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Network neighborhood for query Sequence : K0146_HUMAN

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K0146_HUMAN
SwissProt Accessions	Q14159, Q96BI5	Gene names	KIAA0146
Domain Architecture	No domain graphic available
Description	Protein KIAA0146.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

K0146_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	48	Target Neighborhood Hits	48	Shared Neighborhood Hits	48
SwissProt Accessions	Q14159, Q96BI5	Gene names	KIAA0146
Domain Architecture	No domain graphic available
Description	Protein KIAA0146.

K0146_MOUSE
θ value	0 (rank : 2)	NC score	0.961982 (rank : 2)
Query Neighborhood Hits	48	Target Neighborhood Hits	57	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BGX7, Q3TCD0, Q5U457, Q6A0B6, Q6IS60, Q811E1, Q8BWD6, Q8R305	Gene names	Kiaa0146
Domain Architecture	No domain graphic available
Description	Protein KIAA0146.

DSPP_MOUSE
θ value	0.00134147 (rank : 3)	NC score	0.122963 (rank : 3)
Query Neighborhood Hits	48	Target Neighborhood Hits	491	Shared Neighborhood Hits	14
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

MYT1_HUMAN
θ value	0.00228821 (rank : 4)	NC score	0.062358 (rank : 6)
Query Neighborhood Hits	48	Target Neighborhood Hits	475	Shared Neighborhood Hits	8
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

DSPP_HUMAN
θ value	0.0113563 (rank : 5)	NC score	0.089373 (rank : 4)
Query Neighborhood Hits	48	Target Neighborhood Hits	645	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

TOP2A_HUMAN
θ value	0.0736092 (rank : 6)	NC score	0.047750 (rank : 12)
Query Neighborhood Hits	48	Target Neighborhood Hits	135	Shared Neighborhood Hits	5
SwissProt Accessions	P11388, Q71UN1, Q9HB24, Q9HB25, Q9HB26, Q9UP44, Q9UQP9	Gene names	TOP2A, TOP2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

WDFY3_HUMAN
θ value	0.0736092 (rank : 7)	NC score	0.059781 (rank : 7)
Query Neighborhood Hits	48	Target Neighborhood Hits	348	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IZQ1, Q4W5K5, Q6P0Q5, Q8N1T2, Q96BS7, Q96N85, Q9Y2J7	Gene names	WDFY3, KIAA0993
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy).

WDFY3_MOUSE
θ value	0.0961366 (rank : 8)	NC score	0.059319 (rank : 8)
Query Neighborhood Hits	48	Target Neighborhood Hits	332	Shared Neighborhood Hits	8
SwissProt Accessions	Q6VNB8, Q8C8H7	Gene names	Wdfy3
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Beach domain, WD repeat and FYVE domain-containing protein 1) (BWF1).

MYCPP_HUMAN
θ value	0.125558 (rank : 9)	NC score	0.051586 (rank : 9)
Query Neighborhood Hits	48	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z401, Q14655, Q86T77, Q8IVX2, Q8NB93	Gene names	MYCPBP, IRLB
Domain Architecture	No domain graphic available
Description	C-myc promoter-binding protein.

DMD_HUMAN
θ value	0.163984 (rank : 10)	NC score	0.029187 (rank : 21)
Query Neighborhood Hits	48	Target Neighborhood Hits	1135	Shared Neighborhood Hits	7
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

DMD_MOUSE
θ value	0.163984 (rank : 11)	NC score	0.027345 (rank : 22)
Query Neighborhood Hits	48	Target Neighborhood Hits	1111	Shared Neighborhood Hits	4
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

IWS1_HUMAN
θ value	0.163984 (rank : 12)	NC score	0.048890 (rank : 10)
Query Neighborhood Hits	48	Target Neighborhood Hits	1241	Shared Neighborhood Hits	16
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

ALMS1_MOUSE
θ value	0.47712 (rank : 13)	NC score	0.044151 (rank : 13)
Query Neighborhood Hits	48	Target Neighborhood Hits	181	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K4E0, Q6A084, Q8C9N9	Gene names	Alms1, Kiaa0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1 homolog.

