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Network neighborhood for query Sequence : CS021_HUMAN

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CS021_HUMAN
SwissProt Accessions	Q8IVT2	Gene names	C19orf21
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf21.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CS021_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	98	Target Neighborhood Hits	98	Shared Neighborhood Hits	98
SwissProt Accessions	Q8IVT2	Gene names	C19orf21
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf21.

CS021_MOUSE
θ value	0 (rank : 2)	NC score	0.948204 (rank : 2)
Query Neighborhood Hits	98	Target Neighborhood Hits	47	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D279, Q3UI04	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf21 homolog.

AKAP2_HUMAN
θ value	0.00035302 (rank : 3)	NC score	0.171412 (rank : 3)
Query Neighborhood Hits	98	Target Neighborhood Hits	507	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

MYO15_MOUSE
θ value	0.00665767 (rank : 4)	NC score	0.035260 (rank : 26)
Query Neighborhood Hits	98	Target Neighborhood Hits	467	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

AKAP2_MOUSE
θ value	0.0252991 (rank : 5)	NC score	0.130171 (rank : 4)
Query Neighborhood Hits	98	Target Neighborhood Hits	385	Shared Neighborhood Hits	14
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

ROBO3_HUMAN
θ value	0.0252991 (rank : 6)	NC score	0.024732 (rank : 48)
Query Neighborhood Hits	98	Target Neighborhood Hits	570	Shared Neighborhood Hits	12
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

CHD4_MOUSE
θ value	0.0431538 (rank : 7)	NC score	0.034983 (rank : 27)
Query Neighborhood Hits	98	Target Neighborhood Hits	408	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CBP_HUMAN
θ value	0.365318 (rank : 8)	NC score	0.058997 (rank : 5)
Query Neighborhood Hits	98	Target Neighborhood Hits	941	Shared Neighborhood Hits	41
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

LIMD1_HUMAN
θ value	0.47712 (rank : 9)	NC score	0.028332 (rank : 40)
Query Neighborhood Hits	98	Target Neighborhood Hits	201	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UGP4, Q9BQQ9, Q9NQ47	Gene names	LIMD1
Domain Architecture
Description	LIM domain-containing protein 1.

ACK1_MOUSE
θ value	0.62314 (rank : 10)	NC score	0.011117 (rank : 88)
Query Neighborhood Hits	98	Target Neighborhood Hits	1080	Shared Neighborhood Hits	28
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

MAGI2_HUMAN
θ value	0.62314 (rank : 11)	NC score	0.023918 (rank : 51)
Query Neighborhood Hits	98	Target Neighborhood Hits	373	Shared Neighborhood Hits	9
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

PRG4_HUMAN
θ value	0.62314 (rank : 12)	NC score	0.040646 (rank : 21)
Query Neighborhood Hits	98	Target Neighborhood Hits	764	Shared Neighborhood Hits	30
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

WNK2_HUMAN
θ value	0.62314 (rank : 13)	NC score	0.016136 (rank : 74)
Query Neighborhood Hits	98	Target Neighborhood Hits	1407	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

DIP2A_HUMAN
θ value	0.813845 (rank : 14)	NC score	0.034624 (rank : 28)
Query Neighborhood Hits	98	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	Q14689, Q8IVA3, Q8N4S2, Q8TD89, Q96ML9	Gene names	DIP2A, C21orf106, DIP2, KIAA0184
Domain Architecture
Description	Disco-interacting protein 2 homolog A.

AN13D_HUMAN
θ value	1.06291 (rank : 15)	NC score	0.027828 (rank : 42)
Query Neighborhood Hits	98	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZTN6, Q6ZVD0, Q86SU1	Gene names	ANKRD13D
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13D.

ANK2_HUMAN
θ value	1.06291 (rank : 16)	NC score	0.021965 (rank : 53)
Query Neighborhood Hits	98	Target Neighborhood Hits	1615	Shared Neighborhood Hits	45
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

KKCC1_MOUSE
θ value	1.06291 (rank : 17)	NC score	0.010345 (rank : 93)
Query Neighborhood Hits	98	Target Neighborhood Hits	866	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VBY2, Q9R054	Gene names	Camkk1, Camkk
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase kinase 1 (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinase kinase alpha) (CaM-KK alpha) (CaMKK alpha) (CaMKK 1) (CaM-kinase IV kinase).

RAI1_HUMAN
θ value	1.06291 (rank : 18)	NC score	0.049413 (rank : 7)
Query Neighborhood Hits	98	Target Neighborhood Hits	360	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

BAZ2A_MOUSE
θ value	1.38821 (rank : 19)	NC score	0.041270 (rank : 20)
Query Neighborhood Hits	98	Target Neighborhood Hits	744	Shared Neighborhood Hits	39
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

ICAL_MOUSE
θ value	1.38821 (rank : 20)	NC score	0.045568 (rank : 13)
Query Neighborhood Hits	98	Target Neighborhood Hits	178	Shared Neighborhood Hits	14
SwissProt Accessions	P51125, Q9EQV4, Q9EQV5, Q9QXQ3, Q9QXQ4, Q9R0N1	Gene names	Cast
Domain Architecture
Description	Calpastatin (Calpain inhibitor).

MEGF9_MOUSE
θ value	1.38821 (rank : 21)	NC score	0.024767 (rank : 47)
Query Neighborhood Hits	98	Target Neighborhood Hits	896	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

SRRM1_MOUSE
θ value	1.38821 (rank : 22)	NC score	0.047344 (rank : 10)
Query Neighborhood Hits	98	Target Neighborhood Hits	966	Shared Neighborhood Hits	39
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

T22D2_HUMAN
θ value	1.38821 (rank : 23)	NC score	0.041969 (rank : 18)
Query Neighborhood Hits	98	Target Neighborhood Hits	250	Shared Neighborhood Hits	17
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

CK024_MOUSE
θ value	1.81305 (rank : 24)	NC score	0.049117 (rank : 8)
Query Neighborhood Hits	98	Target Neighborhood Hits	307	Shared Neighborhood Hits	18
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

R113A_HUMAN
θ value	1.81305 (rank : 25)	NC score	0.036355 (rank : 25)
Query Neighborhood Hits	98	Target Neighborhood Hits	177	Shared Neighborhood Hits	5
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

SSH2_HUMAN
θ value	1.81305 (rank : 26)	NC score	0.019262 (rank : 59)
Query Neighborhood Hits	98	Target Neighborhood Hits	140	Shared Neighborhood Hits	4
SwissProt Accessions	Q76I76, Q8TDB5, Q8WYL1, Q8WYL2, Q96F40, Q96H36, Q9C0D8	Gene names	SSH2, KIAA1725, SSH2L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (hSSH-2L).

