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Network neighborhood for query Sequence : TOP2A_HUMAN

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TOP2A_HUMAN
SwissProt Accessions	P11388, Q71UN1, Q9HB24, Q9HB25, Q9HB26, Q9UP44, Q9UQP9	Gene names	TOP2A, TOP2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TOP2A_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	135	Target Neighborhood Hits	135	Shared Neighborhood Hits	135
SwissProt Accessions	P11388, Q71UN1, Q9HB24, Q9HB25, Q9HB26, Q9UP44, Q9UQP9	Gene names	TOP2A, TOP2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

TOP2A_MOUSE
θ value	0 (rank : 2)	NC score	0.972769 (rank : 2)
Query Neighborhood Hits	135	Target Neighborhood Hits	101	Shared Neighborhood Hits	29
SwissProt Accessions	Q01320	Gene names	Top2a, Top-2, Top2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

TOP2B_HUMAN
θ value	0 (rank : 3)	NC score	0.970087 (rank : 4)
Query Neighborhood Hits	135	Target Neighborhood Hits	101	Shared Neighborhood Hits	16
SwissProt Accessions	Q02880, Q13600, Q9UMG8, Q9UQP8	Gene names	TOP2B
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).

TOP2B_MOUSE
θ value	0 (rank : 4)	NC score	0.972292 (rank : 3)
Query Neighborhood Hits	135	Target Neighborhood Hits	80	Shared Neighborhood Hits	21
SwissProt Accessions	Q64511, Q7TQG4	Gene names	Top2b
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).

TXND2_MOUSE
θ value	0.000602161 (rank : 5)	NC score	0.091189 (rank : 7)
Query Neighborhood Hits	135	Target Neighborhood Hits	828	Shared Neighborhood Hits	57
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

TGON2_HUMAN
θ value	0.00869519 (rank : 6)	NC score	0.072634 (rank : 11)
Query Neighborhood Hits	135	Target Neighborhood Hits	1037	Shared Neighborhood Hits	48
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

MINT_MOUSE
θ value	0.0113563 (rank : 7)	NC score	0.049394 (rank : 26)
Query Neighborhood Hits	135	Target Neighborhood Hits	1514	Shared Neighborhood Hits	55
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

IWS1_HUMAN
θ value	0.0148317 (rank : 8)	NC score	0.105387 (rank : 5)
Query Neighborhood Hits	135	Target Neighborhood Hits	1241	Shared Neighborhood Hits	63
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

RFC1_MOUSE
θ value	0.0148317 (rank : 9)	NC score	0.067443 (rank : 14)
Query Neighborhood Hits	135	Target Neighborhood Hits	290	Shared Neighborhood Hits	27
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

IWS1_MOUSE
θ value	0.0431538 (rank : 10)	NC score	0.092623 (rank : 6)
Query Neighborhood Hits	135	Target Neighborhood Hits	1258	Shared Neighborhood Hits	57
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

TTF2_MOUSE
θ value	0.0431538 (rank : 11)	NC score	0.035442 (rank : 45)
Query Neighborhood Hits	135	Target Neighborhood Hits	364	Shared Neighborhood Hits	24
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

K0146_HUMAN
θ value	0.0736092 (rank : 12)	NC score	0.047750 (rank : 28)
Query Neighborhood Hits	135	Target Neighborhood Hits	48	Shared Neighborhood Hits	5
SwissProt Accessions	Q14159, Q96BI5	Gene names	KIAA0146
Domain Architecture	No domain graphic available
Description	Protein KIAA0146.

RN168_MOUSE
θ value	0.0736092 (rank : 13)	NC score	0.042291 (rank : 36)
Query Neighborhood Hits	135	Target Neighborhood Hits	440	Shared Neighborhood Hits	26
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TITIN_HUMAN
θ value	0.0961366 (rank : 14)	NC score	0.014963 (rank : 117)
Query Neighborhood Hits	135	Target Neighborhood Hits	2923	Shared Neighborhood Hits	64
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

HOME1_MOUSE
θ value	0.125558 (rank : 15)	NC score	0.035410 (rank : 46)
Query Neighborhood Hits	135	Target Neighborhood Hits	630	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Z2Y3, Q8K3E1, Q8K4M8, Q9Z0E9, Q9Z216	Gene names	Homer1, Vesl1
Domain Architecture
Description	Homer protein homolog 1 (VASP/Ena-related gene up-regulated during seizure and LTP) (Vesl-1).

GOGA5_MOUSE
θ value	0.163984 (rank : 16)	NC score	0.033304 (rank : 52)
Query Neighborhood Hits	135	Target Neighborhood Hits	1434	Shared Neighborhood Hits	52
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

KMHN1_MOUSE
θ value	0.163984 (rank : 17)	NC score	0.033737 (rank : 51)
Query Neighborhood Hits	135	Target Neighborhood Hits	949	Shared Neighborhood Hits	39
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

LAD1_MOUSE
θ value	0.163984 (rank : 18)	NC score	0.050478 (rank : 25)
Query Neighborhood Hits	135	Target Neighborhood Hits	391	Shared Neighborhood Hits	30
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

STK10_MOUSE
θ value	0.21417 (rank : 19)	NC score	0.014672 (rank : 118)
Query Neighborhood Hits	135	Target Neighborhood Hits	2132	Shared Neighborhood Hits	62
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

BCAS1_HUMAN
θ value	0.279714 (rank : 20)	NC score	0.042996 (rank : 35)
Query Neighborhood Hits	135	Target Neighborhood Hits	133	Shared Neighborhood Hits	10
SwissProt Accessions	O75363, Q68CZ3	Gene names	BCAS1, AIBC1, NABC1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 1 (Novel amplified in breast cancer 1) (Amplified and overexpressed in breast cancer).

LSP1_MOUSE
θ value	0.279714 (rank : 21)	NC score	0.043195 (rank : 34)
Query Neighborhood Hits	135	Target Neighborhood Hits	125	Shared Neighborhood Hits	5
SwissProt Accessions	P19973, P97339, Q04950, Q62022, Q62023, Q62024, Q8CD28, Q99L65	Gene names	Lsp1, Pp52, S37, Wp34
Domain Architecture
Description	Lymphocyte-specific protein 1 (Protein pp52) (52 kDa phosphoprotein) (Lymphocyte-specific antigen WP34) (S37 protein).

R51A1_MOUSE
θ value	0.279714 (rank : 22)	NC score	0.081582 (rank : 8)
Query Neighborhood Hits	135	Target Neighborhood Hits	164	Shared Neighborhood Hits	24
SwissProt Accessions	Q8C551, O55219, Q8BP36, Q99L94, Q9D0J0	Gene names	Rad51ap1
Domain Architecture	No domain graphic available
Description	RAD51-associated protein 1 (RAD51-interacting protein) (RAB22).

TXND2_HUMAN
θ value	0.279714 (rank : 23)	NC score	0.077542 (rank : 9)
Query Neighborhood Hits	135	Target Neighborhood Hits	793	Shared Neighborhood Hits	42
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

AHTF1_HUMAN
θ value	0.365318 (rank : 24)	NC score	0.048152 (rank : 27)
Query Neighborhood Hits	135	Target Neighborhood Hits	286	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WYP5, Q7Z4E3, Q8IZA4, Q96EH9, Q9Y4Q6	Gene names	AHCTF1, ELYS, TMBS62
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

CENPF_HUMAN
θ value	0.365318 (rank : 25)	NC score	0.030872 (rank : 62)
Query Neighborhood Hits	135	Target Neighborhood Hits	1932	Shared Neighborhood Hits	55
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

NKTR_HUMAN
θ value	0.365318 (rank : 26)	NC score	0.039343 (rank : 39)
Query Neighborhood Hits	135	Target Neighborhood Hits	658	Shared Neighborhood Hits	32
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

REST_MOUSE
θ value	0.365318 (rank : 27)	NC score	0.030514 (rank : 63)
Query Neighborhood Hits	135	Target Neighborhood Hits	1506	Shared Neighborhood Hits	56
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

CASP_HUMAN
θ value	0.47712 (rank : 28)	NC score	0.031179 (rank : 59)
Query Neighborhood Hits	135	Target Neighborhood Hits	1131	Shared Neighborhood Hits	47
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CUTL1_HUMAN
θ value	0.47712 (rank : 29)	NC score	0.031253 (rank : 58)
Query Neighborhood Hits	135	Target Neighborhood Hits	1574	Shared Neighborhood Hits	62
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

GOGB1_HUMAN
θ value	0.47712 (rank : 30)	NC score	0.031626 (rank : 56)
Query Neighborhood Hits	135	Target Neighborhood Hits	2297	Shared Neighborhood Hits	67
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

K1C16_HUMAN
θ value	0.47712 (rank : 31)	NC score	0.013967 (rank : 120)
Query Neighborhood Hits	135	Target Neighborhood Hits	440	Shared Neighborhood Hits	26
SwissProt Accessions	P08779, P30654, Q16402, Q9UBG8	Gene names	KRT16, KRT16A
Domain Architecture
Description	Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16).

MDC1_HUMAN
θ value	0.47712 (rank : 32)	NC score	0.035046 (rank : 48)
Query Neighborhood Hits	135	Target Neighborhood Hits	1446	Shared Neighborhood Hits	45
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MYO5C_HUMAN
θ value	0.47712 (rank : 33)	NC score	0.022420 (rank : 86)
Query Neighborhood Hits	135	Target Neighborhood Hits	1206	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

PRC1_HUMAN
θ value	0.47712 (rank : 34)	NC score	0.037262 (rank : 41)
Query Neighborhood Hits	135	Target Neighborhood Hits	328	Shared Neighborhood Hits	24
SwissProt Accessions	O43663, Q9BSB6	Gene names	PRC1
Domain Architecture	No domain graphic available
Description	Protein regulator of cytokinesis 1.