ZCH10_MOUSE
θ value	0.47712 (rank : 14)	NC score	0.078192 (rank : 5)
Query Neighborhood Hits	48	Target Neighborhood Hits	133	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CX48	Gene names	Zcchc10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

WDR60_HUMAN
θ value	0.62314 (rank : 15)	NC score	0.038493 (rank : 15)
Query Neighborhood Hits	48	Target Neighborhood Hits	286	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WVS4, Q9NW58	Gene names	WDR60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

CHD6_HUMAN
θ value	1.06291 (rank : 16)	NC score	0.017908 (rank : 30)
Query Neighborhood Hits	48	Target Neighborhood Hits	342	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

ASXL1_MOUSE
θ value	1.38821 (rank : 17)	NC score	0.038792 (rank : 14)
Query Neighborhood Hits	48	Target Neighborhood Hits	182	Shared Neighborhood Hits	6
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

SAMN1_MOUSE
θ value	1.38821 (rank : 18)	NC score	0.030044 (rank : 20)
Query Neighborhood Hits	48	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	P57725, Q8C6S2	Gene names	Samsn1
Domain Architecture
Description	SAM domain-containing protein SAMSN-1 (SAM domain, SH3 domain and nuclear localization signals protein 1).

DEPD5_MOUSE
θ value	1.81305 (rank : 19)	NC score	0.031095 (rank : 19)
Query Neighborhood Hits	48	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	P61460	Gene names	Depdc5, Kiaa0645
Domain Architecture
Description	DEP domain-containing protein 5.

MAST3_HUMAN
θ value	1.81305 (rank : 20)	NC score	0.005493 (rank : 43)
Query Neighborhood Hits	48	Target Neighborhood Hits	1128	Shared Neighborhood Hits	8
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

BOP1_HUMAN
θ value	2.36792 (rank : 21)	NC score	0.023324 (rank : 25)
Query Neighborhood Hits	48	Target Neighborhood Hits	257	Shared Neighborhood Hits	4
SwissProt Accessions	Q14137, Q969Z6, Q96IS8, Q9BSA7, Q9BVM0	Gene names	BOP1, KIAA0124
Domain Architecture
Description	Ribosome biogenesis protein BOP1 (Block of proliferation 1 protein).

BPTF_HUMAN
θ value	2.36792 (rank : 22)	NC score	0.023990 (rank : 24)
Query Neighborhood Hits	48	Target Neighborhood Hits	786	Shared Neighborhood Hits	10
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

CSKP_HUMAN
θ value	2.36792 (rank : 23)	NC score	0.006681 (rank : 39)
Query Neighborhood Hits	48	Target Neighborhood Hits	1022	Shared Neighborhood Hits	6
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

CSKP_MOUSE
θ value	2.36792 (rank : 24)	NC score	0.006792 (rank : 38)
Query Neighborhood Hits	48	Target Neighborhood Hits	1027	Shared Neighborhood Hits	7
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

LPXN_MOUSE
θ value	2.36792 (rank : 25)	NC score	0.012455 (rank : 32)
Query Neighborhood Hits	48	Target Neighborhood Hits	227	Shared Neighborhood Hits	3
SwissProt Accessions	Q99N69	Gene names	Lpxn
Domain Architecture	No domain graphic available
Description	Leupaxin.

NUCL_MOUSE
θ value	3.0926 (rank : 26)	NC score	0.018538 (rank : 27)
Query Neighborhood Hits	48	Target Neighborhood Hits	425	Shared Neighborhood Hits	8
SwissProt Accessions	P09405, Q548M9, Q61991, Q99K50	Gene names	Ncl, Nuc
Domain Architecture
Description	Nucleolin (Protein C23).

PRGR_MOUSE
θ value	3.0926 (rank : 27)	NC score	0.009612 (rank : 36)
Query Neighborhood Hits	48	Target Neighborhood Hits	286	Shared Neighborhood Hits	2
SwissProt Accessions	Q00175	Gene names	Pgr, Nr3c3, Pr
Domain Architecture
Description	Progesterone receptor (PR).

