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Network neighborhood for query Sequence : NIPA_HUMAN

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NIPA_HUMAN
SwissProt Accessions	Q86WB0, Q75MF3, Q75MF4, Q8N330, Q96F75, Q9HA34, Q9NVX4, Q9P0R0	Gene names	ZC3HC1, NIPA
Domain Architecture	No domain graphic available
Description	Nuclear-interacting partner of ALK (Nuclear-interacting partner of anaplastic lymphoma kinase) (hNIPA) (Zinc finger C3HC-type protein 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NIPA_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	37	Target Neighborhood Hits	37	Shared Neighborhood Hits	37
SwissProt Accessions	Q86WB0, Q75MF3, Q75MF4, Q8N330, Q96F75, Q9HA34, Q9NVX4, Q9P0R0	Gene names	ZC3HC1, NIPA
Domain Architecture	No domain graphic available
Description	Nuclear-interacting partner of ALK (Nuclear-interacting partner of anaplastic lymphoma kinase) (hNIPA) (Zinc finger C3HC-type protein 1).

NIPA_MOUSE
θ value	0 (rank : 2)	NC score	0.983741 (rank : 2)
Query Neighborhood Hits	37	Target Neighborhood Hits	50	Shared Neighborhood Hits	15
SwissProt Accessions	Q80YV2, Q3TJE6, Q80Z11, Q8BTW5, Q8CI56, Q8R3U7	Gene names	Zc3hc1, Nipa
Domain Architecture	No domain graphic available
Description	Nuclear-interacting partner of ALK (Nuclear-interacting partner of anaplastic lymphoma kinase) (mNIPA) (Zinc finger C3HC-type protein 1).

ACK1_HUMAN
θ value	0.0736092 (rank : 3)	NC score	0.028383 (rank : 14)
Query Neighborhood Hits	37	Target Neighborhood Hits	1140	Shared Neighborhood Hits	14
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

ACK1_MOUSE
θ value	0.0961366 (rank : 4)	NC score	0.027794 (rank : 16)
Query Neighborhood Hits	37	Target Neighborhood Hits	1080	Shared Neighborhood Hits	13
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

MDC1_HUMAN
θ value	0.0961366 (rank : 5)	NC score	0.059925 (rank : 4)
Query Neighborhood Hits	37	Target Neighborhood Hits	1446	Shared Neighborhood Hits	22
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

ESX1L_HUMAN
θ value	0.163984 (rank : 6)	NC score	0.031617 (rank : 10)
Query Neighborhood Hits	37	Target Neighborhood Hits	498	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N693, Q7Z6K7	Gene names	ESX1L, ESX1R
Domain Architecture
Description	Extraembryonic, spermatogenesis, homeobox 1-like protein.

ZC11A_MOUSE
θ value	0.62314 (rank : 7)	NC score	0.059068 (rank : 5)
Query Neighborhood Hits	37	Target Neighborhood Hits	216	Shared Neighborhood Hits	8
SwissProt Accessions	Q6NZF1, Q6NXW9, Q6PDR6, Q80TU7, Q8C5L5, Q99JN6	Gene names	Zc3h11a, Kiaa0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

LOXL1_HUMAN
θ value	1.06291 (rank : 8)	NC score	0.027801 (rank : 15)
Query Neighborhood Hits	37	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q08397, Q96BW7	Gene names	LOXL1, LOXL
Domain Architecture
Description	Lysyl oxidase homolog 1 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 1) (LOL).

BCOR_HUMAN
θ value	1.38821 (rank : 9)	NC score	0.022662 (rank : 20)
Query Neighborhood Hits	37	Target Neighborhood Hits	609	Shared Neighborhood Hits	9
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

EPN3_MOUSE
θ value	1.38821 (rank : 10)	NC score	0.039664 (rank : 9)
Query Neighborhood Hits	37	Target Neighborhood Hits	312	Shared Neighborhood Hits	13
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

RAPH1_HUMAN
θ value	1.38821 (rank : 11)	NC score	0.040697 (rank : 7)
Query Neighborhood Hits	37	Target Neighborhood Hits	593	Shared Neighborhood Hits	19
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

TM108_MOUSE
θ value	1.81305 (rank : 12)	NC score	0.060430 (rank : 3)
Query Neighborhood Hits	37	Target Neighborhood Hits	336	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