CBP_MOUSE
θ value	2.36792 (rank : 27)	NC score	0.051044 (rank : 6)
Query Neighborhood Hits	98	Target Neighborhood Hits	1051	Shared Neighborhood Hits	44
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

MN1_HUMAN
θ value	2.36792 (rank : 28)	NC score	0.045897 (rank : 12)
Query Neighborhood Hits	98	Target Neighborhood Hits	196	Shared Neighborhood Hits	13
SwissProt Accessions	Q10571	Gene names	MN1
Domain Architecture	No domain graphic available
Description	Probable tumor suppressor protein MN1.

SREC2_HUMAN
θ value	2.36792 (rank : 29)	NC score	0.013893 (rank : 80)
Query Neighborhood Hits	98	Target Neighborhood Hits	645	Shared Neighborhood Hits	17
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

TFE3_HUMAN
θ value	2.36792 (rank : 30)	NC score	0.030571 (rank : 35)
Query Neighborhood Hits	98	Target Neighborhood Hits	190	Shared Neighborhood Hits	8
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

TMAP1_HUMAN
θ value	2.36792 (rank : 31)	NC score	0.046513 (rank : 11)
Query Neighborhood Hits	98	Target Neighborhood Hits	140	Shared Neighborhood Hits	8
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

TRI47_MOUSE
θ value	2.36792 (rank : 32)	NC score	0.016902 (rank : 70)
Query Neighborhood Hits	98	Target Neighborhood Hits	295	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

COEA1_MOUSE
θ value	3.0926 (rank : 33)	NC score	0.016799 (rank : 72)
Query Neighborhood Hits	98	Target Neighborhood Hits	402	Shared Neighborhood Hits	14
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

CSKI1_MOUSE
θ value	3.0926 (rank : 34)	NC score	0.019058 (rank : 61)
Query Neighborhood Hits	98	Target Neighborhood Hits	1031	Shared Neighborhood Hits	36
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

ENAH_MOUSE
θ value	3.0926 (rank : 35)	NC score	0.030355 (rank : 36)
Query Neighborhood Hits	98	Target Neighborhood Hits	919	Shared Neighborhood Hits	35
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

LDB3_HUMAN
θ value	3.0926 (rank : 36)	NC score	0.019104 (rank : 60)
Query Neighborhood Hits	98	Target Neighborhood Hits	497	Shared Neighborhood Hits	19
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

MAP2_MOUSE
θ value	3.0926 (rank : 37)	NC score	0.029825 (rank : 37)
Query Neighborhood Hits	98	Target Neighborhood Hits	342	Shared Neighborhood Hits	13
SwissProt Accessions	P20357	Gene names	Map2, Mtap2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2).

MLL3_MOUSE
θ value	3.0926 (rank : 38)	NC score	0.044530 (rank : 16)
Query Neighborhood Hits	98	Target Neighborhood Hits	1399	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

NPHP4_HUMAN
θ value	3.0926 (rank : 39)	NC score	0.028234 (rank : 41)
Query Neighborhood Hits	98	Target Neighborhood Hits	60	Shared Neighborhood Hits	6
SwissProt Accessions	O75161	Gene names	NPHP4, KIAA0673
Domain Architecture	No domain graphic available
Description	Nephrocystin-4 (Nephroretinin).

PRRT3_HUMAN
θ value	3.0926 (rank : 40)	NC score	0.045245 (rank : 14)
Query Neighborhood Hits	98	Target Neighborhood Hits	998	Shared Neighborhood Hits	45
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

RAI1_MOUSE
θ value	3.0926 (rank : 41)	NC score	0.045114 (rank : 15)
Query Neighborhood Hits	98	Target Neighborhood Hits	344	Shared Neighborhood Hits	19
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RUNX1_HUMAN
θ value	3.0926 (rank : 42)	NC score	0.021525 (rank : 54)
Query Neighborhood Hits	98	Target Neighborhood Hits	94	Shared Neighborhood Hits	6
SwissProt Accessions	Q01196, O60472, O60473, O76047, O76089, Q13081, Q13755, Q13756, Q13757, Q13758, Q13759, Q15341, Q15343, Q16122, Q16284, Q16285, Q16286, Q16346, Q16347, Q92479	Gene names	RUNX1, AML1, CBFA2
Domain Architecture
Description	Runt-related transcription factor 1 (Core-binding factor, alpha 2 subunit) (CBF-alpha 2) (Acute myeloid leukemia 1 protein) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEBP2-alpha B) (PEA2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit).

SAM14_HUMAN
θ value	3.0926 (rank : 43)	NC score	0.029763 (rank : 38)
Query Neighborhood Hits	98	Target Neighborhood Hits	81	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IZD0, Q8N2X0	Gene names	SAMD14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

YLPM1_HUMAN
θ value	3.0926 (rank : 44)	NC score	0.038125 (rank : 24)
Query Neighborhood Hits	98	Target Neighborhood Hits	670	Shared Neighborhood Hits	35
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

ATBF1_MOUSE
θ value	4.03905 (rank : 45)	NC score	0.013648 (rank : 82)
Query Neighborhood Hits	98	Target Neighborhood Hits	1841	Shared Neighborhood Hits	27
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

BRD4_MOUSE
θ value	4.03905 (rank : 46)	NC score	0.032889 (rank : 31)
Query Neighborhood Hits	98	Target Neighborhood Hits	845	Shared Neighborhood Hits	26
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

CHD4_HUMAN
θ value	4.03905 (rank : 47)	NC score	0.025618 (rank : 45)
Query Neighborhood Hits	98	Target Neighborhood Hits	365	Shared Neighborhood Hits	8
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

DCJ14_MOUSE
θ value	4.03905 (rank : 48)	NC score	0.018464 (rank : 64)
Query Neighborhood Hits	98	Target Neighborhood Hits	99	Shared Neighborhood Hits	4
SwissProt Accessions	Q921R4, Q3TX73, Q8BUU3, Q9CYB7	Gene names	Dnajc14
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 14.

H15_HUMAN
θ value	4.03905 (rank : 49)	NC score	0.024256 (rank : 49)
Query Neighborhood Hits	98	Target Neighborhood Hits	76	Shared Neighborhood Hits	6
SwissProt Accessions	P16401, Q14529	Gene names	HIST1H1B, H1F5
Domain Architecture
Description	Histone H1.5 (Histone H1a).

