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Network neighborhood for query Sequence : ZW10_MOUSE

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ZW10_MOUSE
SwissProt Accessions	O54692, Q3TIA5, Q3ULW1, Q921H3	Gene names	Zw10
Domain Architecture	No domain graphic available
Description	Centromere/kinetochore protein zw10 homolog.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ZW10_HUMAN
θ value	0 (rank : 1)	NC score	0.955531 (rank : 2)
Query Neighborhood Hits	86	Target Neighborhood Hits	101	Shared Neighborhood Hits	43
SwissProt Accessions	O43264	Gene names	ZW10
Domain Architecture
Description	Centromere/kinetochore protein zw10 homolog.

ZW10_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	86	Target Neighborhood Hits	86	Shared Neighborhood Hits	86
SwissProt Accessions	O54692, Q3TIA5, Q3ULW1, Q921H3	Gene names	Zw10
Domain Architecture	No domain graphic available
Description	Centromere/kinetochore protein zw10 homolog.

EXOC4_HUMAN
θ value	0.00134147 (rank : 3)	NC score	0.153233 (rank : 4)
Query Neighborhood Hits	86	Target Neighborhood Hits	72	Shared Neighborhood Hits	13
SwissProt Accessions	Q96A65, Q9C0G4, Q9H9K0, Q9P102	Gene names	EXOC4, KIAA1699, SEC8, SEC8L1
Domain Architecture
Description	Exocyst complex component 4 (Exocyst complex component Sec8).

EXOC4_MOUSE
θ value	0.00134147 (rank : 4)	NC score	0.153410 (rank : 3)
Query Neighborhood Hits	86	Target Neighborhood Hits	86	Shared Neighborhood Hits	16
SwissProt Accessions	O35382	Gene names	Exoc4, Sec8, Sec8l1
Domain Architecture
Description	Exocyst complex component 4 (Exocyst complex component Sec8).

CENPF_HUMAN
θ value	0.0113563 (rank : 5)	NC score	0.083973 (rank : 6)
Query Neighborhood Hits	86	Target Neighborhood Hits	1932	Shared Neighborhood Hits	55
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

KS6A2_MOUSE
θ value	0.0193708 (rank : 6)	NC score	0.039323 (rank : 79)
Query Neighborhood Hits	86	Target Neighborhood Hits	858	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WUT3, Q9D2C0	Gene names	Rps6ka2, Rsk3
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1) (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase- activated protein kinase 1c) (MAPKAPK1C).

KS6A2_HUMAN
θ value	0.0961366 (rank : 7)	NC score	0.036970 (rank : 83)
Query Neighborhood Hits	86	Target Neighborhood Hits	857	Shared Neighborhood Hits	22
SwissProt Accessions	Q15349, Q15419, Q59GJ3, Q5TI68, Q96J38, Q9UJN5	Gene names	RPS6KA2, RSK3
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1) (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C).

WRN_MOUSE
θ value	0.0961366 (rank : 8)	NC score	0.056813 (rank : 34)
Query Neighborhood Hits	86	Target Neighborhood Hits	295	Shared Neighborhood Hits	12
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

CENPE_HUMAN
θ value	0.125558 (rank : 9)	NC score	0.067228 (rank : 11)
Query Neighborhood Hits	86	Target Neighborhood Hits	2060	Shared Neighborhood Hits	57
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

GOGA2_HUMAN
θ value	0.125558 (rank : 10)	NC score	0.066327 (rank : 12)
Query Neighborhood Hits	86	Target Neighborhood Hits	856	Shared Neighborhood Hits	39
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

MYH13_HUMAN
θ value	0.125558 (rank : 11)	NC score	0.063149 (rank : 19)
Query Neighborhood Hits	86	Target Neighborhood Hits	1504	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

GCC1_MOUSE
θ value	0.163984 (rank : 12)	NC score	0.090294 (rank : 5)
Query Neighborhood Hits	86	Target Neighborhood Hits	777	Shared Neighborhood Hits	42
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

MYO5A_MOUSE
θ value	0.163984 (rank : 13)	NC score	0.054520 (rank : 45)
Query Neighborhood Hits	86	Target Neighborhood Hits	1117	Shared Neighborhood Hits	43
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

RB6I2_HUMAN
θ value	0.163984 (rank : 14)	NC score	0.064624 (rank : 15)
Query Neighborhood Hits	86	Target Neighborhood Hits	1584	Shared Neighborhood Hits	50
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

STK31_HUMAN
θ value	0.163984 (rank : 15)	NC score	0.073555 (rank : 9)
Query Neighborhood Hits	86	Target Neighborhood Hits	570	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BXU1, Q9BXH8	Gene names	STK31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1) (Serine/threonine- protein kinase NYD-SPK).

CP250_HUMAN
θ value	0.21417 (rank : 16)	NC score	0.059585 (rank : 28)
Query Neighborhood Hits	86	Target Neighborhood Hits	1805	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

K0999_HUMAN
θ value	0.279714 (rank : 17)	NC score	0.028755 (rank : 96)
Query Neighborhood Hits	86	Target Neighborhood Hits	899	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y2K2, Q59FY2, Q5M9N1, Q6P3R6, Q8IYM8, Q9HA50	Gene names	KIAA0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).

MYH4_HUMAN
θ value	0.279714 (rank : 18)	NC score	0.067564 (rank : 10)
Query Neighborhood Hits	86	Target Neighborhood Hits	1377	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

TRI15_HUMAN
θ value	0.279714 (rank : 19)	NC score	0.029405 (rank : 93)
Query Neighborhood Hits	86	Target Neighborhood Hits	395	Shared Neighborhood Hits	21
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

KS6A6_HUMAN
θ value	0.365318 (rank : 20)	NC score	0.035877 (rank : 84)
Query Neighborhood Hits	86	Target Neighborhood Hits	853	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UK32, Q8WX28, Q9H4S6	Gene names	RPS6KA6, RSK4
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1) (S6K-alpha 6) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4).

MYH4_MOUSE
θ value	0.365318 (rank : 21)	NC score	0.064995 (rank : 14)
Query Neighborhood Hits	86	Target Neighborhood Hits	1476	Shared Neighborhood Hits	53
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

STK31_MOUSE
θ value	0.47712 (rank : 22)	NC score	0.075140 (rank : 7)
Query Neighborhood Hits	86	Target Neighborhood Hits	474	Shared Neighborhood Hits	30
SwissProt Accessions	Q99MW1	Gene names	Stk31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1).

WRN_HUMAN
θ value	0.813845 (rank : 23)	NC score	0.048378 (rank : 76)
Query Neighborhood Hits	86	Target Neighborhood Hits	132	Shared Neighborhood Hits	6
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

BPA1_MOUSE
θ value	1.06291 (rank : 24)	NC score	0.053443 (rank : 54)
Query Neighborhood Hits	86	Target Neighborhood Hits	1477	Shared Neighborhood Hits	46
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CN145_MOUSE
θ value	1.38821 (rank : 25)	NC score	0.062130 (rank : 21)
Query Neighborhood Hits	86	Target Neighborhood Hits	916	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

KS6A3_HUMAN
θ value	1.38821 (rank : 26)	NC score	0.033163 (rank : 86)
Query Neighborhood Hits	86	Target Neighborhood Hits	859	Shared Neighborhood Hits	23
SwissProt Accessions	P51812, Q4VAP3, Q59H26, Q5JPK8, Q7Z3Z7	Gene names	RPS6KA3, ISPK1, RSK2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1) (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B).

