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Network neighborhood for query Sequence : ITAM_HUMAN

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ITAM_HUMAN
SwissProt Accessions	P11215	Gene names	ITGAM, CD11B, CR3A
Domain Architecture
Description	Integrin alpha-M precursor (Cell surface glycoprotein MAC-1 alpha subunit) (CR-3 alpha chain) (Leukocyte adhesion receptor MO1) (Neutrophil adherence receptor) (CD11b antigen).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ITAD_HUMAN
θ value	0 (rank : 1)	NC score	0.994244 (rank : 5)
Query Neighborhood Hits	78	Target Neighborhood Hits	67	Shared Neighborhood Hits	59
SwissProt Accessions	Q13349, Q15575, Q15576	Gene names	ITGAD
Domain Architecture
Description	Integrin alpha-D precursor (Leukointegrin alpha D) (ADB2) (CD11d antigen).

ITAD_MOUSE
θ value	0 (rank : 2)	NC score	0.995100 (rank : 4)
Query Neighborhood Hits	78	Target Neighborhood Hits	85	Shared Neighborhood Hits	60
SwissProt Accessions	Q3V0T4	Gene names	Itgad
Domain Architecture	No domain graphic available
Description	Integrin alpha-D precursor (CD11d antigen).

ITAM_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	78	Target Neighborhood Hits	78	Shared Neighborhood Hits	78
SwissProt Accessions	P11215	Gene names	ITGAM, CD11B, CR3A
Domain Architecture
Description	Integrin alpha-M precursor (Cell surface glycoprotein MAC-1 alpha subunit) (CR-3 alpha chain) (Leukocyte adhesion receptor MO1) (Neutrophil adherence receptor) (CD11b antigen).

ITAM_MOUSE
θ value	0 (rank : 4)	NC score	0.996836 (rank : 2)
Query Neighborhood Hits	78	Target Neighborhood Hits	77	Shared Neighborhood Hits	65
SwissProt Accessions	P05555, Q8CA73	Gene names	Itgam
Domain Architecture
Description	Integrin alpha-M precursor (Cell surface glycoprotein MAC-1 alpha subunit) (CR-3 alpha chain) (Leukocyte adhesion receptor MO1) (CD11b antigen).

ITAX_HUMAN
θ value	0 (rank : 5)	NC score	0.994212 (rank : 6)
Query Neighborhood Hits	78	Target Neighborhood Hits	81	Shared Neighborhood Hits	61
SwissProt Accessions	P20702, Q8IVA6	Gene names	ITGAX, CD11C
Domain Architecture
Description	Integrin alpha-X precursor (Leukocyte adhesion glycoprotein p150,95 alpha chain) (Leukocyte adhesion receptor p150,95) (Leu M5) (CD11c antigen).

ITAX_MOUSE
θ value	0 (rank : 6)	NC score	0.995859 (rank : 3)
Query Neighborhood Hits	78	Target Neighborhood Hits	69	Shared Neighborhood Hits	60
SwissProt Accessions	Q9QXH4	Gene names	Itgax
Domain Architecture
Description	Integrin alpha-X precursor (Leukocyte adhesion glycoprotein p150,95 alpha chain) (Leukocyte adhesion receptor p150,95) (CD11c antigen).

ITAL_HUMAN
θ value	1.16101e-156 (rank : 7)	NC score	0.977998 (rank : 7)
Query Neighborhood Hits	78	Target Neighborhood Hits	71	Shared Neighborhood Hits	60
SwissProt Accessions	P20701, O43746, Q45H73, Q9UBC8	Gene names	ITGAL, CD11A
Domain Architecture
Description	Integrin alpha-L precursor (Leukocyte adhesion glycoprotein LFA-1 alpha chain) (LFA-1A) (Leukocyte function-associated molecule 1 alpha chain) (CD11a antigen).

ITAL_MOUSE
θ value	2.18956e-155 (rank : 8)	NC score	0.977744 (rank : 8)
Query Neighborhood Hits	78	Target Neighborhood Hits	68	Shared Neighborhood Hits	60
SwissProt Accessions	P24063	Gene names	Itgal, Lfa-1, Ly-15
Domain Architecture
Description	Integrin alpha-L precursor (Leukocyte adhesion glycoprotein LFA-1 alpha chain) (LFA-1A) (Leukocyte function-associated molecule 1 alpha chain) (Lymphocyte antigen Ly-15) (CD11a antigen).

ITAE_HUMAN
θ value	3.42535e-108 (rank : 9)	NC score	0.962048 (rank : 9)
Query Neighborhood Hits	78	Target Neighborhood Hits	77	Shared Neighborhood Hits	60
SwissProt Accessions	P38570, Q9NZU9	Gene names	ITGAE
Domain Architecture
Description	Integrin alpha-E precursor (Mucosal lymphocyte 1 antigen) (HML-1 antigen) (Integrin alpha-IEL) (CD103 antigen) [Contains: Integrin alpha-E light chain; Integrin alpha-E heavy chain].

ITAE_MOUSE
θ value	1.48926e-103 (rank : 10)	NC score	0.961314 (rank : 10)
Query Neighborhood Hits	78	Target Neighborhood Hits	73	Shared Neighborhood Hits	60
SwissProt Accessions	Q60677	Gene names	Itgae
Domain Architecture
Description	Integrin alpha-E precursor (Integrin alpha M290) (CD103 antigen) [Contains: Integrin alpha-E light chain; Integrin alpha-E heavy chain].

ITA1_HUMAN
θ value	4.79078e-102 (rank : 11)	NC score	0.952221 (rank : 12)
Query Neighborhood Hits	78	Target Neighborhood Hits	75	Shared Neighborhood Hits	59
SwissProt Accessions	P56199	Gene names	ITGA1
Domain Architecture	No domain graphic available
Description	Integrin alpha-1 (Laminin and collagen receptor) (VLA-1) (CD49a antigen).

ITA11_HUMAN
θ value	4.95767e-99 (rank : 12)	NC score	0.950958 (rank : 13)
Query Neighborhood Hits	78	Target Neighborhood Hits	70	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UKX5, Q8WYI8, Q9UKQ1	Gene names	ITGA11
Domain Architecture
Description	Integrin alpha-11 precursor.

ITA10_HUMAN
θ value	1.22112e-97 (rank : 13)	NC score	0.952443 (rank : 11)
Query Neighborhood Hits	78	Target Neighborhood Hits	67	Shared Neighborhood Hits	58
SwissProt Accessions	O75578, Q6UXJ6, Q9UHZ8	Gene names	ITGA10
Domain Architecture
Description	Integrin alpha-10 precursor.

ITA2_MOUSE
θ value	2.08291e-97 (rank : 14)	NC score	0.947758 (rank : 15)
Query Neighborhood Hits	78	Target Neighborhood Hits	70	Shared Neighborhood Hits	58
SwissProt Accessions	Q62469, Q62163	Gene names	Itga2
Domain Architecture
Description	Integrin alpha-2 precursor (Platelet membrane glycoprotein Ia) (GPIa) (Collagen receptor) (VLA-2 alpha chain) (CD49b antigen).

ITA2_HUMAN
θ value	1.49272e-95 (rank : 15)	NC score	0.946551 (rank : 16)
Query Neighborhood Hits	78	Target Neighborhood Hits	64	Shared Neighborhood Hits	58
SwissProt Accessions	P17301, Q14595	Gene names	ITGA2
Domain Architecture
Description	Integrin alpha-2 precursor (Platelet membrane glycoprotein Ia) (GPIa) (Collagen receptor) (VLA-2 alpha chain) (CD49b antigen).

ITA11_MOUSE
θ value	8.19079e-94 (rank : 16)	NC score	0.948418 (rank : 14)
Query Neighborhood Hits	78	Target Neighborhood Hits	70	Shared Neighborhood Hits	60
SwissProt Accessions	P61622	Gene names	Itga11
Domain Architecture
Description	Integrin alpha-11 precursor.

ITA4_MOUSE
θ value	1.66964e-54 (rank : 17)	NC score	0.843711 (rank : 18)
Query Neighborhood Hits	78	Target Neighborhood Hits	48	Shared Neighborhood Hits	35
SwissProt Accessions	Q00651	Gene names	Itga4
Domain Architecture
Description	Integrin alpha-4 precursor (Integrin alpha-IV) (VLA-4) (Lymphocyte Peyer patch adhesion molecules subunit alpha) (LPAM subunit alpha) (CD49d antigen).

ITA4_HUMAN
θ value	1.01294e-51 (rank : 18)	NC score	0.839780 (rank : 19)
Query Neighborhood Hits	78	Target Neighborhood Hits	45	Shared Neighborhood Hits	35
SwissProt Accessions	P13612	Gene names	ITGA4
Domain Architecture
Description	Integrin alpha-4 precursor (Integrin alpha-IV) (VLA-4) (CD49d antigen).

