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Network neighborhood for query Sequence : MAFF_HUMAN

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MAFF_HUMAN
SwissProt Accessions	Q9ULX9, Q9Y525	Gene names	MAFF
Domain Architecture
Description	Transcription factor MafF (V-maf musculoaponeurotic fibrosarcoma oncogene homolog F) (U-Maf).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MAFF_HUMAN
θ value	5.7252e-63 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	54	Target Neighborhood Hits	54	Shared Neighborhood Hits	54
SwissProt Accessions	Q9ULX9, Q9Y525	Gene names	MAFF
Domain Architecture
Description	Transcription factor MafF (V-maf musculoaponeurotic fibrosarcoma oncogene homolog F) (U-Maf).

MAFF_MOUSE
θ value	1.55911e-60 (rank : 2)	NC score	0.998208 (rank : 2)
Query Neighborhood Hits	54	Target Neighborhood Hits	53	Shared Neighborhood Hits	50
SwissProt Accessions	O54791	Gene names	Maff
Domain Architecture
Description	Transcription factor MafF (V-maf musculoaponeurotic fibrosarcoma oncogene homolog F).

MAFK_HUMAN
θ value	3.05695e-40 (rank : 3)	NC score	0.968750 (rank : 4)
Query Neighborhood Hits	54	Target Neighborhood Hits	73	Shared Neighborhood Hits	34
SwissProt Accessions	O60675	Gene names	MAFK
Domain Architecture
Description	Transcription factor MafK (Erythroid transcription factor NF-E2 p18 subunit).

MAFK_MOUSE
θ value	3.99248e-40 (rank : 4)	NC score	0.968960 (rank : 3)
Query Neighborhood Hits	54	Target Neighborhood Hits	73	Shared Neighborhood Hits	34
SwissProt Accessions	Q61827, Q60600	Gene names	Mafk, Nfe2u
Domain Architecture
Description	Transcription factor MafK (Erythroid transcription factor NF-E2 p18 subunit).

MAFG_MOUSE
θ value	2.96089e-35 (rank : 5)	NC score	0.966694 (rank : 6)
Query Neighborhood Hits	54	Target Neighborhood Hits	90	Shared Neighborhood Hits	39
SwissProt Accessions	O54790	Gene names	Mafg
Domain Architecture
Description	Transcription factor MafG (V-maf musculoaponeurotic fibrosarcoma oncogene homolog G).

MAFG_HUMAN
θ value	3.86705e-35 (rank : 6)	NC score	0.966970 (rank : 5)
Query Neighborhood Hits	54	Target Neighborhood Hits	85	Shared Neighborhood Hits	38
SwissProt Accessions	O15525	Gene names	MAFG
Domain Architecture
Description	Transcription factor MafG (V-maf musculoaponeurotic fibrosarcoma oncogene homolog G) (hMAF).

MAFB_HUMAN
θ value	7.56453e-23 (rank : 7)	NC score	0.877188 (rank : 10)
Query Neighborhood Hits	54	Target Neighborhood Hits	96	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y5Q3, Q9H1F1	Gene names	MAFB, KRML
Domain Architecture
Description	Transcription factor MafB (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B).

MAFB_MOUSE
θ value	7.56453e-23 (rank : 8)	NC score	0.877364 (rank : 9)
Query Neighborhood Hits	54	Target Neighborhood Hits	92	Shared Neighborhood Hits	28
SwissProt Accessions	P54841	Gene names	Mafb, Krml, Maf1
Domain Architecture
Description	Transcription factor MafB (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B) (Transcription factor MAF1) (Segmentation protein KR) (Kreisler).

MAF_HUMAN
θ value	3.17815e-21 (rank : 9)	NC score	0.892577 (rank : 8)
Query Neighborhood Hits	54	Target Neighborhood Hits	97	Shared Neighborhood Hits	23
SwissProt Accessions	O75444, Q9UP93	Gene names	MAF
Domain Architecture
Description	Transcription factor Maf (Proto-oncogene c-maf).

MAF_MOUSE
θ value	3.17815e-21 (rank : 10)	NC score	0.899630 (rank : 7)
Query Neighborhood Hits	54	Target Neighborhood Hits	95	Shared Neighborhood Hits	24
SwissProt Accessions	P54843	Gene names	Maf, Maf2
Domain Architecture
Description	Transcription factor Maf (Proto-oncogene c-maf).

NRL_HUMAN
θ value	2.88119e-14 (rank : 11)	NC score	0.826911 (rank : 12)
Query Neighborhood Hits	54	Target Neighborhood Hits	39	Shared Neighborhood Hits	23
SwissProt Accessions	P54845	Gene names	NRL
Domain Architecture
Description	Neural retina-specific leucine zipper protein (NRL) (D14S46E).

NRL_MOUSE
θ value	2.88119e-14 (rank : 12)	NC score	0.829718 (rank : 11)
Query Neighborhood Hits	54	Target Neighborhood Hits	36	Shared Neighborhood Hits	24
SwissProt Accessions	P54846	Gene names	Nrl
Domain Architecture
Description	Neural retina-specific leucine zipper protein (NRL).