RRBP1_HUMAN
θ value	0.47712 (rank : 35)	NC score	0.062064 (rank : 16)
Query Neighborhood Hits	135	Target Neighborhood Hits	1306	Shared Neighborhood Hits	63
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

TCAL5_HUMAN
θ value	0.47712 (rank : 36)	NC score	0.026946 (rank : 74)
Query Neighborhood Hits	135	Target Neighborhood Hits	806	Shared Neighborhood Hits	35
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

DDX21_MOUSE
θ value	0.62314 (rank : 37)	NC score	0.020834 (rank : 90)
Query Neighborhood Hits	135	Target Neighborhood Hits	350	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

FA47A_HUMAN
θ value	0.62314 (rank : 38)	NC score	0.036929 (rank : 42)
Query Neighborhood Hits	135	Target Neighborhood Hits	451	Shared Neighborhood Hits	17
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

HERC2_HUMAN
θ value	0.62314 (rank : 39)	NC score	0.020384 (rank : 91)
Query Neighborhood Hits	135	Target Neighborhood Hits	163	Shared Neighborhood Hits	6
SwissProt Accessions	O95714, Q86SV7, Q86SV8, Q86SV9, Q86YY3, Q86YY4, Q86YY5, Q86YY6, Q86YY7, Q86YY8, Q86YY9, Q86YZ0, Q86YZ1	Gene names	HERC2
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

LHR2A_HUMAN
θ value	0.62314 (rank : 40)	NC score	0.028585 (rank : 69)
Query Neighborhood Hits	135	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	O00534, Q6UN19, Q6UN20, Q9BVF8	Gene names	LOH11CR2A, BCSC1
Domain Architecture
Description	Loss of heterozygosity 11 chromosomal region 2 gene A protein (Breast cancer suppressor candidate 1) (BCSC-1).

MO4L1_MOUSE
θ value	0.62314 (rank : 41)	NC score	0.032758 (rank : 53)
Query Neighborhood Hits	135	Target Neighborhood Hits	51	Shared Neighborhood Hits	7
SwissProt Accessions	P60762, Q8BNY9, Q99MQ0	Gene names	Morf4l1, Mrg15, Tex189
Domain Architecture
Description	Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (Transcription factor-like protein MRG15) (Testis-expressed gene 189 protein).

SRRM2_MOUSE
θ value	0.62314 (rank : 42)	NC score	0.045552 (rank : 29)
Query Neighborhood Hits	135	Target Neighborhood Hits	1470	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

CD2L5_MOUSE
θ value	0.813845 (rank : 43)	NC score	0.007030 (rank : 133)
Query Neighborhood Hits	135	Target Neighborhood Hits	1011	Shared Neighborhood Hits	24
SwissProt Accessions	Q69ZA1, Q80V11, Q8BZG1, Q8K0A4	Gene names	Cdc2l5, Kiaa1791
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5).

GOGA5_HUMAN
θ value	0.813845 (rank : 44)	NC score	0.031555 (rank : 57)
Query Neighborhood Hits	135	Target Neighborhood Hits	1168	Shared Neighborhood Hits	45
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

KI67_HUMAN
θ value	0.813845 (rank : 45)	NC score	0.058456 (rank : 18)
Query Neighborhood Hits	135	Target Neighborhood Hits	581	Shared Neighborhood Hits	41
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

MO4L1_HUMAN
θ value	0.813845 (rank : 46)	NC score	0.031917 (rank : 55)
Query Neighborhood Hits	135	Target Neighborhood Hits	51	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UBU8, O95899, Q5QTS1, Q6NVX8, Q86YT7, Q9HBP6, Q9NSW5	Gene names	MORF4L1, MRG15
Domain Architecture
Description	Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (Transcription factor-like protein MRG15) (MSL3-1 protein).

MY18A_HUMAN
θ value	0.813845 (rank : 47)	NC score	0.025624 (rank : 80)
Query Neighborhood Hits	135	Target Neighborhood Hits	1929	Shared Neighborhood Hits	60
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

PHLB2_MOUSE
θ value	0.813845 (rank : 48)	NC score	0.031011 (rank : 61)
Query Neighborhood Hits	135	Target Neighborhood Hits	1016	Shared Neighborhood Hits	47
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PIBF1_HUMAN
θ value	0.813845 (rank : 49)	NC score	0.036225 (rank : 43)
Query Neighborhood Hits	135	Target Neighborhood Hits	1041	Shared Neighborhood Hits	47
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

ATRX_MOUSE
θ value	1.06291 (rank : 50)	NC score	0.055050 (rank : 20)
Query Neighborhood Hits	135	Target Neighborhood Hits	682	Shared Neighborhood Hits	59
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

CASC5_HUMAN
θ value	1.06291 (rank : 51)	NC score	0.037692 (rank : 40)
Query Neighborhood Hits	135	Target Neighborhood Hits	376	Shared Neighborhood Hits	28
SwissProt Accessions	Q8NG31, Q8NHE1, Q8WXA6, Q9HCK2, Q9NR92	Gene names	CASC5, KIAA1570
Domain Architecture	No domain graphic available
Description	Protein CASC5 (Cancer susceptibility candidate gene 5 protein) (ALL1- fused gene from chromosome 15q14) (AF15q14) (D40/AF15q14 protein).

CP135_HUMAN
θ value	1.06291 (rank : 52)	NC score	0.031151 (rank : 60)
Query Neighborhood Hits	135	Target Neighborhood Hits	1290	Shared Neighborhood Hits	46
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

MYPT2_HUMAN
θ value	1.06291 (rank : 53)	NC score	0.015693 (rank : 112)
Query Neighborhood Hits	135	Target Neighborhood Hits	707	Shared Neighborhood Hits	37
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

RFC1_HUMAN
θ value	1.06291 (rank : 54)	NC score	0.076740 (rank : 10)
Query Neighborhood Hits	135	Target Neighborhood Hits	352	Shared Neighborhood Hits	34
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

RSF1_HUMAN
θ value	1.06291 (rank : 55)	NC score	0.063319 (rank : 15)
Query Neighborhood Hits	135	Target Neighborhood Hits	539	Shared Neighborhood Hits	53
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

UGGG1_HUMAN
θ value	1.06291 (rank : 56)	NC score	0.028434 (rank : 70)
Query Neighborhood Hits	135	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NYU2, Q8IW30, Q9H8I4	Gene names	UGCGL1, GT, UGGT, UGT1, UGTR
Domain Architecture	No domain graphic available
Description	UDP-glucose:glycoprotein glucosyltransferase 1 precursor (EC 2.4.1.-) (UDP-glucose ceramide glucosyltransferase-like 1) (UDP-- Glc:glycoprotein glucosyltransferase) (HUGT1).

DIDO1_HUMAN
θ value	1.38821 (rank : 57)	NC score	0.023389 (rank : 84)
Query Neighborhood Hits	135	Target Neighborhood Hits	960	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

K0423_HUMAN
θ value	1.38821 (rank : 58)	NC score	0.028689 (rank : 68)
Query Neighborhood Hits	135	Target Neighborhood Hits	171	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y4F4, Q68D66, Q6PG27	Gene names	KIAA0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

MARE1_HUMAN
θ value	1.38821 (rank : 59)	NC score	0.018340 (rank : 101)
Query Neighborhood Hits	135	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q15691	Gene names	MAPRE1
Domain Architecture
Description	Microtubule-associated protein RP/EB family member 1 (APC-binding protein EB1) (End-binding protein 1) (EB1).

PCLO_HUMAN
θ value	1.38821 (rank : 60)	NC score	0.044224 (rank : 30)
Query Neighborhood Hits	135	Target Neighborhood Hits	2046	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SNPC2_HUMAN
θ value	1.38821 (rank : 61)	NC score	0.034044 (rank : 50)
Query Neighborhood Hits	135	Target Neighborhood Hits	56	Shared Neighborhood Hits	9
SwissProt Accessions	Q13487, Q13486	Gene names	SNAPC2, SNAP45
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 2 (SNAPc subunit 2) (snRNA- activating protein complex 45 kDa subunit) (SNAPc 45 kDa subunit) (Small nuclear RNA-activating complex polypeptide 2) (Proximal sequence element-binding transcription factor subunit delta) (PSE- binding factor subunit delta) (PTF subunit delta).

STK10_HUMAN
θ value	1.38821 (rank : 62)	NC score	0.011829 (rank : 123)
Query Neighborhood Hits	135	Target Neighborhood Hits	1921	Shared Neighborhood Hits	49
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

TACC2_MOUSE
θ value	1.38821 (rank : 63)	NC score	0.028080 (rank : 71)
Query Neighborhood Hits	135	Target Neighborhood Hits	774	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

TAOK2_MOUSE
θ value	1.38821 (rank : 64)	NC score	0.017221 (rank : 108)
Query Neighborhood Hits	135	Target Neighborhood Hits	1373	Shared Neighborhood Hits	40
SwissProt Accessions	Q6ZQ29, Q7TSS8	Gene names	Taok2, Kiaa0881
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2).

HERC2_MOUSE
θ value	1.81305 (rank : 65)	NC score	0.018868 (rank : 99)
Query Neighborhood Hits	135	Target Neighborhood Hits	167	Shared Neighborhood Hits	6
SwissProt Accessions	Q4U2R1, O88473, Q3TRJ8, Q3TS47, Q3TST2, Q3UFQ6, Q3URH7, Q5DU32, Q7TPR5, Q80VV7, Q9QYT1, Q9Z168, Q9Z171	Gene names	Herc2, jdf2, Kiaa0393, rjs
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

NACAM_MOUSE
θ value	1.81305 (rank : 66)	NC score	0.036174 (rank : 44)
Query Neighborhood Hits	135	Target Neighborhood Hits	1866	Shared Neighborhood Hits	47
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NIPBL_HUMAN
θ value	1.81305 (rank : 67)	NC score	0.043855 (rank : 32)
Query Neighborhood Hits	135	Target Neighborhood Hits	1311	Shared Neighborhood Hits	71
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

PHLPP_HUMAN
θ value	1.81305 (rank : 68)	NC score	0.011905 (rank : 122)
Query Neighborhood Hits	135	Target Neighborhood Hits	604	Shared Neighborhood Hits	10
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

SMBP2_MOUSE
θ value	1.81305 (rank : 69)	NC score	0.017543 (rank : 103)
Query Neighborhood Hits	135	Target Neighborhood Hits	104	Shared Neighborhood Hits	8
SwissProt Accessions	P40694	Gene names	Ighmbp2, Smbp-2, Smbp2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Cardiac transcription factor 1) (CATF1).

