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Network neighborhood for query Sequence : METL6_HUMAN

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METL6_HUMAN
SwissProt Accessions	Q8TCB7, Q96LU4	Gene names	METTL6
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 6 (EC 2.1.1.-).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

METL6_HUMAN
θ value	1.51984e-148 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TCB7, Q96LU4	Gene names	METTL6
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 6 (EC 2.1.1.-).

METL6_MOUSE
θ value	5.24793e-133 (rank : 2)	NC score	0.993950 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BVH9, Q9D9M6, Q9DAX6	Gene names	Mettl6
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 6 (EC 2.1.1.-).

METL2_HUMAN
θ value	1.01529e-43 (rank : 3)	NC score	0.873795 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q96IZ6, Q9H9G9, Q9NUI8, Q9P0B5	Gene names	METTL2
Domain Architecture
Description	Methyltransferase-like protein 2 (EC 2.1.1.-).

METL2_MOUSE
θ value	3.61106e-41 (rank : 4)	NC score	0.873158 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	17	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BMK1, Q8BXC2	Gene names	Mettl2, D11Ertd768e
Domain Architecture
Description	Methyltransferase-like protein 2 (EC 2.1.1.-).

MET7A_HUMAN
θ value	0.0148317 (rank : 5)	NC score	0.205172 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H8H3, Q9H7R3, Q9UHZ7, Q9Y422	Gene names	METTL7A
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 7A precursor (EC 2.1.1.-) (Protein AAM- B).

NNMT_HUMAN
θ value	0.0563607 (rank : 6)	NC score	0.093114 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	11	Shared Neighborhood Hits	5
SwissProt Accessions	P40261	Gene names	NNMT
Domain Architecture
Description	Nicotinamide N-methyltransferase (EC 2.1.1.1).

PON3_MOUSE
θ value	0.365318 (rank : 7)	NC score	0.057517 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q62087, Q8C2I7	Gene names	Pon3
Domain Architecture
Description	Serum paraoxonase/lactonase 3 (EC 3.1.1.-).

AS3MT_MOUSE
θ value	1.81305 (rank : 8)	NC score	0.042797 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q91WU5, Q9QZT1	Gene names	As3mt, Cyt19
Domain Architecture	No domain graphic available
Description	Arsenite methyltransferase (EC 2.1.1.137) (S-adenosyl-L- methionine:arsenic(III) methyltransferase) (Methylarsonite methyltransferase).

HEMK1_MOUSE
θ value	1.81305 (rank : 9)	NC score	0.054425 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q921L7	Gene names	Hemk1
Domain Architecture	No domain graphic available
Description	HemK methyltransferase family member 1 (EC 2.1.1.-).

NNMT_MOUSE
θ value	1.81305 (rank : 10)	NC score	0.072421 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	11	Shared Neighborhood Hits	5
SwissProt Accessions	O55239	Gene names	Nnmt
Domain Architecture
Description	Nicotinamide N-methyltransferase (EC 2.1.1.1).

HEMK1_HUMAN
θ value	2.36792 (rank : 11)	NC score	0.057868 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y5R4	Gene names	HEMK1, HEMK
Domain Architecture
Description	HemK methyltransferase family member 1 (EC 2.1.1.-) (M.HsaHemKP).

MET7B_HUMAN
θ value	3.0926 (rank : 12)	NC score	0.125052 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	17	Shared Neighborhood Hits	7
SwissProt Accessions	Q6UX53, Q8WUI1	Gene names	METTL7B
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 7B precursor (EC 2.1.1.-).

MET7B_MOUSE
θ value	3.0926 (rank : 13)	NC score	0.111380 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	Q9DD20, Q78ID2	Gene names	Mettl7b
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 7B precursor (EC 2.1.1.-).

ANR11_HUMAN
θ value	5.27518 (rank : 14)	NC score	0.006778 (rank : 17)
Query Neighborhood Hits	15	Target Neighborhood Hits	1289	Shared Neighborhood Hits	2
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

U2AFL_HUMAN
θ value	5.27518 (rank : 15)	NC score	0.011919 (rank : 16)
Query Neighborhood Hits	15	Target Neighborhood Hits	503	Shared Neighborhood Hits	2
SwissProt Accessions	Q15695, Q13570	Gene names	ZRSR1, U2AF1-RS1, U2AF1L1, U2AF1RS1, U2AFBPL
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 1 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1).

PNMT_HUMAN
θ value	θ > 10 (rank : 16)	NC score	0.053052 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	P11086	Gene names	PNMT, PENT
Domain Architecture
Description	Phenylethanolamine N-methyltransferase (EC 2.1.1.28) (PNMTase) (Noradrenaline N-methyltransferase).

PNMT_MOUSE
θ value	θ > 10 (rank : 17)	NC score	0.052771 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	P40935	Gene names	Pnmt
Domain Architecture
Description	Phenylethanolamine N-methyltransferase (EC 2.1.1.28) (PNMTase) (Noradrenaline N-methyltransferase).