ZN622_HUMAN
θ value	3.0926 (rank : 28)	NC score	0.031147 (rank : 17)
Query Neighborhood Hits	48	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q969S3	Gene names	ZNF622, ZPR9
Domain Architecture	No domain graphic available
Description	Zinc finger protein 622 (Zinc finger-like protein 9).

DIAP1_MOUSE
θ value	4.03905 (rank : 29)	NC score	0.009662 (rank : 35)
Query Neighborhood Hits	48	Target Neighborhood Hits	839	Shared Neighborhood Hits	3
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

PDE4D_HUMAN
θ value	4.03905 (rank : 30)	NC score	0.009722 (rank : 34)
Query Neighborhood Hits	48	Target Neighborhood Hits	122	Shared Neighborhood Hits	4
SwissProt Accessions	Q08499, O43433, Q13549, Q13550, Q13551, Q7Z2L8, Q8IV84, Q8IVA9, Q8IVD2, Q8IVD3, Q9HCX7	Gene names	PDE4D
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4D (EC 3.1.4.17) (DPDE3) (PDE43).

PZRN3_MOUSE
θ value	4.03905 (rank : 31)	NC score	0.017936 (rank : 29)
Query Neighborhood Hits	48	Target Neighborhood Hits	447	Shared Neighborhood Hits	9
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

SLC2B_HUMAN
θ value	4.03905 (rank : 32)	NC score	0.033209 (rank : 16)
Query Neighborhood Hits	48	Target Neighborhood Hits	214	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NEV8, Q9Y4D6	Gene names	EXPH5, KIAA0624, SLAC2B
Domain Architecture	No domain graphic available
Description	Slp homolog lacking C2 domains b (Exophilin-5).

M4K5_MOUSE
θ value	5.27518 (rank : 33)	NC score	0.004553 (rank : 44)
Query Neighborhood Hits	48	Target Neighborhood Hits	839	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BPM2, Q6PEQ2, Q8C3U5, Q8CGF3, Q99LM7, Q9CX73	Gene names	Map4k5
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5).

PZRN3_HUMAN
θ value	5.27518 (rank : 34)	NC score	0.018405 (rank : 28)
Query Neighborhood Hits	48	Target Neighborhood Hits	461	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

ZEP1_MOUSE
θ value	5.27518 (rank : 35)	NC score	0.006608 (rank : 40)
Query Neighborhood Hits	48	Target Neighborhood Hits	1063	Shared Neighborhood Hits	7
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

ZFY2_MOUSE
θ value	5.27518 (rank : 36)	NC score	0.001369 (rank : 48)
Query Neighborhood Hits	48	Target Neighborhood Hits	795	Shared Neighborhood Hits	6
SwissProt Accessions	P20662	Gene names	Zfy2, Zfy-2
Domain Architecture
Description	Zinc finger Y-chromosomal protein 2.

ANK3_HUMAN
θ value	6.88961 (rank : 37)	NC score	0.005830 (rank : 42)
Query Neighborhood Hits	48	Target Neighborhood Hits	853	Shared Neighborhood Hits	9
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

CEP72_MOUSE
θ value	6.88961 (rank : 38)	NC score	0.013427 (rank : 31)
Query Neighborhood Hits	48	Target Neighborhood Hits	381	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D3R3, Q8BM53, Q9D0B7	Gene names	Cep72
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 72 kDa (Cep72 protein).

HILS1_HUMAN
θ value	6.88961 (rank : 39)	NC score	0.023993 (rank : 23)
Query Neighborhood Hits	48	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	P60008	Gene names	HILS1
Domain Architecture	No domain graphic available
Description	Spermatid-specific linker histone H1-like protein.

