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Network neighborhood for query Sequence : EPAS1_MOUSE

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EPAS1_MOUSE
SwissProt Accessions	P97481, O08787, O55046	Gene names	Epas1, Hif2a
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Hypoxia- inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (MHLF) (HIF-related factor) (HRF).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

EPAS1_HUMAN
θ value	0 (rank : 1)	NC score	0.994197 (rank : 2)
Query Neighborhood Hits	94	Target Neighborhood Hits	76	Shared Neighborhood Hits	44
SwissProt Accessions	Q99814, Q86VA2, Q99630	Gene names	EPAS1, HIF2A
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Member of PAS protein 2) (MOP2) (Hypoxia-inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (HLF).

EPAS1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	94	Target Neighborhood Hits	94	Shared Neighborhood Hits	94
SwissProt Accessions	P97481, O08787, O55046	Gene names	Epas1, Hif2a
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Hypoxia- inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (MHLF) (HIF-related factor) (HRF).

HIF1A_HUMAN
θ value	2.04462e-161 (rank : 3)	NC score	0.975288 (rank : 4)
Query Neighborhood Hits	94	Target Neighborhood Hits	118	Shared Neighborhood Hits	41
SwissProt Accessions	Q16665, Q96PT9, Q9UPB1	Gene names	HIF1A
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein) (Member of PAS protein 1) (MOP1).

HIF1A_MOUSE
θ value	2.04462e-161 (rank : 4)	NC score	0.977646 (rank : 3)
Query Neighborhood Hits	94	Target Neighborhood Hits	90	Shared Neighborhood Hits	40
SwissProt Accessions	Q61221, O08741, O08993, Q61664, Q61665, Q8C681, Q8CC19, Q8CCB6, Q8R385, Q9CYA8	Gene names	Hif1a
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein).

SIM2_MOUSE
θ value	2.32439e-64 (rank : 5)	NC score	0.923554 (rank : 5)
Query Neighborhood Hits	94	Target Neighborhood Hits	75	Shared Neighborhood Hits	37
SwissProt Accessions	Q61079, O35391, Q61046, Q61904	Gene names	Sim2
Domain Architecture
Description	Single-minded homolog 2 (SIM transcription factor) (mSIM).

SIM1_HUMAN
θ value	3.03575e-64 (rank : 6)	NC score	0.921705 (rank : 7)
Query Neighborhood Hits	94	Target Neighborhood Hits	62	Shared Neighborhood Hits	39
SwissProt Accessions	P81133, Q5TDP7	Gene names	SIM1
Domain Architecture
Description	Single-minded homolog 1.

SIM1_MOUSE
θ value	3.35642e-63 (rank : 7)	NC score	0.920668 (rank : 8)
Query Neighborhood Hits	94	Target Neighborhood Hits	69	Shared Neighborhood Hits	40
SwissProt Accessions	Q61045, O70284, P70183	Gene names	Sim1
Domain Architecture
Description	Single-minded homolog 1 (mSIM1).

SIM2_HUMAN
θ value	4.10295e-61 (rank : 8)	NC score	0.923527 (rank : 6)
Query Neighborhood Hits	94	Target Neighborhood Hits	76	Shared Neighborhood Hits	39
SwissProt Accessions	Q14190, O60766, Q15470, Q15471, Q15472, Q15473, Q16532	Gene names	SIM2
Domain Architecture
Description	Single-minded homolog 2.

NPAS3_HUMAN
θ value	1.36585e-56 (rank : 9)	NC score	0.899765 (rank : 11)
Query Neighborhood Hits	94	Target Neighborhood Hits	81	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IXF0, Q86US6, Q86US7, Q8IXF2, Q9BY81, Q9H323, Q9Y4L8	Gene names	NPAS3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

NPAS3_MOUSE
θ value	1.78386e-56 (rank : 10)	NC score	0.899814 (rank : 10)
Query Neighborhood Hits	94	Target Neighborhood Hits	103	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QZQ0, Q9EQP4	Gene names	Npas3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

NPAS1_MOUSE
θ value	1.23823e-49 (rank : 11)	NC score	0.900850 (rank : 9)
Query Neighborhood Hits	94	Target Neighborhood Hits	63	Shared Neighborhood Hits	32
SwissProt Accessions	P97459	Gene names	Npas1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1).

NPAS1_HUMAN
θ value	6.7944e-48 (rank : 12)	NC score	0.899572 (rank : 12)
Query Neighborhood Hits	94	Target Neighborhood Hits	77	Shared Neighborhood Hits	34
SwissProt Accessions	Q99742, Q99632, Q9BY83	Gene names	NPAS1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1) (Member of PAS protein 5) (MOP5).

ARNT2_MOUSE
θ value	6.82597e-32 (rank : 13)	NC score	0.793341 (rank : 21)
Query Neighborhood Hits	94	Target Neighborhood Hits	115	Shared Neighborhood Hits	38
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT2_HUMAN
θ value	8.91499e-32 (rank : 14)	NC score	0.794139 (rank : 20)
Query Neighborhood Hits	94	Target Neighborhood Hits	109	Shared Neighborhood Hits	38
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

BMAL1_HUMAN
θ value	1.98606e-31 (rank : 15)	NC score	0.829322 (rank : 13)
Query Neighborhood Hits	94	Target Neighborhood Hits	115	Shared Neighborhood Hits	40
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

BMAL1_MOUSE
θ value	3.3877e-31 (rank : 16)	NC score	0.826994 (rank : 14)
Query Neighborhood Hits	94	Target Neighborhood Hits	121	Shared Neighborhood Hits	40
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

ARNT_HUMAN
θ value	2.86786e-30 (rank : 17)	NC score	0.788681 (rank : 23)
Query Neighborhood Hits	94	Target Neighborhood Hits	109	Shared Neighborhood Hits	39
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

NPAS2_MOUSE
θ value	2.86786e-30 (rank : 18)	NC score	0.796372 (rank : 19)
Query Neighborhood Hits	94	Target Neighborhood Hits	132	Shared Neighborhood Hits	41
SwissProt Accessions	P97460	Gene names	Npas2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2).

CLOCK_HUMAN
θ value	4.89182e-30 (rank : 19)	NC score	0.807441 (rank : 17)
Query Neighborhood Hits	94	Target Neighborhood Hits	127	Shared Neighborhood Hits	39
SwissProt Accessions	O15516, O14516, Q9UIT8	Gene names	CLOCK, KIAA0334
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (hCLOCK).

ARNT_MOUSE
θ value	8.3442e-30 (rank : 20)	NC score	0.775106 (rank : 24)
Query Neighborhood Hits	94	Target Neighborhood Hits	213	Shared Neighborhood Hits	40
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

NPAS2_HUMAN
θ value	1.4233e-29 (rank : 21)	NC score	0.789720 (rank : 22)
Query Neighborhood Hits	94	Target Neighborhood Hits	150	Shared Neighborhood Hits	40
SwissProt Accessions	Q99743, Q99629	Gene names	NPAS2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2) (Member of PAS protein 4) (MOP4).

CLOCK_MOUSE
θ value	4.14116e-29 (rank : 22)	NC score	0.803980 (rank : 18)
Query Neighborhood Hits	94	Target Neighborhood Hits	148	Shared Neighborhood Hits	39
SwissProt Accessions	O08785	Gene names	Clock
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (mCLOCK).

