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Network neighborhood for query Sequence : GCSP_HUMAN

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GCSP_HUMAN
SwissProt Accessions	P23378	Gene names	GLDC, GCSP
Domain Architecture
Description	Glycine dehydrogenase [decarboxylating], mitochondrial precursor (EC 1.4.4.2) (Glycine decarboxylase) (Glycine cleavage system P- protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GCSP_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	P23378	Gene names	GLDC, GCSP
Domain Architecture
Description	Glycine dehydrogenase [decarboxylating], mitochondrial precursor (EC 1.4.4.2) (Glycine decarboxylase) (Glycine cleavage system P- protein).

GCSP_MOUSE
θ value	0 (rank : 2)	NC score	0.997134 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	Q91W43	Gene names	Gldc
Domain Architecture
Description	Glycine dehydrogenase [decarboxylating], mitochondrial precursor (EC 1.4.4.2) (Glycine decarboxylase) (Glycine cleavage system P- protein).

SGPL1_MOUSE
θ value	0.00390308 (rank : 3)	NC score	0.144513 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R0X7, O54955, Q8C942	Gene names	Sgpl1
Domain Architecture
Description	Sphingosine-1-phosphate lyase 1 (EC 4.1.2.27) (SP-lyase) (mSPL) (Sphingosine-1-phosphate aldolase).

PIWL4_HUMAN
θ value	0.21417 (rank : 4)	NC score	0.035618 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z3Z4, Q68CZ4, Q8N8G9, Q8N9V8, Q8NEH2	Gene names	PIWIL4, HILI2, PIWI
Domain Architecture	No domain graphic available
Description	Piwi-like protein 4.

FBX38_HUMAN
θ value	1.06291 (rank : 5)	NC score	0.047711 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	141	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PIJ6, Q6PK72, Q7Z2U0, Q86VN3, Q9BXY6, Q9H837, Q9HC40	Gene names	FBXO38
Domain Architecture	No domain graphic available
Description	F-box only protein 38 (Modulator of KLF7 activity homolog) (MoKA).

SGPL1_HUMAN
θ value	1.06291 (rank : 6)	NC score	0.083034 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	O95470, Q7Z732, Q9ULG8, Q9UN89	Gene names	SGPL1, KIAA1252
Domain Architecture
Description	Sphingosine-1-phosphate lyase 1 (EC 4.1.2.27) (SP-lyase) (hSPL) (Sphingosine-1-phosphate aldolase).

ARSG_MOUSE
θ value	1.38821 (rank : 7)	NC score	0.040830 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q3TYD4, Q5XFU5, Q69ZT6, Q8CHS3, Q8VBZ5, Q9D3B4	Gene names	Arsg, Kiaa1001
Domain Architecture	No domain graphic available
Description	Arylsulfatase G precursor (EC 3.1.6.-) (ASG).

CTNL1_MOUSE
θ value	1.81305 (rank : 8)	NC score	0.038015 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	91	Shared Neighborhood Hits	3
SwissProt Accessions	O88327, Q810J3	Gene names	Ctnnal1, Catnal1
Domain Architecture	No domain graphic available
Description	Alpha-catulin (Catenin alpha-like protein 1) (Alpha-catenin-related protein) (ACRP).

FBX38_MOUSE
θ value	2.36792 (rank : 9)	NC score	0.045631 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BMI0, Q8BTQ4, Q8C0H4	Gene names	Fbxo38
Domain Architecture	No domain graphic available
Description	F-box only protein 38 (Modulator of KLF7 activity) (MoKA).

FCER2_HUMAN
θ value	3.0926 (rank : 10)	NC score	0.012318 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	213	Shared Neighborhood Hits	2
SwissProt Accessions	P06734	Gene names	FCER2, IGEBF
Domain Architecture
Description	Low affinity immunoglobulin epsilon Fc receptor (Lymphocyte IgE receptor) (Fc-epsilon-RII) (BLAST-2) (Immunoglobulin E-binding factor) (CD23 antigen) [Contains: Low affinity immunoglobulin epsilon Fc receptor membrane-bound form; Low affinity immunoglobulin epsilon Fc receptor soluble form].