MINT_HUMAN
θ value	2.36792 (rank : 13)	NC score	0.040426 (rank : 8)
Query Neighborhood Hits	37	Target Neighborhood Hits	1291	Shared Neighborhood Hits	17
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

SRRM2_HUMAN
θ value	2.36792 (rank : 14)	NC score	0.047921 (rank : 6)
Query Neighborhood Hits	37	Target Neighborhood Hits	1296	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

HXB2_MOUSE
θ value	3.0926 (rank : 15)	NC score	0.018289 (rank : 25)
Query Neighborhood Hits	37	Target Neighborhood Hits	350	Shared Neighborhood Hits	6
SwissProt Accessions	P0C1T1	Gene names	Hoxb2, Hox-2.8
Domain Architecture	No domain graphic available
Description	Homeobox protein Hox-B2 (Hox-2.8).

SPRE3_HUMAN
θ value	3.0926 (rank : 16)	NC score	0.029889 (rank : 13)
Query Neighborhood Hits	37	Target Neighborhood Hits	65	Shared Neighborhood Hits	5
SwissProt Accessions	Q2MJR0	Gene names	SPRED3
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 3 (Spred-3).

EPN3_HUMAN
θ value	4.03905 (rank : 17)	NC score	0.031596 (rank : 11)
Query Neighborhood Hits	37	Target Neighborhood Hits	197	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H201, Q9BVN6, Q9NWK2	Gene names	EPN3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

MLL2_HUMAN
θ value	4.03905 (rank : 18)	NC score	0.023088 (rank : 19)
Query Neighborhood Hits	37	Target Neighborhood Hits	1788	Shared Neighborhood Hits	24
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MRCKG_MOUSE
θ value	5.27518 (rank : 19)	NC score	0.003341 (rank : 37)
Query Neighborhood Hits	37	Target Neighborhood Hits	1466	Shared Neighborhood Hits	8
SwissProt Accessions	Q80UW5	Gene names	Cdc42bpg
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

PGCB_MOUSE
θ value	5.27518 (rank : 20)	NC score	0.008157 (rank : 34)
Query Neighborhood Hits	37	Target Neighborhood Hits	459	Shared Neighborhood Hits	3
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

SPRE3_MOUSE
θ value	5.27518 (rank : 21)	NC score	0.027517 (rank : 17)
Query Neighborhood Hits	37	Target Neighborhood Hits	111	Shared Neighborhood Hits	6
SwissProt Accessions	Q6P6N5, Q7TNJ8	Gene names	Spred3
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 3 (Spred-3).

SYNJ1_HUMAN
θ value	5.27518 (rank : 22)	NC score	0.020666 (rank : 22)
Query Neighborhood Hits	37	Target Neighborhood Hits	498	Shared Neighborhood Hits	19
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TARA_HUMAN
θ value	5.27518 (rank : 23)	NC score	0.025079 (rank : 18)
Query Neighborhood Hits	37	Target Neighborhood Hits	1626	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

WAPL_MOUSE
θ value	5.27518 (rank : 24)	NC score	0.019979 (rank : 23)
Query Neighborhood Hits	37	Target Neighborhood Hits	158	Shared Neighborhood Hits	2
SwissProt Accessions	Q65Z40, Q6ZQE9	Gene names	Wapal, Kiaa0261, Wapl
Domain Architecture	No domain graphic available
Description	Wings apart-like protein homolog (Dioxin-inducible factor 2) (DIF-2).

ZFY16_MOUSE
θ value	5.27518 (rank : 25)	NC score	0.014598 (rank : 30)
Query Neighborhood Hits	37	Target Neighborhood Hits	108	Shared Neighborhood Hits	3
SwissProt Accessions	Q80U44, Q8BRD2, Q8CG97	Gene names	Zfyve16, Kiaa0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosomal- associated FYVE domain protein).