AHR_MOUSE
θ value	4.43474e-23 (rank : 23)	NC score	0.812231 (rank : 16)
Query Neighborhood Hits	94	Target Neighborhood Hits	55	Shared Neighborhood Hits	35
SwissProt Accessions	P30561, Q8QZX6, Q8R4S3, Q99P79, Q9QVY1	Gene names	Ahr
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

AHR_HUMAN
θ value	9.87957e-23 (rank : 24)	NC score	0.815426 (rank : 15)
Query Neighborhood Hits	94	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	P35869, Q13728, Q13803, Q13804	Gene names	AHR
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

NPAS4_HUMAN
θ value	1.13037e-18 (rank : 25)	NC score	0.678107 (rank : 25)
Query Neighborhood Hits	94	Target Neighborhood Hits	214	Shared Neighborhood Hits	45
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

NPAS4_MOUSE
θ value	1.24977e-17 (rank : 26)	NC score	0.661451 (rank : 26)
Query Neighborhood Hits	94	Target Neighborhood Hits	245	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

NCOA2_MOUSE
θ value	6.41864e-14 (rank : 27)	NC score	0.567186 (rank : 30)
Query Neighborhood Hits	94	Target Neighborhood Hits	281	Shared Neighborhood Hits	39
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

NCOA2_HUMAN
θ value	1.09485e-13 (rank : 28)	NC score	0.566473 (rank : 31)
Query Neighborhood Hits	94	Target Neighborhood Hits	281	Shared Neighborhood Hits	36
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

NCOA3_HUMAN
θ value	7.84624e-12 (rank : 29)	NC score	0.569862 (rank : 29)
Query Neighborhood Hits	94	Target Neighborhood Hits	171	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7	Gene names	NCOA3, AIB1, RAC3, TRAM1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).

NCOA1_HUMAN
θ value	1.74796e-11 (rank : 30)	NC score	0.617665 (rank : 28)
Query Neighborhood Hits	94	Target Neighborhood Hits	198	Shared Neighborhood Hits	34
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

NCOA1_MOUSE
θ value	3.89403e-11 (rank : 31)	NC score	0.620193 (rank : 27)
Query Neighborhood Hits	94	Target Neighborhood Hits	196	Shared Neighborhood Hits	36
SwissProt Accessions	P70365, P70366, Q61202, Q8CBI9	Gene names	Ncoa1, Src1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (Nuclear receptor coactivator protein 1) (mNRC-1).

NCOA3_MOUSE
θ value	3.29651e-10 (rank : 32)	NC score	0.533502 (rank : 32)
Query Neighborhood Hits	94	Target Neighborhood Hits	203	Shared Neighborhood Hits	36
SwissProt Accessions	O09000, Q9CRD5	Gene names	Ncoa3, Aib1, Pcip, Rac3, Tram1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein homolog) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP- interacting protein) (p/CIP) (pCIP).

PER1_MOUSE
θ value	3.77169e-06 (rank : 33)	NC score	0.325698 (rank : 35)
Query Neighborhood Hits	94	Target Neighborhood Hits	235	Shared Neighborhood Hits	39
SwissProt Accessions	O35973	Gene names	Per1, Per, Rigui
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (mPER) (M-Rigui).

PER3_MOUSE
θ value	6.43352e-06 (rank : 34)	NC score	0.348456 (rank : 33)
Query Neighborhood Hits	94	Target Neighborhood Hits	85	Shared Neighborhood Hits	30
SwissProt Accessions	O70361	Gene names	Per3
Domain Architecture
Description	Period circadian protein 3 (mPER3).

PER1_HUMAN
θ value	8.40245e-06 (rank : 35)	NC score	0.326997 (rank : 34)
Query Neighborhood Hits	94	Target Neighborhood Hits	215	Shared Neighborhood Hits	34
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

PER3_HUMAN
θ value	0.000158464 (rank : 36)	NC score	0.313189 (rank : 37)
Query Neighborhood Hits	94	Target Neighborhood Hits	479	Shared Neighborhood Hits	45
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

PER2_HUMAN
θ value	0.00102713 (rank : 37)	NC score	0.319170 (rank : 36)
Query Neighborhood Hits	94	Target Neighborhood Hits	170	Shared Neighborhood Hits	29
SwissProt Accessions	O15055	Gene names	PER2, KIAA0347
Domain Architecture
Description	Period circadian protein 2.

PER2_MOUSE
θ value	0.00298849 (rank : 38)	NC score	0.295480 (rank : 38)
Query Neighborhood Hits	94	Target Neighborhood Hits	325	Shared Neighborhood Hits	32
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

DDEF2_HUMAN
θ value	0.0148317 (rank : 39)	NC score	0.021747 (rank : 64)
Query Neighborhood Hits	94	Target Neighborhood Hits	599	Shared Neighborhood Hits	12
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

ROBO3_HUMAN
θ value	0.0431538 (rank : 40)	NC score	0.007821 (rank : 89)
Query Neighborhood Hits	94	Target Neighborhood Hits	570	Shared Neighborhood Hits	7
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

SETB1_MOUSE
θ value	0.21417 (rank : 41)	NC score	0.022215 (rank : 63)
Query Neighborhood Hits	94	Target Neighborhood Hits	150	Shared Neighborhood Hits	5
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

SON_HUMAN
θ value	0.365318 (rank : 42)	NC score	0.031434 (rank : 58)
Query Neighborhood Hits	94	Target Neighborhood Hits	1568	Shared Neighborhood Hits	44
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

NF2L2_HUMAN
θ value	0.47712 (rank : 43)	NC score	0.022972 (rank : 62)
Query Neighborhood Hits	94	Target Neighborhood Hits	109	Shared Neighborhood Hits	5
SwissProt Accessions	Q16236, Q96F71	Gene names	NFE2L2, NRF2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2) (HEBP1).

ERF_HUMAN
θ value	0.62314 (rank : 44)	NC score	0.017675 (rank : 72)
Query Neighborhood Hits	94	Target Neighborhood Hits	162	Shared Neighborhood Hits	7
SwissProt Accessions	P50548, Q9UPI7	Gene names	ERF
Domain Architecture
Description	ETS domain-containing transcription factor ERF (Ets2 repressor factor).

ERF_MOUSE
θ value	0.62314 (rank : 45)	NC score	0.017856 (rank : 70)
Query Neighborhood Hits	94	Target Neighborhood Hits	160	Shared Neighborhood Hits	9
SwissProt Accessions	P70459	Gene names	Erf
Domain Architecture
Description	ETS domain-containing transcription factor ERF.

HLF_MOUSE
θ value	0.62314 (rank : 46)	NC score	0.026412 (rank : 59)
Query Neighborhood Hits	94	Target Neighborhood Hits	74	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BW74, Q6PF83	Gene names	Hlf
Domain Architecture	No domain graphic available
Description	Hepatic leukemia factor.

ENAH_MOUSE
θ value	0.813845 (rank : 47)	NC score	0.017381 (rank : 73)
Query Neighborhood Hits	94	Target Neighborhood Hits	919	Shared Neighborhood Hits	19
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

HLF_HUMAN
θ value	0.813845 (rank : 48)	NC score	0.025818 (rank : 60)
Query Neighborhood Hits	94	Target Neighborhood Hits	75	Shared Neighborhood Hits	6
SwissProt Accessions	Q16534	Gene names	HLF
Domain Architecture
Description	Hepatic leukemia factor.

