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Network neighborhood for query Sequence : AKP8L_HUMAN

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AKP8L_HUMAN
SwissProt Accessions	Q9ULX6, O94792, Q96J58, Q9NRQ0, Q9UGM0	Gene names	AKAP8L, NAKAP95
Domain Architecture
Description	A-kinase anchor protein 8-like (AKAP8-like protein) (Neighbor of A- kinase-anchoring protein 95) (Neighbor of AKAP95) (Homologous to AKAP95 protein) (HA95) (Helicase A-binding protein 95) (HAP95).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

AKP8L_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	89	Target Neighborhood Hits	89	Shared Neighborhood Hits	89
SwissProt Accessions	Q9ULX6, O94792, Q96J58, Q9NRQ0, Q9UGM0	Gene names	AKAP8L, NAKAP95
Domain Architecture
Description	A-kinase anchor protein 8-like (AKAP8-like protein) (Neighbor of A- kinase-anchoring protein 95) (Neighbor of AKAP95) (Homologous to AKAP95 protein) (HA95) (Helicase A-binding protein 95) (HAP95).

AKP8L_MOUSE
θ value	0 (rank : 2)	NC score	0.985671 (rank : 2)
Query Neighborhood Hits	89	Target Neighborhood Hits	95	Shared Neighborhood Hits	50
SwissProt Accessions	Q9R0L7	Gene names	Akap8l, Nakap95
Domain Architecture
Description	A-kinase anchor protein 8-like (AKAP8-like protein) (Neighbor of A- kinase-anchoring protein 95) (Neighbor of AKAP95).

AKAP8_HUMAN
θ value	1.15359e-63 (rank : 3)	NC score	0.857550 (rank : 4)
Query Neighborhood Hits	89	Target Neighborhood Hits	166	Shared Neighborhood Hits	15
SwissProt Accessions	O43823	Gene names	AKAP8, AKAP95
Domain Architecture
Description	A-kinase anchor protein 8 (A-kinase anchor protein 95 kDa) (AKAP 95).

AKAP8_MOUSE
θ value	2.03627e-60 (rank : 4)	NC score	0.875568 (rank : 3)
Query Neighborhood Hits	89	Target Neighborhood Hits	76	Shared Neighborhood Hits	8
SwissProt Accessions	Q9DBR0, Q9R0L8	Gene names	Akap8, Akap95
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 8 (A-kinase anchor protein 95 kDa) (AKAP 95).

ZN326_HUMAN
θ value	1.08979e-29 (rank : 5)	NC score	0.743217 (rank : 5)
Query Neighborhood Hits	89	Target Neighborhood Hits	90	Shared Neighborhood Hits	13
SwissProt Accessions	Q5BKZ1, Q5VW93, Q5VW94, Q5VW96, Q5VW97, Q6NSA2, Q7Z638, Q7Z6C2	Gene names	ZNF326
Domain Architecture	No domain graphic available
Description	Zinc finger protein 326.

ZN326_MOUSE
θ value	3.50572e-28 (rank : 6)	NC score	0.738700 (rank : 6)
Query Neighborhood Hits	89	Target Neighborhood Hits	117	Shared Neighborhood Hits	19
SwissProt Accessions	O88291, Q8BSJ5, Q8K1X9, Q9CYG9	Gene names	Znf326, Zan75, Zfp326
Domain Architecture	No domain graphic available
Description	Zinc finger protein 326 (Zinc finger protein-associated with nuclear matrix of 75 kDa).

RRBP1_MOUSE
θ value	0.00134147 (rank : 7)	NC score	0.060356 (rank : 13)
Query Neighborhood Hits	89	Target Neighborhood Hits	1650	Shared Neighborhood Hits	47
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

LEO1_HUMAN
θ value	0.0736092 (rank : 8)	NC score	0.077992 (rank : 8)
Query Neighborhood Hits	89	Target Neighborhood Hits	958	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

LEO1_MOUSE
θ value	0.0961366 (rank : 9)	NC score	0.082714 (rank : 7)
Query Neighborhood Hits	89	Target Neighborhood Hits	946	Shared Neighborhood Hits	33
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

RRBP1_HUMAN
θ value	0.0961366 (rank : 10)	NC score	0.057731 (rank : 19)
Query Neighborhood Hits	89	Target Neighborhood Hits	1306	Shared Neighborhood Hits	43
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

IWS1_MOUSE
θ value	0.163984 (rank : 11)	NC score	0.060661 (rank : 12)
Query Neighborhood Hits	89	Target Neighborhood Hits	1258	Shared Neighborhood Hits	33
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MPP8_HUMAN
θ value	0.163984 (rank : 12)	NC score	0.039907 (rank : 32)
Query Neighborhood Hits	89	Target Neighborhood Hits	948	Shared Neighborhood Hits	27
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

OXRP_HUMAN
θ value	0.47712 (rank : 13)	NC score	0.043266 (rank : 28)
Query Neighborhood Hits	89	Target Neighborhood Hits	544	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

PHLB2_HUMAN
θ value	0.47712 (rank : 14)	NC score	0.044087 (rank : 27)
Query Neighborhood Hits	89	Target Neighborhood Hits	964	Shared Neighborhood Hits	27
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

COFA1_HUMAN
θ value	0.62314 (rank : 15)	NC score	0.020932 (rank : 62)
Query Neighborhood Hits	89	Target Neighborhood Hits	292	Shared Neighborhood Hits	10
SwissProt Accessions	P39059, Q5T6J4, Q9Y4W4	Gene names	COL15A1
Domain Architecture
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV) (Restin) (Related to endostatin)].

GP176_HUMAN
θ value	0.62314 (rank : 16)	NC score	0.015856 (rank : 72)
Query Neighborhood Hits	89	Target Neighborhood Hits	522	Shared Neighborhood Hits	3
SwissProt Accessions	Q14439, Q6NXF6	Gene names	GPR176
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 176 (HB-954).

TRIM1_HUMAN
θ value	0.62314 (rank : 17)	NC score	0.029617 (rank : 44)
Query Neighborhood Hits	89	Target Neighborhood Hits	345	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRIM1_MOUSE
θ value	0.62314 (rank : 18)	NC score	0.029129 (rank : 45)
Query Neighborhood Hits	89	Target Neighborhood Hits	361	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

ZN638_HUMAN
θ value	0.813845 (rank : 19)	NC score	0.060156 (rank : 14)
Query Neighborhood Hits	89	Target Neighborhood Hits	343	Shared Neighborhood Hits	18
SwissProt Accessions	Q14966, Q53R34, Q5XJ05, Q68DP3, Q6P2H2, Q7Z3T7, Q8NF92, Q8TCA1, Q9H2G1, Q9NP37	Gene names	ZNF638, NP220, ZFML
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein) (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL tumor antigen se33-1).

K1H2_MOUSE
θ value	1.06291 (rank : 20)	NC score	0.016895 (rank : 70)
Query Neighborhood Hits	89	Target Neighborhood Hits	446	Shared Neighborhood Hits	18
SwissProt Accessions	Q62168	Gene names	Krtha2, Hka2, Krt1-2
Domain Architecture
Description	Keratin, type I cuticular Ha2 (Hair keratin, type I Ha2).