KS6A3_MOUSE
θ value	1.38821 (rank : 27)	NC score	0.033169 (rank : 85)
Query Neighborhood Hits	86	Target Neighborhood Hits	860	Shared Neighborhood Hits	23
SwissProt Accessions	P18654, Q03140, Q8K3J8	Gene names	Rps6ka3, Rps6ka-rs1, Rsk2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1) (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B).

OPTN_HUMAN
θ value	1.38821 (rank : 28)	NC score	0.059234 (rank : 29)
Query Neighborhood Hits	86	Target Neighborhood Hits	827	Shared Neighborhood Hits	36
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

RAI14_HUMAN
θ value	1.38821 (rank : 29)	NC score	0.054988 (rank : 42)
Query Neighborhood Hits	86	Target Neighborhood Hits	1367	Shared Neighborhood Hits	49
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

CCDC7_HUMAN
θ value	1.81305 (rank : 30)	NC score	0.063224 (rank : 18)
Query Neighborhood Hits	86	Target Neighborhood Hits	253	Shared Neighborhood Hits	23
SwissProt Accessions	Q96M83, Q8IVQ0, Q8NEQ0	Gene names	CCDC7
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 7.

IFT81_HUMAN
θ value	1.81305 (rank : 31)	NC score	0.064325 (rank : 16)
Query Neighborhood Hits	86	Target Neighborhood Hits	893	Shared Neighborhood Hits	45
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

KS6A1_HUMAN
θ value	1.81305 (rank : 32)	NC score	0.032814 (rank : 88)
Query Neighborhood Hits	86	Target Neighborhood Hits	854	Shared Neighborhood Hits	24
SwissProt Accessions	Q15418, Q5SVM5, Q5SVM8, Q5SVM9, Q96C05, Q9BQK2	Gene names	RPS6KA1, RSK1
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1) (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A).

KS6A4_HUMAN
θ value	1.81305 (rank : 33)	NC score	0.031627 (rank : 90)
Query Neighborhood Hits	86	Target Neighborhood Hits	868	Shared Neighborhood Hits	23
SwissProt Accessions	O75676, O75585, Q53ES8	Gene names	RPS6KA4, MSK2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear mitogen- and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (Ribosomal protein kinase B) (RSKB).

KS6A4_MOUSE
θ value	1.81305 (rank : 34)	NC score	0.031665 (rank : 89)
Query Neighborhood Hits	86	Target Neighborhood Hits	866	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z2B9, Q91X18	Gene names	Rps6ka4, Msk2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear mitogen- and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (RSK-like protein kinase) (RLSK).

MKNK1_MOUSE
θ value	1.81305 (rank : 35)	NC score	0.031403 (rank : 91)
Query Neighborhood Hits	86	Target Neighborhood Hits	811	Shared Neighborhood Hits	24
SwissProt Accessions	O08605	Gene names	Mknk1, Mnk1
Domain Architecture
Description	MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (Mnk1).

RB6I2_MOUSE
θ value	1.81305 (rank : 36)	NC score	0.063338 (rank : 17)
Query Neighborhood Hits	86	Target Neighborhood Hits	1433	Shared Neighborhood Hits	50
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

3BP1_HUMAN
θ value	2.36792 (rank : 37)	NC score	0.015854 (rank : 116)
Query Neighborhood Hits	86	Target Neighborhood Hits	376	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

CEP72_MOUSE
θ value	2.36792 (rank : 38)	NC score	0.061921 (rank : 22)
Query Neighborhood Hits	86	Target Neighborhood Hits	381	Shared Neighborhood Hits	30
SwissProt Accessions	Q9D3R3, Q8BM53, Q9D0B7	Gene names	Cep72
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 72 kDa (Cep72 protein).

GCC1_HUMAN
θ value	2.36792 (rank : 39)	NC score	0.074150 (rank : 8)
Query Neighborhood Hits	86	Target Neighborhood Hits	887	Shared Neighborhood Hits	43
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

GOGA4_HUMAN
θ value	2.36792 (rank : 40)	NC score	0.055077 (rank : 41)
Query Neighborhood Hits	86	Target Neighborhood Hits	2034	Shared Neighborhood Hits	51
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

K22E_HUMAN
θ value	2.36792 (rank : 41)	NC score	0.029013 (rank : 95)
Query Neighborhood Hits	86	Target Neighborhood Hits	515	Shared Neighborhood Hits	36
SwissProt Accessions	P35908	Gene names	KRT2A, KRT2E
Domain Architecture
Description	Keratin, type II cytoskeletal 2 epidermal (Cytokeratin-2e) (K2e) (CK 2e).

MYH8_MOUSE
θ value	2.36792 (rank : 42)	NC score	0.063134 (rank : 20)
Query Neighborhood Hits	86	Target Neighborhood Hits	1600	Shared Neighborhood Hits	53
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

TBCD4_HUMAN
θ value	2.36792 (rank : 43)	NC score	0.039239 (rank : 80)
Query Neighborhood Hits	86	Target Neighborhood Hits	357	Shared Neighborhood Hits	23
SwissProt Accessions	O60343, Q5W0B9	Gene names	TBC1D4, KIAA0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

TBCD4_MOUSE
θ value	2.36792 (rank : 44)	NC score	0.037640 (rank : 82)
Query Neighborhood Hits	86	Target Neighborhood Hits	276	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BYJ6, Q5DU23, Q66JU2, Q6P2M2, Q8BMH6, Q8BXM2	Gene names	Tbc1d4, Kiaa0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

AKAP9_HUMAN
θ value	3.0926 (rank : 45)	NC score	0.065636 (rank : 13)
Query Neighborhood Hits	86	Target Neighborhood Hits	1710	Shared Neighborhood Hits	56
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

CCD39_HUMAN
θ value	3.0926 (rank : 46)	NC score	0.057663 (rank : 32)
Query Neighborhood Hits	86	Target Neighborhood Hits	868	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

KNTC2_MOUSE
θ value	3.0926 (rank : 47)	NC score	0.055640 (rank : 40)
Query Neighborhood Hits	86	Target Neighborhood Hits	692	Shared Neighborhood Hits	39
SwissProt Accessions	Q9D0F1, Q3TQT6, Q3UWM5, Q99P70	Gene names	Kntc2, Hec1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (Kinetochore-associated protein 2).

MYH1_HUMAN
θ value	3.0926 (rank : 48)	NC score	0.060887 (rank : 24)
Query Neighborhood Hits	86	Target Neighborhood Hits	1478	Shared Neighborhood Hits	53
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

MYH1_MOUSE
θ value	3.0926 (rank : 49)	NC score	0.060580 (rank : 26)
Query Neighborhood Hits	86	Target Neighborhood Hits	1461	Shared Neighborhood Hits	57
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

SPTN5_HUMAN
θ value	3.0926 (rank : 50)	NC score	0.028429 (rank : 98)
Query Neighborhood Hits	86	Target Neighborhood Hits	674	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

UACA_MOUSE
θ value	3.0926 (rank : 51)	NC score	0.059107 (rank : 30)
Query Neighborhood Hits	86	Target Neighborhood Hits	1620	Shared Neighborhood Hits	50
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

ABCB8_HUMAN
θ value	4.03905 (rank : 52)	NC score	0.008105 (rank : 120)
Query Neighborhood Hits	86	Target Neighborhood Hits	91	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NUT2, O95787	Gene names	ABCB8, MABC1
Domain Architecture
Description	ATP-binding cassette sub-family B member 8, mitochondrial precursor (Mitochondrial ATP-binding cassette 1) (M-ABC1).

