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Network neighborhood for query Sequence : DUS8_HUMAN

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DUS8_HUMAN
SwissProt Accessions	Q13202	Gene names	DUSP8, VH5
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH-5).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DUS8_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	161	Target Neighborhood Hits	161	Shared Neighborhood Hits	161
SwissProt Accessions	Q13202	Gene names	DUSP8, VH5
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH-5).

DUS8_MOUSE
θ value	0 (rank : 2)	NC score	0.984860 (rank : 2)
Query Neighborhood Hits	161	Target Neighborhood Hits	119	Shared Neighborhood Hits	83
SwissProt Accessions	O09112	Gene names	Dusp8, Nttp1
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Neuronal tyrosine threonine phosphatase 1).

DUS16_HUMAN
θ value	1.4755e-135 (rank : 3)	NC score	0.970683 (rank : 3)
Query Neighborhood Hits	161	Target Neighborhood Hits	112	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BY84, Q9C0G3	Gene names	DUSP16, KIAA1700, MKP7
Domain Architecture
Description	Dual specificity protein phosphatase 16 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 7) (MAP kinase phosphatase 7) (MKP-7).

DUS10_HUMAN
θ value	2.41655e-45 (rank : 4)	NC score	0.925276 (rank : 6)
Query Neighborhood Hits	161	Target Neighborhood Hits	64	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y6W6	Gene names	DUSP10, MKP5
Domain Architecture
Description	Dual specificity protein phosphatase 10 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 5) (MAP kinase phosphatase 5) (MKP-5).

DUS10_MOUSE
θ value	2.41655e-45 (rank : 5)	NC score	0.926174 (rank : 5)
Query Neighborhood Hits	161	Target Neighborhood Hits	62	Shared Neighborhood Hits	53
SwissProt Accessions	Q9ESS0, Q9CZY9	Gene names	Dusp10, Mkp5
Domain Architecture
Description	Dual specificity protein phosphatase 10 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 5) (MAP kinase phosphatase 5) (MKP-5).

DUS7_HUMAN
θ value	5.57106e-42 (rank : 6)	NC score	0.921407 (rank : 7)
Query Neighborhood Hits	161	Target Neighborhood Hits	69	Shared Neighborhood Hits	55
SwissProt Accessions	Q16829, Q8NFJ0	Gene names	DUSP7, PYST2
Domain Architecture
Description	Dual specificity protein phosphatase 7 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PYST2).

DUS1_MOUSE
θ value	1.62093e-41 (rank : 7)	NC score	0.911548 (rank : 12)
Query Neighborhood Hits	161	Target Neighborhood Hits	72	Shared Neighborhood Hits	57
SwissProt Accessions	P28563	Gene names	Dusp1, 3ch134, Mkp1, Ptpn10, Ptpn16
Domain Architecture
Description	Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase 3CH134) (Protein-tyrosine phosphatase ERP).

DUS4_HUMAN
θ value	2.76489e-41 (rank : 8)	NC score	0.910617 (rank : 14)
Query Neighborhood Hits	161	Target Neighborhood Hits	77	Shared Neighborhood Hits	55
SwissProt Accessions	Q13115, Q13524	Gene names	DUSP4, MKP2, VH2
Domain Architecture
Description	Dual specificity protein phosphatase 4 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 2) (MAP kinase phosphatase 2) (MKP-2) (Dual specificity protein phosphatase hVH2).

DUS6_HUMAN
θ value	2.34062e-40 (rank : 9)	NC score	0.918095 (rank : 8)
Query Neighborhood Hits	161	Target Neighborhood Hits	57	Shared Neighborhood Hits	50
SwissProt Accessions	Q16828, O75109, Q53Y75, Q9BSH6	Gene names	DUSP6, MKP3, PYST1
Domain Architecture
Description	Dual specificity protein phosphatase 6 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3) (Dual specificity protein phosphatase PYST1).

DUS6_MOUSE
θ value	5.21438e-40 (rank : 10)	NC score	0.917697 (rank : 10)
Query Neighborhood Hits	161	Target Neighborhood Hits	57	Shared Neighborhood Hits	50
SwissProt Accessions	Q9DBB1, Q542I5, Q9D7L4	Gene names	Dusp6, Mkp3
Domain Architecture
Description	Dual specificity protein phosphatase 6 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3).

DUS1_HUMAN
θ value	8.89434e-40 (rank : 11)	NC score	0.911100 (rank : 13)
Query Neighborhood Hits	161	Target Neighborhood Hits	73	Shared Neighborhood Hits	56
SwissProt Accessions	P28562, Q2V508	Gene names	DUSP1, CL100, MKP1, PTPN10, VH1
Domain Architecture
Description	Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase CL100) (Dual specificity protein phosphatase hVH1).

DUS4_MOUSE
θ value	7.52953e-39 (rank : 12)	NC score	0.909837 (rank : 15)
Query Neighborhood Hits	161	Target Neighborhood Hits	75	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BFV3	Gene names	Dusp4
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 4 (EC 3.1.3.48) (EC 3.1.3.16).

DUS9_HUMAN
θ value	1.28434e-38 (rank : 13)	NC score	0.928025 (rank : 4)
Query Neighborhood Hits	161	Target Neighborhood Hits	59	Shared Neighborhood Hits	53
SwissProt Accessions	Q99956	Gene names	DUSP9, MKP4
Domain Architecture
Description	Dual specificity protein phosphatase 9 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 4) (MAP kinase phosphatase 4) (MKP-4).

DUS2_HUMAN
θ value	5.39604e-37 (rank : 14)	NC score	0.917600 (rank : 11)
Query Neighborhood Hits	161	Target Neighborhood Hits	67	Shared Neighborhood Hits	55
SwissProt Accessions	Q05923	Gene names	DUSP2, PAC1
Domain Architecture
Description	Dual specificity protein phosphatase 2 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PAC-1).

DUS2_MOUSE
θ value	1.20211e-36 (rank : 15)	NC score	0.917996 (rank : 9)
Query Neighborhood Hits	161	Target Neighborhood Hits	86	Shared Neighborhood Hits	62
SwissProt Accessions	Q05922, Q60640	Gene names	Dusp2, Pac-1, Pac1
Domain Architecture
Description	Dual specificity protein phosphatase 2 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PAC-1).

DUS5_HUMAN
θ value	3.74554e-30 (rank : 16)	NC score	0.907603 (rank : 16)
Query Neighborhood Hits	161	Target Neighborhood Hits	82	Shared Neighborhood Hits	57
SwissProt Accessions	Q16690, Q12997	Gene names	DUSP5, VH3
Domain Architecture
Description	Dual specificity protein phosphatase 5 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH3).

SSH1_HUMAN
θ value	5.07402e-19 (rank : 17)	NC score	0.762828 (rank : 37)
Query Neighborhood Hits	161	Target Neighborhood Hits	164	Shared Neighborhood Hits	61
SwissProt Accessions	Q8WYL5, Q6P6C0, Q8N9A7, Q8WYL3, Q8WYL4, Q9P2P8	Gene names	SSH1, KIAA1298, SSH1L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (hSSH-1L).

STYX_MOUSE
θ value	3.28887e-18 (rank : 18)	NC score	0.854776 (rank : 21)
Query Neighborhood Hits	161	Target Neighborhood Hits	62	Shared Neighborhood Hits	56
SwissProt Accessions	Q60969, Q3TMA3, Q60970, Q9DCF8	Gene names	Styx
Domain Architecture
Description	Serine/threonine/tyrosine-interacting protein (Protein tyrosine phosphatase-like protein) (Phosphoserine/threonine/tyrosine interaction protein).

STYX_HUMAN
θ value	4.29542e-18 (rank : 19)	NC score	0.855961 (rank : 20)
Query Neighborhood Hits	161	Target Neighborhood Hits	60	Shared Neighborhood Hits	57
SwissProt Accessions	Q8WUJ0, Q99850	Gene names	STYX
Domain Architecture
Description	Serine/threonine/tyrosine-interacting protein (Protein tyrosine phosphatase-like protein).

SSH2_HUMAN
θ value	1.24977e-17 (rank : 20)	NC score	0.745087 (rank : 41)
Query Neighborhood Hits	161	Target Neighborhood Hits	140	Shared Neighborhood Hits	50
SwissProt Accessions	Q76I76, Q8TDB5, Q8WYL1, Q8WYL2, Q96F40, Q96H36, Q9C0D8	Gene names	SSH2, KIAA1725, SSH2L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (hSSH-2L).

SSH2_MOUSE
θ value	1.24977e-17 (rank : 21)	NC score	0.747872 (rank : 40)
Query Neighborhood Hits	161	Target Neighborhood Hits	119	Shared Neighborhood Hits	54
SwissProt Accessions	Q5SW75, Q3TDK8, Q3TYP8, Q3U2K3, Q5F268, Q5SW74, Q69ZC3, Q76I78	Gene names	Ssh2, Kiaa1725, Ssh2l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (mSSH-2L).

SSH3_MOUSE
θ value	2.13179e-17 (rank : 22)	NC score	0.777559 (rank : 32)
Query Neighborhood Hits	161	Target Neighborhood Hits	69	Shared Neighborhood Hits	52
SwissProt Accessions	Q8K330, Q3UDX0	Gene names	Ssh3, Ssh3l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 3 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-3L) (mSSH-3L).

DUS22_HUMAN
θ value	2.7842e-17 (rank : 23)	NC score	0.859904 (rank : 18)
Query Neighborhood Hits	161	Target Neighborhood Hits	58	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NRW4, Q59GW2, Q5VWR2, Q96AR1	Gene names	DUSP22, JSP1, MKPX
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 22 (EC 3.1.3.48) (EC 3.1.3.16) (JNK-stimulatory phosphatase-1) (JSP-1) (Mitogen-activated protein kinase phosphatase x) (LMW-DSP2).

DUS18_HUMAN
θ value	4.74913e-17 (rank : 24)	NC score	0.832876 (rank : 27)
Query Neighborhood Hits	161	Target Neighborhood Hits	52	Shared Neighborhood Hits	49
SwissProt Accessions	Q8NEJ0	Gene names	DUSP18, LMWDSP20
Domain Architecture
Description	Dual specificity protein phosphatase 18 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular weight dual specificity phosphatase 20).

DUS22_MOUSE
θ value	4.74913e-17 (rank : 25)	NC score	0.860252 (rank : 17)
Query Neighborhood Hits	161	Target Neighborhood Hits	57	Shared Neighborhood Hits	56
SwissProt Accessions	Q99N11, Q5SQN9, Q5SQP0	Gene names	Dusp22
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 22 (EC 3.1.3.48) (EC 3.1.3.16) (LMW-DSP2).

SSH1_MOUSE
θ value	4.74913e-17 (rank : 26)	NC score	0.760774 (rank : 39)
Query Neighborhood Hits	161	Target Neighborhood Hits	107	Shared Neighborhood Hits	54
SwissProt Accessions	Q76I79, Q3TDG3, Q69ZM4, Q811E5	Gene names	Ssh1, Kiaa1298, Ssh1l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (mSSH-1L).

DUS14_HUMAN
θ value	1.38178e-16 (rank : 27)	NC score	0.851654 (rank : 23)
Query Neighborhood Hits	161	Target Neighborhood Hits	64	Shared Neighborhood Hits	52
SwissProt Accessions	O95147	Gene names	DUSP14, MKP6
Domain Architecture
Description	Dual specificity protein phosphatase 14 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 6) (MAP kinase phosphatase 6) (MKP-6) (MKP-1-like protein tyrosine phosphatase) (MKP- L).

DUS18_MOUSE
θ value	1.80466e-16 (rank : 28)	NC score	0.832866 (rank : 28)
Query Neighborhood Hits	161	Target Neighborhood Hits	53	Shared Neighborhood Hits	49
SwissProt Accessions	Q8VE01	Gene names	Dusp18
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 18 (EC 3.1.3.48) (EC 3.1.3.16).

SSH3_HUMAN
θ value	3.07829e-16 (rank : 29)	NC score	0.773593 (rank : 34)
Query Neighborhood Hits	161	Target Neighborhood Hits	75	Shared Neighborhood Hits	52
SwissProt Accessions	Q8TE77, Q6PK42, Q76I75, Q8N9L8, Q8WYL0, Q9NV45, Q9NWZ7	Gene names	SSH3, SSH3L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 3 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-3L) (hSSH-3L).

DUS14_MOUSE
θ value	5.25075e-16 (rank : 30)	NC score	0.852894 (rank : 22)
Query Neighborhood Hits	161	Target Neighborhood Hits	67	Shared Neighborhood Hits	54
SwissProt Accessions	Q9JLY7, Q9D715	Gene names	Dusp14, Mkp6
Domain Architecture
Description	Dual specificity protein phosphatase 14 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 6) (MAP kinase phosphatase 6) (MKP-6).

DUS19_HUMAN
θ value	2.60593e-15 (rank : 31)	NC score	0.856101 (rank : 19)
Query Neighborhood Hits	161	Target Neighborhood Hits	52	Shared Neighborhood Hits	50
SwissProt Accessions	Q8WTR2, Q8WYN4	Gene names	DUSP19, DUSP17, SKRP1
Domain Architecture
Description	Dual specificity protein phosphatase 19 (EC 3.1.3.48) (EC 3.1.3.16) (Stress-activated protein kinase pathway-regulating phosphatase 1) (Protein phosphatase SKRP1).