IQEC3_HUMAN
θ value	4.03905 (rank : 50)	NC score	0.019384 (rank : 58)
Query Neighborhood Hits	98	Target Neighborhood Hits	125	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UPP2, Q8TB43	Gene names	IQSEC3, KIAA1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

MAML1_MOUSE
θ value	4.03905 (rank : 51)	NC score	0.027726 (rank : 43)
Query Neighborhood Hits	98	Target Neighborhood Hits	279	Shared Neighborhood Hits	20
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

PHC1_HUMAN
θ value	4.03905 (rank : 52)	NC score	0.025545 (rank : 46)
Query Neighborhood Hits	98	Target Neighborhood Hits	227	Shared Neighborhood Hits	16
SwissProt Accessions	P78364, Q8WVM3, Q9BU63	Gene names	PHC1, EDR1, PH1
Domain Architecture
Description	Polyhomeotic-like protein 1 (hPH1) (Early development regulatory protein 1).

PTTG1_HUMAN
θ value	4.03905 (rank : 53)	NC score	0.033341 (rank : 30)
Query Neighborhood Hits	98	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	O95997	Gene names	PTTG1, EAP1, PTTG, TUTR1
Domain Architecture
Description	Securin (Pituitary tumor-transforming protein 1) (Tumor-transforming protein 1) (Esp1-associated protein) (hPTTG).

RRBP1_MOUSE
θ value	4.03905 (rank : 54)	NC score	0.010963 (rank : 89)
Query Neighborhood Hits	98	Target Neighborhood Hits	1650	Shared Neighborhood Hits	24
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

TAU_MOUSE
θ value	4.03905 (rank : 55)	NC score	0.040074 (rank : 23)
Query Neighborhood Hits	98	Target Neighborhood Hits	502	Shared Neighborhood Hits	28
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TTBK1_HUMAN
θ value	4.03905 (rank : 56)	NC score	0.010530 (rank : 91)
Query Neighborhood Hits	98	Target Neighborhood Hits	1058	Shared Neighborhood Hits	21
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

ATF7_HUMAN
θ value	5.27518 (rank : 57)	NC score	0.014377 (rank : 79)
Query Neighborhood Hits	98	Target Neighborhood Hits	333	Shared Neighborhood Hits	3
SwissProt Accessions	P17544, Q13814	Gene names	ATF7, ATFA
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

BRD4_HUMAN
θ value	5.27518 (rank : 58)	NC score	0.031625 (rank : 33)
Query Neighborhood Hits	98	Target Neighborhood Hits	851	Shared Neighborhood Hits	28
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

BSN_HUMAN
θ value	5.27518 (rank : 59)	NC score	0.033341 (rank : 29)
Query Neighborhood Hits	98	Target Neighborhood Hits	1537	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CXA7_HUMAN
θ value	5.27518 (rank : 60)	NC score	0.013275 (rank : 84)
Query Neighborhood Hits	98	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	P36383	Gene names	GJA7
Domain Architecture
Description	Gap junction alpha-7 protein (Connexin-45) (Cx45).

CXA7_MOUSE
θ value	5.27518 (rank : 61)	NC score	0.013361 (rank : 83)
Query Neighborhood Hits	98	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	P28229	Gene names	Gja7, Cxn-45
Domain Architecture
Description	Gap junction alpha-7 protein (Connexin-45) (Cx45).

HCN2_MOUSE
θ value	5.27518 (rank : 62)	NC score	0.012388 (rank : 86)
Query Neighborhood Hits	98	Target Neighborhood Hits	278	Shared Neighborhood Hits	17
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

IF3A_HUMAN
θ value	5.27518 (rank : 63)	NC score	0.010242 (rank : 94)
Query Neighborhood Hits	98	Target Neighborhood Hits	875	Shared Neighborhood Hits	10
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

K1802_MOUSE
θ value	5.27518 (rank : 64)	NC score	0.030827 (rank : 34)
Query Neighborhood Hits	98	Target Neighborhood Hits	1596	Shared Neighborhood Hits	50
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

ODO2_HUMAN
θ value	5.27518 (rank : 65)	NC score	0.023999 (rank : 50)
Query Neighborhood Hits	98	Target Neighborhood Hits	58	Shared Neighborhood Hits	8
SwissProt Accessions	P36957, Q9BQ32	Gene names	DLST, DLTS
Domain Architecture
Description	Dihydrolipoyllysine-residue succinyltransferase component of 2- oxoglutarate dehydrogenase complex, mitochondrial precursor (EC 2.3.1.61) (Dihydrolipoamide succinyltransferase component of 2- oxoglutarate dehydrogenase complex) (E2) (E2K).

RIF1_HUMAN
θ value	5.27518 (rank : 66)	NC score	0.018320 (rank : 66)
Query Neighborhood Hits	98	Target Neighborhood Hits	320	Shared Neighborhood Hits	7
SwissProt Accessions	Q5UIP0, Q5H9R3, Q5UIP2, Q66YK6, Q6PRU2, Q8TE94, Q99772, Q9H830, Q9H9B9, Q9NVP5, Q9Y4R4	Gene names	RIF1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog).

SPEG_MOUSE
θ value	5.27518 (rank : 67)	NC score	0.016578 (rank : 73)
Query Neighborhood Hits	98	Target Neighborhood Hits	1959	Shared Neighborhood Hits	52
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TSSK2_HUMAN
θ value	5.27518 (rank : 68)	NC score	0.005156 (rank : 96)
Query Neighborhood Hits	98	Target Neighborhood Hits	826	Shared Neighborhood Hits	9
SwissProt Accessions	Q96PF2, Q8IY55	Gene names	TSSK2, DGSG, SPOGA2, STK22B
Domain Architecture
Description	Testis-specific serine/threonine-protein kinase 2 (EC 2.7.11.1) (TSSK- 2) (Testis-specific kinase 2) (TSK-2) (Serine/threonine-protein kinase 22B) (DiGeorge syndrome protein G).

WASIP_MOUSE
θ value	5.27518 (rank : 69)	NC score	0.043434 (rank : 17)
Query Neighborhood Hits	98	Target Neighborhood Hits	392	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

AFF1_MOUSE
θ value	6.88961 (rank : 70)	NC score	0.018182 (rank : 68)
Query Neighborhood Hits	98	Target Neighborhood Hits	351	Shared Neighborhood Hits	14
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

COEA1_HUMAN
θ value	6.88961 (rank : 71)	NC score	0.015277 (rank : 76)
Query Neighborhood Hits	98	Target Neighborhood Hits	427	Shared Neighborhood Hits	13
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

G7D_HUMAN
θ value	6.88961 (rank : 72)	NC score	0.026467 (rank : 44)
Query Neighborhood Hits	98	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q5SSQ6, Q9Y335	Gene names	C6orf26, G7D, NG23
Domain Architecture	No domain graphic available
Description	Protein G7d.