ATX7_HUMAN
θ value	6.88961 (rank : 26)	NC score	0.019329 (rank : 24)
Query Neighborhood Hits	37	Target Neighborhood Hits	351	Shared Neighborhood Hits	8
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

HCN3_MOUSE
θ value	6.88961 (rank : 27)	NC score	0.008009 (rank : 35)
Query Neighborhood Hits	37	Target Neighborhood Hits	112	Shared Neighborhood Hits	3
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

NBN_MOUSE
θ value	6.88961 (rank : 28)	NC score	0.022088 (rank : 21)
Query Neighborhood Hits	37	Target Neighborhood Hits	125	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R207, O88981, Q3UY57, Q811I6, Q8CCY0, Q9R1X1	Gene names	Nbn, Nbs1
Domain Architecture	No domain graphic available
Description	Nibrin (Nijmegen breakage syndrome protein 1 homolog) (Cell cycle regulatory protein p95).

STK10_HUMAN
θ value	6.88961 (rank : 29)	NC score	0.004236 (rank : 36)
Query Neighborhood Hits	37	Target Neighborhood Hits	1921	Shared Neighborhood Hits	11
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

TARA_MOUSE
θ value	6.88961 (rank : 30)	NC score	0.031441 (rank : 12)
Query Neighborhood Hits	37	Target Neighborhood Hits	1133	Shared Neighborhood Hits	14
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

ANK2_HUMAN
θ value	8.99809 (rank : 31)	NC score	0.009893 (rank : 32)
Query Neighborhood Hits	37	Target Neighborhood Hits	1615	Shared Neighborhood Hits	19
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

CEND3_HUMAN
θ value	8.99809 (rank : 32)	NC score	0.008426 (rank : 33)
Query Neighborhood Hits	37	Target Neighborhood Hits	275	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

GCSP_HUMAN
θ value	8.99809 (rank : 33)	NC score	0.014739 (rank : 29)
Query Neighborhood Hits	37	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	P23378	Gene names	GLDC, GCSP
Domain Architecture
Description	Glycine dehydrogenase [decarboxylating], mitochondrial precursor (EC 1.4.4.2) (Glycine decarboxylase) (Glycine cleavage system P- protein).

IL16_HUMAN
θ value	8.99809 (rank : 34)	NC score	0.016454 (rank : 27)
Query Neighborhood Hits	37	Target Neighborhood Hits	207	Shared Neighborhood Hits	5
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

PDZD2_HUMAN
θ value	8.99809 (rank : 35)	NC score	0.017223 (rank : 26)
Query Neighborhood Hits	37	Target Neighborhood Hits	772	Shared Neighborhood Hits	19
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

RHG25_MOUSE
θ value	8.99809 (rank : 36)	NC score	0.010138 (rank : 31)
Query Neighborhood Hits	37	Target Neighborhood Hits	492	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

TAU_MOUSE
θ value	8.99809 (rank : 37)	NC score	0.015739 (rank : 28)
Query Neighborhood Hits	37	Target Neighborhood Hits	502	Shared Neighborhood Hits	11
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

Hits sorted by NC score

NIPA_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	37	Target Neighborhood Hits	37	Shared Neighborhood Hits	37
SwissProt Accessions	Q86WB0, Q75MF3, Q75MF4, Q8N330, Q96F75, Q9HA34, Q9NVX4, Q9P0R0	Gene names	ZC3HC1, NIPA
Domain Architecture	No domain graphic available
Description	Nuclear-interacting partner of ALK (Nuclear-interacting partner of anaplastic lymphoma kinase) (hNIPA) (Zinc finger C3HC-type protein 1).

NIPA_MOUSE
NC score	0.983741 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	37	Target Neighborhood Hits	50	Shared Neighborhood Hits	15
SwissProt Accessions	Q80YV2, Q3TJE6, Q80Z11, Q8BTW5, Q8CI56, Q8R3U7	Gene names	Zc3hc1, Nipa
Domain Architecture	No domain graphic available
Description	Nuclear-interacting partner of ALK (Nuclear-interacting partner of anaplastic lymphoma kinase) (mNIPA) (Zinc finger C3HC-type protein 1).