JPH4_HUMAN
θ value	0.813845 (rank : 49)	NC score	0.012692 (rank : 80)
Query Neighborhood Hits	94	Target Neighborhood Hits	103	Shared Neighborhood Hits	3
SwissProt Accessions	Q96JJ6, Q8ND44, Q96DQ0	Gene names	JPH4, JPHL1, KIAA1831
Domain Architecture	No domain graphic available
Description	Junctophilin-4 (Junctophilin-like 1 protein).

MLL3_MOUSE
θ value	1.06291 (rank : 50)	NC score	0.021469 (rank : 66)
Query Neighborhood Hits	94	Target Neighborhood Hits	1399	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

DRD3_MOUSE
θ value	1.38821 (rank : 51)	NC score	0.000490 (rank : 109)
Query Neighborhood Hits	94	Target Neighborhood Hits	709	Shared Neighborhood Hits	2
SwissProt Accessions	P30728	Gene names	Drd3
Domain Architecture
Description	D(3) dopamine receptor.

GPS2_HUMAN
θ value	1.38821 (rank : 52)	NC score	0.019917 (rank : 68)
Query Neighborhood Hits	94	Target Neighborhood Hits	459	Shared Neighborhood Hits	9
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

PASK_HUMAN
θ value	1.38821 (rank : 53)	NC score	0.005154 (rank : 97)
Query Neighborhood Hits	94	Target Neighborhood Hits	857	Shared Neighborhood Hits	13
SwissProt Accessions	Q96RG2, Q86XH6, Q99763, Q9UFR7	Gene names	PASK, KIAA0135
Domain Architecture
Description	PAS domain-containing serine/threonine-protein kinase (EC 2.7.11.1) (PAS-kinase) (PASKIN) (hPASK).

SYN3_MOUSE
θ value	1.81305 (rank : 54)	NC score	0.014985 (rank : 75)
Query Neighborhood Hits	94	Target Neighborhood Hits	200	Shared Neighborhood Hits	12
SwissProt Accessions	Q8JZP2	Gene names	Syn3
Domain Architecture	No domain graphic available
Description	Synapsin-3 (Synapsin III).

CDC20_MOUSE
θ value	2.36792 (rank : 55)	NC score	0.005886 (rank : 94)
Query Neighborhood Hits	94	Target Neighborhood Hits	325	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JJ66, Q3TGP1, Q8BPG4, Q99LK3	Gene names	Cdc20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC) (mmCdc20).

CSF1_MOUSE
θ value	2.36792 (rank : 56)	NC score	0.016649 (rank : 74)
Query Neighborhood Hits	94	Target Neighborhood Hits	83	Shared Neighborhood Hits	7
SwissProt Accessions	P07141, Q8R3C8	Gene names	Csf1, Csfm
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF).

NF2L2_MOUSE
θ value	2.36792 (rank : 57)	NC score	0.017720 (rank : 71)
Query Neighborhood Hits	94	Target Neighborhood Hits	183	Shared Neighborhood Hits	3
SwissProt Accessions	Q60795	Gene names	Nfe2l2, Nrf-2, Nrf2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2).

ZEP2_MOUSE
θ value	2.36792 (rank : 58)	NC score	0.001046 (rank : 106)
Query Neighborhood Hits	94	Target Neighborhood Hits	964	Shared Neighborhood Hits	14
SwissProt Accessions	Q3UHF7, O55140, Q3UVD4, Q3UVH5	Gene names	Hivep2, Mibp1
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Myc intron-binding protein 1) (MIBP-1).

CNOT3_HUMAN
θ value	3.0926 (rank : 59)	NC score	0.012095 (rank : 82)
Query Neighborhood Hits	94	Target Neighborhood Hits	425	Shared Neighborhood Hits	9
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

DDEF1_MOUSE
θ value	3.0926 (rank : 60)	NC score	0.014078 (rank : 78)
Query Neighborhood Hits	94	Target Neighborhood Hits	592	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

K1802_HUMAN
θ value	3.0926 (rank : 61)	NC score	0.013125 (rank : 79)
Query Neighborhood Hits	94	Target Neighborhood Hits	1378	Shared Neighborhood Hits	28
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

K1802_MOUSE
θ value	3.0926 (rank : 62)	NC score	0.008445 (rank : 87)
Query Neighborhood Hits	94	Target Neighborhood Hits	1596	Shared Neighborhood Hits	27
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

HES5_MOUSE
θ value	4.03905 (rank : 63)	NC score	0.065676 (rank : 54)
Query Neighborhood Hits	94	Target Neighborhood Hits	38	Shared Neighborhood Hits	13
SwissProt Accessions	P70120, Q8BVI1	Gene names	Hes5, Hes-5
Domain Architecture
Description	Transcription factor HES-5 (Hairy and enhancer of split 5).

KCNH3_HUMAN
θ value	4.03905 (rank : 64)	NC score	0.004394 (rank : 99)
Query Neighborhood Hits	94	Target Neighborhood Hits	148	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

MAGC1_HUMAN
θ value	4.03905 (rank : 65)	NC score	0.032762 (rank : 57)
Query Neighborhood Hits	94	Target Neighborhood Hits	431	Shared Neighborhood Hits	26
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

NEST_HUMAN
θ value	4.03905 (rank : 66)	NC score	0.001012 (rank : 107)
Query Neighborhood Hits	94	Target Neighborhood Hits	1305	Shared Neighborhood Hits	11
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

PASK_MOUSE
θ value	4.03905 (rank : 67)	NC score	0.003045 (rank : 102)
Query Neighborhood Hits	94	Target Neighborhood Hits	867	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CEE6, Q91YD8	Gene names	Pask, Kiaa0135
Domain Architecture
Description	PAS domain-containing serine/threonine-protein kinase (EC 2.7.11.1) (PAS-kinase) (PASKIN).

R3HD1_HUMAN
θ value	4.03905 (rank : 68)	NC score	0.014469 (rank : 76)
Query Neighborhood Hits	94	Target Neighborhood Hits	203	Shared Neighborhood Hits	9
SwissProt Accessions	Q15032, Q8IW32	Gene names	R3HDM1, KIAA0029, R3HDM
Domain Architecture	No domain graphic available
Description	R3H domain-containing protein 1.

SYP2L_HUMAN
θ value	4.03905 (rank : 69)	NC score	0.008360 (rank : 88)
Query Neighborhood Hits	94	Target Neighborhood Hits	400	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

AMELX_MOUSE
θ value	5.27518 (rank : 70)	NC score	0.012294 (rank : 81)
Query Neighborhood Hits	94	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	P63277, P45559, P70592, Q61293	Gene names	Amelx, Amel
Domain Architecture	No domain graphic available
Description	Amelogenin, X isoform precursor (Leucine-rich amelogenin peptide) (LRAP).

CENG1_MOUSE
θ value	5.27518 (rank : 71)	NC score	0.007748 (rank : 90)
Query Neighborhood Hits	94	Target Neighborhood Hits	531	Shared Neighborhood Hits	9
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

SPG16_MOUSE
θ value	5.27518 (rank : 72)	NC score	0.003314 (rank : 101)
Query Neighborhood Hits	94	Target Neighborhood Hits	377	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K450, Q8C450, Q9CPU8, Q9D522	Gene names	Spag16, Pf20
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 16 protein (PF20 protein homolog).