NF2L1_HUMAN
θ value	0.0252991 (rank : 13)	NC score	0.204649 (rank : 13)
Query Neighborhood Hits	54	Target Neighborhood Hits	169	Shared Neighborhood Hits	27
SwissProt Accessions	Q14494, Q12877, Q96FN6	Gene names	NFE2L1, HBZ17, NRF1, TCF11
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1) (Transcription factor 11) (Transcription factor HBZ17) (Transcription factor LCR-F1) (Locus control region-factor 1).

NF2L1_MOUSE
θ value	0.0252991 (rank : 14)	NC score	0.201021 (rank : 14)
Query Neighborhood Hits	54	Target Neighborhood Hits	185	Shared Neighborhood Hits	28
SwissProt Accessions	Q61985, O70234	Gene names	Nfe2l1, Nrf1
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1).

MYH11_HUMAN
θ value	0.163984 (rank : 15)	NC score	0.040900 (rank : 42)
Query Neighborhood Hits	54	Target Neighborhood Hits	1806	Shared Neighborhood Hits	35
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH11_MOUSE
θ value	0.163984 (rank : 16)	NC score	0.041127 (rank : 40)
Query Neighborhood Hits	54	Target Neighborhood Hits	1777	Shared Neighborhood Hits	35
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

GOGA2_MOUSE
θ value	0.365318 (rank : 17)	NC score	0.047347 (rank : 37)
Query Neighborhood Hits	54	Target Neighborhood Hits	944	Shared Neighborhood Hits	27
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

SMC2_MOUSE
θ value	0.813845 (rank : 18)	NC score	0.033000 (rank : 46)
Query Neighborhood Hits	54	Target Neighborhood Hits	1131	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

ATF6A_HUMAN
θ value	1.06291 (rank : 19)	NC score	0.158176 (rank : 15)
Query Neighborhood Hits	54	Target Neighborhood Hits	174	Shared Neighborhood Hits	30
SwissProt Accessions	P18850, O15139, Q5VW62, Q6IPB5, Q9UEC9	Gene names	ATF6
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 alpha (Activating transcription factor 6 alpha) (ATF6-alpha).

NUF2_MOUSE
θ value	1.06291 (rank : 20)	NC score	0.041139 (rank : 39)
Query Neighborhood Hits	54	Target Neighborhood Hits	585	Shared Neighborhood Hits	21
SwissProt Accessions	Q99P69, Q8BTK7, Q8VE05, Q9CST5	Gene names	Cdca1, Nuf2r
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (Cell division cycle-associated protein 1).

CENPE_HUMAN
θ value	1.38821 (rank : 21)	NC score	0.025616 (rank : 51)
Query Neighborhood Hits	54	Target Neighborhood Hits	2060	Shared Neighborhood Hits	29
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

NEMO_HUMAN
θ value	1.81305 (rank : 22)	NC score	0.031416 (rank : 48)
Query Neighborhood Hits	54	Target Neighborhood Hits	820	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

NF2L2_MOUSE
θ value	1.81305 (rank : 23)	NC score	0.142257 (rank : 17)
Query Neighborhood Hits	54	Target Neighborhood Hits	183	Shared Neighborhood Hits	25
SwissProt Accessions	Q60795	Gene names	Nfe2l2, Nrf-2, Nrf2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2).

RUFY1_MOUSE
θ value	1.81305 (rank : 24)	NC score	0.025232 (rank : 52)
Query Neighborhood Hits	54	Target Neighborhood Hits	765	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

GRAP1_MOUSE
θ value	2.36792 (rank : 25)	NC score	0.022932 (rank : 54)
Query Neighborhood Hits	54	Target Neighborhood Hits	1234	Shared Neighborhood Hits	21
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

MYH9_MOUSE
θ value	2.36792 (rank : 26)	NC score	0.035050 (rank : 45)
Query Neighborhood Hits	54	Target Neighborhood Hits	1829	Shared Neighborhood Hits	32
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

OPTN_MOUSE
θ value	2.36792 (rank : 27)	NC score	0.043063 (rank : 38)
Query Neighborhood Hits	54	Target Neighborhood Hits	1120	Shared Neighborhood Hits	29
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

JUND_HUMAN
θ value	3.0926 (rank : 28)	NC score	0.142033 (rank : 18)
Query Neighborhood Hits	54	Target Neighborhood Hits	122	Shared Neighborhood Hits	29
SwissProt Accessions	P17535	Gene names	JUND
Domain Architecture
Description	Transcription factor jun-D.

JUND_MOUSE
θ value	3.0926 (rank : 29)	NC score	0.140345 (rank : 19)
Query Neighborhood Hits	54	Target Neighborhood Hits	134	Shared Neighborhood Hits	29
SwissProt Accessions	P15066	Gene names	Jund, Jun-d, Jund1
Domain Architecture
Description	Transcription factor jun-D.

NUMA1_HUMAN
θ value	3.0926 (rank : 30)	NC score	0.032852 (rank : 47)
Query Neighborhood Hits	54	Target Neighborhood Hits	1523	Shared Neighborhood Hits	30
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

BACH2_HUMAN
θ value	4.03905 (rank : 31)	NC score	0.054030 (rank : 34)
Query Neighborhood Hits	54	Target Neighborhood Hits	234	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BYV9, Q59H70, Q5T793, Q9NTS5	Gene names	BACH2
Domain Architecture
Description	Transcription regulator protein BACH2 (BTB and CNC homolog 2).

