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Network neighborhood for query Sequence : COQ3_HUMAN

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COQ3_HUMAN
SwissProt Accessions	Q9NZJ6, Q6P4F0, Q8IXG6, Q96BG1, Q9H0N1	Gene names	COQ3
Domain Architecture
Description	Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial precursor (EC 2.1.1.114) (Dihydroxyhexaprenylbenzoate methyltransferase) (3,4- dihydroxy-5-hexaprenylbenzoate methyltransferase) (DHHB methyltransferase) (DHHB-MT) (DHHB-MTase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

COQ3_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NZJ6, Q6P4F0, Q8IXG6, Q96BG1, Q9H0N1	Gene names	COQ3
Domain Architecture
Description	Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial precursor (EC 2.1.1.114) (Dihydroxyhexaprenylbenzoate methyltransferase) (3,4- dihydroxy-5-hexaprenylbenzoate methyltransferase) (DHHB methyltransferase) (DHHB-MT) (DHHB-MTase).

COQ3_MOUSE
θ value	5.96274e-153 (rank : 2)	NC score	0.987828 (rank : 2)
Query Neighborhood Hits	18	Target Neighborhood Hits	15	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BMS4, Q3TCX5, Q6P918, Q8BM28	Gene names	Coq3
Domain Architecture	No domain graphic available
Description	Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial precursor (EC 2.1.1.114) (Dihydroxyhexaprenylbenzoate methyltransferase) (3,4- dihydroxy-5-hexaprenylbenzoate methyltransferase) (DHHB methyltransferase) (DHHB-MT) (DHHB-MTase).

AS3MT_HUMAN
θ value	0.0736092 (rank : 3)	NC score	0.171335 (rank : 4)
Query Neighborhood Hits	18	Target Neighborhood Hits	15	Shared Neighborhood Hits	7
SwissProt Accessions	Q9HBK9	Gene names	AS3MT, CYT19
Domain Architecture	No domain graphic available
Description	Arsenite methyltransferase (EC 2.1.1.137) (S-adenosyl-L- methionine:arsenic(III) methyltransferase) (Methylarsonite methyltransferase).

AS3MT_MOUSE
θ value	0.0736092 (rank : 4)	NC score	0.189986 (rank : 3)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	7
SwissProt Accessions	Q91WU5, Q9QZT1	Gene names	As3mt, Cyt19
Domain Architecture	No domain graphic available
Description	Arsenite methyltransferase (EC 2.1.1.137) (S-adenosyl-L- methionine:arsenic(III) methyltransferase) (Methylarsonite methyltransferase).

METL2_HUMAN
θ value	0.0961366 (rank : 5)	NC score	0.126573 (rank : 5)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q96IZ6, Q9H9G9, Q9NUI8, Q9P0B5	Gene names	METTL2
Domain Architecture
Description	Methyltransferase-like protein 2 (EC 2.1.1.-).

GNMT_HUMAN
θ value	0.125558 (rank : 6)	NC score	0.121548 (rank : 6)
Query Neighborhood Hits	18	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	Q14749, Q9NNZ1, Q9NS24	Gene names	GNMT
Domain Architecture	No domain graphic available
Description	Glycine N-methyltransferase (EC 2.1.1.20).

ANM3_HUMAN
θ value	0.163984 (rank : 7)	NC score	0.063401 (rank : 14)
Query Neighborhood Hits	18	Target Neighborhood Hits	31	Shared Neighborhood Hits	5
SwissProt Accessions	O60678	Gene names	PRMT3, HRMT1L3
Domain Architecture
Description	Protein arginine N-methyltransferase 3 (EC 2.1.1.-) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3).

MCES_HUMAN
θ value	0.21417 (rank : 8)	NC score	0.066352 (rank : 12)
Query Neighborhood Hits	18	Target Neighborhood Hits	134	Shared Neighborhood Hits	2
SwissProt Accessions	O43148, O94996, Q9UIJ9	Gene names	RNMT, KIAA0398
Domain Architecture	No domain graphic available
Description	mRNA cap guanine-N7 methyltransferase (EC 2.1.1.56) (mRNA (guanine- N(7)-)-methyltransferase) (RG7MT1) (mRNA cap methyltransferase) (hcm1p) (hCMT1) (hMet).