DUS21_HUMAN
θ value	5.8054e-15 (rank : 32)	NC score	0.833266 (rank : 26)
Query Neighborhood Hits	161	Target Neighborhood Hits	52	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H596, Q6IAJ6, Q6YDQ8	Gene names	DUSP21, LMWDSP21
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 21 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular weight dual specificity phosphatase 21).

DUS19_MOUSE
θ value	7.58209e-15 (rank : 33)	NC score	0.850370 (rank : 24)
Query Neighborhood Hits	161	Target Neighborhood Hits	58	Shared Neighborhood Hits	50
SwissProt Accessions	Q8K4T5	Gene names	Dusp19, Skrp1
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 19 (EC 3.1.3.48) (EC 3.1.3.16) (Stress-activated protein kinase pathway-regulating phosphatase 1) (Protein phosphatase SKRP1).

DUS15_HUMAN
θ value	2.20605e-14 (rank : 34)	NC score	0.840928 (rank : 25)
Query Neighborhood Hits	161	Target Neighborhood Hits	60	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H1R2, Q5QP62, Q5QP63, Q5QP65, Q6PGN7, Q8N826, Q9BX24	Gene names	DUSP15, C20orf57, VHY
Domain Architecture
Description	Dual specificity protein phosphatase 15 (EC 3.1.3.48) (EC 3.1.3.16) (Vaccinia virus VH1-related dual-specific protein phosphatase Y) (VH1- related member Y).

DUS12_MOUSE
θ value	1.33837e-11 (rank : 35)	NC score	0.778055 (rank : 31)
Query Neighborhood Hits	161	Target Neighborhood Hits	60	Shared Neighborhood Hits	50
SwissProt Accessions	Q9D0T2, Q9EQD3	Gene names	Dusp12
Domain Architecture
Description	Dual specificity protein phosphatase 12 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity phosphatase T-DSP4) (Dual specificity phosphatase VH1).

DUS3_HUMAN
θ value	1.47974e-10 (rank : 36)	NC score	0.819882 (rank : 29)
Query Neighborhood Hits	161	Target Neighborhood Hits	58	Shared Neighborhood Hits	50
SwissProt Accessions	P51452	Gene names	DUSP3, VHR
Domain Architecture
Description	Dual specificity protein phosphatase 3 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase VHR).

DUS3_MOUSE
θ value	3.29651e-10 (rank : 37)	NC score	0.818715 (rank : 30)
Query Neighborhood Hits	161	Target Neighborhood Hits	54	Shared Neighborhood Hits	51
SwissProt Accessions	Q9D7X3	Gene names	Dusp3
Domain Architecture
Description	Dual specificity protein phosphatase 3 (EC 3.1.3.48) (EC 3.1.3.16) (T- DSP11).

DUS12_HUMAN
θ value	5.62301e-10 (rank : 38)	NC score	0.761632 (rank : 38)
Query Neighborhood Hits	161	Target Neighborhood Hits	60	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UNI6	Gene names	DUSP12
Domain Architecture
Description	Dual specificity protein phosphatase 12 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity tyrosine phosphatase YVH1).

DUS13_MOUSE
θ value	8.11959e-09 (rank : 39)	NC score	0.776170 (rank : 33)
Query Neighborhood Hits	161	Target Neighborhood Hits	56	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QYJ7	Gene names	Dusp13, Tmdp
Domain Architecture
Description	Dual specificity protein phosphatase 13 (EC 3.1.3.48) (EC 3.1.3.16) (Testis- and skeletal muscle-specific DSP) (Dual specificity tyrosine phosphatase TS-DSP6).

DUS13_HUMAN
θ value	1.17247e-07 (rank : 40)	NC score	0.771137 (rank : 35)
Query Neighborhood Hits	161	Target Neighborhood Hits	59	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UII6, Q5JSC6, Q96GC2	Gene names	DUSP13, TMDP
Domain Architecture
Description	Dual specificity protein phosphatase 13 (EC 3.1.3.48) (EC 3.1.3.16) (Testis- and skeletal-muscle-specific DSP) (Dual specificity phosphatase SKRP4).

OGFR_HUMAN
θ value	2.88788e-06 (rank : 41)	NC score	0.071056 (rank : 60)
Query Neighborhood Hits	161	Target Neighborhood Hits	1582	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

STYL1_HUMAN
θ value	8.40245e-06 (rank : 42)	NC score	0.767042 (rank : 36)
Query Neighborhood Hits	161	Target Neighborhood Hits	43	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y6J8, Q9UBP1, Q9UK06, Q9UK07, Q9UKG2, Q9UKG3	Gene names	STYXL1, DUSP24, MKSTYX
Domain Architecture
Description	Serine/threonine/tyrosine-interacting-like protein 1 (Dual specificity protein phosphatase 24) (Map kinase phosphatase-like protein MK-STYX) (Dual specificity phosphatase inhibitor MK-STYX).

DUS23_HUMAN
θ value	0.00035302 (rank : 43)	NC score	0.337620 (rank : 44)
Query Neighborhood Hits	161	Target Neighborhood Hits	98	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BVJ7, Q9NX48	Gene names	DUSP23, LDP3, VHZ
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3) (VH1-like phosphatase Z).

MUC1_HUMAN
θ value	0.000461057 (rank : 44)	NC score	0.042343 (rank : 69)
Query Neighborhood Hits	161	Target Neighborhood Hits	975	Shared Neighborhood Hits	48
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

DUS23_MOUSE
θ value	0.00134147 (rank : 45)	NC score	0.311448 (rank : 46)
Query Neighborhood Hits	161	Target Neighborhood Hits	94	Shared Neighborhood Hits	45
SwissProt Accessions	Q6NT99, Q9CW48	Gene names	Dusp23, Ldp3
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3).

PTPM1_MOUSE
θ value	0.00175202 (rank : 46)	NC score	0.513350 (rank : 42)
Query Neighborhood Hits	161	Target Neighborhood Hits	64	Shared Neighborhood Hits	56
SwissProt Accessions	Q66GT5, Q9CSJ8, Q9D622	Gene names	Ptpmt1, Plip
Domain Architecture	No domain graphic available
Description	Protein-tyrosine phosphatase mitochondrial 1, mitochondrial precursor (EC 3.1.3.48) (EC 3.1.3.16) (PTEN-like phosphatase) (Phosphoinositide lipid phosphatase).

CT174_HUMAN
θ value	0.00228821 (rank : 47)	NC score	0.076630 (rank : 59)
Query Neighborhood Hits	161	Target Neighborhood Hits	181	Shared Neighborhood Hits	18
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

K1802_MOUSE
θ value	0.00228821 (rank : 48)	NC score	0.036550 (rank : 72)
Query Neighborhood Hits	161	Target Neighborhood Hits	1596	Shared Neighborhood Hits	57
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

CC14B_HUMAN
θ value	0.00390308 (rank : 49)	NC score	0.317792 (rank : 45)
Query Neighborhood Hits	161	Target Neighborhood Hits	114	Shared Neighborhood Hits	57
SwissProt Accessions	O60729, O43183, O60730	Gene names	CDC14B
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

PTPM1_HUMAN
θ value	0.00390308 (rank : 50)	NC score	0.477142 (rank : 43)
Query Neighborhood Hits	161	Target Neighborhood Hits	60	Shared Neighborhood Hits	53
SwissProt Accessions	Q8WUK0, Q7Z557, Q96CR2, Q9BXV8	Gene names	PTPMT1, MOSP, PLIP
Domain Architecture	No domain graphic available
Description	Protein-tyrosine phosphatase mitochondrial 1, mitochondrial precursor (EC 3.1.3.48) (EC 3.1.3.16) (PTEN-like phosphatase) (Phosphoinositide lipid phosphatase).

PRRT3_HUMAN
θ value	0.00509761 (rank : 51)	NC score	0.048432 (rank : 67)
Query Neighborhood Hits	161	Target Neighborhood Hits	998	Shared Neighborhood Hits	52
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

PKHG4_HUMAN
θ value	0.00869519 (rank : 52)	NC score	0.040348 (rank : 70)
Query Neighborhood Hits	161	Target Neighborhood Hits	200	Shared Neighborhood Hits	11
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

ULK1_MOUSE
θ value	0.0148317 (rank : 53)	NC score	0.005703 (rank : 146)
Query Neighborhood Hits	161	Target Neighborhood Hits	1214	Shared Neighborhood Hits	33
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

SNPC4_HUMAN
θ value	0.0252991 (rank : 54)	NC score	0.049029 (rank : 66)
Query Neighborhood Hits	161	Target Neighborhood Hits	589	Shared Neighborhood Hits	34
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

CG1_HUMAN
θ value	0.0330416 (rank : 55)	NC score	0.051765 (rank : 65)
Query Neighborhood Hits	161	Target Neighborhood Hits	222	Shared Neighborhood Hits	14
SwissProt Accessions	Q13495	Gene names	CXorf6, CG1
Domain Architecture	No domain graphic available
Description	CG1 protein (F18).

CC14B_MOUSE
θ value	0.0563607 (rank : 56)	NC score	0.280109 (rank : 49)
Query Neighborhood Hits	161	Target Neighborhood Hits	103	Shared Neighborhood Hits	51
SwissProt Accessions	Q6PFY9, Q80WC4, Q8BLV5	Gene names	Cdc14b
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

DTNB_MOUSE
θ value	0.0563607 (rank : 57)	NC score	0.021368 (rank : 100)
Query Neighborhood Hits	161	Target Neighborhood Hits	263	Shared Neighborhood Hits	3
SwissProt Accessions	O70585, O70563, Q9CTZ1	Gene names	Dtnb
Domain Architecture
Description	Dystrobrevin beta (Beta-dystrobrevin) (DTN-B) (MDTN-B).

MILK2_HUMAN
θ value	0.0563607 (rank : 58)	NC score	0.033408 (rank : 74)
Query Neighborhood Hits	161	Target Neighborhood Hits	457	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

MK15_HUMAN
θ value	0.0563607 (rank : 59)	NC score	0.005731 (rank : 145)
Query Neighborhood Hits	161	Target Neighborhood Hits	1038	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

TP4A2_HUMAN
θ value	0.0961366 (rank : 60)	NC score	0.129509 (rank : 56)
Query Neighborhood Hits	161	Target Neighborhood Hits	56	Shared Neighborhood Hits	28
SwissProt Accessions	Q12974, O00649, Q15197, Q15259, Q15260, Q15261	Gene names	PTP4A2, PRL2, PTPCAAX2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2) (PTP(CAAXII)) (HU-PP-1) (OV-1).

TP4A2_MOUSE
θ value	0.0961366 (rank : 61)	NC score	0.129509 (rank : 57)
Query Neighborhood Hits	161	Target Neighborhood Hits	56	Shared Neighborhood Hits	28
SwissProt Accessions	O70274, Q3U1K7	Gene names	Ptp4a2, Prl2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2).

BSN_MOUSE
θ value	0.125558 (rank : 62)	NC score	0.044920 (rank : 68)
Query Neighborhood Hits	161	Target Neighborhood Hits	2057	Shared Neighborhood Hits	75
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

MEF2B_MOUSE
θ value	0.125558 (rank : 63)	NC score	0.028730 (rank : 83)
Query Neighborhood Hits	161	Target Neighborhood Hits	218	Shared Neighborhood Hits	19
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

EPM2A_HUMAN
θ value	0.163984 (rank : 64)	NC score	0.280196 (rank : 48)
Query Neighborhood Hits	161	Target Neighborhood Hits	47	Shared Neighborhood Hits	38
SwissProt Accessions	O95278, O95483, Q8IU96, Q8IX24, Q8IX25, Q9BS66, Q9UEN2	Gene names	EPM2A
Domain Architecture	No domain graphic available
Description	Laforin (EC 3.1.3.48) (EC 3.1.3.16) (Lafora PTPase) (LAFPTPase).

OBSCN_HUMAN
θ value	0.163984 (rank : 65)	NC score	0.007988 (rank : 138)
Query Neighborhood Hits	161	Target Neighborhood Hits	1931	Shared Neighborhood Hits	50
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

TARA_HUMAN
θ value	0.163984 (rank : 66)	NC score	0.021314 (rank : 101)
Query Neighborhood Hits	161	Target Neighborhood Hits	1626	Shared Neighborhood Hits	46
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

ZN750_MOUSE
θ value	0.163984 (rank : 67)	NC score	0.037614 (rank : 71)
Query Neighborhood Hits	161	Target Neighborhood Hits	346	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

CO5A2_HUMAN
θ value	0.21417 (rank : 68)	NC score	0.027618 (rank : 90)
Query Neighborhood Hits	161	Target Neighborhood Hits	760	Shared Neighborhood Hits	43
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

EPM2A_MOUSE
θ value	0.21417 (rank : 69)	NC score	0.281063 (rank : 47)
Query Neighborhood Hits	161	Target Neighborhood Hits	47	Shared Neighborhood Hits	37
SwissProt Accessions	Q9WUA5, Q8BY80	Gene names	Epm2a
Domain Architecture	No domain graphic available
Description	Laforin (EC 3.1.3.48) (EC 3.1.3.16) (Lafora PTPase) (LAFPTPase).