VDP_MOUSE
θ value	1.06291 (rank : 21)	NC score	0.051515 (rank : 22)
Query Neighborhood Hits	89	Target Neighborhood Hits	469	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z1Z0, Q3T9L9, Q3TH58, Q3U1C7, Q3UMW6, Q91WE7, Q99JZ5	Gene names	Vdp
Domain Architecture	No domain graphic available
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

ABCA4_MOUSE
θ value	1.38821 (rank : 22)	NC score	0.010478 (rank : 79)
Query Neighborhood Hits	89	Target Neighborhood Hits	126	Shared Neighborhood Hits	2
SwissProt Accessions	O35600	Gene names	Abca4, Abcr
Domain Architecture
Description	Retinal-specific ATP-binding cassette transporter (ATP-binding cassette sub-family A member 4) (RIM ABC transporter) (RIM protein) (RmP).

HMMR_MOUSE
θ value	1.38821 (rank : 23)	NC score	0.030522 (rank : 43)
Query Neighborhood Hits	89	Target Neighborhood Hits	1178	Shared Neighborhood Hits	32
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

SMG5_HUMAN
θ value	1.38821 (rank : 24)	NC score	0.034487 (rank : 39)
Query Neighborhood Hits	89	Target Neighborhood Hits	180	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UPR3, Q5QJE7, Q8IXC0, Q8IY09, Q96IJ7	Gene names	SMG5, EST1B, KIAA1089
Domain Architecture	No domain graphic available
Description	Protein SMG5 (SMG-5 homolog) (EST1-like protein B) (LPTS-interacting protein) (LPTS-RP1).

VDP_HUMAN
θ value	1.38821 (rank : 25)	NC score	0.048665 (rank : 24)
Query Neighborhood Hits	89	Target Neighborhood Hits	645	Shared Neighborhood Hits	25
SwissProt Accessions	O60763	Gene names	VDP
Domain Architecture
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

CTDP1_HUMAN
θ value	1.81305 (rank : 26)	NC score	0.034786 (rank : 37)
Query Neighborhood Hits	89	Target Neighborhood Hits	416	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

MATR3_HUMAN
θ value	1.81305 (rank : 27)	NC score	0.059854 (rank : 16)
Query Neighborhood Hits	89	Target Neighborhood Hits	325	Shared Neighborhood Hits	19
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

NSBP1_MOUSE
θ value	1.81305 (rank : 28)	NC score	0.069782 (rank : 9)
Query Neighborhood Hits	89	Target Neighborhood Hits	681	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

ZN516_HUMAN
θ value	1.81305 (rank : 29)	NC score	0.009963 (rank : 81)
Query Neighborhood Hits	89	Target Neighborhood Hits	854	Shared Neighborhood Hits	15
SwissProt Accessions	Q92618	Gene names	ZNF516, KIAA0222
Domain Architecture	No domain graphic available
Description	Zinc finger protein 516.

ZN598_MOUSE
θ value	1.81305 (rank : 30)	NC score	0.026684 (rank : 50)
Query Neighborhood Hits	89	Target Neighborhood Hits	255	Shared Neighborhood Hits	9
SwissProt Accessions	Q80YR4, Q6KAT0, Q8R3S1	Gene names	Znf598, Zfp598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

ATBF1_MOUSE
θ value	2.36792 (rank : 31)	NC score	0.019022 (rank : 65)
Query Neighborhood Hits	89	Target Neighborhood Hits	1841	Shared Neighborhood Hits	37
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

CPSF2_HUMAN
θ value	2.36792 (rank : 32)	NC score	0.032192 (rank : 40)
Query Neighborhood Hits	89	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q9P2I0, Q6NSJ1, Q9H3W7	Gene names	CPSF2, CPSF100, KIAA1367
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 100 kDa subunit (CPSF 100 kDa subunit).

HMMR_HUMAN
θ value	2.36792 (rank : 33)	NC score	0.030600 (rank : 42)
Query Neighborhood Hits	89	Target Neighborhood Hits	1082	Shared Neighborhood Hits	29
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

RBY1A_HUMAN
θ value	2.36792 (rank : 34)	NC score	0.035348 (rank : 35)
Query Neighborhood Hits	89	Target Neighborhood Hits	245	Shared Neighborhood Hits	10
SwissProt Accessions	Q15414, Q15377, Q8NHR0	Gene names	RBMY1A1, RBM1, YRRM1
Domain Architecture
Description	RNA-binding motif protein, Y chromosome, family 1 member A1 (RNA- binding motif protein 1).

ZN335_HUMAN
θ value	2.36792 (rank : 35)	NC score	0.005998 (rank : 88)
Query Neighborhood Hits	89	Target Neighborhood Hits	973	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H4Z2, Q9H684	Gene names	ZNF335
Domain Architecture	No domain graphic available
Description	Zinc finger protein 335.

GBP1_MOUSE
θ value	3.0926 (rank : 36)	NC score	0.021135 (rank : 61)
Query Neighborhood Hits	89	Target Neighborhood Hits	302	Shared Neighborhood Hits	11
SwissProt Accessions	Q01514	Gene names	Gbp1, Gbp-1, Mag-1, Mpa1
Domain Architecture
Description	Interferon-induced guanylate-binding protein 1 (GTP-binding protein 1) (Guanine nucleotide-binding protein 1) (GBP-1) (mGBP1) (mGBP-1) (Interferon-gamma-inducible protein MAG-1).

LRFN5_MOUSE
θ value	3.0926 (rank : 37)	NC score	0.006936 (rank : 87)
Query Neighborhood Hits	89	Target Neighborhood Hits	472	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BXA0, Q8BJH4, Q8BZL0	Gene names	Lrfn5
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

PHLB2_MOUSE
θ value	3.0926 (rank : 38)	NC score	0.040783 (rank : 30)
Query Neighborhood Hits	89	Target Neighborhood Hits	1016	Shared Neighborhood Hits	27
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

RBP56_HUMAN
θ value	3.0926 (rank : 39)	NC score	0.058029 (rank : 18)
Query Neighborhood Hits	89	Target Neighborhood Hits	157	Shared Neighborhood Hits	9
SwissProt Accessions	Q92804, Q92751	Gene names	TAF15, RBP56, TAF2N
Domain Architecture
Description	TATA-binding protein-associated factor 2N (RNA-binding protein 56) (TAFII68) (TAF(II)68).

SRCA_MOUSE
θ value	3.0926 (rank : 40)	NC score	0.040519 (rank : 31)
Query Neighborhood Hits	89	Target Neighborhood Hits	212	Shared Neighborhood Hits	21
SwissProt Accessions	Q7TQ48, Q8BS43	Gene names	Srl, Sar
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

TCF8_HUMAN
θ value	3.0926 (rank : 41)	NC score	0.009157 (rank : 82)
Query Neighborhood Hits	89	Target Neighborhood Hits	1057	Shared Neighborhood Hits	25
SwissProt Accessions	P37275, Q12924, Q13800	Gene names	TCF8, AREB6
Domain Architecture
Description	Transcription factor 8 (NIL-2-A zinc finger protein) (Negative regulator of IL2).

