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Network neighborhood for query Sequence : MAD4_HUMAN

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MAD4_HUMAN
SwissProt Accessions	Q14582, Q5TZX4	Gene names	MXD4, MAD4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MAD4_HUMAN
θ value	3.66817e-102 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	94	Target Neighborhood Hits	94	Shared Neighborhood Hits	94
SwissProt Accessions	Q14582, Q5TZX4	Gene names	MXD4, MAD4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MAD4_MOUSE
θ value	1.22395e-89 (rank : 2)	NC score	0.974956 (rank : 2)
Query Neighborhood Hits	94	Target Neighborhood Hits	65	Shared Neighborhood Hits	54
SwissProt Accessions	Q60948	Gene names	Mxd4, Mad4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MXI1_MOUSE
θ value	1.05066e-40 (rank : 3)	NC score	0.920874 (rank : 4)
Query Neighborhood Hits	94	Target Neighborhood Hits	109	Shared Neighborhood Hits	45
SwissProt Accessions	P50540	Gene names	Mxi1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MXI1_HUMAN
θ value	9.83387e-39 (rank : 4)	NC score	0.924610 (rank : 3)
Query Neighborhood Hits	94	Target Neighborhood Hits	76	Shared Neighborhood Hits	39
SwissProt Accessions	P50539, Q15887	Gene names	MXI1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MAD1_HUMAN
θ value	6.37413e-38 (rank : 5)	NC score	0.905169 (rank : 6)
Query Neighborhood Hits	94	Target Neighborhood Hits	68	Shared Neighborhood Hits	35
SwissProt Accessions	Q05195	Gene names	MXD1, MAD
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

MAD1_MOUSE
θ value	1.85459e-37 (rank : 6)	NC score	0.907110 (rank : 5)
Query Neighborhood Hits	94	Target Neighborhood Hits	75	Shared Neighborhood Hits	40
SwissProt Accessions	P50538, Q60798, Q61825	Gene names	Mxd1, Mad, Mad1
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

MAD3_HUMAN
θ value	5.06226e-27 (rank : 7)	NC score	0.895203 (rank : 7)
Query Neighborhood Hits	94	Target Neighborhood Hits	92	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BW11, Q53HK1, Q7Z4Y0, Q8NDJ7, Q96ME3	Gene names	MXD3, MAD3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3) (Myx).

MAD3_MOUSE
θ value	1.12775e-26 (rank : 8)	NC score	0.889295 (rank : 8)
Query Neighborhood Hits	94	Target Neighborhood Hits	94	Shared Neighborhood Hits	36
SwissProt Accessions	Q80US8, Q60947	Gene names	Mxd3, Mad3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3).

MNT_MOUSE
θ value	5.44631e-05 (rank : 9)	NC score	0.442314 (rank : 9)
Query Neighborhood Hits	94	Target Neighborhood Hits	432	Shared Neighborhood Hits	44
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MNT_HUMAN
θ value	0.000121331 (rank : 10)	NC score	0.425144 (rank : 10)
Query Neighborhood Hits	94	Target Neighborhood Hits	496	Shared Neighborhood Hits	47
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MYC_HUMAN
θ value	0.000270298 (rank : 11)	NC score	0.357277 (rank : 12)
Query Neighborhood Hits	94	Target Neighborhood Hits	146	Shared Neighborhood Hits	41
SwissProt Accessions	P01106, P01107, Q14026	Gene names	MYC
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

MYC_MOUSE
θ value	0.00035302 (rank : 12)	NC score	0.359403 (rank : 11)
Query Neighborhood Hits	94	Target Neighborhood Hits	125	Shared Neighborhood Hits	35
SwissProt Accessions	P01108, P70247, Q3UM70, Q61422	Gene names	Myc
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

TFE3_HUMAN
θ value	0.00035302 (rank : 13)	NC score	0.312530 (rank : 17)
Query Neighborhood Hits	94	Target Neighborhood Hits	190	Shared Neighborhood Hits	50
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

MITF_HUMAN
θ value	0.00228821 (rank : 14)	NC score	0.303060 (rank : 19)
Query Neighborhood Hits	94	Target Neighborhood Hits	113	Shared Neighborhood Hits	44
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

RPC5_HUMAN
θ value	0.00228821 (rank : 15)	NC score	0.127382 (rank : 45)
Query Neighborhood Hits	94	Target Neighborhood Hits	36	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NVU0, Q9BWF7, Q9H8W8, Q9H907, Q9P276	Gene names	POLR3E, KIAA1452
Domain Architecture
Description	DNA-directed RNA polymerases III 80 kDa polypeptide (EC 2.7.7.6) (RNA polymerase III subunit 5) (RPC5).

USF2_HUMAN
θ value	0.00228821 (rank : 16)	NC score	0.353202 (rank : 13)
Query Neighborhood Hits	94	Target Neighborhood Hits	155	Shared Neighborhood Hits	49
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

USF2_MOUSE
θ value	0.00228821 (rank : 17)	NC score	0.351793 (rank : 14)
Query Neighborhood Hits	94	Target Neighborhood Hits	173	Shared Neighborhood Hits	49
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

MITF_MOUSE
θ value	0.00298849 (rank : 18)	NC score	0.294963 (rank : 20)
Query Neighborhood Hits	94	Target Neighborhood Hits	115	Shared Neighborhood Hits	45
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

TFEB_MOUSE
θ value	0.00390308 (rank : 19)	NC score	0.267924 (rank : 27)
Query Neighborhood Hits	94	Target Neighborhood Hits	119	Shared Neighborhood Hits	41
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

MYCL2_HUMAN
θ value	0.00509761 (rank : 20)	NC score	0.308661 (rank : 18)
Query Neighborhood Hits	94	Target Neighborhood Hits	63	Shared Neighborhood Hits	26
SwissProt Accessions	P12525	Gene names	MYCL2
Domain Architecture
Description	L-myc-2 protein.

MYCN_HUMAN
θ value	0.00509761 (rank : 21)	NC score	0.289872 (rank : 23)
Query Neighborhood Hits	94	Target Neighborhood Hits	127	Shared Neighborhood Hits	36
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.

SRBP1_MOUSE
θ value	0.00509761 (rank : 22)	NC score	0.185646 (rank : 32)
Query Neighborhood Hits	94	Target Neighborhood Hits	384	Shared Neighborhood Hits	42
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

TFEB_HUMAN
θ value	0.00509761 (rank : 23)	NC score	0.268062 (rank : 26)
Query Neighborhood Hits	94	Target Neighborhood Hits	111	Shared Neighborhood Hits	42
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

SRBP2_HUMAN
θ value	0.00665767 (rank : 24)	NC score	0.216620 (rank : 30)
Query Neighborhood Hits	94	Target Neighborhood Hits	133	Shared Neighborhood Hits	37
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

USF1_HUMAN
θ value	0.00665767 (rank : 25)	NC score	0.340362 (rank : 16)
Query Neighborhood Hits	94	Target Neighborhood Hits	70	Shared Neighborhood Hits	45
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF1_MOUSE
θ value	0.00665767 (rank : 26)	NC score	0.341337 (rank : 15)
Query Neighborhood Hits	94	Target Neighborhood Hits	71	Shared Neighborhood Hits	45
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

MYCN_MOUSE
θ value	0.0113563 (rank : 27)	NC score	0.290986 (rank : 22)
Query Neighborhood Hits	94	Target Neighborhood Hits	125	Shared Neighborhood Hits	38
SwissProt Accessions	P03966, Q61978	Gene names	Mycn, Nmyc, Nmyc1
Domain Architecture
Description	N-myc proto-oncogene protein.

