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Network neighborhood for query Sequence : METL2_HUMAN

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METL2_HUMAN
SwissProt Accessions	Q96IZ6, Q9H9G9, Q9NUI8, Q9P0B5	Gene names	METTL2
Domain Architecture
Description	Methyltransferase-like protein 2 (EC 2.1.1.-).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

METL2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	Q96IZ6, Q9H9G9, Q9NUI8, Q9P0B5	Gene names	METTL2
Domain Architecture
Description	Methyltransferase-like protein 2 (EC 2.1.1.-).

METL2_MOUSE
θ value	5.18743e-173 (rank : 2)	NC score	0.994350 (rank : 2)
Query Neighborhood Hits	18	Target Neighborhood Hits	17	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BMK1, Q8BXC2	Gene names	Mettl2, D11Ertd768e
Domain Architecture
Description	Methyltransferase-like protein 2 (EC 2.1.1.-).

METL6_HUMAN
θ value	1.01529e-43 (rank : 3)	NC score	0.873795 (rank : 3)
Query Neighborhood Hits	18	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TCB7, Q96LU4	Gene names	METTL6
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 6 (EC 2.1.1.-).

METL6_MOUSE
θ value	2.11701e-41 (rank : 4)	NC score	0.864726 (rank : 4)
Query Neighborhood Hits	18	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BVH9, Q9D9M6, Q9DAX6	Gene names	Mettl6
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 6 (EC 2.1.1.-).

MET7A_HUMAN
θ value	5.44631e-05 (rank : 5)	NC score	0.271238 (rank : 5)
Query Neighborhood Hits	18	Target Neighborhood Hits	13	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H8H3, Q9H7R3, Q9UHZ7, Q9Y422	Gene names	METTL7A
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 7A precursor (EC 2.1.1.-) (Protein AAM- B).

COQ3_MOUSE
θ value	0.0252991 (rank : 6)	NC score	0.148907 (rank : 8)
Query Neighborhood Hits	18	Target Neighborhood Hits	15	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BMS4, Q3TCX5, Q6P918, Q8BM28	Gene names	Coq3
Domain Architecture	No domain graphic available
Description	Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial precursor (EC 2.1.1.114) (Dihydroxyhexaprenylbenzoate methyltransferase) (3,4- dihydroxy-5-hexaprenylbenzoate methyltransferase) (DHHB methyltransferase) (DHHB-MT) (DHHB-MTase).

MET7B_HUMAN
θ value	0.0330416 (rank : 7)	NC score	0.191236 (rank : 6)
Query Neighborhood Hits	18	Target Neighborhood Hits	17	Shared Neighborhood Hits	6
SwissProt Accessions	Q6UX53, Q8WUI1	Gene names	METTL7B
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 7B precursor (EC 2.1.1.-).

COQ3_HUMAN
θ value	0.0961366 (rank : 8)	NC score	0.126573 (rank : 9)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZJ6, Q6P4F0, Q8IXG6, Q96BG1, Q9H0N1	Gene names	COQ3
Domain Architecture
Description	Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial precursor (EC 2.1.1.114) (Dihydroxyhexaprenylbenzoate methyltransferase) (3,4- dihydroxy-5-hexaprenylbenzoate methyltransferase) (DHHB methyltransferase) (DHHB-MT) (DHHB-MTase).

MYC_HUMAN
θ value	0.365318 (rank : 9)	NC score	0.046009 (rank : 14)
Query Neighborhood Hits	18	Target Neighborhood Hits	146	Shared Neighborhood Hits	3
SwissProt Accessions	P01106, P01107, Q14026	Gene names	MYC
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

PNMT_MOUSE
θ value	0.47712 (rank : 10)	NC score	0.097528 (rank : 12)
Query Neighborhood Hits	18	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	P40935	Gene names	Pnmt
Domain Architecture
Description	Phenylethanolamine N-methyltransferase (EC 2.1.1.28) (PNMTase) (Noradrenaline N-methyltransferase).

MET7B_MOUSE
θ value	0.62314 (rank : 11)	NC score	0.167441 (rank : 7)
Query Neighborhood Hits	18	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DD20, Q78ID2	Gene names	Mettl7b
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 7B precursor (EC 2.1.1.-).