ARI4A_HUMAN
θ value	2.36792 (rank : 70)	NC score	0.043990 (rank : 31)
Query Neighborhood Hits	135	Target Neighborhood Hits	434	Shared Neighborhood Hits	44
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

CYTSA_HUMAN
θ value	2.36792 (rank : 71)	NC score	0.025782 (rank : 78)
Query Neighborhood Hits	135	Target Neighborhood Hits	1138	Shared Neighborhood Hits	50
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

DYRK4_HUMAN
θ value	2.36792 (rank : 72)	NC score	0.006519 (rank : 134)
Query Neighborhood Hits	135	Target Neighborhood Hits	750	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NR20, Q8NEF2, Q92631	Gene names	DYRK4
Domain Architecture	No domain graphic available
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 4 (EC 2.7.12.1).

K0431_HUMAN
θ value	2.36792 (rank : 73)	NC score	0.025665 (rank : 79)
Query Neighborhood Hits	135	Target Neighborhood Hits	211	Shared Neighborhood Hits	4
SwissProt Accessions	O43313	Gene names	KIAA0431
Domain Architecture	No domain graphic available
Description	Protein KIAA0431.

PARG_HUMAN
θ value	2.36792 (rank : 74)	NC score	0.034386 (rank : 49)
Query Neighborhood Hits	135	Target Neighborhood Hits	97	Shared Neighborhood Hits	11
SwissProt Accessions	Q86W56, Q6E4P6, Q6E4P7, Q7Z742, Q9Y4W7	Gene names	PARG
Domain Architecture	No domain graphic available
Description	Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143).

SYCP1_MOUSE
θ value	2.36792 (rank : 75)	NC score	0.029293 (rank : 67)
Query Neighborhood Hits	135	Target Neighborhood Hits	1456	Shared Neighborhood Hits	54
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

UGGG1_MOUSE
θ value	2.36792 (rank : 76)	NC score	0.026678 (rank : 75)
Query Neighborhood Hits	135	Target Neighborhood Hits	24	Shared Neighborhood Hits	6
SwissProt Accessions	Q6P5E4, Q6NV70	Gene names	Ugcgl1, Gt, Uggt, Ugt1, Ugtr
Domain Architecture	No domain graphic available
Description	UDP-glucose:glycoprotein glucosyltransferase 1 precursor (EC 2.4.1.-) (UDP-glucose ceramide glucosyltransferase-like 1) (UDP-- Glc:glycoprotein glucosyltransferase).

ZIM2_HUMAN
θ value	2.36792 (rank : 77)	NC score	0.000055 (rank : 140)
Query Neighborhood Hits	135	Target Neighborhood Hits	718	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZV7	Gene names	ZIM2
Domain Architecture
Description	Zinc finger imprinted 2.

K1H1_HUMAN
θ value	3.0926 (rank : 78)	NC score	0.015263 (rank : 116)
Query Neighborhood Hits	135	Target Neighborhood Hits	433	Shared Neighborhood Hits	26
SwissProt Accessions	Q15323	Gene names	KRTHA1, HHA1, HKA1
Domain Architecture
Description	Keratin, type I cuticular Ha1 (Hair keratin, type I Ha1).

PHLPP_MOUSE
θ value	3.0926 (rank : 79)	NC score	0.010073 (rank : 128)
Query Neighborhood Hits	135	Target Neighborhood Hits	394	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CHE4, Q6PCN0, Q8QZU8, Q8R5E5, Q99KL6	Gene names	Phlpp, Kiaa0606, Plekhe1, Scop
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein).

CEBPZ_HUMAN
θ value	4.03905 (rank : 80)	NC score	0.016373 (rank : 110)
Query Neighborhood Hits	135	Target Neighborhood Hits	87	Shared Neighborhood Hits	8
SwissProt Accessions	Q03701, Q8NE75	Gene names	CEBPZ, CBF2
Domain Architecture
Description	CCAAT/enhancer-binding protein zeta (CCAAT-box-binding transcription factor) (CCAAT-binding factor) (CBF).

KIF4A_HUMAN
θ value	4.03905 (rank : 81)	NC score	0.017868 (rank : 102)
Query Neighborhood Hits	135	Target Neighborhood Hits	1159	Shared Neighborhood Hits	45
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

NO40_HUMAN
θ value	4.03905 (rank : 82)	NC score	0.030007 (rank : 64)
Query Neighborhood Hits	135	Target Neighborhood Hits	47	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NP64, Q6PKH4, Q9NYG4, Q9P0M8	Gene names	ZCCHC17, PS1D
Domain Architecture	No domain graphic available
Description	Nucleolar protein of 40 kDa (pNO40) (Zinc finger CCHC domain- containing protein 17) (Putative S1 RNA-binding domain protein) (PS1D protein) (Pnn-interacting nucleolar protein).

NRX3A_HUMAN
θ value	4.03905 (rank : 83)	NC score	0.009331 (rank : 130)
Query Neighborhood Hits	135	Target Neighborhood Hits	164	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

NRX3B_HUMAN
θ value	4.03905 (rank : 84)	NC score	0.015586 (rank : 115)
Query Neighborhood Hits	135	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HDB5	Gene names	NRXN3, KIAA0743
Domain Architecture	No domain graphic available
Description	Neurexin-3-beta precursor (Neurexin III-beta).

PEG3_HUMAN
θ value	4.03905 (rank : 85)	NC score	0.000586 (rank : 139)
Query Neighborhood Hits	135	Target Neighborhood Hits	800	Shared Neighborhood Hits	10
SwissProt Accessions	Q9GZU2, P78418, Q5H9P9, Q7Z7H7, Q8TF75, Q9GZY2	Gene names	PEG3, KIAA0287
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein.

PEX5_HUMAN
θ value	4.03905 (rank : 86)	NC score	0.029654 (rank : 66)
Query Neighborhood Hits	135	Target Neighborhood Hits	92	Shared Neighborhood Hits	5
SwissProt Accessions	P50542, Q15115, Q15266	Gene names	PEX5, PXR1
Domain Architecture
Description	Peroxisomal targeting signal 1 receptor (Peroxisome receptor 1) (Peroxisomal C-terminal targeting signal import receptor) (PTS1-BP) (Peroxin-5) (PTS1 receptor).

RBBP6_HUMAN
θ value	4.03905 (rank : 87)	NC score	0.069619 (rank : 13)
Query Neighborhood Hits	135	Target Neighborhood Hits	1135	Shared Neighborhood Hits	56
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RL1D1_HUMAN
θ value	4.03905 (rank : 88)	NC score	0.040426 (rank : 37)
Query Neighborhood Hits	135	Target Neighborhood Hits	180	Shared Neighborhood Hits	33
SwissProt Accessions	O76021, Q6PL22, Q8IWS7, Q8WUZ1, Q9HDA9, Q9Y3Z9	Gene names	RSL1D1, CATX11, CSIG, PBK1
Domain Architecture	No domain graphic available
Description	Ribosomal L1 domain-containing protein 1 (Cellular senescence- inhibited gene protein) (Protein PBK1) (CATX-11).

SP110_HUMAN
θ value	4.03905 (rank : 89)	NC score	0.016086 (rank : 111)
Query Neighborhood Hits	135	Target Neighborhood Hits	141	Shared Neighborhood Hits	14
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

TDRD5_HUMAN
θ value	4.03905 (rank : 90)	NC score	0.019486 (rank : 95)
Query Neighborhood Hits	135	Target Neighborhood Hits	65	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NAT2, Q5VTV0	Gene names	TDRD5
Domain Architecture
Description	Tudor domain-containing protein 5.

APC_HUMAN
θ value	5.27518 (rank : 91)	NC score	0.029751 (rank : 65)
Query Neighborhood Hits	135	Target Neighborhood Hits	603	Shared Neighborhood Hits	43
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

BRD9_MOUSE
θ value	5.27518 (rank : 92)	NC score	0.010605 (rank : 127)
Query Neighborhood Hits	135	Target Neighborhood Hits	84	Shared Neighborhood Hits	7
SwissProt Accessions	Q3UQU0, Q5FWH1, Q811F7	Gene names	Brd9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9.

K0196_HUMAN
θ value	5.27518 (rank : 93)	NC score	0.018421 (rank : 100)
Query Neighborhood Hits	135	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q12768, Q3KQX5, Q8TBQ2	Gene names	KIAA0196
Domain Architecture	No domain graphic available
Description	Protein KIAA0196.

MCM3_HUMAN
θ value	5.27518 (rank : 94)	NC score	0.014556 (rank : 119)
Query Neighborhood Hits	135	Target Neighborhood Hits	87	Shared Neighborhood Hits	17
SwissProt Accessions	P25205, Q92660, Q9BTR3, Q9NUE7	Gene names	MCM3
Domain Architecture
Description	DNA replication licensing factor MCM3 (DNA polymerase alpha holoenzyme-associated protein P1) (RLF subunit beta) (P102 protein) (P1-MCM3).

MY18A_MOUSE
θ value	5.27518 (rank : 95)	NC score	0.025568 (rank : 81)
Query Neighborhood Hits	135	Target Neighborhood Hits	1989	Shared Neighborhood Hits	67
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

NO40_MOUSE
θ value	5.27518 (rank : 96)	NC score	0.027028 (rank : 73)
Query Neighborhood Hits	135	Target Neighborhood Hits	53	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ESX4	Gene names	Zcchc17, Ps1d
Domain Architecture	No domain graphic available
Description	Nucleolar protein of 40 kDa (pNO40) (Zinc finger CCHC domain- containing protein 17) (Putative S1 RNA-binding domain protein) (PS1D protein).

NUCKS_MOUSE
θ value	5.27518 (rank : 97)	NC score	0.052666 (rank : 22)
Query Neighborhood Hits	135	Target Neighborhood Hits	114	Shared Neighborhood Hits	22
SwissProt Accessions	Q80XU3, Q8BVD8	Gene names	Nucks1, Nucks
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (JC7).

SL9A3_HUMAN
θ value	5.27518 (rank : 98)	NC score	0.008992 (rank : 131)
Query Neighborhood Hits	135	Target Neighborhood Hits	63	Shared Neighborhood Hits	5
SwissProt Accessions	P48764	Gene names	SLC9A3, NHE3
Domain Architecture
Description	Sodium/hydrogen exchanger 3 (Na(+)/H(+) exchanger 3) (NHE-3) (Solute carrier family 9 member 3).

SYNE1_HUMAN
θ value	5.27518 (rank : 99)	NC score	0.022048 (rank : 87)
Query Neighborhood Hits	135	Target Neighborhood Hits	1484	Shared Neighborhood Hits	48
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

ATF6B_HUMAN
θ value	6.88961 (rank : 100)	NC score	0.010989 (rank : 125)
Query Neighborhood Hits	135	Target Neighborhood Hits	122	Shared Neighborhood Hits	5
SwissProt Accessions	Q99941, Q13269, Q14343, Q14345, Q99635, Q99637, Q9H3V9, Q9H3W1, Q9NPL0	Gene names	CREBL1, G13
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp) (Protein G13).