JPH2_HUMAN
θ value	0.21417 (rank : 70)	NC score	0.031954 (rank : 77)
Query Neighborhood Hits	161	Target Neighborhood Hits	639	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

PHLB1_MOUSE
θ value	0.21417 (rank : 71)	NC score	0.018336 (rank : 108)
Query Neighborhood Hits	161	Target Neighborhood Hits	678	Shared Neighborhood Hits	23
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

TP4A1_HUMAN
θ value	0.21417 (rank : 72)	NC score	0.130843 (rank : 54)
Query Neighborhood Hits	161	Target Neighborhood Hits	68	Shared Neighborhood Hits	33
SwissProt Accessions	Q93096, O00648, Q49A54	Gene names	PTP4A1, PRL1, PTPCAAX1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1) (PTP(CAAXI)).

TP4A1_MOUSE
θ value	0.21417 (rank : 73)	NC score	0.130843 (rank : 55)
Query Neighborhood Hits	161	Target Neighborhood Hits	68	Shared Neighborhood Hits	33
SwissProt Accessions	Q63739, O09097, O09154, Q3UFU9	Gene names	Ptp4a1, Prl1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1).

BIN1_HUMAN
θ value	0.279714 (rank : 74)	NC score	0.027444 (rank : 91)
Query Neighborhood Hits	161	Target Neighborhood Hits	335	Shared Neighborhood Hits	19
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

SAPS1_HUMAN
θ value	0.279714 (rank : 75)	NC score	0.028718 (rank : 84)
Query Neighborhood Hits	161	Target Neighborhood Hits	704	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

CAC1G_HUMAN
θ value	0.365318 (rank : 76)	NC score	0.012961 (rank : 122)
Query Neighborhood Hits	161	Target Neighborhood Hits	587	Shared Neighborhood Hits	26
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

DUS11_MOUSE
θ value	0.365318 (rank : 77)	NC score	0.105361 (rank : 58)
Query Neighborhood Hits	161	Target Neighborhood Hits	41	Shared Neighborhood Hits	22
SwissProt Accessions	Q6NXK5, Q8BTR4, Q8BYE4	Gene names	Dusp11, Pir1
Domain Architecture	No domain graphic available
Description	RNA/RNP complex-1-interacting phosphatase (EC 3.1.3.-) (Phosphatase that interacts with RNA/RNP complex 1) (Dual specificity protein phosphatase 11).

IASPP_MOUSE
θ value	0.365318 (rank : 78)	NC score	0.029219 (rank : 81)
Query Neighborhood Hits	161	Target Neighborhood Hits	1024	Shared Neighborhood Hits	47
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

NUP53_MOUSE
θ value	0.365318 (rank : 79)	NC score	0.033449 (rank : 73)
Query Neighborhood Hits	161	Target Neighborhood Hits	94	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R4R6, Q9D7J2	Gene names	Nup35, Mp44, Nup53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

TP4A3_HUMAN
θ value	0.365318 (rank : 80)	NC score	0.157625 (rank : 52)
Query Neighborhood Hits	161	Target Neighborhood Hits	62	Shared Neighborhood Hits	37
SwissProt Accessions	O75365, Q8IVN5, Q99849, Q9BTW5	Gene names	PTP4A3, PRL3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3) (PRL-R).

TP4A3_MOUSE
θ value	0.365318 (rank : 81)	NC score	0.153764 (rank : 53)
Query Neighborhood Hits	161	Target Neighborhood Hits	60	Shared Neighborhood Hits	37
SwissProt Accessions	Q9D658, O70275, Q3T9Z5, Q9CTC8	Gene names	Ptp4a3, Prl3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3).

IL3B2_MOUSE
θ value	0.47712 (rank : 82)	NC score	0.029872 (rank : 79)
Query Neighborhood Hits	161	Target Neighborhood Hits	372	Shared Neighborhood Hits	21
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

SPEG_MOUSE
θ value	0.47712 (rank : 83)	NC score	0.009113 (rank : 133)
Query Neighborhood Hits	161	Target Neighborhood Hits	1959	Shared Neighborhood Hits	60
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

CC14A_HUMAN
θ value	0.62314 (rank : 84)	NC score	0.255633 (rank : 51)
Query Neighborhood Hits	161	Target Neighborhood Hits	133	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UNH5, O43171, O60727, O60728, Q8IXX0	Gene names	CDC14A
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

CC14A_MOUSE
θ value	0.62314 (rank : 85)	NC score	0.258645 (rank : 50)
Query Neighborhood Hits	161	Target Neighborhood Hits	117	Shared Neighborhood Hits	53
SwissProt Accessions	Q6GQT0, Q8BZ66	Gene names	Cdc14a
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

EHMT2_MOUSE
θ value	0.62314 (rank : 86)	NC score	0.008603 (rank : 135)
Query Neighborhood Hits	161	Target Neighborhood Hits	750	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

IL3RB_MOUSE
θ value	0.62314 (rank : 87)	NC score	0.029805 (rank : 80)
Query Neighborhood Hits	161	Target Neighborhood Hits	355	Shared Neighborhood Hits	23
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

MLL3_HUMAN
θ value	0.62314 (rank : 88)	NC score	0.018894 (rank : 105)
Query Neighborhood Hits	161	Target Neighborhood Hits	1644	Shared Neighborhood Hits	46
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

NFH_MOUSE
θ value	0.62314 (rank : 89)	NC score	0.017965 (rank : 109)
Query Neighborhood Hits	161	Target Neighborhood Hits	2247	Shared Neighborhood Hits	64
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

EFS_MOUSE
θ value	0.813845 (rank : 90)	NC score	0.028315 (rank : 87)
Query Neighborhood Hits	161	Target Neighborhood Hits	389	Shared Neighborhood Hits	27
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

SSBP4_HUMAN
θ value	0.813845 (rank : 91)	NC score	0.023406 (rank : 98)
Query Neighborhood Hits	161	Target Neighborhood Hits	753	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

WDFY3_HUMAN
θ value	0.813845 (rank : 92)	NC score	0.011107 (rank : 127)
Query Neighborhood Hits	161	Target Neighborhood Hits	348	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IZQ1, Q4W5K5, Q6P0Q5, Q8N1T2, Q96BS7, Q96N85, Q9Y2J7	Gene names	WDFY3, KIAA0993
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy).

ZN395_HUMAN
θ value	0.813845 (rank : 93)	NC score	0.032702 (rank : 76)
Query Neighborhood Hits	161	Target Neighborhood Hits	64	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H8N7, Q6F6H2, Q9BY72, Q9NPB2, Q9NS57, Q9NS58, Q9NS59	Gene names	ZNF395, HDBP2, PBF
Domain Architecture	No domain graphic available
Description	Zinc finger protein 395 (Papillomavirus-binding factor) (Papillomavirus regulatory factor 1) (PRF-1) (Huntington disease gene regulatory region-binding protein 2) (HDBP-2) (HD gene regulatory region-binding protein 2) (HD-regulating factor 2) (HDRF-2).

PHLPP_HUMAN
θ value	1.06291 (rank : 94)	NC score	0.018373 (rank : 107)
Query Neighborhood Hits	161	Target Neighborhood Hits	604	Shared Neighborhood Hits	35
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

PKD1_HUMAN
θ value	1.06291 (rank : 95)	NC score	0.011406 (rank : 126)
Query Neighborhood Hits	161	Target Neighborhood Hits	387	Shared Neighborhood Hits	4
SwissProt Accessions	P98161, Q15140, Q15141	Gene names	PKD1
Domain Architecture
Description	Polycystin-1 precursor (Autosomal dominant polycystic kidney disease protein 1).

SC6A5_MOUSE
θ value	1.06291 (rank : 96)	NC score	0.007105 (rank : 141)
Query Neighborhood Hits	161	Target Neighborhood Hits	135	Shared Neighborhood Hits	7
SwissProt Accessions	Q761V0, Q8CFM5, Q91ZQ2	Gene names	Slc6a5, Glyt2
Domain Architecture	No domain graphic available
Description	Sodium- and chloride-dependent glycine transporter 2 (GlyT2) (GlyT-2) (Solute carrier family 6 member 5).

SP5_HUMAN
θ value	1.06291 (rank : 97)	NC score	0.000089 (rank : 162)
Query Neighborhood Hits	161	Target Neighborhood Hits	832	Shared Neighborhood Hits	18
SwissProt Accessions	Q6BEB4	Gene names	SP5
Domain Architecture	No domain graphic available
Description	Transcription factor Sp5.

SP5_MOUSE
θ value	1.06291 (rank : 98)	NC score	0.000074 (rank : 163)
Query Neighborhood Hits	161	Target Neighborhood Hits	821	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JHX2	Gene names	Sp5
Domain Architecture
Description	Transcription factor Sp5.

T22D4_HUMAN
θ value	1.06291 (rank : 99)	NC score	0.028671 (rank : 85)
Query Neighborhood Hits	161	Target Neighborhood Hits	403	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

ICAM4_HUMAN
θ value	1.38821 (rank : 100)	NC score	0.027920 (rank : 89)
Query Neighborhood Hits	161	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q14773, Q14771, Q14772, Q16375	Gene names	ICAM4, LW
Domain Architecture
Description	Intercellular adhesion molecule 4 precursor (ICAM-4) (Landsteiner- Wiener blood group glycoprotein) (LW blood group protein) (CD242 antigen).

PAK4_MOUSE
θ value	1.38821 (rank : 101)	NC score	0.002702 (rank : 156)
Query Neighborhood Hits	161	Target Neighborhood Hits	1098	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

RGS3_HUMAN
θ value	1.38821 (rank : 102)	NC score	0.016133 (rank : 115)
Query Neighborhood Hits	161	Target Neighborhood Hits	1375	Shared Neighborhood Hits	52
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

TEX14_MOUSE
θ value	1.38821 (rank : 103)	NC score	0.003559 (rank : 153)
Query Neighborhood Hits	161	Target Neighborhood Hits	1333	Shared Neighborhood Hits	18
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

CASC3_MOUSE
θ value	1.81305 (rank : 104)	NC score	0.026495 (rank : 94)
Query Neighborhood Hits	161	Target Neighborhood Hits	333	Shared Neighborhood Hits	21
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

CEL_HUMAN
θ value	1.81305 (rank : 105)	NC score	0.014482 (rank : 119)
Query Neighborhood Hits	161	Target Neighborhood Hits	896	Shared Neighborhood Hits	35
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CO4A1_HUMAN
θ value	1.81305 (rank : 106)	NC score	0.017186 (rank : 112)
Query Neighborhood Hits	161	Target Neighborhood Hits	425	Shared Neighborhood Hits	34
SwissProt Accessions	P02462	Gene names	COL4A1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

COBA2_MOUSE
θ value	1.81305 (rank : 107)	NC score	0.018444 (rank : 106)
Query Neighborhood Hits	161	Target Neighborhood Hits	501	Shared Neighborhood Hits	35
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

NU133_HUMAN
θ value	1.81305 (rank : 108)	NC score	0.017945 (rank : 110)
Query Neighborhood Hits	161	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WUM0, Q9H9W2, Q9NV71, Q9NVC4	Gene names	NUP133
Domain Architecture
Description	Nuclear pore complex protein Nup133 (Nucleoporin Nup133) (133 kDa nucleoporin).

PER3_HUMAN
θ value	1.81305 (rank : 109)	NC score	0.016909 (rank : 114)
Query Neighborhood Hits	161	Target Neighborhood Hits	479	Shared Neighborhood Hits	31
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

5HT7R_HUMAN
θ value	2.36792 (rank : 110)	NC score	-0.003517 (rank : 165)
Query Neighborhood Hits	161	Target Neighborhood Hits	848	Shared Neighborhood Hits	2
SwissProt Accessions	P34969, P78336, P78372, P78516	Gene names	HTR7
Domain Architecture
Description	5-hydroxytryptamine 7 receptor (5-HT-7) (Serotonin receptor 7) (5-HT- X) (5HT7).

DNMT1_MOUSE
θ value	2.36792 (rank : 111)	NC score	0.019268 (rank : 104)
Query Neighborhood Hits	161	Target Neighborhood Hits	137	Shared Neighborhood Hits	4
SwissProt Accessions	P13864, P97413, Q80ZU3, Q9CSC6, Q9QXX6	Gene names	Dnmt1, Dnmt, Met1, Uim
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase MmuI) (DNA MTase MmuI) (MCMT) (M.MmuI) (Met-1).

ITAM_HUMAN
θ value	2.36792 (rank : 112)	NC score	0.007421 (rank : 140)
Query Neighborhood Hits	161	Target Neighborhood Hits	78	Shared Neighborhood Hits	3
SwissProt Accessions	P11215	Gene names	ITGAM, CD11B, CR3A
Domain Architecture
Description	Integrin alpha-M precursor (Cell surface glycoprotein MAC-1 alpha subunit) (CR-3 alpha chain) (Leukocyte adhesion receptor MO1) (Neutrophil adherence receptor) (CD11b antigen).