KAISO_HUMAN
θ value	6.88961 (rank : 40)	NC score	0.003017 (rank : 45)
Query Neighborhood Hits	48	Target Neighborhood Hits	840	Shared Neighborhood Hits	5
SwissProt Accessions	Q86T24, O00319, Q7Z361, Q8IVP6, Q8N3P0	Gene names	ZBTB33, KAISO, ZNF348
Domain Architecture	No domain graphic available
Description	Transcriptional regulator Kaiso (Zinc finger and BTB domain-containing protein 33).

RM21_HUMAN
θ value	6.88961 (rank : 41)	NC score	0.023323 (rank : 26)
Query Neighborhood Hits	48	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z2W9	Gene names	MRPL21
Domain Architecture	No domain graphic available
Description	39S ribosomal protein L21, mitochondrial precursor (L21mt) (MRP-L21).

RSF1_HUMAN
θ value	6.88961 (rank : 42)	NC score	0.048854 (rank : 11)
Query Neighborhood Hits	48	Target Neighborhood Hits	539	Shared Neighborhood Hits	10
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

TRI26_HUMAN
θ value	6.88961 (rank : 43)	NC score	0.006019 (rank : 41)
Query Neighborhood Hits	48	Target Neighborhood Hits	335	Shared Neighborhood Hits	4
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

CUBN_MOUSE
θ value	8.99809 (rank : 44)	NC score	0.002962 (rank : 46)
Query Neighborhood Hits	48	Target Neighborhood Hits	477	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

DSC3_MOUSE
θ value	8.99809 (rank : 45)	NC score	0.002956 (rank : 47)
Query Neighborhood Hits	48	Target Neighborhood Hits	154	Shared Neighborhood Hits	2
SwissProt Accessions	P55850, O55110, O55122	Gene names	Dsc3
Domain Architecture
Description	Desmocollin-3 precursor.

HTSF1_HUMAN
θ value	8.99809 (rank : 46)	NC score	0.031128 (rank : 18)
Query Neighborhood Hits	48	Target Neighborhood Hits	408	Shared Neighborhood Hits	9
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

NF2L1_MOUSE
θ value	8.99809 (rank : 47)	NC score	0.009422 (rank : 37)
Query Neighborhood Hits	48	Target Neighborhood Hits	185	Shared Neighborhood Hits	2
SwissProt Accessions	Q61985, O70234	Gene names	Nfe2l1, Nrf1
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1).

RFIP5_MOUSE
θ value	8.99809 (rank : 48)	NC score	0.011851 (rank : 33)
Query Neighborhood Hits	48	Target Neighborhood Hits	126	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R361	Gene names	Rab11fip5, D6Ertd32e, Rip11
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 5 (Rab11-FIP5) (Rab11-interacting protein Rip11).

Hits sorted by NC score

K0146_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	48	Target Neighborhood Hits	48	Shared Neighborhood Hits	48
SwissProt Accessions	Q14159, Q96BI5	Gene names	KIAA0146
Domain Architecture	No domain graphic available
Description	Protein KIAA0146.

K0146_MOUSE
NC score	0.961982 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	48	Target Neighborhood Hits	57	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BGX7, Q3TCD0, Q5U457, Q6A0B6, Q6IS60, Q811E1, Q8BWD6, Q8R305	Gene names	Kiaa0146
Domain Architecture	No domain graphic available
Description	Protein KIAA0146.

DSPP_MOUSE
NC score	0.122963 (rank : 3)	θ value	0.00134147 (rank : 3)
Query Neighborhood Hits	48	Target Neighborhood Hits	491	Shared Neighborhood Hits	14
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

DSPP_HUMAN
NC score	0.089373 (rank : 4)	θ value	0.0113563 (rank : 5)
Query Neighborhood Hits	48	Target Neighborhood Hits	645	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

ZCH10_MOUSE
NC score	0.078192 (rank : 5)	θ value	0.47712 (rank : 14)
Query Neighborhood Hits	48	Target Neighborhood Hits	133	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CX48	Gene names	Zcchc10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

MYT1_HUMAN
NC score	0.062358 (rank : 6)	θ value	0.00228821 (rank : 4)
Query Neighborhood Hits	48	Target Neighborhood Hits	475	Shared Neighborhood Hits	8
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

WDFY3_HUMAN
NC score	0.059781 (rank : 7)	θ value	0.0736092 (rank : 7)
Query Neighborhood Hits	48	Target Neighborhood Hits	348	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IZQ1, Q4W5K5, Q6P0Q5, Q8N1T2, Q96BS7, Q96N85, Q9Y2J7	Gene names	WDFY3, KIAA0993
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy).