CP250_MOUSE
θ value	4.03905 (rank : 32)	NC score	0.038159 (rank : 44)
Query Neighborhood Hits	54	Target Neighborhood Hits	1583	Shared Neighborhood Hits	30
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

GOGA3_MOUSE
θ value	4.03905 (rank : 33)	NC score	0.027990 (rank : 50)
Query Neighborhood Hits	54	Target Neighborhood Hits	1437	Shared Neighborhood Hits	25
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

JUNB_HUMAN
θ value	4.03905 (rank : 34)	NC score	0.114687 (rank : 23)
Query Neighborhood Hits	54	Target Neighborhood Hits	97	Shared Neighborhood Hits	27
SwissProt Accessions	P17275, Q96GH3	Gene names	JUNB
Domain Architecture
Description	Transcription factor jun-B.

JUNB_MOUSE
θ value	4.03905 (rank : 35)	NC score	0.112740 (rank : 24)
Query Neighborhood Hits	54	Target Neighborhood Hits	116	Shared Neighborhood Hits	27
SwissProt Accessions	P09450, Q8C2G9	Gene names	Junb, Jun-b
Domain Architecture
Description	Transcription factor jun-B.

JUN_HUMAN
θ value	4.03905 (rank : 36)	NC score	0.125826 (rank : 22)
Query Neighborhood Hits	54	Target Neighborhood Hits	144	Shared Neighborhood Hits	31
SwissProt Accessions	P05412, Q96G93	Gene names	JUN
Domain Architecture
Description	Transcription factor AP-1 (Activator protein 1) (AP1) (Proto-oncogene c-jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39).

JUN_MOUSE
θ value	4.03905 (rank : 37)	NC score	0.125920 (rank : 21)
Query Neighborhood Hits	54	Target Neighborhood Hits	145	Shared Neighborhood Hits	31
SwissProt Accessions	P05627	Gene names	Jun
Domain Architecture
Description	Transcription factor AP-1 (Activator protein 1) (AP1) (Proto-oncogene c-jun) (V-jun avian sarcoma virus 17 oncogene homolog) (Jun A) (AH119).

LRSM1_HUMAN
θ value	4.03905 (rank : 38)	NC score	0.015183 (rank : 56)
Query Neighborhood Hits	54	Target Neighborhood Hits	1078	Shared Neighborhood Hits	20
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

ATF7_HUMAN
θ value	5.27518 (rank : 39)	NC score	0.061636 (rank : 29)
Query Neighborhood Hits	54	Target Neighborhood Hits	333	Shared Neighborhood Hits	23
SwissProt Accessions	P17544, Q13814	Gene names	ATF7, ATFA
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

ATF7_MOUSE
θ value	5.27518 (rank : 40)	NC score	0.063799 (rank : 28)
Query Neighborhood Hits	54	Target Neighborhood Hits	286	Shared Neighborhood Hits	23
SwissProt Accessions	Q8R0S1	Gene names	Atf7
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

GAS8_MOUSE
θ value	5.27518 (rank : 41)	NC score	0.028928 (rank : 49)
Query Neighborhood Hits	54	Target Neighborhood Hits	622	Shared Neighborhood Hits	22
SwissProt Accessions	Q60779, Q99L71	Gene names	Gas8, Gas11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

REST_MOUSE
θ value	5.27518 (rank : 42)	NC score	0.021996 (rank : 55)
Query Neighborhood Hits	54	Target Neighborhood Hits	1506	Shared Neighborhood Hits	23
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

ATF2_HUMAN
θ value	6.88961 (rank : 43)	NC score	0.048711 (rank : 36)
Query Neighborhood Hits	54	Target Neighborhood Hits	402	Shared Neighborhood Hits	21
SwissProt Accessions	P15336, Q13000	Gene names	ATF2, CREB2, CREBP1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (HB16).

ATF2_MOUSE
θ value	6.88961 (rank : 44)	NC score	0.048788 (rank : 35)
Query Neighborhood Hits	54	Target Neighborhood Hits	397	Shared Neighborhood Hits	22
SwissProt Accessions	P16951, Q64089, Q64090, Q64091	Gene names	Atf2
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (MXBP protein).

ATF6B_MOUSE
θ value	6.88961 (rank : 45)	NC score	0.041096 (rank : 41)
Query Neighborhood Hits	54	Target Neighborhood Hits	97	Shared Neighborhood Hits	13
SwissProt Accessions	O35451	Gene names	Crebl1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp).

DDIT3_HUMAN
θ value	6.88961 (rank : 46)	NC score	0.024543 (rank : 53)
Query Neighborhood Hits	54	Target Neighborhood Hits	167	Shared Neighborhood Hits	8
SwissProt Accessions	P35638	Gene names	DDIT3, CHOP, GADD153
Domain Architecture
Description	DNA damage-inducible transcript 3 (DDIT-3) (Growth arrest and DNA- damage-inducible protein GADD153) (C/EBP-homologous protein) (CHOP).