DMD_HUMAN
θ value	6.88961 (rank : 101)	NC score	0.020220 (rank : 92)
Query Neighborhood Hits	135	Target Neighborhood Hits	1135	Shared Neighborhood Hits	43
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

ELOA1_HUMAN
θ value	6.88961 (rank : 102)	NC score	0.023055 (rank : 85)
Query Neighborhood Hits	135	Target Neighborhood Hits	388	Shared Neighborhood Hits	29
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

GA2L3_HUMAN
θ value	6.88961 (rank : 103)	NC score	0.027266 (rank : 72)
Query Neighborhood Hits	135	Target Neighborhood Hits	189	Shared Neighborhood Hits	17
SwissProt Accessions	Q86XJ1	Gene names	GAS2L3
Domain Architecture	No domain graphic available
Description	GAS2-like protein 3 (Growth arrest-specific 2-like 3).

GHR_MOUSE
θ value	6.88961 (rank : 104)	NC score	0.011632 (rank : 124)
Query Neighborhood Hits	135	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	P16882, P16590, Q61653, Q6DI66, Q80W86, Q8R1M5, Q920Z3, Q9R264	Gene names	Ghr
Domain Architecture
Description	Growth hormone receptor precursor (GH receptor) (Somatotropin receptor) [Contains: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)].

K0196_MOUSE
θ value	6.88961 (rank : 105)	NC score	0.017268 (rank : 107)
Query Neighborhood Hits	135	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C2E7, Q8BGY1, Q8K2J2	Gene names	Kiaa0196
Domain Architecture	No domain graphic available
Description	Protein KIAA0196.

MCM3_MOUSE
θ value	6.88961 (rank : 106)	NC score	0.016689 (rank : 109)
Query Neighborhood Hits	135	Target Neighborhood Hits	95	Shared Neighborhood Hits	19
SwissProt Accessions	P25206, Q61492	Gene names	Mcm3, Mcmd, Mcmd3
Domain Architecture
Description	DNA replication licensing factor MCM3 (DNA polymerase alpha holoenzyme-associated protein P1) (P1-MCM3).

MILK1_MOUSE
θ value	6.88961 (rank : 107)	NC score	0.017297 (rank : 106)
Query Neighborhood Hits	135	Target Neighborhood Hits	788	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MYH3_HUMAN
θ value	6.88961 (rank : 108)	NC score	0.019805 (rank : 94)
Query Neighborhood Hits	135	Target Neighborhood Hits	1660	Shared Neighborhood Hits	56
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

NOP14_MOUSE
θ value	6.88961 (rank : 109)	NC score	0.032284 (rank : 54)
Query Neighborhood Hits	135	Target Neighborhood Hits	324	Shared Neighborhood Hits	30
SwissProt Accessions	Q8R3N1	Gene names	Nop14
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

PACN2_MOUSE
θ value	6.88961 (rank : 110)	NC score	0.015607 (rank : 114)
Query Neighborhood Hits	135	Target Neighborhood Hits	382	Shared Neighborhood Hits	20
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PRKX_HUMAN
θ value	6.88961 (rank : 111)	NC score	0.002470 (rank : 138)
Query Neighborhood Hits	135	Target Neighborhood Hits	847	Shared Neighborhood Hits	9
SwissProt Accessions	P51817	Gene names	PRKX, PKX1
Domain Architecture
Description	Serine/threonine-protein kinase PRKX (EC 2.7.11.1) (Protein kinase PKX1).

RGS3_HUMAN
θ value	6.88961 (rank : 112)	NC score	0.020838 (rank : 89)
Query Neighborhood Hits	135	Target Neighborhood Hits	1375	Shared Neighborhood Hits	30
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RYBP_MOUSE
θ value	6.88961 (rank : 113)	NC score	0.015659 (rank : 113)
Query Neighborhood Hits	135	Target Neighborhood Hits	39	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CCI5, Q9WVK2	Gene names	Rybp, Dedaf
Domain Architecture	No domain graphic available
Description	RING1 and YY1-binding protein (Death effector domain-associated factor) (DED-associated factor).

SPAST_HUMAN
θ value	6.88961 (rank : 114)	NC score	0.004693 (rank : 137)
Query Neighborhood Hits	135	Target Neighborhood Hits	100	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UBP0, Q9UPR9	Gene names	SPAST, KIAA1083, SPG4
Domain Architecture
Description	Spastin.

SSH1_HUMAN
θ value	6.88961 (rank : 115)	NC score	0.005949 (rank : 136)
Query Neighborhood Hits	135	Target Neighborhood Hits	164	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WYL5, Q6P6C0, Q8N9A7, Q8WYL3, Q8WYL4, Q9P2P8	Gene names	SSH1, KIAA1298, SSH1L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (hSSH-1L).

TULP1_MOUSE
θ value	6.88961 (rank : 116)	NC score	0.017531 (rank : 104)
Query Neighborhood Hits	135	Target Neighborhood Hits	146	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Z273	Gene names	Tulp1
Domain Architecture
Description	Tubby-related protein 1 (Tubby-like protein 1).

U2AFL_HUMAN
θ value	6.88961 (rank : 117)	NC score	0.021326 (rank : 88)
Query Neighborhood Hits	135	Target Neighborhood Hits	503	Shared Neighborhood Hits	35
SwissProt Accessions	Q15695, Q13570	Gene names	ZRSR1, U2AF1-RS1, U2AF1L1, U2AF1RS1, U2AFBPL
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 1 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1).

AFF4_HUMAN
θ value	8.99809 (rank : 118)	NC score	0.043622 (rank : 33)
Query Neighborhood Hits	135	Target Neighborhood Hits	611	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

AFF4_MOUSE
θ value	8.99809 (rank : 119)	NC score	0.035356 (rank : 47)
Query Neighborhood Hits	135	Target Neighborhood Hits	581	Shared Neighborhood Hits	46
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

ANK2_HUMAN
θ value	8.99809 (rank : 120)	NC score	0.019425 (rank : 96)
Query Neighborhood Hits	135	Target Neighborhood Hits	1615	Shared Neighborhood Hits	56
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ATRX_HUMAN
θ value	8.99809 (rank : 121)	NC score	0.039843 (rank : 38)
Query Neighborhood Hits	135	Target Neighborhood Hits	842	Shared Neighborhood Hits	61
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

BCCIP_HUMAN
θ value	8.99809 (rank : 122)	NC score	0.013342 (rank : 121)
Query Neighborhood Hits	135	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q9P287, Q8ND15, Q96GC4, Q9P288	Gene names	BCCIP, TOK1
Domain Architecture	No domain graphic available
Description	BRCA2 and CDKN1A-interacting protein (Protein TOK-1).

BPAEA_HUMAN
θ value	8.99809 (rank : 123)	NC score	0.019129 (rank : 97)
Query Neighborhood Hits	135	Target Neighborhood Hits	1369	Shared Neighborhood Hits	47
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CS021_MOUSE
θ value	8.99809 (rank : 124)	NC score	0.010791 (rank : 126)
Query Neighborhood Hits	135	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D279, Q3UI04	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf21 homolog.

DCX_HUMAN
θ value	8.99809 (rank : 125)	NC score	0.006237 (rank : 135)
Query Neighborhood Hits	135	Target Neighborhood Hits	141	Shared Neighborhood Hits	5
SwissProt Accessions	O43602, O43911	Gene names	DCX, DBCN, LISX
Domain Architecture
Description	Neuronal migration protein doublecortin (Lissencephalin-X) (Lis-X) (Doublin).

GEMI_HUMAN
θ value	8.99809 (rank : 126)	NC score	0.017480 (rank : 105)
Query Neighborhood Hits	135	Target Neighborhood Hits	192	Shared Neighborhood Hits	13
SwissProt Accessions	O75496, Q9H1Z1	Gene names	GMNN
Domain Architecture
Description	Geminin.

HMMR_MOUSE
θ value	8.99809 (rank : 127)	NC score	0.025554 (rank : 82)
Query Neighborhood Hits	135	Target Neighborhood Hits	1178	Shared Neighborhood Hits	46
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

ITSN1_HUMAN
θ value	8.99809 (rank : 128)	NC score	0.018944 (rank : 98)
Query Neighborhood Hits	135	Target Neighborhood Hits	1757	Shared Neighborhood Hits	59
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

K0423_MOUSE
θ value	8.99809 (rank : 129)	NC score	0.019968 (rank : 93)
Query Neighborhood Hits	135	Target Neighborhood Hits	115	Shared Neighborhood Hits	6
SwissProt Accessions	Q6A070	Gene names	Kiaa0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

MBB1A_HUMAN
θ value	8.99809 (rank : 130)	NC score	0.050955 (rank : 23)
Query Neighborhood Hits	135	Target Neighborhood Hits	665	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

NIN_MOUSE
θ value	8.99809 (rank : 131)	NC score	0.026531 (rank : 76)
Query Neighborhood Hits	135	Target Neighborhood Hits	1376	Shared Neighborhood Hits	48
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

OSBL8_HUMAN
θ value	8.99809 (rank : 132)	NC score	0.007455 (rank : 132)
Query Neighborhood Hits	135	Target Neighborhood Hits	289	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

PHLB2_HUMAN
θ value	8.99809 (rank : 133)	NC score	0.026453 (rank : 77)
Query Neighborhood Hits	135	Target Neighborhood Hits	964	Shared Neighborhood Hits	42
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

RAG2_MOUSE
θ value	8.99809 (rank : 134)	NC score	0.009672 (rank : 129)
Query Neighborhood Hits	135	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	P21784	Gene names	Rag2, Rag-2
Domain Architecture
Description	V(D)J recombination-activating protein 2 (RAG-2).

SYAP1_MOUSE
θ value	8.99809 (rank : 135)	NC score	0.023710 (rank : 83)
Query Neighborhood Hits	135	Target Neighborhood Hits	55	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D5V6, Q3UI67, Q9D870	Gene names	Syap1
Domain Architecture
Description	Synapse-associated protein 1.