ITA9_HUMAN
θ value	1.91031e-50 (rank : 19)	NC score	0.845771 (rank : 17)
Query Neighborhood Hits	78	Target Neighborhood Hits	47	Shared Neighborhood Hits	35
SwissProt Accessions	Q13797, Q14638	Gene names	ITGA9
Domain Architecture
Description	Integrin alpha-9 precursor (Integrin alpha-RLC).

ITA3_MOUSE
θ value	1.12253e-42 (rank : 20)	NC score	0.805944 (rank : 20)
Query Neighborhood Hits	78	Target Neighborhood Hits	54	Shared Neighborhood Hits	35
SwissProt Accessions	Q62470, Q08441, Q08442	Gene names	Itga3
Domain Architecture
Description	Integrin alpha-3 precursor (Galactoprotein B3) (GAPB3) (VLA-3 alpha chain) (CD49c antigen) [Contains: Integrin alpha-3 heavy chain; Integrin alpha-3 light chain].

ITA3_HUMAN
θ value	9.83387e-39 (rank : 21)	NC score	0.805001 (rank : 21)
Query Neighborhood Hits	78	Target Neighborhood Hits	42	Shared Neighborhood Hits	35
SwissProt Accessions	P26006	Gene names	ITGA3
Domain Architecture
Description	Integrin alpha-3 precursor (Galactoprotein B3) (GAPB3) (VLA-3 alpha chain) (FRP-2) (CD49c antigen) [Contains: Integrin alpha-3 heavy chain; Integrin alpha-3 light chain].

ITAV_MOUSE
θ value	8.32485e-38 (rank : 22)	NC score	0.780182 (rank : 22)
Query Neighborhood Hits	78	Target Neighborhood Hits	43	Shared Neighborhood Hits	35
SwissProt Accessions	P43406	Gene names	Itgav
Domain Architecture
Description	Integrin alpha-V precursor (Vitronectin receptor subunit alpha) (CD51 antigen) [Contains: Integrin alpha-V heavy chain; Integrin alpha-V light chain].

ITA5_MOUSE
θ value	1.85459e-37 (rank : 23)	NC score	0.778618 (rank : 23)
Query Neighborhood Hits	78	Target Neighborhood Hits	41	Shared Neighborhood Hits	35
SwissProt Accessions	P11688	Gene names	Itga5
Domain Architecture
Description	Integrin alpha-5 precursor (Fibronectin receptor subunit alpha) (Integrin alpha-F) (VLA-5) (CD49e antigen) [Contains: Integrin alpha-5 heavy chain; Integrin alpha-5 light chain].

ITAV_HUMAN
θ value	1.57e-36 (rank : 24)	NC score	0.775737 (rank : 25)
Query Neighborhood Hits	78	Target Neighborhood Hits	39	Shared Neighborhood Hits	35
SwissProt Accessions	P06756	Gene names	ITGAV, VNRA
Domain Architecture
Description	Integrin alpha-V precursor (Vitronectin receptor subunit alpha) (CD51 antigen) [Contains: Integrin alpha-V heavy chain; Integrin alpha-V light chain].

ITA5_HUMAN
θ value	1.73584e-35 (rank : 25)	NC score	0.777954 (rank : 24)
Query Neighborhood Hits	78	Target Neighborhood Hits	44	Shared Neighborhood Hits	35
SwissProt Accessions	P08648, Q96HA5	Gene names	ITGA5, FNRA
Domain Architecture
Description	Integrin alpha-5 precursor (Fibronectin receptor subunit alpha) (Integrin alpha-F) (VLA-5) (CD49e antigen) [Contains: Integrin alpha-5 heavy chain; Integrin alpha-5 light chain].

ITA6_MOUSE
θ value	3.27365e-34 (rank : 26)	NC score	0.773461 (rank : 26)
Query Neighborhood Hits	78	Target Neighborhood Hits	41	Shared Neighborhood Hits	35
SwissProt Accessions	Q61739	Gene names	Itga6
Domain Architecture
Description	Integrin alpha-6 precursor (VLA-6) (CD49f antigen) [Contains: Integrin alpha-6 heavy chain; Integrin alpha-6 light chain].

ITA8_HUMAN
θ value	6.82597e-32 (rank : 27)	NC score	0.770471 (rank : 27)
Query Neighborhood Hits	78	Target Neighborhood Hits	45	Shared Neighborhood Hits	35
SwissProt Accessions	P53708, Q5VX94	Gene names	ITGA8
Domain Architecture
Description	Integrin alpha-8 precursor [Contains: Integrin alpha-8 heavy chain; Integrin alpha-8 light chain].

ITA7_MOUSE
θ value	2.59387e-31 (rank : 28)	NC score	0.762444 (rank : 32)
Query Neighborhood Hits	78	Target Neighborhood Hits	42	Shared Neighborhood Hits	35
SwissProt Accessions	Q61738, O88731, O88732, P70350, Q61737, Q61741	Gene names	Itga7
Domain Architecture
Description	Integrin alpha-7 precursor [Contains: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain].

ITA6_HUMAN
θ value	5.77852e-31 (rank : 29)	NC score	0.767880 (rank : 28)
Query Neighborhood Hits	78	Target Neighborhood Hits	47	Shared Neighborhood Hits	35
SwissProt Accessions	P23229, Q08443, Q14646, Q16508, Q9UN03	Gene names	ITGA6
Domain Architecture
Description	Integrin alpha-6 precursor (VLA-6) (CD49f antigen) [Contains: Integrin alpha-6 heavy chain; Integrin alpha-6 light chain].

ITA7_HUMAN
θ value	2.42779e-29 (rank : 30)	NC score	0.762514 (rank : 31)
Query Neighborhood Hits	78	Target Neighborhood Hits	47	Shared Neighborhood Hits	35
SwissProt Accessions	Q13683, O43197, Q9NY89, Q9UET0, Q9UEV2	Gene names	ITGA7
Domain Architecture
Description	Integrin alpha-7 precursor [Contains: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain].

ITA2B_HUMAN
θ value	9.2256e-29 (rank : 31)	NC score	0.767370 (rank : 29)
Query Neighborhood Hits	78	Target Neighborhood Hits	41	Shared Neighborhood Hits	35
SwissProt Accessions	P08514, O95366, Q14443	Gene names	ITGA2B, GP2B, ITGAB
Domain Architecture
Description	Integrin alpha-IIb precursor (Platelet membrane glycoprotein IIb) (GPalpha IIb) (GPIIb) (CD41 antigen) [Contains: Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain].

ITA2B_MOUSE
θ value	6.61148e-27 (rank : 32)	NC score	0.762848 (rank : 30)
Query Neighborhood Hits	78	Target Neighborhood Hits	45	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QUM0, Q64229, Q9Z2M0	Gene names	Itga2b
Domain Architecture
Description	Integrin alpha-IIb precursor (Platelet membrane glycoprotein IIb) (GPalpha IIb) (GPIIb) (CD41 antigen) [Contains: Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain].

MATN1_MOUSE
θ value	7.82807e-20 (rank : 33)	NC score	0.575979 (rank : 35)
Query Neighborhood Hits	78	Target Neighborhood Hits	186	Shared Neighborhood Hits	42
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

COEA1_HUMAN
θ value	2.97466e-19 (rank : 34)	NC score	0.402060 (rank : 46)
Query Neighborhood Hits	78	Target Neighborhood Hits	427	Shared Neighborhood Hits	41
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

MATN1_HUMAN
θ value	5.07402e-19 (rank : 35)	NC score	0.574616 (rank : 36)
Query Neighborhood Hits	78	Target Neighborhood Hits	191	Shared Neighborhood Hits	42
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

COEA1_MOUSE
θ value	1.63225e-17 (rank : 36)	NC score	0.410676 (rank : 42)
Query Neighborhood Hits	78	Target Neighborhood Hits	402	Shared Neighborhood Hits	41
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

COCA1_MOUSE
θ value	3.63628e-17 (rank : 37)	NC score	0.388423 (rank : 50)
Query Neighborhood Hits	78	Target Neighborhood Hits	467	Shared Neighborhood Hits	41
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

MATN2_HUMAN
θ value	6.20254e-17 (rank : 38)	NC score	0.334612 (rank : 53)
Query Neighborhood Hits	78	Target Neighborhood Hits	365	Shared Neighborhood Hits	43
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

VITRN_HUMAN
θ value	8.10077e-17 (rank : 39)	NC score	0.577842 (rank : 34)
Query Neighborhood Hits	78	Target Neighborhood Hits	63	Shared Neighborhood Hits	41
SwissProt Accessions	Q6UXI7, Q6P7T3, Q96DT1	Gene names	VIT
Domain Architecture	No domain graphic available
Description	Vitrin precursor.

