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Network neighborhood for query Sequence : AS3MT_HUMAN

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AS3MT_HUMAN
SwissProt Accessions	Q9HBK9	Gene names	AS3MT, CYT19
Domain Architecture	No domain graphic available
Description	Arsenite methyltransferase (EC 2.1.1.137) (S-adenosyl-L- methionine:arsenic(III) methyltransferase) (Methylarsonite methyltransferase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

AS3MT_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	Q9HBK9	Gene names	AS3MT, CYT19
Domain Architecture	No domain graphic available
Description	Arsenite methyltransferase (EC 2.1.1.137) (S-adenosyl-L- methionine:arsenic(III) methyltransferase) (Methylarsonite methyltransferase).

AS3MT_MOUSE
θ value	1.15563e-172 (rank : 2)	NC score	0.993277 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	Q91WU5, Q9QZT1	Gene names	As3mt, Cyt19
Domain Architecture	No domain graphic available
Description	Arsenite methyltransferase (EC 2.1.1.137) (S-adenosyl-L- methionine:arsenic(III) methyltransferase) (Methylarsonite methyltransferase).

MET7B_MOUSE
θ value	0.0252991 (rank : 3)	NC score	0.179894 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	Q9DD20, Q78ID2	Gene names	Mettl7b
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 7B precursor (EC 2.1.1.-).

COQ3_MOUSE
θ value	0.0431538 (rank : 4)	NC score	0.197507 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BMS4, Q3TCX5, Q6P918, Q8BM28	Gene names	Coq3
Domain Architecture	No domain graphic available
Description	Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial precursor (EC 2.1.1.114) (Dihydroxyhexaprenylbenzoate methyltransferase) (3,4- dihydroxy-5-hexaprenylbenzoate methyltransferase) (DHHB methyltransferase) (DHHB-MT) (DHHB-MTase).

COQ3_HUMAN
θ value	0.0736092 (rank : 5)	NC score	0.171335 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	18	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NZJ6, Q6P4F0, Q8IXG6, Q96BG1, Q9H0N1	Gene names	COQ3
Domain Architecture
Description	Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial precursor (EC 2.1.1.114) (Dihydroxyhexaprenylbenzoate methyltransferase) (3,4- dihydroxy-5-hexaprenylbenzoate methyltransferase) (DHHB methyltransferase) (DHHB-MT) (DHHB-MTase).

MET7A_HUMAN
θ value	0.279714 (rank : 6)	NC score	0.157284 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H8H3, Q9H7R3, Q9UHZ7, Q9Y422	Gene names	METTL7A
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 7A precursor (EC 2.1.1.-) (Protein AAM- B).

MET7B_HUMAN
θ value	0.813845 (rank : 7)	NC score	0.146171 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q6UX53, Q8WUI1	Gene names	METTL7B
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 7B precursor (EC 2.1.1.-).

PIMT_MOUSE
θ value	1.06291 (rank : 8)	NC score	0.098709 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	13	Shared Neighborhood Hits	6
SwissProt Accessions	P23506, Q810R4	Gene names	Pcmt1
Domain Architecture
Description	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (EC 2.1.1.77) (Protein-beta-aspartate methyltransferase) (PIMT) (Protein L- isoaspartyl/D-aspartyl methyltransferase) (L-isoaspartyl protein carboxyl methyltransferase).

CPIN1_HUMAN
θ value	1.38821 (rank : 9)	NC score	0.053264 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	17	Shared Neighborhood Hits	5
SwissProt Accessions	Q6FI81, O75206, O75207, Q9H0W1, Q9P1L7	Gene names	CIAPIN1
Domain Architecture	No domain graphic available
Description	Anamorsin (Cytokine-induced apoptosis inhibitor 1) (CUA001).

PIMT_HUMAN
θ value	4.03905 (rank : 10)	NC score	0.077755 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	P22061, Q14661, Q16556, Q93061, Q96II9, Q99625	Gene names	PCMT1
Domain Architecture
Description	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (EC 2.1.1.77) (Protein-beta-aspartate methyltransferase) (PIMT) (Protein L- isoaspartyl/D-aspartyl methyltransferase) (L-isoaspartyl protein carboxyl methyltransferase).

HUCE1_MOUSE
θ value	5.27518 (rank : 11)	NC score	0.037181 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	65	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DB85, Q8BHW3	Gene names
Domain Architecture	No domain graphic available
Description	Cerebral protein 1 homolog.

HUCE1_HUMAN
θ value	6.88961 (rank : 12)	NC score	0.037966 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	O43159, Q7KZ78, Q9BVM6	Gene names	KIAA0409
Domain Architecture	No domain graphic available
Description	Cerebral protein 1.