IRX1_HUMAN
θ value	6.88961 (rank : 73)	NC score	0.010444 (rank : 92)
Query Neighborhood Hits	98	Target Neighborhood Hits	285	Shared Neighborhood Hits	5
SwissProt Accessions	P78414, Q7Z2F8, Q8N312	Gene names	IRX1, IRXA1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-1 (Iroquois homeobox protein 1) (Homeodomain protein IRXA1).

KBTBB_HUMAN
θ value	6.88961 (rank : 74)	NC score	0.010574 (rank : 90)
Query Neighborhood Hits	98	Target Neighborhood Hits	195	Shared Neighborhood Hits	6
SwissProt Accessions	O94819	Gene names	KBTBD11, KIAA0711, KLHDC7C
Domain Architecture	No domain graphic available
Description	Kelch repeat and BTB domain-containing protein 11 (Kelch domain- containing protein 7B).

KKCC1_HUMAN
θ value	6.88961 (rank : 75)	NC score	0.007179 (rank : 95)
Query Neighborhood Hits	98	Target Neighborhood Hits	858	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N5S9, Q9BQH3	Gene names	CAMKK1, CAMKKA
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase kinase 1 (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinase kinase alpha) (CaM-KK alpha) (CaMKK alpha) (CaMKK 1) (CaM-kinase IV kinase).

MARCS_HUMAN
θ value	6.88961 (rank : 76)	NC score	0.028828 (rank : 39)
Query Neighborhood Hits	98	Target Neighborhood Hits	204	Shared Neighborhood Hits	15
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

MDC1_MOUSE
θ value	6.88961 (rank : 77)	NC score	0.048959 (rank : 9)
Query Neighborhood Hits	98	Target Neighborhood Hits	998	Shared Neighborhood Hits	51
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

RIN3_HUMAN
θ value	6.88961 (rank : 78)	NC score	0.041493 (rank : 19)
Query Neighborhood Hits	98	Target Neighborhood Hits	227	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

RTEL1_HUMAN
θ value	6.88961 (rank : 79)	NC score	0.017480 (rank : 69)
Query Neighborhood Hits	98	Target Neighborhood Hits	116	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NZ71, Q5JTV4, Q9BW37, Q9H402, Q9H4X6, Q9NX25, Q9NZ73, Q9UPR4, Q9Y4R6	Gene names	RTEL1, C20orf41, KIAA1088, NHL
Domain Architecture
Description	Regulator of telomere elongation helicase 1 (EC 3.6.1.-) (Helicase- like protein NHL).

SPEG_HUMAN
θ value	6.88961 (rank : 80)	NC score	0.013141 (rank : 85)
Query Neighborhood Hits	98	Target Neighborhood Hits	1762	Shared Neighborhood Hits	36
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TFEB_MOUSE
θ value	6.88961 (rank : 81)	NC score	0.022017 (rank : 52)
Query Neighborhood Hits	98	Target Neighborhood Hits	119	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

WASIP_HUMAN
θ value	6.88961 (rank : 82)	NC score	0.040196 (rank : 22)
Query Neighborhood Hits	98	Target Neighborhood Hits	458	Shared Neighborhood Hits	24
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

ZIMP7_HUMAN
θ value	6.88961 (rank : 83)	NC score	0.014669 (rank : 77)
Query Neighborhood Hits	98	Target Neighborhood Hits	290	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NF64, O94790, Q659A8, Q6JKL5, Q8WTX8, Q96Q01, Q9BQH7	Gene names	ZIMP7, KIAA1886
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ADA2B_MOUSE
θ value	8.99809 (rank : 84)	NC score	0.000024 (rank : 98)
Query Neighborhood Hits	98	Target Neighborhood Hits	891	Shared Neighborhood Hits	2
SwissProt Accessions	P30545	Gene names	Adra2b
Domain Architecture
Description	Alpha-2B adrenergic receptor (Alpha-2B adrenoceptor) (Alpha-2B adrenoreceptor).

ATBF1_HUMAN
θ value	8.99809 (rank : 85)	NC score	0.013845 (rank : 81)
Query Neighborhood Hits	98	Target Neighborhood Hits	1547	Shared Neighborhood Hits	29
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

EPN3_HUMAN
θ value	8.99809 (rank : 86)	NC score	0.015756 (rank : 75)
Query Neighborhood Hits	98	Target Neighborhood Hits	197	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H201, Q9BVN6, Q9NWK2	Gene names	EPN3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

FOXC2_MOUSE
θ value	8.99809 (rank : 87)	NC score	0.004746 (rank : 97)
Query Neighborhood Hits	98	Target Neighborhood Hits	124	Shared Neighborhood Hits	4
SwissProt Accessions	Q61850, P97948, Q63869, Q8C694	Gene names	Foxc2, Fkh14, Fkhl14, Mfh1
Domain Architecture
Description	Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14).

H14_HUMAN
θ value	8.99809 (rank : 88)	NC score	0.019388 (rank : 57)
Query Neighborhood Hits	98	Target Neighborhood Hits	87	Shared Neighborhood Hits	8
SwissProt Accessions	P10412	Gene names	HIST1H1E, H1F4
Domain Architecture
Description	Histone H1.4 (Histone H1b).

H15_MOUSE
θ value	8.99809 (rank : 89)	NC score	0.018657 (rank : 63)
Query Neighborhood Hits	98	Target Neighborhood Hits	79	Shared Neighborhood Hits	6
SwissProt Accessions	P43276, Q9CRM8	Gene names	Hist1h1b, H1f5
Domain Architecture
Description	Histone H1.5 (H1 VAR.5) (H1b).

IASPP_MOUSE
θ value	8.99809 (rank : 90)	NC score	0.018334 (rank : 65)
Query Neighborhood Hits	98	Target Neighborhood Hits	1024	Shared Neighborhood Hits	35
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

MAP1A_HUMAN
θ value	8.99809 (rank : 91)	NC score	0.019942 (rank : 56)
Query Neighborhood Hits	98	Target Neighborhood Hits	1626	Shared Neighborhood Hits	49
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MGAT1_MOUSE
θ value	8.99809 (rank : 92)	NC score	0.014647 (rank : 78)
Query Neighborhood Hits	98	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	P27808	Gene names	Mgat1, Gnt1
Domain Architecture
Description	Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (EC 2.4.1.101) (N-glycosyl-oligosaccharide-glycoprotein N- acetylglucosaminyltransferase I) (GNT-I) (GlcNAc-T I).