MILK1_HUMAN
θ value	2.36792 (rank : 113)	NC score	0.033123 (rank : 75)
Query Neighborhood Hits	161	Target Neighborhood Hits	427	Shared Neighborhood Hits	38
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

ZEP1_MOUSE
θ value	2.36792 (rank : 114)	NC score	0.005657 (rank : 147)
Query Neighborhood Hits	161	Target Neighborhood Hits	1063	Shared Neighborhood Hits	27
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

ZIMP7_MOUSE
θ value	2.36792 (rank : 115)	NC score	0.017185 (rank : 113)
Query Neighborhood Hits	161	Target Neighborhood Hits	566	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

CSKI1_HUMAN
θ value	3.0926 (rank : 116)	NC score	0.020456 (rank : 102)
Query Neighborhood Hits	161	Target Neighborhood Hits	997	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

RHBD1_HUMAN
θ value	3.0926 (rank : 117)	NC score	0.010748 (rank : 128)
Query Neighborhood Hits	161	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	O75783, Q9NQ85	Gene names	RHBDL1, RHBDL
Domain Architecture
Description	Rhomboid-related protein 1 (EC 3.4.21.105) (RRP) (Rhomboid-like protein 1).

ROBO3_MOUSE
θ value	3.0926 (rank : 118)	NC score	0.004308 (rank : 151)
Query Neighborhood Hits	161	Target Neighborhood Hits	524	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

ULK1_HUMAN
θ value	3.0926 (rank : 119)	NC score	0.004901 (rank : 148)
Query Neighborhood Hits	161	Target Neighborhood Hits	1121	Shared Neighborhood Hits	34
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

CABIN_HUMAN
θ value	4.03905 (rank : 120)	NC score	0.026756 (rank : 93)
Query Neighborhood Hits	161	Target Neighborhood Hits	490	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CO5A3_HUMAN
θ value	4.03905 (rank : 121)	NC score	0.014667 (rank : 118)
Query Neighborhood Hits	161	Target Neighborhood Hits	433	Shared Neighborhood Hits	31
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

K0310_HUMAN
θ value	4.03905 (rank : 122)	NC score	0.029060 (rank : 82)
Query Neighborhood Hits	161	Target Neighborhood Hits	420	Shared Neighborhood Hits	28
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

LAG3_MOUSE
θ value	4.03905 (rank : 123)	NC score	0.012704 (rank : 123)
Query Neighborhood Hits	161	Target Neighborhood Hits	117	Shared Neighborhood Hits	4
SwissProt Accessions	Q61790, Q0VBL2	Gene names	Lag3
Domain Architecture
Description	Lymphocyte activation gene 3 protein precursor (LAG-3) (CD223 antigen).

MEFV_HUMAN
θ value	4.03905 (rank : 124)	NC score	0.001860 (rank : 159)
Query Neighborhood Hits	161	Target Neighborhood Hits	431	Shared Neighborhood Hits	10
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

PSL1_HUMAN
θ value	4.03905 (rank : 125)	NC score	0.015571 (rank : 117)
Query Neighborhood Hits	161	Target Neighborhood Hits	650	Shared Neighborhood Hits	25
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

BAT2_MOUSE
θ value	5.27518 (rank : 126)	NC score	0.028291 (rank : 88)
Query Neighborhood Hits	161	Target Neighborhood Hits	947	Shared Neighborhood Hits	55
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

K2027_MOUSE
θ value	5.27518 (rank : 127)	NC score	0.011837 (rank : 125)
Query Neighborhood Hits	161	Target Neighborhood Hits	106	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BWS5, Q69Z30	Gene names	Kiaa2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

MAST1_HUMAN
θ value	5.27518 (rank : 128)	NC score	0.003287 (rank : 154)
Query Neighborhood Hits	161	Target Neighborhood Hits	1146	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MAST1_MOUSE
θ value	5.27518 (rank : 129)	NC score	0.003198 (rank : 155)
Query Neighborhood Hits	161	Target Neighborhood Hits	1123	Shared Neighborhood Hits	30
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

PTPRE_HUMAN
θ value	5.27518 (rank : 130)	NC score	0.017787 (rank : 111)
Query Neighborhood Hits	161	Target Neighborhood Hits	92	Shared Neighborhood Hits	24
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

SYIM_HUMAN
θ value	5.27518 (rank : 131)	NC score	0.007648 (rank : 139)
Query Neighborhood Hits	161	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NSE4, Q6PI85, Q7L439, Q86WU9, Q96D91	Gene names	IARS2
Domain Architecture	No domain graphic available
Description	Isoleucyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.5) (Isoleucine--tRNA ligase) (IleRS).

T22D4_MOUSE
θ value	5.27518 (rank : 132)	NC score	0.026960 (rank : 92)
Query Neighborhood Hits	161	Target Neighborhood Hits	92	Shared Neighborhood Hits	16
SwissProt Accessions	Q9EQN3	Gene names	Tsc22d4, Tilz2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2).

TCOF_HUMAN
θ value	5.27518 (rank : 133)	NC score	0.028649 (rank : 86)
Query Neighborhood Hits	161	Target Neighborhood Hits	543	Shared Neighborhood Hits	25
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

BCL9_HUMAN
θ value	6.88961 (rank : 134)	NC score	0.026211 (rank : 95)
Query Neighborhood Hits	161	Target Neighborhood Hits	1008	Shared Neighborhood Hits	52
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

BCL9_MOUSE
θ value	6.88961 (rank : 135)	NC score	0.030900 (rank : 78)
Query Neighborhood Hits	161	Target Neighborhood Hits	770	Shared Neighborhood Hits	51
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

BRD8_MOUSE
θ value	6.88961 (rank : 136)	NC score	0.010176 (rank : 130)
Query Neighborhood Hits	161	Target Neighborhood Hits	422	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

DCX_MOUSE
θ value	6.88961 (rank : 137)	NC score	0.006965 (rank : 142)
Query Neighborhood Hits	161	Target Neighborhood Hits	124	Shared Neighborhood Hits	9
SwissProt Accessions	O88809	Gene names	Dcx, Dcn
Domain Architecture
Description	Neuronal migration protein doublecortin (Lissencephalin-X) (Lis-X) (Doublin).

FGD1_MOUSE
θ value	6.88961 (rank : 138)	NC score	0.010479 (rank : 129)
Query Neighborhood Hits	161	Target Neighborhood Hits	387	Shared Neighborhood Hits	27
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FOXC2_HUMAN
θ value	6.88961 (rank : 139)	NC score	0.001280 (rank : 160)
Query Neighborhood Hits	161	Target Neighborhood Hits	236	Shared Neighborhood Hits	11
SwissProt Accessions	Q99958	Gene names	FOXC2, FKHL14, MFH1
Domain Architecture
Description	Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14).

GA2L2_MOUSE
θ value	6.88961 (rank : 140)	NC score	0.011943 (rank : 124)
Query Neighborhood Hits	161	Target Neighborhood Hits	395	Shared Neighborhood Hits	23
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

NUP53_HUMAN
θ value	6.88961 (rank : 141)	NC score	0.025092 (rank : 96)
Query Neighborhood Hits	161	Target Neighborhood Hits	156	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NFH5, Q4ZFZ9, Q53S95, Q8TDJ1	Gene names	NUP35, MP44, NUP53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

PTPRE_MOUSE
θ value	6.88961 (rank : 142)	NC score	0.014093 (rank : 121)
Query Neighborhood Hits	161	Target Neighborhood Hits	86	Shared Neighborhood Hits	20
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

RPC2_HUMAN
θ value	6.88961 (rank : 143)	NC score	0.009383 (rank : 132)
Query Neighborhood Hits	161	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NW08, Q9NW59	Gene names	POLR3B
Domain Architecture
Description	DNA-directed RNA polymerase III subunit 127.6 kDa polypeptide (EC 2.7.7.6) (RNA polymerase III subunit 2) (RPC2).

RPC2_MOUSE
θ value	6.88961 (rank : 144)	NC score	0.009384 (rank : 131)
Query Neighborhood Hits	161	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	P59470, Q6NVF3	Gene names	Polr3b
Domain Architecture	No domain graphic available
Description	DNA-directed RNA polymerase III subunit 127.6 kDa polypeptide (EC 2.7.7.6) (RNA polymerase III subunit 2) (RPC2).

USBP1_HUMAN
θ value	6.88961 (rank : 145)	NC score	0.008742 (rank : 134)
Query Neighborhood Hits	161	Target Neighborhood Hits	188	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N6Y0, Q8NBX7, Q96KH3, Q9BYI8	Gene names	USHBP1, AIEBP, MCC2
Domain Architecture	No domain graphic available
Description	USH1C-binding protein 1 (Usher syndrome type-1C protein-binding protein 1) (MCC-2) (AIE-75 binding protein).

AATK_HUMAN
θ value	8.99809 (rank : 146)	NC score	0.004290 (rank : 152)
Query Neighborhood Hits	161	Target Neighborhood Hits	1243	Shared Neighborhood Hits	42
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

KCD18_HUMAN
θ value	8.99809 (rank : 147)	NC score	0.006443 (rank : 143)
Query Neighborhood Hits	161	Target Neighborhood Hits	117	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PI47, Q53T21, Q6NW26, Q6PCD8, Q8N9B7, Q96N73	Gene names	KCTD18
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD18.

KLF1_MOUSE
θ value	8.99809 (rank : 148)	NC score	-0.002657 (rank : 164)
Query Neighborhood Hits	161	Target Neighborhood Hits	714	Shared Neighborhood Hits	13
SwissProt Accessions	P46099, O70261	Gene names	Klf1, Elkf
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 1 (Erythroid krueppel-like transcription factor) (EKLF) (Erythroid transcription factor).

MAST2_HUMAN
θ value	8.99809 (rank : 149)	NC score	0.002432 (rank : 157)
Query Neighborhood Hits	161	Target Neighborhood Hits	1189	Shared Neighborhood Hits	35
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MAST2_MOUSE
θ value	8.99809 (rank : 150)	NC score	0.002073 (rank : 158)
Query Neighborhood Hits	161	Target Neighborhood Hits	1110	Shared Neighborhood Hits	28
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MISS_MOUSE
θ value	8.99809 (rank : 151)	NC score	0.019969 (rank : 103)
Query Neighborhood Hits	161	Target Neighborhood Hits	444	Shared Neighborhood Hits	30
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

MUCDL_HUMAN
θ value	8.99809 (rank : 152)	NC score	0.024935 (rank : 97)
Query Neighborhood Hits	161	Target Neighborhood Hits	777	Shared Neighborhood Hits	47
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

MYO9B_HUMAN
θ value	8.99809 (rank : 153)	NC score	0.000840 (rank : 161)
Query Neighborhood Hits	161	Target Neighborhood Hits	641	Shared Neighborhood Hits	19
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

PDZD2_HUMAN
θ value	8.99809 (rank : 154)	NC score	0.008553 (rank : 136)
Query Neighborhood Hits	161	Target Neighborhood Hits	772	Shared Neighborhood Hits	32
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

PTCD1_HUMAN
θ value	8.99809 (rank : 155)	NC score	0.008078 (rank : 137)
Query Neighborhood Hits	161	Target Neighborhood Hits	52	Shared Neighborhood Hits	5
SwissProt Accessions	O75127, Q66K60, Q9UDV2	Gene names	PTCD1, KIAA0632
Domain Architecture	No domain graphic available
Description	Pentatricopeptide repeat protein 1.

PTPRA_MOUSE
θ value	8.99809 (rank : 156)	NC score	0.016067 (rank : 116)
Query Neighborhood Hits	161	Target Neighborhood Hits	93	Shared Neighborhood Hits	21
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRN_HUMAN
θ value	8.99809 (rank : 157)	NC score	0.006115 (rank : 144)
Query Neighborhood Hits	161	Target Neighborhood Hits	156	Shared Neighborhood Hits	18
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

RP1L1_HUMAN
θ value	8.99809 (rank : 158)	NC score	0.023316 (rank : 99)
Query Neighborhood Hits	161	Target Neighborhood Hits	1072	Shared Neighborhood Hits	44
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

RUSC2_MOUSE
θ value	8.99809 (rank : 159)	NC score	0.014437 (rank : 120)
Query Neighborhood Hits	161	Target Neighborhood Hits	305	Shared Neighborhood Hits	26
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SMAD6_MOUSE
θ value	8.99809 (rank : 160)	NC score	0.004549 (rank : 150)
Query Neighborhood Hits	161	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	O35182, Q9CW62	Gene names	Smad6, Madh6, Madh7, Msmad6
Domain Architecture
Description	Mothers against decapentaplegic homolog 6 (SMAD 6) (Mothers against DPP homolog 6) (Smad6) (Mad homolog 7).

ZN414_MOUSE
θ value	8.99809 (rank : 161)	NC score	0.004585 (rank : 149)
Query Neighborhood Hits	161	Target Neighborhood Hits	473	Shared Neighborhood Hits	7
SwissProt Accessions	Q9DCK4, Q8CHU9	Gene names	Znf414, Zfp414
Domain Architecture	No domain graphic available
Description	Zinc finger protein 414.