SSPO_MOUSE
θ value	5.27518 (rank : 73)	NC score	0.000847 (rank : 108)
Query Neighborhood Hits	94	Target Neighborhood Hits	800	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

TENX_HUMAN
θ value	5.27518 (rank : 74)	NC score	0.000077 (rank : 110)
Query Neighborhood Hits	94	Target Neighborhood Hits	789	Shared Neighborhood Hits	9
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

TP53B_MOUSE
θ value	5.27518 (rank : 75)	NC score	0.010048 (rank : 83)
Query Neighborhood Hits	94	Target Neighborhood Hits	644	Shared Neighborhood Hits	16
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

3BP1_HUMAN
θ value	6.88961 (rank : 76)	NC score	0.004960 (rank : 98)
Query Neighborhood Hits	94	Target Neighborhood Hits	376	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

BCL9_HUMAN
θ value	6.88961 (rank : 77)	NC score	0.021030 (rank : 67)
Query Neighborhood Hits	94	Target Neighborhood Hits	1008	Shared Neighborhood Hits	29
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

BCL9_MOUSE
θ value	6.88961 (rank : 78)	NC score	0.021620 (rank : 65)
Query Neighborhood Hits	94	Target Neighborhood Hits	770	Shared Neighborhood Hits	25
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

CENG1_HUMAN
θ value	6.88961 (rank : 79)	NC score	0.008602 (rank : 85)
Query Neighborhood Hits	94	Target Neighborhood Hits	544	Shared Neighborhood Hits	11
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

ENV2_MOUSE
θ value	6.88961 (rank : 80)	NC score	0.008473 (rank : 86)
Query Neighborhood Hits	94	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	P11370, Q61529	Gene names	Fv4, Env
Domain Architecture
Description	Retrovirus-related Env polyprotein from Fv-4 locus.

NEB1_HUMAN
θ value	6.88961 (rank : 81)	NC score	0.001290 (rank : 104)
Query Neighborhood Hits	94	Target Neighborhood Hits	829	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

PRR12_HUMAN
θ value	6.88961 (rank : 82)	NC score	0.018821 (rank : 69)
Query Neighborhood Hits	94	Target Neighborhood Hits	460	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

TRI47_MOUSE
θ value	6.88961 (rank : 83)	NC score	0.005431 (rank : 96)
Query Neighborhood Hits	94	Target Neighborhood Hits	295	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

TROAP_HUMAN
θ value	6.88961 (rank : 84)	NC score	0.022999 (rank : 61)
Query Neighborhood Hits	94	Target Neighborhood Hits	258	Shared Neighborhood Hits	14
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

ABRA_HUMAN
θ value	8.99809 (rank : 85)	NC score	0.014126 (rank : 77)
Query Neighborhood Hits	94	Target Neighborhood Hits	52	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N0Z2	Gene names	ABRA
Domain Architecture	No domain graphic available
Description	Actin-binding Rho-activating protein (Striated muscle activator of Rho-dependent signaling) (STARS).

CCD1A_MOUSE
θ value	8.99809 (rank : 86)	NC score	0.007106 (rank : 91)
Query Neighborhood Hits	94	Target Neighborhood Hits	83	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K1A6, Q2MJB5, Q8R3Z4	Gene names	Cc2d1a
Domain Architecture	No domain graphic available
Description	Coiled-coil and C2 domain-containing protein 1A (Five repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1).

CDC20_HUMAN
θ value	8.99809 (rank : 87)	NC score	0.003765 (rank : 100)
Query Neighborhood Hits	94	Target Neighborhood Hits	329	Shared Neighborhood Hits	4
SwissProt Accessions	Q12834, Q9BW56, Q9UQI9	Gene names	CDC20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC).

CHD1_MOUSE
θ value	8.99809 (rank : 88)	NC score	0.001213 (rank : 105)
Query Neighborhood Hits	94	Target Neighborhood Hits	266	Shared Neighborhood Hits	4
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

EDRF1_HUMAN
θ value	8.99809 (rank : 89)	NC score	0.006590 (rank : 93)
Query Neighborhood Hits	94	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q3B7T1, Q4G190, Q8IZ74, Q9Y3W4	Gene names	EDRF1, C10orf137
Domain Architecture	No domain graphic available
Description	Erythroid differentiation-related factor 1.

MKL2_HUMAN
θ value	8.99809 (rank : 90)	NC score	0.009544 (rank : 84)
Query Neighborhood Hits	94	Target Neighborhood Hits	274	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ULH7, Q68CT1, Q6UB16, Q86WW2, Q8N226	Gene names	MKL2, KIAA1243, MRTFB
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B) (Megakaryoblastic leukemia 2).

NEO1_HUMAN
θ value	8.99809 (rank : 91)	NC score	0.001494 (rank : 103)
Query Neighborhood Hits	94	Target Neighborhood Hits	530	Shared Neighborhood Hits	6
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

OBSCN_HUMAN
θ value	8.99809 (rank : 92)	NC score	-0.002570 (rank : 111)
Query Neighborhood Hits	94	Target Neighborhood Hits	1931	Shared Neighborhood Hits	28
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

PRDM8_MOUSE
θ value	8.99809 (rank : 93)	NC score	0.005559 (rank : 95)
Query Neighborhood Hits	94	Target Neighborhood Hits	176	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BZ97	Gene names	Prdm8
Domain Architecture	No domain graphic available
Description	PR domain zinc finger protein 8 (PR domain-containing protein 8).

ZYX_HUMAN
θ value	8.99809 (rank : 94)	NC score	0.006643 (rank : 92)
Query Neighborhood Hits	94	Target Neighborhood Hits	387	Shared Neighborhood Hits	14
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

HEY1_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.081410 (rank : 42)
Query Neighborhood Hits	94	Target Neighborhood Hits	82	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y5J3, Q5TZS3, Q9NYP4	Gene names	HEY1, CHF2, HESR1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).

HEY1_MOUSE
θ value	θ > 10 (rank : 96)	NC score	0.085320 (rank : 41)
Query Neighborhood Hits	94	Target Neighborhood Hits	69	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WV93	Gene names	Hey1, Hesr1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).

HEY2_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.092271 (rank : 39)
Query Neighborhood Hits	94	Target Neighborhood Hits	77	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

HEY2_MOUSE
θ value	θ > 10 (rank : 98)	NC score	0.090280 (rank : 40)
Query Neighborhood Hits	94	Target Neighborhood Hits	80	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QUS4, Q3TZ99, Q8CD44	Gene names	Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).

MITF_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.074516 (rank : 46)
Query Neighborhood Hits	94	Target Neighborhood Hits	113	Shared Neighborhood Hits	14
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MITF_MOUSE
θ value	θ > 10 (rank : 100)	NC score	0.076552 (rank : 45)
Query Neighborhood Hits	94	Target Neighborhood Hits	115	Shared Neighborhood Hits	15
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MLX_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.066027 (rank : 53)
Query Neighborhood Hits	94	Target Neighborhood Hits	95	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MLX_MOUSE
θ value	θ > 10 (rank : 102)	NC score	0.066095 (rank : 52)
Query Neighborhood Hits	94	Target Neighborhood Hits	100	Shared Neighborhood Hits	12
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MYCL1_MOUSE
θ value	θ > 10 (rank : 103)	NC score	0.050907 (rank : 56)
Query Neighborhood Hits	94	Target Neighborhood Hits	123	Shared Neighborhood Hits	10
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

TCFL5_HUMAN
θ value	θ > 10 (rank : 104)	NC score	0.078190 (rank : 43)
Query Neighborhood Hits	94	Target Neighborhood Hits	43	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UL49, O94771, Q9BYW0	Gene names	TCFL5, CHA, E2BP1
Domain Architecture	No domain graphic available
Description	Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).