MYCL1_HUMAN
θ value	0.0252991 (rank : 28)	NC score	0.291756 (rank : 21)
Query Neighborhood Hits	94	Target Neighborhood Hits	146	Shared Neighborhood Hits	39
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

HOOK1_HUMAN
θ value	0.0330416 (rank : 29)	NC score	0.045022 (rank : 67)
Query Neighborhood Hits	94	Target Neighborhood Hits	942	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

BMAL1_HUMAN
θ value	0.0431538 (rank : 30)	NC score	0.137252 (rank : 40)
Query Neighborhood Hits	94	Target Neighborhood Hits	115	Shared Neighborhood Hits	37
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

BMAL1_MOUSE
θ value	0.0563607 (rank : 31)	NC score	0.136181 (rank : 41)
Query Neighborhood Hits	94	Target Neighborhood Hits	121	Shared Neighborhood Hits	37
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

MYCL1_MOUSE
θ value	0.0563607 (rank : 32)	NC score	0.287153 (rank : 24)
Query Neighborhood Hits	94	Target Neighborhood Hits	123	Shared Neighborhood Hits	39
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYCS_MOUSE
θ value	0.125558 (rank : 33)	NC score	0.250475 (rank : 29)
Query Neighborhood Hits	94	Target Neighborhood Hits	83	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z304	Gene names	Mycs
Domain Architecture
Description	Protein S-myc.

ARNT_HUMAN
θ value	0.163984 (rank : 34)	NC score	0.139403 (rank : 39)
Query Neighborhood Hits	94	Target Neighborhood Hits	109	Shared Neighborhood Hits	38
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

ARNT_MOUSE
θ value	0.163984 (rank : 35)	NC score	0.131409 (rank : 43)
Query Neighborhood Hits	94	Target Neighborhood Hits	213	Shared Neighborhood Hits	39
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

ARNT2_HUMAN
θ value	0.279714 (rank : 36)	NC score	0.123502 (rank : 47)
Query Neighborhood Hits	94	Target Neighborhood Hits	109	Shared Neighborhood Hits	34
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT2_MOUSE
θ value	0.279714 (rank : 37)	NC score	0.123879 (rank : 46)
Query Neighborhood Hits	94	Target Neighborhood Hits	115	Shared Neighborhood Hits	34
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

CCDC6_HUMAN
θ value	0.279714 (rank : 38)	NC score	0.054134 (rank : 64)
Query Neighborhood Hits	94	Target Neighborhood Hits	723	Shared Neighborhood Hits	35
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

ENAH_MOUSE
θ value	0.279714 (rank : 39)	NC score	0.027266 (rank : 86)
Query Neighborhood Hits	94	Target Neighborhood Hits	919	Shared Neighborhood Hits	26
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

HES1_HUMAN
θ value	0.365318 (rank : 40)	NC score	0.148930 (rank : 36)
Query Neighborhood Hits	94	Target Neighborhood Hits	76	Shared Neighborhood Hits	28
SwissProt Accessions	Q14469	Gene names	HES1, HL, HRY
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1) (Hairy- like) (HHL) (Hairy homolog).

HES1_MOUSE
θ value	0.365318 (rank : 41)	NC score	0.149368 (rank : 35)
Query Neighborhood Hits	94	Target Neighborhood Hits	78	Shared Neighborhood Hits	29
SwissProt Accessions	P35428	Gene names	Hes1, Hes-1
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1).

HOOK1_MOUSE
θ value	0.365318 (rank : 42)	NC score	0.040977 (rank : 70)
Query Neighborhood Hits	94	Target Neighborhood Hits	910	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

NONO_HUMAN
θ value	0.47712 (rank : 43)	NC score	0.042893 (rank : 68)
Query Neighborhood Hits	94	Target Neighborhood Hits	441	Shared Neighborhood Hits	17
SwissProt Accessions	Q15233, O00201, P30807, Q12786, Q9BQC5	Gene names	NONO, NRB54
Domain Architecture
Description	Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding p52/p100 complex, 52 kDa subunit).

NONO_MOUSE
θ value	0.47712 (rank : 44)	NC score	0.042803 (rank : 69)
Query Neighborhood Hits	94	Target Neighborhood Hits	444	Shared Neighborhood Hits	17
SwissProt Accessions	Q99K48, Q63887, Q9CYQ4, Q9DBP2	Gene names	Nono
Domain Architecture	No domain graphic available
Description	Non-POU domain-containing octamer-binding protein (NonO protein).

GBP1_HUMAN
θ value	0.62314 (rank : 45)	NC score	0.029973 (rank : 81)
Query Neighborhood Hits	94	Target Neighborhood Hits	339	Shared Neighborhood Hits	21
SwissProt Accessions	P32455	Gene names	GBP1
Domain Architecture
Description	Interferon-induced guanylate-binding protein 1 (GTP-binding protein 1) (Guanine nucleotide-binding protein 1) (GBP-1) (HuGBP-1).

KTN1_HUMAN
θ value	0.62314 (rank : 46)	NC score	0.031711 (rank : 79)
Query Neighborhood Hits	94	Target Neighborhood Hits	1197	Shared Neighborhood Hits	35
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

TRHY_HUMAN
θ value	0.62314 (rank : 47)	NC score	0.030975 (rank : 80)
Query Neighborhood Hits	94	Target Neighborhood Hits	1385	Shared Neighborhood Hits	36
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

BHLH2_MOUSE
θ value	0.813845 (rank : 48)	NC score	0.146579 (rank : 38)
Query Neighborhood Hits	94	Target Neighborhood Hits	70	Shared Neighborhood Hits	35
SwissProt Accessions	O35185, P97289	Gene names	Bhlhb2, Clast5, Stra13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Stimulated with retinoic acid 13) (E47 interaction protein 1) (eipl).

MOES_MOUSE
θ value	1.06291 (rank : 49)	NC score	0.021763 (rank : 94)
Query Neighborhood Hits	94	Target Neighborhood Hits	923	Shared Neighborhood Hits	27
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

HES4_HUMAN
θ value	1.38821 (rank : 50)	NC score	0.117909 (rank : 48)
Query Neighborhood Hits	94	Target Neighborhood Hits	58	Shared Neighborhood Hits	30
SwissProt Accessions	Q9HCC6	Gene names	HES4
Domain Architecture
Description	Transcription factor HES-4 (Hairy and enhancer of split 4) (bHLH factor Hes4).

TRIPB_HUMAN
θ value	1.38821 (rank : 51)	NC score	0.034343 (rank : 76)
Query Neighborhood Hits	94	Target Neighborhood Hits	1587	Shared Neighborhood Hits	44
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

ARI1_MOUSE
θ value	1.81305 (rank : 52)	NC score	0.016628 (rank : 101)
Query Neighborhood Hits	94	Target Neighborhood Hits	71	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z1K5, Q6PF92	Gene names	Arih1, Ari, Ubch7bp, Uip77
Domain Architecture	No domain graphic available
Description	Protein ariadne-1 homolog (ARI-1) (Ubiquitin-conjugating enzyme E2- binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein 77).