PRB3_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.057070 (rank : 64)
Query Neighborhood Hits	161	Target Neighborhood Hits	318	Shared Neighborhood Hits	43
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRB4S_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.061931 (rank : 63)
Query Neighborhood Hits	161	Target Neighborhood Hits	330	Shared Neighborhood Hits	45
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PRP1_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.064385 (rank : 61)
Query Neighborhood Hits	161	Target Neighborhood Hits	385	Shared Neighborhood Hits	48
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRP2_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.062964 (rank : 62)
Query Neighborhood Hits	161	Target Neighborhood Hits	347	Shared Neighborhood Hits	45
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

Hits sorted by NC score

DUS8_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	161	Target Neighborhood Hits	161	Shared Neighborhood Hits	161
SwissProt Accessions	Q13202	Gene names	DUSP8, VH5
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH-5).

DUS8_MOUSE
NC score	0.984860 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	161	Target Neighborhood Hits	119	Shared Neighborhood Hits	83
SwissProt Accessions	O09112	Gene names	Dusp8, Nttp1
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Neuronal tyrosine threonine phosphatase 1).

DUS16_HUMAN
NC score	0.970683 (rank : 3)	θ value	1.4755e-135 (rank : 3)
Query Neighborhood Hits	161	Target Neighborhood Hits	112	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BY84, Q9C0G3	Gene names	DUSP16, KIAA1700, MKP7
Domain Architecture
Description	Dual specificity protein phosphatase 16 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 7) (MAP kinase phosphatase 7) (MKP-7).

DUS9_HUMAN
NC score	0.928025 (rank : 4)	θ value	1.28434e-38 (rank : 13)
Query Neighborhood Hits	161	Target Neighborhood Hits	59	Shared Neighborhood Hits	53
SwissProt Accessions	Q99956	Gene names	DUSP9, MKP4
Domain Architecture
Description	Dual specificity protein phosphatase 9 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 4) (MAP kinase phosphatase 4) (MKP-4).

DUS10_MOUSE
NC score	0.926174 (rank : 5)	θ value	2.41655e-45 (rank : 5)
Query Neighborhood Hits	161	Target Neighborhood Hits	62	Shared Neighborhood Hits	53
SwissProt Accessions	Q9ESS0, Q9CZY9	Gene names	Dusp10, Mkp5
Domain Architecture
Description	Dual specificity protein phosphatase 10 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 5) (MAP kinase phosphatase 5) (MKP-5).

DUS10_HUMAN
NC score	0.925276 (rank : 6)	θ value	2.41655e-45 (rank : 4)
Query Neighborhood Hits	161	Target Neighborhood Hits	64	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y6W6	Gene names	DUSP10, MKP5
Domain Architecture
Description	Dual specificity protein phosphatase 10 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 5) (MAP kinase phosphatase 5) (MKP-5).

DUS7_HUMAN
NC score	0.921407 (rank : 7)	θ value	5.57106e-42 (rank : 6)
Query Neighborhood Hits	161	Target Neighborhood Hits	69	Shared Neighborhood Hits	55
SwissProt Accessions	Q16829, Q8NFJ0	Gene names	DUSP7, PYST2
Domain Architecture
Description	Dual specificity protein phosphatase 7 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PYST2).

DUS6_HUMAN
NC score	0.918095 (rank : 8)	θ value	2.34062e-40 (rank : 9)
Query Neighborhood Hits	161	Target Neighborhood Hits	57	Shared Neighborhood Hits	50
SwissProt Accessions	Q16828, O75109, Q53Y75, Q9BSH6	Gene names	DUSP6, MKP3, PYST1
Domain Architecture
Description	Dual specificity protein phosphatase 6 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3) (Dual specificity protein phosphatase PYST1).

DUS2_MOUSE
NC score	0.917996 (rank : 9)	θ value	1.20211e-36 (rank : 15)
Query Neighborhood Hits	161	Target Neighborhood Hits	86	Shared Neighborhood Hits	62
SwissProt Accessions	Q05922, Q60640	Gene names	Dusp2, Pac-1, Pac1
Domain Architecture
Description	Dual specificity protein phosphatase 2 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PAC-1).

DUS6_MOUSE
NC score	0.917697 (rank : 10)	θ value	5.21438e-40 (rank : 10)
Query Neighborhood Hits	161	Target Neighborhood Hits	57	Shared Neighborhood Hits	50
SwissProt Accessions	Q9DBB1, Q542I5, Q9D7L4	Gene names	Dusp6, Mkp3
Domain Architecture
Description	Dual specificity protein phosphatase 6 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3).

DUS2_HUMAN
NC score	0.917600 (rank : 11)	θ value	5.39604e-37 (rank : 14)
Query Neighborhood Hits	161	Target Neighborhood Hits	67	Shared Neighborhood Hits	55
SwissProt Accessions	Q05923	Gene names	DUSP2, PAC1
Domain Architecture
Description	Dual specificity protein phosphatase 2 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PAC-1).

DUS1_MOUSE
NC score	0.911548 (rank : 12)	θ value	1.62093e-41 (rank : 7)
Query Neighborhood Hits	161	Target Neighborhood Hits	72	Shared Neighborhood Hits	57
SwissProt Accessions	P28563	Gene names	Dusp1, 3ch134, Mkp1, Ptpn10, Ptpn16
Domain Architecture
Description	Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase 3CH134) (Protein-tyrosine phosphatase ERP).

DUS1_HUMAN
NC score	0.911100 (rank : 13)	θ value	8.89434e-40 (rank : 11)
Query Neighborhood Hits	161	Target Neighborhood Hits	73	Shared Neighborhood Hits	56
SwissProt Accessions	P28562, Q2V508	Gene names	DUSP1, CL100, MKP1, PTPN10, VH1
Domain Architecture
Description	Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase CL100) (Dual specificity protein phosphatase hVH1).

DUS4_HUMAN
NC score	0.910617 (rank : 14)	θ value	2.76489e-41 (rank : 8)
Query Neighborhood Hits	161	Target Neighborhood Hits	77	Shared Neighborhood Hits	55
SwissProt Accessions	Q13115, Q13524	Gene names	DUSP4, MKP2, VH2
Domain Architecture
Description	Dual specificity protein phosphatase 4 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 2) (MAP kinase phosphatase 2) (MKP-2) (Dual specificity protein phosphatase hVH2).

DUS4_MOUSE
NC score	0.909837 (rank : 15)	θ value	7.52953e-39 (rank : 12)
Query Neighborhood Hits	161	Target Neighborhood Hits	75	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BFV3	Gene names	Dusp4
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 4 (EC 3.1.3.48) (EC 3.1.3.16).

DUS5_HUMAN
NC score	0.907603 (rank : 16)	θ value	3.74554e-30 (rank : 16)
Query Neighborhood Hits	161	Target Neighborhood Hits	82	Shared Neighborhood Hits	57
SwissProt Accessions	Q16690, Q12997	Gene names	DUSP5, VH3
Domain Architecture
Description	Dual specificity protein phosphatase 5 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH3).

DUS22_MOUSE
NC score	0.860252 (rank : 17)	θ value	4.74913e-17 (rank : 25)
Query Neighborhood Hits	161	Target Neighborhood Hits	57	Shared Neighborhood Hits	56
SwissProt Accessions	Q99N11, Q5SQN9, Q5SQP0	Gene names	Dusp22
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 22 (EC 3.1.3.48) (EC 3.1.3.16) (LMW-DSP2).

DUS22_HUMAN
NC score	0.859904 (rank : 18)	θ value	2.7842e-17 (rank : 23)
Query Neighborhood Hits	161	Target Neighborhood Hits	58	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NRW4, Q59GW2, Q5VWR2, Q96AR1	Gene names	DUSP22, JSP1, MKPX
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 22 (EC 3.1.3.48) (EC 3.1.3.16) (JNK-stimulatory phosphatase-1) (JSP-1) (Mitogen-activated protein kinase phosphatase x) (LMW-DSP2).

DUS19_HUMAN
NC score	0.856101 (rank : 19)	θ value	2.60593e-15 (rank : 31)
Query Neighborhood Hits	161	Target Neighborhood Hits	52	Shared Neighborhood Hits	50
SwissProt Accessions	Q8WTR2, Q8WYN4	Gene names	DUSP19, DUSP17, SKRP1
Domain Architecture
Description	Dual specificity protein phosphatase 19 (EC 3.1.3.48) (EC 3.1.3.16) (Stress-activated protein kinase pathway-regulating phosphatase 1) (Protein phosphatase SKRP1).

STYX_HUMAN
NC score	0.855961 (rank : 20)	θ value	4.29542e-18 (rank : 19)
Query Neighborhood Hits	161	Target Neighborhood Hits	60	Shared Neighborhood Hits	57
SwissProt Accessions	Q8WUJ0, Q99850	Gene names	STYX
Domain Architecture
Description	Serine/threonine/tyrosine-interacting protein (Protein tyrosine phosphatase-like protein).

STYX_MOUSE
NC score	0.854776 (rank : 21)	θ value	3.28887e-18 (rank : 18)
Query Neighborhood Hits	161	Target Neighborhood Hits	62	Shared Neighborhood Hits	56
SwissProt Accessions	Q60969, Q3TMA3, Q60970, Q9DCF8	Gene names	Styx
Domain Architecture
Description	Serine/threonine/tyrosine-interacting protein (Protein tyrosine phosphatase-like protein) (Phosphoserine/threonine/tyrosine interaction protein).

DUS14_MOUSE
NC score	0.852894 (rank : 22)	θ value	5.25075e-16 (rank : 30)
Query Neighborhood Hits	161	Target Neighborhood Hits	67	Shared Neighborhood Hits	54
SwissProt Accessions	Q9JLY7, Q9D715	Gene names	Dusp14, Mkp6
Domain Architecture
Description	Dual specificity protein phosphatase 14 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 6) (MAP kinase phosphatase 6) (MKP-6).

DUS14_HUMAN
NC score	0.851654 (rank : 23)	θ value	1.38178e-16 (rank : 27)
Query Neighborhood Hits	161	Target Neighborhood Hits	64	Shared Neighborhood Hits	52
SwissProt Accessions	O95147	Gene names	DUSP14, MKP6
Domain Architecture
Description	Dual specificity protein phosphatase 14 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 6) (MAP kinase phosphatase 6) (MKP-6) (MKP-1-like protein tyrosine phosphatase) (MKP- L).

DUS19_MOUSE
NC score	0.850370 (rank : 24)	θ value	7.58209e-15 (rank : 33)
Query Neighborhood Hits	161	Target Neighborhood Hits	58	Shared Neighborhood Hits	50
SwissProt Accessions	Q8K4T5	Gene names	Dusp19, Skrp1
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 19 (EC 3.1.3.48) (EC 3.1.3.16) (Stress-activated protein kinase pathway-regulating phosphatase 1) (Protein phosphatase SKRP1).

DUS15_HUMAN
NC score	0.840928 (rank : 25)	θ value	2.20605e-14 (rank : 34)
Query Neighborhood Hits	161	Target Neighborhood Hits	60	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H1R2, Q5QP62, Q5QP63, Q5QP65, Q6PGN7, Q8N826, Q9BX24	Gene names	DUSP15, C20orf57, VHY
Domain Architecture
Description	Dual specificity protein phosphatase 15 (EC 3.1.3.48) (EC 3.1.3.16) (Vaccinia virus VH1-related dual-specific protein phosphatase Y) (VH1- related member Y).

DUS21_HUMAN
NC score	0.833266 (rank : 26)	θ value	5.8054e-15 (rank : 32)
Query Neighborhood Hits	161	Target Neighborhood Hits	52	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H596, Q6IAJ6, Q6YDQ8	Gene names	DUSP21, LMWDSP21
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 21 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular weight dual specificity phosphatase 21).

DUS18_HUMAN
NC score	0.832876 (rank : 27)	θ value	4.74913e-17 (rank : 24)
Query Neighborhood Hits	161	Target Neighborhood Hits	52	Shared Neighborhood Hits	49
SwissProt Accessions	Q8NEJ0	Gene names	DUSP18, LMWDSP20
Domain Architecture
Description	Dual specificity protein phosphatase 18 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular weight dual specificity phosphatase 20).

DUS18_MOUSE
NC score	0.832866 (rank : 28)	θ value	1.80466e-16 (rank : 28)
Query Neighborhood Hits	161	Target Neighborhood Hits	53	Shared Neighborhood Hits	49
SwissProt Accessions	Q8VE01	Gene names	Dusp18
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 18 (EC 3.1.3.48) (EC 3.1.3.16).

DUS3_HUMAN
NC score	0.819882 (rank : 29)	θ value	1.47974e-10 (rank : 36)
Query Neighborhood Hits	161	Target Neighborhood Hits	58	Shared Neighborhood Hits	50
SwissProt Accessions	P51452	Gene names	DUSP3, VHR
Domain Architecture
Description	Dual specificity protein phosphatase 3 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase VHR).

DUS3_MOUSE
NC score	0.818715 (rank : 30)	θ value	3.29651e-10 (rank : 37)
Query Neighborhood Hits	161	Target Neighborhood Hits	54	Shared Neighborhood Hits	51
SwissProt Accessions	Q9D7X3	Gene names	Dusp3
Domain Architecture
Description	Dual specificity protein phosphatase 3 (EC 3.1.3.48) (EC 3.1.3.16) (T- DSP11).