ANM3_MOUSE
θ value	0.365318 (rank : 9)	NC score	0.061311 (rank : 15)
Query Neighborhood Hits	18	Target Neighborhood Hits	30	Shared Neighborhood Hits	6
SwissProt Accessions	Q922H1, Q80VU9, Q8BFV5	Gene names	Prmt3, Hrmt1l3
Domain Architecture
Description	Protein arginine N-methyltransferase 3 (EC 2.1.1.-) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3).

MET7A_HUMAN
θ value	0.365318 (rank : 10)	NC score	0.083458 (rank : 10)
Query Neighborhood Hits	18	Target Neighborhood Hits	13	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H8H3, Q9H7R3, Q9UHZ7, Q9Y422	Gene names	METTL7A
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 7A precursor (EC 2.1.1.-) (Protein AAM- B).

PIMT_MOUSE
θ value	0.62314 (rank : 11)	NC score	0.107587 (rank : 7)
Query Neighborhood Hits	18	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	P23506, Q810R4	Gene names	Pcmt1
Domain Architecture
Description	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (EC 2.1.1.77) (Protein-beta-aspartate methyltransferase) (PIMT) (Protein L- isoaspartyl/D-aspartyl methyltransferase) (L-isoaspartyl protein carboxyl methyltransferase).

WBS27_HUMAN
θ value	3.0926 (rank : 12)	NC score	0.076138 (rank : 11)
Query Neighborhood Hits	18	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N6F8	Gene names	WBSCR27
Domain Architecture	No domain graphic available
Description	Williams-Beuren syndrome chromosome region 27 protein.

METL2_MOUSE
θ value	4.03905 (rank : 13)	NC score	0.091010 (rank : 8)
Query Neighborhood Hits	18	Target Neighborhood Hits	17	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BMK1, Q8BXC2	Gene names	Mettl2, D11Ertd768e
Domain Architecture
Description	Methyltransferase-like protein 2 (EC 2.1.1.-).

GNMT_MOUSE
θ value	5.27518 (rank : 14)	NC score	0.065685 (rank : 13)
Query Neighborhood Hits	18	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QXF8, Q91WN7	Gene names	Gnmt
Domain Architecture	No domain graphic available
Description	Glycine N-methyltransferase (EC 2.1.1.20).

K0859_HUMAN
θ value	5.27518 (rank : 15)	NC score	0.032774 (rank : 17)
Query Neighborhood Hits	18	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N6R0, O94940, Q5TGP9, Q5TGQ0, Q8N2P8, Q96J11, Q96SQ0, Q9Y2Z1, Q9Y3M6	Gene names	KIAA0859
Domain Architecture	No domain graphic available
Description	Protein KIAA0859.

PIMT_HUMAN
θ value	5.27518 (rank : 16)	NC score	0.088111 (rank : 9)
Query Neighborhood Hits	18	Target Neighborhood Hits	12	Shared Neighborhood Hits	7
SwissProt Accessions	P22061, Q14661, Q16556, Q93061, Q96II9, Q99625	Gene names	PCMT1
Domain Architecture
Description	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (EC 2.1.1.77) (Protein-beta-aspartate methyltransferase) (PIMT) (Protein L- isoaspartyl/D-aspartyl methyltransferase) (L-isoaspartyl protein carboxyl methyltransferase).

ANM6_HUMAN
θ value	8.99809 (rank : 17)	NC score	0.034374 (rank : 16)
Query Neighborhood Hits	18	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q96LA8, Q6DKI4, Q9NVR8	Gene names	PRMT6, HRMT1L6
Domain Architecture
Description	Protein arginine N-methyltransferase 6 (EC 2.1.1.-) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6).