MOES_HUMAN
θ value	1.81305 (rank : 53)	NC score	0.023663 (rank : 91)
Query Neighborhood Hits	94	Target Neighborhood Hits	892	Shared Neighborhood Hits	30
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

NDE1_MOUSE
θ value	1.81305 (rank : 54)	NC score	0.036132 (rank : 73)
Query Neighborhood Hits	94	Target Neighborhood Hits	602	Shared Neighborhood Hits	28
SwissProt Accessions	Q9CZA6, Q3UBS6, Q3UIC1, Q9ERR0	Gene names	Nde1, Nude
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE) (mNudE).

AN30A_HUMAN
θ value	2.36792 (rank : 55)	NC score	0.023226 (rank : 93)
Query Neighborhood Hits	94	Target Neighborhood Hits	1119	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

BHLH2_HUMAN
θ value	2.36792 (rank : 56)	NC score	0.134979 (rank : 42)
Query Neighborhood Hits	94	Target Neighborhood Hits	80	Shared Neighborhood Hits	37
SwissProt Accessions	O14503, Q96TD3	Gene names	BHLHB2, DEC1, SHARP2, STRA13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Differentially expressed in chondrocytes protein 1) (DEC1) (Enhancer-of-split and hairy-related protein 2) (SHARP-2) (Stimulated with retinoic acid 13).

EEA1_HUMAN
θ value	2.36792 (rank : 57)	NC score	0.026227 (rank : 87)
Query Neighborhood Hits	94	Target Neighborhood Hits	1796	Shared Neighborhood Hits	40
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

EEA1_MOUSE
θ value	2.36792 (rank : 58)	NC score	0.028060 (rank : 84)
Query Neighborhood Hits	94	Target Neighborhood Hits	1637	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

MINK1_HUMAN
θ value	2.36792 (rank : 59)	NC score	0.005195 (rank : 109)
Query Neighborhood Hits	94	Target Neighborhood Hits	1477	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MINK1_MOUSE
θ value	2.36792 (rank : 60)	NC score	0.005210 (rank : 108)
Query Neighborhood Hits	94	Target Neighborhood Hits	1451	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

TCFL5_HUMAN
θ value	2.36792 (rank : 61)	NC score	0.195729 (rank : 31)
Query Neighborhood Hits	94	Target Neighborhood Hits	43	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UL49, O94771, Q9BYW0	Gene names	TCFL5, CHA, E2BP1
Domain Architecture	No domain graphic available
Description	Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).

XE7_HUMAN
θ value	2.36792 (rank : 62)	NC score	0.036792 (rank : 72)
Query Neighborhood Hits	94	Target Neighborhood Hits	738	Shared Neighborhood Hits	32
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

BAZ1A_HUMAN
θ value	3.0926 (rank : 63)	NC score	0.016070 (rank : 102)
Query Neighborhood Hits	94	Target Neighborhood Hits	693	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

CING_MOUSE
θ value	3.0926 (rank : 64)	NC score	0.035403 (rank : 74)
Query Neighborhood Hits	94	Target Neighborhood Hits	1432	Shared Neighborhood Hits	42
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

INCE_MOUSE
θ value	3.0926 (rank : 65)	NC score	0.023447 (rank : 92)
Query Neighborhood Hits	94	Target Neighborhood Hits	903	Shared Neighborhood Hits	30
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

RPC5_MOUSE
θ value	3.0926 (rank : 66)	NC score	0.070138 (rank : 56)
Query Neighborhood Hits	94	Target Neighborhood Hits	40	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CZT4, Q8CI35, Q9DBD1	Gene names	Polr3e, Sin
Domain Architecture
Description	DNA-directed RNA polymerases III 80 kDa polypeptide (EC 2.7.7.6) (RNA polymerase III subunit 5) (RPC5) (Sex-lethal interactor homolog).

WDR60_HUMAN
θ value	3.0926 (rank : 67)	NC score	0.019105 (rank : 98)
Query Neighborhood Hits	94	Target Neighborhood Hits	286	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WVS4, Q9NW58	Gene names	WDR60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

ATF6A_HUMAN
θ value	4.03905 (rank : 68)	NC score	0.032279 (rank : 78)
Query Neighborhood Hits	94	Target Neighborhood Hits	174	Shared Neighborhood Hits	10
SwissProt Accessions	P18850, O15139, Q5VW62, Q6IPB5, Q9UEC9	Gene names	ATF6
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 alpha (Activating transcription factor 6 alpha) (ATF6-alpha).

BHLH8_MOUSE
θ value	4.03905 (rank : 69)	NC score	0.055978 (rank : 62)
Query Neighborhood Hits	94	Target Neighborhood Hits	107	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QYC3, Q9QYE4	Gene names	Bhlhb8, Mist1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

BSN_MOUSE
θ value	4.03905 (rank : 70)	NC score	0.032975 (rank : 77)
Query Neighborhood Hits	94	Target Neighborhood Hits	2057	Shared Neighborhood Hits	30
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

FIGLA_HUMAN
θ value	4.03905 (rank : 71)	NC score	0.056040 (rank : 61)
Query Neighborhood Hits	94	Target Neighborhood Hits	108	Shared Neighborhood Hits	14
SwissProt Accessions	Q6QHK4	Gene names	FIGLA
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

IRX3_HUMAN
θ value	4.03905 (rank : 72)	NC score	0.009999 (rank : 106)
Query Neighborhood Hits	94	Target Neighborhood Hits	342	Shared Neighborhood Hits	3
SwissProt Accessions	P78415, Q7Z4A4, Q7Z4A5, Q8IVC6	Gene names	IRX3, IRXB1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1).

PTN12_MOUSE
θ value	4.03905 (rank : 73)	NC score	0.007460 (rank : 107)
Query Neighborhood Hits	94	Target Neighborhood Hits	123	Shared Neighborhood Hits	4
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

HES3_MOUSE
θ value	5.27518 (rank : 74)	NC score	0.055790 (rank : 63)
Query Neighborhood Hits	94	Target Neighborhood Hits	38	Shared Neighborhood Hits	12
SwissProt Accessions	Q61657, O09083, O09150	Gene names	Hes3, Hes-3
Domain Architecture
Description	Transcription factor HES-3 (Hairy and enhancer of split 3).

KCTD7_MOUSE
θ value	5.27518 (rank : 75)	NC score	0.017391 (rank : 100)
Query Neighborhood Hits	94	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BJK1, Q3USA6, Q8C0S7	Gene names	Kctd7
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD7.

MYH10_MOUSE
θ value	5.27518 (rank : 76)	NC score	0.017907 (rank : 99)
Query Neighborhood Hits	94	Target Neighborhood Hits	1612	Shared Neighborhood Hits	41
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

NDE1_HUMAN
θ value	5.27518 (rank : 77)	NC score	0.034724 (rank : 75)
Query Neighborhood Hits	94	Target Neighborhood Hits	823	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NXR1, Q49AQ2	Gene names	NDE1, NUDE
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE).

PCLO_HUMAN
θ value	5.27518 (rank : 78)	NC score	0.015382 (rank : 104)
Query Neighborhood Hits	94	Target Neighborhood Hits	2046	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

BHLH3_HUMAN
θ value	6.88961 (rank : 79)	NC score	0.156492 (rank : 34)
Query Neighborhood Hits	94	Target Neighborhood Hits	106	Shared Neighborhood Hits	36
SwissProt Accessions	Q9C0J9	Gene names	BHLHB3, DEC2, SHARP1
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (hDEC2) (Enhancer-of-split and hairy-related protein 1) (SHARP-1).