ODP2_HUMAN
θ value	8.99809 (rank : 93)	NC score	0.018313 (rank : 67)
Query Neighborhood Hits	98	Target Neighborhood Hits	59	Shared Neighborhood Hits	5
SwissProt Accessions	P10515, Q16783	Gene names	DLAT, DLTA
Domain Architecture
Description	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial precursor (EC 2.3.1.12) (Pyruvate dehydrogenase complex E2 subunit) (PDCE2) (E2) (Dihydrolipoamide S- acetyltransferase component of pyruvate dehydrogenase complex) (PDC- E2) (70 kDa mitochondrial autoantigen of primary biliary cirrhosis) (PBC) (M2 antigen complex 70 kDa subunit).

PCLO_HUMAN
θ value	8.99809 (rank : 94)	NC score	0.031717 (rank : 32)
Query Neighborhood Hits	98	Target Neighborhood Hits	2046	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

S23IP_MOUSE
θ value	8.99809 (rank : 95)	NC score	0.018692 (rank : 62)
Query Neighborhood Hits	98	Target Neighborhood Hits	363	Shared Neighborhood Hits	21
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

TAF3_HUMAN
θ value	8.99809 (rank : 96)	NC score	0.020864 (rank : 55)
Query Neighborhood Hits	98	Target Neighborhood Hits	568	Shared Neighborhood Hits	20
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TOP2A_MOUSE
θ value	8.99809 (rank : 97)	NC score	0.011297 (rank : 87)
Query Neighborhood Hits	98	Target Neighborhood Hits	101	Shared Neighborhood Hits	5
SwissProt Accessions	Q01320	Gene names	Top2a, Top-2, Top2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

ZN318_MOUSE
θ value	8.99809 (rank : 98)	NC score	0.016872 (rank : 71)
Query Neighborhood Hits	98	Target Neighborhood Hits	642	Shared Neighborhood Hits	24
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

Hits sorted by NC score

CS021_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	98	Target Neighborhood Hits	98	Shared Neighborhood Hits	98
SwissProt Accessions	Q8IVT2	Gene names	C19orf21
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf21.

CS021_MOUSE
NC score	0.948204 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	98	Target Neighborhood Hits	47	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D279, Q3UI04	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf21 homolog.

AKAP2_HUMAN
NC score	0.171412 (rank : 3)	θ value	0.00035302 (rank : 3)
Query Neighborhood Hits	98	Target Neighborhood Hits	507	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

AKAP2_MOUSE
NC score	0.130171 (rank : 4)	θ value	0.0252991 (rank : 5)
Query Neighborhood Hits	98	Target Neighborhood Hits	385	Shared Neighborhood Hits	14
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

CBP_HUMAN
NC score	0.058997 (rank : 5)	θ value	0.365318 (rank : 8)
Query Neighborhood Hits	98	Target Neighborhood Hits	941	Shared Neighborhood Hits	41
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CBP_MOUSE
NC score	0.051044 (rank : 6)	θ value	2.36792 (rank : 27)
Query Neighborhood Hits	98	Target Neighborhood Hits	1051	Shared Neighborhood Hits	44
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

RAI1_HUMAN
NC score	0.049413 (rank : 7)	θ value	1.06291 (rank : 18)
Query Neighborhood Hits	98	Target Neighborhood Hits	360	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

CK024_MOUSE
NC score	0.049117 (rank : 8)	θ value	1.81305 (rank : 24)
Query Neighborhood Hits	98	Target Neighborhood Hits	307	Shared Neighborhood Hits	18
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

MDC1_MOUSE
NC score	0.048959 (rank : 9)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	98	Target Neighborhood Hits	998	Shared Neighborhood Hits	51
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

SRRM1_MOUSE
NC score	0.047344 (rank : 10)	θ value	1.38821 (rank : 22)
Query Neighborhood Hits	98	Target Neighborhood Hits	966	Shared Neighborhood Hits	39
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TMAP1_HUMAN
NC score	0.046513 (rank : 11)	θ value	2.36792 (rank : 31)
Query Neighborhood Hits	98	Target Neighborhood Hits	140	Shared Neighborhood Hits	8
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

MN1_HUMAN
NC score	0.045897 (rank : 12)	θ value	2.36792 (rank : 28)
Query Neighborhood Hits	98	Target Neighborhood Hits	196	Shared Neighborhood Hits	13
SwissProt Accessions	Q10571	Gene names	MN1
Domain Architecture	No domain graphic available
Description	Probable tumor suppressor protein MN1.

ICAL_MOUSE
NC score	0.045568 (rank : 13)	θ value	1.38821 (rank : 20)
Query Neighborhood Hits	98	Target Neighborhood Hits	178	Shared Neighborhood Hits	14
SwissProt Accessions	P51125, Q9EQV4, Q9EQV5, Q9QXQ3, Q9QXQ4, Q9R0N1	Gene names	Cast
Domain Architecture
Description	Calpastatin (Calpain inhibitor).

PRRT3_HUMAN
NC score	0.045245 (rank : 14)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	98	Target Neighborhood Hits	998	Shared Neighborhood Hits	45
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

RAI1_MOUSE
NC score	0.045114 (rank : 15)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	98	Target Neighborhood Hits	344	Shared Neighborhood Hits	19
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

MLL3_MOUSE
NC score	0.044530 (rank : 16)	θ value	3.0926 (rank : 38)
Query Neighborhood Hits	98	Target Neighborhood Hits	1399	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

WASIP_MOUSE
NC score	0.043434 (rank : 17)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	98	Target Neighborhood Hits	392	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

T22D2_HUMAN
NC score	0.041969 (rank : 18)	θ value	1.38821 (rank : 23)
Query Neighborhood Hits	98	Target Neighborhood Hits	250	Shared Neighborhood Hits	17
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

RIN3_HUMAN
NC score	0.041493 (rank : 19)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	98	Target Neighborhood Hits	227	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

BAZ2A_MOUSE
NC score	0.041270 (rank : 20)	θ value	1.38821 (rank : 19)
Query Neighborhood Hits	98	Target Neighborhood Hits	744	Shared Neighborhood Hits	39
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

PRG4_HUMAN
NC score	0.040646 (rank : 21)	θ value	0.62314 (rank : 12)
Query Neighborhood Hits	98	Target Neighborhood Hits	764	Shared Neighborhood Hits	30
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

WASIP_HUMAN
NC score	0.040196 (rank : 22)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	98	Target Neighborhood Hits	458	Shared Neighborhood Hits	24
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

TAU_MOUSE
NC score	0.040074 (rank : 23)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	98	Target Neighborhood Hits	502	Shared Neighborhood Hits	28
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

YLPM1_HUMAN
NC score	0.038125 (rank : 24)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	98	Target Neighborhood Hits	670	Shared Neighborhood Hits	35
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

R113A_HUMAN
NC score	0.036355 (rank : 25)	θ value	1.81305 (rank : 25)
Query Neighborhood Hits	98	Target Neighborhood Hits	177	Shared Neighborhood Hits	5
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

MYO15_MOUSE
NC score	0.035260 (rank : 26)	θ value	0.00665767 (rank : 4)
Query Neighborhood Hits	98	Target Neighborhood Hits	467	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

CHD4_MOUSE
NC score	0.034983 (rank : 27)	θ value	0.0431538 (rank : 7)
Query Neighborhood Hits	98	Target Neighborhood Hits	408	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

DIP2A_HUMAN
NC score	0.034624 (rank : 28)	θ value	0.813845 (rank : 14)
Query Neighborhood Hits	98	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	Q14689, Q8IVA3, Q8N4S2, Q8TD89, Q96ML9	Gene names	DIP2A, C21orf106, DIP2, KIAA0184
Domain Architecture
Description	Disco-interacting protein 2 homolog A.

BSN_HUMAN
NC score	0.033341 (rank : 29)	θ value	5.27518 (rank : 59)
Query Neighborhood Hits	98	Target Neighborhood Hits	1537	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

PTTG1_HUMAN
NC score	0.033341 (rank : 30)	θ value	4.03905 (rank : 53)
Query Neighborhood Hits	98	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	O95997	Gene names	PTTG1, EAP1, PTTG, TUTR1
Domain Architecture
Description	Securin (Pituitary tumor-transforming protein 1) (Tumor-transforming protein 1) (Esp1-associated protein) (hPTTG).

BRD4_MOUSE
NC score	0.032889 (rank : 31)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	98	Target Neighborhood Hits	845	Shared Neighborhood Hits	26
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

PCLO_HUMAN
NC score	0.031717 (rank : 32)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	98	Target Neighborhood Hits	2046	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

BRD4_HUMAN
NC score	0.031625 (rank : 33)	θ value	5.27518 (rank : 58)
Query Neighborhood Hits	98	Target Neighborhood Hits	851	Shared Neighborhood Hits	28
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

K1802_MOUSE
NC score	0.030827 (rank : 34)	θ value	5.27518 (rank : 64)
Query Neighborhood Hits	98	Target Neighborhood Hits	1596	Shared Neighborhood Hits	50
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

TFE3_HUMAN
NC score	0.030571 (rank : 35)	θ value	2.36792 (rank : 30)
Query Neighborhood Hits	98	Target Neighborhood Hits	190	Shared Neighborhood Hits	8
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

ENAH_MOUSE
NC score	0.030355 (rank : 36)	θ value	3.0926 (rank : 35)
Query Neighborhood Hits	98	Target Neighborhood Hits	919	Shared Neighborhood Hits	35
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

MAP2_MOUSE
NC score	0.029825 (rank : 37)	θ value	3.0926 (rank : 37)
Query Neighborhood Hits	98	Target Neighborhood Hits	342	Shared Neighborhood Hits	13
SwissProt Accessions	P20357	Gene names	Map2, Mtap2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2).

SAM14_HUMAN
NC score	0.029763 (rank : 38)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	98	Target Neighborhood Hits	81	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IZD0, Q8N2X0	Gene names	SAMD14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

MARCS_HUMAN
NC score	0.028828 (rank : 39)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	98	Target Neighborhood Hits	204	Shared Neighborhood Hits	15
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

LIMD1_HUMAN
NC score	0.028332 (rank : 40)	θ value	0.47712 (rank : 9)
Query Neighborhood Hits	98	Target Neighborhood Hits	201	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UGP4, Q9BQQ9, Q9NQ47	Gene names	LIMD1
Domain Architecture
Description	LIM domain-containing protein 1.

NPHP4_HUMAN
NC score	0.028234 (rank : 41)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	98	Target Neighborhood Hits	60	Shared Neighborhood Hits	6
SwissProt Accessions	O75161	Gene names	NPHP4, KIAA0673
Domain Architecture	No domain graphic available
Description	Nephrocystin-4 (Nephroretinin).

AN13D_HUMAN
NC score	0.027828 (rank : 42)	θ value	1.06291 (rank : 15)
Query Neighborhood Hits	98	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZTN6, Q6ZVD0, Q86SU1	Gene names	ANKRD13D
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13D.

MAML1_MOUSE
NC score	0.027726 (rank : 43)	θ value	4.03905 (rank : 51)
Query Neighborhood Hits	98	Target Neighborhood Hits	279	Shared Neighborhood Hits	20
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

G7D_HUMAN
NC score	0.026467 (rank : 44)	θ value	6.88961 (rank : 72)
Query Neighborhood Hits	98	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q5SSQ6, Q9Y335	Gene names	C6orf26, G7D, NG23
Domain Architecture	No domain graphic available
Description	Protein G7d.

CHD4_HUMAN
NC score	0.025618 (rank : 45)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	98	Target Neighborhood Hits	365	Shared Neighborhood Hits	8
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

PHC1_HUMAN
NC score	0.025545 (rank : 46)	θ value	4.03905 (rank : 52)
Query Neighborhood Hits	98	Target Neighborhood Hits	227	Shared Neighborhood Hits	16
SwissProt Accessions	P78364, Q8WVM3, Q9BU63	Gene names	PHC1, EDR1, PH1
Domain Architecture
Description	Polyhomeotic-like protein 1 (hPH1) (Early development regulatory protein 1).

MEGF9_MOUSE
NC score	0.024767 (rank : 47)	θ value	1.38821 (rank : 21)
Query Neighborhood Hits	98	Target Neighborhood Hits	896	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

ROBO3_HUMAN
NC score	0.024732 (rank : 48)	θ value	0.0252991 (rank : 6)
Query Neighborhood Hits	98	Target Neighborhood Hits	570	Shared Neighborhood Hits	12
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

H15_HUMAN
NC score	0.024256 (rank : 49)	θ value	4.03905 (rank : 49)
Query Neighborhood Hits	98	Target Neighborhood Hits	76	Shared Neighborhood Hits	6
SwissProt Accessions	P16401, Q14529	Gene names	HIST1H1B, H1F5
Domain Architecture
Description	Histone H1.5 (Histone H1a).

ODO2_HUMAN
NC score	0.023999 (rank : 50)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	98	Target Neighborhood Hits	58	Shared Neighborhood Hits	8
SwissProt Accessions	P36957, Q9BQ32	Gene names	DLST, DLTS
Domain Architecture
Description	Dihydrolipoyllysine-residue succinyltransferase component of 2- oxoglutarate dehydrogenase complex, mitochondrial precursor (EC 2.3.1.61) (Dihydrolipoamide succinyltransferase component of 2- oxoglutarate dehydrogenase complex) (E2) (E2K).