COCA1_HUMAN
θ value	1.058e-16 (rank : 40)	NC score	0.390319 (rank : 49)
Query Neighborhood Hits	78	Target Neighborhood Hits	458	Shared Neighborhood Hits	42
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

MATN2_MOUSE
θ value	2.35696e-16 (rank : 41)	NC score	0.341834 (rank : 52)
Query Neighborhood Hits	78	Target Neighborhood Hits	356	Shared Neighborhood Hits	42
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

VITRN_MOUSE
θ value	6.85773e-16 (rank : 42)	NC score	0.583728 (rank : 33)
Query Neighborhood Hits	78	Target Neighborhood Hits	68	Shared Neighborhood Hits	41
SwissProt Accessions	Q8VHI5, Q3TZ47, Q8BQ41, Q8K047, Q9CYZ1	Gene names	Vit
Domain Architecture	No domain graphic available
Description	Vitrin precursor.

MATN3_MOUSE
θ value	2.60593e-15 (rank : 43)	NC score	0.405120 (rank : 45)
Query Neighborhood Hits	78	Target Neighborhood Hits	261	Shared Neighborhood Hits	41
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

MATN3_HUMAN
θ value	5.8054e-15 (rank : 44)	NC score	0.407186 (rank : 44)
Query Neighborhood Hits	78	Target Neighborhood Hits	268	Shared Neighborhood Hits	41
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

MATN4_HUMAN
θ value	9.90251e-15 (rank : 45)	NC score	0.394718 (rank : 48)
Query Neighborhood Hits	78	Target Neighborhood Hits	287	Shared Neighborhood Hits	42
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

MATN4_MOUSE
θ value	6.41864e-14 (rank : 46)	NC score	0.410308 (rank : 43)
Query Neighborhood Hits	78	Target Neighborhood Hits	277	Shared Neighborhood Hits	42
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

COCH_HUMAN
θ value	1.09485e-13 (rank : 47)	NC score	0.557242 (rank : 38)
Query Neighborhood Hits	78	Target Neighborhood Hits	51	Shared Neighborhood Hits	41
SwissProt Accessions	O43405	Gene names	COCH, COCH5B2
Domain Architecture
Description	Cochlin precursor (COCH-5B2).

COCH_MOUSE
θ value	3.18553e-13 (rank : 48)	NC score	0.557629 (rank : 37)
Query Neighborhood Hits	78	Target Neighborhood Hits	51	Shared Neighborhood Hits	41
SwissProt Accessions	Q62507, Q3TAF5, Q9QWK6	Gene names	Coch
Domain Architecture
Description	Cochlin precursor (COCH-5B2).

CO7A1_HUMAN
θ value	8.67504e-11 (rank : 49)	NC score	0.254817 (rank : 56)
Query Neighborhood Hits	78	Target Neighborhood Hits	807	Shared Neighborhood Hits	41
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

COKA1_HUMAN
θ value	4.30538e-10 (rank : 50)	NC score	0.397204 (rank : 47)
Query Neighborhood Hits	78	Target Neighborhood Hits	403	Shared Neighborhood Hits	41
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

CO6A3_HUMAN
θ value	1.17247e-07 (rank : 51)	NC score	0.387322 (rank : 51)
Query Neighborhood Hits	78	Target Neighborhood Hits	317	Shared Neighborhood Hits	41
SwissProt Accessions	P12111, Q16501	Gene names	COL6A3
Domain Architecture
Description	Collagen alpha-3(VI) chain precursor.

PHLD1_HUMAN
θ value	2.61198e-07 (rank : 52)	NC score	0.481447 (rank : 40)
Query Neighborhood Hits	78	Target Neighborhood Hits	48	Shared Neighborhood Hits	35
SwissProt Accessions	P80108, Q15128	Gene names	GPLD1, PIGPLD1
Domain Architecture
Description	Phosphatidylinositol-glycan-specific phospholipase D 1 precursor (EC 3.1.4.50) (PI-G PLD) (Glycoprotein phospholipase D) (Glycosyl- phosphatidylinositol-specific phospholipase D).

PHLD_MOUSE
θ value	9.92553e-07 (rank : 53)	NC score	0.493380 (rank : 39)
Query Neighborhood Hits	78	Target Neighborhood Hits	38	Shared Neighborhood Hits	35
SwissProt Accessions	O70362	Gene names	Gpld1
Domain Architecture
Description	Phosphatidylinositol-glycan-specific phospholipase D 1 precursor (EC 3.1.4.50) (PI-G PLD) (Glycoprotein phospholipase D) (Glycosyl- phosphatidylinositol-specific phospholipase D).

VWF_HUMAN
θ value	6.43352e-06 (rank : 54)	NC score	0.291658 (rank : 55)
Query Neighborhood Hits	78	Target Neighborhood Hits	396	Shared Neighborhood Hits	41
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

VWF_MOUSE
θ value	1.43324e-05 (rank : 55)	NC score	0.315262 (rank : 54)
Query Neighborhood Hits	78	Target Neighborhood Hits	381	Shared Neighborhood Hits	41
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

CO6A2_MOUSE
θ value	2.44474e-05 (rank : 56)	NC score	0.223160 (rank : 57)
Query Neighborhood Hits	78	Target Neighborhood Hits	260	Shared Neighborhood Hits	39
SwissProt Accessions	Q02788, Q05505	Gene names	Col6a2
Domain Architecture
Description	Collagen alpha-2(VI) chain precursor.

PHLD2_HUMAN
θ value	0.000158464 (rank : 57)	NC score	0.462737 (rank : 41)
Query Neighborhood Hits	78	Target Neighborhood Hits	44	Shared Neighborhood Hits	35
SwissProt Accessions	Q15127	Gene names	GPLD2, PIGPLD2
Domain Architecture
Description	Phosphatidylinositol-glycan-specific phospholipase D 2 precursor (EC 3.1.4.50) (PI-G PLD) (Glycoprotein phospholipase D) (Glycosyl- phosphatidylinositol-specific phospholipase D).

CO6A1_HUMAN
θ value	0.000786445 (rank : 58)	NC score	0.196686 (rank : 60)
Query Neighborhood Hits	78	Target Neighborhood Hits	264	Shared Neighborhood Hits	41
SwissProt Accessions	P12109, O00117, O00118, Q14040, Q14041, Q16258	Gene names	COL6A1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

CO6A2_HUMAN
θ value	0.000786445 (rank : 59)	NC score	0.220346 (rank : 58)
Query Neighborhood Hits	78	Target Neighborhood Hits	249	Shared Neighborhood Hits	38
SwissProt Accessions	P12110, Q13909, Q13910, Q13911, Q14049, Q16259, Q16597, Q9UML3	Gene names	COL6A2
Domain Architecture
Description	Collagen alpha-2(VI) chain precursor.

CO6A1_MOUSE
θ value	0.0961366 (rank : 60)	NC score	0.200346 (rank : 59)
Query Neighborhood Hits	78	Target Neighborhood Hits	241	Shared Neighborhood Hits	43
SwissProt Accessions	Q04857	Gene names	Col6a1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

ITIH3_HUMAN
θ value	0.21417 (rank : 61)	NC score	0.020161 (rank : 75)
Query Neighborhood Hits	78	Target Neighborhood Hits	38	Shared Neighborhood Hits	6
SwissProt Accessions	Q06033, Q99085	Gene names	ITIH3
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H3 precursor (ITI heavy chain H3) (Inter-alpha-inhibitor heavy chain 3) (Serum-derived hyaluronan-associated protein) (SHAP).

JIP4_HUMAN
θ value	0.279714 (rank : 62)	NC score	0.016405 (rank : 78)
Query Neighborhood Hits	78	Target Neighborhood Hits	585	Shared Neighborhood Hits	4
SwissProt Accessions	O60271, O60905, Q3KQU8, Q3MKM7, Q86WC7, Q86WC8, Q8IZX7, Q96II0, Q9H811	Gene names	SPAG9, HSS, KIAA0516, MAPK8IP4, SYD1
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (Human lung cancer protein 6) (HLC-6) (Proliferation-inducing protein 6) (Sperm-specific protein) (Sperm surface protein) (Protein highly expressed in testis) (PHET) (Sunday driver 1).

PHC3_MOUSE
θ value	0.62314 (rank : 63)	NC score	0.014833 (rank : 79)
Query Neighborhood Hits	78	Target Neighborhood Hits	194	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CHP6, Q3TLV5	Gene names	Phc3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3.

DUS8_MOUSE
θ value	1.06291 (rank : 64)	NC score	0.008658 (rank : 83)
Query Neighborhood Hits	78	Target Neighborhood Hits	119	Shared Neighborhood Hits	3
SwissProt Accessions	O09112	Gene names	Dusp8, Nttp1
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Neuronal tyrosine threonine phosphatase 1).

ITIH4_HUMAN
θ value	1.81305 (rank : 65)	NC score	0.027599 (rank : 74)
Query Neighborhood Hits	78	Target Neighborhood Hits	46	Shared Neighborhood Hits	12
SwissProt Accessions	Q14624, Q15135, Q9P190, Q9UQ54	Gene names	ITIH4, IHRP, ITIHL1, PK120
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H4 precursor (ITI heavy chain H4) (Inter-alpha-inhibitor heavy chain 4) (Inter-alpha-trypsin inhibitor family heavy chain-related protein) (IHRP) (Plasma kallikrein sensitive glycoprotein 120) (PK-120) (GP120) [Contains: 70 kDa inter-alpha-trypsin inhibitor heavy chain H4; 35 kDa inter-alpha- trypsin inhibitor heavy chain H4].