BSN_HUMAN
θ value	6.88961 (rank : 80)	NC score	0.036877 (rank : 71)
Query Neighborhood Hits	94	Target Neighborhood Hits	1537	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

HES2_MOUSE
θ value	6.88961 (rank : 81)	NC score	0.063377 (rank : 57)
Query Neighborhood Hits	94	Target Neighborhood Hits	36	Shared Neighborhood Hits	15
SwissProt Accessions	O54792	Gene names	Hes2
Domain Architecture
Description	Transcription factor HES-2 (Hairy and enhancer of split 2).

MYH9_HUMAN
θ value	6.88961 (rank : 82)	NC score	0.020361 (rank : 96)
Query Neighborhood Hits	94	Target Neighborhood Hits	1762	Shared Neighborhood Hits	48
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH9_MOUSE
θ value	6.88961 (rank : 83)	NC score	0.020045 (rank : 97)
Query Neighborhood Hits	94	Target Neighborhood Hits	1829	Shared Neighborhood Hits	45
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

NPHP1_HUMAN
θ value	6.88961 (rank : 84)	NC score	0.012021 (rank : 105)
Query Neighborhood Hits	94	Target Neighborhood Hits	288	Shared Neighborhood Hits	9
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

NUMA1_HUMAN
θ value	6.88961 (rank : 85)	NC score	0.027802 (rank : 85)
Query Neighborhood Hits	94	Target Neighborhood Hits	1523	Shared Neighborhood Hits	40
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

PEPL_HUMAN
θ value	6.88961 (rank : 86)	NC score	0.025219 (rank : 88)
Query Neighborhood Hits	94	Target Neighborhood Hits	1141	Shared Neighborhood Hits	36
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

RABE1_HUMAN
θ value	6.88961 (rank : 87)	NC score	0.029183 (rank : 83)
Query Neighborhood Hits	94	Target Neighborhood Hits	1104	Shared Neighborhood Hits	33
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

RABE1_MOUSE
θ value	6.88961 (rank : 88)	NC score	0.029186 (rank : 82)
Query Neighborhood Hits	94	Target Neighborhood Hits	1105	Shared Neighborhood Hits	35
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

ATF6B_HUMAN
θ value	8.99809 (rank : 89)	NC score	0.025147 (rank : 89)
Query Neighborhood Hits	94	Target Neighborhood Hits	122	Shared Neighborhood Hits	8
SwissProt Accessions	Q99941, Q13269, Q14343, Q14345, Q99635, Q99637, Q9H3V9, Q9H3W1, Q9NPL0	Gene names	CREBL1, G13
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp) (Protein G13).

BHLH3_MOUSE
θ value	8.99809 (rank : 90)	NC score	0.148468 (rank : 37)
Query Neighborhood Hits	94	Target Neighborhood Hits	70	Shared Neighborhood Hits	36
SwissProt Accessions	Q99PV5	Gene names	Bhlhb3, Dec2
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (mDEC2).

IF2M_MOUSE
θ value	8.99809 (rank : 91)	NC score	0.021374 (rank : 95)
Query Neighborhood Hits	94	Target Neighborhood Hits	183	Shared Neighborhood Hits	13
SwissProt Accessions	Q91YJ5	Gene names	Mtif2
Domain Architecture
Description	Translation initiation factor IF-2, mitochondrial precursor (IF-2Mt) (IF-2(Mt)).

LHX1_HUMAN
θ value	8.99809 (rank : 92)	NC score	0.000550 (rank : 110)
Query Neighborhood Hits	94	Target Neighborhood Hits	453	Shared Neighborhood Hits	2
SwissProt Accessions	P48742, Q3MIW0	Gene names	LHX1, LIM1
Domain Architecture
Description	LIM/homeobox protein Lhx1 (LIM homeobox protein 1) (Homeobox protein Lim-1).

MRE11_HUMAN
θ value	8.99809 (rank : 93)	NC score	0.015703 (rank : 103)
Query Neighborhood Hits	94	Target Neighborhood Hits	95	Shared Neighborhood Hits	10
SwissProt Accessions	P49959, O43475	Gene names	MRE11A, HNGS1, MRE11
Domain Architecture
Description	Double-strand break repair protein MRE11A (MRE11 homolog 1) (MRE11 meiotic recombination 11 homolog A).

PEPL_MOUSE
θ value	8.99809 (rank : 94)	NC score	0.024332 (rank : 90)
Query Neighborhood Hits	94	Target Neighborhood Hits	1105	Shared Neighborhood Hits	40
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

CLOCK_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.059750 (rank : 59)
Query Neighborhood Hits	94	Target Neighborhood Hits	127	Shared Neighborhood Hits	26
SwissProt Accessions	O15516, O14516, Q9UIT8	Gene names	CLOCK, KIAA0334
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (hCLOCK).

CLOCK_MOUSE
θ value	θ > 10 (rank : 96)	NC score	0.060036 (rank : 58)
Query Neighborhood Hits	94	Target Neighborhood Hits	148	Shared Neighborhood Hits	24
SwissProt Accessions	O08785	Gene names	Clock
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (mCLOCK).

HEY1_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.073348 (rank : 55)
Query Neighborhood Hits	94	Target Neighborhood Hits	82	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y5J3, Q5TZS3, Q9NYP4	Gene names	HEY1, CHF2, HESR1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).

HEY1_MOUSE
θ value	θ > 10 (rank : 98)	NC score	0.076790 (rank : 54)
Query Neighborhood Hits	94	Target Neighborhood Hits	69	Shared Neighborhood Hits	27
SwissProt Accessions	Q9WV93	Gene names	Hey1, Hesr1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).

HEY2_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.084757 (rank : 51)
Query Neighborhood Hits	94	Target Neighborhood Hits	77	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

HEY2_MOUSE
θ value	θ > 10 (rank : 100)	NC score	0.083646 (rank : 52)
Query Neighborhood Hits	94	Target Neighborhood Hits	80	Shared Neighborhood Hits	27
SwissProt Accessions	Q9QUS4, Q3TZ99, Q8CD44	Gene names	Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).

MAX_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.273519 (rank : 25)
Query Neighborhood Hits	94	Target Neighborhood Hits	125	Shared Neighborhood Hits	42
SwissProt Accessions	P61244, P25912, P52163	Gene names	MAX
Domain Architecture
Description	Protein max (Myc-associated factor X).

MAX_MOUSE
θ value	θ > 10 (rank : 102)	NC score	0.265659 (rank : 28)
Query Neighborhood Hits	94	Target Neighborhood Hits	139	Shared Neighborhood Hits	44
SwissProt Accessions	P28574	Gene names	Max, Myn
Domain Architecture
Description	Protein max (Myc-associated factor X) (Protein myn) (Myc-binding novel HLH/LZ protein).

MLX_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.083128 (rank : 53)
Query Neighborhood Hits	94	Target Neighborhood Hits	95	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MLX_MOUSE
θ value	θ > 10 (rank : 104)	NC score	0.089160 (rank : 50)
Query Neighborhood Hits	94	Target Neighborhood Hits	100	Shared Neighborhood Hits	30
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MYCB_MOUSE
θ value	θ > 10 (rank : 105)	NC score	0.131006 (rank : 44)
Query Neighborhood Hits	94	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q6P8Z1, Q9D6E3	Gene names	Mycb, Bmyc
Domain Architecture	No domain graphic available
Description	Protein B-Myc.

