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Network neighborhood for query Sequence : F10A5_HUMAN

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F10A5_HUMAN
SwissProt Accessions	Q8NFI4	Gene names	FAM10A5
Domain Architecture	No domain graphic available
Description	Protein FAM10A5.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

F10A5_HUMAN
θ value	2.49938e-159 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	277	Target Neighborhood Hits	277	Shared Neighborhood Hits	277
SwissProt Accessions	Q8NFI4	Gene names	FAM10A5
Domain Architecture	No domain graphic available
Description	Protein FAM10A5.

F10A1_HUMAN
θ value	9.82853e-156 (rank : 2)	NC score	0.985883 (rank : 2)
Query Neighborhood Hits	277	Target Neighborhood Hits	312	Shared Neighborhood Hits	241
SwissProt Accessions	P50502, O14999	Gene names	ST13, FAM10A1, HIP, SNC6
Domain Architecture
Description	Hsc70-interacting protein (Hip) (Suppression of tumorigenicity protein 13) (Putative tumor suppressor ST13) (Protein FAM10A1) (Progesterone receptor-associated p48 protein) (NY-REN-33 antigen).

F10A1_MOUSE
θ value	1.33764e-128 (rank : 3)	NC score	0.948688 (rank : 4)
Query Neighborhood Hits	277	Target Neighborhood Hits	117	Shared Neighborhood Hits	80
SwissProt Accessions	Q99L47, Q4FJT4	Gene names	St13, Fam10a1, Hip
Domain Architecture
Description	Hsc70-interacting protein (Hip) (Protein ST13 homolog) (Protein FAM10A1).

F10A4_HUMAN
θ value	3.4095e-124 (rank : 4)	NC score	0.962810 (rank : 3)
Query Neighborhood Hits	277	Target Neighborhood Hits	249	Shared Neighborhood Hits	172
SwissProt Accessions	Q8IZP2	Gene names	FAM10A4
Domain Architecture	No domain graphic available
Description	Protein FAM10A4.

SPAG1_HUMAN
θ value	2.0648e-12 (rank : 5)	NC score	0.550456 (rank : 11)
Query Neighborhood Hits	277	Target Neighborhood Hits	197	Shared Neighborhood Hits	70
SwissProt Accessions	Q07617, Q7Z5G1	Gene names	SPAG1
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 1 (Infertility-related sperm protein Spag-1) (HSD-3.8).

TOM70_HUMAN
θ value	9.59137e-10 (rank : 6)	NC score	0.561477 (rank : 9)
Query Neighborhood Hits	277	Target Neighborhood Hits	127	Shared Neighborhood Hits	59
SwissProt Accessions	O94826	Gene names	TOMM70A, KIAA0719
Domain Architecture
Description	Mitochondrial precursor proteins import receptor (Translocase of outer membrane TOM70).

TOM70_MOUSE
θ value	1.25267e-09 (rank : 7)	NC score	0.563849 (rank : 8)
Query Neighborhood Hits	277	Target Neighborhood Hits	102	Shared Neighborhood Hits	56
SwissProt Accessions	Q9CZW5	Gene names	Tomm70a, D16Wsu109e
Domain Architecture
Description	Mitochondrial precursor proteins import receptor (Translocase of outer membrane TOM70).

SGTA_MOUSE
θ value	2.13673e-09 (rank : 8)	NC score	0.570454 (rank : 5)
Query Neighborhood Hits	277	Target Neighborhood Hits	112	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BJU0, Q8BGA6, Q99L52	Gene names	Sgta, Sgt
Domain Architecture
Description	Small glutamine-rich tetratricopeptide repeat-containing protein A.

SPAG1_MOUSE
θ value	2.13673e-09 (rank : 9)	NC score	0.539591 (rank : 14)
Query Neighborhood Hits	277	Target Neighborhood Hits	218	Shared Neighborhood Hits	81
SwissProt Accessions	Q80ZX8, Q8CCK7, Q9QZJ3, Q9QZJ4	Gene names	Spag1, Tpis
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 1 (Infertility-related sperm protein Spag-1) (TPR-containing protein involved in spermatogenesis) (TPIS).

SGTB_HUMAN
θ value	4.76016e-09 (rank : 10)	NC score	0.565784 (rank : 6)
Query Neighborhood Hits	277	Target Neighborhood Hits	96	Shared Neighborhood Hits	59
SwissProt Accessions	Q96EQ0	Gene names	SGTB, SGT2
Domain Architecture
Description	Small glutamine-rich tetratricopeptide repeat-containing protein B (Small glutamine-rich protein with tetratricopeptide repeats 2).

SGTB_MOUSE
θ value	1.38499e-08 (rank : 11)	NC score	0.565385 (rank : 7)
Query Neighborhood Hits	277	Target Neighborhood Hits	90	Shared Neighborhood Hits	58
SwissProt Accessions	Q8VD33	Gene names	Sgtb
Domain Architecture	No domain graphic available
Description	Small glutamine-rich tetratricopeptide repeat-containing protein B.

TTC1_MOUSE
θ value	4.0297e-08 (rank : 12)	NC score	0.552153 (rank : 10)
Query Neighborhood Hits	277	Target Neighborhood Hits	145	Shared Neighborhood Hits	63
SwissProt Accessions	Q91Z38, Q3TLM0	Gene names	Ttc1
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

STIP1_MOUSE
θ value	2.61198e-07 (rank : 13)	NC score	0.523283 (rank : 17)
Query Neighborhood Hits	277	Target Neighborhood Hits	154	Shared Neighborhood Hits	61
SwissProt Accessions	Q60864, Q3TT16, Q8BPH3, Q99L66	Gene names	Stip1
Domain Architecture	No domain graphic available
Description	Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (mSTI1).

STUB1_MOUSE
θ value	2.61198e-07 (rank : 14)	NC score	0.545517 (rank : 12)
Query Neighborhood Hits	277	Target Neighborhood Hits	97	Shared Neighborhood Hits	57
SwissProt Accessions	Q9WUD1, Q9DCJ0	Gene names	Stub1, Chip
Domain Architecture	No domain graphic available
Description	STIP1 homology and U box-containing protein 1 (EC 6.3.2.-) (STIP1 homology and U-box-containing protein 1) (Carboxy terminus of Hsp70- interacting protein) (E3 ubiquitin protein ligase CHIP).

PPP5_HUMAN
θ value	3.41135e-07 (rank : 15)	NC score	0.318817 (rank : 31)
Query Neighborhood Hits	277	Target Neighborhood Hits	101	Shared Neighborhood Hits	54
SwissProt Accessions	P53041, Q16722	Gene names	PPP5C, PPP5
Domain Architecture
Description	Serine/threonine-protein phosphatase 5 (EC 3.1.3.16) (PP5) (Protein phosphatase T) (PP-T) (PPT).

STIP1_HUMAN
θ value	3.41135e-07 (rank : 16)	NC score	0.520212 (rank : 18)
Query Neighborhood Hits	277	Target Neighborhood Hits	147	Shared Neighborhood Hits	60
SwissProt Accessions	P31948	Gene names	STIP1
Domain Architecture
Description	Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (Transformation-sensitive protein IEF SSP 3521) (NY- REN-11 antigen).

SGTA_HUMAN
θ value	7.59969e-07 (rank : 17)	NC score	0.545143 (rank : 13)
Query Neighborhood Hits	277	Target Neighborhood Hits	105	Shared Neighborhood Hits	60
SwissProt Accessions	O43765, Q9BTZ9	Gene names	SGTA, SGT
Domain Architecture
Description	Small glutamine-rich tetratricopeptide repeat-containing protein A (Vpu-binding protein) (UBP).

TTC1_HUMAN
θ value	7.59969e-07 (rank : 18)	NC score	0.527177 (rank : 16)
Query Neighborhood Hits	277	Target Neighborhood Hits	417	Shared Neighborhood Hits	133
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

DNJC7_HUMAN
θ value	4.92598e-06 (rank : 19)	NC score	0.391413 (rank : 26)
Query Neighborhood Hits	277	Target Neighborhood Hits	212	Shared Neighborhood Hits	63
SwissProt Accessions	Q99615	Gene names	DNAJC7, TPR2, TTC2
Domain Architecture
Description	DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2).

PPP5_MOUSE
θ value	4.92598e-06 (rank : 20)	NC score	0.312621 (rank : 33)
Query Neighborhood Hits	277	Target Neighborhood Hits	100	Shared Neighborhood Hits	54
SwissProt Accessions	Q60676, O35299	Gene names	Ppp5c
Domain Architecture
Description	Serine/threonine-protein phosphatase 5 (EC 3.1.3.16) (PP5) (Protein phosphatase T) (PPT).

STUB1_HUMAN
θ value	4.92598e-06 (rank : 21)	NC score	0.528933 (rank : 15)
Query Neighborhood Hits	277	Target Neighborhood Hits	99	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UNE7, O60526, Q969U2, Q9HBT1	Gene names	STUB1, CHIP
Domain Architecture	No domain graphic available
Description	STIP1 homology and U box-containing protein 1 (EC 6.3.2.-) (STIP1 homology and U-box-containing protein 1) (Carboxy terminus of Hsp70- interacting protein) (E3 ubiquitin protein ligase CHIP) (CLL- associated antigen KW-8) (Antigen NY-CO-7).

TTC12_MOUSE
θ value	1.09739e-05 (rank : 22)	NC score	0.474729 (rank : 19)
Query Neighborhood Hits	277	Target Neighborhood Hits	98	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BW49	Gene names	Ttc12
Domain Architecture
Description	Tetratricopeptide repeat protein 12 (TPR repeat protein 12).

DNJC7_MOUSE
θ value	2.44474e-05 (rank : 23)	NC score	0.386982 (rank : 27)
Query Neighborhood Hits	277	Target Neighborhood Hits	211	Shared Neighborhood Hits	63
SwissProt Accessions	Q9QYI3, Q3TKR1, Q8BPG3, Q8CIL2, Q9CT29, Q9D026	Gene names	Dnajc7, Ttc2
Domain Architecture
Description	DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2) (MDj11).

TTC12_HUMAN
θ value	0.000121331 (rank : 24)	NC score	0.468057 (rank : 21)
Query Neighborhood Hits	277	Target Neighborhood Hits	125	Shared Neighborhood Hits	54
SwissProt Accessions	Q9H892, Q8N5H9, Q9NWY3	Gene names	TTC12
Domain Architecture
Description	Tetratricopeptide repeat protein 12 (TPR repeat protein 12).

DYXC1_MOUSE
θ value	0.000158464 (rank : 25)	NC score	0.450739 (rank : 23)
Query Neighborhood Hits	277	Target Neighborhood Hits	172	Shared Neighborhood Hits	58
SwissProt Accessions	Q8R368	Gene names	Dyx1c1, Ekn1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein homolog.

OGT1_HUMAN
θ value	0.00020696 (rank : 26)	NC score	0.339261 (rank : 29)
Query Neighborhood Hits	277	Target Neighborhood Hits	143	Shared Neighborhood Hits	51
SwissProt Accessions	O15294, Q7Z3K0, Q8WWM8, Q96CC1, Q9UG57	Gene names	OGT
Domain Architecture
Description	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.-) (O-GlcNAc transferase p110 subunit).

TTC6_HUMAN
θ value	0.000602161 (rank : 27)	NC score	0.405701 (rank : 25)
Query Neighborhood Hits	277	Target Neighborhood Hits	103	Shared Neighborhood Hits	59
SwissProt Accessions	Q86TZ1, Q96CE6	Gene names	TTC6
Domain Architecture
Description	Tetratricopeptide repeat protein 6 (TPR repeat protein 6).

OM34_HUMAN
θ value	0.00102713 (rank : 28)	NC score	0.468416 (rank : 20)
Query Neighborhood Hits	277	Target Neighborhood Hits	82	Shared Neighborhood Hits	53
SwissProt Accessions	Q15785, Q9NTZ3	Gene names	TOMM34
Domain Architecture
Description	Mitochondrial import receptor subunit TOM34 (Translocase of outer membrane 34 kDa subunit) (hTom34).

DNJC3_HUMAN
θ value	0.00175202 (rank : 29)	NC score	0.285701 (rank : 40)
Query Neighborhood Hits	277	Target Neighborhood Hits	223	Shared Neighborhood Hits	60
SwissProt Accessions	Q13217, Q86WT9, Q8N4N2	Gene names	DNAJC3, P58IPK, PRKRI
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 3 (Interferon-induced, double-stranded RNA-activated protein kinase inhibitor) (Protein kinase inhibitor p58) (Protein kinase inhibitor of 58 kDa).

DNJC3_MOUSE
θ value	0.00175202 (rank : 30)	NC score	0.289804 (rank : 37)
Query Neighborhood Hits	277	Target Neighborhood Hits	230	Shared Neighborhood Hits	65
SwissProt Accessions	Q91YW3, Q60873	Gene names	Dnajc3, P58ipk
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 3 (Interferon-induced, double-stranded RNA-activated protein kinase inhibitor) (Protein kinase inhibitor p58) (Protein kinase inhibitor of 58 kDa).

CDC27_HUMAN
θ value	0.00228821 (rank : 31)	NC score	0.288194 (rank : 39)
Query Neighborhood Hits	277	Target Neighborhood Hits	139	Shared Neighborhood Hits	49
SwissProt Accessions	P30260, Q16349, Q96F35	Gene names	CDC27
Domain Architecture
Description	Cell division cycle protein 27 homolog (CDC27Hs) (H-NUC).

DYXC1_HUMAN
θ value	0.00298849 (rank : 32)	NC score	0.424247 (rank : 24)
Query Neighborhood Hits	277	Target Neighborhood Hits	261	Shared Neighborhood Hits	75
SwissProt Accessions	Q8WXU2, Q6P5Y9	Gene names	DYX1C1, EKN1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein.

OM34_MOUSE
θ value	0.00665767 (rank : 33)	NC score	0.461802 (rank : 22)
Query Neighborhood Hits	277	Target Neighborhood Hits	82	Shared Neighborhood Hits	52
SwissProt Accessions	Q9CYG7, Q3THD0, Q9D059	Gene names	Tomm34
Domain Architecture
Description	Mitochondrial import receptor subunit TOM34 (Translocase of outer membrane 34 kDa subunit).

SUGT1_MOUSE
θ value	0.00869519 (rank : 34)	NC score	0.369444 (rank : 28)
Query Neighborhood Hits	277	Target Neighborhood Hits	73	Shared Neighborhood Hits	48
SwissProt Accessions	Q9CX34, Q3UF88, Q9CRE7, Q9D8M6	Gene names	Sugt1
Domain Architecture
Description	Suppressor of G2 allele of SKP1 homolog.

UN45A_MOUSE
θ value	0.0148317 (rank : 35)	NC score	0.335464 (rank : 30)
Query Neighborhood Hits	277	Target Neighborhood Hits	129	Shared Neighborhood Hits	56
SwissProt Accessions	Q99KD5, Q3TKV6, Q8BFT3, Q8C157	Gene names	Unc45a, Smap1
Domain Architecture	No domain graphic available
Description	UNC45 homolog A (UNC-45A) (Stromal membrane-associated protein 1) (Smap-1).

CDC23_HUMAN
θ value	0.0193708 (rank : 36)	NC score	0.160178 (rank : 64)
Query Neighborhood Hits	277	Target Neighborhood Hits	69	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UJX2, O75433, Q9BS73	Gene names	CDC23
Domain Architecture
Description	Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8).

WDTC1_MOUSE
θ value	0.0193708 (rank : 37)	NC score	0.269923 (rank : 43)
Query Neighborhood Hits	277	Target Neighborhood Hits	298	Shared Neighborhood Hits	44
SwissProt Accessions	Q80ZK9	Gene names	Wdtc1
Domain Architecture
Description	WD and tetratricopeptide repeats protein 1.

NDUS5_HUMAN
θ value	0.0252991 (rank : 38)	NC score	0.215466 (rank : 52)
Query Neighborhood Hits	277	Target Neighborhood Hits	6	Shared Neighborhood Hits	6
SwissProt Accessions	O43920	Gene names	NDUFS5
Domain Architecture	No domain graphic available
Description	NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 (EC 1.6.5.3) (EC 1.6.99.3) (NADH-ubiquinone oxidoreductase 15 kDa subunit) (Complex I-15 kDa) (CI-15 kDa).

RPGR1_MOUSE
θ value	0.0252991 (rank : 39)	NC score	0.099713 (rank : 95)
Query Neighborhood Hits	277	Target Neighborhood Hits	713	Shared Neighborhood Hits	59
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

AP3B1_HUMAN
θ value	0.0330416 (rank : 40)	NC score	0.076747 (rank : 117)
Query Neighborhood Hits	277	Target Neighborhood Hits	283	Shared Neighborhood Hits	28
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

KCC4_MOUSE
θ value	0.0431538 (rank : 41)	NC score	0.006092 (rank : 321)
Query Neighborhood Hits	277	Target Neighborhood Hits	899	Shared Neighborhood Hits	13
SwissProt Accessions	P08414, Q61381	Gene names	Camk4
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type IV (EC 2.7.11.17) (CAM kinase-GR) (CaMK IV).

PELP1_MOUSE
θ value	0.0431538 (rank : 42)	NC score	0.109492 (rank : 87)
Query Neighborhood Hits	277	Target Neighborhood Hits	709	Shared Neighborhood Hits	46
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

SUGT1_HUMAN
θ value	0.0431538 (rank : 43)	NC score	0.303841 (rank : 34)
Query Neighborhood Hits	277	Target Neighborhood Hits	66	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y2Z0, Q5JAK5, Q6VXY6	Gene names	SUGT1
Domain Architecture
Description	Suppressor of G2 allele of SKP1 homolog (Sgt1) (Putative 40-6-3 protein).

AP3B1_MOUSE
θ value	0.0563607 (rank : 44)	NC score	0.073583 (rank : 121)
Query Neighborhood Hits	277	Target Neighborhood Hits	302	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

CD2L1_HUMAN
θ value	0.0736092 (rank : 45)	NC score	0.020029 (rank : 288)
Query Neighborhood Hits	277	Target Neighborhood Hits	1467	Shared Neighborhood Hits	68
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

MYT1_HUMAN
θ value	0.0736092 (rank : 46)	NC score	0.069019 (rank : 132)
Query Neighborhood Hits	277	Target Neighborhood Hits	475	Shared Neighborhood Hits	51
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

PP2CG_HUMAN
θ value	0.0736092 (rank : 47)	NC score	0.081607 (rank : 108)
Query Neighborhood Hits	277	Target Neighborhood Hits	140	Shared Neighborhood Hits	18
SwissProt Accessions	O15355	Gene names	PPM1G, PPM1C
Domain Architecture
Description	Protein phosphatase 2C isoform gamma (EC 3.1.3.16) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C).

RENT2_HUMAN
θ value	0.0736092 (rank : 48)	NC score	0.106278 (rank : 90)
Query Neighborhood Hits	277	Target Neighborhood Hits	618	Shared Neighborhood Hits	58
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

SETD2_HUMAN
θ value	0.0736092 (rank : 49)	NC score	0.066667 (rank : 135)
Query Neighborhood Hits	277	Target Neighborhood Hits	412	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

WDTC1_HUMAN
θ value	0.0736092 (rank : 50)	NC score	0.262399 (rank : 44)
Query Neighborhood Hits	277	Target Neighborhood Hits	299	Shared Neighborhood Hits	45
SwissProt Accessions	Q8N5D0, Q9NV87, Q9UPW4	Gene names	WDTC1, KIAA1037
Domain Architecture
Description	WD and tetratricopeptide repeats protein 1.

NCOR2_HUMAN
θ value	0.0961366 (rank : 51)	NC score	0.085869 (rank : 102)
Query Neighborhood Hits	277	Target Neighborhood Hits	870	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

SMRC2_HUMAN
θ value	0.0961366 (rank : 52)	NC score	0.097609 (rank : 96)
Query Neighborhood Hits	277	Target Neighborhood Hits	499	Shared Neighborhood Hits	68
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

MYO10_HUMAN
θ value	0.125558 (rank : 53)	NC score	0.029658 (rank : 257)
Query Neighborhood Hits	277	Target Neighborhood Hits	920	Shared Neighborhood Hits	66
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

NCOR2_MOUSE
θ value	0.125558 (rank : 54)	NC score	0.085797 (rank : 103)
Query Neighborhood Hits	277	Target Neighborhood Hits	790	Shared Neighborhood Hits	55
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

TNNT3_MOUSE
θ value	0.125558 (rank : 55)	NC score	0.070842 (rank : 128)
Query Neighborhood Hits	277	Target Neighborhood Hits	317	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QZ47, O35575, O35576, O35577, O35578, O35579, O35580, O35581, O35582, O35583, O35584, O35585, P97456, Q99L89, Q9QZ46	Gene names	Tnnt3
Domain Architecture	No domain graphic available
Description	Troponin T, fast skeletal muscle (TnTf) (Fast skeletal muscle troponin T) (fTnT).

TTC16_HUMAN
θ value	0.125558 (rank : 56)	NC score	0.205111 (rank : 54)
Query Neighborhood Hits	277	Target Neighborhood Hits	417	Shared Neighborhood Hits	79
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

UBDC1_HUMAN
θ value	0.125558 (rank : 57)	NC score	0.115523 (rank : 80)
Query Neighborhood Hits	277	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BSL1, O75500, Q9UMW7	Gene names	UBADC1, GBDR1, KPC2
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated domain-containing protein 1 (E3 ubiquitin-protein ligase subunit KPC2) (Kip1 ubiquitination-promoting complex protein 2) (Glialblastoma cell differentiation-related protein 1).

UBDC1_MOUSE
θ value	0.125558 (rank : 58)	NC score	0.115404 (rank : 81)
Query Neighborhood Hits	277	Target Neighborhood Hits	29	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VDI7, Q3TZH3	Gene names	Ubadc1, Kpc2
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated domain-containing protein 1 (E3 ubiquitin-protein ligase subunit KPC2) (Kip1 ubiquitination-promoting complex protein 2).

UBF1_HUMAN
θ value	0.125558 (rank : 59)	NC score	0.088075 (rank : 100)
Query Neighborhood Hits	277	Target Neighborhood Hits	415	Shared Neighborhood Hits	48
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

ANXA7_HUMAN
θ value	0.163984 (rank : 60)	NC score	0.025656 (rank : 270)
Query Neighborhood Hits	277	Target Neighborhood Hits	168	Shared Neighborhood Hits	5
SwissProt Accessions	P20073	Gene names	ANXA7, ANX7, SNX
Domain Architecture
Description	Annexin A7 (Annexin VII) (Synexin).

CAR10_HUMAN
θ value	0.163984 (rank : 61)	NC score	0.041237 (rank : 212)
Query Neighborhood Hits	277	Target Neighborhood Hits	569	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BWT7, Q14CQ8, Q5TFG6, Q9UGR5, Q9UGR6, Q9Y3H0	Gene names	CARD10, CARMA3
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3).

CENPF_HUMAN
θ value	0.163984 (rank : 62)	NC score	0.038635 (rank : 221)
Query Neighborhood Hits	277	Target Neighborhood Hits	1932	Shared Neighborhood Hits	103
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

DYNA_HUMAN
θ value	0.163984 (rank : 63)	NC score	0.045824 (rank : 195)
Query Neighborhood Hits	277	Target Neighborhood Hits	1194	Shared Neighborhood Hits	70
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

PELP1_HUMAN
θ value	0.163984 (rank : 64)	NC score	0.102907 (rank : 92)
Query Neighborhood Hits	277	Target Neighborhood Hits	596	Shared Neighborhood Hits	39
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

PTMA_HUMAN
θ value	0.163984 (rank : 65)	NC score	0.205474 (rank : 53)
Query Neighborhood Hits	277	Target Neighborhood Hits	88	Shared Neighborhood Hits	20
SwissProt Accessions	P06454, Q15249, Q15592	Gene names	PTMA, TMSA
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha-1].

TRI44_HUMAN
θ value	0.163984 (rank : 66)	NC score	0.085322 (rank : 104)
Query Neighborhood Hits	277	Target Neighborhood Hits	393	Shared Neighborhood Hits	30
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

BAZ1A_HUMAN
θ value	0.21417 (rank : 67)	NC score	0.070617 (rank : 130)
Query Neighborhood Hits	277	Target Neighborhood Hits	693	Shared Neighborhood Hits	68
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

HAP28_HUMAN
θ value	0.21417 (rank : 68)	NC score	0.108904 (rank : 88)
Query Neighborhood Hits	277	Target Neighborhood Hits	57	Shared Neighborhood Hits	13
SwissProt Accessions	Q13442, Q92906	Gene names	PDAP1, HASPP28
Domain Architecture	No domain graphic available
Description	28 kDa heat- and acid-stable phosphoprotein (PDGF-associated protein) (PAP) (PDGFA-associated protein 1) (PAP1).

NFL_HUMAN
θ value	0.21417 (rank : 69)	NC score	0.036694 (rank : 229)
Query Neighborhood Hits	277	Target Neighborhood Hits	666	Shared Neighborhood Hits	49
SwissProt Accessions	P07196, Q16154, Q8IU72	Gene names	NEFL, NF68, NFL
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

NSBP1_MOUSE
θ value	0.21417 (rank : 70)	NC score	0.155712 (rank : 66)
Query Neighborhood Hits	277	Target Neighborhood Hits	681	Shared Neighborhood Hits	128
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

NUCL_HUMAN
θ value	0.21417 (rank : 71)	NC score	0.056804 (rank : 153)
Query Neighborhood Hits	277	Target Neighborhood Hits	415	Shared Neighborhood Hits	30
SwissProt Accessions	P19338, Q53SK1, Q8NB06	Gene names	NCL
Domain Architecture
Description	Nucleolin (Protein C23).

PEG3_MOUSE
θ value	0.21417 (rank : 72)	NC score	0.020926 (rank : 285)
Query Neighborhood Hits	277	Target Neighborhood Hits	1101	Shared Neighborhood Hits	87
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

UN45B_HUMAN
θ value	0.21417 (rank : 73)	NC score	0.299773 (rank : 35)
Query Neighborhood Hits	277	Target Neighborhood Hits	97	Shared Neighborhood Hits	47
SwissProt Accessions	Q8IWX7, Q495Q8, Q495Q9	Gene names	UNC45B, CMYA4, UNC45
Domain Architecture	No domain graphic available
Description	UNC45 homolog B (UNC-45B).

ATAD2_MOUSE
θ value	0.279714 (rank : 74)	NC score	0.020283 (rank : 287)
Query Neighborhood Hits	277	Target Neighborhood Hits	167	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CDM1	Gene names	Atad2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

HTF4_MOUSE
θ value	0.279714 (rank : 75)	NC score	0.044671 (rank : 198)
Query Neighborhood Hits	277	Target Neighborhood Hits	153	Shared Neighborhood Hits	7
SwissProt Accessions	Q61286	Gene names	Tcf12, Alf1, Meb
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4) (Class A helix-loop-helix transcription factor ME1).

NCOR1_MOUSE
θ value	0.279714 (rank : 76)	NC score	0.078617 (rank : 113)
Query Neighborhood Hits	277	Target Neighborhood Hits	521	Shared Neighborhood Hits	44
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

SMRC2_MOUSE
θ value	0.279714 (rank : 77)	NC score	0.089792 (rank : 99)
Query Neighborhood Hits	277	Target Neighborhood Hits	487	Shared Neighborhood Hits	68
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

TCF8_HUMAN
θ value	0.279714 (rank : 78)	NC score	0.014144 (rank : 302)
Query Neighborhood Hits	277	Target Neighborhood Hits	1057	Shared Neighborhood Hits	54
SwissProt Accessions	P37275, Q12924, Q13800	Gene names	TCF8, AREB6
Domain Architecture
Description	Transcription factor 8 (NIL-2-A zinc finger protein) (Negative regulator of IL2).

TGON1_MOUSE
θ value	0.279714 (rank : 79)	NC score	0.075713 (rank : 118)
Query Neighborhood Hits	277	Target Neighborhood Hits	243	Shared Neighborhood Hits	33
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

TTC13_HUMAN
θ value	0.279714 (rank : 80)	NC score	0.277317 (rank : 42)
Query Neighborhood Hits	277	Target Neighborhood Hits	117	Shared Neighborhood Hits	57
SwissProt Accessions	Q8NBP0, Q8IVP8, Q8NBI0, Q8ND20	Gene names	TTC13
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 13 (TPR repeat protein 13).

YTDC1_HUMAN
θ value	0.279714 (rank : 81)	NC score	0.105084 (rank : 91)
Query Neighborhood Hits	277	Target Neighborhood Hits	458	Shared Neighborhood Hits	63
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

BAZ2B_HUMAN
θ value	0.365318 (rank : 82)	NC score	0.064916 (rank : 137)
Query Neighborhood Hits	277	Target Neighborhood Hits	803	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

CDC23_MOUSE
θ value	0.365318 (rank : 83)	NC score	0.137061 (rank : 70)
Query Neighborhood Hits	277	Target Neighborhood Hits	65	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BGZ4, Q8C0F1	Gene names	Cdc23
Domain Architecture
Description	Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8).

CENPB_MOUSE
θ value	0.365318 (rank : 84)	NC score	0.085951 (rank : 101)
Query Neighborhood Hits	277	Target Neighborhood Hits	163	Shared Neighborhood Hits	23
SwissProt Accessions	P27790	Gene names	Cenpb, Cenp-b
Domain Architecture
Description	Major centromere autoantigen B (Centromere protein B) (CENP-B).

FKBP5_HUMAN
θ value	0.365318 (rank : 85)	NC score	0.250773 (rank : 45)
Query Neighborhood Hits	277	Target Neighborhood Hits	107	Shared Neighborhood Hits	52
SwissProt Accessions	Q13451	Gene names	FKBP5, AIG6, FKBP51
Domain Architecture
Description	FK506-binding protein 5 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (51 kDa FK506-binding protein) (FKBP- 51) (54 kDa progesterone receptor-associated immunophilin) (FKBP54) (P54) (FF1 antigen) (HSP90-binding immunophilin) (Androgen-regulated protein 6).

IWS1_MOUSE
θ value	0.365318 (rank : 86)	NC score	0.118797 (rank : 79)
Query Neighborhood Hits	277	Target Neighborhood Hits	1258	Shared Neighborhood Hits	155
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PTMA_MOUSE
θ value	0.365318 (rank : 87)	NC score	0.172082 (rank : 58)
Query Neighborhood Hits	277	Target Neighborhood Hits	73	Shared Neighborhood Hits	16
SwissProt Accessions	P26350, Q3UQV6	Gene names	Ptma
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha].

RPGR_MOUSE
θ value	0.365318 (rank : 88)	NC score	0.061717 (rank : 141)
Query Neighborhood Hits	277	Target Neighborhood Hits	281	Shared Neighborhood Hits	72
SwissProt Accessions	Q9R0X5, O88408, Q9CU92	Gene names	Rpgr
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator (mRpgr).

ADNP_MOUSE
θ value	0.47712 (rank : 89)	NC score	0.061879 (rank : 140)
Query Neighborhood Hits	277	Target Neighborhood Hits	232	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z103	Gene names	Adnp
Domain Architecture
Description	Activity-dependent neuroprotector (Activity-dependent neuroprotective protein).

CALR_MOUSE
θ value	0.47712 (rank : 90)	NC score	0.054080 (rank : 168)
Query Neighborhood Hits	277	Target Neighborhood Hits	68	Shared Neighborhood Hits	12
SwissProt Accessions	P14211	Gene names	Calr
Domain Architecture
Description	Calreticulin precursor (CRP55) (Calregulin) (HACBP) (ERp60).

DAXX_HUMAN
θ value	0.47712 (rank : 91)	NC score	0.079290 (rank : 112)
Query Neighborhood Hits	277	Target Neighborhood Hits	207	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UER7, O14747, O15141, O15208, Q9BWI3	Gene names	DAXX, BING2, DAP6
Domain Architecture
Description	Death domain-associated protein 6 (Daxx) (hDaxx) (Fas death domain- associated protein) (ETS1-associated protein 1) (EAP1).

NASP_HUMAN
θ value	0.47712 (rank : 92)	NC score	0.145501 (rank : 68)
Query Neighborhood Hits	277	Target Neighborhood Hits	709	Shared Neighborhood Hits	125
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

NFL_MOUSE
θ value	0.47712 (rank : 93)	NC score	0.033165 (rank : 242)
Query Neighborhood Hits	277	Target Neighborhood Hits	695	Shared Neighborhood Hits	46
SwissProt Accessions	P08551, Q8K0Z0	Gene names	Nefl, Nf68, Nfl
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

RRMJ3_MOUSE
θ value	0.47712 (rank : 94)	NC score	0.054312 (rank : 166)
Query Neighborhood Hits	277	Target Neighborhood Hits	163	Shared Neighborhood Hits	14
SwissProt Accessions	Q9DBE9, Q3ULI1, Q921I7	Gene names	Ftsj3
Domain Architecture	No domain graphic available
Description	Putative rRNA methyltransferase 3 (EC 2.1.1.-) (rRNA (uridine-2'-O-)- methyltransferase 3).

SFR12_MOUSE
θ value	0.47712 (rank : 95)	NC score	0.071864 (rank : 125)
Query Neighborhood Hits	277	Target Neighborhood Hits	486	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

UBF1_MOUSE
θ value	0.47712 (rank : 96)	NC score	0.082774 (rank : 107)
Query Neighborhood Hits	277	Target Neighborhood Hits	419	Shared Neighborhood Hits	45
SwissProt Accessions	P25976	Gene names	Ubtf, Tcfubf, Ubf-1, Ubf1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1).

CRNL1_HUMAN
θ value	0.62314 (rank : 97)	NC score	0.052794 (rank : 173)
Query Neighborhood Hits	277	Target Neighborhood Hits	76	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BZJ0, Q5JY64, Q8WYI5, Q9BZI9, Q9BZJ1, Q9BZJ2, Q9GZW7, Q9H8F8, Q9NQH5, Q9NYD8	Gene names	CRNKL1, CRN
Domain Architecture
Description	Crooked neck-like protein 1 (Crooked neck homolog) (hCrn).

FKBP4_HUMAN
θ value	0.62314 (rank : 98)	NC score	0.248508 (rank : 46)
Query Neighborhood Hits	277	Target Neighborhood Hits	114	Shared Neighborhood Hits	56
SwissProt Accessions	Q02790, Q9UCP1, Q9UCV7	Gene names	FKBP4
Domain Architecture
Description	FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (p59 protein) (HSP-binding immunophilin) (HBI) (FKBP52 protein) (52 kDa FK506-binding protein) (FKBP59).

GLU2B_MOUSE
θ value	0.62314 (rank : 99)	NC score	0.048104 (rank : 189)
Query Neighborhood Hits	277	Target Neighborhood Hits	357	Shared Neighborhood Hits	31
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

HUWE1_HUMAN
θ value	0.62314 (rank : 100)	NC score	0.036587 (rank : 231)
Query Neighborhood Hits	277	Target Neighborhood Hits	443	Shared Neighborhood Hits	28
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

HUWE1_MOUSE
θ value	0.62314 (rank : 101)	NC score	0.035435 (rank : 234)
Query Neighborhood Hits	277	Target Neighborhood Hits	406	Shared Neighborhood Hits	24
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

UN45B_MOUSE
θ value	0.62314 (rank : 102)	NC score	0.296659 (rank : 36)
Query Neighborhood Hits	277	Target Neighborhood Hits	90	Shared Neighborhood Hits	46
SwissProt Accessions	Q8CGY6, Q5XG72, Q8BHC5, Q8BWK3	Gene names	Unc45b, Cmya4
Domain Architecture	No domain graphic available
Description	UNC45 homolog B (UNC-45B).

APLP2_HUMAN
θ value	0.813845 (rank : 103)	NC score	0.034245 (rank : 236)
Query Neighborhood Hits	277	Target Neighborhood Hits	193	Shared Neighborhood Hits	17
SwissProt Accessions	Q06481	Gene names	APLP2, APPL2
Domain Architecture
Description	Amyloid-like protein 2 precursor (Amyloid protein homolog) (APPH) (CDEI box-binding protein) (CDEBP).

ATRX_MOUSE
θ value	0.813845 (rank : 104)	NC score	0.056734 (rank : 154)
Query Neighborhood Hits	277	Target Neighborhood Hits	682	Shared Neighborhood Hits	68
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

BBS4_MOUSE
θ value	0.813845 (rank : 105)	NC score	0.200055 (rank : 56)
Query Neighborhood Hits	277	Target Neighborhood Hits	95	Shared Neighborhood Hits	50
SwissProt Accessions	Q8C1Z7, Q3UYF0, Q8CA57	Gene names	Bbs4
Domain Architecture
Description	Bardet-Biedl syndrome 4 protein homolog.

CBP_MOUSE
θ value	0.813845 (rank : 106)	NC score	0.042069 (rank : 209)
Query Neighborhood Hits	277	Target Neighborhood Hits	1051	Shared Neighborhood Hits	40
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CD2L1_MOUSE
θ value	0.813845 (rank : 107)	NC score	0.017720 (rank : 291)
Query Neighborhood Hits	277	Target Neighborhood Hits	1463	Shared Neighborhood Hits	73
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

CHD4_HUMAN
θ value	0.813845 (rank : 108)	NC score	0.030861 (rank : 251)
Query Neighborhood Hits	277	Target Neighborhood Hits	365	Shared Neighborhood Hits	33
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

FGL2_HUMAN
θ value	0.813845 (rank : 109)	NC score	0.021193 (rank : 283)
Query Neighborhood Hits	277	Target Neighborhood Hits	101	Shared Neighborhood Hits	8
SwissProt Accessions	Q14314	Gene names	FGL2
Domain Architecture
Description	Fibroleukin precursor (Fibrinogen-like protein 2) (pT49).

HTF4_HUMAN
θ value	0.813845 (rank : 110)	NC score	0.043869 (rank : 204)
Query Neighborhood Hits	277	Target Neighborhood Hits	152	Shared Neighborhood Hits	8
SwissProt Accessions	Q99081	Gene names	TCF12, HEB, HTF4
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4).

MS3L1_HUMAN
θ value	0.813845 (rank : 111)	NC score	0.047044 (rank : 194)
Query Neighborhood Hits	277	Target Neighborhood Hits	60	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N5Y2, Q9UG70, Q9Y5Z8	Gene names	MSL3L1
Domain Architecture
Description	Male-specific lethal 3-like 1 (MSL3-like 1) (Male-specific lethal-3 homolog 1).

NFH_MOUSE
θ value	0.813845 (rank : 112)	NC score	0.044632 (rank : 200)
Query Neighborhood Hits	277	Target Neighborhood Hits	2247	Shared Neighborhood Hits	118
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

NFM_MOUSE
θ value	0.813845 (rank : 113)	NC score	0.040558 (rank : 215)
Query Neighborhood Hits	277	Target Neighborhood Hits	1159	Shared Neighborhood Hits	90
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

PEX5_HUMAN
θ value	0.813845 (rank : 114)	NC score	0.159439 (rank : 65)
Query Neighborhood Hits	277	Target Neighborhood Hits	92	Shared Neighborhood Hits	36
SwissProt Accessions	P50542, Q15115, Q15266	Gene names	PEX5, PXR1
Domain Architecture
Description	Peroxisomal targeting signal 1 receptor (Peroxisome receptor 1) (Peroxisomal C-terminal targeting signal import receptor) (PTS1-BP) (Peroxin-5) (PTS1 receptor).

RP1L1_HUMAN
θ value	0.813845 (rank : 115)	NC score	0.054040 (rank : 169)
Query Neighborhood Hits	277	Target Neighborhood Hits	1072	Shared Neighborhood Hits	72
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

TCAL3_MOUSE
θ value	0.813845 (rank : 116)	NC score	0.055424 (rank : 161)
Query Neighborhood Hits	277	Target Neighborhood Hits	132	Shared Neighborhood Hits	28
SwissProt Accessions	Q8R0A5, Q9CYK5, Q9D1S4	Gene names	Tceal3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

UN45A_HUMAN
θ value	0.813845 (rank : 117)	NC score	0.289518 (rank : 38)
Query Neighborhood Hits	277	Target Neighborhood Hits	122	Shared Neighborhood Hits	50
SwissProt Accessions	Q9H3U1, Q7L3Y6, Q9H3U8, Q9NSE8, Q9NSE9	Gene names	UNC45A, SMAP1
Domain Architecture	No domain graphic available
Description	UNC45 homolog A (UNC-45A) (Smooth muscle cell-associated protein 1) (SMAP-1).

CALR_HUMAN
θ value	1.06291 (rank : 118)	NC score	0.047407 (rank : 193)
Query Neighborhood Hits	277	Target Neighborhood Hits	85	Shared Neighborhood Hits	15
SwissProt Accessions	P27797	Gene names	CALR, CRTC
Domain Architecture
Description	Calreticulin precursor (CRP55) (Calregulin) (HACBP) (ERp60) (grp60).

CD2L2_HUMAN
θ value	1.06291 (rank : 119)	NC score	0.015894 (rank : 293)
Query Neighborhood Hits	277	Target Neighborhood Hits	1439	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

CHD6_HUMAN
θ value	1.06291 (rank : 120)	NC score	0.032075 (rank : 245)
Query Neighborhood Hits	277	Target Neighborhood Hits	342	Shared Neighborhood Hits	39
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

DDX49_HUMAN
θ value	1.06291 (rank : 121)	NC score	0.011841 (rank : 309)
Query Neighborhood Hits	277	Target Neighborhood Hits	223	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

FKBP4_MOUSE
θ value	1.06291 (rank : 122)	NC score	0.232969 (rank : 49)
Query Neighborhood Hits	277	Target Neighborhood Hits	100	Shared Neighborhood Hits	49
SwissProt Accessions	P30416, Q3TVC9	Gene names	Fkbp4
Domain Architecture
Description	FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (p59 protein) (HSP-binding immunophilin) (HBI) (FKBP52 protein) (52 kDa FK506-binding protein) (FKBP59).

FKBP5_MOUSE
θ value	1.06291 (rank : 123)	NC score	0.241020 (rank : 48)
Query Neighborhood Hits	277	Target Neighborhood Hits	97	Shared Neighborhood Hits	50
SwissProt Accessions	Q64378	Gene names	Fkbp5, Fkbp51
Domain Architecture
Description	FK506-binding protein 5 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (51 kDa FK506-binding protein) (FKBP- 51).

HDAC1_HUMAN
θ value	1.06291 (rank : 124)	NC score	0.030218 (rank : 253)
Query Neighborhood Hits	277	Target Neighborhood Hits	49	Shared Neighborhood Hits	12
SwissProt Accessions	Q13547, Q92534	Gene names	HDAC1, RPD3L1
Domain Architecture
Description	Histone deacetylase 1 (HD1).

HDAC1_MOUSE
θ value	1.06291 (rank : 125)	NC score	0.030067 (rank : 254)
Query Neighborhood Hits	277	Target Neighborhood Hits	46	Shared Neighborhood Hits	12
SwissProt Accessions	O09106, P97476	Gene names	Hdac1
Domain Architecture
Description	Histone deacetylase 1 (HD1).

HS90A_MOUSE
θ value	1.06291 (rank : 126)	NC score	0.038122 (rank : 223)
Query Neighborhood Hits	277	Target Neighborhood Hits	155	Shared Neighborhood Hits	21
SwissProt Accessions	P07901	Gene names	Hsp90aa1, Hsp86, Hsp86-1, Hspca
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (Tumor-specific transplantation 86 kDa antigen) (TSTA).

LEO1_HUMAN
θ value	1.06291 (rank : 127)	NC score	0.132120 (rank : 74)
Query Neighborhood Hits	277	Target Neighborhood Hits	958	Shared Neighborhood Hits	146
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

NDUS5_MOUSE
θ value	1.06291 (rank : 128)	NC score	0.118901 (rank : 78)
Query Neighborhood Hits	277	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	Q99LY9	Gene names	Ndufs5
Domain Architecture	No domain graphic available
Description	NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 (EC 1.6.5.3) (EC 1.6.99.3) (NADH-ubiquinone oxidoreductase 15 kDa subunit) (Complex I-15 kDa) (CI-15 kDa).

NRDC_MOUSE
θ value	1.06291 (rank : 129)	NC score	0.043131 (rank : 206)
Query Neighborhood Hits	277	Target Neighborhood Hits	96	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BHG1	Gene names	Nrd1
Domain Architecture
Description	Nardilysin precursor (EC 3.4.24.61) (N-arginine dibasic convertase) (NRD convertase) (NRD-C).

NUCL_MOUSE
θ value	1.06291 (rank : 130)	NC score	0.048286 (rank : 188)
Query Neighborhood Hits	277	Target Neighborhood Hits	425	Shared Neighborhood Hits	29
SwissProt Accessions	P09405, Q548M9, Q61991, Q99K50	Gene names	Ncl, Nuc
Domain Architecture
Description	Nucleolin (Protein C23).

SLK_HUMAN
θ value	1.06291 (rank : 131)	NC score	0.009449 (rank : 314)
Query Neighborhood Hits	277	Target Neighborhood Hits	1775	Shared Neighborhood Hits	82
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

TRI44_MOUSE
θ value	1.06291 (rank : 132)	NC score	0.072521 (rank : 122)
Query Neighborhood Hits	277	Target Neighborhood Hits	327	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

TTC4_HUMAN
θ value	1.06291 (rank : 133)	NC score	0.313089 (rank : 32)
Query Neighborhood Hits	277	Target Neighborhood Hits	75	Shared Neighborhood Hits	46
SwissProt Accessions	O95801, Q9H3I2	Gene names	TTC4
Domain Architecture
Description	Tetratricopeptide repeat protein 4 (TPR repeat protein 4).

ZN622_HUMAN
θ value	1.06291 (rank : 134)	NC score	0.058562 (rank : 147)
Query Neighborhood Hits	277	Target Neighborhood Hits	62	Shared Neighborhood Hits	9
SwissProt Accessions	Q969S3	Gene names	ZNF622, ZPR9
Domain Architecture	No domain graphic available
Description	Zinc finger protein 622 (Zinc finger-like protein 9).

AN32B_MOUSE
θ value	1.38821 (rank : 135)	NC score	0.048637 (rank : 187)
Query Neighborhood Hits	277	Target Neighborhood Hits	236	Shared Neighborhood Hits	23
SwissProt Accessions	Q9EST5	Gene names	Anp32b, Pal31
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member B (Proliferation-related acidic leucine-rich protein PAL31).

CYLC1_HUMAN
θ value	1.38821 (rank : 136)	NC score	0.072496 (rank : 123)
Query Neighborhood Hits	277	Target Neighborhood Hits	408	Shared Neighborhood Hits	45
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

GSDM1_HUMAN
θ value	1.38821 (rank : 137)	NC score	0.036958 (rank : 228)
Query Neighborhood Hits	277	Target Neighborhood Hits	32	Shared Neighborhood Hits	6
SwissProt Accessions	Q96QA5, Q8N1M6	Gene names	GSDM1, GSDM
Domain Architecture	No domain graphic available
Description	Gasdermin.

KI21A_HUMAN
θ value	1.38821 (rank : 138)	NC score	0.041043 (rank : 214)
Query Neighborhood Hits	277	Target Neighborhood Hits	1543	Shared Neighborhood Hits	98
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

MDN1_HUMAN
θ value	1.38821 (rank : 139)	NC score	0.090353 (rank : 98)
Query Neighborhood Hits	277	Target Neighborhood Hits	662	Shared Neighborhood Hits	106
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

NP1L3_MOUSE
θ value	1.38821 (rank : 140)	NC score	0.044195 (rank : 203)
Query Neighborhood Hits	277	Target Neighborhood Hits	233	Shared Neighborhood Hits	35
SwissProt Accessions	Q794H2, O54802	Gene names	Nap1l3, Mb20
Domain Architecture	No domain graphic available
Description	Nucleosome assembly protein 1-like 3 (Brain-specific protein MB20).

PEX5R_HUMAN
θ value	1.38821 (rank : 141)	NC score	0.133804 (rank : 73)
Query Neighborhood Hits	277	Target Neighborhood Hits	102	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IYB4, Q9NQD1, Q9P2U3, Q9P2U4	Gene names	PEX5L, PEX5R, PXR2
Domain Architecture
Description	PEX5-related protein (Peroxin-5-related protein) (Pex5Rp) (PEX5-like protein) (PEX2-related protein).

PEX5R_MOUSE
θ value	1.38821 (rank : 142)	NC score	0.135121 (rank : 71)
Query Neighborhood Hits	277	Target Neighborhood Hits	80	Shared Neighborhood Hits	31
SwissProt Accessions	Q8C437, Q8CA31, Q9DAA1, Q9JMB9	Gene names	Pex5l, Pex2, Pex5r, Pxr2
Domain Architecture
Description	PEX5-related protein (Peroxin-5-related protein) (Pex5Rp) (PEX5-like protein) (PEX2-related protein).

PEX5_MOUSE
θ value	1.38821 (rank : 143)	NC score	0.161264 (rank : 62)
Query Neighborhood Hits	277	Target Neighborhood Hits	89	Shared Neighborhood Hits	39
SwissProt Accessions	O09012	Gene names	Pex5, Pxr1
Domain Architecture
Description	Peroxisomal targeting signal 1 receptor (Peroxisome receptor 1) (Peroxisomal C-terminal targeting signal import receptor) (PTS1-BP) (Peroxin-5) (PTS1 receptor) (PXR1P) (PTS1R).

SMC4_HUMAN
θ value	1.38821 (rank : 144)	NC score	0.028286 (rank : 261)
Query Neighborhood Hits	277	Target Neighborhood Hits	937	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

SPRL1_MOUSE
θ value	1.38821 (rank : 145)	NC score	0.077407 (rank : 115)
Query Neighborhood Hits	277	Target Neighborhood Hits	403	Shared Neighborhood Hits	86
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

ABTAP_MOUSE
θ value	1.81305 (rank : 146)	NC score	0.055846 (rank : 158)
Query Neighborhood Hits	277	Target Neighborhood Hits	381	Shared Neighborhood Hits	37
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

ATRX_HUMAN
θ value	1.81305 (rank : 147)	NC score	0.060894 (rank : 142)
Query Neighborhood Hits	277	Target Neighborhood Hits	842	Shared Neighborhood Hits	90
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

BBS4_HUMAN
θ value	1.81305 (rank : 148)	NC score	0.193278 (rank : 57)
Query Neighborhood Hits	277	Target Neighborhood Hits	109	Shared Neighborhood Hits	52
SwissProt Accessions	Q96RK4, Q8NHU9, Q96H45	Gene names	BBS4
Domain Architecture
Description	Bardet-Biedl syndrome 4 protein.

CBP_HUMAN
θ value	1.81305 (rank : 149)	NC score	0.041191 (rank : 213)
Query Neighborhood Hits	277	Target Neighborhood Hits	941	Shared Neighborhood Hits	37
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CDC37_HUMAN
θ value	1.81305 (rank : 150)	NC score	0.063937 (rank : 138)
Query Neighborhood Hits	277	Target Neighborhood Hits	506	Shared Neighborhood Hits	58
SwissProt Accessions	Q16543	Gene names	CDC37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

DDX27_HUMAN
θ value	1.81305 (rank : 151)	NC score	0.014598 (rank : 300)
Query Neighborhood Hits	277	Target Neighborhood Hits	197	Shared Neighborhood Hits	20
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

FA44A_HUMAN
θ value	1.81305 (rank : 152)	NC score	0.043618 (rank : 205)
Query Neighborhood Hits	277	Target Neighborhood Hits	280	Shared Neighborhood Hits	39
SwissProt Accessions	Q8NFC6, Q6P0M8	Gene names	FAM44A
Domain Architecture	No domain graphic available
Description	Protein FAM44A.

HAP1_HUMAN
θ value	1.81305 (rank : 153)	NC score	0.025313 (rank : 271)
Query Neighborhood Hits	277	Target Neighborhood Hits	606	Shared Neighborhood Hits	31
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

IFIT2_MOUSE
θ value	1.81305 (rank : 154)	NC score	0.036989 (rank : 227)
Query Neighborhood Hits	277	Target Neighborhood Hits	32	Shared Neighborhood Hits	15
SwissProt Accessions	Q64112, Q62385	Gene names	Ifit2, Garg39, Ifi54
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 2 (IFIT-2) (Interferon-induced 54 kDa protein) (IFI-54K) (Glucocorticoid- attenuated response gene 39 protein) (GARG-39).

KI21A_MOUSE
θ value	1.81305 (rank : 155)	NC score	0.037139 (rank : 226)
Query Neighborhood Hits	277	Target Neighborhood Hits	1317	Shared Neighborhood Hits	79
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

MYO5A_MOUSE
θ value	1.81305 (rank : 156)	NC score	0.022996 (rank : 280)
Query Neighborhood Hits	277	Target Neighborhood Hits	1117	Shared Neighborhood Hits	76
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

MYST4_HUMAN
θ value	1.81305 (rank : 157)	NC score	0.055190 (rank : 162)
Query Neighborhood Hits	277	Target Neighborhood Hits	671	Shared Neighborhood Hits	85
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

NFH_HUMAN
θ value	1.81305 (rank : 158)	NC score	0.039992 (rank : 217)
Query Neighborhood Hits	277	Target Neighborhood Hits	1242	Shared Neighborhood Hits	80
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PP2CG_MOUSE
θ value	1.81305 (rank : 159)	NC score	0.055182 (rank : 163)
Query Neighborhood Hits	277	Target Neighborhood Hits	185	Shared Neighborhood Hits	16
SwissProt Accessions	Q61074	Gene names	Ppm1g, Fin13, Ppm1c
Domain Architecture
Description	Protein phosphatase 2C isoform gamma (EC 3.1.3.16) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C) (Fibroblast growth factor-inducible protein 13) (FIN13).

TTC16_MOUSE
θ value	1.81305 (rank : 160)	NC score	0.226131 (rank : 50)
Query Neighborhood Hits	277	Target Neighborhood Hits	98	Shared Neighborhood Hits	49
SwissProt Accessions	Q8C1F5	Gene names	Ttc16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

ABCF1_HUMAN
θ value	2.36792 (rank : 161)	NC score	0.035254 (rank : 235)
Query Neighborhood Hits	277	Target Neighborhood Hits	343	Shared Neighborhood Hits	33
SwissProt Accessions	Q8NE71, O14897, Q69YP6	Gene names	ABCF1, ABC50
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein).

BAZ1B_HUMAN
θ value	2.36792 (rank : 162)	NC score	0.052709 (rank : 174)
Query Neighborhood Hits	277	Target Neighborhood Hits	701	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

CENPB_HUMAN
θ value	2.36792 (rank : 163)	NC score	0.074950 (rank : 119)
Query Neighborhood Hits	277	Target Neighborhood Hits	133	Shared Neighborhood Hits	22
SwissProt Accessions	P07199	Gene names	CENPB
Domain Architecture
Description	Major centromere autoantigen B (Centromere protein B) (CENP-B).

CLSPN_HUMAN
θ value	2.36792 (rank : 164)	NC score	0.051734 (rank : 178)
Query Neighborhood Hits	277	Target Neighborhood Hits	433	Shared Neighborhood Hits	51
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

CP053_HUMAN
θ value	2.36792 (rank : 165)	NC score	0.070637 (rank : 129)
Query Neighborhood Hits	277	Target Neighborhood Hits	45	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BTK6	Gene names	C16orf53
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf53.

CTTB2_HUMAN
θ value	2.36792 (rank : 166)	NC score	0.021417 (rank : 282)
Query Neighborhood Hits	277	Target Neighborhood Hits	1061	Shared Neighborhood Hits	44
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

CYLN2_MOUSE
θ value	2.36792 (rank : 167)	NC score	0.024084 (rank : 276)
Query Neighborhood Hits	277	Target Neighborhood Hits	1002	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

DNJC8_HUMAN
θ value	2.36792 (rank : 168)	NC score	0.069947 (rank : 131)
Query Neighborhood Hits	277	Target Neighborhood Hits	380	Shared Neighborhood Hits	50
SwissProt Accessions	O75937, Q6IBA4, Q8N4Z5, Q9P051, Q9P067	Gene names	DNAJC8, SPF31
Domain Architecture
Description	DnaJ homolog subfamily C member 8 (Splicing protein spf31).

DNJC8_MOUSE
θ value	2.36792 (rank : 169)	NC score	0.071335 (rank : 127)
Query Neighborhood Hits	277	Target Neighborhood Hits	392	Shared Neighborhood Hits	53
SwissProt Accessions	Q6NZB0, Q6PG72, Q8C2M6	Gene names	Dnajc8
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 8.

GMIP_HUMAN
θ value	2.36792 (rank : 170)	NC score	0.010289 (rank : 312)
Query Neighborhood Hits	277	Target Neighborhood Hits	225	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

HNRCL_HUMAN
θ value	2.36792 (rank : 171)	NC score	0.035486 (rank : 233)
Query Neighborhood Hits	277	Target Neighborhood Hits	232	Shared Neighborhood Hits	10
SwissProt Accessions	O60812	Gene names	HNRPCL1
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein C-like 1 (hnRNP core protein C-like 1).

HTSF1_MOUSE
θ value	2.36792 (rank : 172)	NC score	0.066922 (rank : 134)
Query Neighborhood Hits	277	Target Neighborhood Hits	425	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

MAP2_MOUSE
θ value	2.36792 (rank : 173)	NC score	0.036635 (rank : 230)
Query Neighborhood Hits	277	Target Neighborhood Hits	342	Shared Neighborhood Hits	47
SwissProt Accessions	P20357	Gene names	Map2, Mtap2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2).

MYT1L_MOUSE
θ value	2.36792 (rank : 174)	NC score	0.045767 (rank : 196)
Query Neighborhood Hits	277	Target Neighborhood Hits	461	Shared Neighborhood Hits	43
SwissProt Accessions	P97500, O08996, Q8C643, Q8C7L4, Q8CHB4	Gene names	Myt1l, Kiaa1106, Nzf1, Png1
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (Postmitotic neural gene 1 protein) (Zinc finger protein Png-1) (Neural zinc finger factor 1) (NZF-1).

PCLO_HUMAN
θ value	2.36792 (rank : 175)	NC score	0.027865 (rank : 263)
Query Neighborhood Hits	277	Target Neighborhood Hits	2046	Shared Neighborhood Hits	90
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PTMS_MOUSE
θ value	2.36792 (rank : 176)	NC score	0.148494 (rank : 67)
Query Neighborhood Hits	277	Target Neighborhood Hits	68	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D0J8	Gene names	Ptms
Domain Architecture	No domain graphic available
Description	Parathymosin.

RBBP5_HUMAN
θ value	2.36792 (rank : 177)	NC score	0.041714 (rank : 211)
Query Neighborhood Hits	277	Target Neighborhood Hits	372	Shared Neighborhood Hits	54
SwissProt Accessions	Q15291	Gene names	RBBP5, RBQ3
Domain Architecture
Description	Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3).

SMC4_MOUSE
θ value	2.36792 (rank : 178)	NC score	0.027521 (rank : 264)
Query Neighborhood Hits	277	Target Neighborhood Hits	830	Shared Neighborhood Hits	43
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

TBC16_HUMAN
θ value	2.36792 (rank : 179)	NC score	0.029827 (rank : 256)
Query Neighborhood Hits	277	Target Neighborhood Hits	55	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TBP0	Gene names	TBC1D16
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 16.

TGON2_MOUSE
θ value	2.36792 (rank : 180)	NC score	0.057866 (rank : 150)
Query Neighborhood Hits	277	Target Neighborhood Hits	277	Shared Neighborhood Hits	36
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

ANR18_HUMAN
θ value	3.0926 (rank : 181)	NC score	0.015485 (rank : 296)
Query Neighborhood Hits	277	Target Neighborhood Hits	1106	Shared Neighborhood Hits	54
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

BRD2_HUMAN
θ value	3.0926 (rank : 182)	NC score	0.033916 (rank : 237)
Query Neighborhood Hits	277	Target Neighborhood Hits	242	Shared Neighborhood Hits	23
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

CCDC3_HUMAN
θ value	3.0926 (rank : 183)	NC score	0.044681 (rank : 197)
Query Neighborhood Hits	277	Target Neighborhood Hits	111	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BQI4	Gene names	CCDC3
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 3 precursor.

CXA8_HUMAN
θ value	3.0926 (rank : 184)	NC score	0.009892 (rank : 313)
Query Neighborhood Hits	277	Target Neighborhood Hits	65	Shared Neighborhood Hits	3
SwissProt Accessions	P48165, Q9NP25	Gene names	GJA8
Domain Architecture
Description	Gap junction alpha-8 protein (Connexin-50) (Cx50) (Lens fiber protein MP70).

DAXX_MOUSE
θ value	3.0926 (rank : 185)	NC score	0.066607 (rank : 136)
Query Neighborhood Hits	277	Target Neighborhood Hits	173	Shared Neighborhood Hits	20
SwissProt Accessions	O35613, Q9QWT8, Q9QWV3	Gene names	Daxx
Domain Architecture
Description	Death domain-associated protein 6 (Daxx).

DDX21_MOUSE
θ value	3.0926 (rank : 186)	NC score	0.026357 (rank : 267)
Query Neighborhood Hits	277	Target Neighborhood Hits	350	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

HXC10_MOUSE
θ value	3.0926 (rank : 187)	NC score	0.009346 (rank : 315)
Query Neighborhood Hits	277	Target Neighborhood Hits	417	Shared Neighborhood Hits	20
SwissProt Accessions	P31257, P31312, Q7TMT7	Gene names	Hoxc10, Hox-3.6, Hoxc-10
Domain Architecture	No domain graphic available
Description	Homeobox protein Hox-C10 (Hox-3.6).

LRCH2_MOUSE
θ value	3.0926 (rank : 188)	NC score	0.008323 (rank : 317)
Query Neighborhood Hits	277	Target Neighborhood Hits	287	Shared Neighborhood Hits	8
SwissProt Accessions	Q3UMG5, Q7TNP9, Q80TC9	Gene names	Lrch2, Kiaa1495
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 2.

MYPT2_HUMAN
θ value	3.0926 (rank : 189)	NC score	0.020933 (rank : 284)
Query Neighborhood Hits	277	Target Neighborhood Hits	707	Shared Neighborhood Hits	39
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

RYR1_HUMAN
θ value	3.0926 (rank : 190)	NC score	0.028982 (rank : 259)
Query Neighborhood Hits	277	Target Neighborhood Hits	303	Shared Neighborhood Hits	28
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

SF3B2_HUMAN
θ value	3.0926 (rank : 191)	NC score	0.037988 (rank : 224)
Query Neighborhood Hits	277	Target Neighborhood Hits	157	Shared Neighborhood Hits	18
SwissProt Accessions	Q13435	Gene names	SF3B2, SAP145
Domain Architecture
Description	Splicing factor 3B subunit 2 (Spliceosome-associated protein 145) (SAP 145) (SF3b150) (Pre-mRNA-splicing factor SF3b 145 kDa subunit).

TTBK1_HUMAN
θ value	3.0926 (rank : 192)	NC score	0.012482 (rank : 308)
Query Neighborhood Hits	277	Target Neighborhood Hits	1058	Shared Neighborhood Hits	33
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

ZCHC9_HUMAN
θ value	3.0926 (rank : 193)	NC score	0.029857 (rank : 255)
Query Neighborhood Hits	277	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N567, Q9H027	Gene names	ZCCHC9
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 9.

AATF_MOUSE
θ value	4.03905 (rank : 194)	NC score	0.035892 (rank : 232)
Query Neighborhood Hits	277	Target Neighborhood Hits	50	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JKX4, Q7TQN1, Q8C5Q2, Q99P89	Gene names	Aatf, Che1, Trb
Domain Architecture	No domain graphic available
Description	Protein AATF (Apoptosis-antagonizing transcription factor) (Rb-binding protein Che-1) (Traube protein).

AKAP9_HUMAN
θ value	4.03905 (rank : 195)	NC score	0.026487 (rank : 266)
Query Neighborhood Hits	277	Target Neighborhood Hits	1710	Shared Neighborhood Hits	92
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

AR13B_HUMAN
θ value	4.03905 (rank : 196)	NC score	0.032122 (rank : 244)
Query Neighborhood Hits	277	Target Neighborhood Hits	528	Shared Neighborhood Hits	64
SwissProt Accessions	Q3SXY8, Q504W8	Gene names	ARL13B, ARL2L1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 2-like 1) (ARL2-like protein 1).

CHD2_HUMAN
θ value	4.03905 (rank : 197)	NC score	0.031267 (rank : 249)
Query Neighborhood Hits	277	Target Neighborhood Hits	360	Shared Neighborhood Hits	30
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

CI093_HUMAN
θ value	4.03905 (rank : 198)	NC score	0.031584 (rank : 246)
Query Neighborhood Hits	277	Target Neighborhood Hits	1088	Shared Neighborhood Hits	72
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

CTF1_MOUSE
θ value	4.03905 (rank : 199)	NC score	0.020286 (rank : 286)
Query Neighborhood Hits	277	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q60753	Gene names	Ctf1
Domain Architecture	No domain graphic available
Description	Cardiotrophin-1 (CT-1).

DMD_HUMAN
θ value	4.03905 (rank : 200)	NC score	0.024794 (rank : 273)
Query Neighborhood Hits	277	Target Neighborhood Hits	1135	Shared Neighborhood Hits	69
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

FKBP8_MOUSE
θ value	4.03905 (rank : 201)	NC score	0.242573 (rank : 47)
Query Neighborhood Hits	277	Target Neighborhood Hits	94	Shared Neighborhood Hits	51
SwissProt Accessions	O35465, Q99L93	Gene names	Fkbp8, Fkbp38, Sam11
Domain Architecture
Description	38 kDa FK506-binding protein homolog (FKBPR38) (FK506-binding protein 8) (muFKBP38).

HAP28_MOUSE
θ value	4.03905 (rank : 202)	NC score	0.063652 (rank : 139)
Query Neighborhood Hits	277	Target Neighborhood Hits	50	Shared Neighborhood Hits	11
SwissProt Accessions	Q3UHX2, Q3KQJ5	Gene names	Pdap1
Domain Architecture	No domain graphic available
Description	28 kDa heat- and acid-stable phosphoprotein (PDGF-associated protein) (PAP) (PDGFA-associated protein 1) (PAP1).

KI21B_HUMAN
θ value	4.03905 (rank : 203)	NC score	0.024760 (rank : 274)
Query Neighborhood Hits	277	Target Neighborhood Hits	1017	Shared Neighborhood Hits	54
SwissProt Accessions	O75037, Q5T4J3	Gene names	KIF21B, KIAA0449
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B.

NOG2_HUMAN
θ value	4.03905 (rank : 204)	NC score	0.015681 (rank : 295)
Query Neighborhood Hits	277	Target Neighborhood Hits	117	Shared Neighborhood Hits	10
SwissProt Accessions	Q13823, Q9BWN7	Gene names	GNL2, NGP1
Domain Architecture
Description	Nucleolar GTP-binding protein 2 (Autoantigen NGP-1).

TNNT2_HUMAN
θ value	4.03905 (rank : 205)	NC score	0.050780 (rank : 182)
Query Neighborhood Hits	277	Target Neighborhood Hits	433	Shared Neighborhood Hits	35
SwissProt Accessions	P45379, O60214, Q99596, Q99597, Q9UM96	Gene names	TNNT2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

TRM6_HUMAN
θ value	4.03905 (rank : 206)	NC score	0.044637 (rank : 199)
Query Neighborhood Hits	277	Target Neighborhood Hits	66	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UJA5, Q76P92, Q9BQV5, Q9ULR7	Gene names	TRM6, KIAA1153
Domain Architecture	No domain graphic available
Description	tRNA (adenine-N(1)-)-methyltransferase non-catalytic subunit TRM6 (tRNA(m1A58)-methyltransferase subunit TRM6) (tRNA(m1A58)MTase subunit TRM6).

ACINU_MOUSE
θ value	5.27518 (rank : 207)	NC score	0.048026 (rank : 190)
Query Neighborhood Hits	277	Target Neighborhood Hits	712	Shared Neighborhood Hits	69
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

AN30A_HUMAN
θ value	5.27518 (rank : 208)	NC score	0.024881 (rank : 272)
Query Neighborhood Hits	277	Target Neighborhood Hits	1119	Shared Neighborhood Hits	77
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

ANR11_HUMAN
θ value	5.27518 (rank : 209)	NC score	0.025888 (rank : 269)
Query Neighborhood Hits	277	Target Neighborhood Hits	1289	Shared Neighborhood Hits	89
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

CP053_MOUSE
θ value	5.27518 (rank : 210)	NC score	0.053808 (rank : 170)
Query Neighborhood Hits	277	Target Neighborhood Hits	38	Shared Neighborhood Hits	8
SwissProt Accessions	Q99L02	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf53 homolog.

CRNL1_MOUSE
θ value	5.27518 (rank : 211)	NC score	0.031525 (rank : 247)
Query Neighborhood Hits	277	Target Neighborhood Hits	72	Shared Neighborhood Hits	9
SwissProt Accessions	P63154, Q542E8, Q9CQC1	Gene names	Crnkl1
Domain Architecture	No domain graphic available
Description	Crooked neck-like protein 1 (Crooked neck homolog).

DDX21_HUMAN
θ value	5.27518 (rank : 212)	NC score	0.015252 (rank : 297)
Query Neighborhood Hits	277	Target Neighborhood Hits	308	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

GOGA4_HUMAN
θ value	5.27518 (rank : 213)	NC score	0.033683 (rank : 239)
Query Neighborhood Hits	277	Target Neighborhood Hits	2034	Shared Neighborhood Hits	119
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

HTSF1_HUMAN
θ value	5.27518 (rank : 214)	NC score	0.056057 (rank : 156)
Query Neighborhood Hits	277	Target Neighborhood Hits	408	Shared Neighborhood Hits	37
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

HXC10_HUMAN
θ value	5.27518 (rank : 215)	NC score	0.008322 (rank : 318)
Query Neighborhood Hits	277	Target Neighborhood Hits	417	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NYD6, O15219, O15220, Q9BVD5	Gene names	HOXC10
Domain Architecture
Description	Homeobox protein Hox-C10.

IF2M_MOUSE
θ value	5.27518 (rank : 216)	NC score	0.028474 (rank : 260)
Query Neighborhood Hits	277	Target Neighborhood Hits	183	Shared Neighborhood Hits	27
SwissProt Accessions	Q91YJ5	Gene names	Mtif2
Domain Architecture
Description	Translation initiation factor IF-2, mitochondrial precursor (IF-2Mt) (IF-2(Mt)).

LAP4_HUMAN
θ value	5.27518 (rank : 217)	NC score	0.003945 (rank : 322)
Query Neighborhood Hits	277	Target Neighborhood Hits	608	Shared Neighborhood Hits	18
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

MAP1B_HUMAN
θ value	5.27518 (rank : 218)	NC score	0.042937 (rank : 207)
Query Neighborhood Hits	277	Target Neighborhood Hits	903	Shared Neighborhood Hits	81
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MLL3_HUMAN
θ value	5.27518 (rank : 219)	NC score	0.033117 (rank : 243)
Query Neighborhood Hits	277	Target Neighborhood Hits	1644	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MYST4_MOUSE
θ value	5.27518 (rank : 220)	NC score	0.033292 (rank : 241)
Query Neighborhood Hits	277	Target Neighborhood Hits	416	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

NCF2_HUMAN
θ value	5.27518 (rank : 221)	NC score	0.048927 (rank : 186)
Query Neighborhood Hits	277	Target Neighborhood Hits	229	Shared Neighborhood Hits	15
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

NFM_HUMAN
θ value	5.27518 (rank : 222)	NC score	0.038616 (rank : 222)
Query Neighborhood Hits	277	Target Neighborhood Hits	1328	Shared Neighborhood Hits	98
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

SCN4A_HUMAN
θ value	5.27518 (rank : 223)	NC score	0.006828 (rank : 320)
Query Neighborhood Hits	277	Target Neighborhood Hits	133	Shared Neighborhood Hits	6
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

SFR12_HUMAN
θ value	5.27518 (rank : 224)	NC score	0.052586 (rank : 175)
Query Neighborhood Hits	277	Target Neighborhood Hits	553	Shared Neighborhood Hits	50
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

SPTA1_HUMAN
θ value	5.27518 (rank : 225)	NC score	0.010609 (rank : 311)
Query Neighborhood Hits	277	Target Neighborhood Hits	748	Shared Neighborhood Hits	34
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SYCP1_HUMAN
θ value	5.27518 (rank : 226)	NC score	0.031338 (rank : 248)
Query Neighborhood Hits	277	Target Neighborhood Hits	1313	Shared Neighborhood Hits	88
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

T2FA_HUMAN
θ value	5.27518 (rank : 227)	NC score	0.055973 (rank : 157)
Query Neighborhood Hits	277	Target Neighborhood Hits	228	Shared Neighborhood Hits	21
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

TCF8_MOUSE
θ value	5.27518 (rank : 228)	NC score	0.007756 (rank : 319)
Query Neighborhood Hits	277	Target Neighborhood Hits	1067	Shared Neighborhood Hits	39
SwissProt Accessions	Q64318, Q62519	Gene names	Tcf8, Zfhx1a, Zfx1a, Zfx1ha
Domain Architecture
Description	Transcription factor 8 (Zinc finger homeobox protein 1a) (MEB1) (Delta EF1).

TRI37_MOUSE
θ value	5.27518 (rank : 229)	NC score	0.018510 (rank : 290)
Query Neighborhood Hits	277	Target Neighborhood Hits	316	Shared Neighborhood Hits	22
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

VCX1_HUMAN
θ value	5.27518 (rank : 230)	NC score	0.057000 (rank : 152)
Query Neighborhood Hits	277	Target Neighborhood Hits	129	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H320, Q9P0H3	Gene names	VCX, VCX1, VCX10R, VCXB1
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 1 (VCX-B1 protein) (Variably charged protein X-B1) (Variable charge protein on X with ten repeats) (VCX- 10r).

AN32B_HUMAN
θ value	6.88961 (rank : 231)	NC score	0.041753 (rank : 210)
Query Neighborhood Hits	277	Target Neighborhood Hits	243	Shared Neighborhood Hits	23
SwissProt Accessions	Q92688, O00655, P78458, P78459	Gene names	ANP32B, APRIL, PHAPI2
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member B (PHAPI2 protein) (Silver-stainable protein SSP29) (Acidic protein rich in leucines).

AN32E_HUMAN
θ value	6.88961 (rank : 232)	NC score	0.039881 (rank : 218)
Query Neighborhood Hits	277	Target Neighborhood Hits	291	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BTT0, Q8N1S4, Q8WWW9	Gene names	ANP32E
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member E (LANP- like protein) (LANP-L).

ARS2_HUMAN
θ value	6.88961 (rank : 233)	NC score	0.040112 (rank : 216)
Query Neighborhood Hits	277	Target Neighborhood Hits	186	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BXP5, O95808, Q9BWP6, Q9BXP4	Gene names	ARS2, ASR2
Domain Architecture
Description	Arsenite-resistance protein 2.

CALD1_HUMAN
θ value	6.88961 (rank : 234)	NC score	0.042785 (rank : 208)
Query Neighborhood Hits	277	Target Neighborhood Hits	959	Shared Neighborhood Hits	76
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

CENPE_HUMAN
θ value	6.88961 (rank : 235)	NC score	0.030847 (rank : 252)
Query Neighborhood Hits	277	Target Neighborhood Hits	2060	Shared Neighborhood Hits	116
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CTCF_HUMAN
θ value	6.88961 (rank : 236)	NC score	-0.003524 (rank : 326)
Query Neighborhood Hits	277	Target Neighborhood Hits	764	Shared Neighborhood Hits	12
SwissProt Accessions	P49711	Gene names	CTCF
Domain Architecture
Description	Transcriptional repressor CTCF (CCCTC-binding factor) (CTCFL paralog) (11-zinc finger protein).

EHMT2_HUMAN
θ value	6.88961 (rank : 237)	NC score	0.013189 (rank : 305)
Query Neighborhood Hits	277	Target Neighborhood Hits	498	Shared Neighborhood Hits	31
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

FBLN2_MOUSE
θ value	6.88961 (rank : 238)	NC score	0.000031 (rank : 324)
Query Neighborhood Hits	277	Target Neighborhood Hits	505	Shared Neighborhood Hits	12
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

FKBP8_HUMAN
θ value	6.88961 (rank : 239)	NC score	0.222966 (rank : 51)
Query Neighborhood Hits	277	Target Neighborhood Hits	85	Shared Neighborhood Hits	44
SwissProt Accessions	Q14318	Gene names	FKBP8, FKBP38
Domain Architecture
Description	38 kDa FK506-binding protein homolog (FKBPR38) (FK506-binding protein 8).

K1967_HUMAN
θ value	6.88961 (rank : 240)	NC score	0.012503 (rank : 307)
Query Neighborhood Hits	277	Target Neighborhood Hits	136	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N163, Q6P0Q9, Q8N3G7, Q8N8M1, Q8TF34, Q9H9Q9, Q9HD12, Q9NT55	Gene names	KIAA1967, DBC1
Domain Architecture	No domain graphic available
Description	Protein KIAA1967 (Deleted in breast cancer gene 1 protein) (DBC.1) (DBC-1) (p30 DBC).