K0859_MOUSE
θ value	8.99809 (rank : 18)	NC score	0.029098 (rank : 18)
Query Neighborhood Hits	18	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q91YR5, Q3TFY3, Q69ZX4, Q8BWN2, Q8BX81	Gene names	Kiaa0859
Domain Architecture	No domain graphic available
Description	Protein KIAA0859.

Hits sorted by NC score

COQ3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NZJ6, Q6P4F0, Q8IXG6, Q96BG1, Q9H0N1	Gene names	COQ3
Domain Architecture
Description	Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial precursor (EC 2.1.1.114) (Dihydroxyhexaprenylbenzoate methyltransferase) (3,4- dihydroxy-5-hexaprenylbenzoate methyltransferase) (DHHB methyltransferase) (DHHB-MT) (DHHB-MTase).

COQ3_MOUSE
NC score	0.987828 (rank : 2)	θ value	5.96274e-153 (rank : 2)
Query Neighborhood Hits	18	Target Neighborhood Hits	15	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BMS4, Q3TCX5, Q6P918, Q8BM28	Gene names	Coq3
Domain Architecture	No domain graphic available
Description	Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial precursor (EC 2.1.1.114) (Dihydroxyhexaprenylbenzoate methyltransferase) (3,4- dihydroxy-5-hexaprenylbenzoate methyltransferase) (DHHB methyltransferase) (DHHB-MT) (DHHB-MTase).

AS3MT_MOUSE
NC score	0.189986 (rank : 3)	θ value	0.0736092 (rank : 4)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	7
SwissProt Accessions	Q91WU5, Q9QZT1	Gene names	As3mt, Cyt19
Domain Architecture	No domain graphic available
Description	Arsenite methyltransferase (EC 2.1.1.137) (S-adenosyl-L- methionine:arsenic(III) methyltransferase) (Methylarsonite methyltransferase).

AS3MT_HUMAN
NC score	0.171335 (rank : 4)	θ value	0.0736092 (rank : 3)
Query Neighborhood Hits	18	Target Neighborhood Hits	15	Shared Neighborhood Hits	7
SwissProt Accessions	Q9HBK9	Gene names	AS3MT, CYT19
Domain Architecture	No domain graphic available
Description	Arsenite methyltransferase (EC 2.1.1.137) (S-adenosyl-L- methionine:arsenic(III) methyltransferase) (Methylarsonite methyltransferase).

METL2_HUMAN
NC score	0.126573 (rank : 5)	θ value	0.0961366 (rank : 5)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q96IZ6, Q9H9G9, Q9NUI8, Q9P0B5	Gene names	METTL2
Domain Architecture
Description	Methyltransferase-like protein 2 (EC 2.1.1.-).

GNMT_HUMAN
NC score	0.121548 (rank : 6)	θ value	0.125558 (rank : 6)
Query Neighborhood Hits	18	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	Q14749, Q9NNZ1, Q9NS24	Gene names	GNMT
Domain Architecture	No domain graphic available
Description	Glycine N-methyltransferase (EC 2.1.1.20).

PIMT_MOUSE
NC score	0.107587 (rank : 7)	θ value	0.62314 (rank : 11)
Query Neighborhood Hits	18	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	P23506, Q810R4	Gene names	Pcmt1
Domain Architecture
Description	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (EC 2.1.1.77) (Protein-beta-aspartate methyltransferase) (PIMT) (Protein L- isoaspartyl/D-aspartyl methyltransferase) (L-isoaspartyl protein carboxyl methyltransferase).

METL2_MOUSE
NC score	0.091010 (rank : 8)	θ value	4.03905 (rank : 13)
Query Neighborhood Hits	18	Target Neighborhood Hits	17	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BMK1, Q8BXC2	Gene names	Mettl2, D11Ertd768e
Domain Architecture
Description	Methyltransferase-like protein 2 (EC 2.1.1.-).