PHC3_HUMAN
θ value	1.81305 (rank : 66)	NC score	0.012889 (rank : 80)
Query Neighborhood Hits	78	Target Neighborhood Hits	218	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NDX5, Q5HYF0, Q6NSG2, Q8NFT7, Q8NFZ1, Q8TBM2, Q9H971, Q9H9I4	Gene names	PHC3, EDR3, PH3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3 (hPH3) (Homolog of polyhomeotic 3) (Early development regulatory protein 3).

DUS8_HUMAN
θ value	2.36792 (rank : 67)	NC score	0.007421 (rank : 84)
Query Neighborhood Hits	78	Target Neighborhood Hits	161	Shared Neighborhood Hits	3
SwissProt Accessions	Q13202	Gene names	DUSP8, VH5
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH-5).

JIP4_MOUSE
θ value	2.36792 (rank : 68)	NC score	0.016741 (rank : 77)
Query Neighborhood Hits	78	Target Neighborhood Hits	593	Shared Neighborhood Hits	4
SwissProt Accessions	Q58A65, Q3UH77, Q3UHF0, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2	Gene names	Spag9, Jip4, Jsap2, Kiaa0516, Mapk8ip4
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (JNK/SAPK-associated protein 2) (JSAP2).

DHX29_HUMAN
θ value	3.0926 (rank : 69)	NC score	0.004184 (rank : 87)
Query Neighborhood Hits	78	Target Neighborhood Hits	144	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z478, O75549, Q63HN0, Q63HN3, Q8IWW2, Q8N3A1, Q9UMH2	Gene names	DHX29
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX29 (EC 3.6.1.-) (DEAH box protein 29) (Nucleic acid helicase DDXx).

GCSP_HUMAN
θ value	5.27518 (rank : 70)	NC score	0.009881 (rank : 81)
Query Neighborhood Hits	78	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	P23378	Gene names	GLDC, GCSP
Domain Architecture
Description	Glycine dehydrogenase [decarboxylating], mitochondrial precursor (EC 1.4.4.2) (Glycine decarboxylase) (Glycine cleavage system P- protein).

HORN_HUMAN
θ value	5.27518 (rank : 71)	NC score	0.003269 (rank : 89)
Query Neighborhood Hits	78	Target Neighborhood Hits	206	Shared Neighborhood Hits	2
SwissProt Accessions	Q86YZ3	Gene names	HRNR, S100A18
Domain Architecture	No domain graphic available
Description	Hornerin.

ANGT_HUMAN
θ value	6.88961 (rank : 72)	NC score	0.002224 (rank : 90)
Query Neighborhood Hits	78	Target Neighborhood Hits	81	Shared Neighborhood Hits	2
SwissProt Accessions	P01019, Q16358, Q16359, Q96F91	Gene names	AGT, SERPINA8
Domain Architecture
Description	Angiotensinogen precursor [Contains: Angiotensin-1 (Angiotensin I) (Ang I); Angiotensin-2 (Angiotensin II) (Ang II); Angiotensin-3 (Angiotensin III) (Ang III) (Des-Asp[1]-angiotensin II)].

ITIH3_MOUSE
θ value	6.88961 (rank : 73)	NC score	0.017500 (rank : 76)
Query Neighborhood Hits	78	Target Neighborhood Hits	34	Shared Neighborhood Hits	9
SwissProt Accessions	Q61704	Gene names	Itih3
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H3 precursor (ITI heavy chain H3) (Inter-alpha-inhibitor heavy chain 3).

GCSP_MOUSE
θ value	8.99809 (rank : 74)	NC score	0.008686 (rank : 82)
Query Neighborhood Hits	78	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q91W43	Gene names	Gldc
Domain Architecture
Description	Glycine dehydrogenase [decarboxylating], mitochondrial precursor (EC 1.4.4.2) (Glycine decarboxylase) (Glycine cleavage system P- protein).

IKKE_HUMAN
θ value	8.99809 (rank : 75)	NC score	-0.005818 (rank : 91)
Query Neighborhood Hits	78	Target Neighborhood Hits	837	Shared Neighborhood Hits	2
SwissProt Accessions	Q14164	Gene names	IKBKE, IKKE, IKKI, KIAA0151
Domain Architecture
Description	Inhibitor of nuclear factor kappa-B kinase epsilon subunit (EC 2.7.11.10) (I kappa-B kinase epsilon) (IkBKE) (IKK-epsilon) (IKK- E) (Inducible I kappa-B kinase) (IKK-i).

PAPS1_HUMAN
θ value	8.99809 (rank : 76)	NC score	0.005430 (rank : 85)
Query Neighborhood Hits	78	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	O43252, O43841, O75332, Q96FB1, Q96TF4, Q9P1P9, Q9UE98	Gene names	PAPSS1, ATPSK1, PAPSS
Domain Architecture
Description	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 (PAPS synthetase 1) (PAPSS 1) (Sulfurylase kinase 1) (SK1) (SK 1) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (Sulfate adenylate transferase) (SAT) (ATP-sulfurylase); Adenylyl-sulfate kinase (EC 2.7.1.25) (Adenylylsulfate 3'-phosphotransferase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (3'- phosphoadenosine-5'-phosphosulfate synthetase)].

PAPS1_MOUSE
θ value	8.99809 (rank : 77)	NC score	0.005429 (rank : 86)
Query Neighborhood Hits	78	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q60967	Gene names	Papss1, Asapk, Atpsk1, Papss
Domain Architecture
Description	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 (PAPS synthetase 1) (PAPSS 1) (Sulfurylase kinase 1) (SK1) (SK 1) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (Sulfate adenylate transferase) (SAT) (ATP-sulfurylase); Adenylyl-sulfate kinase (EC 2.7.1.25) (Adenylylsulfate 3'-phosphotransferase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (3'- phosphoadenosine-5'-phosphosulfate synthetase)].

SETX_HUMAN
θ value	8.99809 (rank : 78)	NC score	0.004061 (rank : 88)
Query Neighborhood Hits	78	Target Neighborhood Hits	368	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

ANTR1_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.061156 (rank : 62)
Query Neighborhood Hits	78	Target Neighborhood Hits	128	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H6X2, Q96P02, Q9NVP3	Gene names	ANTXR1, ATR, TEM8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

ANTR1_MOUSE
θ value	θ > 10 (rank : 80)	NC score	0.058168 (rank : 63)
Query Neighborhood Hits	78	Target Neighborhood Hits	143	Shared Neighborhood Hits	11
SwissProt Accessions	Q9CZ52	Gene names	Antxr1, Atr, Tem8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

ANTR2_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.066188 (rank : 61)
Query Neighborhood Hits	78	Target Neighborhood Hits	34	Shared Neighborhood Hits	18
SwissProt Accessions	P58335, Q59E98, Q5JPE9, Q86UI1, Q8N4J8, Q8NB13, Q96NC7	Gene names	ANTXR2, CMG2
Domain Architecture
Description	Anthrax toxin receptor 2 precursor (Capillary morphogenesis gene 2 protein) (CMG-2).

CFAB_MOUSE
θ value	θ > 10 (rank : 82)	NC score	0.053019 (rank : 69)
Query Neighborhood Hits	78	Target Neighborhood Hits	262	Shared Neighborhood Hits	27
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CO9A1_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.051682 (rank : 71)
Query Neighborhood Hits	78	Target Neighborhood Hits	420	Shared Neighborhood Hits	11
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

CO9A1_MOUSE
θ value	θ > 10 (rank : 84)	NC score	0.051815 (rank : 70)
Query Neighborhood Hits	78	Target Neighborhood Hits	477	Shared Neighborhood Hits	11
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

CO9A3_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.053652 (rank : 68)
Query Neighborhood Hits	78	Target Neighborhood Hits	361	Shared Neighborhood Hits	11
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

COGA1_HUMAN
θ value	θ > 10 (rank : 86)	NC score	0.050944 (rank : 72)
Query Neighborhood Hits	78	Target Neighborhood Hits	345	Shared Neighborhood Hits	11
SwissProt Accessions	Q07092	Gene names	COL16A1
Domain Architecture
Description	Collagen alpha-1(XVI) chain precursor.

COJA1_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.055808 (rank : 67)
Query Neighborhood Hits	78	Target Neighborhood Hits	323	Shared Neighborhood Hits	11
SwissProt Accessions	Q14993, Q00559, Q05850, Q12885, Q13676, Q5JUF0, Q5T424, Q9H572, Q9NPZ2, Q9NQP2	Gene names	COL19A1
Domain Architecture
Description	Collagen alpha-1(XIX) chain precursor (Collagen alpha-1(Y) chain).