KI21B_MOUSE
θ value	6.88961 (rank : 241)	NC score	0.023021 (rank : 279)
Query Neighborhood Hits	277	Target Neighborhood Hits	997	Shared Neighborhood Hits	53
SwissProt Accessions	Q9QXL1, P97424	Gene names	Kif21b, Kif6
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B (Kinesin-like protein KIF6).

MBB1A_HUMAN
θ value	6.88961 (rank : 242)	NC score	0.038636 (rank : 220)
Query Neighborhood Hits	277	Target Neighborhood Hits	665	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

MYST3_HUMAN
θ value	6.88961 (rank : 243)	NC score	0.047424 (rank : 192)
Query Neighborhood Hits	277	Target Neighborhood Hits	772	Shared Neighborhood Hits	64
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

NCKX1_HUMAN
θ value	6.88961 (rank : 244)	NC score	0.033652 (rank : 240)
Query Neighborhood Hits	277	Target Neighborhood Hits	223	Shared Neighborhood Hits	27
SwissProt Accessions	O60721, O43485, O75184	Gene names	SLC24A1, KIAA0702, NCKX1
Domain Architecture
Description	Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) (Retinal rod Na-Ca+K exchanger).

NMT2_MOUSE
θ value	6.88961 (rank : 245)	NC score	0.008791 (rank : 316)
Query Neighborhood Hits	277	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	O70311	Gene names	Nmt2
Domain Architecture
Description	Glycylpeptide N-tetradecanoyltransferase 2 (EC 2.3.1.97) (Peptide N- myristoyltransferase 2) (Myristoyl-CoA:protein N-myristoyltransferase 2) (NMT 2) (Type II N-myristoyltransferase).

NP1L3_HUMAN
θ value	6.88961 (rank : 246)	NC score	0.027907 (rank : 262)
Query Neighborhood Hits	277	Target Neighborhood Hits	172	Shared Neighborhood Hits	27
SwissProt Accessions	Q99457, O60788	Gene names	NAP1L3, BNAP
Domain Architecture
Description	Nucleosome assembly protein 1-like 3.

RTN1_HUMAN
θ value	6.88961 (rank : 247)	NC score	0.023034 (rank : 278)
Query Neighborhood Hits	277	Target Neighborhood Hits	173	Shared Neighborhood Hits	12
SwissProt Accessions	Q16799, Q16800, Q16801	Gene names	RTN1, NSP
Domain Architecture
Description	Reticulon-1 (Neuroendocrine-specific protein).

TDRD6_MOUSE
θ value	6.88961 (rank : 248)	NC score	0.012678 (rank : 306)
Query Neighborhood Hits	277	Target Neighborhood Hits	82	Shared Neighborhood Hits	4
SwissProt Accessions	P61407	Gene names	Tdrd6
Domain Architecture
Description	Tudor domain-containing protein 6.

TNNT2_MOUSE
θ value	6.88961 (rank : 249)	NC score	0.038971 (rank : 219)
Query Neighborhood Hits	277	Target Neighborhood Hits	395	Shared Neighborhood Hits	33
SwissProt Accessions	P50752, Q64360, Q64377	Gene names	Tnnt2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

UHRF2_MOUSE
θ value	6.88961 (rank : 250)	NC score	0.014539 (rank : 301)
Query Neighborhood Hits	277	Target Neighborhood Hits	275	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

VCXC_HUMAN
θ value	6.88961 (rank : 251)	NC score	0.050455 (rank : 184)
Query Neighborhood Hits	277	Target Neighborhood Hits	139	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H321	Gene names	VCXC
Domain Architecture	No domain graphic available
Description	VCX-C protein (Variably charged protein X-C).

WDR43_HUMAN
θ value	6.88961 (rank : 252)	NC score	0.033741 (rank : 238)
Query Neighborhood Hits	277	Target Neighborhood Hits	269	Shared Neighborhood Hits	22
SwissProt Accessions	Q15061, Q15395, Q92577	Gene names	WDR43, KIAA0007
Domain Architecture	No domain graphic available
Description	WD repeat protein 43.

WDR60_MOUSE
θ value	6.88961 (rank : 253)	NC score	0.029327 (rank : 258)
Query Neighborhood Hits	277	Target Neighborhood Hits	344	Shared Neighborhood Hits	34
SwissProt Accessions	Q8C761, Q3UNM4	Gene names	Wdr60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

ZN326_MOUSE
θ value	6.88961 (rank : 254)	NC score	0.024592 (rank : 275)
Query Neighborhood Hits	277	Target Neighborhood Hits	117	Shared Neighborhood Hits	18
SwissProt Accessions	O88291, Q8BSJ5, Q8K1X9, Q9CYG9	Gene names	Znf326, Zan75, Zfp326
Domain Architecture	No domain graphic available
Description	Zinc finger protein 326 (Zinc finger protein-associated with nuclear matrix of 75 kDa).

ANK3_HUMAN
θ value	8.99809 (rank : 255)	NC score	0.011507 (rank : 310)
Query Neighborhood Hits	277	Target Neighborhood Hits	853	Shared Neighborhood Hits	67
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

ARI4A_HUMAN
θ value	8.99809 (rank : 256)	NC score	0.031021 (rank : 250)
Query Neighborhood Hits	277	Target Neighborhood Hits	434	Shared Neighborhood Hits	45
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

BPTF_HUMAN
θ value	8.99809 (rank : 257)	NC score	0.044388 (rank : 202)
Query Neighborhood Hits	277	Target Neighborhood Hits	786	Shared Neighborhood Hits	79
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

CCDC3_MOUSE
θ value	8.99809 (rank : 258)	NC score	0.019496 (rank : 289)
Query Neighborhood Hits	277	Target Neighborhood Hits	131	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D6Y1	Gene names	Ccdc3
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 3 precursor.

CENPH_MOUSE
θ value	8.99809 (rank : 259)	NC score	0.013775 (rank : 304)
Query Neighborhood Hits	277	Target Neighborhood Hits	195	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QYM8, Q8R3K9, Q9D079, Q9D0N1	Gene names	Cenph, Enp
Domain Architecture	No domain graphic available
Description	Centromere protein H (CENP-H).

CHD8_HUMAN
θ value	8.99809 (rank : 260)	NC score	0.022063 (rank : 281)
Query Neighborhood Hits	277	Target Neighborhood Hits	235	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

CPSF2_HUMAN
θ value	8.99809 (rank : 261)	NC score	0.015756 (rank : 294)
Query Neighborhood Hits	277	Target Neighborhood Hits	34	Shared Neighborhood Hits	7
SwissProt Accessions	Q9P2I0, Q6NSJ1, Q9H3W7	Gene names	CPSF2, CPSF100, KIAA1367
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 100 kDa subunit (CPSF 100 kDa subunit).

CPT1A_HUMAN
θ value	8.99809 (rank : 262)	NC score	0.003875 (rank : 323)
Query Neighborhood Hits	277	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	P50416, Q8TCU0, Q9BWK0	Gene names	CPT1A, CPT1
Domain Architecture
Description	Carnitine O-palmitoyltransferase I, liver isoform (EC 2.3.1.21) (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A).

CSPG3_HUMAN
θ value	8.99809 (rank : 263)	NC score	-0.001025 (rank : 325)
Query Neighborhood Hits	277	Target Neighborhood Hits	676	Shared Neighborhood Hits	11
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

HSP74_MOUSE
θ value	8.99809 (rank : 264)	NC score	0.015124 (rank : 298)
Query Neighborhood Hits	277	Target Neighborhood Hits	257	Shared Neighborhood Hits	30
SwissProt Accessions	Q61316	Gene names	Hspa4, Hsp110
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2).

IFIT3_HUMAN
θ value	8.99809 (rank : 265)	NC score	0.072298 (rank : 124)
Query Neighborhood Hits	277	Target Neighborhood Hits	83	Shared Neighborhood Hits	30
SwissProt Accessions	O14879, Q99634, Q9BSK7	Gene names	IFIT3, IFI60, IFIT4
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 3 (IFIT-3) (IFIT-4) (Interferon-induced 60 kDa protein) (IFI-60K) (ISG-60) (CIG49) (Retinoic acid-induced gene G protein) (RIG-G).

MLL3_MOUSE
θ value	8.99809 (rank : 266)	NC score	0.026275 (rank : 268)
Query Neighborhood Hits	277	Target Neighborhood Hits	1399	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

PININ_HUMAN
θ value	8.99809 (rank : 267)	NC score	0.044537 (rank : 201)
Query Neighborhood Hits	277	Target Neighborhood Hits	753	Shared Neighborhood Hits	76
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

PININ_MOUSE
θ value	8.99809 (rank : 268)	NC score	0.047728 (rank : 191)
Query Neighborhood Hits	277	Target Neighborhood Hits	777	Shared Neighborhood Hits	71
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

PRG4_MOUSE
θ value	8.99809 (rank : 269)	NC score	0.015078 (rank : 299)
Query Neighborhood Hits	277	Target Neighborhood Hits	624	Shared Neighborhood Hits	32
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SAFB1_HUMAN
θ value	8.99809 (rank : 270)	NC score	0.016529 (rank : 292)
Query Neighborhood Hits	277	Target Neighborhood Hits	493	Shared Neighborhood Hits	30
SwissProt Accessions	Q15424, O60406, Q59HH8	Gene names	SAFB, HAP, HET, SAFB1
Domain Architecture
Description	Scaffold attachment factor B (Scaffold attachment factor B1) (SAF-B) (HSP27 estrogen response element-TATA box-binding protein) (HSP27 ERE- TATA-binding protein).

SMRC1_MOUSE
θ value	8.99809 (rank : 271)	NC score	0.071540 (rank : 126)
Query Neighborhood Hits	277	Target Neighborhood Hits	459	Shared Neighborhood Hits	78
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

TF3C2_MOUSE
θ value	8.99809 (rank : 272)	NC score	0.013841 (rank : 303)
Query Neighborhood Hits	277	Target Neighborhood Hits	165	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BL74, Q3U7Z9, Q80XQ7, Q8BJJ4, Q8BLP3, Q8K1J1, Q9CSS0, Q9CVE6, Q9DBK6	Gene names	Gtf3c2, Kiaa0011
Domain Architecture
Description	General transcription factor 3C polypeptide 2 (Transcription factor IIIC-subunit beta) (TF3C-beta) (TFIIIC 110 kDa subunit) (TFIIIC110).

TOP1_HUMAN
θ value	8.99809 (rank : 273)	NC score	0.023954 (rank : 277)
Query Neighborhood Hits	277	Target Neighborhood Hits	207	Shared Neighborhood Hits	29
SwissProt Accessions	P11387, O43256, Q12855, Q12856, Q15610, Q5TFY3, Q9UJN0	Gene names	TOP1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

TOP1_MOUSE
θ value	8.99809 (rank : 274)	NC score	0.027305 (rank : 265)
Query Neighborhood Hits	277	Target Neighborhood Hits	213	Shared Neighborhood Hits	24
SwissProt Accessions	Q04750	Gene names	Top1, Top-1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

TPR_HUMAN
θ value	8.99809 (rank : 275)	NC score	0.037383 (rank : 225)
Query Neighborhood Hits	277	Target Neighborhood Hits	1921	Shared Neighborhood Hits	123
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

VCX3_HUMAN
θ value	8.99809 (rank : 276)	NC score	0.059495 (rank : 145)
Query Neighborhood Hits	277	Target Neighborhood Hits	105	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NNX9, Q9P0H4	Gene names	VCX3A, VCX3, VCX8R, VCXA
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 3 (VCX-A protein) (Variably charged protein X-A) (Variable charge protein on X with eight repeats) (VCX- 8r).

ZC313_HUMAN
θ value	8.99809 (rank : 277)	NC score	0.056261 (rank : 155)
Query Neighborhood Hits	277	Target Neighborhood Hits	772	Shared Neighborhood Hits	95
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

AIPL1_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.130701 (rank : 75)
Query Neighborhood Hits	277	Target Neighborhood Hits	113	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NZN9, Q9H873, Q9NS10	Gene names	AIPL1
Domain Architecture
Description	Aryl-hydrocarbon-interacting protein-like 1.

AIPL1_MOUSE
θ value	θ > 10 (rank : 279)	NC score	0.123834 (rank : 76)
Query Neighborhood Hits	277	Target Neighborhood Hits	45	Shared Neighborhood Hits	30
SwissProt Accessions	Q924K1	Gene names	Aipl1
Domain Architecture
Description	Aryl-hydrocarbon-interacting protein-like 1.

AIP_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.114545 (rank : 84)
Query Neighborhood Hits	277	Target Neighborhood Hits	51	Shared Neighborhood Hits	31
SwissProt Accessions	O00170, Q99606	Gene names	AIP, XAP2
Domain Architecture
Description	AH receptor-interacting protein (AIP) (Aryl-hydrocarbon receptor- interacting protein) (Immunophilin homolog ARA9) (HBV-X-associated protein 2).

AIP_MOUSE
θ value	θ > 10 (rank : 281)	NC score	0.112631 (rank : 86)
Query Neighborhood Hits	277	Target Neighborhood Hits	51	Shared Neighborhood Hits	32
SwissProt Accessions	O08915	Gene names	Aip
Domain Architecture
Description	AH receptor-interacting protein (AIP) (Aryl-hydrocarbon receptor- interacting protein).

AKA12_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.097300 (rank : 97)
Query Neighborhood Hits	277	Target Neighborhood Hits	825	Shared Neighborhood Hits	133
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

APC7_HUMAN
θ value	θ > 10 (rank : 283)	NC score	0.079876 (rank : 111)
Query Neighborhood Hits	277	Target Neighborhood Hits	57	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UJX3, Q96AC4, Q96GF4, Q9BU24, Q9NT16	Gene names	ANAPC7, APC7
Domain Architecture
Description	Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7).

APC7_MOUSE
θ value	θ > 10 (rank : 284)	NC score	0.078480 (rank : 114)
Query Neighborhood Hits	277	Target Neighborhood Hits	56	Shared Neighborhood Hits	27
SwissProt Accessions	Q9WVM3, Q3UBM7, Q8BSR2, Q91W13	Gene names	Anapc7, Apc7
Domain Architecture
Description	Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7) (Prediabetic NOD sera-reactive autoantigen).

ASPH_HUMAN
θ value	θ > 10 (rank : 285)	NC score	0.055454 (rank : 160)
Query Neighborhood Hits	277	Target Neighborhood Hits	158	Shared Neighborhood Hits	52
SwissProt Accessions	Q12797	Gene names	ASPH
Domain Architecture
Description	Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16) (Aspartate beta- hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta- dioxygenase).

CC47_MOUSE
θ value	θ > 10 (rank : 286)	NC score	0.054098 (rank : 167)
Query Neighborhood Hits	277	Target Neighborhood Hits	245	Shared Neighborhood Hits	74
SwissProt Accessions	Q9D024, Q3TSB5, Q3V1S7, Q8C5D9, Q920S6	Gene names	Ccdc47, Asp4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor (Adipocyte-specific protein 4).

CTR9_HUMAN
θ value	θ > 10 (rank : 287)	NC score	0.083303 (rank : 106)
Query Neighborhood Hits	277	Target Neighborhood Hits	383	Shared Neighborhood Hits	63
SwissProt Accessions	Q6PD62, Q15015	Gene names	CTR9, KIAA0155, SH2BP1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1).

CTR9_MOUSE
θ value	θ > 10 (rank : 288)	NC score	0.083917 (rank : 105)
Query Neighborhood Hits	277	Target Neighborhood Hits	427	Shared Neighborhood Hits	67
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

DMP1_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.054905 (rank : 164)
Query Neighborhood Hits	277	Target Neighborhood Hits	491	Shared Neighborhood Hits	77
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

DMP1_MOUSE
θ value	θ > 10 (rank : 290)	NC score	0.050875 (rank : 181)
Query Neighborhood Hits	277	Target Neighborhood Hits	498	Shared Neighborhood Hits	82
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

ERIC1_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.108156 (rank : 89)
Query Neighborhood Hits	277	Target Neighborhood Hits	364	Shared Neighborhood Hits	93
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

FKBP6_MOUSE
θ value	θ > 10 (rank : 292)	NC score	0.058495 (rank : 148)
Query Neighborhood Hits	277	Target Neighborhood Hits	37	Shared Neighborhood Hits	13
SwissProt Accessions	Q91XW8, Q91Y30	Gene names	Fkbp6
Domain Architecture
Description	FK506-binding protein 6 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (36 kDa FK506-binding protein) (FKBP- 36) (Immunophilin FKBP36).

IFIT1_MOUSE
θ value	θ > 10 (rank : 293)	NC score	0.050192 (rank : 185)
Query Neighborhood Hits	277	Target Neighborhood Hits	59	Shared Neighborhood Hits	25
SwissProt Accessions	Q64282	Gene names	Ifit1, Garg16, Ifi56
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 1 (IFIT-1) (Interferon-induced 56 kDa protein) (IFI-56K) (Glucocorticoid- attenuated response gene 16 protein) (GARG-16).

IFT88_HUMAN
θ value	θ > 10 (rank : 294)	NC score	0.120734 (rank : 77)
Query Neighborhood Hits	277	Target Neighborhood Hits	122	Shared Neighborhood Hits	42
SwissProt Accessions	Q13099	Gene names	IFT88, TG737, TTC10
Domain Architecture
Description	Intraflagellar transport 88 homolog (Tetratricopeptide repeat protein 10) (TPR repeat protein 10) (Recessive polycystic kidney disease protein Tg737 homolog).

IFT88_MOUSE
θ value	θ > 10 (rank : 295)	NC score	0.114568 (rank : 83)
Query Neighborhood Hits	277	Target Neighborhood Hits	124	Shared Neighborhood Hits	41
SwissProt Accessions	Q61371	Gene names	Ift88, Tg737, Tg737Rpw, TgN737Rpw, Ttc10
Domain Architecture
Description	Intraflagellar transport 88 homolog (Tetratricopeptide repeat protein 10) (TPR repeat protein 10) (Recessive polycystic kidney disease protein Tg737) (TgN(Imorpk)737Rpw).

IWS1_HUMAN
θ value	θ > 10 (rank : 296)	NC score	0.099744 (rank : 94)
Query Neighborhood Hits	277	Target Neighborhood Hits	1241	Shared Neighborhood Hits	144
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

K0372_HUMAN
θ value	θ > 10 (rank : 297)	NC score	0.163124 (rank : 61)
Query Neighborhood Hits	277	Target Neighborhood Hits	136	Shared Neighborhood Hits	53
SwissProt Accessions	Q6PGP7, O15077, Q6PJI3	Gene names	KIAA0372
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein KIAA0372 (TPR repeat protein KIAA0372).

LEO1_MOUSE
θ value	θ > 10 (rank : 298)	NC score	0.114442 (rank : 85)
Query Neighborhood Hits	277	Target Neighborhood Hits	946	Shared Neighborhood Hits	143
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

NCOR1_HUMAN
θ value	θ > 10 (rank : 299)	NC score	0.055463 (rank : 159)
Query Neighborhood Hits	277	Target Neighborhood Hits	577	Shared Neighborhood Hits	61
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

NIPBL_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.059700 (rank : 144)
Query Neighborhood Hits	277	Target Neighborhood Hits	1311	Shared Neighborhood Hits	130
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NPBL_MOUSE
θ value	θ > 10 (rank : 301)	NC score	0.051905 (rank : 177)
Query Neighborhood Hits	277	Target Neighborhood Hits	1041	Shared Neighborhood Hits	107
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

NSBP1_HUMAN
θ value	θ > 10 (rank : 302)	NC score	0.057944 (rank : 149)
Query Neighborhood Hits	277	Target Neighborhood Hits	251	Shared Neighborhood Hits	31
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

PPID_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.144352 (rank : 69)
Query Neighborhood Hits	277	Target Neighborhood Hits	92	Shared Neighborhood Hits	47
SwissProt Accessions	Q08752	Gene names	PPID, CYP40, CYPD
Domain Architecture
Description	40 kDa peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-40) (CYP-40) (Cyclophilin-related protein).

PPID_MOUSE
θ value	θ > 10 (rank : 304)	NC score	0.134724 (rank : 72)
Query Neighborhood Hits	277	Target Neighborhood Hits	98	Shared Neighborhood Hits	46
SwissProt Accessions	Q9CR16, Q543G1	Gene names	Ppid
Domain Architecture
Description	40 kDa peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-40) (CYP-40).

PTMS_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.054431 (rank : 165)
Query Neighborhood Hits	277	Target Neighborhood Hits	111	Shared Neighborhood Hits	17
SwissProt Accessions	P20962	Gene names	PTMS
Domain Architecture	No domain graphic available
Description	Parathymosin.

RBBP6_HUMAN
θ value	θ > 10 (rank : 306)	NC score	0.051665 (rank : 179)
Query Neighborhood Hits	277	Target Neighborhood Hits	1135	Shared Neighborhood Hits	107
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

SEC63_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.077005 (rank : 116)
Query Neighborhood Hits	277	Target Neighborhood Hits	586	Shared Neighborhood Hits	118
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

SEC63_MOUSE
θ value	θ > 10 (rank : 308)	NC score	0.080538 (rank : 109)
Query Neighborhood Hits	277	Target Neighborhood Hits	601	Shared Neighborhood Hits	118
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

SMRC1_HUMAN
θ value	θ > 10 (rank : 309)	NC score	0.058889 (rank : 146)
Query Neighborhood Hits	277	Target Neighborhood Hits	375	Shared Neighborhood Hits	57
SwissProt Accessions	Q92922, Q6P172, Q8IWH2	Gene names	SMARCC1, BAF155
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155).

SMYD4_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.074697 (rank : 120)
Query Neighborhood Hits	277	Target Neighborhood Hits	81	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IYR2, Q8N1P2, Q8NAT0, Q96LV4, Q96PV2	Gene names	SMYD4, KIAA1936
Domain Architecture	No domain graphic available
Description	SET and MYND domain-containing protein 4.

SMYD4_MOUSE
θ value	θ > 10 (rank : 311)	NC score	0.080260 (rank : 110)
Query Neighborhood Hits	277	Target Neighborhood Hits	85	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BTK5, Q3U3Z8, Q501N5, Q5SWN4, Q69Z60, Q8BMP3	Gene names	Smyd4, Kiaa1936
Domain Architecture	No domain graphic available
Description	SET and MYND domain-containing protein 4.

TCAL3_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.057822 (rank : 151)
Query Neighborhood Hits	277	Target Neighborhood Hits	274	Shared Neighborhood Hits	78
SwissProt Accessions	Q969E4	Gene names	TCEAL3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

TCAL5_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.102417 (rank : 93)
Query Neighborhood Hits	277	Target Neighborhood Hits	806	Shared Neighborhood Hits	138
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

TF3C3_HUMAN
θ value	θ > 10 (rank : 314)	NC score	0.115024 (rank : 82)
Query Neighborhood Hits	277	Target Neighborhood Hits	90	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y5Q9, Q86XJ8, Q8WX84, Q96B44, Q9H5I8, Q9NT97	Gene names	GTF3C3
Domain Architecture
Description	General transcription factor 3C polypeptide 3 (Transcription factor IIIC-subunit gamma) (TF3C-gamma) (TFIIIC 102 kDa subunit) (TFIIIC102).

TGON2_HUMAN
θ value	θ > 10 (rank : 315)	NC score	0.059883 (rank : 143)
Query Neighborhood Hits	277	Target Neighborhood Hits	1037	Shared Neighborhood Hits	99
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TTC14_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.166987 (rank : 60)
Query Neighborhood Hits	277	Target Neighborhood Hits	274	Shared Neighborhood Hits	59
SwissProt Accessions	Q96N46, Q6UWJ7, Q8TF22	Gene names	TTC14, KIAA1980
Domain Architecture
Description	Tetratricopeptide repeat protein 14 (TPR repeat protein 14).

TTC28_HUMAN
θ value	θ > 10 (rank : 317)	NC score	0.053504 (rank : 172)
Query Neighborhood Hits	277	Target Neighborhood Hits	271	Shared Neighborhood Hits	38
SwissProt Accessions	Q96AY4, O95928, O95929, Q9NTE4, Q9UG31, Q9UGG5, Q9UPV8, Q9Y3S5	Gene names	TTC28, KIAA1043
Domain Architecture
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

TTC28_MOUSE
θ value	θ > 10 (rank : 318)	NC score	0.053643 (rank : 171)
Query Neighborhood Hits	277	Target Neighborhood Hits	194	Shared Neighborhood Hits	31
SwissProt Accessions	Q80XJ3, Q6P9J6, Q80TL5, Q8BV10, Q8C0F2	Gene names	Ttc28, Kiaa1043
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

TTC3_HUMAN
θ value	θ > 10 (rank : 319)	NC score	0.171767 (rank : 59)
Query Neighborhood Hits	277	Target Neighborhood Hits	664	Shared Neighborhood Hits	73
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

TTC4_MOUSE
θ value	θ > 10 (rank : 320)	NC score	0.283276 (rank : 41)
Query Neighborhood Hits	277	Target Neighborhood Hits	85	Shared Neighborhood Hits	46
SwissProt Accessions	Q8R3H9	Gene names	Ttc4
Domain Architecture
Description	Tetratricopeptide repeat protein 4 (TPR repeat protein 4).