DUS12_MOUSE
NC score	0.778055 (rank : 31)	θ value	1.33837e-11 (rank : 35)
Query Neighborhood Hits	161	Target Neighborhood Hits	60	Shared Neighborhood Hits	50
SwissProt Accessions	Q9D0T2, Q9EQD3	Gene names	Dusp12
Domain Architecture
Description	Dual specificity protein phosphatase 12 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity phosphatase T-DSP4) (Dual specificity phosphatase VH1).

SSH3_MOUSE
NC score	0.777559 (rank : 32)	θ value	2.13179e-17 (rank : 22)
Query Neighborhood Hits	161	Target Neighborhood Hits	69	Shared Neighborhood Hits	52
SwissProt Accessions	Q8K330, Q3UDX0	Gene names	Ssh3, Ssh3l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 3 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-3L) (mSSH-3L).

DUS13_MOUSE
NC score	0.776170 (rank : 33)	θ value	8.11959e-09 (rank : 39)
Query Neighborhood Hits	161	Target Neighborhood Hits	56	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QYJ7	Gene names	Dusp13, Tmdp
Domain Architecture
Description	Dual specificity protein phosphatase 13 (EC 3.1.3.48) (EC 3.1.3.16) (Testis- and skeletal muscle-specific DSP) (Dual specificity tyrosine phosphatase TS-DSP6).

SSH3_HUMAN
NC score	0.773593 (rank : 34)	θ value	3.07829e-16 (rank : 29)
Query Neighborhood Hits	161	Target Neighborhood Hits	75	Shared Neighborhood Hits	52
SwissProt Accessions	Q8TE77, Q6PK42, Q76I75, Q8N9L8, Q8WYL0, Q9NV45, Q9NWZ7	Gene names	SSH3, SSH3L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 3 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-3L) (hSSH-3L).

DUS13_HUMAN
NC score	0.771137 (rank : 35)	θ value	1.17247e-07 (rank : 40)
Query Neighborhood Hits	161	Target Neighborhood Hits	59	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UII6, Q5JSC6, Q96GC2	Gene names	DUSP13, TMDP
Domain Architecture
Description	Dual specificity protein phosphatase 13 (EC 3.1.3.48) (EC 3.1.3.16) (Testis- and skeletal-muscle-specific DSP) (Dual specificity phosphatase SKRP4).

STYL1_HUMAN
NC score	0.767042 (rank : 36)	θ value	8.40245e-06 (rank : 42)
Query Neighborhood Hits	161	Target Neighborhood Hits	43	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y6J8, Q9UBP1, Q9UK06, Q9UK07, Q9UKG2, Q9UKG3	Gene names	STYXL1, DUSP24, MKSTYX
Domain Architecture
Description	Serine/threonine/tyrosine-interacting-like protein 1 (Dual specificity protein phosphatase 24) (Map kinase phosphatase-like protein MK-STYX) (Dual specificity phosphatase inhibitor MK-STYX).

SSH1_HUMAN
NC score	0.762828 (rank : 37)	θ value	5.07402e-19 (rank : 17)
Query Neighborhood Hits	161	Target Neighborhood Hits	164	Shared Neighborhood Hits	61
SwissProt Accessions	Q8WYL5, Q6P6C0, Q8N9A7, Q8WYL3, Q8WYL4, Q9P2P8	Gene names	SSH1, KIAA1298, SSH1L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (hSSH-1L).

DUS12_HUMAN
NC score	0.761632 (rank : 38)	θ value	5.62301e-10 (rank : 38)
Query Neighborhood Hits	161	Target Neighborhood Hits	60	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UNI6	Gene names	DUSP12
Domain Architecture
Description	Dual specificity protein phosphatase 12 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity tyrosine phosphatase YVH1).

SSH1_MOUSE
NC score	0.760774 (rank : 39)	θ value	4.74913e-17 (rank : 26)
Query Neighborhood Hits	161	Target Neighborhood Hits	107	Shared Neighborhood Hits	54
SwissProt Accessions	Q76I79, Q3TDG3, Q69ZM4, Q811E5	Gene names	Ssh1, Kiaa1298, Ssh1l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (mSSH-1L).

SSH2_MOUSE
NC score	0.747872 (rank : 40)	θ value	1.24977e-17 (rank : 21)
Query Neighborhood Hits	161	Target Neighborhood Hits	119	Shared Neighborhood Hits	54
SwissProt Accessions	Q5SW75, Q3TDK8, Q3TYP8, Q3U2K3, Q5F268, Q5SW74, Q69ZC3, Q76I78	Gene names	Ssh2, Kiaa1725, Ssh2l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (mSSH-2L).

SSH2_HUMAN
NC score	0.745087 (rank : 41)	θ value	1.24977e-17 (rank : 20)
Query Neighborhood Hits	161	Target Neighborhood Hits	140	Shared Neighborhood Hits	50
SwissProt Accessions	Q76I76, Q8TDB5, Q8WYL1, Q8WYL2, Q96F40, Q96H36, Q9C0D8	Gene names	SSH2, KIAA1725, SSH2L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (hSSH-2L).

PTPM1_MOUSE
NC score	0.513350 (rank : 42)	θ value	0.00175202 (rank : 46)
Query Neighborhood Hits	161	Target Neighborhood Hits	64	Shared Neighborhood Hits	56
SwissProt Accessions	Q66GT5, Q9CSJ8, Q9D622	Gene names	Ptpmt1, Plip
Domain Architecture	No domain graphic available
Description	Protein-tyrosine phosphatase mitochondrial 1, mitochondrial precursor (EC 3.1.3.48) (EC 3.1.3.16) (PTEN-like phosphatase) (Phosphoinositide lipid phosphatase).

PTPM1_HUMAN
NC score	0.477142 (rank : 43)	θ value	0.00390308 (rank : 50)
Query Neighborhood Hits	161	Target Neighborhood Hits	60	Shared Neighborhood Hits	53
SwissProt Accessions	Q8WUK0, Q7Z557, Q96CR2, Q9BXV8	Gene names	PTPMT1, MOSP, PLIP
Domain Architecture	No domain graphic available
Description	Protein-tyrosine phosphatase mitochondrial 1, mitochondrial precursor (EC 3.1.3.48) (EC 3.1.3.16) (PTEN-like phosphatase) (Phosphoinositide lipid phosphatase).

DUS23_HUMAN
NC score	0.337620 (rank : 44)	θ value	0.00035302 (rank : 43)
Query Neighborhood Hits	161	Target Neighborhood Hits	98	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BVJ7, Q9NX48	Gene names	DUSP23, LDP3, VHZ
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3) (VH1-like phosphatase Z).

CC14B_HUMAN
NC score	0.317792 (rank : 45)	θ value	0.00390308 (rank : 49)
Query Neighborhood Hits	161	Target Neighborhood Hits	114	Shared Neighborhood Hits	57
SwissProt Accessions	O60729, O43183, O60730	Gene names	CDC14B
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

DUS23_MOUSE
NC score	0.311448 (rank : 46)	θ value	0.00134147 (rank : 45)
Query Neighborhood Hits	161	Target Neighborhood Hits	94	Shared Neighborhood Hits	45
SwissProt Accessions	Q6NT99, Q9CW48	Gene names	Dusp23, Ldp3
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3).

EPM2A_MOUSE
NC score	0.281063 (rank : 47)	θ value	0.21417 (rank : 69)
Query Neighborhood Hits	161	Target Neighborhood Hits	47	Shared Neighborhood Hits	37
SwissProt Accessions	Q9WUA5, Q8BY80	Gene names	Epm2a
Domain Architecture	No domain graphic available
Description	Laforin (EC 3.1.3.48) (EC 3.1.3.16) (Lafora PTPase) (LAFPTPase).

EPM2A_HUMAN
NC score	0.280196 (rank : 48)	θ value	0.163984 (rank : 64)
Query Neighborhood Hits	161	Target Neighborhood Hits	47	Shared Neighborhood Hits	38
SwissProt Accessions	O95278, O95483, Q8IU96, Q8IX24, Q8IX25, Q9BS66, Q9UEN2	Gene names	EPM2A
Domain Architecture	No domain graphic available
Description	Laforin (EC 3.1.3.48) (EC 3.1.3.16) (Lafora PTPase) (LAFPTPase).

CC14B_MOUSE
NC score	0.280109 (rank : 49)	θ value	0.0563607 (rank : 56)
Query Neighborhood Hits	161	Target Neighborhood Hits	103	Shared Neighborhood Hits	51
SwissProt Accessions	Q6PFY9, Q80WC4, Q8BLV5	Gene names	Cdc14b
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

CC14A_MOUSE
NC score	0.258645 (rank : 50)	θ value	0.62314 (rank : 85)
Query Neighborhood Hits	161	Target Neighborhood Hits	117	Shared Neighborhood Hits	53
SwissProt Accessions	Q6GQT0, Q8BZ66	Gene names	Cdc14a
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

CC14A_HUMAN
NC score	0.255633 (rank : 51)	θ value	0.62314 (rank : 84)
Query Neighborhood Hits	161	Target Neighborhood Hits	133	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UNH5, O43171, O60727, O60728, Q8IXX0	Gene names	CDC14A
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

TP4A3_HUMAN
NC score	0.157625 (rank : 52)	θ value	0.365318 (rank : 80)
Query Neighborhood Hits	161	Target Neighborhood Hits	62	Shared Neighborhood Hits	37
SwissProt Accessions	O75365, Q8IVN5, Q99849, Q9BTW5	Gene names	PTP4A3, PRL3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3) (PRL-R).

TP4A3_MOUSE
NC score	0.153764 (rank : 53)	θ value	0.365318 (rank : 81)
Query Neighborhood Hits	161	Target Neighborhood Hits	60	Shared Neighborhood Hits	37
SwissProt Accessions	Q9D658, O70275, Q3T9Z5, Q9CTC8	Gene names	Ptp4a3, Prl3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3).

TP4A1_HUMAN
NC score	0.130843 (rank : 54)	θ value	0.21417 (rank : 72)
Query Neighborhood Hits	161	Target Neighborhood Hits	68	Shared Neighborhood Hits	33
SwissProt Accessions	Q93096, O00648, Q49A54	Gene names	PTP4A1, PRL1, PTPCAAX1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1) (PTP(CAAXI)).

TP4A1_MOUSE
NC score	0.130843 (rank : 55)	θ value	0.21417 (rank : 73)
Query Neighborhood Hits	161	Target Neighborhood Hits	68	Shared Neighborhood Hits	33
SwissProt Accessions	Q63739, O09097, O09154, Q3UFU9	Gene names	Ptp4a1, Prl1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1).

TP4A2_HUMAN
NC score	0.129509 (rank : 56)	θ value	0.0961366 (rank : 60)
Query Neighborhood Hits	161	Target Neighborhood Hits	56	Shared Neighborhood Hits	28
SwissProt Accessions	Q12974, O00649, Q15197, Q15259, Q15260, Q15261	Gene names	PTP4A2, PRL2, PTPCAAX2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2) (PTP(CAAXII)) (HU-PP-1) (OV-1).

TP4A2_MOUSE
NC score	0.129509 (rank : 57)	θ value	0.0961366 (rank : 61)
Query Neighborhood Hits	161	Target Neighborhood Hits	56	Shared Neighborhood Hits	28
SwissProt Accessions	O70274, Q3U1K7	Gene names	Ptp4a2, Prl2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2).

DUS11_MOUSE
NC score	0.105361 (rank : 58)	θ value	0.365318 (rank : 77)
Query Neighborhood Hits	161	Target Neighborhood Hits	41	Shared Neighborhood Hits	22
SwissProt Accessions	Q6NXK5, Q8BTR4, Q8BYE4	Gene names	Dusp11, Pir1
Domain Architecture	No domain graphic available
Description	RNA/RNP complex-1-interacting phosphatase (EC 3.1.3.-) (Phosphatase that interacts with RNA/RNP complex 1) (Dual specificity protein phosphatase 11).

CT174_HUMAN
NC score	0.076630 (rank : 59)	θ value	0.00228821 (rank : 47)
Query Neighborhood Hits	161	Target Neighborhood Hits	181	Shared Neighborhood Hits	18
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

OGFR_HUMAN
NC score	0.071056 (rank : 60)	θ value	2.88788e-06 (rank : 41)
Query Neighborhood Hits	161	Target Neighborhood Hits	1582	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PRP1_HUMAN
NC score	0.064385 (rank : 61)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	161	Target Neighborhood Hits	385	Shared Neighborhood Hits	48
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRP2_MOUSE
NC score	0.062964 (rank : 62)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	161	Target Neighborhood Hits	347	Shared Neighborhood Hits	45
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRB4S_HUMAN
NC score	0.061931 (rank : 63)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	161	Target Neighborhood Hits	330	Shared Neighborhood Hits	45
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PRB3_HUMAN
NC score	0.057070 (rank : 64)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	161	Target Neighborhood Hits	318	Shared Neighborhood Hits	43
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

CG1_HUMAN
NC score	0.051765 (rank : 65)	θ value	0.0330416 (rank : 55)
Query Neighborhood Hits	161	Target Neighborhood Hits	222	Shared Neighborhood Hits	14
SwissProt Accessions	Q13495	Gene names	CXorf6, CG1
Domain Architecture	No domain graphic available
Description	CG1 protein (F18).