GOGA3_MOUSE
θ value	4.03905 (rank : 53)	NC score	0.060249 (rank : 27)
Query Neighborhood Hits	86	Target Neighborhood Hits	1437	Shared Neighborhood Hits	50
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

K0999_MOUSE
θ value	4.03905 (rank : 54)	NC score	0.024256 (rank : 104)
Query Neighborhood Hits	86	Target Neighborhood Hits	931	Shared Neighborhood Hits	22
SwissProt Accessions	Q6P4S6, Q641L5, Q66JZ5, Q6ZQ09, Q8K075, Q9CYD5	Gene names	Kiaa0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).

K2C1B_MOUSE
θ value	4.03905 (rank : 55)	NC score	0.024583 (rank : 101)
Query Neighborhood Hits	86	Target Neighborhood Hits	503	Shared Neighborhood Hits	36
SwissProt Accessions	Q6IFZ6	Gene names	Krt1b
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 1b (Type II keratin Kb39) (Embryonic type II keratin-1).

LAMB1_HUMAN
θ value	4.03905 (rank : 56)	NC score	0.033054 (rank : 87)
Query Neighborhood Hits	86	Target Neighborhood Hits	1018	Shared Neighborhood Hits	40
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

STABP_MOUSE
θ value	4.03905 (rank : 57)	NC score	0.043942 (rank : 78)
Query Neighborhood Hits	86	Target Neighborhood Hits	191	Shared Neighborhood Hits	17
SwissProt Accessions	Q9CQ26, Q3UTI9	Gene names	Stambp, Amsh
Domain Architecture	No domain graphic available
Description	STAM-binding protein (EC 3.1.2.15) (Associated molecule with the SH3 domain of STAM).

GRAP1_MOUSE
θ value	5.27518 (rank : 58)	NC score	0.048789 (rank : 75)
Query Neighborhood Hits	86	Target Neighborhood Hits	1234	Shared Neighborhood Hits	47
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

LAMB1_MOUSE
θ value	5.27518 (rank : 59)	NC score	0.029135 (rank : 94)
Query Neighborhood Hits	86	Target Neighborhood Hits	919	Shared Neighborhood Hits	38
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

MYH2_HUMAN
θ value	5.27518 (rank : 60)	NC score	0.061006 (rank : 23)
Query Neighborhood Hits	86	Target Neighborhood Hits	1491	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

RIC8B_HUMAN
θ value	5.27518 (rank : 61)	NC score	0.017156 (rank : 114)
Query Neighborhood Hits	86	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NVN3, Q4G103, Q6ZRN4, Q86WD3	Gene names	RIC8B
Domain Architecture	No domain graphic available
Description	Synembryn-B (Brain synembrin) (hSyn) (Protein Ric-8B).

RNF41_HUMAN
θ value	5.27518 (rank : 62)	NC score	0.021558 (rank : 111)
Query Neighborhood Hits	86	Target Neighborhood Hits	226	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	5.27518 (rank : 63)	NC score	0.021607 (rank : 110)
Query Neighborhood Hits	86	Target Neighborhood Hits	224	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

CCD93_HUMAN
θ value	6.88961 (rank : 64)	NC score	0.052375 (rank : 59)
Query Neighborhood Hits	86	Target Neighborhood Hits	600	Shared Neighborhood Hits	39
SwissProt Accessions	Q567U6, Q4LE78, Q53TJ2, Q8TBX5, Q9H6R5, Q9NV15	Gene names	CCDC93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

CCD93_MOUSE
θ value	6.88961 (rank : 65)	NC score	0.051736 (rank : 63)
Query Neighborhood Hits	86	Target Neighborhood Hits	362	Shared Neighborhood Hits	29
SwissProt Accessions	Q7TQK5, Q3TX53	Gene names	Ccdc93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

COG2_HUMAN
θ value	6.88961 (rank : 66)	NC score	0.018302 (rank : 113)
Query Neighborhood Hits	86	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q14746	Gene names	COG2, LDLC
Domain Architecture
Description	Conserved oligomeric Golgi complex component 2 (Low density lipoprotein receptor defect C-complementing protein).

FER_HUMAN
θ value	6.88961 (rank : 67)	NC score	0.019463 (rank : 112)
Query Neighborhood Hits	86	Target Neighborhood Hits	1278	Shared Neighborhood Hits	50
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

KCC1D_HUMAN
θ value	6.88961 (rank : 68)	NC score	0.022279 (rank : 108)
Query Neighborhood Hits	86	Target Neighborhood Hits	846	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IU85, Q9HD31	Gene names	CAMK1D
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK).

KCC1D_MOUSE
θ value	6.88961 (rank : 69)	NC score	0.022299 (rank : 107)
Query Neighborhood Hits	86	Target Neighborhood Hits	847	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BW96, Q3U450, Q80W64, Q8BWI7	Gene names	Camk1d
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) (mCKLiK).

KS6B1_HUMAN
θ value	6.88961 (rank : 70)	NC score	0.024357 (rank : 103)
Query Neighborhood Hits	86	Target Neighborhood Hits	850	Shared Neighborhood Hits	21
SwissProt Accessions	P23443	Gene names	RPS6KB1
Domain Architecture
Description	Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1) (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) (p70-S6K) (P70S6K) (p70-alpha).

KS6B1_MOUSE
θ value	6.88961 (rank : 71)	NC score	0.024358 (rank : 102)
Query Neighborhood Hits	86	Target Neighborhood Hits	849	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BSK8, Q8CHX0	Gene names	Rps6kb1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1) (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) (p70-S6K) (P70S6K).

MKNK2_HUMAN
θ value	6.88961 (rank : 72)	NC score	0.028625 (rank : 97)
Query Neighborhood Hits	86	Target Neighborhood Hits	821	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HBH9, Q6GPI3, Q9HBH8, Q9UHR0, Q9Y2N6	Gene names	MKNK2, MNK2
Domain Architecture
Description	MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (Mnk2).

NPHP4_MOUSE
θ value	6.88961 (rank : 73)	NC score	0.015900 (rank : 115)
Query Neighborhood Hits	86	Target Neighborhood Hits	62	Shared Neighborhood Hits	2
SwissProt Accessions	P59240	Gene names	Nphp4
Domain Architecture	No domain graphic available
Description	Nephrocystin-4 (Nephroretinin).

OPTN_MOUSE
θ value	6.88961 (rank : 74)	NC score	0.054395 (rank : 46)
Query Neighborhood Hits	86	Target Neighborhood Hits	1120	Shared Neighborhood Hits	44
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

ZC11A_MOUSE
θ value	6.88961 (rank : 75)	NC score	0.026263 (rank : 100)
Query Neighborhood Hits	86	Target Neighborhood Hits	216	Shared Neighborhood Hits	13
SwissProt Accessions	Q6NZF1, Q6NXW9, Q6PDR6, Q80TU7, Q8C5L5, Q99JN6	Gene names	Zc3h11a, Kiaa0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

CASP_MOUSE
θ value	8.99809 (rank : 76)	NC score	0.046713 (rank : 77)
Query Neighborhood Hits	86	Target Neighborhood Hits	1152	Shared Neighborhood Hits	45
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

EEA1_MOUSE
θ value	8.99809 (rank : 77)	NC score	0.051503 (rank : 66)
Query Neighborhood Hits	86	Target Neighborhood Hits	1637	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

GIT2_HUMAN
θ value	8.99809 (rank : 78)	NC score	0.010236 (rank : 119)
Query Neighborhood Hits	86	Target Neighborhood Hits	381	Shared Neighborhood Hits	13
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

KGP2_HUMAN
θ value	8.99809 (rank : 79)	NC score	0.023885 (rank : 105)
Query Neighborhood Hits	86	Target Neighborhood Hits	1023	Shared Neighborhood Hits	39
SwissProt Accessions	Q13237, O00125, O60916	Gene names	PRKG2, PRKGR2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KS6A1_MOUSE
θ value	8.99809 (rank : 80)	NC score	0.030654 (rank : 92)
Query Neighborhood Hits	86	Target Neighborhood Hits	850	Shared Neighborhood Hits	22
SwissProt Accessions	P18653	Gene names	Rps6ka1, Rsk1
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1) (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A).