CASC3_HUMAN
θ value	4.03905 (rank : 42)	NC score	0.032002 (rank : 41)
Query Neighborhood Hits	89	Target Neighborhood Hits	204	Shared Neighborhood Hits	19
SwissProt Accessions	O15234	Gene names	CASC3, MLN51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein) (Metastatic lymph node protein 51) (Protein MLN 51) (Protein barentsz) (Btz).

GOGB1_HUMAN
θ value	4.03905 (rank : 43)	NC score	0.024388 (rank : 53)
Query Neighborhood Hits	89	Target Neighborhood Hits	2297	Shared Neighborhood Hits	44
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

GP176_MOUSE
θ value	4.03905 (rank : 44)	NC score	0.012779 (rank : 74)
Query Neighborhood Hits	89	Target Neighborhood Hits	539	Shared Neighborhood Hits	3
SwissProt Accessions	Q80WT4, Q80UC4	Gene names	Gpr176, Agr9, Gm1012
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 176 (G-protein coupled receptor AGR9).

MLL3_MOUSE
θ value	4.03905 (rank : 45)	NC score	0.012666 (rank : 75)
Query Neighborhood Hits	89	Target Neighborhood Hits	1399	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

ASPM_HUMAN
θ value	5.27518 (rank : 46)	NC score	0.017618 (rank : 67)
Query Neighborhood Hits	89	Target Neighborhood Hits	197	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IZT6, Q86UX4, Q8IUL2, Q8IZJ7, Q8IZJ8, Q8IZJ9, Q8N4D1, Q9NVS1, Q9NVT6	Gene names	ASPM, MCPH5
Domain Architecture
Description	Abnormal spindle-like microcephaly-associated protein (Abnormal spindle protein homolog) (Asp homolog).

CHM4C_MOUSE
θ value	5.27518 (rank : 47)	NC score	0.022967 (rank : 55)
Query Neighborhood Hits	89	Target Neighborhood Hits	65	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D7F7, Q3TVD7, Q9CWH8	Gene names	Chmp4c
Domain Architecture	No domain graphic available
Description	Charged multivesicular body protein 4c (Chromatin-modifying protein 4c) (CHMP4c).

CPSF2_MOUSE
θ value	5.27518 (rank : 48)	NC score	0.028885 (rank : 46)
Query Neighborhood Hits	89	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	O35218	Gene names	Cpsf2, Cpsf100, Mcpsf
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 100 kDa subunit (CPSF 100 kDa subunit).

IEX1_HUMAN
θ value	5.27518 (rank : 49)	NC score	0.024442 (rank : 52)
Query Neighborhood Hits	89	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	P46695, Q92691, Q93044	Gene names	IER3, DIF2, IEX1, PRG1
Domain Architecture	No domain graphic available
Description	Radiation-inducible immediate-early gene IEX-1 (Immediate early protein GLY96) (Immediate early response 3 protein) (PACAP-responsive gene 1 protein) (Protein PRG1) (Differentiation-dependent gene 2 protein) (Protein DIF-2).

IWS1_HUMAN
θ value	5.27518 (rank : 50)	NC score	0.047338 (rank : 25)
Query Neighborhood Hits	89	Target Neighborhood Hits	1241	Shared Neighborhood Hits	34
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PEPL_MOUSE
θ value	5.27518 (rank : 51)	NC score	0.019365 (rank : 63)
Query Neighborhood Hits	89	Target Neighborhood Hits	1105	Shared Neighborhood Hits	27
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

RB6I2_MOUSE
θ value	5.27518 (rank : 52)	NC score	0.022701 (rank : 56)
Query Neighborhood Hits	89	Target Neighborhood Hits	1433	Shared Neighborhood Hits	28
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

ROCK2_MOUSE
θ value	5.27518 (rank : 53)	NC score	0.007898 (rank : 84)
Query Neighborhood Hits	89	Target Neighborhood Hits	2072	Shared Neighborhood Hits	28
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

TGON2_HUMAN
θ value	5.27518 (rank : 54)	NC score	0.034640 (rank : 38)
Query Neighborhood Hits	89	Target Neighborhood Hits	1037	Shared Neighborhood Hits	28
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TTF2_MOUSE
θ value	5.27518 (rank : 55)	NC score	0.011251 (rank : 78)
Query Neighborhood Hits	89	Target Neighborhood Hits	364	Shared Neighborhood Hits	11
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

XRCC1_MOUSE
θ value	5.27518 (rank : 56)	NC score	0.035285 (rank : 36)
Query Neighborhood Hits	89	Target Neighborhood Hits	242	Shared Neighborhood Hits	16
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

ZEP2_MOUSE
θ value	5.27518 (rank : 57)	NC score	0.008256 (rank : 83)
Query Neighborhood Hits	89	Target Neighborhood Hits	964	Shared Neighborhood Hits	17
SwissProt Accessions	Q3UHF7, O55140, Q3UVD4, Q3UVH5	Gene names	Hivep2, Mibp1
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Myc intron-binding protein 1) (MIBP-1).

AKA12_HUMAN
θ value	6.88961 (rank : 58)	NC score	0.039122 (rank : 34)
Query Neighborhood Hits	89	Target Neighborhood Hits	825	Shared Neighborhood Hits	34
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

ARP8_HUMAN
θ value	6.88961 (rank : 59)	NC score	0.018102 (rank : 66)
Query Neighborhood Hits	89	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H981, Q9H663	Gene names	ACTR8
Domain Architecture
Description	Actin-related protein 8.

BRE1B_HUMAN
θ value	6.88961 (rank : 60)	NC score	0.021234 (rank : 60)
Query Neighborhood Hits	89	Target Neighborhood Hits	1040	Shared Neighborhood Hits	27
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

BRE1B_MOUSE
θ value	6.88961 (rank : 61)	NC score	0.021731 (rank : 59)
Query Neighborhood Hits	89	Target Neighborhood Hits	970	Shared Neighborhood Hits	24
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

CE110_HUMAN
θ value	6.88961 (rank : 62)	NC score	0.024908 (rank : 51)
Query Neighborhood Hits	89	Target Neighborhood Hits	197	Shared Neighborhood Hits	12
SwissProt Accessions	O43303, O43335, Q68DV9, Q8NE13	Gene names	CEP110, CP110, KIAA0419
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 110 kDa (Cep110 protein).

CEL_HUMAN
θ value	6.88961 (rank : 63)	NC score	0.010121 (rank : 80)
Query Neighborhood Hits	89	Target Neighborhood Hits	896	Shared Neighborhood Hits	12
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CJ118_HUMAN
θ value	6.88961 (rank : 64)	NC score	0.022236 (rank : 58)
Query Neighborhood Hits	89	Target Neighborhood Hits	937	Shared Neighborhood Hits	24
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

FETA_HUMAN
θ value	6.88961 (rank : 65)	NC score	0.014832 (rank : 73)
Query Neighborhood Hits	89	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	P02771	Gene names	AFP
Domain Architecture
Description	Alpha-fetoprotein precursor (Alpha-fetoglobulin) (Alpha-1- fetoprotein).