SNPC4_HUMAN
NC score	0.049029 (rank : 66)	θ value	0.0252991 (rank : 54)
Query Neighborhood Hits	161	Target Neighborhood Hits	589	Shared Neighborhood Hits	34
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

PRRT3_HUMAN
NC score	0.048432 (rank : 67)	θ value	0.00509761 (rank : 51)
Query Neighborhood Hits	161	Target Neighborhood Hits	998	Shared Neighborhood Hits	52
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

BSN_MOUSE
NC score	0.044920 (rank : 68)	θ value	0.125558 (rank : 62)
Query Neighborhood Hits	161	Target Neighborhood Hits	2057	Shared Neighborhood Hits	75
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

MUC1_HUMAN
NC score	0.042343 (rank : 69)	θ value	0.000461057 (rank : 44)
Query Neighborhood Hits	161	Target Neighborhood Hits	975	Shared Neighborhood Hits	48
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

PKHG4_HUMAN
NC score	0.040348 (rank : 70)	θ value	0.00869519 (rank : 52)
Query Neighborhood Hits	161	Target Neighborhood Hits	200	Shared Neighborhood Hits	11
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

ZN750_MOUSE
NC score	0.037614 (rank : 71)	θ value	0.163984 (rank : 67)
Query Neighborhood Hits	161	Target Neighborhood Hits	346	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

K1802_MOUSE
NC score	0.036550 (rank : 72)	θ value	0.00228821 (rank : 48)
Query Neighborhood Hits	161	Target Neighborhood Hits	1596	Shared Neighborhood Hits	57
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

NUP53_MOUSE
NC score	0.033449 (rank : 73)	θ value	0.365318 (rank : 79)
Query Neighborhood Hits	161	Target Neighborhood Hits	94	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R4R6, Q9D7J2	Gene names	Nup35, Mp44, Nup53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

MILK2_HUMAN
NC score	0.033408 (rank : 74)	θ value	0.0563607 (rank : 58)
Query Neighborhood Hits	161	Target Neighborhood Hits	457	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

MILK1_HUMAN
NC score	0.033123 (rank : 75)	θ value	2.36792 (rank : 113)
Query Neighborhood Hits	161	Target Neighborhood Hits	427	Shared Neighborhood Hits	38
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

ZN395_HUMAN
NC score	0.032702 (rank : 76)	θ value	0.813845 (rank : 93)
Query Neighborhood Hits	161	Target Neighborhood Hits	64	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H8N7, Q6F6H2, Q9BY72, Q9NPB2, Q9NS57, Q9NS58, Q9NS59	Gene names	ZNF395, HDBP2, PBF
Domain Architecture	No domain graphic available
Description	Zinc finger protein 395 (Papillomavirus-binding factor) (Papillomavirus regulatory factor 1) (PRF-1) (Huntington disease gene regulatory region-binding protein 2) (HDBP-2) (HD gene regulatory region-binding protein 2) (HD-regulating factor 2) (HDRF-2).

JPH2_HUMAN
NC score	0.031954 (rank : 77)	θ value	0.21417 (rank : 70)
Query Neighborhood Hits	161	Target Neighborhood Hits	639	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

BCL9_MOUSE
NC score	0.030900 (rank : 78)	θ value	6.88961 (rank : 135)
Query Neighborhood Hits	161	Target Neighborhood Hits	770	Shared Neighborhood Hits	51
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

IL3B2_MOUSE
NC score	0.029872 (rank : 79)	θ value	0.47712 (rank : 82)
Query Neighborhood Hits	161	Target Neighborhood Hits	372	Shared Neighborhood Hits	21
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

IL3RB_MOUSE
NC score	0.029805 (rank : 80)	θ value	0.62314 (rank : 87)
Query Neighborhood Hits	161	Target Neighborhood Hits	355	Shared Neighborhood Hits	23
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

IASPP_MOUSE
NC score	0.029219 (rank : 81)	θ value	0.365318 (rank : 78)
Query Neighborhood Hits	161	Target Neighborhood Hits	1024	Shared Neighborhood Hits	47
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

K0310_HUMAN
NC score	0.029060 (rank : 82)	θ value	4.03905 (rank : 122)
Query Neighborhood Hits	161	Target Neighborhood Hits	420	Shared Neighborhood Hits	28
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

MEF2B_MOUSE
NC score	0.028730 (rank : 83)	θ value	0.125558 (rank : 63)
Query Neighborhood Hits	161	Target Neighborhood Hits	218	Shared Neighborhood Hits	19
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

SAPS1_HUMAN
NC score	0.028718 (rank : 84)	θ value	0.279714 (rank : 75)
Query Neighborhood Hits	161	Target Neighborhood Hits	704	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

T22D4_HUMAN
NC score	0.028671 (rank : 85)	θ value	1.06291 (rank : 99)
Query Neighborhood Hits	161	Target Neighborhood Hits	403	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

TCOF_HUMAN
NC score	0.028649 (rank : 86)	θ value	5.27518 (rank : 133)
Query Neighborhood Hits	161	Target Neighborhood Hits	543	Shared Neighborhood Hits	25
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

EFS_MOUSE
NC score	0.028315 (rank : 87)	θ value	0.813845 (rank : 90)
Query Neighborhood Hits	161	Target Neighborhood Hits	389	Shared Neighborhood Hits	27
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

BAT2_MOUSE
NC score	0.028291 (rank : 88)	θ value	5.27518 (rank : 126)
Query Neighborhood Hits	161	Target Neighborhood Hits	947	Shared Neighborhood Hits	55
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

ICAM4_HUMAN
NC score	0.027920 (rank : 89)	θ value	1.38821 (rank : 100)
Query Neighborhood Hits	161	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q14773, Q14771, Q14772, Q16375	Gene names	ICAM4, LW
Domain Architecture
Description	Intercellular adhesion molecule 4 precursor (ICAM-4) (Landsteiner- Wiener blood group glycoprotein) (LW blood group protein) (CD242 antigen).

CO5A2_HUMAN
NC score	0.027618 (rank : 90)	θ value	0.21417 (rank : 68)
Query Neighborhood Hits	161	Target Neighborhood Hits	760	Shared Neighborhood Hits	43
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

BIN1_HUMAN
NC score	0.027444 (rank : 91)	θ value	0.279714 (rank : 74)
Query Neighborhood Hits	161	Target Neighborhood Hits	335	Shared Neighborhood Hits	19
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

T22D4_MOUSE
NC score	0.026960 (rank : 92)	θ value	5.27518 (rank : 132)
Query Neighborhood Hits	161	Target Neighborhood Hits	92	Shared Neighborhood Hits	16
SwissProt Accessions	Q9EQN3	Gene names	Tsc22d4, Tilz2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2).

CABIN_HUMAN
NC score	0.026756 (rank : 93)	θ value	4.03905 (rank : 120)
Query Neighborhood Hits	161	Target Neighborhood Hits	490	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CASC3_MOUSE
NC score	0.026495 (rank : 94)	θ value	1.81305 (rank : 104)
Query Neighborhood Hits	161	Target Neighborhood Hits	333	Shared Neighborhood Hits	21
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

BCL9_HUMAN
NC score	0.026211 (rank : 95)	θ value	6.88961 (rank : 134)
Query Neighborhood Hits	161	Target Neighborhood Hits	1008	Shared Neighborhood Hits	52
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

NUP53_HUMAN
NC score	0.025092 (rank : 96)	θ value	6.88961 (rank : 141)
Query Neighborhood Hits	161	Target Neighborhood Hits	156	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NFH5, Q4ZFZ9, Q53S95, Q8TDJ1	Gene names	NUP35, MP44, NUP53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

MUCDL_HUMAN
NC score	0.024935 (rank : 97)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	161	Target Neighborhood Hits	777	Shared Neighborhood Hits	47
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

SSBP4_HUMAN
NC score	0.023406 (rank : 98)	θ value	0.813845 (rank : 91)
Query Neighborhood Hits	161	Target Neighborhood Hits	753	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

RP1L1_HUMAN
NC score	0.023316 (rank : 99)	θ value	8.99809 (rank : 158)
Query Neighborhood Hits	161	Target Neighborhood Hits	1072	Shared Neighborhood Hits	44
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

DTNB_MOUSE
NC score	0.021368 (rank : 100)	θ value	0.0563607 (rank : 57)
Query Neighborhood Hits	161	Target Neighborhood Hits	263	Shared Neighborhood Hits	3
SwissProt Accessions	O70585, O70563, Q9CTZ1	Gene names	Dtnb
Domain Architecture
Description	Dystrobrevin beta (Beta-dystrobrevin) (DTN-B) (MDTN-B).

TARA_HUMAN
NC score	0.021314 (rank : 101)	θ value	0.163984 (rank : 66)
Query Neighborhood Hits	161	Target Neighborhood Hits	1626	Shared Neighborhood Hits	46
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

CSKI1_HUMAN
NC score	0.020456 (rank : 102)	θ value	3.0926 (rank : 116)
Query Neighborhood Hits	161	Target Neighborhood Hits	997	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

MISS_MOUSE
NC score	0.019969 (rank : 103)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	161	Target Neighborhood Hits	444	Shared Neighborhood Hits	30
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

DNMT1_MOUSE
NC score	0.019268 (rank : 104)	θ value	2.36792 (rank : 111)
Query Neighborhood Hits	161	Target Neighborhood Hits	137	Shared Neighborhood Hits	4
SwissProt Accessions	P13864, P97413, Q80ZU3, Q9CSC6, Q9QXX6	Gene names	Dnmt1, Dnmt, Met1, Uim
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase MmuI) (DNA MTase MmuI) (MCMT) (M.MmuI) (Met-1).

MLL3_HUMAN
NC score	0.018894 (rank : 105)	θ value	0.62314 (rank : 88)
Query Neighborhood Hits	161	Target Neighborhood Hits	1644	Shared Neighborhood Hits	46
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

COBA2_MOUSE
NC score	0.018444 (rank : 106)	θ value	1.81305 (rank : 107)
Query Neighborhood Hits	161	Target Neighborhood Hits	501	Shared Neighborhood Hits	35
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

PHLPP_HUMAN
NC score	0.018373 (rank : 107)	θ value	1.06291 (rank : 94)
Query Neighborhood Hits	161	Target Neighborhood Hits	604	Shared Neighborhood Hits	35
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

PHLB1_MOUSE
NC score	0.018336 (rank : 108)	θ value	0.21417 (rank : 71)
Query Neighborhood Hits	161	Target Neighborhood Hits	678	Shared Neighborhood Hits	23
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

NFH_MOUSE
NC score	0.017965 (rank : 109)	θ value	0.62314 (rank : 89)
Query Neighborhood Hits	161	Target Neighborhood Hits	2247	Shared Neighborhood Hits	64
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

NU133_HUMAN
NC score	0.017945 (rank : 110)	θ value	1.81305 (rank : 108)
Query Neighborhood Hits	161	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WUM0, Q9H9W2, Q9NV71, Q9NVC4	Gene names	NUP133
Domain Architecture
Description	Nuclear pore complex protein Nup133 (Nucleoporin Nup133) (133 kDa nucleoporin).

PTPRE_HUMAN
NC score	0.017787 (rank : 111)	θ value	5.27518 (rank : 130)
Query Neighborhood Hits	161	Target Neighborhood Hits	92	Shared Neighborhood Hits	24
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

CO4A1_HUMAN
NC score	0.017186 (rank : 112)	θ value	1.81305 (rank : 106)
Query Neighborhood Hits	161	Target Neighborhood Hits	425	Shared Neighborhood Hits	34
SwissProt Accessions	P02462	Gene names	COL4A1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

ZIMP7_MOUSE
NC score	0.017185 (rank : 113)	θ value	2.36792 (rank : 115)
Query Neighborhood Hits	161	Target Neighborhood Hits	566	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

PER3_HUMAN
NC score	0.016909 (rank : 114)	θ value	1.81305 (rank : 109)
Query Neighborhood Hits	161	Target Neighborhood Hits	479	Shared Neighborhood Hits	31
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

RGS3_HUMAN
NC score	0.016133 (rank : 115)	θ value	1.38821 (rank : 102)
Query Neighborhood Hits	161	Target Neighborhood Hits	1375	Shared Neighborhood Hits	52
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

PTPRA_MOUSE
NC score	0.016067 (rank : 116)	θ value	8.99809 (rank : 156)
Query Neighborhood Hits	161	Target Neighborhood Hits	93	Shared Neighborhood Hits	21
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PSL1_HUMAN
NC score	0.015571 (rank : 117)	θ value	4.03905 (rank : 125)
Query Neighborhood Hits	161	Target Neighborhood Hits	650	Shared Neighborhood Hits	25
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

CO5A3_HUMAN
NC score	0.014667 (rank : 118)	θ value	4.03905 (rank : 121)
Query Neighborhood Hits	161	Target Neighborhood Hits	433	Shared Neighborhood Hits	31
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

CEL_HUMAN
NC score	0.014482 (rank : 119)	θ value	1.81305 (rank : 105)
Query Neighborhood Hits	161	Target Neighborhood Hits	896	Shared Neighborhood Hits	35
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

RUSC2_MOUSE
NC score	0.014437 (rank : 120)	θ value	8.99809 (rank : 159)
Query Neighborhood Hits	161	Target Neighborhood Hits	305	Shared Neighborhood Hits	26
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

PTPRE_MOUSE
NC score	0.014093 (rank : 121)	θ value	6.88961 (rank : 142)
Query Neighborhood Hits	161	Target Neighborhood Hits	86	Shared Neighborhood Hits	20
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

CAC1G_HUMAN
NC score	0.012961 (rank : 122)	θ value	0.365318 (rank : 76)
Query Neighborhood Hits	161	Target Neighborhood Hits	587	Shared Neighborhood Hits	26
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

LAG3_MOUSE
NC score	0.012704 (rank : 123)	θ value	4.03905 (rank : 123)
Query Neighborhood Hits	161	Target Neighborhood Hits	117	Shared Neighborhood Hits	4
SwissProt Accessions	Q61790, Q0VBL2	Gene names	Lag3
Domain Architecture
Description	Lymphocyte activation gene 3 protein precursor (LAG-3) (CD223 antigen).