WDFY3_MOUSE
NC score	0.059319 (rank : 8)	θ value	0.0961366 (rank : 8)
Query Neighborhood Hits	48	Target Neighborhood Hits	332	Shared Neighborhood Hits	8
SwissProt Accessions	Q6VNB8, Q8C8H7	Gene names	Wdfy3
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Beach domain, WD repeat and FYVE domain-containing protein 1) (BWF1).

MYCPP_HUMAN
NC score	0.051586 (rank : 9)	θ value	0.125558 (rank : 9)
Query Neighborhood Hits	48	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z401, Q14655, Q86T77, Q8IVX2, Q8NB93	Gene names	MYCPBP, IRLB
Domain Architecture	No domain graphic available
Description	C-myc promoter-binding protein.

IWS1_HUMAN
NC score	0.048890 (rank : 10)	θ value	0.163984 (rank : 12)
Query Neighborhood Hits	48	Target Neighborhood Hits	1241	Shared Neighborhood Hits	16
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

RSF1_HUMAN
NC score	0.048854 (rank : 11)	θ value	6.88961 (rank : 42)
Query Neighborhood Hits	48	Target Neighborhood Hits	539	Shared Neighborhood Hits	10
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

TOP2A_HUMAN
NC score	0.047750 (rank : 12)	θ value	0.0736092 (rank : 6)
Query Neighborhood Hits	48	Target Neighborhood Hits	135	Shared Neighborhood Hits	5
SwissProt Accessions	P11388, Q71UN1, Q9HB24, Q9HB25, Q9HB26, Q9UP44, Q9UQP9	Gene names	TOP2A, TOP2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

ALMS1_MOUSE
NC score	0.044151 (rank : 13)	θ value	0.47712 (rank : 13)
Query Neighborhood Hits	48	Target Neighborhood Hits	181	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K4E0, Q6A084, Q8C9N9	Gene names	Alms1, Kiaa0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1 homolog.

ASXL1_MOUSE
NC score	0.038792 (rank : 14)	θ value	1.38821 (rank : 17)
Query Neighborhood Hits	48	Target Neighborhood Hits	182	Shared Neighborhood Hits	6
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

WDR60_HUMAN
NC score	0.038493 (rank : 15)	θ value	0.62314 (rank : 15)
Query Neighborhood Hits	48	Target Neighborhood Hits	286	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WVS4, Q9NW58	Gene names	WDR60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

SLC2B_HUMAN
NC score	0.033209 (rank : 16)	θ value	4.03905 (rank : 32)
Query Neighborhood Hits	48	Target Neighborhood Hits	214	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NEV8, Q9Y4D6	Gene names	EXPH5, KIAA0624, SLAC2B
Domain Architecture	No domain graphic available
Description	Slp homolog lacking C2 domains b (Exophilin-5).

ZN622_HUMAN
NC score	0.031147 (rank : 17)	θ value	3.0926 (rank : 28)
Query Neighborhood Hits	48	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q969S3	Gene names	ZNF622, ZPR9
Domain Architecture	No domain graphic available
Description	Zinc finger protein 622 (Zinc finger-like protein 9).

HTSF1_HUMAN
NC score	0.031128 (rank : 18)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	48	Target Neighborhood Hits	408	Shared Neighborhood Hits	9
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

DEPD5_MOUSE
NC score	0.031095 (rank : 19)	θ value	1.81305 (rank : 19)
Query Neighborhood Hits	48	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	P61460	Gene names	Depdc5, Kiaa0645
Domain Architecture
Description	DEP domain-containing protein 5.