MKNK2_MOUSE
θ value	8.99809 (rank : 81)	NC score	0.028237 (rank : 99)
Query Neighborhood Hits	86	Target Neighborhood Hits	819	Shared Neighborhood Hits	22
SwissProt Accessions	Q8CDB0, O08606, Q75PY0, Q9D893	Gene names	Mknk2, Mnk2
Domain Architecture
Description	MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (Mnk2).

SMG1_HUMAN
θ value	8.99809 (rank : 82)	NC score	0.021748 (rank : 109)
Query Neighborhood Hits	86	Target Neighborhood Hits	231	Shared Neighborhood Hits	19
SwissProt Accessions	Q96Q15, O43305, Q13284, Q8NFX2, Q96QV0, Q96RW3	Gene names	SMG1, ATX, KIAA0421, LIP
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1) (hSMG-1) (Lambda/iota protein kinase C-interacting protein) (Lambda-interacting protein) (61E3.4).

SMG1_MOUSE
θ value	8.99809 (rank : 83)	NC score	0.022634 (rank : 106)
Query Neighborhood Hits	86	Target Neighborhood Hits	212	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BKX6, Q5DU42, Q6ZQC0, Q8BLU4, Q8BWJ5, Q8BXD3	Gene names	Smg1, Kiaa0421
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1).

STABP_HUMAN
θ value	8.99809 (rank : 84)	NC score	0.037719 (rank : 81)
Query Neighborhood Hits	86	Target Neighborhood Hits	140	Shared Neighborhood Hits	18
SwissProt Accessions	O95630, Q3MJE7	Gene names	STAMBP, AMSH
Domain Architecture	No domain graphic available
Description	STAM-binding protein (EC 3.1.2.15) (Associated molecule with the SH3 domain of STAM).

STRC_MOUSE
θ value	8.99809 (rank : 85)	NC score	0.012089 (rank : 117)
Query Neighborhood Hits	86	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VIM6	Gene names	Strc
Domain Architecture	No domain graphic available
Description	Stereocilin precursor.

TRI65_MOUSE
θ value	8.99809 (rank : 86)	NC score	0.010981 (rank : 118)
Query Neighborhood Hits	86	Target Neighborhood Hits	340	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

BPAEA_MOUSE
θ value	θ > 10 (rank : 87)	NC score	0.053726 (rank : 52)
Query Neighborhood Hits	86	Target Neighborhood Hits	1480	Shared Neighborhood Hits	48
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CCD39_MOUSE
θ value	θ > 10 (rank : 88)	NC score	0.052945 (rank : 57)
Query Neighborhood Hits	86	Target Neighborhood Hits	1026	Shared Neighborhood Hits	42
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CCD41_MOUSE
θ value	θ > 10 (rank : 89)	NC score	0.052248 (rank : 60)
Query Neighborhood Hits	86	Target Neighborhood Hits	1399	Shared Neighborhood Hits	46
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

CE152_HUMAN
θ value	θ > 10 (rank : 90)	NC score	0.051938 (rank : 61)
Query Neighborhood Hits	86	Target Neighborhood Hits	976	Shared Neighborhood Hits	41
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

CE290_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.050807 (rank : 69)
Query Neighborhood Hits	86	Target Neighborhood Hits	1553	Shared Neighborhood Hits	50
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CEP63_HUMAN
θ value	θ > 10 (rank : 92)	NC score	0.050916 (rank : 68)
Query Neighborhood Hits	86	Target Neighborhood Hits	1005	Shared Neighborhood Hits	43
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

CP250_MOUSE
θ value	θ > 10 (rank : 93)	NC score	0.053283 (rank : 56)
Query Neighborhood Hits	86	Target Neighborhood Hits	1583	Shared Neighborhood Hits	50
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

EEA1_HUMAN
θ value	θ > 10 (rank : 94)	NC score	0.051613 (rank : 64)
Query Neighborhood Hits	86	Target Neighborhood Hits	1796	Shared Neighborhood Hits	49
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

ERC2_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.053791 (rank : 51)
Query Neighborhood Hits	86	Target Neighborhood Hits	1156	Shared Neighborhood Hits	47
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

ERC2_MOUSE
θ value	θ > 10 (rank : 96)	NC score	0.053511 (rank : 53)
Query Neighborhood Hits	86	Target Neighborhood Hits	1166	Shared Neighborhood Hits	48
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

GCC2_MOUSE
θ value	θ > 10 (rank : 97)	NC score	0.051180 (rank : 67)
Query Neighborhood Hits	86	Target Neighborhood Hits	1619	Shared Neighborhood Hits	52
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

GOGA2_MOUSE
θ value	θ > 10 (rank : 98)	NC score	0.054815 (rank : 43)
Query Neighborhood Hits	86	Target Neighborhood Hits	944	Shared Neighborhood Hits	44
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

GOGA3_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.050197 (rank : 74)
Query Neighborhood Hits	86	Target Neighborhood Hits	1317	Shared Neighborhood Hits	43
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

GOGA4_MOUSE
θ value	θ > 10 (rank : 100)	NC score	0.054097 (rank : 49)
Query Neighborhood Hits	86	Target Neighborhood Hits	1939	Shared Neighborhood Hits	52
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

GOGB1_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.055674 (rank : 39)
Query Neighborhood Hits	86	Target Neighborhood Hits	2297	Shared Neighborhood Hits	57
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

HMMR_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.053424 (rank : 55)
Query Neighborhood Hits	86	Target Neighborhood Hits	1082	Shared Neighborhood Hits	42
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

IFT81_MOUSE
θ value	θ > 10 (rank : 103)	NC score	0.052539 (rank : 58)
Query Neighborhood Hits	86	Target Neighborhood Hits	959	Shared Neighborhood Hits	43
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

MYH10_HUMAN
θ value	θ > 10 (rank : 104)	NC score	0.050526 (rank : 71)
Query Neighborhood Hits	86	Target Neighborhood Hits	1620	Shared Neighborhood Hits	49
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_MOUSE
θ value	θ > 10 (rank : 105)	NC score	0.050530 (rank : 70)
Query Neighborhood Hits	86	Target Neighborhood Hits	1612	Shared Neighborhood Hits	48
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH11_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.050243 (rank : 73)
Query Neighborhood Hits	86	Target Neighborhood Hits	1806	Shared Neighborhood Hits	50
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH11_MOUSE
θ value	θ > 10 (rank : 107)	NC score	0.050443 (rank : 72)
Query Neighborhood Hits	86	Target Neighborhood Hits	1777	Shared Neighborhood Hits	52
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH3_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.058075 (rank : 31)
Query Neighborhood Hits	86	Target Neighborhood Hits	1660	Shared Neighborhood Hits	52
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

MYH6_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.054702 (rank : 44)
Query Neighborhood Hits	86	Target Neighborhood Hits	1426	Shared Neighborhood Hits	49
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH6_MOUSE
θ value	θ > 10 (rank : 110)	NC score	0.054314 (rank : 47)
Query Neighborhood Hits	86	Target Neighborhood Hits	1501	Shared Neighborhood Hits	50
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH7_HUMAN
θ value	θ > 10 (rank : 111)	NC score	0.053939 (rank : 50)
Query Neighborhood Hits	86	Target Neighborhood Hits	1559	Shared Neighborhood Hits	50
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

