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Network neighborhood for query Sequence : NEUL_HUMAN

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NEUL_HUMAN
SwissProt Accessions	Q9BYT8, Q9ULJ4	Gene names	NLN, KIAA1226
Domain Architecture
Description	Neurolysin, mitochondrial precursor (EC 3.4.24.16) (Neurotensin endopeptidase) (Mitochondrial oligopeptidase M) (Microsomal endopeptidase) (MEP).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MEPD_HUMAN
θ value	0 (rank : 1)	NC score	0.976795 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	39	Shared Neighborhood Hits	5
SwissProt Accessions	P52888, Q9UCB3	Gene names	THOP1
Domain Architecture
Description	Thimet oligopeptidase (EC 3.4.24.15) (Endopeptidase 24.15) (MP78).

NEUL_HUMAN
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BYT8, Q9ULJ4	Gene names	NLN, KIAA1226
Domain Architecture
Description	Neurolysin, mitochondrial precursor (EC 3.4.24.16) (Neurotensin endopeptidase) (Mitochondrial oligopeptidase M) (Microsomal endopeptidase) (MEP).

PMIP_HUMAN
θ value	3.72821e-46 (rank : 3)	NC score	0.811488 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q99797	Gene names	MIPEP, MIP
Domain Architecture
Description	Mitochondrial intermediate peptidase, mitochondrial precursor (EC 3.4.24.59) (MIP).

CE290_HUMAN
θ value	0.0431538 (rank : 4)	NC score	0.031279 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	1553	Shared Neighborhood Hits	8
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

SYCP1_MOUSE
θ value	0.163984 (rank : 5)	NC score	0.029949 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	1456	Shared Neighborhood Hits	10
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

CI039_HUMAN
θ value	0.47712 (rank : 6)	NC score	0.026445 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	1171	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

REST_HUMAN
θ value	1.06291 (rank : 7)	NC score	0.017304 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	1605	Shared Neighborhood Hits	10
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

AKAP9_HUMAN
θ value	1.38821 (rank : 8)	NC score	0.025833 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	1710	Shared Neighborhood Hits	9
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

CI093_HUMAN
θ value	2.36792 (rank : 9)	NC score	0.019621 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	1088	Shared Neighborhood Hits	8
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

BPNT1_MOUSE
θ value	3.0926 (rank : 10)	NC score	0.027733 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z0S1, Q3U8Z5, Q91XB9, Q9D7Y0	Gene names	Bpnt1
Domain Architecture
Description	3'(2'),5'-bisphosphate nucleotidase 1 (EC 3.1.3.7) (Bisphosphate 3'- nucleotidase 1) (PAP-inositol-1,4-phosphatase) (PIP).

MAD4_MOUSE
θ value	3.0926 (rank : 11)	NC score	0.022153 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	65	Shared Neighborhood Hits	2
SwissProt Accessions	Q60948	Gene names	Mxd4, Mad4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

POLK_MOUSE
θ value	4.03905 (rank : 12)	NC score	0.020539 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	66	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QUG2, Q7TPY7	Gene names	Polk, Dinb1
Domain Architecture	No domain graphic available
Description	DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP).

TAP2_MOUSE
θ value	4.03905 (rank : 13)	NC score	0.010755 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	93	Shared Neighborhood Hits	3
SwissProt Accessions	P36371	Gene names	Tap2, Abcb3, Ham-2, Ham2
Domain Architecture
Description	Antigen peptide transporter 2 (APT2) (ATP-binding cassette sub-family B member 3) (Histocompatibility antigen modifier 2).

WNK3_HUMAN
θ value	4.03905 (rank : 14)	NC score	0.003970 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	948	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BYP7, Q9HCK6	Gene names	WNK3, KIAA1566, PRKWNK3
Domain Architecture
Description	Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3).

PDC6I_MOUSE
θ value	5.27518 (rank : 15)	NC score	0.016035 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	275	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

MK13_MOUSE
θ value	6.88961 (rank : 16)	NC score	0.001308 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	832	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z1B7, Q99M57	Gene names	Mapk13, Serk4
Domain Architecture
Description	Mitogen-activated protein kinase 13 (EC 2.7.11.24) (Stress-activated protein kinase 4) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta).

TAP1_MOUSE
θ value	6.88961 (rank : 17)	NC score	0.009609 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	95	Shared Neighborhood Hits	3
SwissProt Accessions	P21958	Gene names	Tap1, Abcb2, Ham-1, Ham1
Domain Architecture
Description	Antigen peptide transporter 1 (APT1) (Peptide transporter TAP1) (ATP- binding cassette sub-family B member 2) (Histocompatibility antigen modifier 1).

HCD2_MOUSE
θ value	8.99809 (rank : 18)	NC score	0.010096 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	65	Shared Neighborhood Hits	2
SwissProt Accessions	O08756	Gene names	Hadh2, Erab, Hsd17b10
Domain Architecture
Description	3-hydroxyacyl-CoA dehydrogenase type-2 (EC 1.1.1.35) (3-hydroxyacyl- CoA dehydrogenase type II) (Type II HADH) (3-hydroxy-2-methylbutyryl- CoA dehydrogenase) (EC 1.1.1.178) (Endoplasmic reticulum-associated amyloid beta-peptide-binding protein).