TXND2_HUMAN
θ value	θ > 10 (rank : 321)	NC score	0.050759 (rank : 183)
Query Neighborhood Hits	277	Target Neighborhood Hits	793	Shared Neighborhood Hits	94
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

TXND2_MOUSE
θ value	θ > 10 (rank : 322)	NC score	0.067914 (rank : 133)
Query Neighborhood Hits	277	Target Neighborhood Hits	828	Shared Neighborhood Hits	118
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

VPS72_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.051371 (rank : 180)
Query Neighborhood Hits	277	Target Neighborhood Hits	274	Shared Neighborhood Hits	74
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

VPS72_MOUSE
θ value	θ > 10 (rank : 324)	NC score	0.052421 (rank : 176)
Query Neighborhood Hits	277	Target Neighborhood Hits	286	Shared Neighborhood Hits	76
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

Z3H7A_HUMAN
θ value	θ > 10 (rank : 325)	NC score	0.161174 (rank : 63)
Query Neighborhood Hits	277	Target Neighborhood Hits	105	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IWR0, Q9NPE9	Gene names	ZC3H7A, ZC3H7, ZC3HDC7
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH-type domain-containing protein 7A.

Z3H7B_HUMAN
θ value	θ > 10 (rank : 326)	NC score	0.203719 (rank : 55)
Query Neighborhood Hits	277	Target Neighborhood Hits	109	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UGR2, Q5TFX9, Q8TBT9, Q9H8B6, Q9UGQ9, Q9UGR0, Q9UGR1, Q9UK03, Q9UPW9	Gene names	ZC3H7B, KIAA1031
Domain Architecture
Description	Zinc finger CCCH-type domain-containing protein 7B (Rotavirus 'X'- associated non-structural protein) (RoXaN).

Hits sorted by NC score

F10A5_HUMAN
NC score	0.999962 (rank : 1)	θ value	2.49938e-159 (rank : 1)
Query Neighborhood Hits	277	Target Neighborhood Hits	277	Shared Neighborhood Hits	277
SwissProt Accessions	Q8NFI4	Gene names	FAM10A5
Domain Architecture	No domain graphic available
Description	Protein FAM10A5.

F10A1_HUMAN
NC score	0.985883 (rank : 2)	θ value	9.82853e-156 (rank : 2)
Query Neighborhood Hits	277	Target Neighborhood Hits	312	Shared Neighborhood Hits	241
SwissProt Accessions	P50502, O14999	Gene names	ST13, FAM10A1, HIP, SNC6
Domain Architecture
Description	Hsc70-interacting protein (Hip) (Suppression of tumorigenicity protein 13) (Putative tumor suppressor ST13) (Protein FAM10A1) (Progesterone receptor-associated p48 protein) (NY-REN-33 antigen).

F10A4_HUMAN
NC score	0.962810 (rank : 3)	θ value	3.4095e-124 (rank : 4)
Query Neighborhood Hits	277	Target Neighborhood Hits	249	Shared Neighborhood Hits	172
SwissProt Accessions	Q8IZP2	Gene names	FAM10A4
Domain Architecture	No domain graphic available
Description	Protein FAM10A4.

F10A1_MOUSE
NC score	0.948688 (rank : 4)	θ value	1.33764e-128 (rank : 3)
Query Neighborhood Hits	277	Target Neighborhood Hits	117	Shared Neighborhood Hits	80
SwissProt Accessions	Q99L47, Q4FJT4	Gene names	St13, Fam10a1, Hip
Domain Architecture
Description	Hsc70-interacting protein (Hip) (Protein ST13 homolog) (Protein FAM10A1).

SGTA_MOUSE
NC score	0.570454 (rank : 5)	θ value	2.13673e-09 (rank : 8)
Query Neighborhood Hits	277	Target Neighborhood Hits	112	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BJU0, Q8BGA6, Q99L52	Gene names	Sgta, Sgt
Domain Architecture
Description	Small glutamine-rich tetratricopeptide repeat-containing protein A.

SGTB_HUMAN
NC score	0.565784 (rank : 6)	θ value	4.76016e-09 (rank : 10)
Query Neighborhood Hits	277	Target Neighborhood Hits	96	Shared Neighborhood Hits	59
SwissProt Accessions	Q96EQ0	Gene names	SGTB, SGT2
Domain Architecture
Description	Small glutamine-rich tetratricopeptide repeat-containing protein B (Small glutamine-rich protein with tetratricopeptide repeats 2).

SGTB_MOUSE
NC score	0.565385 (rank : 7)	θ value	1.38499e-08 (rank : 11)
Query Neighborhood Hits	277	Target Neighborhood Hits	90	Shared Neighborhood Hits	58
SwissProt Accessions	Q8VD33	Gene names	Sgtb
Domain Architecture	No domain graphic available
Description	Small glutamine-rich tetratricopeptide repeat-containing protein B.

TOM70_MOUSE
NC score	0.563849 (rank : 8)	θ value	1.25267e-09 (rank : 7)
Query Neighborhood Hits	277	Target Neighborhood Hits	102	Shared Neighborhood Hits	56
SwissProt Accessions	Q9CZW5	Gene names	Tomm70a, D16Wsu109e
Domain Architecture
Description	Mitochondrial precursor proteins import receptor (Translocase of outer membrane TOM70).

TOM70_HUMAN
NC score	0.561477 (rank : 9)	θ value	9.59137e-10 (rank : 6)
Query Neighborhood Hits	277	Target Neighborhood Hits	127	Shared Neighborhood Hits	59
SwissProt Accessions	O94826	Gene names	TOMM70A, KIAA0719
Domain Architecture
Description	Mitochondrial precursor proteins import receptor (Translocase of outer membrane TOM70).

TTC1_MOUSE
NC score	0.552153 (rank : 10)	θ value	4.0297e-08 (rank : 12)
Query Neighborhood Hits	277	Target Neighborhood Hits	145	Shared Neighborhood Hits	63
SwissProt Accessions	Q91Z38, Q3TLM0	Gene names	Ttc1
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

SPAG1_HUMAN
NC score	0.550456 (rank : 11)	θ value	2.0648e-12 (rank : 5)
Query Neighborhood Hits	277	Target Neighborhood Hits	197	Shared Neighborhood Hits	70
SwissProt Accessions	Q07617, Q7Z5G1	Gene names	SPAG1
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 1 (Infertility-related sperm protein Spag-1) (HSD-3.8).

STUB1_MOUSE
NC score	0.545517 (rank : 12)	θ value	2.61198e-07 (rank : 14)
Query Neighborhood Hits	277	Target Neighborhood Hits	97	Shared Neighborhood Hits	57
SwissProt Accessions	Q9WUD1, Q9DCJ0	Gene names	Stub1, Chip
Domain Architecture	No domain graphic available
Description	STIP1 homology and U box-containing protein 1 (EC 6.3.2.-) (STIP1 homology and U-box-containing protein 1) (Carboxy terminus of Hsp70- interacting protein) (E3 ubiquitin protein ligase CHIP).

SGTA_HUMAN
NC score	0.545143 (rank : 13)	θ value	7.59969e-07 (rank : 17)
Query Neighborhood Hits	277	Target Neighborhood Hits	105	Shared Neighborhood Hits	60
SwissProt Accessions	O43765, Q9BTZ9	Gene names	SGTA, SGT
Domain Architecture
Description	Small glutamine-rich tetratricopeptide repeat-containing protein A (Vpu-binding protein) (UBP).

SPAG1_MOUSE
NC score	0.539591 (rank : 14)	θ value	2.13673e-09 (rank : 9)
Query Neighborhood Hits	277	Target Neighborhood Hits	218	Shared Neighborhood Hits	81
SwissProt Accessions	Q80ZX8, Q8CCK7, Q9QZJ3, Q9QZJ4	Gene names	Spag1, Tpis
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 1 (Infertility-related sperm protein Spag-1) (TPR-containing protein involved in spermatogenesis) (TPIS).

STUB1_HUMAN
NC score	0.528933 (rank : 15)	θ value	4.92598e-06 (rank : 21)
Query Neighborhood Hits	277	Target Neighborhood Hits	99	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UNE7, O60526, Q969U2, Q9HBT1	Gene names	STUB1, CHIP
Domain Architecture	No domain graphic available
Description	STIP1 homology and U box-containing protein 1 (EC 6.3.2.-) (STIP1 homology and U-box-containing protein 1) (Carboxy terminus of Hsp70- interacting protein) (E3 ubiquitin protein ligase CHIP) (CLL- associated antigen KW-8) (Antigen NY-CO-7).

TTC1_HUMAN
NC score	0.527177 (rank : 16)	θ value	7.59969e-07 (rank : 18)
Query Neighborhood Hits	277	Target Neighborhood Hits	417	Shared Neighborhood Hits	133
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

STIP1_MOUSE
NC score	0.523283 (rank : 17)	θ value	2.61198e-07 (rank : 13)
Query Neighborhood Hits	277	Target Neighborhood Hits	154	Shared Neighborhood Hits	61
SwissProt Accessions	Q60864, Q3TT16, Q8BPH3, Q99L66	Gene names	Stip1
Domain Architecture	No domain graphic available
Description	Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (mSTI1).

STIP1_HUMAN
NC score	0.520212 (rank : 18)	θ value	3.41135e-07 (rank : 16)
Query Neighborhood Hits	277	Target Neighborhood Hits	147	Shared Neighborhood Hits	60
SwissProt Accessions	P31948	Gene names	STIP1
Domain Architecture
Description	Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (Transformation-sensitive protein IEF SSP 3521) (NY- REN-11 antigen).

TTC12_MOUSE
NC score	0.474729 (rank : 19)	θ value	1.09739e-05 (rank : 22)
Query Neighborhood Hits	277	Target Neighborhood Hits	98	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BW49	Gene names	Ttc12
Domain Architecture
Description	Tetratricopeptide repeat protein 12 (TPR repeat protein 12).

OM34_HUMAN
NC score	0.468416 (rank : 20)	θ value	0.00102713 (rank : 28)
Query Neighborhood Hits	277	Target Neighborhood Hits	82	Shared Neighborhood Hits	53
SwissProt Accessions	Q15785, Q9NTZ3	Gene names	TOMM34
Domain Architecture
Description	Mitochondrial import receptor subunit TOM34 (Translocase of outer membrane 34 kDa subunit) (hTom34).

TTC12_HUMAN
NC score	0.468057 (rank : 21)	θ value	0.000121331 (rank : 24)
Query Neighborhood Hits	277	Target Neighborhood Hits	125	Shared Neighborhood Hits	54
SwissProt Accessions	Q9H892, Q8N5H9, Q9NWY3	Gene names	TTC12
Domain Architecture
Description	Tetratricopeptide repeat protein 12 (TPR repeat protein 12).

OM34_MOUSE
NC score	0.461802 (rank : 22)	θ value	0.00665767 (rank : 33)
Query Neighborhood Hits	277	Target Neighborhood Hits	82	Shared Neighborhood Hits	52
SwissProt Accessions	Q9CYG7, Q3THD0, Q9D059	Gene names	Tomm34
Domain Architecture
Description	Mitochondrial import receptor subunit TOM34 (Translocase of outer membrane 34 kDa subunit).

DYXC1_MOUSE
NC score	0.450739 (rank : 23)	θ value	0.000158464 (rank : 25)
Query Neighborhood Hits	277	Target Neighborhood Hits	172	Shared Neighborhood Hits	58
SwissProt Accessions	Q8R368	Gene names	Dyx1c1, Ekn1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein homolog.

DYXC1_HUMAN
NC score	0.424247 (rank : 24)	θ value	0.00298849 (rank : 32)
Query Neighborhood Hits	277	Target Neighborhood Hits	261	Shared Neighborhood Hits	75
SwissProt Accessions	Q8WXU2, Q6P5Y9	Gene names	DYX1C1, EKN1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein.

TTC6_HUMAN
NC score	0.405701 (rank : 25)	θ value	0.000602161 (rank : 27)
Query Neighborhood Hits	277	Target Neighborhood Hits	103	Shared Neighborhood Hits	59
SwissProt Accessions	Q86TZ1, Q96CE6	Gene names	TTC6
Domain Architecture
Description	Tetratricopeptide repeat protein 6 (TPR repeat protein 6).

DNJC7_HUMAN
NC score	0.391413 (rank : 26)	θ value	4.92598e-06 (rank : 19)
Query Neighborhood Hits	277	Target Neighborhood Hits	212	Shared Neighborhood Hits	63
SwissProt Accessions	Q99615	Gene names	DNAJC7, TPR2, TTC2
Domain Architecture
Description	DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2).

DNJC7_MOUSE
NC score	0.386982 (rank : 27)	θ value	2.44474e-05 (rank : 23)
Query Neighborhood Hits	277	Target Neighborhood Hits	211	Shared Neighborhood Hits	63
SwissProt Accessions	Q9QYI3, Q3TKR1, Q8BPG3, Q8CIL2, Q9CT29, Q9D026	Gene names	Dnajc7, Ttc2
Domain Architecture
Description	DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2) (MDj11).

SUGT1_MOUSE
NC score	0.369444 (rank : 28)	θ value	0.00869519 (rank : 34)
Query Neighborhood Hits	277	Target Neighborhood Hits	73	Shared Neighborhood Hits	48
SwissProt Accessions	Q9CX34, Q3UF88, Q9CRE7, Q9D8M6	Gene names	Sugt1
Domain Architecture
Description	Suppressor of G2 allele of SKP1 homolog.

OGT1_HUMAN
NC score	0.339261 (rank : 29)	θ value	0.00020696 (rank : 26)
Query Neighborhood Hits	277	Target Neighborhood Hits	143	Shared Neighborhood Hits	51
SwissProt Accessions	O15294, Q7Z3K0, Q8WWM8, Q96CC1, Q9UG57	Gene names	OGT
Domain Architecture
Description	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.-) (O-GlcNAc transferase p110 subunit).

UN45A_MOUSE
NC score	0.335464 (rank : 30)	θ value	0.0148317 (rank : 35)
Query Neighborhood Hits	277	Target Neighborhood Hits	129	Shared Neighborhood Hits	56
SwissProt Accessions	Q99KD5, Q3TKV6, Q8BFT3, Q8C157	Gene names	Unc45a, Smap1
Domain Architecture	No domain graphic available
Description	UNC45 homolog A (UNC-45A) (Stromal membrane-associated protein 1) (Smap-1).

PPP5_HUMAN
NC score	0.318817 (rank : 31)	θ value	3.41135e-07 (rank : 15)
Query Neighborhood Hits	277	Target Neighborhood Hits	101	Shared Neighborhood Hits	54
SwissProt Accessions	P53041, Q16722	Gene names	PPP5C, PPP5
Domain Architecture
Description	Serine/threonine-protein phosphatase 5 (EC 3.1.3.16) (PP5) (Protein phosphatase T) (PP-T) (PPT).

TTC4_HUMAN
NC score	0.313089 (rank : 32)	θ value	1.06291 (rank : 133)
Query Neighborhood Hits	277	Target Neighborhood Hits	75	Shared Neighborhood Hits	46
SwissProt Accessions	O95801, Q9H3I2	Gene names	TTC4
Domain Architecture
Description	Tetratricopeptide repeat protein 4 (TPR repeat protein 4).

PPP5_MOUSE
NC score	0.312621 (rank : 33)	θ value	4.92598e-06 (rank : 20)
Query Neighborhood Hits	277	Target Neighborhood Hits	100	Shared Neighborhood Hits	54
SwissProt Accessions	Q60676, O35299	Gene names	Ppp5c
Domain Architecture
Description	Serine/threonine-protein phosphatase 5 (EC 3.1.3.16) (PP5) (Protein phosphatase T) (PPT).

SUGT1_HUMAN
NC score	0.303841 (rank : 34)	θ value	0.0431538 (rank : 43)
Query Neighborhood Hits	277	Target Neighborhood Hits	66	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y2Z0, Q5JAK5, Q6VXY6	Gene names	SUGT1
Domain Architecture
Description	Suppressor of G2 allele of SKP1 homolog (Sgt1) (Putative 40-6-3 protein).

UN45B_HUMAN
NC score	0.299773 (rank : 35)	θ value	0.21417 (rank : 73)
Query Neighborhood Hits	277	Target Neighborhood Hits	97	Shared Neighborhood Hits	47
SwissProt Accessions	Q8IWX7, Q495Q8, Q495Q9	Gene names	UNC45B, CMYA4, UNC45
Domain Architecture	No domain graphic available
Description	UNC45 homolog B (UNC-45B).

UN45B_MOUSE
NC score	0.296659 (rank : 36)	θ value	0.62314 (rank : 102)
Query Neighborhood Hits	277	Target Neighborhood Hits	90	Shared Neighborhood Hits	46
SwissProt Accessions	Q8CGY6, Q5XG72, Q8BHC5, Q8BWK3	Gene names	Unc45b, Cmya4
Domain Architecture	No domain graphic available
Description	UNC45 homolog B (UNC-45B).

DNJC3_MOUSE
NC score	0.289804 (rank : 37)	θ value	0.00175202 (rank : 30)
Query Neighborhood Hits	277	Target Neighborhood Hits	230	Shared Neighborhood Hits	65
SwissProt Accessions	Q91YW3, Q60873	Gene names	Dnajc3, P58ipk
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 3 (Interferon-induced, double-stranded RNA-activated protein kinase inhibitor) (Protein kinase inhibitor p58) (Protein kinase inhibitor of 58 kDa).

UN45A_HUMAN
NC score	0.289518 (rank : 38)	θ value	0.813845 (rank : 117)
Query Neighborhood Hits	277	Target Neighborhood Hits	122	Shared Neighborhood Hits	50
SwissProt Accessions	Q9H3U1, Q7L3Y6, Q9H3U8, Q9NSE8, Q9NSE9	Gene names	UNC45A, SMAP1
Domain Architecture	No domain graphic available
Description	UNC45 homolog A (UNC-45A) (Smooth muscle cell-associated protein 1) (SMAP-1).

CDC27_HUMAN
NC score	0.288194 (rank : 39)	θ value	0.00228821 (rank : 31)
Query Neighborhood Hits	277	Target Neighborhood Hits	139	Shared Neighborhood Hits	49
SwissProt Accessions	P30260, Q16349, Q96F35	Gene names	CDC27
Domain Architecture
Description	Cell division cycle protein 27 homolog (CDC27Hs) (H-NUC).

DNJC3_HUMAN
NC score	0.285701 (rank : 40)	θ value	0.00175202 (rank : 29)
Query Neighborhood Hits	277	Target Neighborhood Hits	223	Shared Neighborhood Hits	60
SwissProt Accessions	Q13217, Q86WT9, Q8N4N2	Gene names	DNAJC3, P58IPK, PRKRI
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 3 (Interferon-induced, double-stranded RNA-activated protein kinase inhibitor) (Protein kinase inhibitor p58) (Protein kinase inhibitor of 58 kDa).

TTC4_MOUSE
NC score	0.283276 (rank : 41)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	277	Target Neighborhood Hits	85	Shared Neighborhood Hits	46
SwissProt Accessions	Q8R3H9	Gene names	Ttc4
Domain Architecture
Description	Tetratricopeptide repeat protein 4 (TPR repeat protein 4).

TTC13_HUMAN
NC score	0.277317 (rank : 42)	θ value	0.279714 (rank : 80)
Query Neighborhood Hits	277	Target Neighborhood Hits	117	Shared Neighborhood Hits	57
SwissProt Accessions	Q8NBP0, Q8IVP8, Q8NBI0, Q8ND20	Gene names	TTC13
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 13 (TPR repeat protein 13).

WDTC1_MOUSE
NC score	0.269923 (rank : 43)	θ value	0.0193708 (rank : 37)
Query Neighborhood Hits	277	Target Neighborhood Hits	298	Shared Neighborhood Hits	44
SwissProt Accessions	Q80ZK9	Gene names	Wdtc1
Domain Architecture
Description	WD and tetratricopeptide repeats protein 1.

WDTC1_HUMAN
NC score	0.262399 (rank : 44)	θ value	0.0736092 (rank : 50)
Query Neighborhood Hits	277	Target Neighborhood Hits	299	Shared Neighborhood Hits	45
SwissProt Accessions	Q8N5D0, Q9NV87, Q9UPW4	Gene names	WDTC1, KIAA1037
Domain Architecture
Description	WD and tetratricopeptide repeats protein 1.

FKBP5_HUMAN
NC score	0.250773 (rank : 45)	θ value	0.365318 (rank : 85)
Query Neighborhood Hits	277	Target Neighborhood Hits	107	Shared Neighborhood Hits	52
SwissProt Accessions	Q13451	Gene names	FKBP5, AIG6, FKBP51
Domain Architecture
Description	FK506-binding protein 5 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (51 kDa FK506-binding protein) (FKBP- 51) (54 kDa progesterone receptor-associated immunophilin) (FKBP54) (P54) (FF1 antigen) (HSP90-binding immunophilin) (Androgen-regulated protein 6).

FKBP4_HUMAN
NC score	0.248508 (rank : 46)	θ value	0.62314 (rank : 98)
Query Neighborhood Hits	277	Target Neighborhood Hits	114	Shared Neighborhood Hits	56
SwissProt Accessions	Q02790, Q9UCP1, Q9UCV7	Gene names	FKBP4
Domain Architecture
Description	FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (p59 protein) (HSP-binding immunophilin) (HBI) (FKBP52 protein) (52 kDa FK506-binding protein) (FKBP59).

FKBP8_MOUSE
NC score	0.242573 (rank : 47)	θ value	4.03905 (rank : 201)
Query Neighborhood Hits	277	Target Neighborhood Hits	94	Shared Neighborhood Hits	51
SwissProt Accessions	O35465, Q99L93	Gene names	Fkbp8, Fkbp38, Sam11
Domain Architecture
Description	38 kDa FK506-binding protein homolog (FKBPR38) (FK506-binding protein 8) (muFKBP38).

FKBP5_MOUSE
NC score	0.241020 (rank : 48)	θ value	1.06291 (rank : 123)
Query Neighborhood Hits	277	Target Neighborhood Hits	97	Shared Neighborhood Hits	50
SwissProt Accessions	Q64378	Gene names	Fkbp5, Fkbp51
Domain Architecture
Description	FK506-binding protein 5 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (51 kDa FK506-binding protein) (FKBP- 51).

FKBP4_MOUSE
NC score	0.232969 (rank : 49)	θ value	1.06291 (rank : 122)
Query Neighborhood Hits	277	Target Neighborhood Hits	100	Shared Neighborhood Hits	49
SwissProt Accessions	P30416, Q3TVC9	Gene names	Fkbp4
Domain Architecture
Description	FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (p59 protein) (HSP-binding immunophilin) (HBI) (FKBP52 protein) (52 kDa FK506-binding protein) (FKBP59).

TTC16_MOUSE
NC score	0.226131 (rank : 50)	θ value	1.81305 (rank : 160)
Query Neighborhood Hits	277	Target Neighborhood Hits	98	Shared Neighborhood Hits	49
SwissProt Accessions	Q8C1F5	Gene names	Ttc16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

FKBP8_HUMAN
NC score	0.222966 (rank : 51)	θ value	6.88961 (rank : 239)
Query Neighborhood Hits	277	Target Neighborhood Hits	85	Shared Neighborhood Hits	44
SwissProt Accessions	Q14318	Gene names	FKBP8, FKBP38
Domain Architecture
Description	38 kDa FK506-binding protein homolog (FKBPR38) (FK506-binding protein 8).

NDUS5_HUMAN
NC score	0.215466 (rank : 52)	θ value	0.0252991 (rank : 38)
Query Neighborhood Hits	277	Target Neighborhood Hits	6	Shared Neighborhood Hits	6
SwissProt Accessions	O43920	Gene names	NDUFS5
Domain Architecture	No domain graphic available
Description	NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 (EC 1.6.5.3) (EC 1.6.99.3) (NADH-ubiquinone oxidoreductase 15 kDa subunit) (Complex I-15 kDa) (CI-15 kDa).

PTMA_HUMAN
NC score	0.205474 (rank : 53)	θ value	0.163984 (rank : 65)
Query Neighborhood Hits	277	Target Neighborhood Hits	88	Shared Neighborhood Hits	20
SwissProt Accessions	P06454, Q15249, Q15592	Gene names	PTMA, TMSA
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha-1].

TTC16_HUMAN
NC score	0.205111 (rank : 54)	θ value	0.125558 (rank : 56)
Query Neighborhood Hits	277	Target Neighborhood Hits	417	Shared Neighborhood Hits	79
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

Z3H7B_HUMAN
NC score	0.203719 (rank : 55)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	277	Target Neighborhood Hits	109	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UGR2, Q5TFX9, Q8TBT9, Q9H8B6, Q9UGQ9, Q9UGR0, Q9UGR1, Q9UK03, Q9UPW9	Gene names	ZC3H7B, KIAA1031
Domain Architecture
Description	Zinc finger CCCH-type domain-containing protein 7B (Rotavirus 'X'- associated non-structural protein) (RoXaN).

BBS4_MOUSE
NC score	0.200055 (rank : 56)	θ value	0.813845 (rank : 105)
Query Neighborhood Hits	277	Target Neighborhood Hits	95	Shared Neighborhood Hits	50
SwissProt Accessions	Q8C1Z7, Q3UYF0, Q8CA57	Gene names	Bbs4
Domain Architecture
Description	Bardet-Biedl syndrome 4 protein homolog.

BBS4_HUMAN
NC score	0.193278 (rank : 57)	θ value	1.81305 (rank : 148)
Query Neighborhood Hits	277	Target Neighborhood Hits	109	Shared Neighborhood Hits	52
SwissProt Accessions	Q96RK4, Q8NHU9, Q96H45	Gene names	BBS4
Domain Architecture
Description	Bardet-Biedl syndrome 4 protein.

PTMA_MOUSE
NC score	0.172082 (rank : 58)	θ value	0.365318 (rank : 87)
Query Neighborhood Hits	277	Target Neighborhood Hits	73	Shared Neighborhood Hits	16
SwissProt Accessions	P26350, Q3UQV6	Gene names	Ptma
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha].