GABP2_HUMAN
θ value	6.88961 (rank : 47)	NC score	0.006890 (rank : 62)
Query Neighborhood Hits	54	Target Neighborhood Hits	454	Shared Neighborhood Hits	11
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

KIF12_HUMAN
θ value	6.88961 (rank : 48)	NC score	0.009534 (rank : 61)
Query Neighborhood Hits	54	Target Neighborhood Hits	148	Shared Neighborhood Hits	9
SwissProt Accessions	Q96FN5, Q5TBE0	Gene names	KIF12
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF12.

MRCKA_HUMAN
θ value	6.88961 (rank : 49)	NC score	0.014517 (rank : 57)
Query Neighborhood Hits	54	Target Neighborhood Hits	1999	Shared Neighborhood Hits	29
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

TAK1L_HUMAN
θ value	6.88961 (rank : 50)	NC score	0.076094 (rank : 27)
Query Neighborhood Hits	54	Target Neighborhood Hits	141	Shared Neighborhood Hits	14
SwissProt Accessions	P57077	Gene names	TAK1L, C21orf7
Domain Architecture	No domain graphic available
Description	TAK1-like protein.

ATF6B_HUMAN
θ value	8.99809 (rank : 51)	NC score	0.039279 (rank : 43)
Query Neighborhood Hits	54	Target Neighborhood Hits	122	Shared Neighborhood Hits	13
SwissProt Accessions	Q99941, Q13269, Q14343, Q14345, Q99635, Q99637, Q9H3V9, Q9H3W1, Q9NPL0	Gene names	CREBL1, G13
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp) (Protein G13).

MICA1_MOUSE
θ value	8.99809 (rank : 52)	NC score	0.013975 (rank : 58)
Query Neighborhood Hits	54	Target Neighborhood Hits	400	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VDP3	Gene names	Mical1, Mical, Nical
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

SETD8_HUMAN
θ value	8.99809 (rank : 53)	NC score	0.012774 (rank : 59)
Query Neighborhood Hits	54	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).

SNIP_MOUSE
θ value	8.99809 (rank : 54)	NC score	0.010906 (rank : 60)
Query Neighborhood Hits	54	Target Neighborhood Hits	319	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QWI6, O70298	Gene names	P140, Kiaa1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

ATF3_HUMAN
θ value	θ > 10 (rank : 55)	NC score	0.057975 (rank : 30)
Query Neighborhood Hits	54	Target Neighborhood Hits	120	Shared Neighborhood Hits	26
SwissProt Accessions	P18847	Gene names	ATF3
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-3 (Activating transcription factor 3).

BACH1_HUMAN
θ value	θ > 10 (rank : 56)	NC score	0.055767 (rank : 32)
Query Neighborhood Hits	54	Target Neighborhood Hits	289	Shared Neighborhood Hits	30
SwissProt Accessions	O14867, O43285	Gene names	BACH1
Domain Architecture
Description	Transcription regulator protein BACH1 (BTB and CNC homolog 1) (HA2303).

BACH1_MOUSE
θ value	θ > 10 (rank : 57)	NC score	0.057493 (rank : 31)
Query Neighborhood Hits	54	Target Neighborhood Hits	289	Shared Neighborhood Hits	27
SwissProt Accessions	P97302	Gene names	Bach1
Domain Architecture
Description	Transcription regulator protein BACH1 (BTB and CNC homolog 1).

CREB5_HUMAN
θ value	θ > 10 (rank : 58)	NC score	0.054427 (rank : 33)
Query Neighborhood Hits	54	Target Neighborhood Hits	222	Shared Neighborhood Hits	20
SwissProt Accessions	Q02930, Q05886, Q06246	Gene names	CREB5, CREBPA
Domain Architecture
Description	cAMP response element-binding protein 5 (CRE-BPa).

NF2L2_HUMAN
θ value	θ > 10 (rank : 59)	NC score	0.081906 (rank : 26)
Query Neighborhood Hits	54	Target Neighborhood Hits	109	Shared Neighborhood Hits	15
SwissProt Accessions	Q16236, Q96F71	Gene names	NFE2L2, NRF2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2) (HEBP1).

NF2L3_HUMAN
θ value	θ > 10 (rank : 60)	NC score	0.134262 (rank : 20)
Query Neighborhood Hits	54	Target Neighborhood Hits	150	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y4A8, Q6NUS0, Q7Z498, Q86UJ4, Q86VR5, Q9UQA4	Gene names	NFE2L3, NRF3
Domain Architecture	No domain graphic available
Description	Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3).

NF2L3_MOUSE
θ value	θ > 10 (rank : 61)	NC score	0.153433 (rank : 16)
Query Neighborhood Hits	54	Target Neighborhood Hits	93	Shared Neighborhood Hits	21
SwissProt Accessions	Q9WTM4	Gene names	Nfe2l3, Nrf3
Domain Architecture	No domain graphic available
Description	Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3).