TFE3_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.077068 (rank : 44)
Query Neighborhood Hits	94	Target Neighborhood Hits	190	Shared Neighborhood Hits	12
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

TFEB_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.071448 (rank : 47)
Query Neighborhood Hits	94	Target Neighborhood Hits	111	Shared Neighborhood Hits	13
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

TFEB_MOUSE
θ value	θ > 10 (rank : 107)	NC score	0.071256 (rank : 48)
Query Neighborhood Hits	94	Target Neighborhood Hits	119	Shared Neighborhood Hits	15
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

USF1_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.070965 (rank : 49)
Query Neighborhood Hits	94	Target Neighborhood Hits	70	Shared Neighborhood Hits	9
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF1_MOUSE
θ value	θ > 10 (rank : 109)	NC score	0.070933 (rank : 50)
Query Neighborhood Hits	94	Target Neighborhood Hits	71	Shared Neighborhood Hits	9
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF2_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.067952 (rank : 51)
Query Neighborhood Hits	94	Target Neighborhood Hits	155	Shared Neighborhood Hits	8
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

USF2_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.063357 (rank : 55)
Query Neighborhood Hits	94	Target Neighborhood Hits	173	Shared Neighborhood Hits	9
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

Hits sorted by NC score

EPAS1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	94	Target Neighborhood Hits	94	Shared Neighborhood Hits	94
SwissProt Accessions	P97481, O08787, O55046	Gene names	Epas1, Hif2a
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Hypoxia- inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (MHLF) (HIF-related factor) (HRF).

EPAS1_HUMAN
NC score	0.994197 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	94	Target Neighborhood Hits	76	Shared Neighborhood Hits	44
SwissProt Accessions	Q99814, Q86VA2, Q99630	Gene names	EPAS1, HIF2A
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Member of PAS protein 2) (MOP2) (Hypoxia-inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (HLF).

HIF1A_MOUSE
NC score	0.977646 (rank : 3)	θ value	2.04462e-161 (rank : 4)
Query Neighborhood Hits	94	Target Neighborhood Hits	90	Shared Neighborhood Hits	40
SwissProt Accessions	Q61221, O08741, O08993, Q61664, Q61665, Q8C681, Q8CC19, Q8CCB6, Q8R385, Q9CYA8	Gene names	Hif1a
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein).

HIF1A_HUMAN
NC score	0.975288 (rank : 4)	θ value	2.04462e-161 (rank : 3)
Query Neighborhood Hits	94	Target Neighborhood Hits	118	Shared Neighborhood Hits	41
SwissProt Accessions	Q16665, Q96PT9, Q9UPB1	Gene names	HIF1A
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein) (Member of PAS protein 1) (MOP1).

SIM2_MOUSE
NC score	0.923554 (rank : 5)	θ value	2.32439e-64 (rank : 5)
Query Neighborhood Hits	94	Target Neighborhood Hits	75	Shared Neighborhood Hits	37
SwissProt Accessions	Q61079, O35391, Q61046, Q61904	Gene names	Sim2
Domain Architecture
Description	Single-minded homolog 2 (SIM transcription factor) (mSIM).

SIM2_HUMAN
NC score	0.923527 (rank : 6)	θ value	4.10295e-61 (rank : 8)
Query Neighborhood Hits	94	Target Neighborhood Hits	76	Shared Neighborhood Hits	39
SwissProt Accessions	Q14190, O60766, Q15470, Q15471, Q15472, Q15473, Q16532	Gene names	SIM2
Domain Architecture
Description	Single-minded homolog 2.

SIM1_HUMAN
NC score	0.921705 (rank : 7)	θ value	3.03575e-64 (rank : 6)
Query Neighborhood Hits	94	Target Neighborhood Hits	62	Shared Neighborhood Hits	39
SwissProt Accessions	P81133, Q5TDP7	Gene names	SIM1
Domain Architecture
Description	Single-minded homolog 1.

SIM1_MOUSE
NC score	0.920668 (rank : 8)	θ value	3.35642e-63 (rank : 7)
Query Neighborhood Hits	94	Target Neighborhood Hits	69	Shared Neighborhood Hits	40
SwissProt Accessions	Q61045, O70284, P70183	Gene names	Sim1
Domain Architecture
Description	Single-minded homolog 1 (mSIM1).

NPAS1_MOUSE
NC score	0.900850 (rank : 9)	θ value	1.23823e-49 (rank : 11)
Query Neighborhood Hits	94	Target Neighborhood Hits	63	Shared Neighborhood Hits	32
SwissProt Accessions	P97459	Gene names	Npas1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1).

NPAS3_MOUSE
NC score	0.899814 (rank : 10)	θ value	1.78386e-56 (rank : 10)
Query Neighborhood Hits	94	Target Neighborhood Hits	103	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QZQ0, Q9EQP4	Gene names	Npas3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

NPAS3_HUMAN
NC score	0.899765 (rank : 11)	θ value	1.36585e-56 (rank : 9)
Query Neighborhood Hits	94	Target Neighborhood Hits	81	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IXF0, Q86US6, Q86US7, Q8IXF2, Q9BY81, Q9H323, Q9Y4L8	Gene names	NPAS3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

NPAS1_HUMAN
NC score	0.899572 (rank : 12)	θ value	6.7944e-48 (rank : 12)
Query Neighborhood Hits	94	Target Neighborhood Hits	77	Shared Neighborhood Hits	34
SwissProt Accessions	Q99742, Q99632, Q9BY83	Gene names	NPAS1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1) (Member of PAS protein 5) (MOP5).

BMAL1_HUMAN
NC score	0.829322 (rank : 13)	θ value	1.98606e-31 (rank : 15)
Query Neighborhood Hits	94	Target Neighborhood Hits	115	Shared Neighborhood Hits	40
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

BMAL1_MOUSE
NC score	0.826994 (rank : 14)	θ value	3.3877e-31 (rank : 16)
Query Neighborhood Hits	94	Target Neighborhood Hits	121	Shared Neighborhood Hits	40
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

AHR_HUMAN
NC score	0.815426 (rank : 15)	θ value	9.87957e-23 (rank : 24)
Query Neighborhood Hits	94	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	P35869, Q13728, Q13803, Q13804	Gene names	AHR
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

AHR_MOUSE
NC score	0.812231 (rank : 16)	θ value	4.43474e-23 (rank : 23)
Query Neighborhood Hits	94	Target Neighborhood Hits	55	Shared Neighborhood Hits	35
SwissProt Accessions	P30561, Q8QZX6, Q8R4S3, Q99P79, Q9QVY1	Gene names	Ahr
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

CLOCK_HUMAN
NC score	0.807441 (rank : 17)	θ value	4.89182e-30 (rank : 19)
Query Neighborhood Hits	94	Target Neighborhood Hits	127	Shared Neighborhood Hits	39
SwissProt Accessions	O15516, O14516, Q9UIT8	Gene names	CLOCK, KIAA0334
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (hCLOCK).

CLOCK_MOUSE
NC score	0.803980 (rank : 18)	θ value	4.14116e-29 (rank : 22)
Query Neighborhood Hits	94	Target Neighborhood Hits	148	Shared Neighborhood Hits	39
SwissProt Accessions	O08785	Gene names	Clock
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (mCLOCK).