HA1T_MOUSE
θ value	6.88961 (rank : 66)	NC score	0.001250 (rank : 95)
Query Neighborhood Hits	89	Target Neighborhood Hits	215	Shared Neighborhood Hits	2
SwissProt Accessions	P14432, Q31194, Q31203	Gene names	H2-T3
Domain Architecture
Description	H-2 class I histocompatibility antigen, TLA(B) alpha chain precursor (MHC thymus leukemia antigen).

HTSF1_MOUSE
θ value	6.88961 (rank : 67)	NC score	0.045640 (rank : 26)
Query Neighborhood Hits	89	Target Neighborhood Hits	425	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

LY10_HUMAN
θ value	6.88961 (rank : 68)	NC score	0.012282 (rank : 76)
Query Neighborhood Hits	89	Target Neighborhood Hits	151	Shared Neighborhood Hits	9
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

MBB1A_HUMAN
θ value	6.88961 (rank : 69)	NC score	0.019251 (rank : 64)
Query Neighborhood Hits	89	Target Neighborhood Hits	665	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

NCOA5_MOUSE
θ value	6.88961 (rank : 70)	NC score	0.023626 (rank : 54)
Query Neighborhood Hits	89	Target Neighborhood Hits	87	Shared Neighborhood Hits	4
SwissProt Accessions	Q91W39	Gene names	Ncoa5
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 5 (NCoA-5) (Coactivator independent of AF-2) (CIA).

PCLO_MOUSE
θ value	6.88961 (rank : 71)	NC score	0.011885 (rank : 77)
Query Neighborhood Hits	89	Target Neighborhood Hits	2275	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

ROA3_MOUSE
θ value	6.88961 (rank : 72)	NC score	0.027049 (rank : 49)
Query Neighborhood Hits	89	Target Neighborhood Hits	199	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BG05, Q8BHF8	Gene names	Hnrpa3, Hnrnpa3
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein A3 (hnRNP A3).

RX_MOUSE
θ value	6.88961 (rank : 73)	NC score	0.003501 (rank : 92)
Query Neighborhood Hits	89	Target Neighborhood Hits	429	Shared Neighborhood Hits	3
SwissProt Accessions	O35602, O08748	Gene names	Rax, Rx
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

UBP48_MOUSE
θ value	6.88961 (rank : 74)	NC score	0.007329 (rank : 85)
Query Neighborhood Hits	89	Target Neighborhood Hits	124	Shared Neighborhood Hits	4
SwissProt Accessions	Q3V0C5, Q3TM39, Q571J9, Q8VDJ1	Gene names	Usp48, Kiaa4202
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

ZN638_MOUSE
θ value	6.88961 (rank : 75)	NC score	0.041057 (rank : 29)
Query Neighborhood Hits	89	Target Neighborhood Hits	318	Shared Neighborhood Hits	15
SwissProt Accessions	Q61464, Q6DFV9, Q8C941	Gene names	Znf638, Np220, Zfml
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein).

ARAF_HUMAN
θ value	8.99809 (rank : 76)	NC score	-0.001260 (rank : 96)
Query Neighborhood Hits	89	Target Neighborhood Hits	924	Shared Neighborhood Hits	4
SwissProt Accessions	P10398, P07557, Q5H9B3	Gene names	ARAF, ARAF1, PKS, PKS2
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (A- raf-1) (Proto-oncogene Pks).

ARP8_MOUSE
θ value	8.99809 (rank : 77)	NC score	0.017013 (rank : 69)
Query Neighborhood Hits	89	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R2S9, Q9CYC4	Gene names	Actr8
Domain Architecture
Description	Actin-related protein 8.

BMAL1_MOUSE
θ value	8.99809 (rank : 78)	NC score	0.005479 (rank : 90)
Query Neighborhood Hits	89	Target Neighborhood Hits	121	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

DYNA_HUMAN
θ value	8.99809 (rank : 79)	NC score	0.017026 (rank : 68)
Query Neighborhood Hits	89	Target Neighborhood Hits	1194	Shared Neighborhood Hits	23
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

LIMD1_HUMAN
θ value	8.99809 (rank : 80)	NC score	0.004931 (rank : 91)
Query Neighborhood Hits	89	Target Neighborhood Hits	201	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UGP4, Q9BQQ9, Q9NQ47	Gene names	LIMD1
Domain Architecture
Description	LIM domain-containing protein 1.

MATR3_MOUSE
θ value	8.99809 (rank : 81)	NC score	0.039642 (rank : 33)
Query Neighborhood Hits	89	Target Neighborhood Hits	321	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

NFM_HUMAN
θ value	8.99809 (rank : 82)	NC score	0.028784 (rank : 47)
Query Neighborhood Hits	89	Target Neighborhood Hits	1328	Shared Neighborhood Hits	46
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

NKTR_MOUSE
θ value	8.99809 (rank : 83)	NC score	0.016727 (rank : 71)
Query Neighborhood Hits	89	Target Neighborhood Hits	417	Shared Neighborhood Hits	16
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

RB6I2_HUMAN
θ value	8.99809 (rank : 84)	NC score	0.022535 (rank : 57)
Query Neighborhood Hits	89	Target Neighborhood Hits	1584	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

ROCK2_HUMAN
θ value	8.99809 (rank : 85)	NC score	0.007180 (rank : 86)
Query Neighborhood Hits	89	Target Neighborhood Hits	2073	Shared Neighborhood Hits	27
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

SRBP1_MOUSE
θ value	8.99809 (rank : 86)	NC score	0.027975 (rank : 48)
Query Neighborhood Hits	89	Target Neighborhood Hits	384	Shared Neighborhood Hits	9
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

ZFY1_MOUSE
θ value	8.99809 (rank : 87)	NC score	0.003038 (rank : 94)
Query Neighborhood Hits	89	Target Neighborhood Hits	790	Shared Neighborhood Hits	14
SwissProt Accessions	P10925	Gene names	Zfy1, Zfy-1
Domain Architecture
Description	Zinc finger Y-chromosomal protein 1.

ZFY2_MOUSE
θ value	8.99809 (rank : 88)	NC score	0.003148 (rank : 93)
Query Neighborhood Hits	89	Target Neighborhood Hits	795	Shared Neighborhood Hits	16
SwissProt Accessions	P20662	Gene names	Zfy2, Zfy-2
Domain Architecture
Description	Zinc finger Y-chromosomal protein 2.

ZN462_HUMAN
θ value	8.99809 (rank : 89)	NC score	0.005511 (rank : 89)
Query Neighborhood Hits	89	Target Neighborhood Hits	740	Shared Neighborhood Hits	11
SwissProt Accessions	Q96JM2, Q8N408	Gene names	ZNF462, KIAA1803
Domain Architecture	No domain graphic available
Description	Zinc finger protein 462.