TTC3_HUMAN
NC score	0.171767 (rank : 59)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	277	Target Neighborhood Hits	664	Shared Neighborhood Hits	73
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

TTC14_HUMAN
NC score	0.166987 (rank : 60)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	277	Target Neighborhood Hits	274	Shared Neighborhood Hits	59
SwissProt Accessions	Q96N46, Q6UWJ7, Q8TF22	Gene names	TTC14, KIAA1980
Domain Architecture
Description	Tetratricopeptide repeat protein 14 (TPR repeat protein 14).

K0372_HUMAN
NC score	0.163124 (rank : 61)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	277	Target Neighborhood Hits	136	Shared Neighborhood Hits	53
SwissProt Accessions	Q6PGP7, O15077, Q6PJI3	Gene names	KIAA0372
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein KIAA0372 (TPR repeat protein KIAA0372).

PEX5_MOUSE
NC score	0.161264 (rank : 62)	θ value	1.38821 (rank : 143)
Query Neighborhood Hits	277	Target Neighborhood Hits	89	Shared Neighborhood Hits	39
SwissProt Accessions	O09012	Gene names	Pex5, Pxr1
Domain Architecture
Description	Peroxisomal targeting signal 1 receptor (Peroxisome receptor 1) (Peroxisomal C-terminal targeting signal import receptor) (PTS1-BP) (Peroxin-5) (PTS1 receptor) (PXR1P) (PTS1R).

Z3H7A_HUMAN
NC score	0.161174 (rank : 63)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	277	Target Neighborhood Hits	105	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IWR0, Q9NPE9	Gene names	ZC3H7A, ZC3H7, ZC3HDC7
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH-type domain-containing protein 7A.

CDC23_HUMAN
NC score	0.160178 (rank : 64)	θ value	0.0193708 (rank : 36)
Query Neighborhood Hits	277	Target Neighborhood Hits	69	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UJX2, O75433, Q9BS73	Gene names	CDC23
Domain Architecture
Description	Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8).

PEX5_HUMAN
NC score	0.159439 (rank : 65)	θ value	0.813845 (rank : 114)
Query Neighborhood Hits	277	Target Neighborhood Hits	92	Shared Neighborhood Hits	36
SwissProt Accessions	P50542, Q15115, Q15266	Gene names	PEX5, PXR1
Domain Architecture
Description	Peroxisomal targeting signal 1 receptor (Peroxisome receptor 1) (Peroxisomal C-terminal targeting signal import receptor) (PTS1-BP) (Peroxin-5) (PTS1 receptor).

NSBP1_MOUSE
NC score	0.155712 (rank : 66)	θ value	0.21417 (rank : 70)
Query Neighborhood Hits	277	Target Neighborhood Hits	681	Shared Neighborhood Hits	128
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

PTMS_MOUSE
NC score	0.148494 (rank : 67)	θ value	2.36792 (rank : 176)
Query Neighborhood Hits	277	Target Neighborhood Hits	68	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D0J8	Gene names	Ptms
Domain Architecture	No domain graphic available
Description	Parathymosin.

NASP_HUMAN
NC score	0.145501 (rank : 68)	θ value	0.47712 (rank : 92)
Query Neighborhood Hits	277	Target Neighborhood Hits	709	Shared Neighborhood Hits	125
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

PPID_HUMAN
NC score	0.144352 (rank : 69)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	277	Target Neighborhood Hits	92	Shared Neighborhood Hits	47
SwissProt Accessions	Q08752	Gene names	PPID, CYP40, CYPD
Domain Architecture
Description	40 kDa peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-40) (CYP-40) (Cyclophilin-related protein).

CDC23_MOUSE
NC score	0.137061 (rank : 70)	θ value	0.365318 (rank : 83)
Query Neighborhood Hits	277	Target Neighborhood Hits	65	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BGZ4, Q8C0F1	Gene names	Cdc23
Domain Architecture
Description	Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8).

PEX5R_MOUSE
NC score	0.135121 (rank : 71)	θ value	1.38821 (rank : 142)
Query Neighborhood Hits	277	Target Neighborhood Hits	80	Shared Neighborhood Hits	31
SwissProt Accessions	Q8C437, Q8CA31, Q9DAA1, Q9JMB9	Gene names	Pex5l, Pex2, Pex5r, Pxr2
Domain Architecture
Description	PEX5-related protein (Peroxin-5-related protein) (Pex5Rp) (PEX5-like protein) (PEX2-related protein).

PPID_MOUSE
NC score	0.134724 (rank : 72)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	277	Target Neighborhood Hits	98	Shared Neighborhood Hits	46
SwissProt Accessions	Q9CR16, Q543G1	Gene names	Ppid
Domain Architecture
Description	40 kDa peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-40) (CYP-40).

PEX5R_HUMAN
NC score	0.133804 (rank : 73)	θ value	1.38821 (rank : 141)
Query Neighborhood Hits	277	Target Neighborhood Hits	102	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IYB4, Q9NQD1, Q9P2U3, Q9P2U4	Gene names	PEX5L, PEX5R, PXR2
Domain Architecture
Description	PEX5-related protein (Peroxin-5-related protein) (Pex5Rp) (PEX5-like protein) (PEX2-related protein).

LEO1_HUMAN
NC score	0.132120 (rank : 74)	θ value	1.06291 (rank : 127)
Query Neighborhood Hits	277	Target Neighborhood Hits	958	Shared Neighborhood Hits	146
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

AIPL1_HUMAN
NC score	0.130701 (rank : 75)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	277	Target Neighborhood Hits	113	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NZN9, Q9H873, Q9NS10	Gene names	AIPL1
Domain Architecture
Description	Aryl-hydrocarbon-interacting protein-like 1.

AIPL1_MOUSE
NC score	0.123834 (rank : 76)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	277	Target Neighborhood Hits	45	Shared Neighborhood Hits	30
SwissProt Accessions	Q924K1	Gene names	Aipl1
Domain Architecture
Description	Aryl-hydrocarbon-interacting protein-like 1.

IFT88_HUMAN
NC score	0.120734 (rank : 77)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	277	Target Neighborhood Hits	122	Shared Neighborhood Hits	42
SwissProt Accessions	Q13099	Gene names	IFT88, TG737, TTC10
Domain Architecture
Description	Intraflagellar transport 88 homolog (Tetratricopeptide repeat protein 10) (TPR repeat protein 10) (Recessive polycystic kidney disease protein Tg737 homolog).

NDUS5_MOUSE
NC score	0.118901 (rank : 78)	θ value	1.06291 (rank : 128)
Query Neighborhood Hits	277	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	Q99LY9	Gene names	Ndufs5
Domain Architecture	No domain graphic available
Description	NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 (EC 1.6.5.3) (EC 1.6.99.3) (NADH-ubiquinone oxidoreductase 15 kDa subunit) (Complex I-15 kDa) (CI-15 kDa).

IWS1_MOUSE
NC score	0.118797 (rank : 79)	θ value	0.365318 (rank : 86)
Query Neighborhood Hits	277	Target Neighborhood Hits	1258	Shared Neighborhood Hits	155
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

UBDC1_HUMAN
NC score	0.115523 (rank : 80)	θ value	0.125558 (rank : 57)
Query Neighborhood Hits	277	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BSL1, O75500, Q9UMW7	Gene names	UBADC1, GBDR1, KPC2
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated domain-containing protein 1 (E3 ubiquitin-protein ligase subunit KPC2) (Kip1 ubiquitination-promoting complex protein 2) (Glialblastoma cell differentiation-related protein 1).

UBDC1_MOUSE
NC score	0.115404 (rank : 81)	θ value	0.125558 (rank : 58)
Query Neighborhood Hits	277	Target Neighborhood Hits	29	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VDI7, Q3TZH3	Gene names	Ubadc1, Kpc2
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated domain-containing protein 1 (E3 ubiquitin-protein ligase subunit KPC2) (Kip1 ubiquitination-promoting complex protein 2).

TF3C3_HUMAN
NC score	0.115024 (rank : 82)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	277	Target Neighborhood Hits	90	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y5Q9, Q86XJ8, Q8WX84, Q96B44, Q9H5I8, Q9NT97	Gene names	GTF3C3
Domain Architecture
Description	General transcription factor 3C polypeptide 3 (Transcription factor IIIC-subunit gamma) (TF3C-gamma) (TFIIIC 102 kDa subunit) (TFIIIC102).

IFT88_MOUSE
NC score	0.114568 (rank : 83)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	277	Target Neighborhood Hits	124	Shared Neighborhood Hits	41
SwissProt Accessions	Q61371	Gene names	Ift88, Tg737, Tg737Rpw, TgN737Rpw, Ttc10
Domain Architecture
Description	Intraflagellar transport 88 homolog (Tetratricopeptide repeat protein 10) (TPR repeat protein 10) (Recessive polycystic kidney disease protein Tg737) (TgN(Imorpk)737Rpw).

AIP_HUMAN
NC score	0.114545 (rank : 84)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	277	Target Neighborhood Hits	51	Shared Neighborhood Hits	31
SwissProt Accessions	O00170, Q99606	Gene names	AIP, XAP2
Domain Architecture
Description	AH receptor-interacting protein (AIP) (Aryl-hydrocarbon receptor- interacting protein) (Immunophilin homolog ARA9) (HBV-X-associated protein 2).

LEO1_MOUSE
NC score	0.114442 (rank : 85)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	277	Target Neighborhood Hits	946	Shared Neighborhood Hits	143
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

AIP_MOUSE
NC score	0.112631 (rank : 86)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	277	Target Neighborhood Hits	51	Shared Neighborhood Hits	32
SwissProt Accessions	O08915	Gene names	Aip
Domain Architecture
Description	AH receptor-interacting protein (AIP) (Aryl-hydrocarbon receptor- interacting protein).

PELP1_MOUSE
NC score	0.109492 (rank : 87)	θ value	0.0431538 (rank : 42)
Query Neighborhood Hits	277	Target Neighborhood Hits	709	Shared Neighborhood Hits	46
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

HAP28_HUMAN
NC score	0.108904 (rank : 88)	θ value	0.21417 (rank : 68)
Query Neighborhood Hits	277	Target Neighborhood Hits	57	Shared Neighborhood Hits	13
SwissProt Accessions	Q13442, Q92906	Gene names	PDAP1, HASPP28
Domain Architecture	No domain graphic available
Description	28 kDa heat- and acid-stable phosphoprotein (PDGF-associated protein) (PAP) (PDGFA-associated protein 1) (PAP1).

ERIC1_HUMAN
NC score	0.108156 (rank : 89)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	277	Target Neighborhood Hits	364	Shared Neighborhood Hits	93
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

RENT2_HUMAN
NC score	0.106278 (rank : 90)	θ value	0.0736092 (rank : 48)
Query Neighborhood Hits	277	Target Neighborhood Hits	618	Shared Neighborhood Hits	58
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

YTDC1_HUMAN
NC score	0.105084 (rank : 91)	θ value	0.279714 (rank : 81)
Query Neighborhood Hits	277	Target Neighborhood Hits	458	Shared Neighborhood Hits	63
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

PELP1_HUMAN
NC score	0.102907 (rank : 92)	θ value	0.163984 (rank : 64)
Query Neighborhood Hits	277	Target Neighborhood Hits	596	Shared Neighborhood Hits	39
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

TCAL5_HUMAN
NC score	0.102417 (rank : 93)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	277	Target Neighborhood Hits	806	Shared Neighborhood Hits	138
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

IWS1_HUMAN
NC score	0.099744 (rank : 94)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	277	Target Neighborhood Hits	1241	Shared Neighborhood Hits	144
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

RPGR1_MOUSE
NC score	0.099713 (rank : 95)	θ value	0.0252991 (rank : 39)
Query Neighborhood Hits	277	Target Neighborhood Hits	713	Shared Neighborhood Hits	59
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

SMRC2_HUMAN
NC score	0.097609 (rank : 96)	θ value	0.0961366 (rank : 52)
Query Neighborhood Hits	277	Target Neighborhood Hits	499	Shared Neighborhood Hits	68
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

AKA12_HUMAN
NC score	0.097300 (rank : 97)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	277	Target Neighborhood Hits	825	Shared Neighborhood Hits	133
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

MDN1_HUMAN
NC score	0.090353 (rank : 98)	θ value	1.38821 (rank : 139)
Query Neighborhood Hits	277	Target Neighborhood Hits	662	Shared Neighborhood Hits	106
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

SMRC2_MOUSE
NC score	0.089792 (rank : 99)	θ value	0.279714 (rank : 77)
Query Neighborhood Hits	277	Target Neighborhood Hits	487	Shared Neighborhood Hits	68
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

UBF1_HUMAN
NC score	0.088075 (rank : 100)	θ value	0.125558 (rank : 59)
Query Neighborhood Hits	277	Target Neighborhood Hits	415	Shared Neighborhood Hits	48
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

CENPB_MOUSE
NC score	0.085951 (rank : 101)	θ value	0.365318 (rank : 84)
Query Neighborhood Hits	277	Target Neighborhood Hits	163	Shared Neighborhood Hits	23
SwissProt Accessions	P27790	Gene names	Cenpb, Cenp-b
Domain Architecture
Description	Major centromere autoantigen B (Centromere protein B) (CENP-B).

NCOR2_HUMAN
NC score	0.085869 (rank : 102)	θ value	0.0961366 (rank : 51)
Query Neighborhood Hits	277	Target Neighborhood Hits	870	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

NCOR2_MOUSE
NC score	0.085797 (rank : 103)	θ value	0.125558 (rank : 54)
Query Neighborhood Hits	277	Target Neighborhood Hits	790	Shared Neighborhood Hits	55
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

TRI44_HUMAN
NC score	0.085322 (rank : 104)	θ value	0.163984 (rank : 66)
Query Neighborhood Hits	277	Target Neighborhood Hits	393	Shared Neighborhood Hits	30
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

CTR9_MOUSE
NC score	0.083917 (rank : 105)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	277	Target Neighborhood Hits	427	Shared Neighborhood Hits	67
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

CTR9_HUMAN
NC score	0.083303 (rank : 106)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	277	Target Neighborhood Hits	383	Shared Neighborhood Hits	63
SwissProt Accessions	Q6PD62, Q15015	Gene names	CTR9, KIAA0155, SH2BP1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1).

UBF1_MOUSE
NC score	0.082774 (rank : 107)	θ value	0.47712 (rank : 96)
Query Neighborhood Hits	277	Target Neighborhood Hits	419	Shared Neighborhood Hits	45
SwissProt Accessions	P25976	Gene names	Ubtf, Tcfubf, Ubf-1, Ubf1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1).

PP2CG_HUMAN
NC score	0.081607 (rank : 108)	θ value	0.0736092 (rank : 47)
Query Neighborhood Hits	277	Target Neighborhood Hits	140	Shared Neighborhood Hits	18
SwissProt Accessions	O15355	Gene names	PPM1G, PPM1C
Domain Architecture
Description	Protein phosphatase 2C isoform gamma (EC 3.1.3.16) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C).

SEC63_MOUSE
NC score	0.080538 (rank : 109)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	277	Target Neighborhood Hits	601	Shared Neighborhood Hits	118
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

SMYD4_MOUSE
NC score	0.080260 (rank : 110)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	277	Target Neighborhood Hits	85	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BTK5, Q3U3Z8, Q501N5, Q5SWN4, Q69Z60, Q8BMP3	Gene names	Smyd4, Kiaa1936
Domain Architecture	No domain graphic available
Description	SET and MYND domain-containing protein 4.

APC7_HUMAN
NC score	0.079876 (rank : 111)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	277	Target Neighborhood Hits	57	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UJX3, Q96AC4, Q96GF4, Q9BU24, Q9NT16	Gene names	ANAPC7, APC7
Domain Architecture
Description	Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7).

DAXX_HUMAN
NC score	0.079290 (rank : 112)	θ value	0.47712 (rank : 91)
Query Neighborhood Hits	277	Target Neighborhood Hits	207	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UER7, O14747, O15141, O15208, Q9BWI3	Gene names	DAXX, BING2, DAP6
Domain Architecture
Description	Death domain-associated protein 6 (Daxx) (hDaxx) (Fas death domain- associated protein) (ETS1-associated protein 1) (EAP1).

NCOR1_MOUSE
NC score	0.078617 (rank : 113)	θ value	0.279714 (rank : 76)
Query Neighborhood Hits	277	Target Neighborhood Hits	521	Shared Neighborhood Hits	44
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

APC7_MOUSE
NC score	0.078480 (rank : 114)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	277	Target Neighborhood Hits	56	Shared Neighborhood Hits	27
SwissProt Accessions	Q9WVM3, Q3UBM7, Q8BSR2, Q91W13	Gene names	Anapc7, Apc7
Domain Architecture
Description	Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7) (Prediabetic NOD sera-reactive autoantigen).

SPRL1_MOUSE
NC score	0.077407 (rank : 115)	θ value	1.38821 (rank : 145)
Query Neighborhood Hits	277	Target Neighborhood Hits	403	Shared Neighborhood Hits	86
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

SEC63_HUMAN
NC score	0.077005 (rank : 116)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	277	Target Neighborhood Hits	586	Shared Neighborhood Hits	118
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

AP3B1_HUMAN
NC score	0.076747 (rank : 117)	θ value	0.0330416 (rank : 40)
Query Neighborhood Hits	277	Target Neighborhood Hits	283	Shared Neighborhood Hits	28
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

TGON1_MOUSE
NC score	0.075713 (rank : 118)	θ value	0.279714 (rank : 79)
Query Neighborhood Hits	277	Target Neighborhood Hits	243	Shared Neighborhood Hits	33
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

CENPB_HUMAN
NC score	0.074950 (rank : 119)	θ value	2.36792 (rank : 163)
Query Neighborhood Hits	277	Target Neighborhood Hits	133	Shared Neighborhood Hits	22
SwissProt Accessions	P07199	Gene names	CENPB
Domain Architecture
Description	Major centromere autoantigen B (Centromere protein B) (CENP-B).

SMYD4_HUMAN
NC score	0.074697 (rank : 120)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	277	Target Neighborhood Hits	81	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IYR2, Q8N1P2, Q8NAT0, Q96LV4, Q96PV2	Gene names	SMYD4, KIAA1936
Domain Architecture	No domain graphic available
Description	SET and MYND domain-containing protein 4.

AP3B1_MOUSE
NC score	0.073583 (rank : 121)	θ value	0.0563607 (rank : 44)
Query Neighborhood Hits	277	Target Neighborhood Hits	302	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

TRI44_MOUSE
NC score	0.072521 (rank : 122)	θ value	1.06291 (rank : 132)
Query Neighborhood Hits	277	Target Neighborhood Hits	327	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

CYLC1_HUMAN
NC score	0.072496 (rank : 123)	θ value	1.38821 (rank : 136)
Query Neighborhood Hits	277	Target Neighborhood Hits	408	Shared Neighborhood Hits	45
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

IFIT3_HUMAN
NC score	0.072298 (rank : 124)	θ value	8.99809 (rank : 265)
Query Neighborhood Hits	277	Target Neighborhood Hits	83	Shared Neighborhood Hits	30
SwissProt Accessions	O14879, Q99634, Q9BSK7	Gene names	IFIT3, IFI60, IFIT4
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 3 (IFIT-3) (IFIT-4) (Interferon-induced 60 kDa protein) (IFI-60K) (ISG-60) (CIG49) (Retinoic acid-induced gene G protein) (RIG-G).

SFR12_MOUSE
NC score	0.071864 (rank : 125)	θ value	0.47712 (rank : 95)
Query Neighborhood Hits	277	Target Neighborhood Hits	486	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

SMRC1_MOUSE
NC score	0.071540 (rank : 126)	θ value	8.99809 (rank : 271)
Query Neighborhood Hits	277	Target Neighborhood Hits	459	Shared Neighborhood Hits	78
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

DNJC8_MOUSE
NC score	0.071335 (rank : 127)	θ value	2.36792 (rank : 169)
Query Neighborhood Hits	277	Target Neighborhood Hits	392	Shared Neighborhood Hits	53
SwissProt Accessions	Q6NZB0, Q6PG72, Q8C2M6	Gene names	Dnajc8
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 8.

TNNT3_MOUSE
NC score	0.070842 (rank : 128)	θ value	0.125558 (rank : 55)
Query Neighborhood Hits	277	Target Neighborhood Hits	317	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QZ47, O35575, O35576, O35577, O35578, O35579, O35580, O35581, O35582, O35583, O35584, O35585, P97456, Q99L89, Q9QZ46	Gene names	Tnnt3
Domain Architecture	No domain graphic available
Description	Troponin T, fast skeletal muscle (TnTf) (Fast skeletal muscle troponin T) (fTnT).

CP053_HUMAN
NC score	0.070637 (rank : 129)	θ value	2.36792 (rank : 165)
Query Neighborhood Hits	277	Target Neighborhood Hits	45	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BTK6	Gene names	C16orf53
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf53.

BAZ1A_HUMAN
NC score	0.070617 (rank : 130)	θ value	0.21417 (rank : 67)
Query Neighborhood Hits	277	Target Neighborhood Hits	693	Shared Neighborhood Hits	68
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

DNJC8_HUMAN
NC score	0.069947 (rank : 131)	θ value	2.36792 (rank : 168)
Query Neighborhood Hits	277	Target Neighborhood Hits	380	Shared Neighborhood Hits	50
SwissProt Accessions	O75937, Q6IBA4, Q8N4Z5, Q9P051, Q9P067	Gene names	DNAJC8, SPF31
Domain Architecture
Description	DnaJ homolog subfamily C member 8 (Splicing protein spf31).

MYT1_HUMAN
NC score	0.069019 (rank : 132)	θ value	0.0736092 (rank : 46)
Query Neighborhood Hits	277	Target Neighborhood Hits	475	Shared Neighborhood Hits	51
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

TXND2_MOUSE
NC score	0.067914 (rank : 133)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	277	Target Neighborhood Hits	828	Shared Neighborhood Hits	118
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

HTSF1_MOUSE
NC score	0.066922 (rank : 134)	θ value	2.36792 (rank : 172)
Query Neighborhood Hits	277	Target Neighborhood Hits	425	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

SETD2_HUMAN
NC score	0.066667 (rank : 135)	θ value	0.0736092 (rank : 49)
Query Neighborhood Hits	277	Target Neighborhood Hits	412	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

DAXX_MOUSE
NC score	0.066607 (rank : 136)	θ value	3.0926 (rank : 185)
Query Neighborhood Hits	277	Target Neighborhood Hits	173	Shared Neighborhood Hits	20
SwissProt Accessions	O35613, Q9QWT8, Q9QWV3	Gene names	Daxx
Domain Architecture
Description	Death domain-associated protein 6 (Daxx).

BAZ2B_HUMAN
NC score	0.064916 (rank : 137)	θ value	0.365318 (rank : 82)
Query Neighborhood Hits	277	Target Neighborhood Hits	803	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

CDC37_HUMAN
NC score	0.063937 (rank : 138)	θ value	1.81305 (rank : 150)
Query Neighborhood Hits	277	Target Neighborhood Hits	506	Shared Neighborhood Hits	58
SwissProt Accessions	Q16543	Gene names	CDC37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

HAP28_MOUSE
NC score	0.063652 (rank : 139)	θ value	4.03905 (rank : 202)
Query Neighborhood Hits	277	Target Neighborhood Hits	50	Shared Neighborhood Hits	11
SwissProt Accessions	Q3UHX2, Q3KQJ5	Gene names	Pdap1
Domain Architecture	No domain graphic available
Description	28 kDa heat- and acid-stable phosphoprotein (PDGF-associated protein) (PAP) (PDGFA-associated protein 1) (PAP1).

ADNP_MOUSE
NC score	0.061879 (rank : 140)	θ value	0.47712 (rank : 89)
Query Neighborhood Hits	277	Target Neighborhood Hits	232	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z103	Gene names	Adnp
Domain Architecture
Description	Activity-dependent neuroprotector (Activity-dependent neuroprotective protein).

RPGR_MOUSE
NC score	0.061717 (rank : 141)	θ value	0.365318 (rank : 88)
Query Neighborhood Hits	277	Target Neighborhood Hits	281	Shared Neighborhood Hits	72
SwissProt Accessions	Q9R0X5, O88408, Q9CU92	Gene names	Rpgr
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator (mRpgr).

ATRX_HUMAN
NC score	0.060894 (rank : 142)	θ value	1.81305 (rank : 147)
Query Neighborhood Hits	277	Target Neighborhood Hits	842	Shared Neighborhood Hits	90
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

TGON2_HUMAN
NC score	0.059883 (rank : 143)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	277	Target Neighborhood Hits	1037	Shared Neighborhood Hits	99
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

NIPBL_HUMAN
NC score	0.059700 (rank : 144)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	277	Target Neighborhood Hits	1311	Shared Neighborhood Hits	130
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

VCX3_HUMAN
NC score	0.059495 (rank : 145)	θ value	8.99809 (rank : 276)
Query Neighborhood Hits	277	Target Neighborhood Hits	105	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NNX9, Q9P0H4	Gene names	VCX3A, VCX3, VCX8R, VCXA
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 3 (VCX-A protein) (Variably charged protein X-A) (Variable charge protein on X with eight repeats) (VCX- 8r).

SMRC1_HUMAN
NC score	0.058889 (rank : 146)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	277	Target Neighborhood Hits	375	Shared Neighborhood Hits	57
SwissProt Accessions	Q92922, Q6P172, Q8IWH2	Gene names	SMARCC1, BAF155
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155).

ZN622_HUMAN
NC score	0.058562 (rank : 147)	θ value	1.06291 (rank : 134)
Query Neighborhood Hits	277	Target Neighborhood Hits	62	Shared Neighborhood Hits	9
SwissProt Accessions	Q969S3	Gene names	ZNF622, ZPR9
Domain Architecture	No domain graphic available
Description	Zinc finger protein 622 (Zinc finger-like protein 9).