ADDB_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.055673 (rank : 19)
Query Neighborhood Hits	135	Target Neighborhood Hits	574	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

AKA12_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.061595 (rank : 17)
Query Neighborhood Hits	135	Target Neighborhood Hits	825	Shared Neighborhood Hits	49
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

DSPP_MOUSE
θ value	θ > 10 (rank : 138)	NC score	0.050902 (rank : 24)
Query Neighborhood Hits	135	Target Neighborhood Hits	491	Shared Neighborhood Hits	33
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

NOLC1_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.072171 (rank : 12)
Query Neighborhood Hits	135	Target Neighborhood Hits	452	Shared Neighborhood Hits	43
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

TRDN_HUMAN
θ value	θ > 10 (rank : 140)	NC score	0.052989 (rank : 21)
Query Neighborhood Hits	135	Target Neighborhood Hits	542	Shared Neighborhood Hits	59
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

Hits sorted by NC score

TOP2A_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	135	Target Neighborhood Hits	135	Shared Neighborhood Hits	135
SwissProt Accessions	P11388, Q71UN1, Q9HB24, Q9HB25, Q9HB26, Q9UP44, Q9UQP9	Gene names	TOP2A, TOP2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

TOP2A_MOUSE
NC score	0.972769 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	135	Target Neighborhood Hits	101	Shared Neighborhood Hits	29
SwissProt Accessions	Q01320	Gene names	Top2a, Top-2, Top2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

TOP2B_MOUSE
NC score	0.972292 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	135	Target Neighborhood Hits	80	Shared Neighborhood Hits	21
SwissProt Accessions	Q64511, Q7TQG4	Gene names	Top2b
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).

TOP2B_HUMAN
NC score	0.970087 (rank : 4)	θ value	0 (rank : 3)
Query Neighborhood Hits	135	Target Neighborhood Hits	101	Shared Neighborhood Hits	16
SwissProt Accessions	Q02880, Q13600, Q9UMG8, Q9UQP8	Gene names	TOP2B
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).

IWS1_HUMAN
NC score	0.105387 (rank : 5)	θ value	0.0148317 (rank : 8)
Query Neighborhood Hits	135	Target Neighborhood Hits	1241	Shared Neighborhood Hits	63
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

IWS1_MOUSE
NC score	0.092623 (rank : 6)	θ value	0.0431538 (rank : 10)
Query Neighborhood Hits	135	Target Neighborhood Hits	1258	Shared Neighborhood Hits	57
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

TXND2_MOUSE
NC score	0.091189 (rank : 7)	θ value	0.000602161 (rank : 5)
Query Neighborhood Hits	135	Target Neighborhood Hits	828	Shared Neighborhood Hits	57
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

R51A1_MOUSE
NC score	0.081582 (rank : 8)	θ value	0.279714 (rank : 22)
Query Neighborhood Hits	135	Target Neighborhood Hits	164	Shared Neighborhood Hits	24
SwissProt Accessions	Q8C551, O55219, Q8BP36, Q99L94, Q9D0J0	Gene names	Rad51ap1
Domain Architecture	No domain graphic available
Description	RAD51-associated protein 1 (RAD51-interacting protein) (RAB22).

TXND2_HUMAN
NC score	0.077542 (rank : 9)	θ value	0.279714 (rank : 23)
Query Neighborhood Hits	135	Target Neighborhood Hits	793	Shared Neighborhood Hits	42
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

RFC1_HUMAN
NC score	0.076740 (rank : 10)	θ value	1.06291 (rank : 54)
Query Neighborhood Hits	135	Target Neighborhood Hits	352	Shared Neighborhood Hits	34
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

TGON2_HUMAN
NC score	0.072634 (rank : 11)	θ value	0.00869519 (rank : 6)
Query Neighborhood Hits	135	Target Neighborhood Hits	1037	Shared Neighborhood Hits	48
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

NOLC1_HUMAN
NC score	0.072171 (rank : 12)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	135	Target Neighborhood Hits	452	Shared Neighborhood Hits	43
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

RBBP6_HUMAN
NC score	0.069619 (rank : 13)	θ value	4.03905 (rank : 87)
Query Neighborhood Hits	135	Target Neighborhood Hits	1135	Shared Neighborhood Hits	56
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RFC1_MOUSE
NC score	0.067443 (rank : 14)	θ value	0.0148317 (rank : 9)
Query Neighborhood Hits	135	Target Neighborhood Hits	290	Shared Neighborhood Hits	27
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

RSF1_HUMAN
NC score	0.063319 (rank : 15)	θ value	1.06291 (rank : 55)
Query Neighborhood Hits	135	Target Neighborhood Hits	539	Shared Neighborhood Hits	53
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

RRBP1_HUMAN
NC score	0.062064 (rank : 16)	θ value	0.47712 (rank : 35)
Query Neighborhood Hits	135	Target Neighborhood Hits	1306	Shared Neighborhood Hits	63
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

AKA12_HUMAN
NC score	0.061595 (rank : 17)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	135	Target Neighborhood Hits	825	Shared Neighborhood Hits	49
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

KI67_HUMAN
NC score	0.058456 (rank : 18)	θ value	0.813845 (rank : 45)
Query Neighborhood Hits	135	Target Neighborhood Hits	581	Shared Neighborhood Hits	41
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

ADDB_MOUSE
NC score	0.055673 (rank : 19)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	135	Target Neighborhood Hits	574	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

ATRX_MOUSE
NC score	0.055050 (rank : 20)	θ value	1.06291 (rank : 50)
Query Neighborhood Hits	135	Target Neighborhood Hits	682	Shared Neighborhood Hits	59
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

TRDN_HUMAN
NC score	0.052989 (rank : 21)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	135	Target Neighborhood Hits	542	Shared Neighborhood Hits	59
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

NUCKS_MOUSE
NC score	0.052666 (rank : 22)	θ value	5.27518 (rank : 97)
Query Neighborhood Hits	135	Target Neighborhood Hits	114	Shared Neighborhood Hits	22
SwissProt Accessions	Q80XU3, Q8BVD8	Gene names	Nucks1, Nucks
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (JC7).

MBB1A_HUMAN
NC score	0.050955 (rank : 23)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	135	Target Neighborhood Hits	665	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

DSPP_MOUSE
NC score	0.050902 (rank : 24)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	135	Target Neighborhood Hits	491	Shared Neighborhood Hits	33
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

LAD1_MOUSE
NC score	0.050478 (rank : 25)	θ value	0.163984 (rank : 18)
Query Neighborhood Hits	135	Target Neighborhood Hits	391	Shared Neighborhood Hits	30
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

MINT_MOUSE
NC score	0.049394 (rank : 26)	θ value	0.0113563 (rank : 7)
Query Neighborhood Hits	135	Target Neighborhood Hits	1514	Shared Neighborhood Hits	55
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

AHTF1_HUMAN
NC score	0.048152 (rank : 27)	θ value	0.365318 (rank : 24)
Query Neighborhood Hits	135	Target Neighborhood Hits	286	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WYP5, Q7Z4E3, Q8IZA4, Q96EH9, Q9Y4Q6	Gene names	AHCTF1, ELYS, TMBS62
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

K0146_HUMAN
NC score	0.047750 (rank : 28)	θ value	0.0736092 (rank : 12)
Query Neighborhood Hits	135	Target Neighborhood Hits	48	Shared Neighborhood Hits	5
SwissProt Accessions	Q14159, Q96BI5	Gene names	KIAA0146
Domain Architecture	No domain graphic available
Description	Protein KIAA0146.

SRRM2_MOUSE
NC score	0.045552 (rank : 29)	θ value	0.62314 (rank : 42)
Query Neighborhood Hits	135	Target Neighborhood Hits	1470	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

PCLO_HUMAN
NC score	0.044224 (rank : 30)	θ value	1.38821 (rank : 60)
Query Neighborhood Hits	135	Target Neighborhood Hits	2046	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

ARI4A_HUMAN
NC score	0.043990 (rank : 31)	θ value	2.36792 (rank : 70)
Query Neighborhood Hits	135	Target Neighborhood Hits	434	Shared Neighborhood Hits	44
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

NIPBL_HUMAN
NC score	0.043855 (rank : 32)	θ value	1.81305 (rank : 67)
Query Neighborhood Hits	135	Target Neighborhood Hits	1311	Shared Neighborhood Hits	71
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

AFF4_HUMAN
NC score	0.043622 (rank : 33)	θ value	8.99809 (rank : 118)
Query Neighborhood Hits	135	Target Neighborhood Hits	611	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

LSP1_MOUSE
NC score	0.043195 (rank : 34)	θ value	0.279714 (rank : 21)
Query Neighborhood Hits	135	Target Neighborhood Hits	125	Shared Neighborhood Hits	5
SwissProt Accessions	P19973, P97339, Q04950, Q62022, Q62023, Q62024, Q8CD28, Q99L65	Gene names	Lsp1, Pp52, S37, Wp34
Domain Architecture
Description	Lymphocyte-specific protein 1 (Protein pp52) (52 kDa phosphoprotein) (Lymphocyte-specific antigen WP34) (S37 protein).

BCAS1_HUMAN
NC score	0.042996 (rank : 35)	θ value	0.279714 (rank : 20)
Query Neighborhood Hits	135	Target Neighborhood Hits	133	Shared Neighborhood Hits	10
SwissProt Accessions	O75363, Q68CZ3	Gene names	BCAS1, AIBC1, NABC1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 1 (Novel amplified in breast cancer 1) (Amplified and overexpressed in breast cancer).

RN168_MOUSE
NC score	0.042291 (rank : 36)	θ value	0.0736092 (rank : 13)
Query Neighborhood Hits	135	Target Neighborhood Hits	440	Shared Neighborhood Hits	26
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RL1D1_HUMAN
NC score	0.040426 (rank : 37)	θ value	4.03905 (rank : 88)
Query Neighborhood Hits	135	Target Neighborhood Hits	180	Shared Neighborhood Hits	33
SwissProt Accessions	O76021, Q6PL22, Q8IWS7, Q8WUZ1, Q9HDA9, Q9Y3Z9	Gene names	RSL1D1, CATX11, CSIG, PBK1
Domain Architecture	No domain graphic available
Description	Ribosomal L1 domain-containing protein 1 (Cellular senescence- inhibited gene protein) (Protein PBK1) (CATX-11).