NPAS2_MOUSE
NC score	0.796372 (rank : 19)	θ value	2.86786e-30 (rank : 18)
Query Neighborhood Hits	94	Target Neighborhood Hits	132	Shared Neighborhood Hits	41
SwissProt Accessions	P97460	Gene names	Npas2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2).

ARNT2_HUMAN
NC score	0.794139 (rank : 20)	θ value	8.91499e-32 (rank : 14)
Query Neighborhood Hits	94	Target Neighborhood Hits	109	Shared Neighborhood Hits	38
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT2_MOUSE
NC score	0.793341 (rank : 21)	θ value	6.82597e-32 (rank : 13)
Query Neighborhood Hits	94	Target Neighborhood Hits	115	Shared Neighborhood Hits	38
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

NPAS2_HUMAN
NC score	0.789720 (rank : 22)	θ value	1.4233e-29 (rank : 21)
Query Neighborhood Hits	94	Target Neighborhood Hits	150	Shared Neighborhood Hits	40
SwissProt Accessions	Q99743, Q99629	Gene names	NPAS2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2) (Member of PAS protein 4) (MOP4).

ARNT_HUMAN
NC score	0.788681 (rank : 23)	θ value	2.86786e-30 (rank : 17)
Query Neighborhood Hits	94	Target Neighborhood Hits	109	Shared Neighborhood Hits	39
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

ARNT_MOUSE
NC score	0.775106 (rank : 24)	θ value	8.3442e-30 (rank : 20)
Query Neighborhood Hits	94	Target Neighborhood Hits	213	Shared Neighborhood Hits	40
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

NPAS4_HUMAN
NC score	0.678107 (rank : 25)	θ value	1.13037e-18 (rank : 25)
Query Neighborhood Hits	94	Target Neighborhood Hits	214	Shared Neighborhood Hits	45
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

NPAS4_MOUSE
NC score	0.661451 (rank : 26)	θ value	1.24977e-17 (rank : 26)
Query Neighborhood Hits	94	Target Neighborhood Hits	245	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

NCOA1_MOUSE
NC score	0.620193 (rank : 27)	θ value	3.89403e-11 (rank : 31)
Query Neighborhood Hits	94	Target Neighborhood Hits	196	Shared Neighborhood Hits	36
SwissProt Accessions	P70365, P70366, Q61202, Q8CBI9	Gene names	Ncoa1, Src1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (Nuclear receptor coactivator protein 1) (mNRC-1).

NCOA1_HUMAN
NC score	0.617665 (rank : 28)	θ value	1.74796e-11 (rank : 30)
Query Neighborhood Hits	94	Target Neighborhood Hits	198	Shared Neighborhood Hits	34
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

NCOA3_HUMAN
NC score	0.569862 (rank : 29)	θ value	7.84624e-12 (rank : 29)
Query Neighborhood Hits	94	Target Neighborhood Hits	171	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7	Gene names	NCOA3, AIB1, RAC3, TRAM1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).

NCOA2_MOUSE
NC score	0.567186 (rank : 30)	θ value	6.41864e-14 (rank : 27)
Query Neighborhood Hits	94	Target Neighborhood Hits	281	Shared Neighborhood Hits	39
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

NCOA2_HUMAN
NC score	0.566473 (rank : 31)	θ value	1.09485e-13 (rank : 28)
Query Neighborhood Hits	94	Target Neighborhood Hits	281	Shared Neighborhood Hits	36
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

NCOA3_MOUSE
NC score	0.533502 (rank : 32)	θ value	3.29651e-10 (rank : 32)
Query Neighborhood Hits	94	Target Neighborhood Hits	203	Shared Neighborhood Hits	36
SwissProt Accessions	O09000, Q9CRD5	Gene names	Ncoa3, Aib1, Pcip, Rac3, Tram1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein homolog) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP- interacting protein) (p/CIP) (pCIP).

PER3_MOUSE
NC score	0.348456 (rank : 33)	θ value	6.43352e-06 (rank : 34)
Query Neighborhood Hits	94	Target Neighborhood Hits	85	Shared Neighborhood Hits	30
SwissProt Accessions	O70361	Gene names	Per3
Domain Architecture
Description	Period circadian protein 3 (mPER3).

PER1_HUMAN
NC score	0.326997 (rank : 34)	θ value	8.40245e-06 (rank : 35)
Query Neighborhood Hits	94	Target Neighborhood Hits	215	Shared Neighborhood Hits	34
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

PER1_MOUSE
NC score	0.325698 (rank : 35)	θ value	3.77169e-06 (rank : 33)
Query Neighborhood Hits	94	Target Neighborhood Hits	235	Shared Neighborhood Hits	39
SwissProt Accessions	O35973	Gene names	Per1, Per, Rigui
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (mPER) (M-Rigui).

PER2_HUMAN
NC score	0.319170 (rank : 36)	θ value	0.00102713 (rank : 37)
Query Neighborhood Hits	94	Target Neighborhood Hits	170	Shared Neighborhood Hits	29
SwissProt Accessions	O15055	Gene names	PER2, KIAA0347
Domain Architecture
Description	Period circadian protein 2.

PER3_HUMAN
NC score	0.313189 (rank : 37)	θ value	0.000158464 (rank : 36)
Query Neighborhood Hits	94	Target Neighborhood Hits	479	Shared Neighborhood Hits	45
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

PER2_MOUSE
NC score	0.295480 (rank : 38)	θ value	0.00298849 (rank : 38)
Query Neighborhood Hits	94	Target Neighborhood Hits	325	Shared Neighborhood Hits	32
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

HEY2_HUMAN
NC score	0.092271 (rank : 39)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	94	Target Neighborhood Hits	77	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

HEY2_MOUSE
NC score	0.090280 (rank : 40)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	94	Target Neighborhood Hits	80	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QUS4, Q3TZ99, Q8CD44	Gene names	Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).

HEY1_MOUSE
NC score	0.085320 (rank : 41)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	94	Target Neighborhood Hits	69	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WV93	Gene names	Hey1, Hesr1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).

HEY1_HUMAN
NC score	0.081410 (rank : 42)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	94	Target Neighborhood Hits	82	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y5J3, Q5TZS3, Q9NYP4	Gene names	HEY1, CHF2, HESR1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).

TCFL5_HUMAN
NC score	0.078190 (rank : 43)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	94	Target Neighborhood Hits	43	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UL49, O94771, Q9BYW0	Gene names	TCFL5, CHA, E2BP1
Domain Architecture	No domain graphic available
Description	Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).