TM108_MOUSE
NC score	0.060430 (rank : 3)	θ value	1.81305 (rank : 12)
Query Neighborhood Hits	37	Target Neighborhood Hits	336	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

MDC1_HUMAN
NC score	0.059925 (rank : 4)	θ value	0.0961366 (rank : 5)
Query Neighborhood Hits	37	Target Neighborhood Hits	1446	Shared Neighborhood Hits	22
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

ZC11A_MOUSE
NC score	0.059068 (rank : 5)	θ value	0.62314 (rank : 7)
Query Neighborhood Hits	37	Target Neighborhood Hits	216	Shared Neighborhood Hits	8
SwissProt Accessions	Q6NZF1, Q6NXW9, Q6PDR6, Q80TU7, Q8C5L5, Q99JN6	Gene names	Zc3h11a, Kiaa0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

SRRM2_HUMAN
NC score	0.047921 (rank : 6)	θ value	2.36792 (rank : 14)
Query Neighborhood Hits	37	Target Neighborhood Hits	1296	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

RAPH1_HUMAN
NC score	0.040697 (rank : 7)	θ value	1.38821 (rank : 11)
Query Neighborhood Hits	37	Target Neighborhood Hits	593	Shared Neighborhood Hits	19
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

MINT_HUMAN
NC score	0.040426 (rank : 8)	θ value	2.36792 (rank : 13)
Query Neighborhood Hits	37	Target Neighborhood Hits	1291	Shared Neighborhood Hits	17
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

EPN3_MOUSE
NC score	0.039664 (rank : 9)	θ value	1.38821 (rank : 10)
Query Neighborhood Hits	37	Target Neighborhood Hits	312	Shared Neighborhood Hits	13
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

ESX1L_HUMAN
NC score	0.031617 (rank : 10)	θ value	0.163984 (rank : 6)
Query Neighborhood Hits	37	Target Neighborhood Hits	498	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N693, Q7Z6K7	Gene names	ESX1L, ESX1R
Domain Architecture
Description	Extraembryonic, spermatogenesis, homeobox 1-like protein.

EPN3_HUMAN
NC score	0.031596 (rank : 11)	θ value	4.03905 (rank : 17)
Query Neighborhood Hits	37	Target Neighborhood Hits	197	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H201, Q9BVN6, Q9NWK2	Gene names	EPN3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

TARA_MOUSE
NC score	0.031441 (rank : 12)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	37	Target Neighborhood Hits	1133	Shared Neighborhood Hits	14
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

SPRE3_HUMAN
NC score	0.029889 (rank : 13)	θ value	3.0926 (rank : 16)
Query Neighborhood Hits	37	Target Neighborhood Hits	65	Shared Neighborhood Hits	5
SwissProt Accessions	Q2MJR0	Gene names	SPRED3
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 3 (Spred-3).

ACK1_HUMAN
NC score	0.028383 (rank : 14)	θ value	0.0736092 (rank : 3)
Query Neighborhood Hits	37	Target Neighborhood Hits	1140	Shared Neighborhood Hits	14
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

LOXL1_HUMAN
NC score	0.027801 (rank : 15)	θ value	1.06291 (rank : 8)
Query Neighborhood Hits	37	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q08397, Q96BW7	Gene names	LOXL1, LOXL
Domain Architecture
Description	Lysyl oxidase homolog 1 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 1) (LOL).

ACK1_MOUSE
NC score	0.027794 (rank : 16)	θ value	0.0961366 (rank : 4)
Query Neighborhood Hits	37	Target Neighborhood Hits	1080	Shared Neighborhood Hits	13
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

SPRE3_MOUSE
NC score	0.027517 (rank : 17)	θ value	5.27518 (rank : 21)
Query Neighborhood Hits	37	Target Neighborhood Hits	111	Shared Neighborhood Hits	6
SwissProt Accessions	Q6P6N5, Q7TNJ8	Gene names	Spred3
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 3 (Spred-3).

TARA_HUMAN
NC score	0.025079 (rank : 18)	θ value	5.27518 (rank : 23)
Query Neighborhood Hits	37	Target Neighborhood Hits	1626	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

MLL2_HUMAN
NC score	0.023088 (rank : 19)	θ value	4.03905 (rank : 18)
Query Neighborhood Hits	37	Target Neighborhood Hits	1788	Shared Neighborhood Hits	24
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

BCOR_HUMAN
NC score	0.022662 (rank : 20)	θ value	1.38821 (rank : 9)
Query Neighborhood Hits	37	Target Neighborhood Hits	609	Shared Neighborhood Hits	9
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

NBN_MOUSE
NC score	0.022088 (rank : 21)	θ value	6.88961 (rank : 28)
Query Neighborhood Hits	37	Target Neighborhood Hits	125	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R207, O88981, Q3UY57, Q811I6, Q8CCY0, Q9R1X1	Gene names	Nbn, Nbs1
Domain Architecture	No domain graphic available
Description	Nibrin (Nijmegen breakage syndrome protein 1 homolog) (Cell cycle regulatory protein p95).