ARSG_HUMAN
θ value	4.03905 (rank : 11)	NC score	0.034225 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	Q96EG1, Q6UXF2, Q9Y2K4	Gene names	ARSG, KIAA1001
Domain Architecture	No domain graphic available
Description	Arylsulfatase G precursor (EC 3.1.6.-) (ASG).

M4K2_MOUSE
θ value	4.03905 (rank : 12)	NC score	0.002276 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	843	Shared Neighborhood Hits	2
SwissProt Accessions	Q61161	Gene names	Map4k2, Rab8ip
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Germinal center kinase) (GCK) (Rab8-interacting protein).

ITAM_HUMAN
θ value	5.27518 (rank : 13)	NC score	0.009881 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	78	Shared Neighborhood Hits	3
SwissProt Accessions	P11215	Gene names	ITGAM, CD11B, CR3A
Domain Architecture
Description	Integrin alpha-M precursor (Cell surface glycoprotein MAC-1 alpha subunit) (CR-3 alpha chain) (Leukocyte adhesion receptor MO1) (Neutrophil adherence receptor) (CD11b antigen).

EVI1_HUMAN
θ value	8.99809 (rank : 14)	NC score	0.000537 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	924	Shared Neighborhood Hits	2
SwissProt Accessions	Q03112, Q16122, Q99917	Gene names	EVI1
Domain Architecture
Description	Ecotropic virus integration 1 site protein.

NIPA_HUMAN
θ value	8.99809 (rank : 15)	NC score	0.014739 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q86WB0, Q75MF3, Q75MF4, Q8N330, Q96F75, Q9HA34, Q9NVX4, Q9P0R0	Gene names	ZC3HC1, NIPA
Domain Architecture	No domain graphic available
Description	Nuclear-interacting partner of ALK (Nuclear-interacting partner of anaplastic lymphoma kinase) (hNIPA) (Zinc finger C3HC-type protein 1).

Hits sorted by NC score

GCSP_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	P23378	Gene names	GLDC, GCSP
Domain Architecture
Description	Glycine dehydrogenase [decarboxylating], mitochondrial precursor (EC 1.4.4.2) (Glycine decarboxylase) (Glycine cleavage system P- protein).

GCSP_MOUSE
NC score	0.997134 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	Q91W43	Gene names	Gldc
Domain Architecture
Description	Glycine dehydrogenase [decarboxylating], mitochondrial precursor (EC 1.4.4.2) (Glycine decarboxylase) (Glycine cleavage system P- protein).

SGPL1_MOUSE
NC score	0.144513 (rank : 3)	θ value	0.00390308 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R0X7, O54955, Q8C942	Gene names	Sgpl1
Domain Architecture
Description	Sphingosine-1-phosphate lyase 1 (EC 4.1.2.27) (SP-lyase) (mSPL) (Sphingosine-1-phosphate aldolase).

SGPL1_HUMAN
NC score	0.083034 (rank : 4)	θ value	1.06291 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	O95470, Q7Z732, Q9ULG8, Q9UN89	Gene names	SGPL1, KIAA1252
Domain Architecture
Description	Sphingosine-1-phosphate lyase 1 (EC 4.1.2.27) (SP-lyase) (hSPL) (Sphingosine-1-phosphate aldolase).

FBX38_HUMAN
NC score	0.047711 (rank : 5)	θ value	1.06291 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	141	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PIJ6, Q6PK72, Q7Z2U0, Q86VN3, Q9BXY6, Q9H837, Q9HC40	Gene names	FBXO38
Domain Architecture	No domain graphic available
Description	F-box only protein 38 (Modulator of KLF7 activity homolog) (MoKA).