TFE3_HUMAN
NC score	0.077068 (rank : 44)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	94	Target Neighborhood Hits	190	Shared Neighborhood Hits	12
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

MITF_MOUSE
NC score	0.076552 (rank : 45)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	94	Target Neighborhood Hits	115	Shared Neighborhood Hits	15
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MITF_HUMAN
NC score	0.074516 (rank : 46)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	94	Target Neighborhood Hits	113	Shared Neighborhood Hits	14
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

TFEB_HUMAN
NC score	0.071448 (rank : 47)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	94	Target Neighborhood Hits	111	Shared Neighborhood Hits	13
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

TFEB_MOUSE
NC score	0.071256 (rank : 48)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	94	Target Neighborhood Hits	119	Shared Neighborhood Hits	15
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

USF1_HUMAN
NC score	0.070965 (rank : 49)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	94	Target Neighborhood Hits	70	Shared Neighborhood Hits	9
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF1_MOUSE
NC score	0.070933 (rank : 50)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	94	Target Neighborhood Hits	71	Shared Neighborhood Hits	9
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF2_HUMAN
NC score	0.067952 (rank : 51)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	94	Target Neighborhood Hits	155	Shared Neighborhood Hits	8
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

MLX_MOUSE
NC score	0.066095 (rank : 52)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	94	Target Neighborhood Hits	100	Shared Neighborhood Hits	12
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MLX_HUMAN
NC score	0.066027 (rank : 53)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	94	Target Neighborhood Hits	95	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

HES5_MOUSE
NC score	0.065676 (rank : 54)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	94	Target Neighborhood Hits	38	Shared Neighborhood Hits	13
SwissProt Accessions	P70120, Q8BVI1	Gene names	Hes5, Hes-5
Domain Architecture
Description	Transcription factor HES-5 (Hairy and enhancer of split 5).

USF2_MOUSE
NC score	0.063357 (rank : 55)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	94	Target Neighborhood Hits	173	Shared Neighborhood Hits	9
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

MYCL1_MOUSE
NC score	0.050907 (rank : 56)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	94	Target Neighborhood Hits	123	Shared Neighborhood Hits	10
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MAGC1_HUMAN
NC score	0.032762 (rank : 57)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	94	Target Neighborhood Hits	431	Shared Neighborhood Hits	26
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

SON_HUMAN
NC score	0.031434 (rank : 58)	θ value	0.365318 (rank : 42)
Query Neighborhood Hits	94	Target Neighborhood Hits	1568	Shared Neighborhood Hits	44
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

HLF_MOUSE
NC score	0.026412 (rank : 59)	θ value	0.62314 (rank : 46)
Query Neighborhood Hits	94	Target Neighborhood Hits	74	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BW74, Q6PF83	Gene names	Hlf
Domain Architecture	No domain graphic available
Description	Hepatic leukemia factor.

HLF_HUMAN
NC score	0.025818 (rank : 60)	θ value	0.813845 (rank : 48)
Query Neighborhood Hits	94	Target Neighborhood Hits	75	Shared Neighborhood Hits	6
SwissProt Accessions	Q16534	Gene names	HLF
Domain Architecture
Description	Hepatic leukemia factor.

TROAP_HUMAN
NC score	0.022999 (rank : 61)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	94	Target Neighborhood Hits	258	Shared Neighborhood Hits	14
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

NF2L2_HUMAN
NC score	0.022972 (rank : 62)	θ value	0.47712 (rank : 43)
Query Neighborhood Hits	94	Target Neighborhood Hits	109	Shared Neighborhood Hits	5
SwissProt Accessions	Q16236, Q96F71	Gene names	NFE2L2, NRF2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2) (HEBP1).

SETB1_MOUSE
NC score	0.022215 (rank : 63)	θ value	0.21417 (rank : 41)
Query Neighborhood Hits	94	Target Neighborhood Hits	150	Shared Neighborhood Hits	5
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

DDEF2_HUMAN
NC score	0.021747 (rank : 64)	θ value	0.0148317 (rank : 39)
Query Neighborhood Hits	94	Target Neighborhood Hits	599	Shared Neighborhood Hits	12
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

BCL9_MOUSE
NC score	0.021620 (rank : 65)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	94	Target Neighborhood Hits	770	Shared Neighborhood Hits	25
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

MLL3_MOUSE
NC score	0.021469 (rank : 66)	θ value	1.06291 (rank : 50)
Query Neighborhood Hits	94	Target Neighborhood Hits	1399	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

BCL9_HUMAN
NC score	0.021030 (rank : 67)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	94	Target Neighborhood Hits	1008	Shared Neighborhood Hits	29
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

GPS2_HUMAN
NC score	0.019917 (rank : 68)	θ value	1.38821 (rank : 52)
Query Neighborhood Hits	94	Target Neighborhood Hits	459	Shared Neighborhood Hits	9
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

PRR12_HUMAN
NC score	0.018821 (rank : 69)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	94	Target Neighborhood Hits	460	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

ERF_MOUSE
NC score	0.017856 (rank : 70)	θ value	0.62314 (rank : 45)
Query Neighborhood Hits	94	Target Neighborhood Hits	160	Shared Neighborhood Hits	9
SwissProt Accessions	P70459	Gene names	Erf
Domain Architecture
Description	ETS domain-containing transcription factor ERF.

NF2L2_MOUSE
NC score	0.017720 (rank : 71)	θ value	2.36792 (rank : 57)
Query Neighborhood Hits	94	Target Neighborhood Hits	183	Shared Neighborhood Hits	3
SwissProt Accessions	Q60795	Gene names	Nfe2l2, Nrf-2, Nrf2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2).

ERF_HUMAN
NC score	0.017675 (rank : 72)	θ value	0.62314 (rank : 44)
Query Neighborhood Hits	94	Target Neighborhood Hits	162	Shared Neighborhood Hits	7
SwissProt Accessions	P50548, Q9UPI7	Gene names	ERF
Domain Architecture
Description	ETS domain-containing transcription factor ERF (Ets2 repressor factor).

ENAH_MOUSE
NC score	0.017381 (rank : 73)	θ value	0.813845 (rank : 47)
Query Neighborhood Hits	94	Target Neighborhood Hits	919	Shared Neighborhood Hits	19
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

CSF1_MOUSE
NC score	0.016649 (rank : 74)	θ value	2.36792 (rank : 56)
Query Neighborhood Hits	94	Target Neighborhood Hits	83	Shared Neighborhood Hits	7
SwissProt Accessions	P07141, Q8R3C8	Gene names	Csf1, Csfm
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF).

SYN3_MOUSE
NC score	0.014985 (rank : 75)	θ value	1.81305 (rank : 54)
Query Neighborhood Hits	94	Target Neighborhood Hits	200	Shared Neighborhood Hits	12
SwissProt Accessions	Q8JZP2	Gene names	Syn3
Domain Architecture	No domain graphic available
Description	Synapsin-3 (Synapsin III).

R3HD1_HUMAN
NC score	0.014469 (rank : 76)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	94	Target Neighborhood Hits	203	Shared Neighborhood Hits	9
SwissProt Accessions	Q15032, Q8IW32	Gene names	R3HDM1, KIAA0029, R3HDM
Domain Architecture	No domain graphic available
Description	R3H domain-containing protein 1.

ABRA_HUMAN
NC score	0.014126 (rank : 77)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	94	Target Neighborhood Hits	52	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N0Z2	Gene names	ABRA
Domain Architecture	No domain graphic available
Description	Actin-binding Rho-activating protein (Striated muscle activator of Rho-dependent signaling) (STARS).

DDEF1_MOUSE
NC score	0.014078 (rank : 78)	θ value	3.0926 (rank : 60)
Query Neighborhood Hits	94	Target Neighborhood Hits	592	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

K1802_HUMAN
NC score	0.013125 (rank : 79)	θ value	3.0926 (rank : 61)
Query Neighborhood Hits	94	Target Neighborhood Hits	1378	Shared Neighborhood Hits	28
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

JPH4_HUMAN
NC score	0.012692 (rank : 80)	θ value	0.813845 (rank : 49)
Query Neighborhood Hits	94	Target Neighborhood Hits	103	Shared Neighborhood Hits	3
SwissProt Accessions	Q96JJ6, Q8ND44, Q96DQ0	Gene names	JPH4, JPHL1, KIAA1831
Domain Architecture	No domain graphic available
Description	Junctophilin-4 (Junctophilin-like 1 protein).