NFE2_HUMAN
θ value	θ > 10 (rank : 62)	NC score	0.107802 (rank : 25)
Query Neighborhood Hits	54	Target Neighborhood Hits	66	Shared Neighborhood Hits	15
SwissProt Accessions	Q16621, Q07720, Q6ICV9	Gene names	NFE2
Domain Architecture	No domain graphic available
Description	Transcription factor NF-E2 45 kDa subunit (Nuclear factor, erythroid- derived 2 45 kDa subunit) (p45 NF-E2) (Leucine zipper protein NF-E2).

Hits sorted by NC score

MAFF_HUMAN
NC score	0.999962 (rank : 1)	θ value	5.7252e-63 (rank : 1)
Query Neighborhood Hits	54	Target Neighborhood Hits	54	Shared Neighborhood Hits	54
SwissProt Accessions	Q9ULX9, Q9Y525	Gene names	MAFF
Domain Architecture
Description	Transcription factor MafF (V-maf musculoaponeurotic fibrosarcoma oncogene homolog F) (U-Maf).

MAFF_MOUSE
NC score	0.998208 (rank : 2)	θ value	1.55911e-60 (rank : 2)
Query Neighborhood Hits	54	Target Neighborhood Hits	53	Shared Neighborhood Hits	50
SwissProt Accessions	O54791	Gene names	Maff
Domain Architecture
Description	Transcription factor MafF (V-maf musculoaponeurotic fibrosarcoma oncogene homolog F).

MAFK_MOUSE
NC score	0.968960 (rank : 3)	θ value	3.99248e-40 (rank : 4)
Query Neighborhood Hits	54	Target Neighborhood Hits	73	Shared Neighborhood Hits	34
SwissProt Accessions	Q61827, Q60600	Gene names	Mafk, Nfe2u
Domain Architecture
Description	Transcription factor MafK (Erythroid transcription factor NF-E2 p18 subunit).

MAFK_HUMAN
NC score	0.968750 (rank : 4)	θ value	3.05695e-40 (rank : 3)
Query Neighborhood Hits	54	Target Neighborhood Hits	73	Shared Neighborhood Hits	34
SwissProt Accessions	O60675	Gene names	MAFK
Domain Architecture
Description	Transcription factor MafK (Erythroid transcription factor NF-E2 p18 subunit).

MAFG_HUMAN
NC score	0.966970 (rank : 5)	θ value	3.86705e-35 (rank : 6)
Query Neighborhood Hits	54	Target Neighborhood Hits	85	Shared Neighborhood Hits	38
SwissProt Accessions	O15525	Gene names	MAFG
Domain Architecture
Description	Transcription factor MafG (V-maf musculoaponeurotic fibrosarcoma oncogene homolog G) (hMAF).

MAFG_MOUSE
NC score	0.966694 (rank : 6)	θ value	2.96089e-35 (rank : 5)
Query Neighborhood Hits	54	Target Neighborhood Hits	90	Shared Neighborhood Hits	39
SwissProt Accessions	O54790	Gene names	Mafg
Domain Architecture
Description	Transcription factor MafG (V-maf musculoaponeurotic fibrosarcoma oncogene homolog G).

MAF_MOUSE
NC score	0.899630 (rank : 7)	θ value	3.17815e-21 (rank : 10)
Query Neighborhood Hits	54	Target Neighborhood Hits	95	Shared Neighborhood Hits	24
SwissProt Accessions	P54843	Gene names	Maf, Maf2
Domain Architecture
Description	Transcription factor Maf (Proto-oncogene c-maf).

MAF_HUMAN
NC score	0.892577 (rank : 8)	θ value	3.17815e-21 (rank : 9)
Query Neighborhood Hits	54	Target Neighborhood Hits	97	Shared Neighborhood Hits	23
SwissProt Accessions	O75444, Q9UP93	Gene names	MAF
Domain Architecture
Description	Transcription factor Maf (Proto-oncogene c-maf).

MAFB_MOUSE
NC score	0.877364 (rank : 9)	θ value	7.56453e-23 (rank : 8)
Query Neighborhood Hits	54	Target Neighborhood Hits	92	Shared Neighborhood Hits	28
SwissProt Accessions	P54841	Gene names	Mafb, Krml, Maf1
Domain Architecture
Description	Transcription factor MafB (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B) (Transcription factor MAF1) (Segmentation protein KR) (Kreisler).

MAFB_HUMAN
NC score	0.877188 (rank : 10)	θ value	7.56453e-23 (rank : 7)
Query Neighborhood Hits	54	Target Neighborhood Hits	96	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y5Q3, Q9H1F1	Gene names	MAFB, KRML
Domain Architecture
Description	Transcription factor MafB (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B).

NRL_MOUSE
NC score	0.829718 (rank : 11)	θ value	2.88119e-14 (rank : 12)
Query Neighborhood Hits	54	Target Neighborhood Hits	36	Shared Neighborhood Hits	24
SwissProt Accessions	P54846	Gene names	Nrl
Domain Architecture
Description	Neural retina-specific leucine zipper protein (NRL).

NRL_HUMAN
NC score	0.826911 (rank : 12)	θ value	2.88119e-14 (rank : 11)
Query Neighborhood Hits	54	Target Neighborhood Hits	39	Shared Neighborhood Hits	23
SwissProt Accessions	P54845	Gene names	NRL
Domain Architecture
Description	Neural retina-specific leucine zipper protein (NRL) (D14S46E).