NPAS2_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.052697 (rank : 66)
Query Neighborhood Hits	94	Target Neighborhood Hits	150	Shared Neighborhood Hits	25
SwissProt Accessions	Q99743, Q99629	Gene names	NPAS2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2) (Member of PAS protein 4) (MOP4).

NPAS2_MOUSE
θ value	θ > 10 (rank : 107)	NC score	0.053426 (rank : 65)
Query Neighborhood Hits	94	Target Neighborhood Hits	132	Shared Neighborhood Hits	28
SwissProt Accessions	P97460	Gene names	Npas2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2).

SRBP1_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.160876 (rank : 33)
Query Neighborhood Hits	94	Target Neighborhood Hits	225	Shared Neighborhood Hits	39
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

TFAP4_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.093491 (rank : 49)
Query Neighborhood Hits	94	Target Neighborhood Hits	289	Shared Neighborhood Hits	33
SwissProt Accessions	Q01664, O60409	Gene names	TFAP4
Domain Architecture
Description	Transcription factor AP-4 (Activating enhancer-binding protein 4).

WBS14_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.059498 (rank : 60)
Query Neighborhood Hits	94	Target Neighborhood Hits	273	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

Hits sorted by NC score

MAD4_HUMAN
NC score	0.999962 (rank : 1)	θ value	3.66817e-102 (rank : 1)
Query Neighborhood Hits	94	Target Neighborhood Hits	94	Shared Neighborhood Hits	94
SwissProt Accessions	Q14582, Q5TZX4	Gene names	MXD4, MAD4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MAD4_MOUSE
NC score	0.974956 (rank : 2)	θ value	1.22395e-89 (rank : 2)
Query Neighborhood Hits	94	Target Neighborhood Hits	65	Shared Neighborhood Hits	54
SwissProt Accessions	Q60948	Gene names	Mxd4, Mad4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MXI1_HUMAN
NC score	0.924610 (rank : 3)	θ value	9.83387e-39 (rank : 4)
Query Neighborhood Hits	94	Target Neighborhood Hits	76	Shared Neighborhood Hits	39
SwissProt Accessions	P50539, Q15887	Gene names	MXI1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MXI1_MOUSE
NC score	0.920874 (rank : 4)	θ value	1.05066e-40 (rank : 3)
Query Neighborhood Hits	94	Target Neighborhood Hits	109	Shared Neighborhood Hits	45
SwissProt Accessions	P50540	Gene names	Mxi1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MAD1_MOUSE
NC score	0.907110 (rank : 5)	θ value	1.85459e-37 (rank : 6)
Query Neighborhood Hits	94	Target Neighborhood Hits	75	Shared Neighborhood Hits	40
SwissProt Accessions	P50538, Q60798, Q61825	Gene names	Mxd1, Mad, Mad1
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

MAD1_HUMAN
NC score	0.905169 (rank : 6)	θ value	6.37413e-38 (rank : 5)
Query Neighborhood Hits	94	Target Neighborhood Hits	68	Shared Neighborhood Hits	35
SwissProt Accessions	Q05195	Gene names	MXD1, MAD
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

MAD3_HUMAN
NC score	0.895203 (rank : 7)	θ value	5.06226e-27 (rank : 7)
Query Neighborhood Hits	94	Target Neighborhood Hits	92	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BW11, Q53HK1, Q7Z4Y0, Q8NDJ7, Q96ME3	Gene names	MXD3, MAD3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3) (Myx).

MAD3_MOUSE
NC score	0.889295 (rank : 8)	θ value	1.12775e-26 (rank : 8)
Query Neighborhood Hits	94	Target Neighborhood Hits	94	Shared Neighborhood Hits	36
SwissProt Accessions	Q80US8, Q60947	Gene names	Mxd3, Mad3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3).

MNT_MOUSE
NC score	0.442314 (rank : 9)	θ value	5.44631e-05 (rank : 9)
Query Neighborhood Hits	94	Target Neighborhood Hits	432	Shared Neighborhood Hits	44
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MNT_HUMAN
NC score	0.425144 (rank : 10)	θ value	0.000121331 (rank : 10)
Query Neighborhood Hits	94	Target Neighborhood Hits	496	Shared Neighborhood Hits	47
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MYC_MOUSE
NC score	0.359403 (rank : 11)	θ value	0.00035302 (rank : 12)
Query Neighborhood Hits	94	Target Neighborhood Hits	125	Shared Neighborhood Hits	35
SwissProt Accessions	P01108, P70247, Q3UM70, Q61422	Gene names	Myc
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

MYC_HUMAN
NC score	0.357277 (rank : 12)	θ value	0.000270298 (rank : 11)
Query Neighborhood Hits	94	Target Neighborhood Hits	146	Shared Neighborhood Hits	41
SwissProt Accessions	P01106, P01107, Q14026	Gene names	MYC
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

USF2_HUMAN
NC score	0.353202 (rank : 13)	θ value	0.00228821 (rank : 16)
Query Neighborhood Hits	94	Target Neighborhood Hits	155	Shared Neighborhood Hits	49
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

USF2_MOUSE
NC score	0.351793 (rank : 14)	θ value	0.00228821 (rank : 17)
Query Neighborhood Hits	94	Target Neighborhood Hits	173	Shared Neighborhood Hits	49
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

USF1_MOUSE
NC score	0.341337 (rank : 15)	θ value	0.00665767 (rank : 26)
Query Neighborhood Hits	94	Target Neighborhood Hits	71	Shared Neighborhood Hits	45
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF1_HUMAN
NC score	0.340362 (rank : 16)	θ value	0.00665767 (rank : 25)
Query Neighborhood Hits	94	Target Neighborhood Hits	70	Shared Neighborhood Hits	45
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

TFE3_HUMAN
NC score	0.312530 (rank : 17)	θ value	0.00035302 (rank : 13)
Query Neighborhood Hits	94	Target Neighborhood Hits	190	Shared Neighborhood Hits	50
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

MYCL2_HUMAN
NC score	0.308661 (rank : 18)	θ value	0.00509761 (rank : 20)
Query Neighborhood Hits	94	Target Neighborhood Hits	63	Shared Neighborhood Hits	26
SwissProt Accessions	P12525	Gene names	MYCL2
Domain Architecture
Description	L-myc-2 protein.

MITF_HUMAN
NC score	0.303060 (rank : 19)	θ value	0.00228821 (rank : 14)
Query Neighborhood Hits	94	Target Neighborhood Hits	113	Shared Neighborhood Hits	44
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MITF_MOUSE
NC score	0.294963 (rank : 20)	θ value	0.00298849 (rank : 18)
Query Neighborhood Hits	94	Target Neighborhood Hits	115	Shared Neighborhood Hits	45
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MYCL1_HUMAN
NC score	0.291756 (rank : 21)	θ value	0.0252991 (rank : 28)
Query Neighborhood Hits	94	Target Neighborhood Hits	146	Shared Neighborhood Hits	39
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYCN_MOUSE
NC score	0.290986 (rank : 22)	θ value	0.0113563 (rank : 27)
Query Neighborhood Hits	94	Target Neighborhood Hits	125	Shared Neighborhood Hits	38
SwissProt Accessions	P03966, Q61978	Gene names	Mycn, Nmyc, Nmyc1
Domain Architecture
Description	N-myc proto-oncogene protein.