ATRX_HUMAN
NC score	0.039843 (rank : 38)	θ value	8.99809 (rank : 121)
Query Neighborhood Hits	135	Target Neighborhood Hits	842	Shared Neighborhood Hits	61
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

NKTR_HUMAN
NC score	0.039343 (rank : 39)	θ value	0.365318 (rank : 26)
Query Neighborhood Hits	135	Target Neighborhood Hits	658	Shared Neighborhood Hits	32
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

CASC5_HUMAN
NC score	0.037692 (rank : 40)	θ value	1.06291 (rank : 51)
Query Neighborhood Hits	135	Target Neighborhood Hits	376	Shared Neighborhood Hits	28
SwissProt Accessions	Q8NG31, Q8NHE1, Q8WXA6, Q9HCK2, Q9NR92	Gene names	CASC5, KIAA1570
Domain Architecture	No domain graphic available
Description	Protein CASC5 (Cancer susceptibility candidate gene 5 protein) (ALL1- fused gene from chromosome 15q14) (AF15q14) (D40/AF15q14 protein).

PRC1_HUMAN
NC score	0.037262 (rank : 41)	θ value	0.47712 (rank : 34)
Query Neighborhood Hits	135	Target Neighborhood Hits	328	Shared Neighborhood Hits	24
SwissProt Accessions	O43663, Q9BSB6	Gene names	PRC1
Domain Architecture	No domain graphic available
Description	Protein regulator of cytokinesis 1.

FA47A_HUMAN
NC score	0.036929 (rank : 42)	θ value	0.62314 (rank : 38)
Query Neighborhood Hits	135	Target Neighborhood Hits	451	Shared Neighborhood Hits	17
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

PIBF1_HUMAN
NC score	0.036225 (rank : 43)	θ value	0.813845 (rank : 49)
Query Neighborhood Hits	135	Target Neighborhood Hits	1041	Shared Neighborhood Hits	47
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

NACAM_MOUSE
NC score	0.036174 (rank : 44)	θ value	1.81305 (rank : 66)
Query Neighborhood Hits	135	Target Neighborhood Hits	1866	Shared Neighborhood Hits	47
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

TTF2_MOUSE
NC score	0.035442 (rank : 45)	θ value	0.0431538 (rank : 11)
Query Neighborhood Hits	135	Target Neighborhood Hits	364	Shared Neighborhood Hits	24
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

HOME1_MOUSE
NC score	0.035410 (rank : 46)	θ value	0.125558 (rank : 15)
Query Neighborhood Hits	135	Target Neighborhood Hits	630	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Z2Y3, Q8K3E1, Q8K4M8, Q9Z0E9, Q9Z216	Gene names	Homer1, Vesl1
Domain Architecture
Description	Homer protein homolog 1 (VASP/Ena-related gene up-regulated during seizure and LTP) (Vesl-1).

AFF4_MOUSE
NC score	0.035356 (rank : 47)	θ value	8.99809 (rank : 119)
Query Neighborhood Hits	135	Target Neighborhood Hits	581	Shared Neighborhood Hits	46
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

MDC1_HUMAN
NC score	0.035046 (rank : 48)	θ value	0.47712 (rank : 32)
Query Neighborhood Hits	135	Target Neighborhood Hits	1446	Shared Neighborhood Hits	45
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

PARG_HUMAN
NC score	0.034386 (rank : 49)	θ value	2.36792 (rank : 74)
Query Neighborhood Hits	135	Target Neighborhood Hits	97	Shared Neighborhood Hits	11
SwissProt Accessions	Q86W56, Q6E4P6, Q6E4P7, Q7Z742, Q9Y4W7	Gene names	PARG
Domain Architecture	No domain graphic available
Description	Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143).

SNPC2_HUMAN
NC score	0.034044 (rank : 50)	θ value	1.38821 (rank : 61)
Query Neighborhood Hits	135	Target Neighborhood Hits	56	Shared Neighborhood Hits	9
SwissProt Accessions	Q13487, Q13486	Gene names	SNAPC2, SNAP45
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 2 (SNAPc subunit 2) (snRNA- activating protein complex 45 kDa subunit) (SNAPc 45 kDa subunit) (Small nuclear RNA-activating complex polypeptide 2) (Proximal sequence element-binding transcription factor subunit delta) (PSE- binding factor subunit delta) (PTF subunit delta).

KMHN1_MOUSE
NC score	0.033737 (rank : 51)	θ value	0.163984 (rank : 17)
Query Neighborhood Hits	135	Target Neighborhood Hits	949	Shared Neighborhood Hits	39
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

GOGA5_MOUSE
NC score	0.033304 (rank : 52)	θ value	0.163984 (rank : 16)
Query Neighborhood Hits	135	Target Neighborhood Hits	1434	Shared Neighborhood Hits	52
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

MO4L1_MOUSE
NC score	0.032758 (rank : 53)	θ value	0.62314 (rank : 41)
Query Neighborhood Hits	135	Target Neighborhood Hits	51	Shared Neighborhood Hits	7
SwissProt Accessions	P60762, Q8BNY9, Q99MQ0	Gene names	Morf4l1, Mrg15, Tex189
Domain Architecture
Description	Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (Transcription factor-like protein MRG15) (Testis-expressed gene 189 protein).

NOP14_MOUSE
NC score	0.032284 (rank : 54)	θ value	6.88961 (rank : 109)
Query Neighborhood Hits	135	Target Neighborhood Hits	324	Shared Neighborhood Hits	30
SwissProt Accessions	Q8R3N1	Gene names	Nop14
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

MO4L1_HUMAN
NC score	0.031917 (rank : 55)	θ value	0.813845 (rank : 46)
Query Neighborhood Hits	135	Target Neighborhood Hits	51	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UBU8, O95899, Q5QTS1, Q6NVX8, Q86YT7, Q9HBP6, Q9NSW5	Gene names	MORF4L1, MRG15
Domain Architecture
Description	Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (Transcription factor-like protein MRG15) (MSL3-1 protein).

GOGB1_HUMAN
NC score	0.031626 (rank : 56)	θ value	0.47712 (rank : 30)
Query Neighborhood Hits	135	Target Neighborhood Hits	2297	Shared Neighborhood Hits	67
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

GOGA5_HUMAN
NC score	0.031555 (rank : 57)	θ value	0.813845 (rank : 44)
Query Neighborhood Hits	135	Target Neighborhood Hits	1168	Shared Neighborhood Hits	45
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

CUTL1_HUMAN
NC score	0.031253 (rank : 58)	θ value	0.47712 (rank : 29)
Query Neighborhood Hits	135	Target Neighborhood Hits	1574	Shared Neighborhood Hits	62
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

CASP_HUMAN
NC score	0.031179 (rank : 59)	θ value	0.47712 (rank : 28)
Query Neighborhood Hits	135	Target Neighborhood Hits	1131	Shared Neighborhood Hits	47
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CP135_HUMAN
NC score	0.031151 (rank : 60)	θ value	1.06291 (rank : 52)
Query Neighborhood Hits	135	Target Neighborhood Hits	1290	Shared Neighborhood Hits	46
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

PHLB2_MOUSE
NC score	0.031011 (rank : 61)	θ value	0.813845 (rank : 48)
Query Neighborhood Hits	135	Target Neighborhood Hits	1016	Shared Neighborhood Hits	47
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

CENPF_HUMAN
NC score	0.030872 (rank : 62)	θ value	0.365318 (rank : 25)
Query Neighborhood Hits	135	Target Neighborhood Hits	1932	Shared Neighborhood Hits	55
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

REST_MOUSE
NC score	0.030514 (rank : 63)	θ value	0.365318 (rank : 27)
Query Neighborhood Hits	135	Target Neighborhood Hits	1506	Shared Neighborhood Hits	56
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

NO40_HUMAN
NC score	0.030007 (rank : 64)	θ value	4.03905 (rank : 82)
Query Neighborhood Hits	135	Target Neighborhood Hits	47	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NP64, Q6PKH4, Q9NYG4, Q9P0M8	Gene names	ZCCHC17, PS1D
Domain Architecture	No domain graphic available
Description	Nucleolar protein of 40 kDa (pNO40) (Zinc finger CCHC domain- containing protein 17) (Putative S1 RNA-binding domain protein) (PS1D protein) (Pnn-interacting nucleolar protein).

APC_HUMAN
NC score	0.029751 (rank : 65)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	135	Target Neighborhood Hits	603	Shared Neighborhood Hits	43
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

PEX5_HUMAN
NC score	0.029654 (rank : 66)	θ value	4.03905 (rank : 86)
Query Neighborhood Hits	135	Target Neighborhood Hits	92	Shared Neighborhood Hits	5
SwissProt Accessions	P50542, Q15115, Q15266	Gene names	PEX5, PXR1
Domain Architecture
Description	Peroxisomal targeting signal 1 receptor (Peroxisome receptor 1) (Peroxisomal C-terminal targeting signal import receptor) (PTS1-BP) (Peroxin-5) (PTS1 receptor).

SYCP1_MOUSE
NC score	0.029293 (rank : 67)	θ value	2.36792 (rank : 75)
Query Neighborhood Hits	135	Target Neighborhood Hits	1456	Shared Neighborhood Hits	54
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

K0423_HUMAN
NC score	0.028689 (rank : 68)	θ value	1.38821 (rank : 58)
Query Neighborhood Hits	135	Target Neighborhood Hits	171	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y4F4, Q68D66, Q6PG27	Gene names	KIAA0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

LHR2A_HUMAN
NC score	0.028585 (rank : 69)	θ value	0.62314 (rank : 40)
Query Neighborhood Hits	135	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	O00534, Q6UN19, Q6UN20, Q9BVF8	Gene names	LOH11CR2A, BCSC1
Domain Architecture
Description	Loss of heterozygosity 11 chromosomal region 2 gene A protein (Breast cancer suppressor candidate 1) (BCSC-1).

UGGG1_HUMAN
NC score	0.028434 (rank : 70)	θ value	1.06291 (rank : 56)
Query Neighborhood Hits	135	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NYU2, Q8IW30, Q9H8I4	Gene names	UGCGL1, GT, UGGT, UGT1, UGTR
Domain Architecture	No domain graphic available
Description	UDP-glucose:glycoprotein glucosyltransferase 1 precursor (EC 2.4.1.-) (UDP-glucose ceramide glucosyltransferase-like 1) (UDP-- Glc:glycoprotein glucosyltransferase) (HUGT1).