BASP_MOUSE
θ value	θ > 10 (rank : 90)	NC score	0.060141 (rank : 15)
Query Neighborhood Hits	89	Target Neighborhood Hits	260	Shared Neighborhood Hits	18
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

CYLC2_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.050567 (rank : 23)
Query Neighborhood Hits	89	Target Neighborhood Hits	223	Shared Neighborhood Hits	22
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

ERIC1_HUMAN
θ value	θ > 10 (rank : 92)	NC score	0.062646 (rank : 10)
Query Neighborhood Hits	89	Target Neighborhood Hits	364	Shared Neighborhood Hits	19
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

FUS_MOUSE
θ value	θ > 10 (rank : 93)	NC score	0.054564 (rank : 21)
Query Neighborhood Hits	89	Target Neighborhood Hits	154	Shared Neighborhood Hits	9
SwissProt Accessions	P56959	Gene names	Fus
Domain Architecture
Description	RNA-binding protein FUS (Pigpen protein).

LORI_MOUSE
θ value	θ > 10 (rank : 94)	NC score	0.062347 (rank : 11)
Query Neighborhood Hits	89	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

NSBP1_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.058939 (rank : 17)
Query Neighborhood Hits	89	Target Neighborhood Hits	251	Shared Neighborhood Hits	22
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

REN3A_HUMAN
θ value	θ > 10 (rank : 96)	NC score	0.055050 (rank : 20)
Query Neighborhood Hits	89	Target Neighborhood Hits	248	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H1J1, Q5T8C3, Q5T8C9, Q7Z6N3, Q86YK1, Q9BZI8	Gene names	UPF3A, RENT3A, UPF3
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3A (Nonsense mRNA reducing factor 3A) (Up-frameshift suppressor 3 homolog A) (hUpf3).

Hits sorted by NC score

AKP8L_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	89	Target Neighborhood Hits	89	Shared Neighborhood Hits	89
SwissProt Accessions	Q9ULX6, O94792, Q96J58, Q9NRQ0, Q9UGM0	Gene names	AKAP8L, NAKAP95
Domain Architecture
Description	A-kinase anchor protein 8-like (AKAP8-like protein) (Neighbor of A- kinase-anchoring protein 95) (Neighbor of AKAP95) (Homologous to AKAP95 protein) (HA95) (Helicase A-binding protein 95) (HAP95).

AKP8L_MOUSE
NC score	0.985671 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	89	Target Neighborhood Hits	95	Shared Neighborhood Hits	50
SwissProt Accessions	Q9R0L7	Gene names	Akap8l, Nakap95
Domain Architecture
Description	A-kinase anchor protein 8-like (AKAP8-like protein) (Neighbor of A- kinase-anchoring protein 95) (Neighbor of AKAP95).

AKAP8_MOUSE
NC score	0.875568 (rank : 3)	θ value	2.03627e-60 (rank : 4)
Query Neighborhood Hits	89	Target Neighborhood Hits	76	Shared Neighborhood Hits	8
SwissProt Accessions	Q9DBR0, Q9R0L8	Gene names	Akap8, Akap95
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 8 (A-kinase anchor protein 95 kDa) (AKAP 95).

AKAP8_HUMAN
NC score	0.857550 (rank : 4)	θ value	1.15359e-63 (rank : 3)
Query Neighborhood Hits	89	Target Neighborhood Hits	166	Shared Neighborhood Hits	15
SwissProt Accessions	O43823	Gene names	AKAP8, AKAP95
Domain Architecture
Description	A-kinase anchor protein 8 (A-kinase anchor protein 95 kDa) (AKAP 95).

ZN326_HUMAN
NC score	0.743217 (rank : 5)	θ value	1.08979e-29 (rank : 5)
Query Neighborhood Hits	89	Target Neighborhood Hits	90	Shared Neighborhood Hits	13
SwissProt Accessions	Q5BKZ1, Q5VW93, Q5VW94, Q5VW96, Q5VW97, Q6NSA2, Q7Z638, Q7Z6C2	Gene names	ZNF326
Domain Architecture	No domain graphic available
Description	Zinc finger protein 326.

ZN326_MOUSE
NC score	0.738700 (rank : 6)	θ value	3.50572e-28 (rank : 6)
Query Neighborhood Hits	89	Target Neighborhood Hits	117	Shared Neighborhood Hits	19
SwissProt Accessions	O88291, Q8BSJ5, Q8K1X9, Q9CYG9	Gene names	Znf326, Zan75, Zfp326
Domain Architecture	No domain graphic available
Description	Zinc finger protein 326 (Zinc finger protein-associated with nuclear matrix of 75 kDa).

LEO1_MOUSE
NC score	0.082714 (rank : 7)	θ value	0.0961366 (rank : 9)
Query Neighborhood Hits	89	Target Neighborhood Hits	946	Shared Neighborhood Hits	33
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

LEO1_HUMAN
NC score	0.077992 (rank : 8)	θ value	0.0736092 (rank : 8)
Query Neighborhood Hits	89	Target Neighborhood Hits	958	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

NSBP1_MOUSE
NC score	0.069782 (rank : 9)	θ value	1.81305 (rank : 28)
Query Neighborhood Hits	89	Target Neighborhood Hits	681	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

ERIC1_HUMAN
NC score	0.062646 (rank : 10)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	89	Target Neighborhood Hits	364	Shared Neighborhood Hits	19
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

LORI_MOUSE
NC score	0.062347 (rank : 11)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	89	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

IWS1_MOUSE
NC score	0.060661 (rank : 12)	θ value	0.163984 (rank : 11)
Query Neighborhood Hits	89	Target Neighborhood Hits	1258	Shared Neighborhood Hits	33
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

RRBP1_MOUSE
NC score	0.060356 (rank : 13)	θ value	0.00134147 (rank : 7)
Query Neighborhood Hits	89	Target Neighborhood Hits	1650	Shared Neighborhood Hits	47
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

ZN638_HUMAN
NC score	0.060156 (rank : 14)	θ value	0.813845 (rank : 19)
Query Neighborhood Hits	89	Target Neighborhood Hits	343	Shared Neighborhood Hits	18
SwissProt Accessions	Q14966, Q53R34, Q5XJ05, Q68DP3, Q6P2H2, Q7Z3T7, Q8NF92, Q8TCA1, Q9H2G1, Q9NP37	Gene names	ZNF638, NP220, ZFML
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein) (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL tumor antigen se33-1).

BASP_MOUSE
NC score	0.060141 (rank : 15)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	89	Target Neighborhood Hits	260	Shared Neighborhood Hits	18
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

MATR3_HUMAN
NC score	0.059854 (rank : 16)	θ value	1.81305 (rank : 27)
Query Neighborhood Hits	89	Target Neighborhood Hits	325	Shared Neighborhood Hits	19
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

NSBP1_HUMAN
NC score	0.058939 (rank : 17)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	89	Target Neighborhood Hits	251	Shared Neighborhood Hits	22
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

RBP56_HUMAN
NC score	0.058029 (rank : 18)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	89	Target Neighborhood Hits	157	Shared Neighborhood Hits	9
SwissProt Accessions	Q92804, Q92751	Gene names	TAF15, RBP56, TAF2N
Domain Architecture
Description	TATA-binding protein-associated factor 2N (RNA-binding protein 56) (TAFII68) (TAF(II)68).