MAGI2_HUMAN
NC score	0.023918 (rank : 51)	θ value	0.62314 (rank : 11)
Query Neighborhood Hits	98	Target Neighborhood Hits	373	Shared Neighborhood Hits	9
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

TFEB_MOUSE
NC score	0.022017 (rank : 52)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	98	Target Neighborhood Hits	119	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

ANK2_HUMAN
NC score	0.021965 (rank : 53)	θ value	1.06291 (rank : 16)
Query Neighborhood Hits	98	Target Neighborhood Hits	1615	Shared Neighborhood Hits	45
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

RUNX1_HUMAN
NC score	0.021525 (rank : 54)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	98	Target Neighborhood Hits	94	Shared Neighborhood Hits	6
SwissProt Accessions	Q01196, O60472, O60473, O76047, O76089, Q13081, Q13755, Q13756, Q13757, Q13758, Q13759, Q15341, Q15343, Q16122, Q16284, Q16285, Q16286, Q16346, Q16347, Q92479	Gene names	RUNX1, AML1, CBFA2
Domain Architecture
Description	Runt-related transcription factor 1 (Core-binding factor, alpha 2 subunit) (CBF-alpha 2) (Acute myeloid leukemia 1 protein) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEBP2-alpha B) (PEA2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit).

TAF3_HUMAN
NC score	0.020864 (rank : 55)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	98	Target Neighborhood Hits	568	Shared Neighborhood Hits	20
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

MAP1A_HUMAN
NC score	0.019942 (rank : 56)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	98	Target Neighborhood Hits	1626	Shared Neighborhood Hits	49
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

H14_HUMAN
NC score	0.019388 (rank : 57)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	98	Target Neighborhood Hits	87	Shared Neighborhood Hits	8
SwissProt Accessions	P10412	Gene names	HIST1H1E, H1F4
Domain Architecture
Description	Histone H1.4 (Histone H1b).

IQEC3_HUMAN
NC score	0.019384 (rank : 58)	θ value	4.03905 (rank : 50)
Query Neighborhood Hits	98	Target Neighborhood Hits	125	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UPP2, Q8TB43	Gene names	IQSEC3, KIAA1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

SSH2_HUMAN
NC score	0.019262 (rank : 59)	θ value	1.81305 (rank : 26)
Query Neighborhood Hits	98	Target Neighborhood Hits	140	Shared Neighborhood Hits	4
SwissProt Accessions	Q76I76, Q8TDB5, Q8WYL1, Q8WYL2, Q96F40, Q96H36, Q9C0D8	Gene names	SSH2, KIAA1725, SSH2L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (hSSH-2L).

LDB3_HUMAN
NC score	0.019104 (rank : 60)	θ value	3.0926 (rank : 36)
Query Neighborhood Hits	98	Target Neighborhood Hits	497	Shared Neighborhood Hits	19
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

CSKI1_MOUSE
NC score	0.019058 (rank : 61)	θ value	3.0926 (rank : 34)
Query Neighborhood Hits	98	Target Neighborhood Hits	1031	Shared Neighborhood Hits	36
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

S23IP_MOUSE
NC score	0.018692 (rank : 62)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	98	Target Neighborhood Hits	363	Shared Neighborhood Hits	21
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

H15_MOUSE
NC score	0.018657 (rank : 63)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	98	Target Neighborhood Hits	79	Shared Neighborhood Hits	6
SwissProt Accessions	P43276, Q9CRM8	Gene names	Hist1h1b, H1f5
Domain Architecture
Description	Histone H1.5 (H1 VAR.5) (H1b).

DCJ14_MOUSE
NC score	0.018464 (rank : 64)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	98	Target Neighborhood Hits	99	Shared Neighborhood Hits	4
SwissProt Accessions	Q921R4, Q3TX73, Q8BUU3, Q9CYB7	Gene names	Dnajc14
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 14.

IASPP_MOUSE
NC score	0.018334 (rank : 65)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	98	Target Neighborhood Hits	1024	Shared Neighborhood Hits	35
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

RIF1_HUMAN
NC score	0.018320 (rank : 66)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	98	Target Neighborhood Hits	320	Shared Neighborhood Hits	7
SwissProt Accessions	Q5UIP0, Q5H9R3, Q5UIP2, Q66YK6, Q6PRU2, Q8TE94, Q99772, Q9H830, Q9H9B9, Q9NVP5, Q9Y4R4	Gene names	RIF1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog).

ODP2_HUMAN
NC score	0.018313 (rank : 67)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	98	Target Neighborhood Hits	59	Shared Neighborhood Hits	5
SwissProt Accessions	P10515, Q16783	Gene names	DLAT, DLTA
Domain Architecture
Description	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial precursor (EC 2.3.1.12) (Pyruvate dehydrogenase complex E2 subunit) (PDCE2) (E2) (Dihydrolipoamide S- acetyltransferase component of pyruvate dehydrogenase complex) (PDC- E2) (70 kDa mitochondrial autoantigen of primary biliary cirrhosis) (PBC) (M2 antigen complex 70 kDa subunit).

AFF1_MOUSE
NC score	0.018182 (rank : 68)	θ value	6.88961 (rank : 70)
Query Neighborhood Hits	98	Target Neighborhood Hits	351	Shared Neighborhood Hits	14
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

RTEL1_HUMAN
NC score	0.017480 (rank : 69)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	98	Target Neighborhood Hits	116	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NZ71, Q5JTV4, Q9BW37, Q9H402, Q9H4X6, Q9NX25, Q9NZ73, Q9UPR4, Q9Y4R6	Gene names	RTEL1, C20orf41, KIAA1088, NHL
Domain Architecture
Description	Regulator of telomere elongation helicase 1 (EC 3.6.1.-) (Helicase- like protein NHL).