MYCN_HUMAN
NC score	0.289872 (rank : 23)	θ value	0.00509761 (rank : 21)
Query Neighborhood Hits	94	Target Neighborhood Hits	127	Shared Neighborhood Hits	36
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.

MYCL1_MOUSE
NC score	0.287153 (rank : 24)	θ value	0.0563607 (rank : 32)
Query Neighborhood Hits	94	Target Neighborhood Hits	123	Shared Neighborhood Hits	39
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MAX_HUMAN
NC score	0.273519 (rank : 25)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	94	Target Neighborhood Hits	125	Shared Neighborhood Hits	42
SwissProt Accessions	P61244, P25912, P52163	Gene names	MAX
Domain Architecture
Description	Protein max (Myc-associated factor X).

TFEB_HUMAN
NC score	0.268062 (rank : 26)	θ value	0.00509761 (rank : 23)
Query Neighborhood Hits	94	Target Neighborhood Hits	111	Shared Neighborhood Hits	42
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

TFEB_MOUSE
NC score	0.267924 (rank : 27)	θ value	0.00390308 (rank : 19)
Query Neighborhood Hits	94	Target Neighborhood Hits	119	Shared Neighborhood Hits	41
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

MAX_MOUSE
NC score	0.265659 (rank : 28)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	94	Target Neighborhood Hits	139	Shared Neighborhood Hits	44
SwissProt Accessions	P28574	Gene names	Max, Myn
Domain Architecture
Description	Protein max (Myc-associated factor X) (Protein myn) (Myc-binding novel HLH/LZ protein).

MYCS_MOUSE
NC score	0.250475 (rank : 29)	θ value	0.125558 (rank : 33)
Query Neighborhood Hits	94	Target Neighborhood Hits	83	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z304	Gene names	Mycs
Domain Architecture
Description	Protein S-myc.

SRBP2_HUMAN
NC score	0.216620 (rank : 30)	θ value	0.00665767 (rank : 24)
Query Neighborhood Hits	94	Target Neighborhood Hits	133	Shared Neighborhood Hits	37
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

TCFL5_HUMAN
NC score	0.195729 (rank : 31)	θ value	2.36792 (rank : 61)
Query Neighborhood Hits	94	Target Neighborhood Hits	43	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UL49, O94771, Q9BYW0	Gene names	TCFL5, CHA, E2BP1
Domain Architecture	No domain graphic available
Description	Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).

SRBP1_MOUSE
NC score	0.185646 (rank : 32)	θ value	0.00509761 (rank : 22)
Query Neighborhood Hits	94	Target Neighborhood Hits	384	Shared Neighborhood Hits	42
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

SRBP1_HUMAN
NC score	0.160876 (rank : 33)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	94	Target Neighborhood Hits	225	Shared Neighborhood Hits	39
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

BHLH3_HUMAN
NC score	0.156492 (rank : 34)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	94	Target Neighborhood Hits	106	Shared Neighborhood Hits	36
SwissProt Accessions	Q9C0J9	Gene names	BHLHB3, DEC2, SHARP1
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (hDEC2) (Enhancer-of-split and hairy-related protein 1) (SHARP-1).

HES1_MOUSE
NC score	0.149368 (rank : 35)	θ value	0.365318 (rank : 41)
Query Neighborhood Hits	94	Target Neighborhood Hits	78	Shared Neighborhood Hits	29
SwissProt Accessions	P35428	Gene names	Hes1, Hes-1
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1).

HES1_HUMAN
NC score	0.148930 (rank : 36)	θ value	0.365318 (rank : 40)
Query Neighborhood Hits	94	Target Neighborhood Hits	76	Shared Neighborhood Hits	28
SwissProt Accessions	Q14469	Gene names	HES1, HL, HRY
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1) (Hairy- like) (HHL) (Hairy homolog).

BHLH3_MOUSE
NC score	0.148468 (rank : 37)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	94	Target Neighborhood Hits	70	Shared Neighborhood Hits	36
SwissProt Accessions	Q99PV5	Gene names	Bhlhb3, Dec2
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (mDEC2).

BHLH2_MOUSE
NC score	0.146579 (rank : 38)	θ value	0.813845 (rank : 48)
Query Neighborhood Hits	94	Target Neighborhood Hits	70	Shared Neighborhood Hits	35
SwissProt Accessions	O35185, P97289	Gene names	Bhlhb2, Clast5, Stra13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Stimulated with retinoic acid 13) (E47 interaction protein 1) (eipl).

ARNT_HUMAN
NC score	0.139403 (rank : 39)	θ value	0.163984 (rank : 34)
Query Neighborhood Hits	94	Target Neighborhood Hits	109	Shared Neighborhood Hits	38
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

BMAL1_HUMAN
NC score	0.137252 (rank : 40)	θ value	0.0431538 (rank : 30)
Query Neighborhood Hits	94	Target Neighborhood Hits	115	Shared Neighborhood Hits	37
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

BMAL1_MOUSE
NC score	0.136181 (rank : 41)	θ value	0.0563607 (rank : 31)
Query Neighborhood Hits	94	Target Neighborhood Hits	121	Shared Neighborhood Hits	37
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

BHLH2_HUMAN
NC score	0.134979 (rank : 42)	θ value	2.36792 (rank : 56)
Query Neighborhood Hits	94	Target Neighborhood Hits	80	Shared Neighborhood Hits	37
SwissProt Accessions	O14503, Q96TD3	Gene names	BHLHB2, DEC1, SHARP2, STRA13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Differentially expressed in chondrocytes protein 1) (DEC1) (Enhancer-of-split and hairy-related protein 2) (SHARP-2) (Stimulated with retinoic acid 13).

ARNT_MOUSE
NC score	0.131409 (rank : 43)	θ value	0.163984 (rank : 35)
Query Neighborhood Hits	94	Target Neighborhood Hits	213	Shared Neighborhood Hits	39
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

MYCB_MOUSE
NC score	0.131006 (rank : 44)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	94	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q6P8Z1, Q9D6E3	Gene names	Mycb, Bmyc
Domain Architecture	No domain graphic available
Description	Protein B-Myc.

RPC5_HUMAN
NC score	0.127382 (rank : 45)	θ value	0.00228821 (rank : 15)
Query Neighborhood Hits	94	Target Neighborhood Hits	36	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NVU0, Q9BWF7, Q9H8W8, Q9H907, Q9P276	Gene names	POLR3E, KIAA1452
Domain Architecture
Description	DNA-directed RNA polymerases III 80 kDa polypeptide (EC 2.7.7.6) (RNA polymerase III subunit 5) (RPC5).

ARNT2_MOUSE
NC score	0.123879 (rank : 46)	θ value	0.279714 (rank : 37)
Query Neighborhood Hits	94	Target Neighborhood Hits	115	Shared Neighborhood Hits	34
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT2_HUMAN
NC score	0.123502 (rank : 47)	θ value	0.279714 (rank : 36)
Query Neighborhood Hits	94	Target Neighborhood Hits	109	Shared Neighborhood Hits	34
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

HES4_HUMAN
NC score	0.117909 (rank : 48)	θ value	1.38821 (rank : 50)
Query Neighborhood Hits	94	Target Neighborhood Hits	58	Shared Neighborhood Hits	30
SwissProt Accessions	Q9HCC6	Gene names	HES4
Domain Architecture
Description	Transcription factor HES-4 (Hairy and enhancer of split 4) (bHLH factor Hes4).