PNMT_HUMAN
θ value	0.62314 (rank : 12)	NC score	0.097577 (rank : 11)
Query Neighborhood Hits	18	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	P11086	Gene names	PNMT, PENT
Domain Architecture
Description	Phenylethanolamine N-methyltransferase (EC 2.1.1.28) (PNMTase) (Noradrenaline N-methyltransferase).

NNMT_HUMAN
θ value	0.813845 (rank : 13)	NC score	0.104648 (rank : 10)
Query Neighborhood Hits	18	Target Neighborhood Hits	11	Shared Neighborhood Hits	7
SwissProt Accessions	P40261	Gene names	NNMT
Domain Architecture
Description	Nicotinamide N-methyltransferase (EC 2.1.1.1).

NNMT_MOUSE
θ value	1.06291 (rank : 14)	NC score	0.088918 (rank : 13)
Query Neighborhood Hits	18	Target Neighborhood Hits	11	Shared Neighborhood Hits	7
SwissProt Accessions	O55239	Gene names	Nnmt
Domain Architecture
Description	Nicotinamide N-methyltransferase (EC 2.1.1.1).

MYC_MOUSE
θ value	3.0926 (rank : 15)	NC score	0.036458 (rank : 15)
Query Neighborhood Hits	18	Target Neighborhood Hits	125	Shared Neighborhood Hits	3
SwissProt Accessions	P01108, P70247, Q3UM70, Q61422	Gene names	Myc
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

ANR15_HUMAN
θ value	5.27518 (rank : 16)	NC score	0.008395 (rank : 18)
Query Neighborhood Hits	18	Target Neighborhood Hits	478	Shared Neighborhood Hits	2
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

RASF8_HUMAN
θ value	6.88961 (rank : 17)	NC score	0.009047 (rank : 17)
Query Neighborhood Hits	18	Target Neighborhood Hits	469	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NHQ8, O95647, Q5SCI2, Q76KB6	Gene names	RASSF8, C12orf2
Domain Architecture
Description	Ras association domain-containing protein 8 (Carcinoma-associated protein HOJ-1).

HEMK1_HUMAN
θ value	8.99809 (rank : 18)	NC score	0.025714 (rank : 16)
Query Neighborhood Hits	18	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5R4	Gene names	HEMK1, HEMK
Domain Architecture
Description	HemK methyltransferase family member 1 (EC 2.1.1.-) (M.HsaHemKP).

Hits sorted by NC score

METL2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	Q96IZ6, Q9H9G9, Q9NUI8, Q9P0B5	Gene names	METTL2
Domain Architecture
Description	Methyltransferase-like protein 2 (EC 2.1.1.-).

METL2_MOUSE
NC score	0.994350 (rank : 2)	θ value	5.18743e-173 (rank : 2)
Query Neighborhood Hits	18	Target Neighborhood Hits	17	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BMK1, Q8BXC2	Gene names	Mettl2, D11Ertd768e
Domain Architecture
Description	Methyltransferase-like protein 2 (EC 2.1.1.-).

METL6_HUMAN
NC score	0.873795 (rank : 3)	θ value	1.01529e-43 (rank : 3)
Query Neighborhood Hits	18	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TCB7, Q96LU4	Gene names	METTL6
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 6 (EC 2.1.1.-).

METL6_MOUSE
NC score	0.864726 (rank : 4)	θ value	2.11701e-41 (rank : 4)
Query Neighborhood Hits	18	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BVH9, Q9D9M6, Q9DAX6	Gene names	Mettl6
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 6 (EC 2.1.1.-).

MET7A_HUMAN
NC score	0.271238 (rank : 5)	θ value	5.44631e-05 (rank : 5)
Query Neighborhood Hits	18	Target Neighborhood Hits	13	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H8H3, Q9H7R3, Q9UHZ7, Q9Y422	Gene names	METTL7A
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 7A precursor (EC 2.1.1.-) (Protein AAM- B).

MET7B_HUMAN
NC score	0.191236 (rank : 6)	θ value	0.0330416 (rank : 7)
Query Neighborhood Hits	18	Target Neighborhood Hits	17	Shared Neighborhood Hits	6
SwissProt Accessions	Q6UX53, Q8WUI1	Gene names	METTL7B
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 7B precursor (EC 2.1.1.-).