SAMN1_MOUSE
NC score	0.030044 (rank : 20)	θ value	1.38821 (rank : 18)
Query Neighborhood Hits	48	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	P57725, Q8C6S2	Gene names	Samsn1
Domain Architecture
Description	SAM domain-containing protein SAMSN-1 (SAM domain, SH3 domain and nuclear localization signals protein 1).

DMD_HUMAN
NC score	0.029187 (rank : 21)	θ value	0.163984 (rank : 10)
Query Neighborhood Hits	48	Target Neighborhood Hits	1135	Shared Neighborhood Hits	7
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

DMD_MOUSE
NC score	0.027345 (rank : 22)	θ value	0.163984 (rank : 11)
Query Neighborhood Hits	48	Target Neighborhood Hits	1111	Shared Neighborhood Hits	4
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

HILS1_HUMAN
NC score	0.023993 (rank : 23)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	48	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	P60008	Gene names	HILS1
Domain Architecture	No domain graphic available
Description	Spermatid-specific linker histone H1-like protein.

BPTF_HUMAN
NC score	0.023990 (rank : 24)	θ value	2.36792 (rank : 22)
Query Neighborhood Hits	48	Target Neighborhood Hits	786	Shared Neighborhood Hits	10
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

BOP1_HUMAN
NC score	0.023324 (rank : 25)	θ value	2.36792 (rank : 21)
Query Neighborhood Hits	48	Target Neighborhood Hits	257	Shared Neighborhood Hits	4
SwissProt Accessions	Q14137, Q969Z6, Q96IS8, Q9BSA7, Q9BVM0	Gene names	BOP1, KIAA0124
Domain Architecture
Description	Ribosome biogenesis protein BOP1 (Block of proliferation 1 protein).

RM21_HUMAN
NC score	0.023323 (rank : 26)	θ value	6.88961 (rank : 41)
Query Neighborhood Hits	48	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z2W9	Gene names	MRPL21
Domain Architecture	No domain graphic available
Description	39S ribosomal protein L21, mitochondrial precursor (L21mt) (MRP-L21).

NUCL_MOUSE
NC score	0.018538 (rank : 27)	θ value	3.0926 (rank : 26)
Query Neighborhood Hits	48	Target Neighborhood Hits	425	Shared Neighborhood Hits	8
SwissProt Accessions	P09405, Q548M9, Q61991, Q99K50	Gene names	Ncl, Nuc
Domain Architecture
Description	Nucleolin (Protein C23).

PZRN3_HUMAN
NC score	0.018405 (rank : 28)	θ value	5.27518 (rank : 34)
Query Neighborhood Hits	48	Target Neighborhood Hits	461	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_MOUSE
NC score	0.017936 (rank : 29)	θ value	4.03905 (rank : 31)
Query Neighborhood Hits	48	Target Neighborhood Hits	447	Shared Neighborhood Hits	9
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

CHD6_HUMAN
NC score	0.017908 (rank : 30)	θ value	1.06291 (rank : 16)
Query Neighborhood Hits	48	Target Neighborhood Hits	342	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

CEP72_MOUSE
NC score	0.013427 (rank : 31)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	48	Target Neighborhood Hits	381	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D3R3, Q8BM53, Q9D0B7	Gene names	Cep72
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 72 kDa (Cep72 protein).

LPXN_MOUSE
NC score	0.012455 (rank : 32)	θ value	2.36792 (rank : 25)
Query Neighborhood Hits	48	Target Neighborhood Hits	227	Shared Neighborhood Hits	3
SwissProt Accessions	Q99N69	Gene names	Lpxn
Domain Architecture	No domain graphic available
Description	Leupaxin.

RFIP5_MOUSE
NC score	0.011851 (rank : 33)	θ value	8.99809 (rank : 48)
Query Neighborhood Hits	48	Target Neighborhood Hits	126	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R361	Gene names	Rab11fip5, D6Ertd32e, Rip11
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 5 (Rab11-FIP5) (Rab11-interacting protein Rip11).