MYH8_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.060678 (rank : 25)
Query Neighborhood Hits	86	Target Neighborhood Hits	1610	Shared Neighborhood Hits	56
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH9_HUMAN
θ value	θ > 10 (rank : 113)	NC score	0.056269 (rank : 36)
Query Neighborhood Hits	86	Target Neighborhood Hits	1762	Shared Neighborhood Hits	51
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH9_MOUSE
θ value	θ > 10 (rank : 114)	NC score	0.056811 (rank : 35)
Query Neighborhood Hits	86	Target Neighborhood Hits	1829	Shared Neighborhood Hits	53
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYO5A_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.057540 (rank : 33)
Query Neighborhood Hits	86	Target Neighborhood Hits	1092	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

NUMA1_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.055839 (rank : 38)
Query Neighborhood Hits	86	Target Neighborhood Hits	1523	Shared Neighborhood Hits	49
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

SYCP1_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.051544 (rank : 65)
Query Neighborhood Hits	86	Target Neighborhood Hits	1313	Shared Neighborhood Hits	52
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

TPR_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.056170 (rank : 37)
Query Neighborhood Hits	86	Target Neighborhood Hits	1921	Shared Neighborhood Hits	54
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

TRIPB_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.051826 (rank : 62)
Query Neighborhood Hits	86	Target Neighborhood Hits	1587	Shared Neighborhood Hits	48
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

UACA_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.054186 (rank : 48)
Query Neighborhood Hits	86	Target Neighborhood Hits	1622	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

Hits sorted by NC score

ZW10_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	86	Target Neighborhood Hits	86	Shared Neighborhood Hits	86
SwissProt Accessions	O54692, Q3TIA5, Q3ULW1, Q921H3	Gene names	Zw10
Domain Architecture	No domain graphic available
Description	Centromere/kinetochore protein zw10 homolog.

ZW10_HUMAN
NC score	0.955531 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	86	Target Neighborhood Hits	101	Shared Neighborhood Hits	43
SwissProt Accessions	O43264	Gene names	ZW10
Domain Architecture
Description	Centromere/kinetochore protein zw10 homolog.

EXOC4_MOUSE
NC score	0.153410 (rank : 3)	θ value	0.00134147 (rank : 4)
Query Neighborhood Hits	86	Target Neighborhood Hits	86	Shared Neighborhood Hits	16
SwissProt Accessions	O35382	Gene names	Exoc4, Sec8, Sec8l1
Domain Architecture
Description	Exocyst complex component 4 (Exocyst complex component Sec8).

EXOC4_HUMAN
NC score	0.153233 (rank : 4)	θ value	0.00134147 (rank : 3)
Query Neighborhood Hits	86	Target Neighborhood Hits	72	Shared Neighborhood Hits	13
SwissProt Accessions	Q96A65, Q9C0G4, Q9H9K0, Q9P102	Gene names	EXOC4, KIAA1699, SEC8, SEC8L1
Domain Architecture
Description	Exocyst complex component 4 (Exocyst complex component Sec8).

GCC1_MOUSE
NC score	0.090294 (rank : 5)	θ value	0.163984 (rank : 12)
Query Neighborhood Hits	86	Target Neighborhood Hits	777	Shared Neighborhood Hits	42
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

CENPF_HUMAN
NC score	0.083973 (rank : 6)	θ value	0.0113563 (rank : 5)
Query Neighborhood Hits	86	Target Neighborhood Hits	1932	Shared Neighborhood Hits	55
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

STK31_MOUSE
NC score	0.075140 (rank : 7)	θ value	0.47712 (rank : 22)
Query Neighborhood Hits	86	Target Neighborhood Hits	474	Shared Neighborhood Hits	30
SwissProt Accessions	Q99MW1	Gene names	Stk31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1).

GCC1_HUMAN
NC score	0.074150 (rank : 8)	θ value	2.36792 (rank : 39)
Query Neighborhood Hits	86	Target Neighborhood Hits	887	Shared Neighborhood Hits	43
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

STK31_HUMAN
NC score	0.073555 (rank : 9)	θ value	0.163984 (rank : 15)
Query Neighborhood Hits	86	Target Neighborhood Hits	570	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BXU1, Q9BXH8	Gene names	STK31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1) (Serine/threonine- protein kinase NYD-SPK).

MYH4_HUMAN
NC score	0.067564 (rank : 10)	θ value	0.279714 (rank : 18)
Query Neighborhood Hits	86	Target Neighborhood Hits	1377	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

CENPE_HUMAN
NC score	0.067228 (rank : 11)	θ value	0.125558 (rank : 9)
Query Neighborhood Hits	86	Target Neighborhood Hits	2060	Shared Neighborhood Hits	57
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

GOGA2_HUMAN
NC score	0.066327 (rank : 12)	θ value	0.125558 (rank : 10)
Query Neighborhood Hits	86	Target Neighborhood Hits	856	Shared Neighborhood Hits	39
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

AKAP9_HUMAN
NC score	0.065636 (rank : 13)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	86	Target Neighborhood Hits	1710	Shared Neighborhood Hits	56
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

MYH4_MOUSE
NC score	0.064995 (rank : 14)	θ value	0.365318 (rank : 21)
Query Neighborhood Hits	86	Target Neighborhood Hits	1476	Shared Neighborhood Hits	53
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

RB6I2_HUMAN
NC score	0.064624 (rank : 15)	θ value	0.163984 (rank : 14)
Query Neighborhood Hits	86	Target Neighborhood Hits	1584	Shared Neighborhood Hits	50
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

IFT81_HUMAN
NC score	0.064325 (rank : 16)	θ value	1.81305 (rank : 31)
Query Neighborhood Hits	86	Target Neighborhood Hits	893	Shared Neighborhood Hits	45
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

RB6I2_MOUSE
NC score	0.063338 (rank : 17)	θ value	1.81305 (rank : 36)
Query Neighborhood Hits	86	Target Neighborhood Hits	1433	Shared Neighborhood Hits	50
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

CCDC7_HUMAN
NC score	0.063224 (rank : 18)	θ value	1.81305 (rank : 30)
Query Neighborhood Hits	86	Target Neighborhood Hits	253	Shared Neighborhood Hits	23
SwissProt Accessions	Q96M83, Q8IVQ0, Q8NEQ0	Gene names	CCDC7
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 7.

MYH13_HUMAN
NC score	0.063149 (rank : 19)	θ value	0.125558 (rank : 11)
Query Neighborhood Hits	86	Target Neighborhood Hits	1504	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

MYH8_MOUSE
NC score	0.063134 (rank : 20)	θ value	2.36792 (rank : 42)
Query Neighborhood Hits	86	Target Neighborhood Hits	1600	Shared Neighborhood Hits	53
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

CN145_MOUSE
NC score	0.062130 (rank : 21)	θ value	1.38821 (rank : 25)
Query Neighborhood Hits	86	Target Neighborhood Hits	916	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

CEP72_MOUSE
NC score	0.061921 (rank : 22)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	86	Target Neighborhood Hits	381	Shared Neighborhood Hits	30
SwissProt Accessions	Q9D3R3, Q8BM53, Q9D0B7	Gene names	Cep72
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 72 kDa (Cep72 protein).