RRBP1_HUMAN
NC score	0.057731 (rank : 19)	θ value	0.0961366 (rank : 10)
Query Neighborhood Hits	89	Target Neighborhood Hits	1306	Shared Neighborhood Hits	43
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

REN3A_HUMAN
NC score	0.055050 (rank : 20)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	89	Target Neighborhood Hits	248	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H1J1, Q5T8C3, Q5T8C9, Q7Z6N3, Q86YK1, Q9BZI8	Gene names	UPF3A, RENT3A, UPF3
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3A (Nonsense mRNA reducing factor 3A) (Up-frameshift suppressor 3 homolog A) (hUpf3).

FUS_MOUSE
NC score	0.054564 (rank : 21)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	89	Target Neighborhood Hits	154	Shared Neighborhood Hits	9
SwissProt Accessions	P56959	Gene names	Fus
Domain Architecture
Description	RNA-binding protein FUS (Pigpen protein).

VDP_MOUSE
NC score	0.051515 (rank : 22)	θ value	1.06291 (rank : 21)
Query Neighborhood Hits	89	Target Neighborhood Hits	469	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z1Z0, Q3T9L9, Q3TH58, Q3U1C7, Q3UMW6, Q91WE7, Q99JZ5	Gene names	Vdp
Domain Architecture	No domain graphic available
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

CYLC2_HUMAN
NC score	0.050567 (rank : 23)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	89	Target Neighborhood Hits	223	Shared Neighborhood Hits	22
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

VDP_HUMAN
NC score	0.048665 (rank : 24)	θ value	1.38821 (rank : 25)
Query Neighborhood Hits	89	Target Neighborhood Hits	645	Shared Neighborhood Hits	25
SwissProt Accessions	O60763	Gene names	VDP
Domain Architecture
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

IWS1_HUMAN
NC score	0.047338 (rank : 25)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	89	Target Neighborhood Hits	1241	Shared Neighborhood Hits	34
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

HTSF1_MOUSE
NC score	0.045640 (rank : 26)	θ value	6.88961 (rank : 67)
Query Neighborhood Hits	89	Target Neighborhood Hits	425	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

PHLB2_HUMAN
NC score	0.044087 (rank : 27)	θ value	0.47712 (rank : 14)
Query Neighborhood Hits	89	Target Neighborhood Hits	964	Shared Neighborhood Hits	27
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

OXRP_HUMAN
NC score	0.043266 (rank : 28)	θ value	0.47712 (rank : 13)
Query Neighborhood Hits	89	Target Neighborhood Hits	544	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

ZN638_MOUSE
NC score	0.041057 (rank : 29)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	89	Target Neighborhood Hits	318	Shared Neighborhood Hits	15
SwissProt Accessions	Q61464, Q6DFV9, Q8C941	Gene names	Znf638, Np220, Zfml
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein).

PHLB2_MOUSE
NC score	0.040783 (rank : 30)	θ value	3.0926 (rank : 38)
Query Neighborhood Hits	89	Target Neighborhood Hits	1016	Shared Neighborhood Hits	27
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

SRCA_MOUSE
NC score	0.040519 (rank : 31)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	89	Target Neighborhood Hits	212	Shared Neighborhood Hits	21
SwissProt Accessions	Q7TQ48, Q8BS43	Gene names	Srl, Sar
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

MPP8_HUMAN
NC score	0.039907 (rank : 32)	θ value	0.163984 (rank : 12)
Query Neighborhood Hits	89	Target Neighborhood Hits	948	Shared Neighborhood Hits	27
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

MATR3_MOUSE
NC score	0.039642 (rank : 33)	θ value	8.99809 (rank : 81)
Query Neighborhood Hits	89	Target Neighborhood Hits	321	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

AKA12_HUMAN
NC score	0.039122 (rank : 34)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	89	Target Neighborhood Hits	825	Shared Neighborhood Hits	34
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

RBY1A_HUMAN
NC score	0.035348 (rank : 35)	θ value	2.36792 (rank : 34)
Query Neighborhood Hits	89	Target Neighborhood Hits	245	Shared Neighborhood Hits	10
SwissProt Accessions	Q15414, Q15377, Q8NHR0	Gene names	RBMY1A1, RBM1, YRRM1
Domain Architecture
Description	RNA-binding motif protein, Y chromosome, family 1 member A1 (RNA- binding motif protein 1).

XRCC1_MOUSE
NC score	0.035285 (rank : 36)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	89	Target Neighborhood Hits	242	Shared Neighborhood Hits	16
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

CTDP1_HUMAN
NC score	0.034786 (rank : 37)	θ value	1.81305 (rank : 26)
Query Neighborhood Hits	89	Target Neighborhood Hits	416	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

TGON2_HUMAN
NC score	0.034640 (rank : 38)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	89	Target Neighborhood Hits	1037	Shared Neighborhood Hits	28
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

SMG5_HUMAN
NC score	0.034487 (rank : 39)	θ value	1.38821 (rank : 24)
Query Neighborhood Hits	89	Target Neighborhood Hits	180	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UPR3, Q5QJE7, Q8IXC0, Q8IY09, Q96IJ7	Gene names	SMG5, EST1B, KIAA1089
Domain Architecture	No domain graphic available
Description	Protein SMG5 (SMG-5 homolog) (EST1-like protein B) (LPTS-interacting protein) (LPTS-RP1).

CPSF2_HUMAN
NC score	0.032192 (rank : 40)	θ value	2.36792 (rank : 32)
Query Neighborhood Hits	89	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q9P2I0, Q6NSJ1, Q9H3W7	Gene names	CPSF2, CPSF100, KIAA1367
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 100 kDa subunit (CPSF 100 kDa subunit).

CASC3_HUMAN
NC score	0.032002 (rank : 41)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	89	Target Neighborhood Hits	204	Shared Neighborhood Hits	19
SwissProt Accessions	O15234	Gene names	CASC3, MLN51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein) (Metastatic lymph node protein 51) (Protein MLN 51) (Protein barentsz) (Btz).

HMMR_HUMAN
NC score	0.030600 (rank : 42)	θ value	2.36792 (rank : 33)
Query Neighborhood Hits	89	Target Neighborhood Hits	1082	Shared Neighborhood Hits	29
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

HMMR_MOUSE
NC score	0.030522 (rank : 43)	θ value	1.38821 (rank : 23)
Query Neighborhood Hits	89	Target Neighborhood Hits	1178	Shared Neighborhood Hits	32
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

TRIM1_HUMAN
NC score	0.029617 (rank : 44)	θ value	0.62314 (rank : 17)
Query Neighborhood Hits	89	Target Neighborhood Hits	345	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRIM1_MOUSE
NC score	0.029129 (rank : 45)	θ value	0.62314 (rank : 18)
Query Neighborhood Hits	89	Target Neighborhood Hits	361	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

CPSF2_MOUSE
NC score	0.028885 (rank : 46)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	89	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	O35218	Gene names	Cpsf2, Cpsf100, Mcpsf
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 100 kDa subunit (CPSF 100 kDa subunit).