Hits sorted by NC score

METL6_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.51984e-148 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TCB7, Q96LU4	Gene names	METTL6
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 6 (EC 2.1.1.-).

METL6_MOUSE
NC score	0.993950 (rank : 2)	θ value	5.24793e-133 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BVH9, Q9D9M6, Q9DAX6	Gene names	Mettl6
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 6 (EC 2.1.1.-).

METL2_HUMAN
NC score	0.873795 (rank : 3)	θ value	1.01529e-43 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q96IZ6, Q9H9G9, Q9NUI8, Q9P0B5	Gene names	METTL2
Domain Architecture
Description	Methyltransferase-like protein 2 (EC 2.1.1.-).

METL2_MOUSE
NC score	0.873158 (rank : 4)	θ value	3.61106e-41 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	17	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BMK1, Q8BXC2	Gene names	Mettl2, D11Ertd768e
Domain Architecture
Description	Methyltransferase-like protein 2 (EC 2.1.1.-).

MET7A_HUMAN
NC score	0.205172 (rank : 5)	θ value	0.0148317 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H8H3, Q9H7R3, Q9UHZ7, Q9Y422	Gene names	METTL7A
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 7A precursor (EC 2.1.1.-) (Protein AAM- B).

MET7B_HUMAN
NC score	0.125052 (rank : 6)	θ value	3.0926 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	17	Shared Neighborhood Hits	7
SwissProt Accessions	Q6UX53, Q8WUI1	Gene names	METTL7B
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 7B precursor (EC 2.1.1.-).

MET7B_MOUSE
NC score	0.111380 (rank : 7)	θ value	3.0926 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	Q9DD20, Q78ID2	Gene names	Mettl7b
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 7B precursor (EC 2.1.1.-).

NNMT_HUMAN
NC score	0.093114 (rank : 8)	θ value	0.0563607 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	11	Shared Neighborhood Hits	5
SwissProt Accessions	P40261	Gene names	NNMT
Domain Architecture
Description	Nicotinamide N-methyltransferase (EC 2.1.1.1).

NNMT_MOUSE
NC score	0.072421 (rank : 9)	θ value	1.81305 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	11	Shared Neighborhood Hits	5
SwissProt Accessions	O55239	Gene names	Nnmt
Domain Architecture
Description	Nicotinamide N-methyltransferase (EC 2.1.1.1).

HEMK1_HUMAN
NC score	0.057868 (rank : 10)	θ value	2.36792 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y5R4	Gene names	HEMK1, HEMK
Domain Architecture
Description	HemK methyltransferase family member 1 (EC 2.1.1.-) (M.HsaHemKP).

PON3_MOUSE
NC score	0.057517 (rank : 11)	θ value	0.365318 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q62087, Q8C2I7	Gene names	Pon3
Domain Architecture
Description	Serum paraoxonase/lactonase 3 (EC 3.1.1.-).

HEMK1_MOUSE
NC score	0.054425 (rank : 12)	θ value	1.81305 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q921L7	Gene names	Hemk1
Domain Architecture	No domain graphic available
Description	HemK methyltransferase family member 1 (EC 2.1.1.-).

PNMT_HUMAN
NC score	0.053052 (rank : 13)	θ value	θ > 10 (rank : 16)
Query Neighborhood Hits	15	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	P11086	Gene names	PNMT, PENT
Domain Architecture
Description	Phenylethanolamine N-methyltransferase (EC 2.1.1.28) (PNMTase) (Noradrenaline N-methyltransferase).

PNMT_MOUSE
NC score	0.052771 (rank : 14)	θ value	θ > 10 (rank : 17)
Query Neighborhood Hits	15	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	P40935	Gene names	Pnmt
Domain Architecture
Description	Phenylethanolamine N-methyltransferase (EC 2.1.1.28) (PNMTase) (Noradrenaline N-methyltransferase).

AS3MT_MOUSE
NC score	0.042797 (rank : 15)	θ value	1.81305 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q91WU5, Q9QZT1	Gene names	As3mt, Cyt19
Domain Architecture	No domain graphic available
Description	Arsenite methyltransferase (EC 2.1.1.137) (S-adenosyl-L- methionine:arsenic(III) methyltransferase) (Methylarsonite methyltransferase).

U2AFL_HUMAN
NC score	0.011919 (rank : 16)	θ value	5.27518 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	503	Shared Neighborhood Hits	2
SwissProt Accessions	Q15695, Q13570	Gene names	ZRSR1, U2AF1-RS1, U2AF1L1, U2AF1RS1, U2AFBPL
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 1 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1).

ANR11_HUMAN
NC score	0.006778 (rank : 17)	θ value	5.27518 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	1289	Shared Neighborhood Hits	2
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).