MYH2_HUMAN
NC score	0.061006 (rank : 23)	θ value	5.27518 (rank : 60)
Query Neighborhood Hits	86	Target Neighborhood Hits	1491	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

MYH1_HUMAN
NC score	0.060887 (rank : 24)	θ value	3.0926 (rank : 48)
Query Neighborhood Hits	86	Target Neighborhood Hits	1478	Shared Neighborhood Hits	53
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

MYH8_HUMAN
NC score	0.060678 (rank : 25)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	86	Target Neighborhood Hits	1610	Shared Neighborhood Hits	56
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH1_MOUSE
NC score	0.060580 (rank : 26)	θ value	3.0926 (rank : 49)
Query Neighborhood Hits	86	Target Neighborhood Hits	1461	Shared Neighborhood Hits	57
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

GOGA3_MOUSE
NC score	0.060249 (rank : 27)	θ value	4.03905 (rank : 53)
Query Neighborhood Hits	86	Target Neighborhood Hits	1437	Shared Neighborhood Hits	50
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

CP250_HUMAN
NC score	0.059585 (rank : 28)	θ value	0.21417 (rank : 16)
Query Neighborhood Hits	86	Target Neighborhood Hits	1805	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

OPTN_HUMAN
NC score	0.059234 (rank : 29)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	86	Target Neighborhood Hits	827	Shared Neighborhood Hits	36
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

UACA_MOUSE
NC score	0.059107 (rank : 30)	θ value	3.0926 (rank : 51)
Query Neighborhood Hits	86	Target Neighborhood Hits	1620	Shared Neighborhood Hits	50
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

MYH3_HUMAN
NC score	0.058075 (rank : 31)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	86	Target Neighborhood Hits	1660	Shared Neighborhood Hits	52
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

CCD39_HUMAN
NC score	0.057663 (rank : 32)	θ value	3.0926 (rank : 46)
Query Neighborhood Hits	86	Target Neighborhood Hits	868	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

MYO5A_HUMAN
NC score	0.057540 (rank : 33)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	86	Target Neighborhood Hits	1092	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

WRN_MOUSE
NC score	0.056813 (rank : 34)	θ value	0.0961366 (rank : 8)
Query Neighborhood Hits	86	Target Neighborhood Hits	295	Shared Neighborhood Hits	12
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

MYH9_MOUSE
NC score	0.056811 (rank : 35)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	86	Target Neighborhood Hits	1829	Shared Neighborhood Hits	53
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH9_HUMAN
NC score	0.056269 (rank : 36)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	86	Target Neighborhood Hits	1762	Shared Neighborhood Hits	51
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

TPR_HUMAN
NC score	0.056170 (rank : 37)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	86	Target Neighborhood Hits	1921	Shared Neighborhood Hits	54
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

NUMA1_HUMAN
NC score	0.055839 (rank : 38)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	86	Target Neighborhood Hits	1523	Shared Neighborhood Hits	49
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

GOGB1_HUMAN
NC score	0.055674 (rank : 39)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	86	Target Neighborhood Hits	2297	Shared Neighborhood Hits	57
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

KNTC2_MOUSE
NC score	0.055640 (rank : 40)	θ value	3.0926 (rank : 47)
Query Neighborhood Hits	86	Target Neighborhood Hits	692	Shared Neighborhood Hits	39
SwissProt Accessions	Q9D0F1, Q3TQT6, Q3UWM5, Q99P70	Gene names	Kntc2, Hec1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (Kinetochore-associated protein 2).

GOGA4_HUMAN
NC score	0.055077 (rank : 41)	θ value	2.36792 (rank : 40)
Query Neighborhood Hits	86	Target Neighborhood Hits	2034	Shared Neighborhood Hits	51
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

RAI14_HUMAN
NC score	0.054988 (rank : 42)	θ value	1.38821 (rank : 29)
Query Neighborhood Hits	86	Target Neighborhood Hits	1367	Shared Neighborhood Hits	49
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

GOGA2_MOUSE
NC score	0.054815 (rank : 43)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	86	Target Neighborhood Hits	944	Shared Neighborhood Hits	44
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

MYH6_HUMAN
NC score	0.054702 (rank : 44)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	86	Target Neighborhood Hits	1426	Shared Neighborhood Hits	49
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYO5A_MOUSE
NC score	0.054520 (rank : 45)	θ value	0.163984 (rank : 13)
Query Neighborhood Hits	86	Target Neighborhood Hits	1117	Shared Neighborhood Hits	43
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

OPTN_MOUSE
NC score	0.054395 (rank : 46)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	86	Target Neighborhood Hits	1120	Shared Neighborhood Hits	44
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

MYH6_MOUSE
NC score	0.054314 (rank : 47)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	86	Target Neighborhood Hits	1501	Shared Neighborhood Hits	50
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

UACA_HUMAN
NC score	0.054186 (rank : 48)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	86	Target Neighborhood Hits	1622	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

GOGA4_MOUSE
NC score	0.054097 (rank : 49)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	86	Target Neighborhood Hits	1939	Shared Neighborhood Hits	52
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

MYH7_HUMAN
NC score	0.053939 (rank : 50)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	86	Target Neighborhood Hits	1559	Shared Neighborhood Hits	50
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

ERC2_HUMAN
NC score	0.053791 (rank : 51)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	86	Target Neighborhood Hits	1156	Shared Neighborhood Hits	47
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

BPAEA_MOUSE
NC score	0.053726 (rank : 52)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	86	Target Neighborhood Hits	1480	Shared Neighborhood Hits	48
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

ERC2_MOUSE
NC score	0.053511 (rank : 53)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	86	Target Neighborhood Hits	1166	Shared Neighborhood Hits	48
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

BPA1_MOUSE
NC score	0.053443 (rank : 54)	θ value	1.06291 (rank : 24)
Query Neighborhood Hits	86	Target Neighborhood Hits	1477	Shared Neighborhood Hits	46
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

HMMR_HUMAN
NC score	0.053424 (rank : 55)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	86	Target Neighborhood Hits	1082	Shared Neighborhood Hits	42
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

CP250_MOUSE
NC score	0.053283 (rank : 56)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	86	Target Neighborhood Hits	1583	Shared Neighborhood Hits	50
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

CCD39_MOUSE
NC score	0.052945 (rank : 57)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	86	Target Neighborhood Hits	1026	Shared Neighborhood Hits	42
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

IFT81_MOUSE
NC score	0.052539 (rank : 58)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	86	Target Neighborhood Hits	959	Shared Neighborhood Hits	43
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

CCD93_HUMAN
NC score	0.052375 (rank : 59)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	86	Target Neighborhood Hits	600	Shared Neighborhood Hits	39
SwissProt Accessions	Q567U6, Q4LE78, Q53TJ2, Q8TBX5, Q9H6R5, Q9NV15	Gene names	CCDC93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

CCD41_MOUSE
NC score	0.052248 (rank : 60)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	86	Target Neighborhood Hits	1399	Shared Neighborhood Hits	46
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

CE152_HUMAN
NC score	0.051938 (rank : 61)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	86	Target Neighborhood Hits	976	Shared Neighborhood Hits	41
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

TRIPB_HUMAN
NC score	0.051826 (rank : 62)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	86	Target Neighborhood Hits	1587	Shared Neighborhood Hits	48
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

CCD93_MOUSE
NC score	0.051736 (rank : 63)	θ value	6.88961 (rank : 65)
Query Neighborhood Hits	86	Target Neighborhood Hits	362	Shared Neighborhood Hits	29
SwissProt Accessions	Q7TQK5, Q3TX53	Gene names	Ccdc93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

EEA1_HUMAN
NC score	0.051613 (rank : 64)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	86	Target Neighborhood Hits	1796	Shared Neighborhood Hits	49
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

SYCP1_HUMAN
NC score	0.051544 (rank : 65)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	86	Target Neighborhood Hits	1313	Shared Neighborhood Hits	52
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