MACF1_HUMAN
θ value	6.88961 (rank : 13)	NC score	0.008024 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	1341	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF4_HUMAN
θ value	6.88961 (rank : 14)	NC score	0.009352 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	1321	Shared Neighborhood Hits	3
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

ENPP2_MOUSE
θ value	8.99809 (rank : 15)	NC score	0.009580 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	66	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R1E6, Q99LG9	Gene names	Enpp2, Npps2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

Hits sorted by NC score

AS3MT_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	Q9HBK9	Gene names	AS3MT, CYT19
Domain Architecture	No domain graphic available
Description	Arsenite methyltransferase (EC 2.1.1.137) (S-adenosyl-L- methionine:arsenic(III) methyltransferase) (Methylarsonite methyltransferase).

AS3MT_MOUSE
NC score	0.993277 (rank : 2)	θ value	1.15563e-172 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	Q91WU5, Q9QZT1	Gene names	As3mt, Cyt19
Domain Architecture	No domain graphic available
Description	Arsenite methyltransferase (EC 2.1.1.137) (S-adenosyl-L- methionine:arsenic(III) methyltransferase) (Methylarsonite methyltransferase).

COQ3_MOUSE
NC score	0.197507 (rank : 3)	θ value	0.0431538 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BMS4, Q3TCX5, Q6P918, Q8BM28	Gene names	Coq3
Domain Architecture	No domain graphic available
Description	Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial precursor (EC 2.1.1.114) (Dihydroxyhexaprenylbenzoate methyltransferase) (3,4- dihydroxy-5-hexaprenylbenzoate methyltransferase) (DHHB methyltransferase) (DHHB-MT) (DHHB-MTase).

MET7B_MOUSE
NC score	0.179894 (rank : 4)	θ value	0.0252991 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	Q9DD20, Q78ID2	Gene names	Mettl7b
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 7B precursor (EC 2.1.1.-).

COQ3_HUMAN
NC score	0.171335 (rank : 5)	θ value	0.0736092 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	18	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NZJ6, Q6P4F0, Q8IXG6, Q96BG1, Q9H0N1	Gene names	COQ3
Domain Architecture
Description	Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial precursor (EC 2.1.1.114) (Dihydroxyhexaprenylbenzoate methyltransferase) (3,4- dihydroxy-5-hexaprenylbenzoate methyltransferase) (DHHB methyltransferase) (DHHB-MT) (DHHB-MTase).

MET7A_HUMAN
NC score	0.157284 (rank : 6)	θ value	0.279714 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H8H3, Q9H7R3, Q9UHZ7, Q9Y422	Gene names	METTL7A
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 7A precursor (EC 2.1.1.-) (Protein AAM- B).

MET7B_HUMAN
NC score	0.146171 (rank : 7)	θ value	0.813845 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q6UX53, Q8WUI1	Gene names	METTL7B
Domain Architecture	No domain graphic available
Description	Methyltransferase-like protein 7B precursor (EC 2.1.1.-).

PIMT_MOUSE
NC score	0.098709 (rank : 8)	θ value	1.06291 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	13	Shared Neighborhood Hits	6
SwissProt Accessions	P23506, Q810R4	Gene names	Pcmt1
Domain Architecture
Description	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (EC 2.1.1.77) (Protein-beta-aspartate methyltransferase) (PIMT) (Protein L- isoaspartyl/D-aspartyl methyltransferase) (L-isoaspartyl protein carboxyl methyltransferase).

PIMT_HUMAN
NC score	0.077755 (rank : 9)	θ value	4.03905 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	P22061, Q14661, Q16556, Q93061, Q96II9, Q99625	Gene names	PCMT1
Domain Architecture
Description	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (EC 2.1.1.77) (Protein-beta-aspartate methyltransferase) (PIMT) (Protein L- isoaspartyl/D-aspartyl methyltransferase) (L-isoaspartyl protein carboxyl methyltransferase).

CPIN1_HUMAN
NC score	0.053264 (rank : 10)	θ value	1.38821 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	17	Shared Neighborhood Hits	5
SwissProt Accessions	Q6FI81, O75206, O75207, Q9H0W1, Q9P1L7	Gene names	CIAPIN1
Domain Architecture	No domain graphic available
Description	Anamorsin (Cytokine-induced apoptosis inhibitor 1) (CUA001).

HUCE1_HUMAN
NC score	0.037966 (rank : 11)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	O43159, Q7KZ78, Q9BVM6	Gene names	KIAA0409
Domain Architecture	No domain graphic available
Description	Cerebral protein 1.

HUCE1_MOUSE
NC score	0.037181 (rank : 12)	θ value	5.27518 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	65	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DB85, Q8BHW3	Gene names
Domain Architecture	No domain graphic available
Description	Cerebral protein 1 homolog.

ENPP2_MOUSE
NC score	0.009580 (rank : 13)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	66	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R1E6, Q99LG9	Gene names	Enpp2, Npps2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

MACF4_HUMAN
NC score	0.009352 (rank : 14)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	1321	Shared Neighborhood Hits	3
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MACF1_HUMAN
NC score	0.008024 (rank : 15)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	1341	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).