TFAP4_HUMAN
NC score	0.093491 (rank : 49)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	94	Target Neighborhood Hits	289	Shared Neighborhood Hits	33
SwissProt Accessions	Q01664, O60409	Gene names	TFAP4
Domain Architecture
Description	Transcription factor AP-4 (Activating enhancer-binding protein 4).

MLX_MOUSE
NC score	0.089160 (rank : 50)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	94	Target Neighborhood Hits	100	Shared Neighborhood Hits	30
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

HEY2_HUMAN
NC score	0.084757 (rank : 51)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	94	Target Neighborhood Hits	77	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

HEY2_MOUSE
NC score	0.083646 (rank : 52)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	94	Target Neighborhood Hits	80	Shared Neighborhood Hits	27
SwissProt Accessions	Q9QUS4, Q3TZ99, Q8CD44	Gene names	Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).

MLX_HUMAN
NC score	0.083128 (rank : 53)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	94	Target Neighborhood Hits	95	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

HEY1_MOUSE
NC score	0.076790 (rank : 54)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	94	Target Neighborhood Hits	69	Shared Neighborhood Hits	27
SwissProt Accessions	Q9WV93	Gene names	Hey1, Hesr1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).

HEY1_HUMAN
NC score	0.073348 (rank : 55)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	94	Target Neighborhood Hits	82	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y5J3, Q5TZS3, Q9NYP4	Gene names	HEY1, CHF2, HESR1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).

RPC5_MOUSE
NC score	0.070138 (rank : 56)	θ value	3.0926 (rank : 66)
Query Neighborhood Hits	94	Target Neighborhood Hits	40	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CZT4, Q8CI35, Q9DBD1	Gene names	Polr3e, Sin
Domain Architecture
Description	DNA-directed RNA polymerases III 80 kDa polypeptide (EC 2.7.7.6) (RNA polymerase III subunit 5) (RPC5) (Sex-lethal interactor homolog).

HES2_MOUSE
NC score	0.063377 (rank : 57)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	94	Target Neighborhood Hits	36	Shared Neighborhood Hits	15
SwissProt Accessions	O54792	Gene names	Hes2
Domain Architecture
Description	Transcription factor HES-2 (Hairy and enhancer of split 2).

CLOCK_MOUSE
NC score	0.060036 (rank : 58)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	94	Target Neighborhood Hits	148	Shared Neighborhood Hits	24
SwissProt Accessions	O08785	Gene names	Clock
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (mCLOCK).

CLOCK_HUMAN
NC score	0.059750 (rank : 59)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	94	Target Neighborhood Hits	127	Shared Neighborhood Hits	26
SwissProt Accessions	O15516, O14516, Q9UIT8	Gene names	CLOCK, KIAA0334
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (hCLOCK).

WBS14_HUMAN
NC score	0.059498 (rank : 60)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	94	Target Neighborhood Hits	273	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

FIGLA_HUMAN
NC score	0.056040 (rank : 61)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	94	Target Neighborhood Hits	108	Shared Neighborhood Hits	14
SwissProt Accessions	Q6QHK4	Gene names	FIGLA
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

BHLH8_MOUSE
NC score	0.055978 (rank : 62)	θ value	4.03905 (rank : 69)
Query Neighborhood Hits	94	Target Neighborhood Hits	107	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QYC3, Q9QYE4	Gene names	Bhlhb8, Mist1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

HES3_MOUSE
NC score	0.055790 (rank : 63)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	94	Target Neighborhood Hits	38	Shared Neighborhood Hits	12
SwissProt Accessions	Q61657, O09083, O09150	Gene names	Hes3, Hes-3
Domain Architecture
Description	Transcription factor HES-3 (Hairy and enhancer of split 3).

CCDC6_HUMAN
NC score	0.054134 (rank : 64)	θ value	0.279714 (rank : 38)
Query Neighborhood Hits	94	Target Neighborhood Hits	723	Shared Neighborhood Hits	35
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

NPAS2_MOUSE
NC score	0.053426 (rank : 65)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	94	Target Neighborhood Hits	132	Shared Neighborhood Hits	28
SwissProt Accessions	P97460	Gene names	Npas2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2).

NPAS2_HUMAN
NC score	0.052697 (rank : 66)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	94	Target Neighborhood Hits	150	Shared Neighborhood Hits	25
SwissProt Accessions	Q99743, Q99629	Gene names	NPAS2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2) (Member of PAS protein 4) (MOP4).

HOOK1_HUMAN
NC score	0.045022 (rank : 67)	θ value	0.0330416 (rank : 29)
Query Neighborhood Hits	94	Target Neighborhood Hits	942	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

NONO_HUMAN
NC score	0.042893 (rank : 68)	θ value	0.47712 (rank : 43)
Query Neighborhood Hits	94	Target Neighborhood Hits	441	Shared Neighborhood Hits	17
SwissProt Accessions	Q15233, O00201, P30807, Q12786, Q9BQC5	Gene names	NONO, NRB54
Domain Architecture
Description	Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding p52/p100 complex, 52 kDa subunit).

NONO_MOUSE
NC score	0.042803 (rank : 69)	θ value	0.47712 (rank : 44)
Query Neighborhood Hits	94	Target Neighborhood Hits	444	Shared Neighborhood Hits	17
SwissProt Accessions	Q99K48, Q63887, Q9CYQ4, Q9DBP2	Gene names	Nono
Domain Architecture	No domain graphic available
Description	Non-POU domain-containing octamer-binding protein (NonO protein).

HOOK1_MOUSE
NC score	0.040977 (rank : 70)	θ value	0.365318 (rank : 42)
Query Neighborhood Hits	94	Target Neighborhood Hits	910	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

BSN_HUMAN
NC score	0.036877 (rank : 71)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	94	Target Neighborhood Hits	1537	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

XE7_HUMAN
NC score	0.036792 (rank : 72)	θ value	2.36792 (rank : 62)
Query Neighborhood Hits	94	Target Neighborhood Hits	738	Shared Neighborhood Hits	32
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

NDE1_MOUSE
NC score	0.036132 (rank : 73)	θ value	1.81305 (rank : 54)
Query Neighborhood Hits	94	Target Neighborhood Hits	602	Shared Neighborhood Hits	28
SwissProt Accessions	Q9CZA6, Q3UBS6, Q3UIC1, Q9ERR0	Gene names	Nde1, Nude
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE) (mNudE).

CING_MOUSE
NC score	0.035403 (rank : 74)	θ value	3.0926 (rank : 64)
Query Neighborhood Hits	94	Target Neighborhood Hits	1432	Shared Neighborhood Hits	42
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

NDE1_HUMAN
NC score	0.034724 (rank : 75)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	94	Target Neighborhood Hits	823	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NXR1, Q49AQ2	Gene names	NDE1, NUDE
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE).

TRIPB_HUMAN
NC score	0.034343 (rank : 76)	θ value	1.38821 (rank : 51)
Query Neighborhood Hits	94	Target Neighborhood Hits	1587	Shared Neighborhood Hits	44
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

BSN_MOUSE
NC score	0.032975 (rank : 77)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	94	Target Neighborhood Hits	2057	Shared Neighborhood Hits	30
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

ATF6A_HUMAN
NC score	0.032279 (rank : 78)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	94	Target Neighborhood Hits	174	Shared Neighborhood Hits	10
SwissProt Accessions	P18850, O15139, Q5VW62, Q6IPB5, Q9UEC9	Gene names	ATF6
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 alpha (Activating transcription factor 6 alpha) (ATF6-alpha).