FBX38_MOUSE
NC score	0.045631 (rank : 6)	θ value	2.36792 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BMI0, Q8BTQ4, Q8C0H4	Gene names	Fbxo38
Domain Architecture	No domain graphic available
Description	F-box only protein 38 (Modulator of KLF7 activity) (MoKA).

ARSG_MOUSE
NC score	0.040830 (rank : 7)	θ value	1.38821 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q3TYD4, Q5XFU5, Q69ZT6, Q8CHS3, Q8VBZ5, Q9D3B4	Gene names	Arsg, Kiaa1001
Domain Architecture	No domain graphic available
Description	Arylsulfatase G precursor (EC 3.1.6.-) (ASG).

CTNL1_MOUSE
NC score	0.038015 (rank : 8)	θ value	1.81305 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	91	Shared Neighborhood Hits	3
SwissProt Accessions	O88327, Q810J3	Gene names	Ctnnal1, Catnal1
Domain Architecture	No domain graphic available
Description	Alpha-catulin (Catenin alpha-like protein 1) (Alpha-catenin-related protein) (ACRP).

PIWL4_HUMAN
NC score	0.035618 (rank : 9)	θ value	0.21417 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z3Z4, Q68CZ4, Q8N8G9, Q8N9V8, Q8NEH2	Gene names	PIWIL4, HILI2, PIWI
Domain Architecture	No domain graphic available
Description	Piwi-like protein 4.

ARSG_HUMAN
NC score	0.034225 (rank : 10)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	Q96EG1, Q6UXF2, Q9Y2K4	Gene names	ARSG, KIAA1001
Domain Architecture	No domain graphic available
Description	Arylsulfatase G precursor (EC 3.1.6.-) (ASG).

NIPA_HUMAN
NC score	0.014739 (rank : 11)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q86WB0, Q75MF3, Q75MF4, Q8N330, Q96F75, Q9HA34, Q9NVX4, Q9P0R0	Gene names	ZC3HC1, NIPA
Domain Architecture	No domain graphic available
Description	Nuclear-interacting partner of ALK (Nuclear-interacting partner of anaplastic lymphoma kinase) (hNIPA) (Zinc finger C3HC-type protein 1).

FCER2_HUMAN
NC score	0.012318 (rank : 12)	θ value	3.0926 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	213	Shared Neighborhood Hits	2
SwissProt Accessions	P06734	Gene names	FCER2, IGEBF
Domain Architecture
Description	Low affinity immunoglobulin epsilon Fc receptor (Lymphocyte IgE receptor) (Fc-epsilon-RII) (BLAST-2) (Immunoglobulin E-binding factor) (CD23 antigen) [Contains: Low affinity immunoglobulin epsilon Fc receptor membrane-bound form; Low affinity immunoglobulin epsilon Fc receptor soluble form].

ITAM_HUMAN
NC score	0.009881 (rank : 13)	θ value	5.27518 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	78	Shared Neighborhood Hits	3
SwissProt Accessions	P11215	Gene names	ITGAM, CD11B, CR3A
Domain Architecture
Description	Integrin alpha-M precursor (Cell surface glycoprotein MAC-1 alpha subunit) (CR-3 alpha chain) (Leukocyte adhesion receptor MO1) (Neutrophil adherence receptor) (CD11b antigen).

M4K2_MOUSE
NC score	0.002276 (rank : 14)	θ value	4.03905 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	843	Shared Neighborhood Hits	2
SwissProt Accessions	Q61161	Gene names	Map4k2, Rab8ip
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Germinal center kinase) (GCK) (Rab8-interacting protein).

EVI1_HUMAN
NC score	0.000537 (rank : 15)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	924	Shared Neighborhood Hits	2
SwissProt Accessions	Q03112, Q16122, Q99917	Gene names	EVI1
Domain Architecture
Description	Ecotropic virus integration 1 site protein.