TRI47_MOUSE
NC score	0.016902 (rank : 70)	θ value	2.36792 (rank : 32)
Query Neighborhood Hits	98	Target Neighborhood Hits	295	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

ZN318_MOUSE
NC score	0.016872 (rank : 71)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	98	Target Neighborhood Hits	642	Shared Neighborhood Hits	24
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

COEA1_MOUSE
NC score	0.016799 (rank : 72)	θ value	3.0926 (rank : 33)
Query Neighborhood Hits	98	Target Neighborhood Hits	402	Shared Neighborhood Hits	14
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

SPEG_MOUSE
NC score	0.016578 (rank : 73)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	98	Target Neighborhood Hits	1959	Shared Neighborhood Hits	52
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

WNK2_HUMAN
NC score	0.016136 (rank : 74)	θ value	0.62314 (rank : 13)
Query Neighborhood Hits	98	Target Neighborhood Hits	1407	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

EPN3_HUMAN
NC score	0.015756 (rank : 75)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	98	Target Neighborhood Hits	197	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H201, Q9BVN6, Q9NWK2	Gene names	EPN3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

COEA1_HUMAN
NC score	0.015277 (rank : 76)	θ value	6.88961 (rank : 71)
Query Neighborhood Hits	98	Target Neighborhood Hits	427	Shared Neighborhood Hits	13
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

ZIMP7_HUMAN
NC score	0.014669 (rank : 77)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	98	Target Neighborhood Hits	290	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NF64, O94790, Q659A8, Q6JKL5, Q8WTX8, Q96Q01, Q9BQH7	Gene names	ZIMP7, KIAA1886
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

MGAT1_MOUSE
NC score	0.014647 (rank : 78)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	98	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	P27808	Gene names	Mgat1, Gnt1
Domain Architecture
Description	Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (EC 2.4.1.101) (N-glycosyl-oligosaccharide-glycoprotein N- acetylglucosaminyltransferase I) (GNT-I) (GlcNAc-T I).

ATF7_HUMAN
NC score	0.014377 (rank : 79)	θ value	5.27518 (rank : 57)
Query Neighborhood Hits	98	Target Neighborhood Hits	333	Shared Neighborhood Hits	3
SwissProt Accessions	P17544, Q13814	Gene names	ATF7, ATFA
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

SREC2_HUMAN
NC score	0.013893 (rank : 80)	θ value	2.36792 (rank : 29)
Query Neighborhood Hits	98	Target Neighborhood Hits	645	Shared Neighborhood Hits	17
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

ATBF1_HUMAN
NC score	0.013845 (rank : 81)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	98	Target Neighborhood Hits	1547	Shared Neighborhood Hits	29
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

ATBF1_MOUSE
NC score	0.013648 (rank : 82)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	98	Target Neighborhood Hits	1841	Shared Neighborhood Hits	27
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

CXA7_MOUSE
NC score	0.013361 (rank : 83)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	98	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	P28229	Gene names	Gja7, Cxn-45
Domain Architecture
Description	Gap junction alpha-7 protein (Connexin-45) (Cx45).

CXA7_HUMAN
NC score	0.013275 (rank : 84)	θ value	5.27518 (rank : 60)
Query Neighborhood Hits	98	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	P36383	Gene names	GJA7
Domain Architecture
Description	Gap junction alpha-7 protein (Connexin-45) (Cx45).

SPEG_HUMAN
NC score	0.013141 (rank : 85)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	98	Target Neighborhood Hits	1762	Shared Neighborhood Hits	36
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

HCN2_MOUSE
NC score	0.012388 (rank : 86)	θ value	5.27518 (rank : 62)
Query Neighborhood Hits	98	Target Neighborhood Hits	278	Shared Neighborhood Hits	17
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

TOP2A_MOUSE
NC score	0.011297 (rank : 87)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	98	Target Neighborhood Hits	101	Shared Neighborhood Hits	5
SwissProt Accessions	Q01320	Gene names	Top2a, Top-2, Top2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

ACK1_MOUSE
NC score	0.011117 (rank : 88)	θ value	0.62314 (rank : 10)
Query Neighborhood Hits	98	Target Neighborhood Hits	1080	Shared Neighborhood Hits	28
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

RRBP1_MOUSE
NC score	0.010963 (rank : 89)	θ value	4.03905 (rank : 54)
Query Neighborhood Hits	98	Target Neighborhood Hits	1650	Shared Neighborhood Hits	24
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

KBTBB_HUMAN
NC score	0.010574 (rank : 90)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	98	Target Neighborhood Hits	195	Shared Neighborhood Hits	6
SwissProt Accessions	O94819	Gene names	KBTBD11, KIAA0711, KLHDC7C
Domain Architecture	No domain graphic available
Description	Kelch repeat and BTB domain-containing protein 11 (Kelch domain- containing protein 7B).

TTBK1_HUMAN
NC score	0.010530 (rank : 91)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	98	Target Neighborhood Hits	1058	Shared Neighborhood Hits	21
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

IRX1_HUMAN
NC score	0.010444 (rank : 92)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	98	Target Neighborhood Hits	285	Shared Neighborhood Hits	5
SwissProt Accessions	P78414, Q7Z2F8, Q8N312	Gene names	IRX1, IRXA1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-1 (Iroquois homeobox protein 1) (Homeodomain protein IRXA1).

KKCC1_MOUSE
NC score	0.010345 (rank : 93)	θ value	1.06291 (rank : 17)
Query Neighborhood Hits	98	Target Neighborhood Hits	866	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VBY2, Q9R054	Gene names	Camkk1, Camkk
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase kinase 1 (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinase kinase alpha) (CaM-KK alpha) (CaMKK alpha) (CaMKK 1) (CaM-kinase IV kinase).

IF3A_HUMAN
NC score	0.010242 (rank : 94)	θ value	5.27518 (rank : 63)
Query Neighborhood Hits	98	Target Neighborhood Hits	875	Shared Neighborhood Hits	10
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

KKCC1_HUMAN
NC score	0.007179 (rank : 95)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	98	Target Neighborhood Hits	858	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N5S9, Q9BQH3	Gene names	CAMKK1, CAMKKA
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase kinase 1 (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinase kinase alpha) (CaM-KK alpha) (CaMKK alpha) (CaMKK 1) (CaM-kinase IV kinase).

TSSK2_HUMAN
NC score	0.005156 (rank : 96)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	98	Target Neighborhood Hits	826	Shared Neighborhood Hits	9
SwissProt Accessions	Q96PF2, Q8IY55	Gene names	TSSK2, DGSG, SPOGA2, STK22B
Domain Architecture
Description	Testis-specific serine/threonine-protein kinase 2 (EC 2.7.11.1) (TSSK- 2) (Testis-specific kinase 2) (TSK-2) (Serine/threonine-protein kinase 22B) (DiGeorge syndrome protein G).

FOXC2_MOUSE
NC score	0.004746 (rank : 97)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	98	Target Neighborhood Hits	124	Shared Neighborhood Hits	4
SwissProt Accessions	Q61850, P97948, Q63869, Q8C694	Gene names	Foxc2, Fkh14, Fkhl14, Mfh1
Domain Architecture
Description	Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14).

ADA2B_MOUSE
NC score	0.000024 (rank : 98)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	98	Target Neighborhood Hits	891	Shared Neighborhood Hits	2
SwissProt Accessions	P30545	Gene names	Adra2b
Domain Architecture
Description	Alpha-2B adrenergic receptor (Alpha-2B adrenoceptor) (Alpha-2B adrenoreceptor).