NF2L1_HUMAN
NC score	0.204649 (rank : 13)	θ value	0.0252991 (rank : 13)
Query Neighborhood Hits	54	Target Neighborhood Hits	169	Shared Neighborhood Hits	27
SwissProt Accessions	Q14494, Q12877, Q96FN6	Gene names	NFE2L1, HBZ17, NRF1, TCF11
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1) (Transcription factor 11) (Transcription factor HBZ17) (Transcription factor LCR-F1) (Locus control region-factor 1).

NF2L1_MOUSE
NC score	0.201021 (rank : 14)	θ value	0.0252991 (rank : 14)
Query Neighborhood Hits	54	Target Neighborhood Hits	185	Shared Neighborhood Hits	28
SwissProt Accessions	Q61985, O70234	Gene names	Nfe2l1, Nrf1
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1).

ATF6A_HUMAN
NC score	0.158176 (rank : 15)	θ value	1.06291 (rank : 19)
Query Neighborhood Hits	54	Target Neighborhood Hits	174	Shared Neighborhood Hits	30
SwissProt Accessions	P18850, O15139, Q5VW62, Q6IPB5, Q9UEC9	Gene names	ATF6
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 alpha (Activating transcription factor 6 alpha) (ATF6-alpha).

NF2L3_MOUSE
NC score	0.153433 (rank : 16)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	54	Target Neighborhood Hits	93	Shared Neighborhood Hits	21
SwissProt Accessions	Q9WTM4	Gene names	Nfe2l3, Nrf3
Domain Architecture	No domain graphic available
Description	Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3).

NF2L2_MOUSE
NC score	0.142257 (rank : 17)	θ value	1.81305 (rank : 23)
Query Neighborhood Hits	54	Target Neighborhood Hits	183	Shared Neighborhood Hits	25
SwissProt Accessions	Q60795	Gene names	Nfe2l2, Nrf-2, Nrf2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2).

JUND_HUMAN
NC score	0.142033 (rank : 18)	θ value	3.0926 (rank : 28)
Query Neighborhood Hits	54	Target Neighborhood Hits	122	Shared Neighborhood Hits	29
SwissProt Accessions	P17535	Gene names	JUND
Domain Architecture
Description	Transcription factor jun-D.

JUND_MOUSE
NC score	0.140345 (rank : 19)	θ value	3.0926 (rank : 29)
Query Neighborhood Hits	54	Target Neighborhood Hits	134	Shared Neighborhood Hits	29
SwissProt Accessions	P15066	Gene names	Jund, Jun-d, Jund1
Domain Architecture
Description	Transcription factor jun-D.

NF2L3_HUMAN
NC score	0.134262 (rank : 20)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	54	Target Neighborhood Hits	150	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y4A8, Q6NUS0, Q7Z498, Q86UJ4, Q86VR5, Q9UQA4	Gene names	NFE2L3, NRF3
Domain Architecture	No domain graphic available
Description	Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3).

JUN_MOUSE
NC score	0.125920 (rank : 21)	θ value	4.03905 (rank : 37)
Query Neighborhood Hits	54	Target Neighborhood Hits	145	Shared Neighborhood Hits	31
SwissProt Accessions	P05627	Gene names	Jun
Domain Architecture
Description	Transcription factor AP-1 (Activator protein 1) (AP1) (Proto-oncogene c-jun) (V-jun avian sarcoma virus 17 oncogene homolog) (Jun A) (AH119).

JUN_HUMAN
NC score	0.125826 (rank : 22)	θ value	4.03905 (rank : 36)
Query Neighborhood Hits	54	Target Neighborhood Hits	144	Shared Neighborhood Hits	31
SwissProt Accessions	P05412, Q96G93	Gene names	JUN
Domain Architecture
Description	Transcription factor AP-1 (Activator protein 1) (AP1) (Proto-oncogene c-jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39).

JUNB_HUMAN
NC score	0.114687 (rank : 23)	θ value	4.03905 (rank : 34)
Query Neighborhood Hits	54	Target Neighborhood Hits	97	Shared Neighborhood Hits	27
SwissProt Accessions	P17275, Q96GH3	Gene names	JUNB
Domain Architecture
Description	Transcription factor jun-B.

JUNB_MOUSE
NC score	0.112740 (rank : 24)	θ value	4.03905 (rank : 35)
Query Neighborhood Hits	54	Target Neighborhood Hits	116	Shared Neighborhood Hits	27
SwissProt Accessions	P09450, Q8C2G9	Gene names	Junb, Jun-b
Domain Architecture
Description	Transcription factor jun-B.

NFE2_HUMAN
NC score	0.107802 (rank : 25)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	54	Target Neighborhood Hits	66	Shared Neighborhood Hits	15
SwissProt Accessions	Q16621, Q07720, Q6ICV9	Gene names	NFE2
Domain Architecture	No domain graphic available
Description	Transcription factor NF-E2 45 kDa subunit (Nuclear factor, erythroid- derived 2 45 kDa subunit) (p45 NF-E2) (Leucine zipper protein NF-E2).