TACC2_MOUSE
NC score	0.028080 (rank : 71)	θ value	1.38821 (rank : 63)
Query Neighborhood Hits	135	Target Neighborhood Hits	774	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

GA2L3_HUMAN
NC score	0.027266 (rank : 72)	θ value	6.88961 (rank : 103)
Query Neighborhood Hits	135	Target Neighborhood Hits	189	Shared Neighborhood Hits	17
SwissProt Accessions	Q86XJ1	Gene names	GAS2L3
Domain Architecture	No domain graphic available
Description	GAS2-like protein 3 (Growth arrest-specific 2-like 3).

NO40_MOUSE
NC score	0.027028 (rank : 73)	θ value	5.27518 (rank : 96)
Query Neighborhood Hits	135	Target Neighborhood Hits	53	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ESX4	Gene names	Zcchc17, Ps1d
Domain Architecture	No domain graphic available
Description	Nucleolar protein of 40 kDa (pNO40) (Zinc finger CCHC domain- containing protein 17) (Putative S1 RNA-binding domain protein) (PS1D protein).

TCAL5_HUMAN
NC score	0.026946 (rank : 74)	θ value	0.47712 (rank : 36)
Query Neighborhood Hits	135	Target Neighborhood Hits	806	Shared Neighborhood Hits	35
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

UGGG1_MOUSE
NC score	0.026678 (rank : 75)	θ value	2.36792 (rank : 76)
Query Neighborhood Hits	135	Target Neighborhood Hits	24	Shared Neighborhood Hits	6
SwissProt Accessions	Q6P5E4, Q6NV70	Gene names	Ugcgl1, Gt, Uggt, Ugt1, Ugtr
Domain Architecture	No domain graphic available
Description	UDP-glucose:glycoprotein glucosyltransferase 1 precursor (EC 2.4.1.-) (UDP-glucose ceramide glucosyltransferase-like 1) (UDP-- Glc:glycoprotein glucosyltransferase).

NIN_MOUSE
NC score	0.026531 (rank : 76)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	135	Target Neighborhood Hits	1376	Shared Neighborhood Hits	48
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

PHLB2_HUMAN
NC score	0.026453 (rank : 77)	θ value	8.99809 (rank : 133)
Query Neighborhood Hits	135	Target Neighborhood Hits	964	Shared Neighborhood Hits	42
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

CYTSA_HUMAN
NC score	0.025782 (rank : 78)	θ value	2.36792 (rank : 71)
Query Neighborhood Hits	135	Target Neighborhood Hits	1138	Shared Neighborhood Hits	50
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

K0431_HUMAN
NC score	0.025665 (rank : 79)	θ value	2.36792 (rank : 73)
Query Neighborhood Hits	135	Target Neighborhood Hits	211	Shared Neighborhood Hits	4
SwissProt Accessions	O43313	Gene names	KIAA0431
Domain Architecture	No domain graphic available
Description	Protein KIAA0431.

MY18A_HUMAN
NC score	0.025624 (rank : 80)	θ value	0.813845 (rank : 47)
Query Neighborhood Hits	135	Target Neighborhood Hits	1929	Shared Neighborhood Hits	60
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MY18A_MOUSE
NC score	0.025568 (rank : 81)	θ value	5.27518 (rank : 95)
Query Neighborhood Hits	135	Target Neighborhood Hits	1989	Shared Neighborhood Hits	67
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

HMMR_MOUSE
NC score	0.025554 (rank : 82)	θ value	8.99809 (rank : 127)
Query Neighborhood Hits	135	Target Neighborhood Hits	1178	Shared Neighborhood Hits	46
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

SYAP1_MOUSE
NC score	0.023710 (rank : 83)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	135	Target Neighborhood Hits	55	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D5V6, Q3UI67, Q9D870	Gene names	Syap1
Domain Architecture
Description	Synapse-associated protein 1.

DIDO1_HUMAN
NC score	0.023389 (rank : 84)	θ value	1.38821 (rank : 57)
Query Neighborhood Hits	135	Target Neighborhood Hits	960	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

ELOA1_HUMAN
NC score	0.023055 (rank : 85)	θ value	6.88961 (rank : 102)
Query Neighborhood Hits	135	Target Neighborhood Hits	388	Shared Neighborhood Hits	29
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

MYO5C_HUMAN
NC score	0.022420 (rank : 86)	θ value	0.47712 (rank : 33)
Query Neighborhood Hits	135	Target Neighborhood Hits	1206	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

SYNE1_HUMAN
NC score	0.022048 (rank : 87)	θ value	5.27518 (rank : 99)
Query Neighborhood Hits	135	Target Neighborhood Hits	1484	Shared Neighborhood Hits	48
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

U2AFL_HUMAN
NC score	0.021326 (rank : 88)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	135	Target Neighborhood Hits	503	Shared Neighborhood Hits	35
SwissProt Accessions	Q15695, Q13570	Gene names	ZRSR1, U2AF1-RS1, U2AF1L1, U2AF1RS1, U2AFBPL
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 1 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1).

RGS3_HUMAN
NC score	0.020838 (rank : 89)	θ value	6.88961 (rank : 112)
Query Neighborhood Hits	135	Target Neighborhood Hits	1375	Shared Neighborhood Hits	30
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

DDX21_MOUSE
NC score	0.020834 (rank : 90)	θ value	0.62314 (rank : 37)
Query Neighborhood Hits	135	Target Neighborhood Hits	350	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

HERC2_HUMAN
NC score	0.020384 (rank : 91)	θ value	0.62314 (rank : 39)
Query Neighborhood Hits	135	Target Neighborhood Hits	163	Shared Neighborhood Hits	6
SwissProt Accessions	O95714, Q86SV7, Q86SV8, Q86SV9, Q86YY3, Q86YY4, Q86YY5, Q86YY6, Q86YY7, Q86YY8, Q86YY9, Q86YZ0, Q86YZ1	Gene names	HERC2
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

DMD_HUMAN
NC score	0.020220 (rank : 92)	θ value	6.88961 (rank : 101)
Query Neighborhood Hits	135	Target Neighborhood Hits	1135	Shared Neighborhood Hits	43
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

K0423_MOUSE
NC score	0.019968 (rank : 93)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	135	Target Neighborhood Hits	115	Shared Neighborhood Hits	6
SwissProt Accessions	Q6A070	Gene names	Kiaa0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

MYH3_HUMAN
NC score	0.019805 (rank : 94)	θ value	6.88961 (rank : 108)
Query Neighborhood Hits	135	Target Neighborhood Hits	1660	Shared Neighborhood Hits	56
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

TDRD5_HUMAN
NC score	0.019486 (rank : 95)	θ value	4.03905 (rank : 90)
Query Neighborhood Hits	135	Target Neighborhood Hits	65	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NAT2, Q5VTV0	Gene names	TDRD5
Domain Architecture
Description	Tudor domain-containing protein 5.

ANK2_HUMAN
NC score	0.019425 (rank : 96)	θ value	8.99809 (rank : 120)
Query Neighborhood Hits	135	Target Neighborhood Hits	1615	Shared Neighborhood Hits	56
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

BPAEA_HUMAN
NC score	0.019129 (rank : 97)	θ value	8.99809 (rank : 123)
Query Neighborhood Hits	135	Target Neighborhood Hits	1369	Shared Neighborhood Hits	47
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

ITSN1_HUMAN
NC score	0.018944 (rank : 98)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	135	Target Neighborhood Hits	1757	Shared Neighborhood Hits	59
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

HERC2_MOUSE
NC score	0.018868 (rank : 99)	θ value	1.81305 (rank : 65)
Query Neighborhood Hits	135	Target Neighborhood Hits	167	Shared Neighborhood Hits	6
SwissProt Accessions	Q4U2R1, O88473, Q3TRJ8, Q3TS47, Q3TST2, Q3UFQ6, Q3URH7, Q5DU32, Q7TPR5, Q80VV7, Q9QYT1, Q9Z168, Q9Z171	Gene names	Herc2, jdf2, Kiaa0393, rjs
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

K0196_HUMAN
NC score	0.018421 (rank : 100)	θ value	5.27518 (rank : 93)
Query Neighborhood Hits	135	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q12768, Q3KQX5, Q8TBQ2	Gene names	KIAA0196
Domain Architecture	No domain graphic available
Description	Protein KIAA0196.

MARE1_HUMAN
NC score	0.018340 (rank : 101)	θ value	1.38821 (rank : 59)
Query Neighborhood Hits	135	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q15691	Gene names	MAPRE1
Domain Architecture
Description	Microtubule-associated protein RP/EB family member 1 (APC-binding protein EB1) (End-binding protein 1) (EB1).

KIF4A_HUMAN
NC score	0.017868 (rank : 102)	θ value	4.03905 (rank : 81)
Query Neighborhood Hits	135	Target Neighborhood Hits	1159	Shared Neighborhood Hits	45
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

SMBP2_MOUSE
NC score	0.017543 (rank : 103)	θ value	1.81305 (rank : 69)
Query Neighborhood Hits	135	Target Neighborhood Hits	104	Shared Neighborhood Hits	8
SwissProt Accessions	P40694	Gene names	Ighmbp2, Smbp-2, Smbp2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Cardiac transcription factor 1) (CATF1).

TULP1_MOUSE
NC score	0.017531 (rank : 104)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	135	Target Neighborhood Hits	146	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Z273	Gene names	Tulp1
Domain Architecture
Description	Tubby-related protein 1 (Tubby-like protein 1).

GEMI_HUMAN
NC score	0.017480 (rank : 105)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	135	Target Neighborhood Hits	192	Shared Neighborhood Hits	13
SwissProt Accessions	O75496, Q9H1Z1	Gene names	GMNN
Domain Architecture
Description	Geminin.

MILK1_MOUSE
NC score	0.017297 (rank : 106)	θ value	6.88961 (rank : 107)
Query Neighborhood Hits	135	Target Neighborhood Hits	788	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

K0196_MOUSE
NC score	0.017268 (rank : 107)	θ value	6.88961 (rank : 105)
Query Neighborhood Hits	135	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C2E7, Q8BGY1, Q8K2J2	Gene names	Kiaa0196
Domain Architecture	No domain graphic available
Description	Protein KIAA0196.

TAOK2_MOUSE
NC score	0.017221 (rank : 108)	θ value	1.38821 (rank : 64)
Query Neighborhood Hits	135	Target Neighborhood Hits	1373	Shared Neighborhood Hits	40
SwissProt Accessions	Q6ZQ29, Q7TSS8	Gene names	Taok2, Kiaa0881
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2).