CONA1_HUMAN
θ value	θ > 10 (rank : 88)	NC score	0.056669 (rank : 66)
Query Neighborhood Hits	78	Target Neighborhood Hits	281	Shared Neighborhood Hits	11
SwissProt Accessions	Q86Y22, Q8IVR4, Q9NT93	Gene names	COL23A1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

FINC_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.057398 (rank : 64)
Query Neighborhood Hits	78	Target Neighborhood Hits	302	Shared Neighborhood Hits	7
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

FINC_MOUSE
θ value	θ > 10 (rank : 90)	NC score	0.057202 (rank : 65)
Query Neighborhood Hits	78	Target Neighborhood Hits	309	Shared Neighborhood Hits	9
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

MARCO_MOUSE
θ value	θ > 10 (rank : 91)	NC score	0.050070 (rank : 73)
Query Neighborhood Hits	78	Target Neighborhood Hits	242	Shared Neighborhood Hits	11
SwissProt Accessions	Q60754	Gene names	Marco
Domain Architecture
Description	Macrophage receptor MARCO (Macrophage receptor with collagenous structure).

Hits sorted by NC score

ITAM_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	78	Target Neighborhood Hits	78	Shared Neighborhood Hits	78
SwissProt Accessions	P11215	Gene names	ITGAM, CD11B, CR3A
Domain Architecture
Description	Integrin alpha-M precursor (Cell surface glycoprotein MAC-1 alpha subunit) (CR-3 alpha chain) (Leukocyte adhesion receptor MO1) (Neutrophil adherence receptor) (CD11b antigen).

ITAM_MOUSE
NC score	0.996836 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	78	Target Neighborhood Hits	77	Shared Neighborhood Hits	65
SwissProt Accessions	P05555, Q8CA73	Gene names	Itgam
Domain Architecture
Description	Integrin alpha-M precursor (Cell surface glycoprotein MAC-1 alpha subunit) (CR-3 alpha chain) (Leukocyte adhesion receptor MO1) (CD11b antigen).

ITAX_MOUSE
NC score	0.995859 (rank : 3)	θ value	0 (rank : 6)
Query Neighborhood Hits	78	Target Neighborhood Hits	69	Shared Neighborhood Hits	60
SwissProt Accessions	Q9QXH4	Gene names	Itgax
Domain Architecture
Description	Integrin alpha-X precursor (Leukocyte adhesion glycoprotein p150,95 alpha chain) (Leukocyte adhesion receptor p150,95) (CD11c antigen).

ITAD_MOUSE
NC score	0.995100 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	78	Target Neighborhood Hits	85	Shared Neighborhood Hits	60
SwissProt Accessions	Q3V0T4	Gene names	Itgad
Domain Architecture	No domain graphic available
Description	Integrin alpha-D precursor (CD11d antigen).

ITAD_HUMAN
NC score	0.994244 (rank : 5)	θ value	0 (rank : 1)
Query Neighborhood Hits	78	Target Neighborhood Hits	67	Shared Neighborhood Hits	59
SwissProt Accessions	Q13349, Q15575, Q15576	Gene names	ITGAD
Domain Architecture
Description	Integrin alpha-D precursor (Leukointegrin alpha D) (ADB2) (CD11d antigen).

ITAX_HUMAN
NC score	0.994212 (rank : 6)	θ value	0 (rank : 5)
Query Neighborhood Hits	78	Target Neighborhood Hits	81	Shared Neighborhood Hits	61
SwissProt Accessions	P20702, Q8IVA6	Gene names	ITGAX, CD11C
Domain Architecture
Description	Integrin alpha-X precursor (Leukocyte adhesion glycoprotein p150,95 alpha chain) (Leukocyte adhesion receptor p150,95) (Leu M5) (CD11c antigen).

ITAL_HUMAN
NC score	0.977998 (rank : 7)	θ value	1.16101e-156 (rank : 7)
Query Neighborhood Hits	78	Target Neighborhood Hits	71	Shared Neighborhood Hits	60
SwissProt Accessions	P20701, O43746, Q45H73, Q9UBC8	Gene names	ITGAL, CD11A
Domain Architecture
Description	Integrin alpha-L precursor (Leukocyte adhesion glycoprotein LFA-1 alpha chain) (LFA-1A) (Leukocyte function-associated molecule 1 alpha chain) (CD11a antigen).

ITAL_MOUSE
NC score	0.977744 (rank : 8)	θ value	2.18956e-155 (rank : 8)
Query Neighborhood Hits	78	Target Neighborhood Hits	68	Shared Neighborhood Hits	60
SwissProt Accessions	P24063	Gene names	Itgal, Lfa-1, Ly-15
Domain Architecture
Description	Integrin alpha-L precursor (Leukocyte adhesion glycoprotein LFA-1 alpha chain) (LFA-1A) (Leukocyte function-associated molecule 1 alpha chain) (Lymphocyte antigen Ly-15) (CD11a antigen).

ITAE_HUMAN
NC score	0.962048 (rank : 9)	θ value	3.42535e-108 (rank : 9)
Query Neighborhood Hits	78	Target Neighborhood Hits	77	Shared Neighborhood Hits	60
SwissProt Accessions	P38570, Q9NZU9	Gene names	ITGAE
Domain Architecture
Description	Integrin alpha-E precursor (Mucosal lymphocyte 1 antigen) (HML-1 antigen) (Integrin alpha-IEL) (CD103 antigen) [Contains: Integrin alpha-E light chain; Integrin alpha-E heavy chain].

ITAE_MOUSE
NC score	0.961314 (rank : 10)	θ value	1.48926e-103 (rank : 10)
Query Neighborhood Hits	78	Target Neighborhood Hits	73	Shared Neighborhood Hits	60
SwissProt Accessions	Q60677	Gene names	Itgae
Domain Architecture
Description	Integrin alpha-E precursor (Integrin alpha M290) (CD103 antigen) [Contains: Integrin alpha-E light chain; Integrin alpha-E heavy chain].

ITA10_HUMAN
NC score	0.952443 (rank : 11)	θ value	1.22112e-97 (rank : 13)
Query Neighborhood Hits	78	Target Neighborhood Hits	67	Shared Neighborhood Hits	58
SwissProt Accessions	O75578, Q6UXJ6, Q9UHZ8	Gene names	ITGA10
Domain Architecture
Description	Integrin alpha-10 precursor.

ITA1_HUMAN
NC score	0.952221 (rank : 12)	θ value	4.79078e-102 (rank : 11)
Query Neighborhood Hits	78	Target Neighborhood Hits	75	Shared Neighborhood Hits	59
SwissProt Accessions	P56199	Gene names	ITGA1
Domain Architecture	No domain graphic available
Description	Integrin alpha-1 (Laminin and collagen receptor) (VLA-1) (CD49a antigen).

ITA11_HUMAN
NC score	0.950958 (rank : 13)	θ value	4.95767e-99 (rank : 12)
Query Neighborhood Hits	78	Target Neighborhood Hits	70	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UKX5, Q8WYI8, Q9UKQ1	Gene names	ITGA11
Domain Architecture
Description	Integrin alpha-11 precursor.

ITA11_MOUSE
NC score	0.948418 (rank : 14)	θ value	8.19079e-94 (rank : 16)
Query Neighborhood Hits	78	Target Neighborhood Hits	70	Shared Neighborhood Hits	60
SwissProt Accessions	P61622	Gene names	Itga11
Domain Architecture
Description	Integrin alpha-11 precursor.

ITA2_MOUSE
NC score	0.947758 (rank : 15)	θ value	2.08291e-97 (rank : 14)
Query Neighborhood Hits	78	Target Neighborhood Hits	70	Shared Neighborhood Hits	58
SwissProt Accessions	Q62469, Q62163	Gene names	Itga2
Domain Architecture
Description	Integrin alpha-2 precursor (Platelet membrane glycoprotein Ia) (GPIa) (Collagen receptor) (VLA-2 alpha chain) (CD49b antigen).

ITA2_HUMAN
NC score	0.946551 (rank : 16)	θ value	1.49272e-95 (rank : 15)
Query Neighborhood Hits	78	Target Neighborhood Hits	64	Shared Neighborhood Hits	58
SwissProt Accessions	P17301, Q14595	Gene names	ITGA2
Domain Architecture
Description	Integrin alpha-2 precursor (Platelet membrane glycoprotein Ia) (GPIa) (Collagen receptor) (VLA-2 alpha chain) (CD49b antigen).

ITA9_HUMAN
NC score	0.845771 (rank : 17)	θ value	1.91031e-50 (rank : 19)
Query Neighborhood Hits	78	Target Neighborhood Hits	47	Shared Neighborhood Hits	35
SwissProt Accessions	Q13797, Q14638	Gene names	ITGA9
Domain Architecture
Description	Integrin alpha-9 precursor (Integrin alpha-RLC).

ITA4_MOUSE
NC score	0.843711 (rank : 18)	θ value	1.66964e-54 (rank : 17)
Query Neighborhood Hits	78	Target Neighborhood Hits	48	Shared Neighborhood Hits	35
SwissProt Accessions	Q00651	Gene names	Itga4
Domain Architecture
Description	Integrin alpha-4 precursor (Integrin alpha-IV) (VLA-4) (Lymphocyte Peyer patch adhesion molecules subunit alpha) (LPAM subunit alpha) (CD49d antigen).