SYNJ1_HUMAN
NC score	0.020666 (rank : 22)	θ value	5.27518 (rank : 22)
Query Neighborhood Hits	37	Target Neighborhood Hits	498	Shared Neighborhood Hits	19
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

WAPL_MOUSE
NC score	0.019979 (rank : 23)	θ value	5.27518 (rank : 24)
Query Neighborhood Hits	37	Target Neighborhood Hits	158	Shared Neighborhood Hits	2
SwissProt Accessions	Q65Z40, Q6ZQE9	Gene names	Wapal, Kiaa0261, Wapl
Domain Architecture	No domain graphic available
Description	Wings apart-like protein homolog (Dioxin-inducible factor 2) (DIF-2).

ATX7_HUMAN
NC score	0.019329 (rank : 24)	θ value	6.88961 (rank : 26)
Query Neighborhood Hits	37	Target Neighborhood Hits	351	Shared Neighborhood Hits	8
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

HXB2_MOUSE
NC score	0.018289 (rank : 25)	θ value	3.0926 (rank : 15)
Query Neighborhood Hits	37	Target Neighborhood Hits	350	Shared Neighborhood Hits	6
SwissProt Accessions	P0C1T1	Gene names	Hoxb2, Hox-2.8
Domain Architecture	No domain graphic available
Description	Homeobox protein Hox-B2 (Hox-2.8).

PDZD2_HUMAN
NC score	0.017223 (rank : 26)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	37	Target Neighborhood Hits	772	Shared Neighborhood Hits	19
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

IL16_HUMAN
NC score	0.016454 (rank : 27)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	37	Target Neighborhood Hits	207	Shared Neighborhood Hits	5
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

TAU_MOUSE
NC score	0.015739 (rank : 28)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	37	Target Neighborhood Hits	502	Shared Neighborhood Hits	11
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

GCSP_HUMAN
NC score	0.014739 (rank : 29)	θ value	8.99809 (rank : 33)
Query Neighborhood Hits	37	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	P23378	Gene names	GLDC, GCSP
Domain Architecture
Description	Glycine dehydrogenase [decarboxylating], mitochondrial precursor (EC 1.4.4.2) (Glycine decarboxylase) (Glycine cleavage system P- protein).

ZFY16_MOUSE
NC score	0.014598 (rank : 30)	θ value	5.27518 (rank : 25)
Query Neighborhood Hits	37	Target Neighborhood Hits	108	Shared Neighborhood Hits	3
SwissProt Accessions	Q80U44, Q8BRD2, Q8CG97	Gene names	Zfyve16, Kiaa0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosomal- associated FYVE domain protein).

RHG25_MOUSE
NC score	0.010138 (rank : 31)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	37	Target Neighborhood Hits	492	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

ANK2_HUMAN
NC score	0.009893 (rank : 32)	θ value	8.99809 (rank : 31)
Query Neighborhood Hits	37	Target Neighborhood Hits	1615	Shared Neighborhood Hits	19
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

CEND3_HUMAN
NC score	0.008426 (rank : 33)	θ value	8.99809 (rank : 32)
Query Neighborhood Hits	37	Target Neighborhood Hits	275	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

PGCB_MOUSE
NC score	0.008157 (rank : 34)	θ value	5.27518 (rank : 20)
Query Neighborhood Hits	37	Target Neighborhood Hits	459	Shared Neighborhood Hits	3
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

HCN3_MOUSE
NC score	0.008009 (rank : 35)	θ value	6.88961 (rank : 27)
Query Neighborhood Hits	37	Target Neighborhood Hits	112	Shared Neighborhood Hits	3
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

STK10_HUMAN
NC score	0.004236 (rank : 36)	θ value	6.88961 (rank : 29)
Query Neighborhood Hits	37	Target Neighborhood Hits	1921	Shared Neighborhood Hits	11
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

MRCKG_MOUSE
NC score	0.003341 (rank : 37)	θ value	5.27518 (rank : 19)
Query Neighborhood Hits	37	Target Neighborhood Hits	1466	Shared Neighborhood Hits	8
SwissProt Accessions	Q80UW5	Gene names	Cdc42bpg
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).