessions	O70585, O70563, Q9CTZ1	Gene names	Dtnb
Domain Architecture
Description	Dystrobrevin beta (Beta-dystrobrevin) (DTN-B) (MDTN-B).

PO6F2_MOUSE
NC score	0.009599 (rank : 41)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	47	Target Neighborhood Hits	639	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

AAK1_HUMAN
NC score	0.009031 (rank : 42)	θ value	2.36792 (rank : 22)
Query Neighborhood Hits	47	Target Neighborhood Hits	1077	Shared Neighborhood Hits	8
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

MY18B_HUMAN
NC score	0.008180 (rank : 43)	θ value	4.03905 (rank : 28)
Query Neighborhood Hits	47	Target Neighborhood Hits	1299	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

COCA1_MOUSE
NC score	0.006998 (rank : 44)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	47	Target Neighborhood Hits	467	Shared Neighborhood Hits	7
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

AATK_MOUSE
NC score	0.004351 (rank : 45)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	47	Target Neighborhood Hits	942	Shared Neighborhood Hits	7
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

KKCC1_MOUSE
NC score	0.004194 (rank : 46)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	47	Target Neighborhood Hits	866	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VBY2, Q9R054	Gene names	Camkk1, Camkk
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase kinase 1 (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinase kinase alpha) (CaM-KK alpha) (CaMKK alpha) (CaMKK 1) (CaM-kinase IV kinase).

ZBT40_HUMAN
NC score	0.003785 (rank : 47)	θ value	1.38821 (rank : 18)
Query Neighborhood Hits	47	Target Neighborhood Hits	949	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NUA8, O75066, Q5TFU5, Q8N1R1	Gene names	ZBTB40, KIAA0478
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 40.

PTPRD_MOUSE
NC score	0.002727 (rank : 48)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	47	Target Neighborhood Hits	491	Shared Neighborhood Hits	3
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).