NF2L2_HUMAN
NC score	0.081906 (rank : 26)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	54	Target Neighborhood Hits	109	Shared Neighborhood Hits	15
SwissProt Accessions	Q16236, Q96F71	Gene names	NFE2L2, NRF2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2) (HEBP1).

TAK1L_HUMAN
NC score	0.076094 (rank : 27)	θ value	6.88961 (rank : 50)
Query Neighborhood Hits	54	Target Neighborhood Hits	141	Shared Neighborhood Hits	14
SwissProt Accessions	P57077	Gene names	TAK1L, C21orf7
Domain Architecture	No domain graphic available
Description	TAK1-like protein.

ATF7_MOUSE
NC score	0.063799 (rank : 28)	θ value	5.27518 (rank : 40)
Query Neighborhood Hits	54	Target Neighborhood Hits	286	Shared Neighborhood Hits	23
SwissProt Accessions	Q8R0S1	Gene names	Atf7
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

ATF7_HUMAN
NC score	0.061636 (rank : 29)	θ value	5.27518 (rank : 39)
Query Neighborhood Hits	54	Target Neighborhood Hits	333	Shared Neighborhood Hits	23
SwissProt Accessions	P17544, Q13814	Gene names	ATF7, ATFA
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

ATF3_HUMAN
NC score	0.057975 (rank : 30)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	54	Target Neighborhood Hits	120	Shared Neighborhood Hits	26
SwissProt Accessions	P18847	Gene names	ATF3
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-3 (Activating transcription factor 3).

BACH1_MOUSE
NC score	0.057493 (rank : 31)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	54	Target Neighborhood Hits	289	Shared Neighborhood Hits	27
SwissProt Accessions	P97302	Gene names	Bach1
Domain Architecture
Description	Transcription regulator protein BACH1 (BTB and CNC homolog 1).

BACH1_HUMAN
NC score	0.055767 (rank : 32)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	54	Target Neighborhood Hits	289	Shared Neighborhood Hits	30
SwissProt Accessions	O14867, O43285	Gene names	BACH1
Domain Architecture
Description	Transcription regulator protein BACH1 (BTB and CNC homolog 1) (HA2303).

CREB5_HUMAN
NC score	0.054427 (rank : 33)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	54	Target Neighborhood Hits	222	Shared Neighborhood Hits	20
SwissProt Accessions	Q02930, Q05886, Q06246	Gene names	CREB5, CREBPA
Domain Architecture
Description	cAMP response element-binding protein 5 (CRE-BPa).

BACH2_HUMAN
NC score	0.054030 (rank : 34)	θ value	4.03905 (rank : 31)
Query Neighborhood Hits	54	Target Neighborhood Hits	234	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BYV9, Q59H70, Q5T793, Q9NTS5	Gene names	BACH2
Domain Architecture
Description	Transcription regulator protein BACH2 (BTB and CNC homolog 2).

ATF2_MOUSE
NC score	0.048788 (rank : 35)	θ value	6.88961 (rank : 44)
Query Neighborhood Hits	54	Target Neighborhood Hits	397	Shared Neighborhood Hits	22
SwissProt Accessions	P16951, Q64089, Q64090, Q64091	Gene names	Atf2
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (MXBP protein).

ATF2_HUMAN
NC score	0.048711 (rank : 36)	θ value	6.88961 (rank : 43)
Query Neighborhood Hits	54	Target Neighborhood Hits	402	Shared Neighborhood Hits	21
SwissProt Accessions	P15336, Q13000	Gene names	ATF2, CREB2, CREBP1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (HB16).

GOGA2_MOUSE
NC score	0.047347 (rank : 37)	θ value	0.365318 (rank : 17)
Query Neighborhood Hits	54	Target Neighborhood Hits	944	Shared Neighborhood Hits	27
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

OPTN_MOUSE
NC score	0.043063 (rank : 38)	θ value	2.36792 (rank : 27)
Query Neighborhood Hits	54	Target Neighborhood Hits	1120	Shared Neighborhood Hits	29
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

NUF2_MOUSE
NC score	0.041139 (rank : 39)	θ value	1.06291 (rank : 20)
Query Neighborhood Hits	54	Target Neighborhood Hits	585	Shared Neighborhood Hits	21
SwissProt Accessions	Q99P69, Q8BTK7, Q8VE05, Q9CST5	Gene names	Cdca1, Nuf2r
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (Cell division cycle-associated protein 1).

MYH11_MOUSE
NC score	0.041127 (rank : 40)	θ value	0.163984 (rank : 16)
Query Neighborhood Hits	54	Target Neighborhood Hits	1777	Shared Neighborhood Hits	35
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

ATF6B_MOUSE
NC score	0.041096 (rank : 41)	θ value	6.88961 (rank : 45)
Query Neighborhood Hits	54	Target Neighborhood Hits	97	Shared Neighborhood Hits	13
SwissProt Accessions	O35451	Gene names	Crebl1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp).