EEA1_MOUSE
NC score	0.051503 (rank : 66)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	86	Target Neighborhood Hits	1637	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

GCC2_MOUSE
NC score	0.051180 (rank : 67)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	86	Target Neighborhood Hits	1619	Shared Neighborhood Hits	52
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

CEP63_HUMAN
NC score	0.050916 (rank : 68)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	86	Target Neighborhood Hits	1005	Shared Neighborhood Hits	43
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

CE290_HUMAN
NC score	0.050807 (rank : 69)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	86	Target Neighborhood Hits	1553	Shared Neighborhood Hits	50
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

MYH10_MOUSE
NC score	0.050530 (rank : 70)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	86	Target Neighborhood Hits	1612	Shared Neighborhood Hits	48
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_HUMAN
NC score	0.050526 (rank : 71)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	86	Target Neighborhood Hits	1620	Shared Neighborhood Hits	49
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH11_MOUSE
NC score	0.050443 (rank : 72)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	86	Target Neighborhood Hits	1777	Shared Neighborhood Hits	52
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH11_HUMAN
NC score	0.050243 (rank : 73)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	86	Target Neighborhood Hits	1806	Shared Neighborhood Hits	50
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

GOGA3_HUMAN
NC score	0.050197 (rank : 74)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	86	Target Neighborhood Hits	1317	Shared Neighborhood Hits	43
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

GRAP1_MOUSE
NC score	0.048789 (rank : 75)	θ value	5.27518 (rank : 58)
Query Neighborhood Hits	86	Target Neighborhood Hits	1234	Shared Neighborhood Hits	47
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

WRN_HUMAN
NC score	0.048378 (rank : 76)	θ value	0.813845 (rank : 23)
Query Neighborhood Hits	86	Target Neighborhood Hits	132	Shared Neighborhood Hits	6
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

CASP_MOUSE
NC score	0.046713 (rank : 77)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	86	Target Neighborhood Hits	1152	Shared Neighborhood Hits	45
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

STABP_MOUSE
NC score	0.043942 (rank : 78)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	86	Target Neighborhood Hits	191	Shared Neighborhood Hits	17
SwissProt Accessions	Q9CQ26, Q3UTI9	Gene names	Stambp, Amsh
Domain Architecture	No domain graphic available
Description	STAM-binding protein (EC 3.1.2.15) (Associated molecule with the SH3 domain of STAM).

KS6A2_MOUSE
NC score	0.039323 (rank : 79)	θ value	0.0193708 (rank : 6)
Query Neighborhood Hits	86	Target Neighborhood Hits	858	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WUT3, Q9D2C0	Gene names	Rps6ka2, Rsk3
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1) (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase- activated protein kinase 1c) (MAPKAPK1C).

TBCD4_HUMAN
NC score	0.039239 (rank : 80)	θ value	2.36792 (rank : 43)
Query Neighborhood Hits	86	Target Neighborhood Hits	357	Shared Neighborhood Hits	23
SwissProt Accessions	O60343, Q5W0B9	Gene names	TBC1D4, KIAA0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

STABP_HUMAN
NC score	0.037719 (rank : 81)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	86	Target Neighborhood Hits	140	Shared Neighborhood Hits	18
SwissProt Accessions	O95630, Q3MJE7	Gene names	STAMBP, AMSH
Domain Architecture	No domain graphic available
Description	STAM-binding protein (EC 3.1.2.15) (Associated molecule with the SH3 domain of STAM).

TBCD4_MOUSE
NC score	0.037640 (rank : 82)	θ value	2.36792 (rank : 44)
Query Neighborhood Hits	86	Target Neighborhood Hits	276	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BYJ6, Q5DU23, Q66JU2, Q6P2M2, Q8BMH6, Q8BXM2	Gene names	Tbc1d4, Kiaa0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

KS6A2_HUMAN
NC score	0.036970 (rank : 83)	θ value	0.0961366 (rank : 7)
Query Neighborhood Hits	86	Target Neighborhood Hits	857	Shared Neighborhood Hits	22
SwissProt Accessions	Q15349, Q15419, Q59GJ3, Q5TI68, Q96J38, Q9UJN5	Gene names	RPS6KA2, RSK3
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1) (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C).

KS6A6_HUMAN
NC score	0.035877 (rank : 84)	θ value	0.365318 (rank : 20)
Query Neighborhood Hits	86	Target Neighborhood Hits	853	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UK32, Q8WX28, Q9H4S6	Gene names	RPS6KA6, RSK4
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1) (S6K-alpha 6) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4).

KS6A3_MOUSE
NC score	0.033169 (rank : 85)	θ value	1.38821 (rank : 27)
Query Neighborhood Hits	86	Target Neighborhood Hits	860	Shared Neighborhood Hits	23
SwissProt Accessions	P18654, Q03140, Q8K3J8	Gene names	Rps6ka3, Rps6ka-rs1, Rsk2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1) (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B).

KS6A3_HUMAN
NC score	0.033163 (rank : 86)	θ value	1.38821 (rank : 26)
Query Neighborhood Hits	86	Target Neighborhood Hits	859	Shared Neighborhood Hits	23
SwissProt Accessions	P51812, Q4VAP3, Q59H26, Q5JPK8, Q7Z3Z7	Gene names	RPS6KA3, ISPK1, RSK2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1) (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B).

LAMB1_HUMAN
NC score	0.033054 (rank : 87)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	86	Target Neighborhood Hits	1018	Shared Neighborhood Hits	40
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

KS6A1_HUMAN
NC score	0.032814 (rank : 88)	θ value	1.81305 (rank : 32)
Query Neighborhood Hits	86	Target Neighborhood Hits	854	Shared Neighborhood Hits	24
SwissProt Accessions	Q15418, Q5SVM5, Q5SVM8, Q5SVM9, Q96C05, Q9BQK2	Gene names	RPS6KA1, RSK1
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1) (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A).

KS6A4_MOUSE
NC score	0.031665 (rank : 89)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	86	Target Neighborhood Hits	866	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z2B9, Q91X18	Gene names	Rps6ka4, Msk2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear mitogen- and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (RSK-like protein kinase) (RLSK).

KS6A4_HUMAN
NC score	0.031627 (rank : 90)	θ value	1.81305 (rank : 33)
Query Neighborhood Hits	86	Target Neighborhood Hits	868	Shared Neighborhood Hits	23
SwissProt Accessions	O75676, O75585, Q53ES8	Gene names	RPS6KA4, MSK2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear mitogen- and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (Ribosomal protein kinase B) (RSKB).

MKNK1_MOUSE
NC score	0.031403 (rank : 91)	θ value	1.81305 (rank : 35)
Query Neighborhood Hits	86	Target Neighborhood Hits	811	Shared Neighborhood Hits	24
SwissProt Accessions	O08605	Gene names	Mknk1, Mnk1
Domain Architecture
Description	MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (Mnk1).

KS6A1_MOUSE
NC score	0.030654 (rank : 92)	θ value	8.99809 (rank : 80)
Query Neighborhood Hits	86	Target Neighborhood Hits	850	Shared Neighborhood Hits	22
SwissProt Accessions	P18653	Gene names	Rps6ka1, Rsk1
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1) (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A).

TRI15_HUMAN
NC score	0.029405 (rank : 93)	θ value	0.279714 (rank : 19)
Query Neighborhood Hits	86	Target Neighborhood Hits	395	Shared Neighborhood Hits	21
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

LAMB1_MOUSE
NC score	0.029135 (rank : 94)	θ value	5.27518 (rank : 59)
Query Neighborhood Hits	86	Target Neighborhood Hits	919	Shared Neighborhood Hits	38
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

K22E_HUMAN
NC score	0.029013 (rank : 95)	θ value	2.36792 (rank : 41)
Query Neighborhood Hits	86	Target Neighborhood Hits	515	Shared Neighborhood Hits	36
SwissProt Accessions	P35908	Gene names	KRT2A, KRT2E
Domain Architecture
Description	Keratin, type II cytoskeletal 2 epidermal (Cytokeratin-2e) (K2e) (CK 2e).