NFM_HUMAN
NC score	0.028784 (rank : 47)	θ value	8.99809 (rank : 82)
Query Neighborhood Hits	89	Target Neighborhood Hits	1328	Shared Neighborhood Hits	46
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

SRBP1_MOUSE
NC score	0.027975 (rank : 48)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	89	Target Neighborhood Hits	384	Shared Neighborhood Hits	9
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

ROA3_MOUSE
NC score	0.027049 (rank : 49)	θ value	6.88961 (rank : 72)
Query Neighborhood Hits	89	Target Neighborhood Hits	199	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BG05, Q8BHF8	Gene names	Hnrpa3, Hnrnpa3
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein A3 (hnRNP A3).

ZN598_MOUSE
NC score	0.026684 (rank : 50)	θ value	1.81305 (rank : 30)
Query Neighborhood Hits	89	Target Neighborhood Hits	255	Shared Neighborhood Hits	9
SwissProt Accessions	Q80YR4, Q6KAT0, Q8R3S1	Gene names	Znf598, Zfp598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

CE110_HUMAN
NC score	0.024908 (rank : 51)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	89	Target Neighborhood Hits	197	Shared Neighborhood Hits	12
SwissProt Accessions	O43303, O43335, Q68DV9, Q8NE13	Gene names	CEP110, CP110, KIAA0419
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 110 kDa (Cep110 protein).

IEX1_HUMAN
NC score	0.024442 (rank : 52)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	89	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	P46695, Q92691, Q93044	Gene names	IER3, DIF2, IEX1, PRG1
Domain Architecture	No domain graphic available
Description	Radiation-inducible immediate-early gene IEX-1 (Immediate early protein GLY96) (Immediate early response 3 protein) (PACAP-responsive gene 1 protein) (Protein PRG1) (Differentiation-dependent gene 2 protein) (Protein DIF-2).

GOGB1_HUMAN
NC score	0.024388 (rank : 53)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	89	Target Neighborhood Hits	2297	Shared Neighborhood Hits	44
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

NCOA5_MOUSE
NC score	0.023626 (rank : 54)	θ value	6.88961 (rank : 70)
Query Neighborhood Hits	89	Target Neighborhood Hits	87	Shared Neighborhood Hits	4
SwissProt Accessions	Q91W39	Gene names	Ncoa5
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 5 (NCoA-5) (Coactivator independent of AF-2) (CIA).

CHM4C_MOUSE
NC score	0.022967 (rank : 55)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	89	Target Neighborhood Hits	65	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D7F7, Q3TVD7, Q9CWH8	Gene names	Chmp4c
Domain Architecture	No domain graphic available
Description	Charged multivesicular body protein 4c (Chromatin-modifying protein 4c) (CHMP4c).

RB6I2_MOUSE
NC score	0.022701 (rank : 56)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	89	Target Neighborhood Hits	1433	Shared Neighborhood Hits	28
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

RB6I2_HUMAN
NC score	0.022535 (rank : 57)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	89	Target Neighborhood Hits	1584	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

CJ118_HUMAN
NC score	0.022236 (rank : 58)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	89	Target Neighborhood Hits	937	Shared Neighborhood Hits	24
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

BRE1B_MOUSE
NC score	0.021731 (rank : 59)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	89	Target Neighborhood Hits	970	Shared Neighborhood Hits	24
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

BRE1B_HUMAN
NC score	0.021234 (rank : 60)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	89	Target Neighborhood Hits	1040	Shared Neighborhood Hits	27
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

GBP1_MOUSE
NC score	0.021135 (rank : 61)	θ value	3.0926 (rank : 36)
Query Neighborhood Hits	89	Target Neighborhood Hits	302	Shared Neighborhood Hits	11
SwissProt Accessions	Q01514	Gene names	Gbp1, Gbp-1, Mag-1, Mpa1
Domain Architecture
Description	Interferon-induced guanylate-binding protein 1 (GTP-binding protein 1) (Guanine nucleotide-binding protein 1) (GBP-1) (mGBP1) (mGBP-1) (Interferon-gamma-inducible protein MAG-1).

COFA1_HUMAN
NC score	0.020932 (rank : 62)	θ value	0.62314 (rank : 15)
Query Neighborhood Hits	89	Target Neighborhood Hits	292	Shared Neighborhood Hits	10
SwissProt Accessions	P39059, Q5T6J4, Q9Y4W4	Gene names	COL15A1
Domain Architecture
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV) (Restin) (Related to endostatin)].

PEPL_MOUSE
NC score	0.019365 (rank : 63)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	89	Target Neighborhood Hits	1105	Shared Neighborhood Hits	27
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

MBB1A_HUMAN
NC score	0.019251 (rank : 64)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	89	Target Neighborhood Hits	665	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

ATBF1_MOUSE
NC score	0.019022 (rank : 65)	θ value	2.36792 (rank : 31)
Query Neighborhood Hits	89	Target Neighborhood Hits	1841	Shared Neighborhood Hits	37
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

ARP8_HUMAN
NC score	0.018102 (rank : 66)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	89	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H981, Q9H663	Gene names	ACTR8
Domain Architecture
Description	Actin-related protein 8.

ASPM_HUMAN
NC score	0.017618 (rank : 67)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	89	Target Neighborhood Hits	197	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IZT6, Q86UX4, Q8IUL2, Q8IZJ7, Q8IZJ8, Q8IZJ9, Q8N4D1, Q9NVS1, Q9NVT6	Gene names	ASPM, MCPH5
Domain Architecture
Description	Abnormal spindle-like microcephaly-associated protein (Abnormal spindle protein homolog) (Asp homolog).

DYNA_HUMAN
NC score	0.017026 (rank : 68)	θ value	8.99809 (rank : 79)
Query Neighborhood Hits	89	Target Neighborhood Hits	1194	Shared Neighborhood Hits	23
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

ARP8_MOUSE
NC score	0.017013 (rank : 69)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	89	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R2S9, Q9CYC4	Gene names	Actr8
Domain Architecture
Description	Actin-related protein 8.

K1H2_MOUSE
NC score	0.016895 (rank : 70)	θ value	1.06291 (rank : 20)
Query Neighborhood Hits	89	Target Neighborhood Hits	446	Shared Neighborhood Hits	18
SwissProt Accessions	Q62168	Gene names	Krtha2, Hka2, Krt1-2
Domain Architecture
Description	Keratin, type I cuticular Ha2 (Hair keratin, type I Ha2).