FKBP6_MOUSE
NC score	0.058495 (rank : 148)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	277	Target Neighborhood Hits	37	Shared Neighborhood Hits	13
SwissProt Accessions	Q91XW8, Q91Y30	Gene names	Fkbp6
Domain Architecture
Description	FK506-binding protein 6 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (36 kDa FK506-binding protein) (FKBP- 36) (Immunophilin FKBP36).

NSBP1_HUMAN
NC score	0.057944 (rank : 149)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	277	Target Neighborhood Hits	251	Shared Neighborhood Hits	31
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

TGON2_MOUSE
NC score	0.057866 (rank : 150)	θ value	2.36792 (rank : 180)
Query Neighborhood Hits	277	Target Neighborhood Hits	277	Shared Neighborhood Hits	36
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

TCAL3_HUMAN
NC score	0.057822 (rank : 151)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	277	Target Neighborhood Hits	274	Shared Neighborhood Hits	78
SwissProt Accessions	Q969E4	Gene names	TCEAL3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

VCX1_HUMAN
NC score	0.057000 (rank : 152)	θ value	5.27518 (rank : 230)
Query Neighborhood Hits	277	Target Neighborhood Hits	129	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H320, Q9P0H3	Gene names	VCX, VCX1, VCX10R, VCXB1
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 1 (VCX-B1 protein) (Variably charged protein X-B1) (Variable charge protein on X with ten repeats) (VCX- 10r).

NUCL_HUMAN
NC score	0.056804 (rank : 153)	θ value	0.21417 (rank : 71)
Query Neighborhood Hits	277	Target Neighborhood Hits	415	Shared Neighborhood Hits	30
SwissProt Accessions	P19338, Q53SK1, Q8NB06	Gene names	NCL
Domain Architecture
Description	Nucleolin (Protein C23).

ATRX_MOUSE
NC score	0.056734 (rank : 154)	θ value	0.813845 (rank : 104)
Query Neighborhood Hits	277	Target Neighborhood Hits	682	Shared Neighborhood Hits	68
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

ZC313_HUMAN
NC score	0.056261 (rank : 155)	θ value	8.99809 (rank : 277)
Query Neighborhood Hits	277	Target Neighborhood Hits	772	Shared Neighborhood Hits	95
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

HTSF1_HUMAN
NC score	0.056057 (rank : 156)	θ value	5.27518 (rank : 214)
Query Neighborhood Hits	277	Target Neighborhood Hits	408	Shared Neighborhood Hits	37
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

T2FA_HUMAN
NC score	0.055973 (rank : 157)	θ value	5.27518 (rank : 227)
Query Neighborhood Hits	277	Target Neighborhood Hits	228	Shared Neighborhood Hits	21
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

ABTAP_MOUSE
NC score	0.055846 (rank : 158)	θ value	1.81305 (rank : 146)
Query Neighborhood Hits	277	Target Neighborhood Hits	381	Shared Neighborhood Hits	37
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

NCOR1_HUMAN
NC score	0.055463 (rank : 159)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	277	Target Neighborhood Hits	577	Shared Neighborhood Hits	61
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

ASPH_HUMAN
NC score	0.055454 (rank : 160)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	277	Target Neighborhood Hits	158	Shared Neighborhood Hits	52
SwissProt Accessions	Q12797	Gene names	ASPH
Domain Architecture
Description	Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16) (Aspartate beta- hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta- dioxygenase).

TCAL3_MOUSE
NC score	0.055424 (rank : 161)	θ value	0.813845 (rank : 116)
Query Neighborhood Hits	277	Target Neighborhood Hits	132	Shared Neighborhood Hits	28
SwissProt Accessions	Q8R0A5, Q9CYK5, Q9D1S4	Gene names	Tceal3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

MYST4_HUMAN
NC score	0.055190 (rank : 162)	θ value	1.81305 (rank : 157)
Query Neighborhood Hits	277	Target Neighborhood Hits	671	Shared Neighborhood Hits	85
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

PP2CG_MOUSE
NC score	0.055182 (rank : 163)	θ value	1.81305 (rank : 159)
Query Neighborhood Hits	277	Target Neighborhood Hits	185	Shared Neighborhood Hits	16
SwissProt Accessions	Q61074	Gene names	Ppm1g, Fin13, Ppm1c
Domain Architecture
Description	Protein phosphatase 2C isoform gamma (EC 3.1.3.16) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C) (Fibroblast growth factor-inducible protein 13) (FIN13).

DMP1_HUMAN
NC score	0.054905 (rank : 164)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	277	Target Neighborhood Hits	491	Shared Neighborhood Hits	77
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

PTMS_HUMAN
NC score	0.054431 (rank : 165)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	277	Target Neighborhood Hits	111	Shared Neighborhood Hits	17
SwissProt Accessions	P20962	Gene names	PTMS
Domain Architecture	No domain graphic available
Description	Parathymosin.

RRMJ3_MOUSE
NC score	0.054312 (rank : 166)	θ value	0.47712 (rank : 94)
Query Neighborhood Hits	277	Target Neighborhood Hits	163	Shared Neighborhood Hits	14
SwissProt Accessions	Q9DBE9, Q3ULI1, Q921I7	Gene names	Ftsj3
Domain Architecture	No domain graphic available
Description	Putative rRNA methyltransferase 3 (EC 2.1.1.-) (rRNA (uridine-2'-O-)- methyltransferase 3).

CC47_MOUSE
NC score	0.054098 (rank : 167)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	277	Target Neighborhood Hits	245	Shared Neighborhood Hits	74
SwissProt Accessions	Q9D024, Q3TSB5, Q3V1S7, Q8C5D9, Q920S6	Gene names	Ccdc47, Asp4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor (Adipocyte-specific protein 4).

CALR_MOUSE
NC score	0.054080 (rank : 168)	θ value	0.47712 (rank : 90)
Query Neighborhood Hits	277	Target Neighborhood Hits	68	Shared Neighborhood Hits	12
SwissProt Accessions	P14211	Gene names	Calr
Domain Architecture
Description	Calreticulin precursor (CRP55) (Calregulin) (HACBP) (ERp60).

RP1L1_HUMAN
NC score	0.054040 (rank : 169)	θ value	0.813845 (rank : 115)
Query Neighborhood Hits	277	Target Neighborhood Hits	1072	Shared Neighborhood Hits	72
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

CP053_MOUSE
NC score	0.053808 (rank : 170)	θ value	5.27518 (rank : 210)
Query Neighborhood Hits	277	Target Neighborhood Hits	38	Shared Neighborhood Hits	8
SwissProt Accessions	Q99L02	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf53 homolog.

TTC28_MOUSE
NC score	0.053643 (rank : 171)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	277	Target Neighborhood Hits	194	Shared Neighborhood Hits	31
SwissProt Accessions	Q80XJ3, Q6P9J6, Q80TL5, Q8BV10, Q8C0F2	Gene names	Ttc28, Kiaa1043
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

TTC28_HUMAN
NC score	0.053504 (rank : 172)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	277	Target Neighborhood Hits	271	Shared Neighborhood Hits	38
SwissProt Accessions	Q96AY4, O95928, O95929, Q9NTE4, Q9UG31, Q9UGG5, Q9UPV8, Q9Y3S5	Gene names	TTC28, KIAA1043
Domain Architecture
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

CRNL1_HUMAN
NC score	0.052794 (rank : 173)	θ value	0.62314 (rank : 97)
Query Neighborhood Hits	277	Target Neighborhood Hits	76	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BZJ0, Q5JY64, Q8WYI5, Q9BZI9, Q9BZJ1, Q9BZJ2, Q9GZW7, Q9H8F8, Q9NQH5, Q9NYD8	Gene names	CRNKL1, CRN
Domain Architecture
Description	Crooked neck-like protein 1 (Crooked neck homolog) (hCrn).

BAZ1B_HUMAN
NC score	0.052709 (rank : 174)	θ value	2.36792 (rank : 162)
Query Neighborhood Hits	277	Target Neighborhood Hits	701	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

SFR12_HUMAN
NC score	0.052586 (rank : 175)	θ value	5.27518 (rank : 224)
Query Neighborhood Hits	277	Target Neighborhood Hits	553	Shared Neighborhood Hits	50
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

VPS72_MOUSE
NC score	0.052421 (rank : 176)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	277	Target Neighborhood Hits	286	Shared Neighborhood Hits	76
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

NPBL_MOUSE
NC score	0.051905 (rank : 177)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	277	Target Neighborhood Hits	1041	Shared Neighborhood Hits	107
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

CLSPN_HUMAN
NC score	0.051734 (rank : 178)	θ value	2.36792 (rank : 164)
Query Neighborhood Hits	277	Target Neighborhood Hits	433	Shared Neighborhood Hits	51
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

RBBP6_HUMAN
NC score	0.051665 (rank : 179)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	277	Target Neighborhood Hits	1135	Shared Neighborhood Hits	107
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

VPS72_HUMAN
NC score	0.051371 (rank : 180)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	277	Target Neighborhood Hits	274	Shared Neighborhood Hits	74
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

DMP1_MOUSE
NC score	0.050875 (rank : 181)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	277	Target Neighborhood Hits	498	Shared Neighborhood Hits	82
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

TNNT2_HUMAN
NC score	0.050780 (rank : 182)	θ value	4.03905 (rank : 205)
Query Neighborhood Hits	277	Target Neighborhood Hits	433	Shared Neighborhood Hits	35
SwissProt Accessions	P45379, O60214, Q99596, Q99597, Q9UM96	Gene names	TNNT2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

TXND2_HUMAN
NC score	0.050759 (rank : 183)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	277	Target Neighborhood Hits	793	Shared Neighborhood Hits	94
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

VCXC_HUMAN
NC score	0.050455 (rank : 184)	θ value	6.88961 (rank : 251)
Query Neighborhood Hits	277	Target Neighborhood Hits	139	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H321	Gene names	VCXC
Domain Architecture	No domain graphic available
Description	VCX-C protein (Variably charged protein X-C).

IFIT1_MOUSE
NC score	0.050192 (rank : 185)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	277	Target Neighborhood Hits	59	Shared Neighborhood Hits	25
SwissProt Accessions	Q64282	Gene names	Ifit1, Garg16, Ifi56
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 1 (IFIT-1) (Interferon-induced 56 kDa protein) (IFI-56K) (Glucocorticoid- attenuated response gene 16 protein) (GARG-16).

NCF2_HUMAN
NC score	0.048927 (rank : 186)	θ value	5.27518 (rank : 221)
Query Neighborhood Hits	277	Target Neighborhood Hits	229	Shared Neighborhood Hits	15
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

AN32B_MOUSE
NC score	0.048637 (rank : 187)	θ value	1.38821 (rank : 135)
Query Neighborhood Hits	277	Target Neighborhood Hits	236	Shared Neighborhood Hits	23
SwissProt Accessions	Q9EST5	Gene names	Anp32b, Pal31
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member B (Proliferation-related acidic leucine-rich protein PAL31).

NUCL_MOUSE
NC score	0.048286 (rank : 188)	θ value	1.06291 (rank : 130)
Query Neighborhood Hits	277	Target Neighborhood Hits	425	Shared Neighborhood Hits	29
SwissProt Accessions	P09405, Q548M9, Q61991, Q99K50	Gene names	Ncl, Nuc
Domain Architecture
Description	Nucleolin (Protein C23).

GLU2B_MOUSE
NC score	0.048104 (rank : 189)	θ value	0.62314 (rank : 99)
Query Neighborhood Hits	277	Target Neighborhood Hits	357	Shared Neighborhood Hits	31
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

ACINU_MOUSE
NC score	0.048026 (rank : 190)	θ value	5.27518 (rank : 207)
Query Neighborhood Hits	277	Target Neighborhood Hits	712	Shared Neighborhood Hits	69
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

PININ_MOUSE
NC score	0.047728 (rank : 191)	θ value	8.99809 (rank : 268)
Query Neighborhood Hits	277	Target Neighborhood Hits	777	Shared Neighborhood Hits	71
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

MYST3_HUMAN
NC score	0.047424 (rank : 192)	θ value	6.88961 (rank : 243)
Query Neighborhood Hits	277	Target Neighborhood Hits	772	Shared Neighborhood Hits	64
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

CALR_HUMAN
NC score	0.047407 (rank : 193)	θ value	1.06291 (rank : 118)
Query Neighborhood Hits	277	Target Neighborhood Hits	85	Shared Neighborhood Hits	15
SwissProt Accessions	P27797	Gene names	CALR, CRTC
Domain Architecture
Description	Calreticulin precursor (CRP55) (Calregulin) (HACBP) (ERp60) (grp60).

MS3L1_HUMAN
NC score	0.047044 (rank : 194)	θ value	0.813845 (rank : 111)
Query Neighborhood Hits	277	Target Neighborhood Hits	60	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N5Y2, Q9UG70, Q9Y5Z8	Gene names	MSL3L1
Domain Architecture
Description	Male-specific lethal 3-like 1 (MSL3-like 1) (Male-specific lethal-3 homolog 1).

DYNA_HUMAN
NC score	0.045824 (rank : 195)	θ value	0.163984 (rank : 63)
Query Neighborhood Hits	277	Target Neighborhood Hits	1194	Shared Neighborhood Hits	70
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

MYT1L_MOUSE
NC score	0.045767 (rank : 196)	θ value	2.36792 (rank : 174)
Query Neighborhood Hits	277	Target Neighborhood Hits	461	Shared Neighborhood Hits	43
SwissProt Accessions	P97500, O08996, Q8C643, Q8C7L4, Q8CHB4	Gene names	Myt1l, Kiaa1106, Nzf1, Png1
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (Postmitotic neural gene 1 protein) (Zinc finger protein Png-1) (Neural zinc finger factor 1) (NZF-1).

CCDC3_HUMAN
NC score	0.044681 (rank : 197)	θ value	3.0926 (rank : 183)
Query Neighborhood Hits	277	Target Neighborhood Hits	111	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BQI4	Gene names	CCDC3
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 3 precursor.

HTF4_MOUSE
NC score	0.044671 (rank : 198)	θ value	0.279714 (rank : 75)
Query Neighborhood Hits	277	Target Neighborhood Hits	153	Shared Neighborhood Hits	7
SwissProt Accessions	Q61286	Gene names	Tcf12, Alf1, Meb
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4) (Class A helix-loop-helix transcription factor ME1).

TRM6_HUMAN
NC score	0.044637 (rank : 199)	θ value	4.03905 (rank : 206)
Query Neighborhood Hits	277	Target Neighborhood Hits	66	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UJA5, Q76P92, Q9BQV5, Q9ULR7	Gene names	TRM6, KIAA1153
Domain Architecture	No domain graphic available
Description	tRNA (adenine-N(1)-)-methyltransferase non-catalytic subunit TRM6 (tRNA(m1A58)-methyltransferase subunit TRM6) (tRNA(m1A58)MTase subunit TRM6).

NFH_MOUSE
NC score	0.044632 (rank : 200)	θ value	0.813845 (rank : 112)
Query Neighborhood Hits	277	Target Neighborhood Hits	2247	Shared Neighborhood Hits	118
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PININ_HUMAN
NC score	0.044537 (rank : 201)	θ value	8.99809 (rank : 267)
Query Neighborhood Hits	277	Target Neighborhood Hits	753	Shared Neighborhood Hits	76
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

BPTF_HUMAN
NC score	0.044388 (rank : 202)	θ value	8.99809 (rank : 257)
Query Neighborhood Hits	277	Target Neighborhood Hits	786	Shared Neighborhood Hits	79
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

NP1L3_MOUSE
NC score	0.044195 (rank : 203)	θ value	1.38821 (rank : 140)
Query Neighborhood Hits	277	Target Neighborhood Hits	233	Shared Neighborhood Hits	35
SwissProt Accessions	Q794H2, O54802	Gene names	Nap1l3, Mb20
Domain Architecture	No domain graphic available
Description	Nucleosome assembly protein 1-like 3 (Brain-specific protein MB20).

HTF4_HUMAN
NC score	0.043869 (rank : 204)	θ value	0.813845 (rank : 110)
Query Neighborhood Hits	277	Target Neighborhood Hits	152	Shared Neighborhood Hits	8
SwissProt Accessions	Q99081	Gene names	TCF12, HEB, HTF4
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4).

FA44A_HUMAN
NC score	0.043618 (rank : 205)	θ value	1.81305 (rank : 152)
Query Neighborhood Hits	277	Target Neighborhood Hits	280	Shared Neighborhood Hits	39
SwissProt Accessions	Q8NFC6, Q6P0M8	Gene names	FAM44A
Domain Architecture	No domain graphic available
Description	Protein FAM44A.

NRDC_MOUSE
NC score	0.043131 (rank : 206)	θ value	1.06291 (rank : 129)
Query Neighborhood Hits	277	Target Neighborhood Hits	96	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BHG1	Gene names	Nrd1
Domain Architecture
Description	Nardilysin precursor (EC 3.4.24.61) (N-arginine dibasic convertase) (NRD convertase) (NRD-C).

MAP1B_HUMAN
NC score	0.042937 (rank : 207)	θ value	5.27518 (rank : 218)
Query Neighborhood Hits	277	Target Neighborhood Hits	903	Shared Neighborhood Hits	81
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

CALD1_HUMAN
NC score	0.042785 (rank : 208)	θ value	6.88961 (rank : 234)
Query Neighborhood Hits	277	Target Neighborhood Hits	959	Shared Neighborhood Hits	76
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

CBP_MOUSE
NC score	0.042069 (rank : 209)	θ value	0.813845 (rank : 106)
Query Neighborhood Hits	277	Target Neighborhood Hits	1051	Shared Neighborhood Hits	40
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

AN32B_HUMAN
NC score	0.041753 (rank : 210)	θ value	6.88961 (rank : 231)
Query Neighborhood Hits	277	Target Neighborhood Hits	243	Shared Neighborhood Hits	23
SwissProt Accessions	Q92688, O00655, P78458, P78459	Gene names	ANP32B, APRIL, PHAPI2
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member B (PHAPI2 protein) (Silver-stainable protein SSP29) (Acidic protein rich in leucines).

RBBP5_HUMAN
NC score	0.041714 (rank : 211)	θ value	2.36792 (rank : 177)
Query Neighborhood Hits	277	Target Neighborhood Hits	372	Shared Neighborhood Hits	54
SwissProt Accessions	Q15291	Gene names	RBBP5, RBQ3
Domain Architecture
Description	Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3).

CAR10_HUMAN
NC score	0.041237 (rank : 212)	θ value	0.163984 (rank : 61)
Query Neighborhood Hits	277	Target Neighborhood Hits	569	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BWT7, Q14CQ8, Q5TFG6, Q9UGR5, Q9UGR6, Q9Y3H0	Gene names	CARD10, CARMA3
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3).

CBP_HUMAN
NC score	0.041191 (rank : 213)	θ value	1.81305 (rank : 149)
Query Neighborhood Hits	277	Target Neighborhood Hits	941	Shared Neighborhood Hits	37
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

KI21A_HUMAN
NC score	0.041043 (rank : 214)	θ value	1.38821 (rank : 138)
Query Neighborhood Hits	277	Target Neighborhood Hits	1543	Shared Neighborhood Hits	98
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

NFM_MOUSE
NC score	0.040558 (rank : 215)	θ value	0.813845 (rank : 113)
Query Neighborhood Hits	277	Target Neighborhood Hits	1159	Shared Neighborhood Hits	90
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

ARS2_HUMAN
NC score	0.040112 (rank : 216)	θ value	6.88961 (rank : 233)
Query Neighborhood Hits	277	Target Neighborhood Hits	186	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BXP5, O95808, Q9BWP6, Q9BXP4	Gene names	ARS2, ASR2
Domain Architecture
Description	Arsenite-resistance protein 2.

NFH_HUMAN
NC score	0.039992 (rank : 217)	θ value	1.81305 (rank : 158)
Query Neighborhood Hits	277	Target Neighborhood Hits	1242	Shared Neighborhood Hits	80
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

AN32E_HUMAN
NC score	0.039881 (rank : 218)	θ value	6.88961 (rank : 232)
Query Neighborhood Hits	277	Target Neighborhood Hits	291	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BTT0, Q8N1S4, Q8WWW9	Gene names	ANP32E
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member E (LANP- like protein) (LANP-L).

TNNT2_MOUSE
NC score	0.038971 (rank : 219)	θ value	6.88961 (rank : 249)
Query Neighborhood Hits	277	Target Neighborhood Hits	395	Shared Neighborhood Hits	33
SwissProt Accessions	P50752, Q64360, Q64377	Gene names	Tnnt2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

MBB1A_HUMAN
NC score	0.038636 (rank : 220)	θ value	6.88961 (rank : 242)
Query Neighborhood Hits	277	Target Neighborhood Hits	665	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

CENPF_HUMAN
NC score	0.038635 (rank : 221)	θ value	0.163984 (rank : 62)
Query Neighborhood Hits	277	Target Neighborhood Hits	1932	Shared Neighborhood Hits	103
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

NFM_HUMAN
NC score	0.038616 (rank : 222)	θ value	5.27518 (rank : 222)
Query Neighborhood Hits	277	Target Neighborhood Hits	1328	Shared Neighborhood Hits	98
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

HS90A_MOUSE
NC score	0.038122 (rank : 223)	θ value	1.06291 (rank : 126)
Query Neighborhood Hits	277	Target Neighborhood Hits	155	Shared Neighborhood Hits	21
SwissProt Accessions	P07901	Gene names	Hsp90aa1, Hsp86, Hsp86-1, Hspca
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (Tumor-specific transplantation 86 kDa antigen) (TSTA).

SF3B2_HUMAN
NC score	0.037988 (rank : 224)	θ value	3.0926 (rank : 191)
Query Neighborhood Hits	277	Target Neighborhood Hits	157	Shared Neighborhood Hits	18
SwissProt Accessions	Q13435	Gene names	SF3B2, SAP145
Domain Architecture
Description	Splicing factor 3B subunit 2 (Spliceosome-associated protein 145) (SAP 145) (SF3b150) (Pre-mRNA-splicing factor SF3b 145 kDa subunit).

TPR_HUMAN
NC score	0.037383 (rank : 225)	θ value	8.99809 (rank : 275)
Query Neighborhood Hits	277	Target Neighborhood Hits	1921	Shared Neighborhood Hits	123
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

KI21A_MOUSE
NC score	0.037139 (rank : 226)	θ value	1.81305 (rank : 155)
Query Neighborhood Hits	277	Target Neighborhood Hits	1317	Shared Neighborhood Hits	79
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

IFIT2_MOUSE
NC score	0.036989 (rank : 227)	θ value	1.81305 (rank : 154)
Query Neighborhood Hits	277	Target Neighborhood Hits	32	Shared Neighborhood Hits	15
SwissProt Accessions	Q64112, Q62385	Gene names	Ifit2, Garg39, Ifi54
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 2 (IFIT-2) (Interferon-induced 54 kDa protein) (IFI-54K) (Glucocorticoid- attenuated response gene 39 protein) (GARG-39).

GSDM1_HUMAN
NC score	0.036958 (rank : 228)	θ value	1.38821 (rank : 137)
Query Neighborhood Hits	277	Target Neighborhood Hits	32	Shared Neighborhood Hits	6
SwissProt Accessions	Q96QA5, Q8N1M6	Gene names	GSDM1, GSDM
Domain Architecture	No domain graphic available
Description	Gasdermin.

NFL_HUMAN
NC score	0.036694 (rank : 229)	θ value	0.21417 (rank : 69)
Query Neighborhood Hits	277	Target Neighborhood Hits	666	Shared Neighborhood Hits	49
SwissProt Accessions	P07196, Q16154, Q8IU72	Gene names	NEFL, NF68, NFL
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

MAP2_MOUSE
NC score	0.036635 (rank : 230)	θ value	2.36792 (rank : 173)
Query Neighborhood Hits	277	Target Neighborhood Hits	342	Shared Neighborhood Hits	47
SwissProt Accessions	P20357	Gene names	Map2, Mtap2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2).

HUWE1_HUMAN
NC score	0.036587 (rank : 231)	θ value	0.62314 (rank : 100)
Query Neighborhood Hits	277	Target Neighborhood Hits	443	Shared Neighborhood Hits	28
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

AATF_MOUSE
NC score	0.035892 (rank : 232)	θ value	4.03905 (rank : 194)
Query Neighborhood Hits	277	Target Neighborhood Hits	50	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JKX4, Q7TQN1, Q8C5Q2, Q99P89	Gene names	Aatf, Che1, Trb
Domain Architecture	No domain graphic available
Description	Protein AATF (Apoptosis-antagonizing transcription factor) (Rb-binding protein Che-1) (Traube protein).

HNRCL_HUMAN
NC score	0.035486 (rank : 233)	θ value	2.36792 (rank : 171)
Query Neighborhood Hits	277	Target Neighborhood Hits	232	Shared Neighborhood Hits	10
SwissProt Accessions	O60812	Gene names	HNRPCL1
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein C-like 1 (hnRNP core protein C-like 1).

HUWE1_MOUSE
NC score	0.035435 (rank : 234)	θ value	0.62314 (rank : 101)
Query Neighborhood Hits	277	Target Neighborhood Hits	406	Shared Neighborhood Hits	24
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

ABCF1_HUMAN
NC score	0.035254 (rank : 235)	θ value	2.36792 (rank : 161)
Query Neighborhood Hits	277	Target Neighborhood Hits	343	Shared Neighborhood Hits	33
SwissProt Accessions	Q8NE71, O14897, Q69YP6	Gene names	ABCF1, ABC50
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein).

APLP2_HUMAN
NC score	0.034245 (rank : 236)	θ value	0.813845 (rank : 103)
Query Neighborhood Hits	277	Target Neighborhood Hits	193	Shared Neighborhood Hits	17
SwissProt Accessions	Q06481	Gene names	APLP2, APPL2
Domain Architecture
Description	Amyloid-like protein 2 precursor (Amyloid protein homolog) (APPH) (CDEI box-binding protein) (CDEBP).