K0999_HUMAN
NC score	0.028755 (rank : 96)	θ value	0.279714 (rank : 17)
Query Neighborhood Hits	86	Target Neighborhood Hits	899	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y2K2, Q59FY2, Q5M9N1, Q6P3R6, Q8IYM8, Q9HA50	Gene names	KIAA0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).

MKNK2_HUMAN
NC score	0.028625 (rank : 97)	θ value	6.88961 (rank : 72)
Query Neighborhood Hits	86	Target Neighborhood Hits	821	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HBH9, Q6GPI3, Q9HBH8, Q9UHR0, Q9Y2N6	Gene names	MKNK2, MNK2
Domain Architecture
Description	MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (Mnk2).

SPTN5_HUMAN
NC score	0.028429 (rank : 98)	θ value	3.0926 (rank : 50)
Query Neighborhood Hits	86	Target Neighborhood Hits	674	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

MKNK2_MOUSE
NC score	0.028237 (rank : 99)	θ value	8.99809 (rank : 81)
Query Neighborhood Hits	86	Target Neighborhood Hits	819	Shared Neighborhood Hits	22
SwissProt Accessions	Q8CDB0, O08606, Q75PY0, Q9D893	Gene names	Mknk2, Mnk2
Domain Architecture
Description	MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (Mnk2).

ZC11A_MOUSE
NC score	0.026263 (rank : 100)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	86	Target Neighborhood Hits	216	Shared Neighborhood Hits	13
SwissProt Accessions	Q6NZF1, Q6NXW9, Q6PDR6, Q80TU7, Q8C5L5, Q99JN6	Gene names	Zc3h11a, Kiaa0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

K2C1B_MOUSE
NC score	0.024583 (rank : 101)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	86	Target Neighborhood Hits	503	Shared Neighborhood Hits	36
SwissProt Accessions	Q6IFZ6	Gene names	Krt1b
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 1b (Type II keratin Kb39) (Embryonic type II keratin-1).

KS6B1_MOUSE
NC score	0.024358 (rank : 102)	θ value	6.88961 (rank : 71)
Query Neighborhood Hits	86	Target Neighborhood Hits	849	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BSK8, Q8CHX0	Gene names	Rps6kb1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1) (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) (p70-S6K) (P70S6K).

KS6B1_HUMAN
NC score	0.024357 (rank : 103)	θ value	6.88961 (rank : 70)
Query Neighborhood Hits	86	Target Neighborhood Hits	850	Shared Neighborhood Hits	21
SwissProt Accessions	P23443	Gene names	RPS6KB1
Domain Architecture
Description	Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1) (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) (p70-S6K) (P70S6K) (p70-alpha).

K0999_MOUSE
NC score	0.024256 (rank : 104)	θ value	4.03905 (rank : 54)
Query Neighborhood Hits	86	Target Neighborhood Hits	931	Shared Neighborhood Hits	22
SwissProt Accessions	Q6P4S6, Q641L5, Q66JZ5, Q6ZQ09, Q8K075, Q9CYD5	Gene names	Kiaa0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).

KGP2_HUMAN
NC score	0.023885 (rank : 105)	θ value	8.99809 (rank : 79)
Query Neighborhood Hits	86	Target Neighborhood Hits	1023	Shared Neighborhood Hits	39
SwissProt Accessions	Q13237, O00125, O60916	Gene names	PRKG2, PRKGR2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

SMG1_MOUSE
NC score	0.022634 (rank : 106)	θ value	8.99809 (rank : 83)
Query Neighborhood Hits	86	Target Neighborhood Hits	212	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BKX6, Q5DU42, Q6ZQC0, Q8BLU4, Q8BWJ5, Q8BXD3	Gene names	Smg1, Kiaa0421
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1).

KCC1D_MOUSE
NC score	0.022299 (rank : 107)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	86	Target Neighborhood Hits	847	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BW96, Q3U450, Q80W64, Q8BWI7	Gene names	Camk1d
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) (mCKLiK).

KCC1D_HUMAN
NC score	0.022279 (rank : 108)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	86	Target Neighborhood Hits	846	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IU85, Q9HD31	Gene names	CAMK1D
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK).

SMG1_HUMAN
NC score	0.021748 (rank : 109)	θ value	8.99809 (rank : 82)
Query Neighborhood Hits	86	Target Neighborhood Hits	231	Shared Neighborhood Hits	19
SwissProt Accessions	Q96Q15, O43305, Q13284, Q8NFX2, Q96QV0, Q96RW3	Gene names	SMG1, ATX, KIAA0421, LIP
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1) (hSMG-1) (Lambda/iota protein kinase C-interacting protein) (Lambda-interacting protein) (61E3.4).

RNF41_MOUSE
NC score	0.021607 (rank : 110)	θ value	5.27518 (rank : 63)
Query Neighborhood Hits	86	Target Neighborhood Hits	224	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_HUMAN
NC score	0.021558 (rank : 111)	θ value	5.27518 (rank : 62)
Query Neighborhood Hits	86	Target Neighborhood Hits	226	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

FER_HUMAN
NC score	0.019463 (rank : 112)	θ value	6.88961 (rank : 67)
Query Neighborhood Hits	86	Target Neighborhood Hits	1278	Shared Neighborhood Hits	50
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

COG2_HUMAN
NC score	0.018302 (rank : 113)	θ value	6.88961 (rank : 66)
Query Neighborhood Hits	86	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q14746	Gene names	COG2, LDLC
Domain Architecture
Description	Conserved oligomeric Golgi complex component 2 (Low density lipoprotein receptor defect C-complementing protein).

RIC8B_HUMAN
NC score	0.017156 (rank : 114)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	86	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NVN3, Q4G103, Q6ZRN4, Q86WD3	Gene names	RIC8B
Domain Architecture	No domain graphic available
Description	Synembryn-B (Brain synembrin) (hSyn) (Protein Ric-8B).

NPHP4_MOUSE
NC score	0.015900 (rank : 115)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	86	Target Neighborhood Hits	62	Shared Neighborhood Hits	2
SwissProt Accessions	P59240	Gene names	Nphp4
Domain Architecture	No domain graphic available
Description	Nephrocystin-4 (Nephroretinin).

3BP1_HUMAN
NC score	0.015854 (rank : 116)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	86	Target Neighborhood Hits	376	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

STRC_MOUSE
NC score	0.012089 (rank : 117)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	86	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VIM6	Gene names	Strc
Domain Architecture	No domain graphic available
Description	Stereocilin precursor.

TRI65_MOUSE
NC score	0.010981 (rank : 118)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	86	Target Neighborhood Hits	340	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

GIT2_HUMAN
NC score	0.010236 (rank : 119)	θ value	8.99809 (rank : 78)
Query Neighborhood Hits	86	Target Neighborhood Hits	381	Shared Neighborhood Hits	13
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

ABCB8_HUMAN
NC score	0.008105 (rank : 120)	θ value	4.03905 (rank : 52)
Query Neighborhood Hits	86	Target Neighborhood Hits	91	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NUT2, O95787	Gene names	ABCB8, MABC1
Domain Architecture
Description	ATP-binding cassette sub-family B member 8, mitochondrial precursor (Mitochondrial ATP-binding cassette 1) (M-ABC1).