MET7B_MOUSE
NC score	0.167441 (rank : 7)	θ value	0.62314 (rank : 11)
Query Neighborhood Hits	18	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DD20, Q78ID2	Gene names	Mettl7b
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 7B precursor (EC 2.1.1.-).

COQ3_MOUSE
NC score	0.148907 (rank : 8)	θ value	0.0252991 (rank : 6)
Query Neighborhood Hits	18	Target Neighborhood Hits	15	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BMS4, Q3TCX5, Q6P918, Q8BM28	Gene names	Coq3
Domain Architecture	No domain graphic available
Description	Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial precursor (EC 2.1.1.114) (Dihydroxyhexaprenylbenzoate methyltransferase) (3,4- dihydroxy-5-hexaprenylbenzoate methyltransferase) (DHHB methyltransferase) (DHHB-MT) (DHHB-MTase).

COQ3_HUMAN
NC score	0.126573 (rank : 9)	θ value	0.0961366 (rank : 8)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZJ6, Q6P4F0, Q8IXG6, Q96BG1, Q9H0N1	Gene names	COQ3
Domain Architecture
Description	Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial precursor (EC 2.1.1.114) (Dihydroxyhexaprenylbenzoate methyltransferase) (3,4- dihydroxy-5-hexaprenylbenzoate methyltransferase) (DHHB methyltransferase) (DHHB-MT) (DHHB-MTase).

NNMT_HUMAN
NC score	0.104648 (rank : 10)	θ value	0.813845 (rank : 13)
Query Neighborhood Hits	18	Target Neighborhood Hits	11	Shared Neighborhood Hits	7
SwissProt Accessions	P40261	Gene names	NNMT
Domain Architecture
Description	Nicotinamide N-methyltransferase (EC 2.1.1.1).

PNMT_HUMAN
NC score	0.097577 (rank : 11)	θ value	0.62314 (rank : 12)
Query Neighborhood Hits	18	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	P11086	Gene names	PNMT, PENT
Domain Architecture
Description	Phenylethanolamine N-methyltransferase (EC 2.1.1.28) (PNMTase) (Noradrenaline N-methyltransferase).

PNMT_MOUSE
NC score	0.097528 (rank : 12)	θ value	0.47712 (rank : 10)
Query Neighborhood Hits	18	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	P40935	Gene names	Pnmt
Domain Architecture
Description	Phenylethanolamine N-methyltransferase (EC 2.1.1.28) (PNMTase) (Noradrenaline N-methyltransferase).

NNMT_MOUSE
NC score	0.088918 (rank : 13)	θ value	1.06291 (rank : 14)
Query Neighborhood Hits	18	Target Neighborhood Hits	11	Shared Neighborhood Hits	7
SwissProt Accessions	O55239	Gene names	Nnmt
Domain Architecture
Description	Nicotinamide N-methyltransferase (EC 2.1.1.1).

MYC_HUMAN
NC score	0.046009 (rank : 14)	θ value	0.365318 (rank : 9)
Query Neighborhood Hits	18	Target Neighborhood Hits	146	Shared Neighborhood Hits	3
SwissProt Accessions	P01106, P01107, Q14026	Gene names	MYC
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

MYC_MOUSE
NC score	0.036458 (rank : 15)	θ value	3.0926 (rank : 15)
Query Neighborhood Hits	18	Target Neighborhood Hits	125	Shared Neighborhood Hits	3
SwissProt Accessions	P01108, P70247, Q3UM70, Q61422	Gene names	Myc
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

HEMK1_HUMAN
NC score	0.025714 (rank : 16)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	18	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5R4	Gene names	HEMK1, HEMK
Domain Architecture
Description	HemK methyltransferase family member 1 (EC 2.1.1.-) (M.HsaHemKP).

RASF8_HUMAN
NC score	0.009047 (rank : 17)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	18	Target Neighborhood Hits	469	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NHQ8, O95647, Q5SCI2, Q76KB6	Gene names	RASSF8, C12orf2
Domain Architecture
Description	Ras association domain-containing protein 8 (Carcinoma-associated protein HOJ-1).

ANR15_HUMAN
NC score	0.008395 (rank : 18)	θ value	5.27518 (rank : 16)
Query Neighborhood Hits	18	Target Neighborhood Hits	478	Shared Neighborhood Hits	2
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).