GA2L2_MOUSE
NC score	0.011943 (rank : 124)	θ value	6.88961 (rank : 140)
Query Neighborhood Hits	161	Target Neighborhood Hits	395	Shared Neighborhood Hits	23
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

K2027_MOUSE
NC score	0.011837 (rank : 125)	θ value	5.27518 (rank : 127)
Query Neighborhood Hits	161	Target Neighborhood Hits	106	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BWS5, Q69Z30	Gene names	Kiaa2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

PKD1_HUMAN
NC score	0.011406 (rank : 126)	θ value	1.06291 (rank : 95)
Query Neighborhood Hits	161	Target Neighborhood Hits	387	Shared Neighborhood Hits	4
SwissProt Accessions	P98161, Q15140, Q15141	Gene names	PKD1
Domain Architecture
Description	Polycystin-1 precursor (Autosomal dominant polycystic kidney disease protein 1).

WDFY3_HUMAN
NC score	0.011107 (rank : 127)	θ value	0.813845 (rank : 92)
Query Neighborhood Hits	161	Target Neighborhood Hits	348	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IZQ1, Q4W5K5, Q6P0Q5, Q8N1T2, Q96BS7, Q96N85, Q9Y2J7	Gene names	WDFY3, KIAA0993
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy).

RHBD1_HUMAN
NC score	0.010748 (rank : 128)	θ value	3.0926 (rank : 117)
Query Neighborhood Hits	161	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	O75783, Q9NQ85	Gene names	RHBDL1, RHBDL
Domain Architecture
Description	Rhomboid-related protein 1 (EC 3.4.21.105) (RRP) (Rhomboid-like protein 1).

FGD1_MOUSE
NC score	0.010479 (rank : 129)	θ value	6.88961 (rank : 138)
Query Neighborhood Hits	161	Target Neighborhood Hits	387	Shared Neighborhood Hits	27
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

BRD8_MOUSE
NC score	0.010176 (rank : 130)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	161	Target Neighborhood Hits	422	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

RPC2_MOUSE
NC score	0.009384 (rank : 131)	θ value	6.88961 (rank : 144)
Query Neighborhood Hits	161	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	P59470, Q6NVF3	Gene names	Polr3b
Domain Architecture	No domain graphic available
Description	DNA-directed RNA polymerase III subunit 127.6 kDa polypeptide (EC 2.7.7.6) (RNA polymerase III subunit 2) (RPC2).

RPC2_HUMAN
NC score	0.009383 (rank : 132)	θ value	6.88961 (rank : 143)
Query Neighborhood Hits	161	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NW08, Q9NW59	Gene names	POLR3B
Domain Architecture
Description	DNA-directed RNA polymerase III subunit 127.6 kDa polypeptide (EC 2.7.7.6) (RNA polymerase III subunit 2) (RPC2).

SPEG_MOUSE
NC score	0.009113 (rank : 133)	θ value	0.47712 (rank : 83)
Query Neighborhood Hits	161	Target Neighborhood Hits	1959	Shared Neighborhood Hits	60
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

USBP1_HUMAN
NC score	0.008742 (rank : 134)	θ value	6.88961 (rank : 145)
Query Neighborhood Hits	161	Target Neighborhood Hits	188	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N6Y0, Q8NBX7, Q96KH3, Q9BYI8	Gene names	USHBP1, AIEBP, MCC2
Domain Architecture	No domain graphic available
Description	USH1C-binding protein 1 (Usher syndrome type-1C protein-binding protein 1) (MCC-2) (AIE-75 binding protein).

EHMT2_MOUSE
NC score	0.008603 (rank : 135)	θ value	0.62314 (rank : 86)
Query Neighborhood Hits	161	Target Neighborhood Hits	750	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

PDZD2_HUMAN
NC score	0.008553 (rank : 136)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	161	Target Neighborhood Hits	772	Shared Neighborhood Hits	32
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

PTCD1_HUMAN
NC score	0.008078 (rank : 137)	θ value	8.99809 (rank : 155)
Query Neighborhood Hits	161	Target Neighborhood Hits	52	Shared Neighborhood Hits	5
SwissProt Accessions	O75127, Q66K60, Q9UDV2	Gene names	PTCD1, KIAA0632
Domain Architecture	No domain graphic available
Description	Pentatricopeptide repeat protein 1.

OBSCN_HUMAN
NC score	0.007988 (rank : 138)	θ value	0.163984 (rank : 65)
Query Neighborhood Hits	161	Target Neighborhood Hits	1931	Shared Neighborhood Hits	50
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

SYIM_HUMAN
NC score	0.007648 (rank : 139)	θ value	5.27518 (rank : 131)
Query Neighborhood Hits	161	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NSE4, Q6PI85, Q7L439, Q86WU9, Q96D91	Gene names	IARS2
Domain Architecture	No domain graphic available
Description	Isoleucyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.5) (Isoleucine--tRNA ligase) (IleRS).

ITAM_HUMAN
NC score	0.007421 (rank : 140)	θ value	2.36792 (rank : 112)
Query Neighborhood Hits	161	Target Neighborhood Hits	78	Shared Neighborhood Hits	3
SwissProt Accessions	P11215	Gene names	ITGAM, CD11B, CR3A
Domain Architecture
Description	Integrin alpha-M precursor (Cell surface glycoprotein MAC-1 alpha subunit) (CR-3 alpha chain) (Leukocyte adhesion receptor MO1) (Neutrophil adherence receptor) (CD11b antigen).

SC6A5_MOUSE
NC score	0.007105 (rank : 141)	θ value	1.06291 (rank : 96)
Query Neighborhood Hits	161	Target Neighborhood Hits	135	Shared Neighborhood Hits	7
SwissProt Accessions	Q761V0, Q8CFM5, Q91ZQ2	Gene names	Slc6a5, Glyt2
Domain Architecture	No domain graphic available
Description	Sodium- and chloride-dependent glycine transporter 2 (GlyT2) (GlyT-2) (Solute carrier family 6 member 5).

DCX_MOUSE
NC score	0.006965 (rank : 142)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	161	Target Neighborhood Hits	124	Shared Neighborhood Hits	9
SwissProt Accessions	O88809	Gene names	Dcx, Dcn
Domain Architecture
Description	Neuronal migration protein doublecortin (Lissencephalin-X) (Lis-X) (Doublin).

KCD18_HUMAN
NC score	0.006443 (rank : 143)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	161	Target Neighborhood Hits	117	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PI47, Q53T21, Q6NW26, Q6PCD8, Q8N9B7, Q96N73	Gene names	KCTD18
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD18.

PTPRN_HUMAN
NC score	0.006115 (rank : 144)	θ value	8.99809 (rank : 157)
Query Neighborhood Hits	161	Target Neighborhood Hits	156	Shared Neighborhood Hits	18
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

MK15_HUMAN
NC score	0.005731 (rank : 145)	θ value	0.0563607 (rank : 59)
Query Neighborhood Hits	161	Target Neighborhood Hits	1038	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

ULK1_MOUSE
NC score	0.005703 (rank : 146)	θ value	0.0148317 (rank : 53)
Query Neighborhood Hits	161	Target Neighborhood Hits	1214	Shared Neighborhood Hits	33
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

ZEP1_MOUSE
NC score	0.005657 (rank : 147)	θ value	2.36792 (rank : 114)
Query Neighborhood Hits	161	Target Neighborhood Hits	1063	Shared Neighborhood Hits	27
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

ULK1_HUMAN
NC score	0.004901 (rank : 148)	θ value	3.0926 (rank : 119)
Query Neighborhood Hits	161	Target Neighborhood Hits	1121	Shared Neighborhood Hits	34
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

ZN414_MOUSE
NC score	0.004585 (rank : 149)	θ value	8.99809 (rank : 161)
Query Neighborhood Hits	161	Target Neighborhood Hits	473	Shared Neighborhood Hits	7
SwissProt Accessions	Q9DCK4, Q8CHU9	Gene names	Znf414, Zfp414
Domain Architecture	No domain graphic available
Description	Zinc finger protein 414.

SMAD6_MOUSE
NC score	0.004549 (rank : 150)	θ value	8.99809 (rank : 160)
Query Neighborhood Hits	161	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	O35182, Q9CW62	Gene names	Smad6, Madh6, Madh7, Msmad6
Domain Architecture
Description	Mothers against decapentaplegic homolog 6 (SMAD 6) (Mothers against DPP homolog 6) (Smad6) (Mad homolog 7).

ROBO3_MOUSE
NC score	0.004308 (rank : 151)	θ value	3.0926 (rank : 118)
Query Neighborhood Hits	161	Target Neighborhood Hits	524	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

AATK_HUMAN
NC score	0.004290 (rank : 152)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	161	Target Neighborhood Hits	1243	Shared Neighborhood Hits	42
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

TEX14_MOUSE
NC score	0.003559 (rank : 153)	θ value	1.38821 (rank : 103)
Query Neighborhood Hits	161	Target Neighborhood Hits	1333	Shared Neighborhood Hits	18
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

MAST1_HUMAN
NC score	0.003287 (rank : 154)	θ value	5.27518 (rank : 128)
Query Neighborhood Hits	161	Target Neighborhood Hits	1146	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MAST1_MOUSE
NC score	0.003198 (rank : 155)	θ value	5.27518 (rank : 129)
Query Neighborhood Hits	161	Target Neighborhood Hits	1123	Shared Neighborhood Hits	30
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

PAK4_MOUSE
NC score	0.002702 (rank : 156)	θ value	1.38821 (rank : 101)
Query Neighborhood Hits	161	Target Neighborhood Hits	1098	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

MAST2_HUMAN
NC score	0.002432 (rank : 157)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	161	Target Neighborhood Hits	1189	Shared Neighborhood Hits	35
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MAST2_MOUSE
NC score	0.002073 (rank : 158)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	161	Target Neighborhood Hits	1110	Shared Neighborhood Hits	28
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MEFV_HUMAN
NC score	0.001860 (rank : 159)	θ value	4.03905 (rank : 124)
Query Neighborhood Hits	161	Target Neighborhood Hits	431	Shared Neighborhood Hits	10
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

FOXC2_HUMAN
NC score	0.001280 (rank : 160)	θ value	6.88961 (rank : 139)
Query Neighborhood Hits	161	Target Neighborhood Hits	236	Shared Neighborhood Hits	11
SwissProt Accessions	Q99958	Gene names	FOXC2, FKHL14, MFH1
Domain Architecture
Description	Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14).

MYO9B_HUMAN
NC score	0.000840 (rank : 161)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	161	Target Neighborhood Hits	641	Shared Neighborhood Hits	19
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

SP5_HUMAN
NC score	0.000089 (rank : 162)	θ value	1.06291 (rank : 97)
Query Neighborhood Hits	161	Target Neighborhood Hits	832	Shared Neighborhood Hits	18
SwissProt Accessions	Q6BEB4	Gene names	SP5
Domain Architecture	No domain graphic available
Description	Transcription factor Sp5.

SP5_MOUSE
NC score	0.000074 (rank : 163)	θ value	1.06291 (rank : 98)
Query Neighborhood Hits	161	Target Neighborhood Hits	821	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JHX2	Gene names	Sp5
Domain Architecture
Description	Transcription factor Sp5.

KLF1_MOUSE
NC score	-0.002657 (rank : 164)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	161	Target Neighborhood Hits	714	Shared Neighborhood Hits	13
SwissProt Accessions	P46099, O70261	Gene names	Klf1, Elkf
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 1 (Erythroid krueppel-like transcription factor) (EKLF) (Erythroid transcription factor).

5HT7R_HUMAN
NC score	-0.003517 (rank : 165)	θ value	2.36792 (rank : 110)
Query Neighborhood Hits	161	Target Neighborhood Hits	848	Shared Neighborhood Hits	2
SwissProt Accessions	P34969, P78336, P78372, P78516	Gene names	HTR7
Domain Architecture
Description	5-hydroxytryptamine 7 receptor (5-HT-7) (Serotonin receptor 7) (5-HT- X) (5HT7).