ITA4_HUMAN
NC score	0.839780 (rank : 19)	θ value	1.01294e-51 (rank : 18)
Query Neighborhood Hits	78	Target Neighborhood Hits	45	Shared Neighborhood Hits	35
SwissProt Accessions	P13612	Gene names	ITGA4
Domain Architecture
Description	Integrin alpha-4 precursor (Integrin alpha-IV) (VLA-4) (CD49d antigen).

ITA3_MOUSE
NC score	0.805944 (rank : 20)	θ value	1.12253e-42 (rank : 20)
Query Neighborhood Hits	78	Target Neighborhood Hits	54	Shared Neighborhood Hits	35
SwissProt Accessions	Q62470, Q08441, Q08442	Gene names	Itga3
Domain Architecture
Description	Integrin alpha-3 precursor (Galactoprotein B3) (GAPB3) (VLA-3 alpha chain) (CD49c antigen) [Contains: Integrin alpha-3 heavy chain; Integrin alpha-3 light chain].

ITA3_HUMAN
NC score	0.805001 (rank : 21)	θ value	9.83387e-39 (rank : 21)
Query Neighborhood Hits	78	Target Neighborhood Hits	42	Shared Neighborhood Hits	35
SwissProt Accessions	P26006	Gene names	ITGA3
Domain Architecture
Description	Integrin alpha-3 precursor (Galactoprotein B3) (GAPB3) (VLA-3 alpha chain) (FRP-2) (CD49c antigen) [Contains: Integrin alpha-3 heavy chain; Integrin alpha-3 light chain].

ITAV_MOUSE
NC score	0.780182 (rank : 22)	θ value	8.32485e-38 (rank : 22)
Query Neighborhood Hits	78	Target Neighborhood Hits	43	Shared Neighborhood Hits	35
SwissProt Accessions	P43406	Gene names	Itgav
Domain Architecture
Description	Integrin alpha-V precursor (Vitronectin receptor subunit alpha) (CD51 antigen) [Contains: Integrin alpha-V heavy chain; Integrin alpha-V light chain].

ITA5_MOUSE
NC score	0.778618 (rank : 23)	θ value	1.85459e-37 (rank : 23)
Query Neighborhood Hits	78	Target Neighborhood Hits	41	Shared Neighborhood Hits	35
SwissProt Accessions	P11688	Gene names	Itga5
Domain Architecture
Description	Integrin alpha-5 precursor (Fibronectin receptor subunit alpha) (Integrin alpha-F) (VLA-5) (CD49e antigen) [Contains: Integrin alpha-5 heavy chain; Integrin alpha-5 light chain].

ITA5_HUMAN
NC score	0.777954 (rank : 24)	θ value	1.73584e-35 (rank : 25)
Query Neighborhood Hits	78	Target Neighborhood Hits	44	Shared Neighborhood Hits	35
SwissProt Accessions	P08648, Q96HA5	Gene names	ITGA5, FNRA
Domain Architecture
Description	Integrin alpha-5 precursor (Fibronectin receptor subunit alpha) (Integrin alpha-F) (VLA-5) (CD49e antigen) [Contains: Integrin alpha-5 heavy chain; Integrin alpha-5 light chain].

ITAV_HUMAN
NC score	0.775737 (rank : 25)	θ value	1.57e-36 (rank : 24)
Query Neighborhood Hits	78	Target Neighborhood Hits	39	Shared Neighborhood Hits	35
SwissProt Accessions	P06756	Gene names	ITGAV, VNRA
Domain Architecture
Description	Integrin alpha-V precursor (Vitronectin receptor subunit alpha) (CD51 antigen) [Contains: Integrin alpha-V heavy chain; Integrin alpha-V light chain].

ITA6_MOUSE
NC score	0.773461 (rank : 26)	θ value	3.27365e-34 (rank : 26)
Query Neighborhood Hits	78	Target Neighborhood Hits	41	Shared Neighborhood Hits	35
SwissProt Accessions	Q61739	Gene names	Itga6
Domain Architecture
Description	Integrin alpha-6 precursor (VLA-6) (CD49f antigen) [Contains: Integrin alpha-6 heavy chain; Integrin alpha-6 light chain].

ITA8_HUMAN
NC score	0.770471 (rank : 27)	θ value	6.82597e-32 (rank : 27)
Query Neighborhood Hits	78	Target Neighborhood Hits	45	Shared Neighborhood Hits	35
SwissProt Accessions	P53708, Q5VX94	Gene names	ITGA8
Domain Architecture
Description	Integrin alpha-8 precursor [Contains: Integrin alpha-8 heavy chain; Integrin alpha-8 light chain].

ITA6_HUMAN
NC score	0.767880 (rank : 28)	θ value	5.77852e-31 (rank : 29)
Query Neighborhood Hits	78	Target Neighborhood Hits	47	Shared Neighborhood Hits	35
SwissProt Accessions	P23229, Q08443, Q14646, Q16508, Q9UN03	Gene names	ITGA6
Domain Architecture
Description	Integrin alpha-6 precursor (VLA-6) (CD49f antigen) [Contains: Integrin alpha-6 heavy chain; Integrin alpha-6 light chain].

ITA2B_HUMAN
NC score	0.767370 (rank : 29)	θ value	9.2256e-29 (rank : 31)
Query Neighborhood Hits	78	Target Neighborhood Hits	41	Shared Neighborhood Hits	35
SwissProt Accessions	P08514, O95366, Q14443	Gene names	ITGA2B, GP2B, ITGAB
Domain Architecture
Description	Integrin alpha-IIb precursor (Platelet membrane glycoprotein IIb) (GPalpha IIb) (GPIIb) (CD41 antigen) [Contains: Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain].

ITA2B_MOUSE
NC score	0.762848 (rank : 30)	θ value	6.61148e-27 (rank : 32)
Query Neighborhood Hits	78	Target Neighborhood Hits	45	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QUM0, Q64229, Q9Z2M0	Gene names	Itga2b
Domain Architecture
Description	Integrin alpha-IIb precursor (Platelet membrane glycoprotein IIb) (GPalpha IIb) (GPIIb) (CD41 antigen) [Contains: Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain].

ITA7_HUMAN
NC score	0.762514 (rank : 31)	θ value	2.42779e-29 (rank : 30)
Query Neighborhood Hits	78	Target Neighborhood Hits	47	Shared Neighborhood Hits	35
SwissProt Accessions	Q13683, O43197, Q9NY89, Q9UET0, Q9UEV2	Gene names	ITGA7
Domain Architecture
Description	Integrin alpha-7 precursor [Contains: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain].

ITA7_MOUSE
NC score	0.762444 (rank : 32)	θ value	2.59387e-31 (rank : 28)
Query Neighborhood Hits	78	Target Neighborhood Hits	42	Shared Neighborhood Hits	35
SwissProt Accessions	Q61738, O88731, O88732, P70350, Q61737, Q61741	Gene names	Itga7
Domain Architecture
Description	Integrin alpha-7 precursor [Contains: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain].

VITRN_MOUSE
NC score	0.583728 (rank : 33)	θ value	6.85773e-16 (rank : 42)
Query Neighborhood Hits	78	Target Neighborhood Hits	68	Shared Neighborhood Hits	41
SwissProt Accessions	Q8VHI5, Q3TZ47, Q8BQ41, Q8K047, Q9CYZ1	Gene names	Vit
Domain Architecture	No domain graphic available
Description	Vitrin precursor.

VITRN_HUMAN
NC score	0.577842 (rank : 34)	θ value	8.10077e-17 (rank : 39)
Query Neighborhood Hits	78	Target Neighborhood Hits	63	Shared Neighborhood Hits	41
SwissProt Accessions	Q6UXI7, Q6P7T3, Q96DT1	Gene names	VIT
Domain Architecture	No domain graphic available
Description	Vitrin precursor.

MATN1_MOUSE
NC score	0.575979 (rank : 35)	θ value	7.82807e-20 (rank : 33)
Query Neighborhood Hits	78	Target Neighborhood Hits	186	Shared Neighborhood Hits	42
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN1_HUMAN
NC score	0.574616 (rank : 36)	θ value	5.07402e-19 (rank : 35)
Query Neighborhood Hits	78	Target Neighborhood Hits	191	Shared Neighborhood Hits	42
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

COCH_MOUSE
NC score	0.557629 (rank : 37)	θ value	3.18553e-13 (rank : 48)
Query Neighborhood Hits	78	Target Neighborhood Hits	51	Shared Neighborhood Hits	41
SwissProt Accessions	Q62507, Q3TAF5, Q9QWK6	Gene names	Coch
Domain Architecture
Description	Cochlin precursor (COCH-5B2).

COCH_HUMAN
NC score	0.557242 (rank : 38)	θ value	1.09485e-13 (rank : 47)
Query Neighborhood Hits	78	Target Neighborhood Hits	51	Shared Neighborhood Hits	41
SwissProt Accessions	O43405	Gene names	COCH, COCH5B2
Domain Architecture
Description	Cochlin precursor (COCH-5B2).