NKTR_MOUSE
NC score	0.016727 (rank : 71)	θ value	8.99809 (rank : 83)
Query Neighborhood Hits	89	Target Neighborhood Hits	417	Shared Neighborhood Hits	16
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

GP176_HUMAN
NC score	0.015856 (rank : 72)	θ value	0.62314 (rank : 16)
Query Neighborhood Hits	89	Target Neighborhood Hits	522	Shared Neighborhood Hits	3
SwissProt Accessions	Q14439, Q6NXF6	Gene names	GPR176
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 176 (HB-954).

FETA_HUMAN
NC score	0.014832 (rank : 73)	θ value	6.88961 (rank : 65)
Query Neighborhood Hits	89	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	P02771	Gene names	AFP
Domain Architecture
Description	Alpha-fetoprotein precursor (Alpha-fetoglobulin) (Alpha-1- fetoprotein).

GP176_MOUSE
NC score	0.012779 (rank : 74)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	89	Target Neighborhood Hits	539	Shared Neighborhood Hits	3
SwissProt Accessions	Q80WT4, Q80UC4	Gene names	Gpr176, Agr9, Gm1012
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 176 (G-protein coupled receptor AGR9).

MLL3_MOUSE
NC score	0.012666 (rank : 75)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	89	Target Neighborhood Hits	1399	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

LY10_HUMAN
NC score	0.012282 (rank : 76)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	89	Target Neighborhood Hits	151	Shared Neighborhood Hits	9
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

PCLO_MOUSE
NC score	0.011885 (rank : 77)	θ value	6.88961 (rank : 71)
Query Neighborhood Hits	89	Target Neighborhood Hits	2275	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

TTF2_MOUSE
NC score	0.011251 (rank : 78)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	89	Target Neighborhood Hits	364	Shared Neighborhood Hits	11
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

ABCA4_MOUSE
NC score	0.010478 (rank : 79)	θ value	1.38821 (rank : 22)
Query Neighborhood Hits	89	Target Neighborhood Hits	126	Shared Neighborhood Hits	2
SwissProt Accessions	O35600	Gene names	Abca4, Abcr
Domain Architecture
Description	Retinal-specific ATP-binding cassette transporter (ATP-binding cassette sub-family A member 4) (RIM ABC transporter) (RIM protein) (RmP).

CEL_HUMAN
NC score	0.010121 (rank : 80)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	89	Target Neighborhood Hits	896	Shared Neighborhood Hits	12
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

ZN516_HUMAN
NC score	0.009963 (rank : 81)	θ value	1.81305 (rank : 29)
Query Neighborhood Hits	89	Target Neighborhood Hits	854	Shared Neighborhood Hits	15
SwissProt Accessions	Q92618	Gene names	ZNF516, KIAA0222
Domain Architecture	No domain graphic available
Description	Zinc finger protein 516.

TCF8_HUMAN
NC score	0.009157 (rank : 82)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	89	Target Neighborhood Hits	1057	Shared Neighborhood Hits	25
SwissProt Accessions	P37275, Q12924, Q13800	Gene names	TCF8, AREB6
Domain Architecture
Description	Transcription factor 8 (NIL-2-A zinc finger protein) (Negative regulator of IL2).

ZEP2_MOUSE
NC score	0.008256 (rank : 83)	θ value	5.27518 (rank : 57)
Query Neighborhood Hits	89	Target Neighborhood Hits	964	Shared Neighborhood Hits	17
SwissProt Accessions	Q3UHF7, O55140, Q3UVD4, Q3UVH5	Gene names	Hivep2, Mibp1
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Myc intron-binding protein 1) (MIBP-1).

ROCK2_MOUSE
NC score	0.007898 (rank : 84)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	89	Target Neighborhood Hits	2072	Shared Neighborhood Hits	28
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

UBP48_MOUSE
NC score	0.007329 (rank : 85)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	89	Target Neighborhood Hits	124	Shared Neighborhood Hits	4
SwissProt Accessions	Q3V0C5, Q3TM39, Q571J9, Q8VDJ1	Gene names	Usp48, Kiaa4202
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

ROCK2_HUMAN
NC score	0.007180 (rank : 86)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	89	Target Neighborhood Hits	2073	Shared Neighborhood Hits	27
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

LRFN5_MOUSE
NC score	0.006936 (rank : 87)	θ value	3.0926 (rank : 37)
Query Neighborhood Hits	89	Target Neighborhood Hits	472	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BXA0, Q8BJH4, Q8BZL0	Gene names	Lrfn5
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

ZN335_HUMAN
NC score	0.005998 (rank : 88)	θ value	2.36792 (rank : 35)
Query Neighborhood Hits	89	Target Neighborhood Hits	973	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H4Z2, Q9H684	Gene names	ZNF335
Domain Architecture	No domain graphic available
Description	Zinc finger protein 335.

ZN462_HUMAN
NC score	0.005511 (rank : 89)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	89	Target Neighborhood Hits	740	Shared Neighborhood Hits	11
SwissProt Accessions	Q96JM2, Q8N408	Gene names	ZNF462, KIAA1803
Domain Architecture	No domain graphic available
Description	Zinc finger protein 462.

BMAL1_MOUSE
NC score	0.005479 (rank : 90)	θ value	8.99809 (rank : 78)
Query Neighborhood Hits	89	Target Neighborhood Hits	121	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

LIMD1_HUMAN
NC score	0.004931 (rank : 91)	θ value	8.99809 (rank : 80)
Query Neighborhood Hits	89	Target Neighborhood Hits	201	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UGP4, Q9BQQ9, Q9NQ47	Gene names	LIMD1
Domain Architecture
Description	LIM domain-containing protein 1.

RX_MOUSE
NC score	0.003501 (rank : 92)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	89	Target Neighborhood Hits	429	Shared Neighborhood Hits	3
SwissProt Accessions	O35602, O08748	Gene names	Rax, Rx
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

ZFY2_MOUSE
NC score	0.003148 (rank : 93)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	89	Target Neighborhood Hits	795	Shared Neighborhood Hits	16
SwissProt Accessions	P20662	Gene names	Zfy2, Zfy-2
Domain Architecture
Description	Zinc finger Y-chromosomal protein 2.

ZFY1_MOUSE
NC score	0.003038 (rank : 94)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	89	Target Neighborhood Hits	790	Shared Neighborhood Hits	14
SwissProt Accessions	P10925	Gene names	Zfy1, Zfy-1
Domain Architecture
Description	Zinc finger Y-chromosomal protein 1.

HA1T_MOUSE
NC score	0.001250 (rank : 95)	θ value	6.88961 (rank : 66)
Query Neighborhood Hits	89	Target Neighborhood Hits	215	Shared Neighborhood Hits	2
SwissProt Accessions	P14432, Q31194, Q31203	Gene names	H2-T3
Domain Architecture
Description	H-2 class I histocompatibility antigen, TLA(B) alpha chain precursor (MHC thymus leukemia antigen).

ARAF_HUMAN
NC score	-0.001260 (rank : 96)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	89	Target Neighborhood Hits	924	Shared Neighborhood Hits	4
SwissProt Accessions	P10398, P07557, Q5H9B3	Gene names	ARAF, ARAF1, PKS, PKS2
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (A- raf-1) (Proto-oncogene Pks).