PDE4D_HUMAN
NC score	0.009722 (rank : 34)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	48	Target Neighborhood Hits	122	Shared Neighborhood Hits	4
SwissProt Accessions	Q08499, O43433, Q13549, Q13550, Q13551, Q7Z2L8, Q8IV84, Q8IVA9, Q8IVD2, Q8IVD3, Q9HCX7	Gene names	PDE4D
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4D (EC 3.1.4.17) (DPDE3) (PDE43).

DIAP1_MOUSE
NC score	0.009662 (rank : 35)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	48	Target Neighborhood Hits	839	Shared Neighborhood Hits	3
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

PRGR_MOUSE
NC score	0.009612 (rank : 36)	θ value	3.0926 (rank : 27)
Query Neighborhood Hits	48	Target Neighborhood Hits	286	Shared Neighborhood Hits	2
SwissProt Accessions	Q00175	Gene names	Pgr, Nr3c3, Pr
Domain Architecture
Description	Progesterone receptor (PR).

NF2L1_MOUSE
NC score	0.009422 (rank : 37)	θ value	8.99809 (rank : 47)
Query Neighborhood Hits	48	Target Neighborhood Hits	185	Shared Neighborhood Hits	2
SwissProt Accessions	Q61985, O70234	Gene names	Nfe2l1, Nrf1
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1).

CSKP_MOUSE
NC score	0.006792 (rank : 38)	θ value	2.36792 (rank : 24)
Query Neighborhood Hits	48	Target Neighborhood Hits	1027	Shared Neighborhood Hits	7
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

CSKP_HUMAN
NC score	0.006681 (rank : 39)	θ value	2.36792 (rank : 23)
Query Neighborhood Hits	48	Target Neighborhood Hits	1022	Shared Neighborhood Hits	6
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

ZEP1_MOUSE
NC score	0.006608 (rank : 40)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	48	Target Neighborhood Hits	1063	Shared Neighborhood Hits	7
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

TRI26_HUMAN
NC score	0.006019 (rank : 41)	θ value	6.88961 (rank : 43)
Query Neighborhood Hits	48	Target Neighborhood Hits	335	Shared Neighborhood Hits	4
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

ANK3_HUMAN
NC score	0.005830 (rank : 42)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	48	Target Neighborhood Hits	853	Shared Neighborhood Hits	9
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

MAST3_HUMAN
NC score	0.005493 (rank : 43)	θ value	1.81305 (rank : 20)
Query Neighborhood Hits	48	Target Neighborhood Hits	1128	Shared Neighborhood Hits	8
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

M4K5_MOUSE
NC score	0.004553 (rank : 44)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	48	Target Neighborhood Hits	839	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BPM2, Q6PEQ2, Q8C3U5, Q8CGF3, Q99LM7, Q9CX73	Gene names	Map4k5
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5).

KAISO_HUMAN
NC score	0.003017 (rank : 45)	θ value	6.88961 (rank : 40)
Query Neighborhood Hits	48	Target Neighborhood Hits	840	Shared Neighborhood Hits	5
SwissProt Accessions	Q86T24, O00319, Q7Z361, Q8IVP6, Q8N3P0	Gene names	ZBTB33, KAISO, ZNF348
Domain Architecture	No domain graphic available
Description	Transcriptional regulator Kaiso (Zinc finger and BTB domain-containing protein 33).

CUBN_MOUSE
NC score	0.002962 (rank : 46)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	48	Target Neighborhood Hits	477	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

DSC3_MOUSE
NC score	0.002956 (rank : 47)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	48	Target Neighborhood Hits	154	Shared Neighborhood Hits	2
SwissProt Accessions	P55850, O55110, O55122	Gene names	Dsc3
Domain Architecture
Description	Desmocollin-3 precursor.

ZFY2_MOUSE
NC score	0.001369 (rank : 48)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	48	Target Neighborhood Hits	795	Shared Neighborhood Hits	6
SwissProt Accessions	P20662	Gene names	Zfy2, Zfy-2
Domain Architecture
Description	Zinc finger Y-chromosomal protein 2.