KTN1_HUMAN
NC score	0.031711 (rank : 79)	θ value	0.62314 (rank : 46)
Query Neighborhood Hits	94	Target Neighborhood Hits	1197	Shared Neighborhood Hits	35
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

TRHY_HUMAN
NC score	0.030975 (rank : 80)	θ value	0.62314 (rank : 47)
Query Neighborhood Hits	94	Target Neighborhood Hits	1385	Shared Neighborhood Hits	36
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

GBP1_HUMAN
NC score	0.029973 (rank : 81)	θ value	0.62314 (rank : 45)
Query Neighborhood Hits	94	Target Neighborhood Hits	339	Shared Neighborhood Hits	21
SwissProt Accessions	P32455	Gene names	GBP1
Domain Architecture
Description	Interferon-induced guanylate-binding protein 1 (GTP-binding protein 1) (Guanine nucleotide-binding protein 1) (GBP-1) (HuGBP-1).

RABE1_MOUSE
NC score	0.029186 (rank : 82)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	94	Target Neighborhood Hits	1105	Shared Neighborhood Hits	35
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

RABE1_HUMAN
NC score	0.029183 (rank : 83)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	94	Target Neighborhood Hits	1104	Shared Neighborhood Hits	33
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

EEA1_MOUSE
NC score	0.028060 (rank : 84)	θ value	2.36792 (rank : 58)
Query Neighborhood Hits	94	Target Neighborhood Hits	1637	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

NUMA1_HUMAN
NC score	0.027802 (rank : 85)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	94	Target Neighborhood Hits	1523	Shared Neighborhood Hits	40
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

ENAH_MOUSE
NC score	0.027266 (rank : 86)	θ value	0.279714 (rank : 39)
Query Neighborhood Hits	94	Target Neighborhood Hits	919	Shared Neighborhood Hits	26
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

EEA1_HUMAN
NC score	0.026227 (rank : 87)	θ value	2.36792 (rank : 57)
Query Neighborhood Hits	94	Target Neighborhood Hits	1796	Shared Neighborhood Hits	40
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

PEPL_HUMAN
NC score	0.025219 (rank : 88)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	94	Target Neighborhood Hits	1141	Shared Neighborhood Hits	36
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

ATF6B_HUMAN
NC score	0.025147 (rank : 89)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	94	Target Neighborhood Hits	122	Shared Neighborhood Hits	8
SwissProt Accessions	Q99941, Q13269, Q14343, Q14345, Q99635, Q99637, Q9H3V9, Q9H3W1, Q9NPL0	Gene names	CREBL1, G13
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp) (Protein G13).

PEPL_MOUSE
NC score	0.024332 (rank : 90)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	94	Target Neighborhood Hits	1105	Shared Neighborhood Hits	40
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

MOES_HUMAN
NC score	0.023663 (rank : 91)	θ value	1.81305 (rank : 53)
Query Neighborhood Hits	94	Target Neighborhood Hits	892	Shared Neighborhood Hits	30
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

INCE_MOUSE
NC score	0.023447 (rank : 92)	θ value	3.0926 (rank : 65)
Query Neighborhood Hits	94	Target Neighborhood Hits	903	Shared Neighborhood Hits	30
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

AN30A_HUMAN
NC score	0.023226 (rank : 93)	θ value	2.36792 (rank : 55)
Query Neighborhood Hits	94	Target Neighborhood Hits	1119	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

MOES_MOUSE
NC score	0.021763 (rank : 94)	θ value	1.06291 (rank : 49)
Query Neighborhood Hits	94	Target Neighborhood Hits	923	Shared Neighborhood Hits	27
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

IF2M_MOUSE
NC score	0.021374 (rank : 95)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	94	Target Neighborhood Hits	183	Shared Neighborhood Hits	13
SwissProt Accessions	Q91YJ5	Gene names	Mtif2
Domain Architecture
Description	Translation initiation factor IF-2, mitochondrial precursor (IF-2Mt) (IF-2(Mt)).

MYH9_HUMAN
NC score	0.020361 (rank : 96)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	94	Target Neighborhood Hits	1762	Shared Neighborhood Hits	48
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH9_MOUSE
NC score	0.020045 (rank : 97)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	94	Target Neighborhood Hits	1829	Shared Neighborhood Hits	45
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

WDR60_HUMAN
NC score	0.019105 (rank : 98)	θ value	3.0926 (rank : 67)
Query Neighborhood Hits	94	Target Neighborhood Hits	286	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WVS4, Q9NW58	Gene names	WDR60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

MYH10_MOUSE
NC score	0.017907 (rank : 99)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	94	Target Neighborhood Hits	1612	Shared Neighborhood Hits	41
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

KCTD7_MOUSE
NC score	0.017391 (rank : 100)	θ value	5.27518 (rank : 75)
Query Neighborhood Hits	94	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BJK1, Q3USA6, Q8C0S7	Gene names	Kctd7
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD7.

ARI1_MOUSE
NC score	0.016628 (rank : 101)	θ value	1.81305 (rank : 52)
Query Neighborhood Hits	94	Target Neighborhood Hits	71	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z1K5, Q6PF92	Gene names	Arih1, Ari, Ubch7bp, Uip77
Domain Architecture	No domain graphic available
Description	Protein ariadne-1 homolog (ARI-1) (Ubiquitin-conjugating enzyme E2- binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein 77).

BAZ1A_HUMAN
NC score	0.016070 (rank : 102)	θ value	3.0926 (rank : 63)
Query Neighborhood Hits	94	Target Neighborhood Hits	693	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

MRE11_HUMAN
NC score	0.015703 (rank : 103)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	94	Target Neighborhood Hits	95	Shared Neighborhood Hits	10
SwissProt Accessions	P49959, O43475	Gene names	MRE11A, HNGS1, MRE11
Domain Architecture
Description	Double-strand break repair protein MRE11A (MRE11 homolog 1) (MRE11 meiotic recombination 11 homolog A).

PCLO_HUMAN
NC score	0.015382 (rank : 104)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	94	Target Neighborhood Hits	2046	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

NPHP1_HUMAN
NC score	0.012021 (rank : 105)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	94	Target Neighborhood Hits	288	Shared Neighborhood Hits	9
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

IRX3_HUMAN
NC score	0.009999 (rank : 106)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	94	Target Neighborhood Hits	342	Shared Neighborhood Hits	3
SwissProt Accessions	P78415, Q7Z4A4, Q7Z4A5, Q8IVC6	Gene names	IRX3, IRXB1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1).

PTN12_MOUSE
NC score	0.007460 (rank : 107)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	94	Target Neighborhood Hits	123	Shared Neighborhood Hits	4
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

MINK1_MOUSE
NC score	0.005210 (rank : 108)	θ value	2.36792 (rank : 60)
Query Neighborhood Hits	94	Target Neighborhood Hits	1451	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MINK1_HUMAN
NC score	0.005195 (rank : 109)	θ value	2.36792 (rank : 59)
Query Neighborhood Hits	94	Target Neighborhood Hits	1477	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

LHX1_HUMAN
NC score	0.000550 (rank : 110)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	94	Target Neighborhood Hits	453	Shared Neighborhood Hits	2
SwissProt Accessions	P48742, Q3MIW0	Gene names	LHX1, LIM1
Domain Architecture
Description	LIM/homeobox protein Lhx1 (LIM homeobox protein 1) (Homeobox protein Lim-1).