PHLD_MOUSE
NC score	0.493380 (rank : 39)	θ value	9.92553e-07 (rank : 53)
Query Neighborhood Hits	78	Target Neighborhood Hits	38	Shared Neighborhood Hits	35
SwissProt Accessions	O70362	Gene names	Gpld1
Domain Architecture
Description	Phosphatidylinositol-glycan-specific phospholipase D 1 precursor (EC 3.1.4.50) (PI-G PLD) (Glycoprotein phospholipase D) (Glycosyl- phosphatidylinositol-specific phospholipase D).

PHLD1_HUMAN
NC score	0.481447 (rank : 40)	θ value	2.61198e-07 (rank : 52)
Query Neighborhood Hits	78	Target Neighborhood Hits	48	Shared Neighborhood Hits	35
SwissProt Accessions	P80108, Q15128	Gene names	GPLD1, PIGPLD1
Domain Architecture
Description	Phosphatidylinositol-glycan-specific phospholipase D 1 precursor (EC 3.1.4.50) (PI-G PLD) (Glycoprotein phospholipase D) (Glycosyl- phosphatidylinositol-specific phospholipase D).

PHLD2_HUMAN
NC score	0.462737 (rank : 41)	θ value	0.000158464 (rank : 57)
Query Neighborhood Hits	78	Target Neighborhood Hits	44	Shared Neighborhood Hits	35
SwissProt Accessions	Q15127	Gene names	GPLD2, PIGPLD2
Domain Architecture
Description	Phosphatidylinositol-glycan-specific phospholipase D 2 precursor (EC 3.1.4.50) (PI-G PLD) (Glycoprotein phospholipase D) (Glycosyl- phosphatidylinositol-specific phospholipase D).

COEA1_MOUSE
NC score	0.410676 (rank : 42)	θ value	1.63225e-17 (rank : 36)
Query Neighborhood Hits	78	Target Neighborhood Hits	402	Shared Neighborhood Hits	41
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

MATN4_MOUSE
NC score	0.410308 (rank : 43)	θ value	6.41864e-14 (rank : 46)
Query Neighborhood Hits	78	Target Neighborhood Hits	277	Shared Neighborhood Hits	42
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

MATN3_HUMAN
NC score	0.407186 (rank : 44)	θ value	5.8054e-15 (rank : 44)
Query Neighborhood Hits	78	Target Neighborhood Hits	268	Shared Neighborhood Hits	41
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

MATN3_MOUSE
NC score	0.405120 (rank : 45)	θ value	2.60593e-15 (rank : 43)
Query Neighborhood Hits	78	Target Neighborhood Hits	261	Shared Neighborhood Hits	41
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

COEA1_HUMAN
NC score	0.402060 (rank : 46)	θ value	2.97466e-19 (rank : 34)
Query Neighborhood Hits	78	Target Neighborhood Hits	427	Shared Neighborhood Hits	41
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

COKA1_HUMAN
NC score	0.397204 (rank : 47)	θ value	4.30538e-10 (rank : 50)
Query Neighborhood Hits	78	Target Neighborhood Hits	403	Shared Neighborhood Hits	41
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

MATN4_HUMAN
NC score	0.394718 (rank : 48)	θ value	9.90251e-15 (rank : 45)
Query Neighborhood Hits	78	Target Neighborhood Hits	287	Shared Neighborhood Hits	42
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

COCA1_HUMAN
NC score	0.390319 (rank : 49)	θ value	1.058e-16 (rank : 40)
Query Neighborhood Hits	78	Target Neighborhood Hits	458	Shared Neighborhood Hits	42
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COCA1_MOUSE
NC score	0.388423 (rank : 50)	θ value	3.63628e-17 (rank : 37)
Query Neighborhood Hits	78	Target Neighborhood Hits	467	Shared Neighborhood Hits	41
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

CO6A3_HUMAN
NC score	0.387322 (rank : 51)	θ value	1.17247e-07 (rank : 51)
Query Neighborhood Hits	78	Target Neighborhood Hits	317	Shared Neighborhood Hits	41
SwissProt Accessions	P12111, Q16501	Gene names	COL6A3
Domain Architecture
Description	Collagen alpha-3(VI) chain precursor.

MATN2_MOUSE
NC score	0.341834 (rank : 52)	θ value	2.35696e-16 (rank : 41)
Query Neighborhood Hits	78	Target Neighborhood Hits	356	Shared Neighborhood Hits	42
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

MATN2_HUMAN
NC score	0.334612 (rank : 53)	θ value	6.20254e-17 (rank : 38)
Query Neighborhood Hits	78	Target Neighborhood Hits	365	Shared Neighborhood Hits	43
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

VWF_MOUSE
NC score	0.315262 (rank : 54)	θ value	1.43324e-05 (rank : 55)
Query Neighborhood Hits	78	Target Neighborhood Hits	381	Shared Neighborhood Hits	41
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

VWF_HUMAN
NC score	0.291658 (rank : 55)	θ value	6.43352e-06 (rank : 54)
Query Neighborhood Hits	78	Target Neighborhood Hits	396	Shared Neighborhood Hits	41
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

CO7A1_HUMAN
NC score	0.254817 (rank : 56)	θ value	8.67504e-11 (rank : 49)
Query Neighborhood Hits	78	Target Neighborhood Hits	807	Shared Neighborhood Hits	41
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

CO6A2_MOUSE
NC score	0.223160 (rank : 57)	θ value	2.44474e-05 (rank : 56)
Query Neighborhood Hits	78	Target Neighborhood Hits	260	Shared Neighborhood Hits	39
SwissProt Accessions	Q02788, Q05505	Gene names	Col6a2
Domain Architecture
Description	Collagen alpha-2(VI) chain precursor.

CO6A2_HUMAN
NC score	0.220346 (rank : 58)	θ value	0.000786445 (rank : 59)
Query Neighborhood Hits	78	Target Neighborhood Hits	249	Shared Neighborhood Hits	38
SwissProt Accessions	P12110, Q13909, Q13910, Q13911, Q14049, Q16259, Q16597, Q9UML3	Gene names	COL6A2
Domain Architecture
Description	Collagen alpha-2(VI) chain precursor.

CO6A1_MOUSE
NC score	0.200346 (rank : 59)	θ value	0.0961366 (rank : 60)
Query Neighborhood Hits	78	Target Neighborhood Hits	241	Shared Neighborhood Hits	43
SwissProt Accessions	Q04857	Gene names	Col6a1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

CO6A1_HUMAN
NC score	0.196686 (rank : 60)	θ value	0.000786445 (rank : 58)
Query Neighborhood Hits	78	Target Neighborhood Hits	264	Shared Neighborhood Hits	41
SwissProt Accessions	P12109, O00117, O00118, Q14040, Q14041, Q16258	Gene names	COL6A1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

ANTR2_HUMAN
NC score	0.066188 (rank : 61)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	78	Target Neighborhood Hits	34	Shared Neighborhood Hits	18
SwissProt Accessions	P58335, Q59E98, Q5JPE9, Q86UI1, Q8N4J8, Q8NB13, Q96NC7	Gene names	ANTXR2, CMG2
Domain Architecture
Description	Anthrax toxin receptor 2 precursor (Capillary morphogenesis gene 2 protein) (CMG-2).

ANTR1_HUMAN
NC score	0.061156 (rank : 62)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	78	Target Neighborhood Hits	128	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H6X2, Q96P02, Q9NVP3	Gene names	ANTXR1, ATR, TEM8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

ANTR1_MOUSE
NC score	0.058168 (rank : 63)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	78	Target Neighborhood Hits	143	Shared Neighborhood Hits	11
SwissProt Accessions	Q9CZ52	Gene names	Antxr1, Atr, Tem8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

FINC_HUMAN
NC score	0.057398 (rank : 64)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	78	Target Neighborhood Hits	302	Shared Neighborhood Hits	7
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

FINC_MOUSE
NC score	0.057202 (rank : 65)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	78	Target Neighborhood Hits	309	Shared Neighborhood Hits	9
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

CONA1_HUMAN
NC score	0.056669 (rank : 66)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	78	Target Neighborhood Hits	281	Shared Neighborhood Hits	11
SwissProt Accessions	Q86Y22, Q8IVR4, Q9NT93	Gene names	COL23A1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

COJA1_HUMAN
NC score	0.055808 (rank : 67)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	78	Target Neighborhood Hits	323	Shared Neighborhood Hits	11
SwissProt Accessions	Q14993, Q00559, Q05850, Q12885, Q13676, Q5JUF0, Q5T424, Q9H572, Q9NPZ2, Q9NQP2	Gene names	COL19A1
Domain Architecture
Description	Collagen alpha-1(XIX) chain precursor (Collagen alpha-1(Y) chain).