BRD2_HUMAN
NC score	0.033916 (rank : 237)	θ value	3.0926 (rank : 182)
Query Neighborhood Hits	277	Target Neighborhood Hits	242	Shared Neighborhood Hits	23
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

WDR43_HUMAN
NC score	0.033741 (rank : 238)	θ value	6.88961 (rank : 252)
Query Neighborhood Hits	277	Target Neighborhood Hits	269	Shared Neighborhood Hits	22
SwissProt Accessions	Q15061, Q15395, Q92577	Gene names	WDR43, KIAA0007
Domain Architecture	No domain graphic available
Description	WD repeat protein 43.

GOGA4_HUMAN
NC score	0.033683 (rank : 239)	θ value	5.27518 (rank : 213)
Query Neighborhood Hits	277	Target Neighborhood Hits	2034	Shared Neighborhood Hits	119
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

NCKX1_HUMAN
NC score	0.033652 (rank : 240)	θ value	6.88961 (rank : 244)
Query Neighborhood Hits	277	Target Neighborhood Hits	223	Shared Neighborhood Hits	27
SwissProt Accessions	O60721, O43485, O75184	Gene names	SLC24A1, KIAA0702, NCKX1
Domain Architecture
Description	Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) (Retinal rod Na-Ca+K exchanger).

MYST4_MOUSE
NC score	0.033292 (rank : 241)	θ value	5.27518 (rank : 220)
Query Neighborhood Hits	277	Target Neighborhood Hits	416	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

NFL_MOUSE
NC score	0.033165 (rank : 242)	θ value	0.47712 (rank : 93)
Query Neighborhood Hits	277	Target Neighborhood Hits	695	Shared Neighborhood Hits	46
SwissProt Accessions	P08551, Q8K0Z0	Gene names	Nefl, Nf68, Nfl
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

MLL3_HUMAN
NC score	0.033117 (rank : 243)	θ value	5.27518 (rank : 219)
Query Neighborhood Hits	277	Target Neighborhood Hits	1644	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

AR13B_HUMAN
NC score	0.032122 (rank : 244)	θ value	4.03905 (rank : 196)
Query Neighborhood Hits	277	Target Neighborhood Hits	528	Shared Neighborhood Hits	64
SwissProt Accessions	Q3SXY8, Q504W8	Gene names	ARL13B, ARL2L1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 2-like 1) (ARL2-like protein 1).

CHD6_HUMAN
NC score	0.032075 (rank : 245)	θ value	1.06291 (rank : 120)
Query Neighborhood Hits	277	Target Neighborhood Hits	342	Shared Neighborhood Hits	39
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

CI093_HUMAN
NC score	0.031584 (rank : 246)	θ value	4.03905 (rank : 198)
Query Neighborhood Hits	277	Target Neighborhood Hits	1088	Shared Neighborhood Hits	72
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

CRNL1_MOUSE
NC score	0.031525 (rank : 247)	θ value	5.27518 (rank : 211)
Query Neighborhood Hits	277	Target Neighborhood Hits	72	Shared Neighborhood Hits	9
SwissProt Accessions	P63154, Q542E8, Q9CQC1	Gene names	Crnkl1
Domain Architecture	No domain graphic available
Description	Crooked neck-like protein 1 (Crooked neck homolog).

SYCP1_HUMAN
NC score	0.031338 (rank : 248)	θ value	5.27518 (rank : 226)
Query Neighborhood Hits	277	Target Neighborhood Hits	1313	Shared Neighborhood Hits	88
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

CHD2_HUMAN
NC score	0.031267 (rank : 249)	θ value	4.03905 (rank : 197)
Query Neighborhood Hits	277	Target Neighborhood Hits	360	Shared Neighborhood Hits	30
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

ARI4A_HUMAN
NC score	0.031021 (rank : 250)	θ value	8.99809 (rank : 256)
Query Neighborhood Hits	277	Target Neighborhood Hits	434	Shared Neighborhood Hits	45
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

CHD4_HUMAN
NC score	0.030861 (rank : 251)	θ value	0.813845 (rank : 108)
Query Neighborhood Hits	277	Target Neighborhood Hits	365	Shared Neighborhood Hits	33
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CENPE_HUMAN
NC score	0.030847 (rank : 252)	θ value	6.88961 (rank : 235)
Query Neighborhood Hits	277	Target Neighborhood Hits	2060	Shared Neighborhood Hits	116
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

HDAC1_HUMAN
NC score	0.030218 (rank : 253)	θ value	1.06291 (rank : 124)
Query Neighborhood Hits	277	Target Neighborhood Hits	49	Shared Neighborhood Hits	12
SwissProt Accessions	Q13547, Q92534	Gene names	HDAC1, RPD3L1
Domain Architecture
Description	Histone deacetylase 1 (HD1).

HDAC1_MOUSE
NC score	0.030067 (rank : 254)	θ value	1.06291 (rank : 125)
Query Neighborhood Hits	277	Target Neighborhood Hits	46	Shared Neighborhood Hits	12
SwissProt Accessions	O09106, P97476	Gene names	Hdac1
Domain Architecture
Description	Histone deacetylase 1 (HD1).

ZCHC9_HUMAN
NC score	0.029857 (rank : 255)	θ value	3.0926 (rank : 193)
Query Neighborhood Hits	277	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N567, Q9H027	Gene names	ZCCHC9
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 9.

TBC16_HUMAN
NC score	0.029827 (rank : 256)	θ value	2.36792 (rank : 179)
Query Neighborhood Hits	277	Target Neighborhood Hits	55	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TBP0	Gene names	TBC1D16
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 16.

MYO10_HUMAN
NC score	0.029658 (rank : 257)	θ value	0.125558 (rank : 53)
Query Neighborhood Hits	277	Target Neighborhood Hits	920	Shared Neighborhood Hits	66
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

WDR60_MOUSE
NC score	0.029327 (rank : 258)	θ value	6.88961 (rank : 253)
Query Neighborhood Hits	277	Target Neighborhood Hits	344	Shared Neighborhood Hits	34
SwissProt Accessions	Q8C761, Q3UNM4	Gene names	Wdr60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

RYR1_HUMAN
NC score	0.028982 (rank : 259)	θ value	3.0926 (rank : 190)
Query Neighborhood Hits	277	Target Neighborhood Hits	303	Shared Neighborhood Hits	28
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

IF2M_MOUSE
NC score	0.028474 (rank : 260)	θ value	5.27518 (rank : 216)
Query Neighborhood Hits	277	Target Neighborhood Hits	183	Shared Neighborhood Hits	27
SwissProt Accessions	Q91YJ5	Gene names	Mtif2
Domain Architecture
Description	Translation initiation factor IF-2, mitochondrial precursor (IF-2Mt) (IF-2(Mt)).

SMC4_HUMAN
NC score	0.028286 (rank : 261)	θ value	1.38821 (rank : 144)
Query Neighborhood Hits	277	Target Neighborhood Hits	937	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

NP1L3_HUMAN
NC score	0.027907 (rank : 262)	θ value	6.88961 (rank : 246)
Query Neighborhood Hits	277	Target Neighborhood Hits	172	Shared Neighborhood Hits	27
SwissProt Accessions	Q99457, O60788	Gene names	NAP1L3, BNAP
Domain Architecture
Description	Nucleosome assembly protein 1-like 3.

PCLO_HUMAN
NC score	0.027865 (rank : 263)	θ value	2.36792 (rank : 175)
Query Neighborhood Hits	277	Target Neighborhood Hits	2046	Shared Neighborhood Hits	90
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SMC4_MOUSE
NC score	0.027521 (rank : 264)	θ value	2.36792 (rank : 178)
Query Neighborhood Hits	277	Target Neighborhood Hits	830	Shared Neighborhood Hits	43
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

TOP1_MOUSE
NC score	0.027305 (rank : 265)	θ value	8.99809 (rank : 274)
Query Neighborhood Hits	277	Target Neighborhood Hits	213	Shared Neighborhood Hits	24
SwissProt Accessions	Q04750	Gene names	Top1, Top-1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

AKAP9_HUMAN
NC score	0.026487 (rank : 266)	θ value	4.03905 (rank : 195)
Query Neighborhood Hits	277	Target Neighborhood Hits	1710	Shared Neighborhood Hits	92
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

DDX21_MOUSE
NC score	0.026357 (rank : 267)	θ value	3.0926 (rank : 186)
Query Neighborhood Hits	277	Target Neighborhood Hits	350	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

MLL3_MOUSE
NC score	0.026275 (rank : 268)	θ value	8.99809 (rank : 266)
Query Neighborhood Hits	277	Target Neighborhood Hits	1399	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

ANR11_HUMAN
NC score	0.025888 (rank : 269)	θ value	5.27518 (rank : 209)
Query Neighborhood Hits	277	Target Neighborhood Hits	1289	Shared Neighborhood Hits	89
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

ANXA7_HUMAN
NC score	0.025656 (rank : 270)	θ value	0.163984 (rank : 60)
Query Neighborhood Hits	277	Target Neighborhood Hits	168	Shared Neighborhood Hits	5
SwissProt Accessions	P20073	Gene names	ANXA7, ANX7, SNX
Domain Architecture
Description	Annexin A7 (Annexin VII) (Synexin).

HAP1_HUMAN
NC score	0.025313 (rank : 271)	θ value	1.81305 (rank : 153)
Query Neighborhood Hits	277	Target Neighborhood Hits	606	Shared Neighborhood Hits	31
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

AN30A_HUMAN
NC score	0.024881 (rank : 272)	θ value	5.27518 (rank : 208)
Query Neighborhood Hits	277	Target Neighborhood Hits	1119	Shared Neighborhood Hits	77
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

DMD_HUMAN
NC score	0.024794 (rank : 273)	θ value	4.03905 (rank : 200)
Query Neighborhood Hits	277	Target Neighborhood Hits	1135	Shared Neighborhood Hits	69
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

KI21B_HUMAN
NC score	0.024760 (rank : 274)	θ value	4.03905 (rank : 203)
Query Neighborhood Hits	277	Target Neighborhood Hits	1017	Shared Neighborhood Hits	54
SwissProt Accessions	O75037, Q5T4J3	Gene names	KIF21B, KIAA0449
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B.

ZN326_MOUSE
NC score	0.024592 (rank : 275)	θ value	6.88961 (rank : 254)
Query Neighborhood Hits	277	Target Neighborhood Hits	117	Shared Neighborhood Hits	18
SwissProt Accessions	O88291, Q8BSJ5, Q8K1X9, Q9CYG9	Gene names	Znf326, Zan75, Zfp326
Domain Architecture	No domain graphic available
Description	Zinc finger protein 326 (Zinc finger protein-associated with nuclear matrix of 75 kDa).

CYLN2_MOUSE
NC score	0.024084 (rank : 276)	θ value	2.36792 (rank : 167)
Query Neighborhood Hits	277	Target Neighborhood Hits	1002	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

TOP1_HUMAN
NC score	0.023954 (rank : 277)	θ value	8.99809 (rank : 273)
Query Neighborhood Hits	277	Target Neighborhood Hits	207	Shared Neighborhood Hits	29
SwissProt Accessions	P11387, O43256, Q12855, Q12856, Q15610, Q5TFY3, Q9UJN0	Gene names	TOP1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

RTN1_HUMAN
NC score	0.023034 (rank : 278)	θ value	6.88961 (rank : 247)
Query Neighborhood Hits	277	Target Neighborhood Hits	173	Shared Neighborhood Hits	12
SwissProt Accessions	Q16799, Q16800, Q16801	Gene names	RTN1, NSP
Domain Architecture
Description	Reticulon-1 (Neuroendocrine-specific protein).

KI21B_MOUSE
NC score	0.023021 (rank : 279)	θ value	6.88961 (rank : 241)
Query Neighborhood Hits	277	Target Neighborhood Hits	997	Shared Neighborhood Hits	53
SwissProt Accessions	Q9QXL1, P97424	Gene names	Kif21b, Kif6
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B (Kinesin-like protein KIF6).

MYO5A_MOUSE
NC score	0.022996 (rank : 280)	θ value	1.81305 (rank : 156)
Query Neighborhood Hits	277	Target Neighborhood Hits	1117	Shared Neighborhood Hits	76
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

CHD8_HUMAN
NC score	0.022063 (rank : 281)	θ value	8.99809 (rank : 260)
Query Neighborhood Hits	277	Target Neighborhood Hits	235	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

CTTB2_HUMAN
NC score	0.021417 (rank : 282)	θ value	2.36792 (rank : 166)
Query Neighborhood Hits	277	Target Neighborhood Hits	1061	Shared Neighborhood Hits	44
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

FGL2_HUMAN
NC score	0.021193 (rank : 283)	θ value	0.813845 (rank : 109)
Query Neighborhood Hits	277	Target Neighborhood Hits	101	Shared Neighborhood Hits	8
SwissProt Accessions	Q14314	Gene names	FGL2
Domain Architecture
Description	Fibroleukin precursor (Fibrinogen-like protein 2) (pT49).

MYPT2_HUMAN
NC score	0.020933 (rank : 284)	θ value	3.0926 (rank : 189)
Query Neighborhood Hits	277	Target Neighborhood Hits	707	Shared Neighborhood Hits	39
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

PEG3_MOUSE
NC score	0.020926 (rank : 285)	θ value	0.21417 (rank : 72)
Query Neighborhood Hits	277	Target Neighborhood Hits	1101	Shared Neighborhood Hits	87
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

CTF1_MOUSE
NC score	0.020286 (rank : 286)	θ value	4.03905 (rank : 199)
Query Neighborhood Hits	277	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q60753	Gene names	Ctf1
Domain Architecture	No domain graphic available
Description	Cardiotrophin-1 (CT-1).

ATAD2_MOUSE
NC score	0.020283 (rank : 287)	θ value	0.279714 (rank : 74)
Query Neighborhood Hits	277	Target Neighborhood Hits	167	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CDM1	Gene names	Atad2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

CD2L1_HUMAN
NC score	0.020029 (rank : 288)	θ value	0.0736092 (rank : 45)
Query Neighborhood Hits	277	Target Neighborhood Hits	1467	Shared Neighborhood Hits	68
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

CCDC3_MOUSE
NC score	0.019496 (rank : 289)	θ value	8.99809 (rank : 258)
Query Neighborhood Hits	277	Target Neighborhood Hits	131	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D6Y1	Gene names	Ccdc3
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 3 precursor.

TRI37_MOUSE
NC score	0.018510 (rank : 290)	θ value	5.27518 (rank : 229)
Query Neighborhood Hits	277	Target Neighborhood Hits	316	Shared Neighborhood Hits	22
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

CD2L1_MOUSE
NC score	0.017720 (rank : 291)	θ value	0.813845 (rank : 107)
Query Neighborhood Hits	277	Target Neighborhood Hits	1463	Shared Neighborhood Hits	73
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

SAFB1_HUMAN
NC score	0.016529 (rank : 292)	θ value	8.99809 (rank : 270)
Query Neighborhood Hits	277	Target Neighborhood Hits	493	Shared Neighborhood Hits	30
SwissProt Accessions	Q15424, O60406, Q59HH8	Gene names	SAFB, HAP, HET, SAFB1
Domain Architecture
Description	Scaffold attachment factor B (Scaffold attachment factor B1) (SAF-B) (HSP27 estrogen response element-TATA box-binding protein) (HSP27 ERE- TATA-binding protein).

CD2L2_HUMAN
NC score	0.015894 (rank : 293)	θ value	1.06291 (rank : 119)
Query Neighborhood Hits	277	Target Neighborhood Hits	1439	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

CPSF2_HUMAN
NC score	0.015756 (rank : 294)	θ value	8.99809 (rank : 261)
Query Neighborhood Hits	277	Target Neighborhood Hits	34	Shared Neighborhood Hits	7
SwissProt Accessions	Q9P2I0, Q6NSJ1, Q9H3W7	Gene names	CPSF2, CPSF100, KIAA1367
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 100 kDa subunit (CPSF 100 kDa subunit).

NOG2_HUMAN
NC score	0.015681 (rank : 295)	θ value	4.03905 (rank : 204)
Query Neighborhood Hits	277	Target Neighborhood Hits	117	Shared Neighborhood Hits	10
SwissProt Accessions	Q13823, Q9BWN7	Gene names	GNL2, NGP1
Domain Architecture
Description	Nucleolar GTP-binding protein 2 (Autoantigen NGP-1).

ANR18_HUMAN
NC score	0.015485 (rank : 296)	θ value	3.0926 (rank : 181)
Query Neighborhood Hits	277	Target Neighborhood Hits	1106	Shared Neighborhood Hits	54
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

DDX21_HUMAN
NC score	0.015252 (rank : 297)	θ value	5.27518 (rank : 212)
Query Neighborhood Hits	277	Target Neighborhood Hits	308	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

HSP74_MOUSE
NC score	0.015124 (rank : 298)	θ value	8.99809 (rank : 264)
Query Neighborhood Hits	277	Target Neighborhood Hits	257	Shared Neighborhood Hits	30
SwissProt Accessions	Q61316	Gene names	Hspa4, Hsp110
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2).

PRG4_MOUSE
NC score	0.015078 (rank : 299)	θ value	8.99809 (rank : 269)
Query Neighborhood Hits	277	Target Neighborhood Hits	624	Shared Neighborhood Hits	32
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

DDX27_HUMAN
NC score	0.014598 (rank : 300)	θ value	1.81305 (rank : 151)
Query Neighborhood Hits	277	Target Neighborhood Hits	197	Shared Neighborhood Hits	20
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

UHRF2_MOUSE
NC score	0.014539 (rank : 301)	θ value	6.88961 (rank : 250)
Query Neighborhood Hits	277	Target Neighborhood Hits	275	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

TCF8_HUMAN
NC score	0.014144 (rank : 302)	θ value	0.279714 (rank : 78)
Query Neighborhood Hits	277	Target Neighborhood Hits	1057	Shared Neighborhood Hits	54
SwissProt Accessions	P37275, Q12924, Q13800	Gene names	TCF8, AREB6
Domain Architecture
Description	Transcription factor 8 (NIL-2-A zinc finger protein) (Negative regulator of IL2).

TF3C2_MOUSE
NC score	0.013841 (rank : 303)	θ value	8.99809 (rank : 272)
Query Neighborhood Hits	277	Target Neighborhood Hits	165	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BL74, Q3U7Z9, Q80XQ7, Q8BJJ4, Q8BLP3, Q8K1J1, Q9CSS0, Q9CVE6, Q9DBK6	Gene names	Gtf3c2, Kiaa0011
Domain Architecture
Description	General transcription factor 3C polypeptide 2 (Transcription factor IIIC-subunit beta) (TF3C-beta) (TFIIIC 110 kDa subunit) (TFIIIC110).

CENPH_MOUSE
NC score	0.013775 (rank : 304)	θ value	8.99809 (rank : 259)
Query Neighborhood Hits	277	Target Neighborhood Hits	195	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QYM8, Q8R3K9, Q9D079, Q9D0N1	Gene names	Cenph, Enp
Domain Architecture	No domain graphic available
Description	Centromere protein H (CENP-H).

EHMT2_HUMAN
NC score	0.013189 (rank : 305)	θ value	6.88961 (rank : 237)
Query Neighborhood Hits	277	Target Neighborhood Hits	498	Shared Neighborhood Hits	31
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

TDRD6_MOUSE
NC score	0.012678 (rank : 306)	θ value	6.88961 (rank : 248)
Query Neighborhood Hits	277	Target Neighborhood Hits	82	Shared Neighborhood Hits	4
SwissProt Accessions	P61407	Gene names	Tdrd6
Domain Architecture
Description	Tudor domain-containing protein 6.

K1967_HUMAN
NC score	0.012503 (rank : 307)	θ value	6.88961 (rank : 240)
Query Neighborhood Hits	277	Target Neighborhood Hits	136	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N163, Q6P0Q9, Q8N3G7, Q8N8M1, Q8TF34, Q9H9Q9, Q9HD12, Q9NT55	Gene names	KIAA1967, DBC1
Domain Architecture	No domain graphic available
Description	Protein KIAA1967 (Deleted in breast cancer gene 1 protein) (DBC.1) (DBC-1) (p30 DBC).

TTBK1_HUMAN
NC score	0.012482 (rank : 308)	θ value	3.0926 (rank : 192)
Query Neighborhood Hits	277	Target Neighborhood Hits	1058	Shared Neighborhood Hits	33
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

DDX49_HUMAN
NC score	0.011841 (rank : 309)	θ value	1.06291 (rank : 121)
Query Neighborhood Hits	277	Target Neighborhood Hits	223	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

ANK3_HUMAN
NC score	0.011507 (rank : 310)	θ value	8.99809 (rank : 255)
Query Neighborhood Hits	277	Target Neighborhood Hits	853	Shared Neighborhood Hits	67
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

SPTA1_HUMAN
NC score	0.010609 (rank : 311)	θ value	5.27518 (rank : 225)
Query Neighborhood Hits	277	Target Neighborhood Hits	748	Shared Neighborhood Hits	34
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

GMIP_HUMAN
NC score	0.010289 (rank : 312)	θ value	2.36792 (rank : 170)
Query Neighborhood Hits	277	Target Neighborhood Hits	225	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

CXA8_HUMAN
NC score	0.009892 (rank : 313)	θ value	3.0926 (rank : 184)
Query Neighborhood Hits	277	Target Neighborhood Hits	65	Shared Neighborhood Hits	3
SwissProt Accessions	P48165, Q9NP25	Gene names	GJA8
Domain Architecture
Description	Gap junction alpha-8 protein (Connexin-50) (Cx50) (Lens fiber protein MP70).

SLK_HUMAN
NC score	0.009449 (rank : 314)	θ value	1.06291 (rank : 131)
Query Neighborhood Hits	277	Target Neighborhood Hits	1775	Shared Neighborhood Hits	82
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

HXC10_MOUSE
NC score	0.009346 (rank : 315)	θ value	3.0926 (rank : 187)
Query Neighborhood Hits	277	Target Neighborhood Hits	417	Shared Neighborhood Hits	20
SwissProt Accessions	P31257, P31312, Q7TMT7	Gene names	Hoxc10, Hox-3.6, Hoxc-10
Domain Architecture	No domain graphic available
Description	Homeobox protein Hox-C10 (Hox-3.6).

NMT2_MOUSE
NC score	0.008791 (rank : 316)	θ value	6.88961 (rank : 245)
Query Neighborhood Hits	277	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	O70311	Gene names	Nmt2
Domain Architecture
Description	Glycylpeptide N-tetradecanoyltransferase 2 (EC 2.3.1.97) (Peptide N- myristoyltransferase 2) (Myristoyl-CoA:protein N-myristoyltransferase 2) (NMT 2) (Type II N-myristoyltransferase).

LRCH2_MOUSE
NC score	0.008323 (rank : 317)	θ value	3.0926 (rank : 188)
Query Neighborhood Hits	277	Target Neighborhood Hits	287	Shared Neighborhood Hits	8
SwissProt Accessions	Q3UMG5, Q7TNP9, Q80TC9	Gene names	Lrch2, Kiaa1495
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 2.

HXC10_HUMAN
NC score	0.008322 (rank : 318)	θ value	5.27518 (rank : 215)
Query Neighborhood Hits	277	Target Neighborhood Hits	417	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NYD6, O15219, O15220, Q9BVD5	Gene names	HOXC10
Domain Architecture
Description	Homeobox protein Hox-C10.

TCF8_MOUSE
NC score	0.007756 (rank : 319)	θ value	5.27518 (rank : 228)
Query Neighborhood Hits	277	Target Neighborhood Hits	1067	Shared Neighborhood Hits	39
SwissProt Accessions	Q64318, Q62519	Gene names	Tcf8, Zfhx1a, Zfx1a, Zfx1ha
Domain Architecture
Description	Transcription factor 8 (Zinc finger homeobox protein 1a) (MEB1) (Delta EF1).

SCN4A_HUMAN
NC score	0.006828 (rank : 320)	θ value	5.27518 (rank : 223)
Query Neighborhood Hits	277	Target Neighborhood Hits	133	Shared Neighborhood Hits	6
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

KCC4_MOUSE
NC score	0.006092 (rank : 321)	θ value	0.0431538 (rank : 41)
Query Neighborhood Hits	277	Target Neighborhood Hits	899	Shared Neighborhood Hits	13
SwissProt Accessions	P08414, Q61381	Gene names	Camk4
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type IV (EC 2.7.11.17) (CAM kinase-GR) (CaMK IV).

LAP4_HUMAN
NC score	0.003945 (rank : 322)	θ value	5.27518 (rank : 217)
Query Neighborhood Hits	277	Target Neighborhood Hits	608	Shared Neighborhood Hits	18
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

CPT1A_HUMAN
NC score	0.003875 (rank : 323)	θ value	8.99809 (rank : 262)
Query Neighborhood Hits	277	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	P50416, Q8TCU0, Q9BWK0	Gene names	CPT1A, CPT1
Domain Architecture
Description	Carnitine O-palmitoyltransferase I, liver isoform (EC 2.3.1.21) (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A).

FBLN2_MOUSE
NC score	0.000031 (rank : 324)	θ value	6.88961 (rank : 238)
Query Neighborhood Hits	277	Target Neighborhood Hits	505	Shared Neighborhood Hits	12
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

CSPG3_HUMAN
NC score	-0.001025 (rank : 325)	θ value	8.99809 (rank : 263)
Query Neighborhood Hits	277	Target Neighborhood Hits	676	Shared Neighborhood Hits	11
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CTCF_HUMAN
NC score	-0.003524 (rank : 326)	θ value	6.88961 (rank : 236)
Query Neighborhood Hits	277	Target Neighborhood Hits	764	Shared Neighborhood Hits	12
SwissProt Accessions	P49711	Gene names	CTCF
Domain Architecture
Description	Transcriptional repressor CTCF (CCCTC-binding factor) (CTCFL paralog) (11-zinc finger protein).