PIMT_HUMAN
NC score	0.088111 (rank : 9)	θ value	5.27518 (rank : 16)
Query Neighborhood Hits	18	Target Neighborhood Hits	12	Shared Neighborhood Hits	7
SwissProt Accessions	P22061, Q14661, Q16556, Q93061, Q96II9, Q99625	Gene names	PCMT1
Domain Architecture
Description	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (EC 2.1.1.77) (Protein-beta-aspartate methyltransferase) (PIMT) (Protein L- isoaspartyl/D-aspartyl methyltransferase) (L-isoaspartyl protein carboxyl methyltransferase).

MET7A_HUMAN
NC score	0.083458 (rank : 10)	θ value	0.365318 (rank : 10)
Query Neighborhood Hits	18	Target Neighborhood Hits	13	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H8H3, Q9H7R3, Q9UHZ7, Q9Y422	Gene names	METTL7A
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 7A precursor (EC 2.1.1.-) (Protein AAM- B).

WBS27_HUMAN
NC score	0.076138 (rank : 11)	θ value	3.0926 (rank : 12)
Query Neighborhood Hits	18	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N6F8	Gene names	WBSCR27
Domain Architecture	No domain graphic available
Description	Williams-Beuren syndrome chromosome region 27 protein.

MCES_HUMAN
NC score	0.066352 (rank : 12)	θ value	0.21417 (rank : 8)
Query Neighborhood Hits	18	Target Neighborhood Hits	134	Shared Neighborhood Hits	2
SwissProt Accessions	O43148, O94996, Q9UIJ9	Gene names	RNMT, KIAA0398
Domain Architecture	No domain graphic available
Description	mRNA cap guanine-N7 methyltransferase (EC 2.1.1.56) (mRNA (guanine- N(7)-)-methyltransferase) (RG7MT1) (mRNA cap methyltransferase) (hcm1p) (hCMT1) (hMet).

GNMT_MOUSE
NC score	0.065685 (rank : 13)	θ value	5.27518 (rank : 14)
Query Neighborhood Hits	18	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QXF8, Q91WN7	Gene names	Gnmt
Domain Architecture	No domain graphic available
Description	Glycine N-methyltransferase (EC 2.1.1.20).

ANM3_HUMAN
NC score	0.063401 (rank : 14)	θ value	0.163984 (rank : 7)
Query Neighborhood Hits	18	Target Neighborhood Hits	31	Shared Neighborhood Hits	5
SwissProt Accessions	O60678	Gene names	PRMT3, HRMT1L3
Domain Architecture
Description	Protein arginine N-methyltransferase 3 (EC 2.1.1.-) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3).

ANM3_MOUSE
NC score	0.061311 (rank : 15)	θ value	0.365318 (rank : 9)
Query Neighborhood Hits	18	Target Neighborhood Hits	30	Shared Neighborhood Hits	6
SwissProt Accessions	Q922H1, Q80VU9, Q8BFV5	Gene names	Prmt3, Hrmt1l3
Domain Architecture
Description	Protein arginine N-methyltransferase 3 (EC 2.1.1.-) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3).

ANM6_HUMAN
NC score	0.034374 (rank : 16)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	18	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q96LA8, Q6DKI4, Q9NVR8	Gene names	PRMT6, HRMT1L6
Domain Architecture
Description	Protein arginine N-methyltransferase 6 (EC 2.1.1.-) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6).

K0859_HUMAN
NC score	0.032774 (rank : 17)	θ value	5.27518 (rank : 15)
Query Neighborhood Hits	18	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N6R0, O94940, Q5TGP9, Q5TGQ0, Q8N2P8, Q96J11, Q96SQ0, Q9Y2Z1, Q9Y3M6	Gene names	KIAA0859
Domain Architecture	No domain graphic available
Description	Protein KIAA0859.

K0859_MOUSE
NC score	0.029098 (rank : 18)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	18	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q91YR5, Q3TFY3, Q69ZX4, Q8BWN2, Q8BX81	Gene names	Kiaa0859
Domain Architecture	No domain graphic available
Description	Protein KIAA0859.