CO9A3_HUMAN
NC score	0.053652 (rank : 68)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	78	Target Neighborhood Hits	361	Shared Neighborhood Hits	11
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

CFAB_MOUSE
NC score	0.053019 (rank : 69)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	78	Target Neighborhood Hits	262	Shared Neighborhood Hits	27
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CO9A1_MOUSE
NC score	0.051815 (rank : 70)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	78	Target Neighborhood Hits	477	Shared Neighborhood Hits	11
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

CO9A1_HUMAN
NC score	0.051682 (rank : 71)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	78	Target Neighborhood Hits	420	Shared Neighborhood Hits	11
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

COGA1_HUMAN
NC score	0.050944 (rank : 72)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	78	Target Neighborhood Hits	345	Shared Neighborhood Hits	11
SwissProt Accessions	Q07092	Gene names	COL16A1
Domain Architecture
Description	Collagen alpha-1(XVI) chain precursor.

MARCO_MOUSE
NC score	0.050070 (rank : 73)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	78	Target Neighborhood Hits	242	Shared Neighborhood Hits	11
SwissProt Accessions	Q60754	Gene names	Marco
Domain Architecture
Description	Macrophage receptor MARCO (Macrophage receptor with collagenous structure).

ITIH4_HUMAN
NC score	0.027599 (rank : 74)	θ value	1.81305 (rank : 65)
Query Neighborhood Hits	78	Target Neighborhood Hits	46	Shared Neighborhood Hits	12
SwissProt Accessions	Q14624, Q15135, Q9P190, Q9UQ54	Gene names	ITIH4, IHRP, ITIHL1, PK120
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H4 precursor (ITI heavy chain H4) (Inter-alpha-inhibitor heavy chain 4) (Inter-alpha-trypsin inhibitor family heavy chain-related protein) (IHRP) (Plasma kallikrein sensitive glycoprotein 120) (PK-120) (GP120) [Contains: 70 kDa inter-alpha-trypsin inhibitor heavy chain H4; 35 kDa inter-alpha- trypsin inhibitor heavy chain H4].

ITIH3_HUMAN
NC score	0.020161 (rank : 75)	θ value	0.21417 (rank : 61)
Query Neighborhood Hits	78	Target Neighborhood Hits	38	Shared Neighborhood Hits	6
SwissProt Accessions	Q06033, Q99085	Gene names	ITIH3
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H3 precursor (ITI heavy chain H3) (Inter-alpha-inhibitor heavy chain 3) (Serum-derived hyaluronan-associated protein) (SHAP).

ITIH3_MOUSE
NC score	0.017500 (rank : 76)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	78	Target Neighborhood Hits	34	Shared Neighborhood Hits	9
SwissProt Accessions	Q61704	Gene names	Itih3
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H3 precursor (ITI heavy chain H3) (Inter-alpha-inhibitor heavy chain 3).

JIP4_MOUSE
NC score	0.016741 (rank : 77)	θ value	2.36792 (rank : 68)
Query Neighborhood Hits	78	Target Neighborhood Hits	593	Shared Neighborhood Hits	4
SwissProt Accessions	Q58A65, Q3UH77, Q3UHF0, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2	Gene names	Spag9, Jip4, Jsap2, Kiaa0516, Mapk8ip4
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (JNK/SAPK-associated protein 2) (JSAP2).

JIP4_HUMAN
NC score	0.016405 (rank : 78)	θ value	0.279714 (rank : 62)
Query Neighborhood Hits	78	Target Neighborhood Hits	585	Shared Neighborhood Hits	4
SwissProt Accessions	O60271, O60905, Q3KQU8, Q3MKM7, Q86WC7, Q86WC8, Q8IZX7, Q96II0, Q9H811	Gene names	SPAG9, HSS, KIAA0516, MAPK8IP4, SYD1
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (Human lung cancer protein 6) (HLC-6) (Proliferation-inducing protein 6) (Sperm-specific protein) (Sperm surface protein) (Protein highly expressed in testis) (PHET) (Sunday driver 1).

PHC3_MOUSE
NC score	0.014833 (rank : 79)	θ value	0.62314 (rank : 63)
Query Neighborhood Hits	78	Target Neighborhood Hits	194	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CHP6, Q3TLV5	Gene names	Phc3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3.

PHC3_HUMAN
NC score	0.012889 (rank : 80)	θ value	1.81305 (rank : 66)
Query Neighborhood Hits	78	Target Neighborhood Hits	218	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NDX5, Q5HYF0, Q6NSG2, Q8NFT7, Q8NFZ1, Q8TBM2, Q9H971, Q9H9I4	Gene names	PHC3, EDR3, PH3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3 (hPH3) (Homolog of polyhomeotic 3) (Early development regulatory protein 3).

GCSP_HUMAN
NC score	0.009881 (rank : 81)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	78	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	P23378	Gene names	GLDC, GCSP
Domain Architecture
Description	Glycine dehydrogenase [decarboxylating], mitochondrial precursor (EC 1.4.4.2) (Glycine decarboxylase) (Glycine cleavage system P- protein).

GCSP_MOUSE
NC score	0.008686 (rank : 82)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	78	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q91W43	Gene names	Gldc
Domain Architecture
Description	Glycine dehydrogenase [decarboxylating], mitochondrial precursor (EC 1.4.4.2) (Glycine decarboxylase) (Glycine cleavage system P- protein).

DUS8_MOUSE
NC score	0.008658 (rank : 83)	θ value	1.06291 (rank : 64)
Query Neighborhood Hits	78	Target Neighborhood Hits	119	Shared Neighborhood Hits	3
SwissProt Accessions	O09112	Gene names	Dusp8, Nttp1
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Neuronal tyrosine threonine phosphatase 1).

DUS8_HUMAN
NC score	0.007421 (rank : 84)	θ value	2.36792 (rank : 67)
Query Neighborhood Hits	78	Target Neighborhood Hits	161	Shared Neighborhood Hits	3
SwissProt Accessions	Q13202	Gene names	DUSP8, VH5
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH-5).

PAPS1_HUMAN
NC score	0.005430 (rank : 85)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	78	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	O43252, O43841, O75332, Q96FB1, Q96TF4, Q9P1P9, Q9UE98	Gene names	PAPSS1, ATPSK1, PAPSS
Domain Architecture
Description	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 (PAPS synthetase 1) (PAPSS 1) (Sulfurylase kinase 1) (SK1) (SK 1) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (Sulfate adenylate transferase) (SAT) (ATP-sulfurylase); Adenylyl-sulfate kinase (EC 2.7.1.25) (Adenylylsulfate 3'-phosphotransferase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (3'- phosphoadenosine-5'-phosphosulfate synthetase)].

PAPS1_MOUSE
NC score	0.005429 (rank : 86)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	78	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q60967	Gene names	Papss1, Asapk, Atpsk1, Papss
Domain Architecture
Description	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 (PAPS synthetase 1) (PAPSS 1) (Sulfurylase kinase 1) (SK1) (SK 1) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (Sulfate adenylate transferase) (SAT) (ATP-sulfurylase); Adenylyl-sulfate kinase (EC 2.7.1.25) (Adenylylsulfate 3'-phosphotransferase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (3'- phosphoadenosine-5'-phosphosulfate synthetase)].

DHX29_HUMAN
NC score	0.004184 (rank : 87)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	78	Target Neighborhood Hits	144	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z478, O75549, Q63HN0, Q63HN3, Q8IWW2, Q8N3A1, Q9UMH2	Gene names	DHX29
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX29 (EC 3.6.1.-) (DEAH box protein 29) (Nucleic acid helicase DDXx).

SETX_HUMAN
NC score	0.004061 (rank : 88)	θ value	8.99809 (rank : 78)
Query Neighborhood Hits	78	Target Neighborhood Hits	368	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

HORN_HUMAN
NC score	0.003269 (rank : 89)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	78	Target Neighborhood Hits	206	Shared Neighborhood Hits	2
SwissProt Accessions	Q86YZ3	Gene names	HRNR, S100A18
Domain Architecture	No domain graphic available
Description	Hornerin.

ANGT_HUMAN
NC score	0.002224 (rank : 90)	θ value	6.88961 (rank : 72)
Query Neighborhood Hits	78	Target Neighborhood Hits	81	Shared Neighborhood Hits	2
SwissProt Accessions	P01019, Q16358, Q16359, Q96F91	Gene names	AGT, SERPINA8
Domain Architecture
Description	Angiotensinogen precursor [Contains: Angiotensin-1 (Angiotensin I) (Ang I); Angiotensin-2 (Angiotensin II) (Ang II); Angiotensin-3 (Angiotensin III) (Ang III) (Des-Asp[1]-angiotensin II)].

IKKE_HUMAN
NC score	-0.005818 (rank : 91)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	78	Target Neighborhood Hits	837	Shared Neighborhood Hits	2
SwissProt Accessions	Q14164	Gene names	IKBKE, IKKE, IKKI, KIAA0151
Domain Architecture
Description	Inhibitor of nuclear factor kappa-B kinase epsilon subunit (EC 2.7.11.10) (I kappa-B kinase epsilon) (IkBKE) (IKK-epsilon) (IKK- E) (Inducible I kappa-B kinase) (IKK-i).