MYH11_HUMAN
NC score	0.040900 (rank : 42)	θ value	0.163984 (rank : 15)
Query Neighborhood Hits	54	Target Neighborhood Hits	1806	Shared Neighborhood Hits	35
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

ATF6B_HUMAN
NC score	0.039279 (rank : 43)	θ value	8.99809 (rank : 51)
Query Neighborhood Hits	54	Target Neighborhood Hits	122	Shared Neighborhood Hits	13
SwissProt Accessions	Q99941, Q13269, Q14343, Q14345, Q99635, Q99637, Q9H3V9, Q9H3W1, Q9NPL0	Gene names	CREBL1, G13
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp) (Protein G13).

CP250_MOUSE
NC score	0.038159 (rank : 44)	θ value	4.03905 (rank : 32)
Query Neighborhood Hits	54	Target Neighborhood Hits	1583	Shared Neighborhood Hits	30
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

MYH9_MOUSE
NC score	0.035050 (rank : 45)	θ value	2.36792 (rank : 26)
Query Neighborhood Hits	54	Target Neighborhood Hits	1829	Shared Neighborhood Hits	32
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

SMC2_MOUSE
NC score	0.033000 (rank : 46)	θ value	0.813845 (rank : 18)
Query Neighborhood Hits	54	Target Neighborhood Hits	1131	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

NUMA1_HUMAN
NC score	0.032852 (rank : 47)	θ value	3.0926 (rank : 30)
Query Neighborhood Hits	54	Target Neighborhood Hits	1523	Shared Neighborhood Hits	30
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

NEMO_HUMAN
NC score	0.031416 (rank : 48)	θ value	1.81305 (rank : 22)
Query Neighborhood Hits	54	Target Neighborhood Hits	820	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

GAS8_MOUSE
NC score	0.028928 (rank : 49)	θ value	5.27518 (rank : 41)
Query Neighborhood Hits	54	Target Neighborhood Hits	622	Shared Neighborhood Hits	22
SwissProt Accessions	Q60779, Q99L71	Gene names	Gas8, Gas11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

GOGA3_MOUSE
NC score	0.027990 (rank : 50)	θ value	4.03905 (rank : 33)
Query Neighborhood Hits	54	Target Neighborhood Hits	1437	Shared Neighborhood Hits	25
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

CENPE_HUMAN
NC score	0.025616 (rank : 51)	θ value	1.38821 (rank : 21)
Query Neighborhood Hits	54	Target Neighborhood Hits	2060	Shared Neighborhood Hits	29
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

RUFY1_MOUSE
NC score	0.025232 (rank : 52)	θ value	1.81305 (rank : 24)
Query Neighborhood Hits	54	Target Neighborhood Hits	765	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

DDIT3_HUMAN
NC score	0.024543 (rank : 53)	θ value	6.88961 (rank : 46)
Query Neighborhood Hits	54	Target Neighborhood Hits	167	Shared Neighborhood Hits	8
SwissProt Accessions	P35638	Gene names	DDIT3, CHOP, GADD153
Domain Architecture
Description	DNA damage-inducible transcript 3 (DDIT-3) (Growth arrest and DNA- damage-inducible protein GADD153) (C/EBP-homologous protein) (CHOP).

GRAP1_MOUSE
NC score	0.022932 (rank : 54)	θ value	2.36792 (rank : 25)
Query Neighborhood Hits	54	Target Neighborhood Hits	1234	Shared Neighborhood Hits	21
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

REST_MOUSE
NC score	0.021996 (rank : 55)	θ value	5.27518 (rank : 42)
Query Neighborhood Hits	54	Target Neighborhood Hits	1506	Shared Neighborhood Hits	23
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

LRSM1_HUMAN
NC score	0.015183 (rank : 56)	θ value	4.03905 (rank : 38)
Query Neighborhood Hits	54	Target Neighborhood Hits	1078	Shared Neighborhood Hits	20
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

MRCKA_HUMAN
NC score	0.014517 (rank : 57)	θ value	6.88961 (rank : 49)
Query Neighborhood Hits	54	Target Neighborhood Hits	1999	Shared Neighborhood Hits	29
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

MICA1_MOUSE
NC score	0.013975 (rank : 58)	θ value	8.99809 (rank : 52)
Query Neighborhood Hits	54	Target Neighborhood Hits	400	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VDP3	Gene names	Mical1, Mical, Nical
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

SETD8_HUMAN
NC score	0.012774 (rank : 59)	θ value	8.99809 (rank : 53)
Query Neighborhood Hits	54	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).

SNIP_MOUSE
NC score	0.010906 (rank : 60)	θ value	8.99809 (rank : 54)
Query Neighborhood Hits	54	Target Neighborhood Hits	319	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QWI6, O70298	Gene names	P140, Kiaa1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

KIF12_HUMAN
NC score	0.009534 (rank : 61)	θ value	6.88961 (rank : 48)
Query Neighborhood Hits	54	Target Neighborhood Hits	148	Shared Neighborhood Hits	9
SwissProt Accessions	Q96FN5, Q5TBE0	Gene names	KIF12
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF12.

GABP2_HUMAN
NC score	0.006890 (rank : 62)	θ value	6.88961 (rank : 47)
Query Neighborhood Hits	54	Target Neighborhood Hits	454	Shared Neighborhood Hits	11
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).