MCM3_MOUSE
NC score	0.016689 (rank : 109)	θ value	6.88961 (rank : 106)
Query Neighborhood Hits	135	Target Neighborhood Hits	95	Shared Neighborhood Hits	19
SwissProt Accessions	P25206, Q61492	Gene names	Mcm3, Mcmd, Mcmd3
Domain Architecture
Description	DNA replication licensing factor MCM3 (DNA polymerase alpha holoenzyme-associated protein P1) (P1-MCM3).

CEBPZ_HUMAN
NC score	0.016373 (rank : 110)	θ value	4.03905 (rank : 80)
Query Neighborhood Hits	135	Target Neighborhood Hits	87	Shared Neighborhood Hits	8
SwissProt Accessions	Q03701, Q8NE75	Gene names	CEBPZ, CBF2
Domain Architecture
Description	CCAAT/enhancer-binding protein zeta (CCAAT-box-binding transcription factor) (CCAAT-binding factor) (CBF).

SP110_HUMAN
NC score	0.016086 (rank : 111)	θ value	4.03905 (rank : 89)
Query Neighborhood Hits	135	Target Neighborhood Hits	141	Shared Neighborhood Hits	14
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

MYPT2_HUMAN
NC score	0.015693 (rank : 112)	θ value	1.06291 (rank : 53)
Query Neighborhood Hits	135	Target Neighborhood Hits	707	Shared Neighborhood Hits	37
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

RYBP_MOUSE
NC score	0.015659 (rank : 113)	θ value	6.88961 (rank : 113)
Query Neighborhood Hits	135	Target Neighborhood Hits	39	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CCI5, Q9WVK2	Gene names	Rybp, Dedaf
Domain Architecture	No domain graphic available
Description	RING1 and YY1-binding protein (Death effector domain-associated factor) (DED-associated factor).

PACN2_MOUSE
NC score	0.015607 (rank : 114)	θ value	6.88961 (rank : 110)
Query Neighborhood Hits	135	Target Neighborhood Hits	382	Shared Neighborhood Hits	20
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

NRX3B_HUMAN
NC score	0.015586 (rank : 115)	θ value	4.03905 (rank : 84)
Query Neighborhood Hits	135	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HDB5	Gene names	NRXN3, KIAA0743
Domain Architecture	No domain graphic available
Description	Neurexin-3-beta precursor (Neurexin III-beta).

K1H1_HUMAN
NC score	0.015263 (rank : 116)	θ value	3.0926 (rank : 78)
Query Neighborhood Hits	135	Target Neighborhood Hits	433	Shared Neighborhood Hits	26
SwissProt Accessions	Q15323	Gene names	KRTHA1, HHA1, HKA1
Domain Architecture
Description	Keratin, type I cuticular Ha1 (Hair keratin, type I Ha1).

TITIN_HUMAN
NC score	0.014963 (rank : 117)	θ value	0.0961366 (rank : 14)
Query Neighborhood Hits	135	Target Neighborhood Hits	2923	Shared Neighborhood Hits	64
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

STK10_MOUSE
NC score	0.014672 (rank : 118)	θ value	0.21417 (rank : 19)
Query Neighborhood Hits	135	Target Neighborhood Hits	2132	Shared Neighborhood Hits	62
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

MCM3_HUMAN
NC score	0.014556 (rank : 119)	θ value	5.27518 (rank : 94)
Query Neighborhood Hits	135	Target Neighborhood Hits	87	Shared Neighborhood Hits	17
SwissProt Accessions	P25205, Q92660, Q9BTR3, Q9NUE7	Gene names	MCM3
Domain Architecture
Description	DNA replication licensing factor MCM3 (DNA polymerase alpha holoenzyme-associated protein P1) (RLF subunit beta) (P102 protein) (P1-MCM3).

K1C16_HUMAN
NC score	0.013967 (rank : 120)	θ value	0.47712 (rank : 31)
Query Neighborhood Hits	135	Target Neighborhood Hits	440	Shared Neighborhood Hits	26
SwissProt Accessions	P08779, P30654, Q16402, Q9UBG8	Gene names	KRT16, KRT16A
Domain Architecture
Description	Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16).

BCCIP_HUMAN
NC score	0.013342 (rank : 121)	θ value	8.99809 (rank : 122)
Query Neighborhood Hits	135	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q9P287, Q8ND15, Q96GC4, Q9P288	Gene names	BCCIP, TOK1
Domain Architecture	No domain graphic available
Description	BRCA2 and CDKN1A-interacting protein (Protein TOK-1).

PHLPP_HUMAN
NC score	0.011905 (rank : 122)	θ value	1.81305 (rank : 68)
Query Neighborhood Hits	135	Target Neighborhood Hits	604	Shared Neighborhood Hits	10
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

STK10_HUMAN
NC score	0.011829 (rank : 123)	θ value	1.38821 (rank : 62)
Query Neighborhood Hits	135	Target Neighborhood Hits	1921	Shared Neighborhood Hits	49
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

GHR_MOUSE
NC score	0.011632 (rank : 124)	θ value	6.88961 (rank : 104)
Query Neighborhood Hits	135	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	P16882, P16590, Q61653, Q6DI66, Q80W86, Q8R1M5, Q920Z3, Q9R264	Gene names	Ghr
Domain Architecture
Description	Growth hormone receptor precursor (GH receptor) (Somatotropin receptor) [Contains: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)].

ATF6B_HUMAN
NC score	0.010989 (rank : 125)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	135	Target Neighborhood Hits	122	Shared Neighborhood Hits	5
SwissProt Accessions	Q99941, Q13269, Q14343, Q14345, Q99635, Q99637, Q9H3V9, Q9H3W1, Q9NPL0	Gene names	CREBL1, G13
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp) (Protein G13).

CS021_MOUSE
NC score	0.010791 (rank : 126)	θ value	8.99809 (rank : 124)
Query Neighborhood Hits	135	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D279, Q3UI04	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf21 homolog.

BRD9_MOUSE
NC score	0.010605 (rank : 127)	θ value	5.27518 (rank : 92)
Query Neighborhood Hits	135	Target Neighborhood Hits	84	Shared Neighborhood Hits	7
SwissProt Accessions	Q3UQU0, Q5FWH1, Q811F7	Gene names	Brd9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9.

PHLPP_MOUSE
NC score	0.010073 (rank : 128)	θ value	3.0926 (rank : 79)
Query Neighborhood Hits	135	Target Neighborhood Hits	394	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CHE4, Q6PCN0, Q8QZU8, Q8R5E5, Q99KL6	Gene names	Phlpp, Kiaa0606, Plekhe1, Scop
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein).

RAG2_MOUSE
NC score	0.009672 (rank : 129)	θ value	8.99809 (rank : 134)
Query Neighborhood Hits	135	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	P21784	Gene names	Rag2, Rag-2
Domain Architecture
Description	V(D)J recombination-activating protein 2 (RAG-2).

NRX3A_HUMAN
NC score	0.009331 (rank : 130)	θ value	4.03905 (rank : 83)
Query Neighborhood Hits	135	Target Neighborhood Hits	164	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

SL9A3_HUMAN
NC score	0.008992 (rank : 131)	θ value	5.27518 (rank : 98)
Query Neighborhood Hits	135	Target Neighborhood Hits	63	Shared Neighborhood Hits	5
SwissProt Accessions	P48764	Gene names	SLC9A3, NHE3
Domain Architecture
Description	Sodium/hydrogen exchanger 3 (Na(+)/H(+) exchanger 3) (NHE-3) (Solute carrier family 9 member 3).

OSBL8_HUMAN
NC score	0.007455 (rank : 132)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	135	Target Neighborhood Hits	289	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

CD2L5_MOUSE
NC score	0.007030 (rank : 133)	θ value	0.813845 (rank : 43)
Query Neighborhood Hits	135	Target Neighborhood Hits	1011	Shared Neighborhood Hits	24
SwissProt Accessions	Q69ZA1, Q80V11, Q8BZG1, Q8K0A4	Gene names	Cdc2l5, Kiaa1791
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5).

DYRK4_HUMAN
NC score	0.006519 (rank : 134)	θ value	2.36792 (rank : 72)
Query Neighborhood Hits	135	Target Neighborhood Hits	750	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NR20, Q8NEF2, Q92631	Gene names	DYRK4
Domain Architecture	No domain graphic available
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 4 (EC 2.7.12.1).

DCX_HUMAN
NC score	0.006237 (rank : 135)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	135	Target Neighborhood Hits	141	Shared Neighborhood Hits	5
SwissProt Accessions	O43602, O43911	Gene names	DCX, DBCN, LISX
Domain Architecture
Description	Neuronal migration protein doublecortin (Lissencephalin-X) (Lis-X) (Doublin).

SSH1_HUMAN
NC score	0.005949 (rank : 136)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	135	Target Neighborhood Hits	164	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WYL5, Q6P6C0, Q8N9A7, Q8WYL3, Q8WYL4, Q9P2P8	Gene names	SSH1, KIAA1298, SSH1L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (hSSH-1L).

SPAST_HUMAN
NC score	0.004693 (rank : 137)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	135	Target Neighborhood Hits	100	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UBP0, Q9UPR9	Gene names	SPAST, KIAA1083, SPG4
Domain Architecture
Description	Spastin.

PRKX_HUMAN
NC score	0.002470 (rank : 138)	θ value	6.88961 (rank : 111)
Query Neighborhood Hits	135	Target Neighborhood Hits	847	Shared Neighborhood Hits	9
SwissProt Accessions	P51817	Gene names	PRKX, PKX1
Domain Architecture
Description	Serine/threonine-protein kinase PRKX (EC 2.7.11.1) (Protein kinase PKX1).

PEG3_HUMAN
NC score	0.000586 (rank : 139)	θ value	4.03905 (rank : 85)
Query Neighborhood Hits	135	Target Neighborhood Hits	800	Shared Neighborhood Hits	10
SwissProt Accessions	Q9GZU2, P78418, Q5H9P9, Q7Z7H7, Q8TF75, Q9GZY2	Gene names	PEG3, KIAA0287
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein.

ZIM2_HUMAN
NC score	0.000055 (rank : 140)	θ value	2.36792 (rank : 77)
Query Neighborhood Hits	135	Target Neighborhood Hits	718	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZV7	Gene names	ZIM2
Domain Architecture
Description	Zinc finger imprinted 2.