AMELX_MOUSE
NC score	0.012294 (rank : 81)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	94	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	P63277, P45559, P70592, Q61293	Gene names	Amelx, Amel
Domain Architecture	No domain graphic available
Description	Amelogenin, X isoform precursor (Leucine-rich amelogenin peptide) (LRAP).

CNOT3_HUMAN
NC score	0.012095 (rank : 82)	θ value	3.0926 (rank : 59)
Query Neighborhood Hits	94	Target Neighborhood Hits	425	Shared Neighborhood Hits	9
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

TP53B_MOUSE
NC score	0.010048 (rank : 83)	θ value	5.27518 (rank : 75)
Query Neighborhood Hits	94	Target Neighborhood Hits	644	Shared Neighborhood Hits	16
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

MKL2_HUMAN
NC score	0.009544 (rank : 84)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	94	Target Neighborhood Hits	274	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ULH7, Q68CT1, Q6UB16, Q86WW2, Q8N226	Gene names	MKL2, KIAA1243, MRTFB
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B) (Megakaryoblastic leukemia 2).

CENG1_HUMAN
NC score	0.008602 (rank : 85)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	94	Target Neighborhood Hits	544	Shared Neighborhood Hits	11
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

ENV2_MOUSE
NC score	0.008473 (rank : 86)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	94	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	P11370, Q61529	Gene names	Fv4, Env
Domain Architecture
Description	Retrovirus-related Env polyprotein from Fv-4 locus.

K1802_MOUSE
NC score	0.008445 (rank : 87)	θ value	3.0926 (rank : 62)
Query Neighborhood Hits	94	Target Neighborhood Hits	1596	Shared Neighborhood Hits	27
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

SYP2L_HUMAN
NC score	0.008360 (rank : 88)	θ value	4.03905 (rank : 69)
Query Neighborhood Hits	94	Target Neighborhood Hits	400	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

ROBO3_HUMAN
NC score	0.007821 (rank : 89)	θ value	0.0431538 (rank : 40)
Query Neighborhood Hits	94	Target Neighborhood Hits	570	Shared Neighborhood Hits	7
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

CENG1_MOUSE
NC score	0.007748 (rank : 90)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	94	Target Neighborhood Hits	531	Shared Neighborhood Hits	9
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

CCD1A_MOUSE
NC score	0.007106 (rank : 91)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	94	Target Neighborhood Hits	83	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K1A6, Q2MJB5, Q8R3Z4	Gene names	Cc2d1a
Domain Architecture	No domain graphic available
Description	Coiled-coil and C2 domain-containing protein 1A (Five repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1).

ZYX_HUMAN
NC score	0.006643 (rank : 92)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	94	Target Neighborhood Hits	387	Shared Neighborhood Hits	14
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

EDRF1_HUMAN
NC score	0.006590 (rank : 93)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	94	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q3B7T1, Q4G190, Q8IZ74, Q9Y3W4	Gene names	EDRF1, C10orf137
Domain Architecture	No domain graphic available
Description	Erythroid differentiation-related factor 1.

CDC20_MOUSE
NC score	0.005886 (rank : 94)	θ value	2.36792 (rank : 55)
Query Neighborhood Hits	94	Target Neighborhood Hits	325	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JJ66, Q3TGP1, Q8BPG4, Q99LK3	Gene names	Cdc20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC) (mmCdc20).

PRDM8_MOUSE
NC score	0.005559 (rank : 95)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	94	Target Neighborhood Hits	176	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BZ97	Gene names	Prdm8
Domain Architecture	No domain graphic available
Description	PR domain zinc finger protein 8 (PR domain-containing protein 8).

TRI47_MOUSE
NC score	0.005431 (rank : 96)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	94	Target Neighborhood Hits	295	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

PASK_HUMAN
NC score	0.005154 (rank : 97)	θ value	1.38821 (rank : 53)
Query Neighborhood Hits	94	Target Neighborhood Hits	857	Shared Neighborhood Hits	13
SwissProt Accessions	Q96RG2, Q86XH6, Q99763, Q9UFR7	Gene names	PASK, KIAA0135
Domain Architecture
Description	PAS domain-containing serine/threonine-protein kinase (EC 2.7.11.1) (PAS-kinase) (PASKIN) (hPASK).

3BP1_HUMAN
NC score	0.004960 (rank : 98)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	94	Target Neighborhood Hits	376	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

KCNH3_HUMAN
NC score	0.004394 (rank : 99)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	94	Target Neighborhood Hits	148	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

CDC20_HUMAN
NC score	0.003765 (rank : 100)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	94	Target Neighborhood Hits	329	Shared Neighborhood Hits	4
SwissProt Accessions	Q12834, Q9BW56, Q9UQI9	Gene names	CDC20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC).

SPG16_MOUSE
NC score	0.003314 (rank : 101)	θ value	5.27518 (rank : 72)
Query Neighborhood Hits	94	Target Neighborhood Hits	377	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K450, Q8C450, Q9CPU8, Q9D522	Gene names	Spag16, Pf20
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 16 protein (PF20 protein homolog).

PASK_MOUSE
NC score	0.003045 (rank : 102)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	94	Target Neighborhood Hits	867	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CEE6, Q91YD8	Gene names	Pask, Kiaa0135
Domain Architecture
Description	PAS domain-containing serine/threonine-protein kinase (EC 2.7.11.1) (PAS-kinase) (PASKIN).

NEO1_HUMAN
NC score	0.001494 (rank : 103)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	94	Target Neighborhood Hits	530	Shared Neighborhood Hits	6
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

NEB1_HUMAN
NC score	0.001290 (rank : 104)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	94	Target Neighborhood Hits	829	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

CHD1_MOUSE
NC score	0.001213 (rank : 105)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	94	Target Neighborhood Hits	266	Shared Neighborhood Hits	4
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

ZEP2_MOUSE
NC score	0.001046 (rank : 106)	θ value	2.36792 (rank : 58)
Query Neighborhood Hits	94	Target Neighborhood Hits	964	Shared Neighborhood Hits	14
SwissProt Accessions	Q3UHF7, O55140, Q3UVD4, Q3UVH5	Gene names	Hivep2, Mibp1
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Myc intron-binding protein 1) (MIBP-1).

NEST_HUMAN
NC score	0.001012 (rank : 107)	θ value	4.03905 (rank : 66)
Query Neighborhood Hits	94	Target Neighborhood Hits	1305	Shared Neighborhood Hits	11
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

SSPO_MOUSE
NC score	0.000847 (rank : 108)	θ value	5.27518 (rank : 73)
Query Neighborhood Hits	94	Target Neighborhood Hits	800	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

DRD3_MOUSE
NC score	0.000490 (rank : 109)	θ value	1.38821 (rank : 51)
Query Neighborhood Hits	94	Target Neighborhood Hits	709	Shared Neighborhood Hits	2
SwissProt Accessions	P30728	Gene names	Drd3
Domain Architecture
Description	D(3) dopamine receptor.

TENX_HUMAN
NC score	0.000077 (rank : 110)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	94	Target Neighborhood Hits	789	Shared Neighborhood Hits	9
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

OBSCN_HUMAN
NC score	-0.002570 (rank : 111)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	94	Target Neighborhood Hits	1931	Shared Neighborhood Hits	28
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).