SDCG8_MOUSE
θ value	8.99809 (rank : 19)	NC score	0.015082 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	886	Shared Neighborhood Hits	8
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

Hits sorted by NC score

NEUL_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BYT8, Q9ULJ4	Gene names	NLN, KIAA1226
Domain Architecture
Description	Neurolysin, mitochondrial precursor (EC 3.4.24.16) (Neurotensin endopeptidase) (Mitochondrial oligopeptidase M) (Microsomal endopeptidase) (MEP).

MEPD_HUMAN
NC score	0.976795 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	39	Shared Neighborhood Hits	5
SwissProt Accessions	P52888, Q9UCB3	Gene names	THOP1
Domain Architecture
Description	Thimet oligopeptidase (EC 3.4.24.15) (Endopeptidase 24.15) (MP78).

PMIP_HUMAN
NC score	0.811488 (rank : 3)	θ value	3.72821e-46 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q99797	Gene names	MIPEP, MIP
Domain Architecture
Description	Mitochondrial intermediate peptidase, mitochondrial precursor (EC 3.4.24.59) (MIP).

CE290_HUMAN
NC score	0.031279 (rank : 4)	θ value	0.0431538 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	1553	Shared Neighborhood Hits	8
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

SYCP1_MOUSE
NC score	0.029949 (rank : 5)	θ value	0.163984 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	1456	Shared Neighborhood Hits	10
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

BPNT1_MOUSE
NC score	0.027733 (rank : 6)	θ value	3.0926 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z0S1, Q3U8Z5, Q91XB9, Q9D7Y0	Gene names	Bpnt1
Domain Architecture
Description	3'(2'),5'-bisphosphate nucleotidase 1 (EC 3.1.3.7) (Bisphosphate 3'- nucleotidase 1) (PAP-inositol-1,4-phosphatase) (PIP).

CI039_HUMAN
NC score	0.026445 (rank : 7)	θ value	0.47712 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	1171	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

AKAP9_HUMAN
NC score	0.025833 (rank : 8)	θ value	1.38821 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	1710	Shared Neighborhood Hits	9
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

MAD4_MOUSE
NC score	0.022153 (rank : 9)	θ value	3.0926 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	65	Shared Neighborhood Hits	2
SwissProt Accessions	Q60948	Gene names	Mxd4, Mad4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

POLK_MOUSE
NC score	0.020539 (rank : 10)	θ value	4.03905 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	66	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QUG2, Q7TPY7	Gene names	Polk, Dinb1
Domain Architecture	No domain graphic available
Description	DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP).

CI093_HUMAN
NC score	0.019621 (rank : 11)	θ value	2.36792 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	1088	Shared Neighborhood Hits	8
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

REST_HUMAN
NC score	0.017304 (rank : 12)	θ value	1.06291 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	1605	Shared Neighborhood Hits	10
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

PDC6I_MOUSE
NC score	0.016035 (rank : 13)	θ value	5.27518 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	275	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

SDCG8_MOUSE
NC score	0.015082 (rank : 14)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	886	Shared Neighborhood Hits	8
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

TAP2_MOUSE
NC score	0.010755 (rank : 15)	θ value	4.03905 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	93	Shared Neighborhood Hits	3
SwissProt Accessions	P36371	Gene names	Tap2, Abcb3, Ham-2, Ham2
Domain Architecture
Description	Antigen peptide transporter 2 (APT2) (ATP-binding cassette sub-family B member 3) (Histocompatibility antigen modifier 2).

HCD2_MOUSE
NC score	0.010096 (rank : 16)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	65	Shared Neighborhood Hits	2
SwissProt Accessions	O08756	Gene names	Hadh2, Erab, Hsd17b10
Domain Architecture
Description	3-hydroxyacyl-CoA dehydrogenase type-2 (EC 1.1.1.35) (3-hydroxyacyl- CoA dehydrogenase type II) (Type II HADH) (3-hydroxy-2-methylbutyryl- CoA dehydrogenase) (EC 1.1.1.178) (Endoplasmic reticulum-associated amyloid beta-peptide-binding protein).

TAP1_MOUSE
NC score	0.009609 (rank : 17)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	95	Shared Neighborhood Hits	3
SwissProt Accessions	P21958	Gene names	Tap1, Abcb2, Ham-1, Ham1
Domain Architecture
Description	Antigen peptide transporter 1 (APT1) (Peptide transporter TAP1) (ATP- binding cassette sub-family B member 2) (Histocompatibility antigen modifier 1).

WNK3_HUMAN
NC score	0.003970 (rank : 18)	θ value	4.03905 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	948	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BYP7, Q9HCK6	Gene names	WNK3, KIAA1566, PRKWNK3
Domain Architecture
Description	Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3).

MK13_MOUSE
NC score	0.001308 (rank : 19)	θ value	6.88961 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	832	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z1B7, Q99M57	Gene names	Mapk13, Serk4
Domain Architecture
Description	Mitogen-activated protein kinase 13 (EC 2.7.11.24) (Stress-activated protein kinase 4) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta).