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Network neighborhood for query Sequence : HMGB1_HUMAN

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HMGB1_HUMAN
SwissProt Accessions	P09429, Q6IBE1	Gene names	HMGB1, HMG1
Domain Architecture
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HMGB1_HUMAN
θ value	8.77142e-88 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	126	Target Neighborhood Hits	126	Shared Neighborhood Hits	126
SwissProt Accessions	P09429, Q6IBE1	Gene names	HMGB1, HMG1
Domain Architecture
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

HMGB1_MOUSE
θ value	8.77142e-88 (rank : 2)	NC score	0.999109 (rank : 2)
Query Neighborhood Hits	126	Target Neighborhood Hits	123	Shared Neighborhood Hits	117
SwissProt Accessions	P63158, P07155, P27109, P27428	Gene names	Hmgb1, Hmg-1, Hmg1
Domain Architecture	No domain graphic available
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

HMGB2_HUMAN
θ value	9.39325e-82 (rank : 3)	NC score	0.987107 (rank : 5)
Query Neighborhood Hits	126	Target Neighborhood Hits	114	Shared Neighborhood Hits	87
SwissProt Accessions	P26583	Gene names	HMGB2, HMG2
Domain Architecture
Description	High mobility group protein B2 (High mobility group protein 2) (HMG- 2).

HMG1X_HUMAN
θ value	6.08852e-81 (rank : 4)	NC score	0.992942 (rank : 3)
Query Neighborhood Hits	126	Target Neighborhood Hits	97	Shared Neighborhood Hits	95
SwissProt Accessions	Q9UGV6	Gene names	HMG1L10
Domain Architecture
Description	High mobility group protein 1-like 10 (HMG-1L10).

HMGB2_MOUSE
θ value	1.77149e-80 (rank : 5)	NC score	0.987914 (rank : 4)
Query Neighborhood Hits	126	Target Neighborhood Hits	111	Shared Neighborhood Hits	87
SwissProt Accessions	P30681, Q3UXT1, Q9EQD5	Gene names	Hmgb2, Hmg2
Domain Architecture
Description	High mobility group protein B2 (High mobility group protein 2) (HMG- 2).

HMGB3_MOUSE
θ value	2.74572e-65 (rank : 6)	NC score	0.976476 (rank : 6)
Query Neighborhood Hits	126	Target Neighborhood Hits	88	Shared Neighborhood Hits	77
SwissProt Accessions	O54879	Gene names	Hmgb3, Hmg2a, Hmg4
Domain Architecture
Description	High mobility group protein B3 (High mobility group protein 4) (HMG-4) (High mobility group protein 2a) (HMG-2a).

HMGB3_HUMAN
θ value	1.04338e-64 (rank : 7)	NC score	0.974826 (rank : 7)
Query Neighborhood Hits	126	Target Neighborhood Hits	86	Shared Neighborhood Hits	76
SwissProt Accessions	O15347, O95556, Q6NS40	Gene names	HMGB3, HMG2A, HMG4
Domain Architecture
Description	High mobility group protein B3 (High mobility group protein 4) (HMG-4) (High mobility group protein 2a) (HMG-2a).

SP100_HUMAN
θ value	1.84173e-61 (rank : 8)	NC score	0.800974 (rank : 8)
Query Neighborhood Hits	126	Target Neighborhood Hits	117	Shared Neighborhood Hits	69
SwissProt Accessions	P23497, O75450, Q13343, Q96F70, Q96T24, Q96T95, Q9NP33, Q9UE32	Gene names	SP100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein) (Lysp100b).

SSRP1_HUMAN
θ value	2.60593e-15 (rank : 9)	NC score	0.735730 (rank : 9)
Query Neighborhood Hits	126	Target Neighborhood Hits	187	Shared Neighborhood Hits	87
SwissProt Accessions	Q08945, Q5BJG8	Gene names	SSRP1, FACT80
Domain Architecture
Description	FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (FACT 80 kDa subunit) (FACTp80) (Chromatin- specific transcription elongation factor 80 kDa subunit) (Structure- specific recognition protein 1) (hSSRP1) (Recombination signal sequence recognition protein 1) (T160).

SSRP1_MOUSE
θ value	3.76295e-14 (rank : 10)	NC score	0.726542 (rank : 10)
Query Neighborhood Hits	126	Target Neighborhood Hits	193	Shared Neighborhood Hits	91
SwissProt Accessions	Q08943, Q3U9Z2, Q3UJ75, Q4V9U4, Q8CGA6	Gene names	Ssrp1
Domain Architecture
Description	FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (Structure-specific recognition protein 1) (Recombination signal sequence recognition protein 1) (T160).

TOX_MOUSE
θ value	7.34386e-10 (rank : 11)	NC score	0.573673 (rank : 18)
Query Neighborhood Hits	126	Target Neighborhood Hits	95	Shared Neighborhood Hits	55
SwissProt Accessions	Q66JW3, Q8BKH9, Q8BYQ5, Q8R4H0	Gene names	Tox
Domain Architecture	No domain graphic available
Description	Thymus high mobility group box protein TOX.

TOX_HUMAN
θ value	9.59137e-10 (rank : 12)	NC score	0.569325 (rank : 19)
Query Neighborhood Hits	126	Target Neighborhood Hits	106	Shared Neighborhood Hits	55
SwissProt Accessions	O94900, Q96AV5	Gene names	TOX, KIAA0808
Domain Architecture	No domain graphic available
Description	Thymus high mobility group box protein TOX.

HM20B_MOUSE
θ value	1.25267e-09 (rank : 13)	NC score	0.685974 (rank : 11)
Query Neighborhood Hits	126	Target Neighborhood Hits	122	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Z104, Q9NSF7, Q9NSF8	Gene names	Hmg20b, Braf35, Hmgx2, Smarce1r
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (HMG domain protein HMG20B) (Structural DNA-binding protein BRAF35) (BRCA2- associated factor 35).

HM20A_HUMAN
θ value	2.13673e-09 (rank : 14)	NC score	0.603894 (rank : 15)
Query Neighborhood Hits	126	Target Neighborhood Hits	343	Shared Neighborhood Hits	79
SwissProt Accessions	Q9NP66, Q53G31, Q9NSF6	Gene names	HMG20A, HMGX1
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein HMGX1).

HM20A_MOUSE
θ value	2.13673e-09 (rank : 15)	NC score	0.602260 (rank : 16)
Query Neighborhood Hits	126	Target Neighborhood Hits	348	Shared Neighborhood Hits	79
SwissProt Accessions	Q9DC33, Q3LSF9, Q6NV87, Q8BSK1, Q8C3C1, Q8CAA0, Q9CYG2	Gene names	Hmg20a, Ibraf
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (iBRAF) (Inhibitor of BRAF35) (HMG domain protein HMGX1).

GCX1_HUMAN
θ value	1.38499e-08 (rank : 16)	NC score	0.509847 (rank : 42)
Query Neighborhood Hits	126	Target Neighborhood Hits	132	Shared Neighborhood Hits	55
SwissProt Accessions	Q96NM4, Q5TE33, Q5TE34, Q5TE35, Q96IC9, Q9BQN5	Gene names	GCX1, C20orf100
Domain Architecture
Description	Granulosa cell HMG box protein 1 (GCX-1).

TFAM_HUMAN
θ value	4.0297e-08 (rank : 17)	NC score	0.596352 (rank : 17)
Query Neighborhood Hits	126	Target Neighborhood Hits	156	Shared Neighborhood Hits	67
SwissProt Accessions	Q00059	Gene names	TFAM, TCF6L2
Domain Architecture
Description	Transcription factor A, mitochondrial precursor (mtTFA) (Mitochondrial transcription factor 1) (MtTF1) (Transcription factor 6-like 2).

CN092_MOUSE
θ value	5.26297e-08 (rank : 18)	NC score	0.558740 (rank : 21)
Query Neighborhood Hits	126	Target Neighborhood Hits	206	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BU11, Q80UI2, Q99PN9, Q9CS16	Gene names
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

HM20B_HUMAN
θ value	5.26297e-08 (rank : 19)	NC score	0.671960 (rank : 12)
Query Neighborhood Hits	126	Target Neighborhood Hits	126	Shared Neighborhood Hits	79
SwissProt Accessions	Q9P0W2, Q6IBP8, Q8NBD5, Q9HD21, Q9Y491, Q9Y4A2	Gene names	HMG20B, BRAF35, HMGX2, SMARCE1R
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (HMG domain protein HMG20B) (Structural DNA-binding protein BRAF35) (BRCA2- associated factor 35) (Sox-like transcriptional factor).

CN092_HUMAN
θ value	6.87365e-08 (rank : 20)	NC score	0.568900 (rank : 20)
Query Neighborhood Hits	126	Target Neighborhood Hits	143	Shared Neighborhood Hits	65
SwissProt Accessions	O94842	Gene names	C14orf92, KIAA0737
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

HM2L1_HUMAN
θ value	1.53129e-07 (rank : 21)	NC score	0.654562 (rank : 13)
Query Neighborhood Hits	126	Target Neighborhood Hits	130	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UGU5, O75672, O75673, Q9UMT5	Gene names	HMG2L1, HMGBCG
Domain Architecture
Description	High mobility group protein 2-like 1 (Protein HMGBCG).

UBF1_HUMAN
θ value	5.81887e-07 (rank : 22)	NC score	0.542097 (rank : 22)
Query Neighborhood Hits	126	Target Neighborhood Hits	415	Shared Neighborhood Hits	102
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

TFAM_MOUSE
θ value	7.59969e-07 (rank : 23)	NC score	0.625013 (rank : 14)
Query Neighborhood Hits	126	Target Neighborhood Hits	93	Shared Neighborhood Hits	76
SwissProt Accessions	P40630, P97894, P97906, Q543I8, Q9DBM9	Gene names	Tfam, Hmgts
Domain Architecture
Description	Transcription factor A, mitochondrial precursor (mtTFA) (Testis- specific high mobility group protein) (TS-HMG).

UBF1_MOUSE
θ value	7.59969e-07 (rank : 24)	NC score	0.531558 (rank : 25)
Query Neighborhood Hits	126	Target Neighborhood Hits	419	Shared Neighborhood Hits	100
SwissProt Accessions	P25976	Gene names	Ubtf, Tcfubf, Ubf-1, Ubf1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1).

PMS1_HUMAN
θ value	6.43352e-06 (rank : 25)	NC score	0.393637 (rank : 72)
Query Neighborhood Hits	126	Target Neighborhood Hits	126	Shared Neighborhood Hits	69
SwissProt Accessions	P54277	Gene names	PMS1, PMSL1
Domain Architecture
Description	PMS1 protein homolog 1 (DNA mismatch repair protein PMS1).

SOX10_HUMAN
θ value	6.43352e-06 (rank : 26)	NC score	0.507600 (rank : 49)
Query Neighborhood Hits	126	Target Neighborhood Hits	122	Shared Neighborhood Hits	71
SwissProt Accessions	P56693	Gene names	SOX10
Domain Architecture
Description	Transcription factor SOX-10.

SOX10_MOUSE
θ value	6.43352e-06 (rank : 27)	NC score	0.508133 (rank : 48)
Query Neighborhood Hits	126	Target Neighborhood Hits	110	Shared Neighborhood Hits	71
SwissProt Accessions	Q04888, O08518, O09141, O54856, P70416	Gene names	Sox10, Sox-10, Sox21
Domain Architecture
Description	Transcription factor SOX-10 (SOX-21) (Transcription factor SOX-M).

SOX8_HUMAN
θ value	1.09739e-05 (rank : 28)	NC score	0.532764 (rank : 23)
Query Neighborhood Hits	126	Target Neighborhood Hits	100	Shared Neighborhood Hits	75
SwissProt Accessions	P57073, Q9NZW2	Gene names	SOX8
Domain Architecture
Description	Transcription factor SOX-8.

SOX8_MOUSE
θ value	1.09739e-05 (rank : 29)	NC score	0.532366 (rank : 24)
Query Neighborhood Hits	126	Target Neighborhood Hits	96	Shared Neighborhood Hits	75
SwissProt Accessions	Q04886	Gene names	Sox8, Sox-8
Domain Architecture
Description	Transcription factor SOX-8.

SOX9_HUMAN
θ value	1.43324e-05 (rank : 30)	NC score	0.513132 (rank : 41)
Query Neighborhood Hits	126	Target Neighborhood Hits	210	Shared Neighborhood Hits	76
SwissProt Accessions	P48436	Gene names	SOX9
Domain Architecture
Description	Transcription factor SOX-9.

SOX9_MOUSE
θ value	1.43324e-05 (rank : 31)	NC score	0.514405 (rank : 39)
Query Neighborhood Hits	126	Target Neighborhood Hits	188	Shared Neighborhood Hits	76
SwissProt Accessions	Q04887, Q8C7L2, Q91ZK2, Q99KQ0	Gene names	Sox9, Sox-9
Domain Architecture
Description	Transcription factor SOX-9.

BBX_HUMAN
θ value	1.87187e-05 (rank : 32)	NC score	0.508246 (rank : 47)
Query Neighborhood Hits	126	Target Neighborhood Hits	167	Shared Neighborhood Hits	78
SwissProt Accessions	Q8WY36, Q2TAJ1, Q7L3J8, Q7LBY8, Q8NDB0, Q8WY35, Q9H0J6	Gene names	BBX, HBP2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

BBX_MOUSE
θ value	4.1701e-05 (rank : 33)	NC score	0.509577 (rank : 44)
Query Neighborhood Hits	126	Target Neighborhood Hits	152	Shared Neighborhood Hits	79
SwissProt Accessions	Q8VBW5, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VI48, Q8VI49, Q8VI50, Q9CS94	Gene names	Bbx, Hbp2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

SOX18_HUMAN
θ value	4.1701e-05 (rank : 34)	NC score	0.529170 (rank : 27)
Query Neighborhood Hits	126	Target Neighborhood Hits	106	Shared Neighborhood Hits	75
SwissProt Accessions	P35713, Q9NPH8	Gene names	SOX18
Domain Architecture
Description	Transcription factor SOX-18.

SOX2_HUMAN
θ value	7.1131e-05 (rank : 35)	NC score	0.523460 (rank : 30)
Query Neighborhood Hits	126	Target Neighborhood Hits	89	Shared Neighborhood Hits	80
SwissProt Accessions	P48431, Q14537	Gene names	SOX2
Domain Architecture
Description	Transcription factor SOX-2.

SOX2_MOUSE
θ value	7.1131e-05 (rank : 36)	NC score	0.523533 (rank : 29)
Query Neighborhood Hits	126	Target Neighborhood Hits	90	Shared Neighborhood Hits	80
SwissProt Accessions	P48432	Gene names	Sox2, Sox-2
Domain Architecture
Description	Transcription factor SOX-2.

SOX7_MOUSE
θ value	0.000158464 (rank : 37)	NC score	0.521934 (rank : 33)
Query Neighborhood Hits	126	Target Neighborhood Hits	105	Shared Neighborhood Hits	79
SwissProt Accessions	P40646, Q9R1T6	Gene names	Sox7, Sox-7
Domain Architecture
Description	Transcription factor SOX-7 (mSOX7).

SOX4_HUMAN
θ value	0.000270298 (rank : 38)	NC score	0.509699 (rank : 43)
Query Neighborhood Hits	126	Target Neighborhood Hits	111	Shared Neighborhood Hits	77
SwissProt Accessions	Q06945	Gene names	SOX4
Domain Architecture
Description	Transcription factor SOX-4.

SOX7_HUMAN
θ value	0.000270298 (rank : 39)	NC score	0.514829 (rank : 37)
Query Neighborhood Hits	126	Target Neighborhood Hits	140	Shared Neighborhood Hits	80
SwissProt Accessions	Q9BT81	Gene names	SOX7
Domain Architecture
Description	Transcription factor SOX-7.

SOX12_HUMAN
θ value	0.00035302 (rank : 40)	NC score	0.523177 (rank : 31)
Query Neighborhood Hits	126	Target Neighborhood Hits	111	Shared Neighborhood Hits	74
SwissProt Accessions	O15370, Q9NUD4	Gene names	SOX12, SOX22
Domain Architecture
Description	SOX-12 protein (SOX-22 protein).

SOX12_MOUSE
θ value	0.00035302 (rank : 41)	NC score	0.522627 (rank : 32)
Query Neighborhood Hits	126	Target Neighborhood Hits	98	Shared Neighborhood Hits	74
SwissProt Accessions	Q04890, P70417, Q6NXL2	Gene names	Sox12, Sox-12
Domain Architecture	No domain graphic available
Description	SOX-12 protein.

SOX30_HUMAN
θ value	0.00035302 (rank : 42)	NC score	0.483031 (rank : 60)
Query Neighborhood Hits	126	Target Neighborhood Hits	305	Shared Neighborhood Hits	80
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

SOX30_MOUSE
θ value	0.00035302 (rank : 43)	NC score	0.487304 (rank : 59)
Query Neighborhood Hits	126	Target Neighborhood Hits	374	Shared Neighborhood Hits	81
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

SOX4_MOUSE
θ value	0.00035302 (rank : 44)	NC score	0.513165 (rank : 40)
Query Neighborhood Hits	126	Target Neighborhood Hits	108	Shared Neighborhood Hits	77
SwissProt Accessions	Q06831	Gene names	Sox4, Sox-4
Domain Architecture
Description	Transcription factor SOX-4.

CIC_HUMAN
θ value	0.000461057 (rank : 45)	NC score	0.413080 (rank : 70)
Query Neighborhood Hits	126	Target Neighborhood Hits	992	Shared Neighborhood Hits	82
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CIC_MOUSE
θ value	0.000461057 (rank : 46)	NC score	0.437690 (rank : 69)
Query Neighborhood Hits	126	Target Neighborhood Hits	742	Shared Neighborhood Hits	80
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

SOX15_HUMAN
θ value	0.000602161 (rank : 47)	NC score	0.531214 (rank : 26)
Query Neighborhood Hits	126	Target Neighborhood Hits	134	Shared Neighborhood Hits	80
SwissProt Accessions	O60248, P35717, Q9Y6W7	Gene names	SOX15, SOX12, SOX20, SOX26, SOX27
Domain Architecture
Description	SOX-15 protein (SOX-20 protein) (SOX-12 protein).

SOX18_MOUSE
θ value	0.000602161 (rank : 48)	NC score	0.514809 (rank : 38)
Query Neighborhood Hits	126	Target Neighborhood Hits	105	Shared Neighborhood Hits	75
SwissProt Accessions	P43680, Q9EQ73	Gene names	Sox18, Sox-18
Domain Architecture
Description	Transcription factor SOX-18.

SOX13_HUMAN
θ value	0.000786445 (rank : 49)	NC score	0.452433 (rank : 66)
Query Neighborhood Hits	126	Target Neighborhood Hits	464	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

SOX13_MOUSE
θ value	0.000786445 (rank : 50)	NC score	0.455374 (rank : 63)
Query Neighborhood Hits	126	Target Neighborhood Hits	495	Shared Neighborhood Hits	83
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

SOX14_HUMAN
θ value	0.000786445 (rank : 51)	NC score	0.520642 (rank : 35)
Query Neighborhood Hits	126	Target Neighborhood Hits	102	Shared Neighborhood Hits	80
SwissProt Accessions	O95416, Q3KPH7	Gene names	SOX14, SOX28
Domain Architecture
Description	Transcription factor SOX-14.

SOX14_MOUSE
θ value	0.000786445 (rank : 52)	NC score	0.520669 (rank : 34)
Query Neighborhood Hits	126	Target Neighborhood Hits	100	Shared Neighborhood Hits	80
SwissProt Accessions	Q04892, Q9JLC9, Q9JLD0, Q9QXU4	Gene names	Sox14, Sox-14
Domain Architecture
Description	Transcription factor SOX-14.

SOX17_MOUSE
θ value	0.000786445 (rank : 53)	NC score	0.499292 (rank : 53)
Query Neighborhood Hits	126	Target Neighborhood Hits	223	Shared Neighborhood Hits	77
SwissProt Accessions	Q61473, Q61472, Q62248	Gene names	Sox17, Sox-17
Domain Architecture
Description	Transcription factor SOX-17.

SOX6_HUMAN
θ value	0.000786445 (rank : 54)	NC score	0.456630 (rank : 61)
Query Neighborhood Hits	126	Target Neighborhood Hits	332	Shared Neighborhood Hits	87
SwissProt Accessions	P35712, Q9BXQ3, Q9BXQ4, Q9BXQ5, Q9H0I8	Gene names	SOX6
Domain Architecture
Description	Transcription factor SOX-6.

SOX6_MOUSE
θ value	0.000786445 (rank : 55)	NC score	0.455726 (rank : 62)
Query Neighborhood Hits	126	Target Neighborhood Hits	341	Shared Neighborhood Hits	86
SwissProt Accessions	P40645, Q62250, Q9QWS5	Gene names	Sox6, Sox-6
Domain Architecture
Description	Transcription factor SOX-6 (SOX-LZ).

SOX17_HUMAN
θ value	0.00134147 (rank : 56)	NC score	0.498276 (rank : 56)
Query Neighborhood Hits	126	Target Neighborhood Hits	108	Shared Neighborhood Hits	77
SwissProt Accessions	Q9H6I2	Gene names	SOX17
Domain Architecture
Description	Transcription factor SOX-17.

SRY_HUMAN
θ value	0.00134147 (rank : 57)	NC score	0.518217 (rank : 36)
Query Neighborhood Hits	126	Target Neighborhood Hits	83	Shared Neighborhood Hits	80
SwissProt Accessions	Q05066	Gene names	SRY, TDF
Domain Architecture
Description	Sex-determining region Y protein (Testis-determining factor).

HBP1_HUMAN
θ value	0.00175202 (rank : 58)	NC score	0.444937 (rank : 67)
Query Neighborhood Hits	126	Target Neighborhood Hits	89	Shared Neighborhood Hits	74
SwissProt Accessions	O60381, Q8TBM1, Q8TE93, Q96AJ2	Gene names	HBP1
Domain Architecture	No domain graphic available
Description	HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1).

HBP1_MOUSE
θ value	0.00175202 (rank : 59)	NC score	0.443905 (rank : 68)
Query Neighborhood Hits	126	Target Neighborhood Hits	86	Shared Neighborhood Hits	74
SwissProt Accessions	Q8R316, Q3V0I4, Q8BUS3, Q8C199	Gene names	Hbp1
Domain Architecture	No domain graphic available
Description	HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1).

SOX15_MOUSE
θ value	0.00175202 (rank : 60)	NC score	0.525424 (rank : 28)
Query Neighborhood Hits	126	Target Neighborhood Hits	100	Shared Neighborhood Hits	80
SwissProt Accessions	P43267, O70204, P70418, Q62246, Q91V00, Q91V43, Q920T1, Q9JLG2	Gene names	Sox15, Sox-15
Domain Architecture
Description	SOX-15 protein.

PB1_HUMAN
θ value	0.00228821 (rank : 61)	NC score	0.354049 (rank : 74)
Query Neighborhood Hits	126	Target Neighborhood Hits	261	Shared Neighborhood Hits	81
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

SOX21_HUMAN
θ value	0.00228821 (rank : 62)	NC score	0.508440 (rank : 45)
Query Neighborhood Hits	126	Target Neighborhood Hits	89	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y651, P35715, Q15504	Gene names	SOX21, SOX25, SOXA
Domain Architecture
Description	Transcription factor SOX-21 (SOX-A).

SOX21_MOUSE
θ value	0.00228821 (rank : 63)	NC score	0.508439 (rank : 46)
Query Neighborhood Hits	126	Target Neighborhood Hits	90	Shared Neighborhood Hits	79
SwissProt Accessions	Q811W0, Q8VH35	Gene names	Sox21
Domain Architecture	No domain graphic available
Description	Transcription factor SOX-21.

SOX5_HUMAN
θ value	0.00298849 (rank : 64)	NC score	0.453690 (rank : 65)
Query Neighborhood Hits	126	Target Neighborhood Hits	219	Shared Neighborhood Hits	82
SwissProt Accessions	P35711, Q86UK8, Q8J017, Q8J018, Q8J019, Q8J020, Q8N1D9, Q8N7E0, Q8TEA4	Gene names	SOX5
Domain Architecture
Description	Transcription factor SOX-5.

SOX5_MOUSE
θ value	0.00298849 (rank : 65)	NC score	0.455193 (rank : 64)
Query Neighborhood Hits	126	Target Neighborhood Hits	196	Shared Neighborhood Hits	82
SwissProt Accessions	P35710, O88184, O89018	Gene names	Sox5, Sox-5
Domain Architecture
Description	Transcription factor SOX-5.

SRY_MOUSE
θ value	0.00390308 (rank : 66)	NC score	0.503281 (rank : 52)
Query Neighborhood Hits	126	Target Neighborhood Hits	139	Shared Neighborhood Hits	84
SwissProt Accessions	Q05738	Gene names	Sry, Tdf, Tdy
Domain Architecture
Description	Sex-determining region Y protein (Testis-determining factor).

SOX11_HUMAN
θ value	0.00509761 (rank : 67)	NC score	0.506511 (rank : 50)
Query Neighborhood Hits	126	Target Neighborhood Hits	89	Shared Neighborhood Hits	79
SwissProt Accessions	P35716	Gene names	SOX11
Domain Architecture
Description	Transcription factor SOX-11.

SOX11_MOUSE
θ value	0.00509761 (rank : 68)	NC score	0.503751 (rank : 51)
Query Neighborhood Hits	126	Target Neighborhood Hits	96	Shared Neighborhood Hits	77
SwissProt Accessions	Q7M6Y2, O35178, O89036, Q04889, Q80XF0	Gene names	Sox11, Sox-11
Domain Architecture	No domain graphic available
Description	Transcription factor SOX-11.

SOX1_HUMAN
θ value	0.00509761 (rank : 69)	NC score	0.499243 (rank : 54)
Query Neighborhood Hits	126	Target Neighborhood Hits	90	Shared Neighborhood Hits	80
SwissProt Accessions	O00570	Gene names	SOX1
Domain Architecture
Description	SOX-1 protein.

SOX1_MOUSE
θ value	0.00509761 (rank : 70)	NC score	0.498572 (rank : 55)
Query Neighborhood Hits	126	Target Neighborhood Hits	90	Shared Neighborhood Hits	80
SwissProt Accessions	P53783	Gene names	Sox1, Sox-1
Domain Architecture
Description	SOX-1 protein.

SOX3_HUMAN
θ value	0.00869519 (rank : 71)	NC score	0.490829 (rank : 58)
Query Neighborhood Hits	126	Target Neighborhood Hits	109	Shared Neighborhood Hits	79
SwissProt Accessions	P41225, P35714, Q9NP49	Gene names	SOX3
Domain Architecture
Description	Transcription factor SOX-3.

SOX3_MOUSE
θ value	0.00869519 (rank : 72)	NC score	0.493572 (rank : 57)
Query Neighborhood Hits	126	Target Neighborhood Hits	101	Shared Neighborhood Hits	79
SwissProt Accessions	P53784	Gene names	Sox3, Sox-3
Domain Architecture
Description	Transcription factor SOX-3.

LEO1_MOUSE
θ value	0.0961366 (rank : 73)	NC score	0.066413 (rank : 88)
Query Neighborhood Hits	126	Target Neighborhood Hits	946	Shared Neighborhood Hits	41
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

TCF7_MOUSE
θ value	0.0961366 (rank : 74)	NC score	0.278323 (rank : 76)
Query Neighborhood Hits	126	Target Neighborhood Hits	277	Shared Neighborhood Hits	66
SwissProt Accessions	Q00417	Gene names	Tcf7, Tcf-1, Tcf1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

CAN3_MOUSE
θ value	0.163984 (rank : 75)	NC score	0.021661 (rank : 115)
Query Neighborhood Hits	126	Target Neighborhood Hits	115	Shared Neighborhood Hits	6
SwissProt Accessions	Q64691, Q9WUC5	Gene names	Capn3
Domain Architecture
Description	Calpain-3 (EC 3.4.22.-) (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3).

SMCE1_HUMAN
θ value	0.163984 (rank : 76)	NC score	0.395827 (rank : 71)
Query Neighborhood Hits	126	Target Neighborhood Hits	272	Shared Neighborhood Hits	82
SwissProt Accessions	Q969G3, O43539	Gene names	SMARCE1, BAF57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 (BRG1-associated factor 57).

SMCE1_MOUSE
θ value	0.163984 (rank : 77)	NC score	0.374114 (rank : 73)
Query Neighborhood Hits	126	Target Neighborhood Hits	409	Shared Neighborhood Hits	84
SwissProt Accessions	O54941, Q8BPD9	Gene names	Smarce1, Baf57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator chromatin subfamily E member 1 (BRG1-associated factor 57).

MY18A_MOUSE
θ value	0.279714 (rank : 78)	NC score	0.015694 (rank : 121)
Query Neighborhood Hits	126	Target Neighborhood Hits	1989	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

SEC63_HUMAN
θ value	0.279714 (rank : 79)	NC score	0.053208 (rank : 90)
Query Neighborhood Hits	126	Target Neighborhood Hits	586	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

SEC63_MOUSE
θ value	0.279714 (rank : 80)	NC score	0.049742 (rank : 92)
Query Neighborhood Hits	126	Target Neighborhood Hits	601	Shared Neighborhood Hits	22
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

AN30A_HUMAN
θ value	0.47712 (rank : 81)	NC score	0.014233 (rank : 124)
Query Neighborhood Hits	126	Target Neighborhood Hits	1119	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

NSBP1_MOUSE
θ value	0.47712 (rank : 82)	NC score	0.046882 (rank : 93)
Query Neighborhood Hits	126	Target Neighborhood Hits	681	Shared Neighborhood Hits	31
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

ENKUR_MOUSE
θ value	0.62314 (rank : 83)	NC score	0.043548 (rank : 95)
Query Neighborhood Hits	126	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	Q6SP97	Gene names
Domain Architecture	No domain graphic available
Description	Enkurin.

LEF1_HUMAN
θ value	0.813845 (rank : 84)	NC score	0.269755 (rank : 77)
Query Neighborhood Hits	126	Target Neighborhood Hits	150	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UJU2, Q9HAZ0	Gene names	LEF1
Domain Architecture
Description	Lymphoid enhancer-binding factor 1 (LEF-1) (T cell-specific transcription factor 1-alpha) (TCF1-alpha).

LEF1_MOUSE
θ value	0.813845 (rank : 85)	NC score	0.269207 (rank : 78)
Query Neighborhood Hits	126	Target Neighborhood Hits	161	Shared Neighborhood Hits	74
SwissProt Accessions	P27782	Gene names	Lef1, Lef-1
Domain Architecture
Description	Lymphoid enhancer-binding factor 1 (LEF-1).

PHF20_HUMAN
θ value	1.38821 (rank : 86)	NC score	0.040234 (rank : 96)
Query Neighborhood Hits	126	Target Neighborhood Hits	394	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

SMRC1_MOUSE
θ value	1.38821 (rank : 87)	NC score	0.031842 (rank : 104)
Query Neighborhood Hits	126	Target Neighborhood Hits	459	Shared Neighborhood Hits	32
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

TCF7_HUMAN
θ value	1.38821 (rank : 88)	NC score	0.292221 (rank : 75)
Query Neighborhood Hits	126	Target Neighborhood Hits	186	Shared Neighborhood Hits	69
SwissProt Accessions	P36402, Q9UKI4	Gene names	TCF7, TCF1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

TGON2_HUMAN
θ value	1.38821 (rank : 89)	NC score	0.029294 (rank : 107)
Query Neighborhood Hits	126	Target Neighborhood Hits	1037	Shared Neighborhood Hits	30
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

CF010_HUMAN
θ value	1.81305 (rank : 90)	NC score	0.039355 (rank : 97)
Query Neighborhood Hits	126	Target Neighborhood Hits	329	Shared Neighborhood Hits	17
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

MDN1_HUMAN
θ value	1.81305 (rank : 91)	NC score	0.036653 (rank : 101)
Query Neighborhood Hits	126	Target Neighborhood Hits	662	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

CCD46_HUMAN
θ value	2.36792 (rank : 92)	NC score	0.014427 (rank : 123)
Query Neighborhood Hits	126	Target Neighborhood Hits	1430	Shared Neighborhood Hits	32
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

IMB3_HUMAN
θ value	2.36792 (rank : 93)	NC score	0.024503 (rank : 111)
Query Neighborhood Hits	126	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	O00410, O15257	Gene names	RANBP5, KPNB3
Domain Architecture
Description	Importin beta-3 (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5).

IMB3_MOUSE
θ value	2.36792 (rank : 94)	NC score	0.024510 (rank : 110)
Query Neighborhood Hits	126	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BKC5, Q3TEG2, Q7TQC6, Q9EQ30	Gene names	Ranbp5, Kpnb3
Domain Architecture
Description	Importin beta-3 (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5).

PHF20_MOUSE
θ value	2.36792 (rank : 95)	NC score	0.035628 (rank : 102)
Query Neighborhood Hits	126	Target Neighborhood Hits	513	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

PLCB3_MOUSE
θ value	2.36792 (rank : 96)	NC score	0.016253 (rank : 120)
Query Neighborhood Hits	126	Target Neighborhood Hits	344	Shared Neighborhood Hits	10
SwissProt Accessions	P51432	Gene names	Plcb3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

LEO1_HUMAN
θ value	3.0926 (rank : 97)	NC score	0.046160 (rank : 94)
Query Neighborhood Hits	126	Target Neighborhood Hits	958	Shared Neighborhood Hits	38
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

MATR3_MOUSE
θ value	3.0926 (rank : 98)	NC score	0.037843 (rank : 100)
Query Neighborhood Hits	126	Target Neighborhood Hits	321	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

MLL3_HUMAN
θ value	3.0926 (rank : 99)	NC score	0.027465 (rank : 109)
Query Neighborhood Hits	126	Target Neighborhood Hits	1644	Shared Neighborhood Hits	34
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

RBBP6_MOUSE
θ value	3.0926 (rank : 100)	NC score	0.027704 (rank : 108)
Query Neighborhood Hits	126	Target Neighborhood Hits	1014	Shared Neighborhood Hits	35
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

CEBPZ_MOUSE
θ value	4.03905 (rank : 101)	NC score	0.023355 (rank : 114)
Query Neighborhood Hits	126	Target Neighborhood Hits	60	Shared Neighborhood Hits	7
SwissProt Accessions	P53569, Q3TXW5, Q3TYA8, Q3UWQ7	Gene names	Cebpz, Cbf2, Cebpa-rs1
Domain Architecture
Description	CCAAT/enhancer-binding protein zeta (CCAAT-box-binding transcription factor) (CCAAT-binding factor) (CBF).

MY18A_HUMAN
θ value	4.03905 (rank : 102)	NC score	0.010803 (rank : 127)
Query Neighborhood Hits	126	Target Neighborhood Hits	1929	Shared Neighborhood Hits	32
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

NPBL_MOUSE
θ value	4.03905 (rank : 103)	NC score	0.030987 (rank : 106)
Query Neighborhood Hits	126	Target Neighborhood Hits	1041	Shared Neighborhood Hits	44
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

NUFP1_HUMAN
θ value	4.03905 (rank : 104)	NC score	0.019222 (rank : 116)
Query Neighborhood Hits	126	Target Neighborhood Hits	193	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UHK0, Q8WVM5, Q96SG1	Gene names	NUFIP1
Domain Architecture	No domain graphic available
Description	Nuclear fragile X mental retardation-interacting protein 1 (Nuclear FMRP-interacting protein 1).

OSBL8_HUMAN
θ value	4.03905 (rank : 105)	NC score	0.017826 (rank : 119)
Query Neighborhood Hits	126	Target Neighborhood Hits	289	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

PSMD2_MOUSE
θ value	4.03905 (rank : 106)	NC score	0.011763 (rank : 125)
Query Neighborhood Hits	126	Target Neighborhood Hits	147	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VDM4	Gene names	Psmd2
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97).

CD2L5_HUMAN
θ value	5.27518 (rank : 107)	NC score	-0.003339 (rank : 132)
Query Neighborhood Hits	126	Target Neighborhood Hits	987	Shared Neighborhood Hits	11
SwissProt Accessions	Q14004, Q6DKQ9, Q75MH4, Q75MH5, Q96JN4, Q9H4A0, Q9H4A1, Q9UDR4	Gene names	CDC2L5, CDC2L, CHED, KIAA1791
Domain Architecture
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5) (Cholinesterase-related cell division controller).

DNMT1_HUMAN
θ value	5.27518 (rank : 108)	NC score	0.030990 (rank : 105)
Query Neighborhood Hits	126	Target Neighborhood Hits	401	Shared Neighborhood Hits	28
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

IF2B_HUMAN
θ value	5.27518 (rank : 109)	NC score	0.018819 (rank : 117)
Query Neighborhood Hits	126	Target Neighborhood Hits	60	Shared Neighborhood Hits	6
SwissProt Accessions	P20042, Q9BVU0, Q9UJE4	Gene names	EIF2S2, EIF2B
Domain Architecture
Description	Eukaryotic translation initiation factor 2 subunit 2 (Eukaryotic translation initiation factor 2 subunit beta) (eIF-2-beta).

MATR3_HUMAN
θ value	5.27518 (rank : 110)	NC score	0.038866 (rank : 99)
Query Neighborhood Hits	126	Target Neighborhood Hits	325	Shared Neighborhood Hits	19
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

TF7L1_HUMAN
θ value	5.27518 (rank : 111)	NC score	0.238822 (rank : 81)
Query Neighborhood Hits	126	Target Neighborhood Hits	129	Shared Neighborhood Hits	67
SwissProt Accessions	Q9HCS4, Q53R97, Q6PD70, Q9NP00	Gene names	TCF7L1, TCF3
Domain Architecture
Description	Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF- 3).

TF7L1_MOUSE
θ value	5.27518 (rank : 112)	NC score	0.238534 (rank : 82)
Query Neighborhood Hits	126	Target Neighborhood Hits	131	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Z1J1, O70450, O70573	Gene names	Tcf7l1, Tcf3
Domain Architecture
Description	Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF-3) (mTCF-3).

VPS72_HUMAN
θ value	5.27518 (rank : 113)	NC score	0.024306 (rank : 112)
Query Neighborhood Hits	126	Target Neighborhood Hits	274	Shared Neighborhood Hits	14
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

VPS72_MOUSE
θ value	5.27518 (rank : 114)	NC score	0.024203 (rank : 113)
Query Neighborhood Hits	126	Target Neighborhood Hits	286	Shared Neighborhood Hits	14
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

CK5P2_HUMAN
θ value	6.88961 (rank : 115)	NC score	0.006752 (rank : 129)
Query Neighborhood Hits	126	Target Neighborhood Hits	1433	Shared Neighborhood Hits	25
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

GAS7_MOUSE
θ value	6.88961 (rank : 116)	NC score	0.018315 (rank : 118)
Query Neighborhood Hits	126	Target Neighborhood Hits	259	Shared Neighborhood Hits	11
SwissProt Accessions	Q60780, Q9QY25, Q9QY26, Q9QY34	Gene names	Gas7
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

TXND2_MOUSE
θ value	6.88961 (rank : 117)	NC score	0.032503 (rank : 103)
Query Neighborhood Hits	126	Target Neighborhood Hits	828	Shared Neighborhood Hits	32
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

ZBT10_HUMAN
θ value	6.88961 (rank : 118)	NC score	-0.003855 (rank : 133)
Query Neighborhood Hits	126	Target Neighborhood Hits	831	Shared Neighborhood Hits	5
SwissProt Accessions	Q96DT7, Q86W96, Q8IXI9, Q96MH9	Gene names	ZBTB10, RINZF, RINZFC
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 10 (Zinc finger protein RIN ZF).

BPTF_HUMAN
θ value	8.99809 (rank : 119)	NC score	0.014446 (rank : 122)
Query Neighborhood Hits	126	Target Neighborhood Hits	786	Shared Neighborhood Hits	29
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

CD2L5_MOUSE
θ value	8.99809 (rank : 120)	NC score	-0.003993 (rank : 134)
Query Neighborhood Hits	126	Target Neighborhood Hits	1011	Shared Neighborhood Hits	12
SwissProt Accessions	Q69ZA1, Q80V11, Q8BZG1, Q8K0A4	Gene names	Cdc2l5, Kiaa1791
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5).

ERIC1_HUMAN
θ value	8.99809 (rank : 121)	NC score	0.039144 (rank : 98)
Query Neighborhood Hits	126	Target Neighborhood Hits	364	Shared Neighborhood Hits	20
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

FLIP1_MOUSE
θ value	8.99809 (rank : 122)	NC score	0.005461 (rank : 131)
Query Neighborhood Hits	126	Target Neighborhood Hits	1176	Shared Neighborhood Hits	16
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

GAS7_HUMAN
θ value	8.99809 (rank : 123)	NC score	0.011397 (rank : 126)
Query Neighborhood Hits	126	Target Neighborhood Hits	258	Shared Neighborhood Hits	10
SwissProt Accessions	O60861, O43144	Gene names	GAS7, KIAA0394
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

RM46_HUMAN
θ value	8.99809 (rank : 124)	NC score	0.008815 (rank : 128)
Query Neighborhood Hits	126	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H2W6, Q9HBU8	Gene names	MRPL46, C15orf4, LIECG2
Domain Architecture	No domain graphic available
Description	39S ribosomal protein L46, mitochondrial precursor (L46mt) (MRP-L46) (P2ECSL).

SEC62_MOUSE
θ value	8.99809 (rank : 125)	NC score	0.067691 (rank : 87)
Query Neighborhood Hits	126	Target Neighborhood Hits	101	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BU14, Q6NX81	Gene names	Tloc1, Sec62
Domain Architecture	No domain graphic available
Description	Translocation protein SEC62 (Translocation protein 1) (TP-1).

SMC2_MOUSE
θ value	8.99809 (rank : 126)	NC score	0.006425 (rank : 130)
Query Neighborhood Hits	126	Target Neighborhood Hits	1131	Shared Neighborhood Hits	21
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

IPR1_MOUSE
θ value	θ > 10 (rank : 127)	NC score	0.068026 (rank : 86)
Query Neighborhood Hits	126	Target Neighborhood Hits	65	Shared Neighborhood Hits	1
SwissProt Accessions	Q8BVK9, Q3UCV7, Q80V00	Gene names	Ipr1, Ifi75
Domain Architecture	No domain graphic available
Description	Intracellular pathogen resistance protein 1.

LY10_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.085570 (rank : 85)
Query Neighborhood Hits	126	Target Neighborhood Hits	151	Shared Neighborhood Hits	6
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

S100R_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.092506 (rank : 84)
Query Neighborhood Hits	126	Target Neighborhood Hits	11	Shared Neighborhood Hits	1
SwissProt Accessions	Q99388	Gene names	D1Lub1, Sp100-rs
Domain Architecture
Description	Putative Sp100-related protein.

SEC62_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.051243 (rank : 91)
Query Neighborhood Hits	126	Target Neighborhood Hits	100	Shared Neighborhood Hits	19
SwissProt Accessions	Q99442, O00682, O00729	Gene names	TLOC1, SEC62
Domain Architecture	No domain graphic available
Description	Translocation protein SEC62 (Translocation protein 1) (TP-1) (hTP-1).

SP100_MOUSE
θ value	θ > 10 (rank : 131)	NC score	0.100075 (rank : 83)
Query Neighborhood Hits	126	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	O35892, O35897, O88392, O88395	Gene names	Sp100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein).

SP110_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.060286 (rank : 89)
Query Neighborhood Hits	126	Target Neighborhood Hits	141	Shared Neighborhood Hits	7
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

TF7L2_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.242192 (rank : 80)
Query Neighborhood Hits	126	Target Neighborhood Hits	119	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NQB0, O00185, Q9NQB1, Q9NQB2, Q9NQB3, Q9NQB4, Q9NQB5, Q9NQB6, Q9NQB7, Q9ULC2	Gene names	TCF7L2, TCF4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (hTCF-4).

TF7L2_MOUSE
θ value	θ > 10 (rank : 134)	NC score	0.243634 (rank : 79)
Query Neighborhood Hits	126	Target Neighborhood Hits	95	Shared Neighborhood Hits	67
SwissProt Accessions	Q924A0, O70574, Q91XP2, Q91XP3, Q91XP4, Q924A1, Q9Z0V3, Q9Z0V4	Gene names	Tcf7l2, Tcf4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (mTCF-4).

Hits sorted by NC score

HMGB1_HUMAN
NC score	0.999962 (rank : 1)	θ value	8.77142e-88 (rank : 1)
Query Neighborhood Hits	126	Target Neighborhood Hits	126	Shared Neighborhood Hits	126
SwissProt Accessions	P09429, Q6IBE1	Gene names	HMGB1, HMG1
Domain Architecture
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

HMGB1_MOUSE
NC score	0.999109 (rank : 2)	θ value	8.77142e-88 (rank : 2)
Query Neighborhood Hits	126	Target Neighborhood Hits	123	Shared Neighborhood Hits	117
SwissProt Accessions	P63158, P07155, P27109, P27428	Gene names	Hmgb1, Hmg-1, Hmg1
Domain Architecture	No domain graphic available
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

HMG1X_HUMAN
NC score	0.992942 (rank : 3)	θ value	6.08852e-81 (rank : 4)
Query Neighborhood Hits	126	Target Neighborhood Hits	97	Shared Neighborhood Hits	95
SwissProt Accessions	Q9UGV6	Gene names	HMG1L10
Domain Architecture
Description	High mobility group protein 1-like 10 (HMG-1L10).

HMGB2_MOUSE
NC score	0.987914 (rank : 4)	θ value	1.77149e-80 (rank : 5)
Query Neighborhood Hits	126	Target Neighborhood Hits	111	Shared Neighborhood Hits	87
SwissProt Accessions	P30681, Q3UXT1, Q9EQD5	Gene names	Hmgb2, Hmg2
Domain Architecture
Description	High mobility group protein B2 (High mobility group protein 2) (HMG- 2).

HMGB2_HUMAN
NC score	0.987107 (rank : 5)	θ value	9.39325e-82 (rank : 3)
Query Neighborhood Hits	126	Target Neighborhood Hits	114	Shared Neighborhood Hits	87
SwissProt Accessions	P26583	Gene names	HMGB2, HMG2
Domain Architecture
Description	High mobility group protein B2 (High mobility group protein 2) (HMG- 2).

HMGB3_MOUSE
NC score	0.976476 (rank : 6)	θ value	2.74572e-65 (rank : 6)
Query Neighborhood Hits	126	Target Neighborhood Hits	88	Shared Neighborhood Hits	77
SwissProt Accessions	O54879	Gene names	Hmgb3, Hmg2a, Hmg4
Domain Architecture
Description	High mobility group protein B3 (High mobility group protein 4) (HMG-4) (High mobility group protein 2a) (HMG-2a).

HMGB3_HUMAN
NC score	0.974826 (rank : 7)	θ value	1.04338e-64 (rank : 7)
Query Neighborhood Hits	126	Target Neighborhood Hits	86	Shared Neighborhood Hits	76
SwissProt Accessions	O15347, O95556, Q6NS40	Gene names	HMGB3, HMG2A, HMG4
Domain Architecture
Description	High mobility group protein B3 (High mobility group protein 4) (HMG-4) (High mobility group protein 2a) (HMG-2a).

SP100_HUMAN
NC score	0.800974 (rank : 8)	θ value	1.84173e-61 (rank : 8)
Query Neighborhood Hits	126	Target Neighborhood Hits	117	Shared Neighborhood Hits	69
SwissProt Accessions	P23497, O75450, Q13343, Q96F70, Q96T24, Q96T95, Q9NP33, Q9UE32	Gene names	SP100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein) (Lysp100b).

SSRP1_HUMAN
NC score	0.735730 (rank : 9)	θ value	2.60593e-15 (rank : 9)
Query Neighborhood Hits	126	Target Neighborhood Hits	187	Shared Neighborhood Hits	87
SwissProt Accessions	Q08945, Q5BJG8	Gene names	SSRP1, FACT80
Domain Architecture
Description	FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (FACT 80 kDa subunit) (FACTp80) (Chromatin- specific transcription elongation factor 80 kDa subunit) (Structure- specific recognition protein 1) (hSSRP1) (Recombination signal sequence recognition protein 1) (T160).

SSRP1_MOUSE
NC score	0.726542 (rank : 10)	θ value	3.76295e-14 (rank : 10)
Query Neighborhood Hits	126	Target Neighborhood Hits	193	Shared Neighborhood Hits	91
SwissProt Accessions	Q08943, Q3U9Z2, Q3UJ75, Q4V9U4, Q8CGA6	Gene names	Ssrp1
Domain Architecture
Description	FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (Structure-specific recognition protein 1) (Recombination signal sequence recognition protein 1) (T160).

HM20B_MOUSE
NC score	0.685974 (rank : 11)	θ value	1.25267e-09 (rank : 13)
Query Neighborhood Hits	126	Target Neighborhood Hits	122	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Z104, Q9NSF7, Q9NSF8	Gene names	Hmg20b, Braf35, Hmgx2, Smarce1r
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (HMG domain protein HMG20B) (Structural DNA-binding protein BRAF35) (BRCA2- associated factor 35).

HM20B_HUMAN
NC score	0.671960 (rank : 12)	θ value	5.26297e-08 (rank : 19)
Query Neighborhood Hits	126	Target Neighborhood Hits	126	Shared Neighborhood Hits	79
SwissProt Accessions	Q9P0W2, Q6IBP8, Q8NBD5, Q9HD21, Q9Y491, Q9Y4A2	Gene names	HMG20B, BRAF35, HMGX2, SMARCE1R
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (HMG domain protein HMG20B) (Structural DNA-binding protein BRAF35) (BRCA2- associated factor 35) (Sox-like transcriptional factor).

HM2L1_HUMAN
NC score	0.654562 (rank : 13)	θ value	1.53129e-07 (rank : 21)
Query Neighborhood Hits	126	Target Neighborhood Hits	130	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UGU5, O75672, O75673, Q9UMT5	Gene names	HMG2L1, HMGBCG
Domain Architecture
Description	High mobility group protein 2-like 1 (Protein HMGBCG).

TFAM_MOUSE
NC score	0.625013 (rank : 14)	θ value	7.59969e-07 (rank : 23)
Query Neighborhood Hits	126	Target Neighborhood Hits	93	Shared Neighborhood Hits	76
SwissProt Accessions	P40630, P97894, P97906, Q543I8, Q9DBM9	Gene names	Tfam, Hmgts
Domain Architecture
Description	Transcription factor A, mitochondrial precursor (mtTFA) (Testis- specific high mobility group protein) (TS-HMG).

HM20A_HUMAN
NC score	0.603894 (rank : 15)	θ value	2.13673e-09 (rank : 14)
Query Neighborhood Hits	126	Target Neighborhood Hits	343	Shared Neighborhood Hits	79
SwissProt Accessions	Q9NP66, Q53G31, Q9NSF6	Gene names	HMG20A, HMGX1
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein HMGX1).

HM20A_MOUSE
NC score	0.602260 (rank : 16)	θ value	2.13673e-09 (rank : 15)
Query Neighborhood Hits	126	Target Neighborhood Hits	348	Shared Neighborhood Hits	79
SwissProt Accessions	Q9DC33, Q3LSF9, Q6NV87, Q8BSK1, Q8C3C1, Q8CAA0, Q9CYG2	Gene names	Hmg20a, Ibraf
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (iBRAF) (Inhibitor of BRAF35) (HMG domain protein HMGX1).

TFAM_HUMAN
NC score	0.596352 (rank : 17)	θ value	4.0297e-08 (rank : 17)
Query Neighborhood Hits	126	Target Neighborhood Hits	156	Shared Neighborhood Hits	67
SwissProt Accessions	Q00059	Gene names	TFAM, TCF6L2
Domain Architecture
Description	Transcription factor A, mitochondrial precursor (mtTFA) (Mitochondrial transcription factor 1) (MtTF1) (Transcription factor 6-like 2).

TOX_MOUSE
NC score	0.573673 (rank : 18)	θ value	7.34386e-10 (rank : 11)
Query Neighborhood Hits	126	Target Neighborhood Hits	95	Shared Neighborhood Hits	55
SwissProt Accessions	Q66JW3, Q8BKH9, Q8BYQ5, Q8R4H0	Gene names	Tox
Domain Architecture	No domain graphic available
Description	Thymus high mobility group box protein TOX.

TOX_HUMAN
NC score	0.569325 (rank : 19)	θ value	9.59137e-10 (rank : 12)
Query Neighborhood Hits	126	Target Neighborhood Hits	106	Shared Neighborhood Hits	55
SwissProt Accessions	O94900, Q96AV5	Gene names	TOX, KIAA0808
Domain Architecture	No domain graphic available
Description	Thymus high mobility group box protein TOX.

CN092_HUMAN
NC score	0.568900 (rank : 20)	θ value	6.87365e-08 (rank : 20)
Query Neighborhood Hits	126	Target Neighborhood Hits	143	Shared Neighborhood Hits	65
SwissProt Accessions	O94842	Gene names	C14orf92, KIAA0737
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

CN092_MOUSE
NC score	0.558740 (rank : 21)	θ value	5.26297e-08 (rank : 18)
Query Neighborhood Hits	126	Target Neighborhood Hits	206	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BU11, Q80UI2, Q99PN9, Q9CS16	Gene names
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

UBF1_HUMAN
NC score	0.542097 (rank : 22)	θ value	5.81887e-07 (rank : 22)
Query Neighborhood Hits	126	Target Neighborhood Hits	415	Shared Neighborhood Hits	102
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

SOX8_HUMAN
NC score	0.532764 (rank : 23)	θ value	1.09739e-05 (rank : 28)
Query Neighborhood Hits	126	Target Neighborhood Hits	100	Shared Neighborhood Hits	75
SwissProt Accessions	P57073, Q9NZW2	Gene names	SOX8
Domain Architecture
Description	Transcription factor SOX-8.

SOX8_MOUSE
NC score	0.532366 (rank : 24)	θ value	1.09739e-05 (rank : 29)
Query Neighborhood Hits	126	Target Neighborhood Hits	96	Shared Neighborhood Hits	75
SwissProt Accessions	Q04886	Gene names	Sox8, Sox-8
Domain Architecture
Description	Transcription factor SOX-8.

UBF1_MOUSE
NC score	0.531558 (rank : 25)	θ value	7.59969e-07 (rank : 24)
Query Neighborhood Hits	126	Target Neighborhood Hits	419	Shared Neighborhood Hits	100
SwissProt Accessions	P25976	Gene names	Ubtf, Tcfubf, Ubf-1, Ubf1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1).

SOX15_HUMAN
NC score	0.531214 (rank : 26)	θ value	0.000602161 (rank : 47)
Query Neighborhood Hits	126	Target Neighborhood Hits	134	Shared Neighborhood Hits	80
SwissProt Accessions	O60248, P35717, Q9Y6W7	Gene names	SOX15, SOX12, SOX20, SOX26, SOX27
Domain Architecture
Description	SOX-15 protein (SOX-20 protein) (SOX-12 protein).

SOX18_HUMAN
NC score	0.529170 (rank : 27)	θ value	4.1701e-05 (rank : 34)
Query Neighborhood Hits	126	Target Neighborhood Hits	106	Shared Neighborhood Hits	75
SwissProt Accessions	P35713, Q9NPH8	Gene names	SOX18
Domain Architecture
Description	Transcription factor SOX-18.

SOX15_MOUSE
NC score	0.525424 (rank : 28)	θ value	0.00175202 (rank : 60)
Query Neighborhood Hits	126	Target Neighborhood Hits	100	Shared Neighborhood Hits	80
SwissProt Accessions	P43267, O70204, P70418, Q62246, Q91V00, Q91V43, Q920T1, Q9JLG2	Gene names	Sox15, Sox-15
Domain Architecture
Description	SOX-15 protein.

SOX2_MOUSE
NC score	0.523533 (rank : 29)	θ value	7.1131e-05 (rank : 36)
Query Neighborhood Hits	126	Target Neighborhood Hits	90	Shared Neighborhood Hits	80
SwissProt Accessions	P48432	Gene names	Sox2, Sox-2
Domain Architecture
Description	Transcription factor SOX-2.

SOX2_HUMAN
NC score	0.523460 (rank : 30)	θ value	7.1131e-05 (rank : 35)
Query Neighborhood Hits	126	Target Neighborhood Hits	89	Shared Neighborhood Hits	80
SwissProt Accessions	P48431, Q14537	Gene names	SOX2
Domain Architecture
Description	Transcription factor SOX-2.

SOX12_HUMAN
NC score	0.523177 (rank : 31)	θ value	0.00035302 (rank : 40)
Query Neighborhood Hits	126	Target Neighborhood Hits	111	Shared Neighborhood Hits	74
SwissProt Accessions	O15370, Q9NUD4	Gene names	SOX12, SOX22
Domain Architecture
Description	SOX-12 protein (SOX-22 protein).

SOX12_MOUSE
NC score	0.522627 (rank : 32)	θ value	0.00035302 (rank : 41)
Query Neighborhood Hits	126	Target Neighborhood Hits	98	Shared Neighborhood Hits	74
SwissProt Accessions	Q04890, P70417, Q6NXL2	Gene names	Sox12, Sox-12
Domain Architecture	No domain graphic available
Description	SOX-12 protein.

SOX7_MOUSE
NC score	0.521934 (rank : 33)	θ value	0.000158464 (rank : 37)
Query Neighborhood Hits	126	Target Neighborhood Hits	105	Shared Neighborhood Hits	79
SwissProt Accessions	P40646, Q9R1T6	Gene names	Sox7, Sox-7
Domain Architecture
Description	Transcription factor SOX-7 (mSOX7).

SOX14_MOUSE
NC score	0.520669 (rank : 34)	θ value	0.000786445 (rank : 52)
Query Neighborhood Hits	126	Target Neighborhood Hits	100	Shared Neighborhood Hits	80
SwissProt Accessions	Q04892, Q9JLC9, Q9JLD0, Q9QXU4	Gene names	Sox14, Sox-14
Domain Architecture
Description	Transcription factor SOX-14.

SOX14_HUMAN
NC score	0.520642 (rank : 35)	θ value	0.000786445 (rank : 51)
Query Neighborhood Hits	126	Target Neighborhood Hits	102	Shared Neighborhood Hits	80
SwissProt Accessions	O95416, Q3KPH7	Gene names	SOX14, SOX28
Domain Architecture
Description	Transcription factor SOX-14.

SRY_HUMAN
NC score	0.518217 (rank : 36)	θ value	0.00134147 (rank : 57)
Query Neighborhood Hits	126	Target Neighborhood Hits	83	Shared Neighborhood Hits	80
SwissProt Accessions	Q05066	Gene names	SRY, TDF
Domain Architecture
Description	Sex-determining region Y protein (Testis-determining factor).

SOX7_HUMAN
NC score	0.514829 (rank : 37)	θ value	0.000270298 (rank : 39)
Query Neighborhood Hits	126	Target Neighborhood Hits	140	Shared Neighborhood Hits	80
SwissProt Accessions	Q9BT81	Gene names	SOX7
Domain Architecture
Description	Transcription factor SOX-7.

SOX18_MOUSE
NC score	0.514809 (rank : 38)	θ value	0.000602161 (rank : 48)
Query Neighborhood Hits	126	Target Neighborhood Hits	105	Shared Neighborhood Hits	75
SwissProt Accessions	P43680, Q9EQ73	Gene names	Sox18, Sox-18
Domain Architecture
Description	Transcription factor SOX-18.

SOX9_MOUSE
NC score	0.514405 (rank : 39)	θ value	1.43324e-05 (rank : 31)
Query Neighborhood Hits	126	Target Neighborhood Hits	188	Shared Neighborhood Hits	76
SwissProt Accessions	Q04887, Q8C7L2, Q91ZK2, Q99KQ0	Gene names	Sox9, Sox-9
Domain Architecture
Description	Transcription factor SOX-9.

SOX4_MOUSE
NC score	0.513165 (rank : 40)	θ value	0.00035302 (rank : 44)
Query Neighborhood Hits	126	Target Neighborhood Hits	108	Shared Neighborhood Hits	77
SwissProt Accessions	Q06831	Gene names	Sox4, Sox-4
Domain Architecture
Description	Transcription factor SOX-4.

SOX9_HUMAN
NC score	0.513132 (rank : 41)	θ value	1.43324e-05 (rank : 30)
Query Neighborhood Hits	126	Target Neighborhood Hits	210	Shared Neighborhood Hits	76
SwissProt Accessions	P48436	Gene names	SOX9
Domain Architecture
Description	Transcription factor SOX-9.

GCX1_HUMAN
NC score	0.509847 (rank : 42)	θ value	1.38499e-08 (rank : 16)
Query Neighborhood Hits	126	Target Neighborhood Hits	132	Shared Neighborhood Hits	55
SwissProt Accessions	Q96NM4, Q5TE33, Q5TE34, Q5TE35, Q96IC9, Q9BQN5	Gene names	GCX1, C20orf100
Domain Architecture
Description	Granulosa cell HMG box protein 1 (GCX-1).

SOX4_HUMAN
NC score	0.509699 (rank : 43)	θ value	0.000270298 (rank : 38)
Query Neighborhood Hits	126	Target Neighborhood Hits	111	Shared Neighborhood Hits	77
SwissProt Accessions	Q06945	Gene names	SOX4
Domain Architecture
Description	Transcription factor SOX-4.

BBX_MOUSE
NC score	0.509577 (rank : 44)	θ value	4.1701e-05 (rank : 33)
Query Neighborhood Hits	126	Target Neighborhood Hits	152	Shared Neighborhood Hits	79
SwissProt Accessions	Q8VBW5, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VI48, Q8VI49, Q8VI50, Q9CS94	Gene names	Bbx, Hbp2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

SOX21_HUMAN
NC score	0.508440 (rank : 45)	θ value	0.00228821 (rank : 62)
Query Neighborhood Hits	126	Target Neighborhood Hits	89	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y651, P35715, Q15504	Gene names	SOX21, SOX25, SOXA
Domain Architecture
Description	Transcription factor SOX-21 (SOX-A).

SOX21_MOUSE
NC score	0.508439 (rank : 46)	θ value	0.00228821 (rank : 63)
Query Neighborhood Hits	126	Target Neighborhood Hits	90	Shared Neighborhood Hits	79
SwissProt Accessions	Q811W0, Q8VH35	Gene names	Sox21
Domain Architecture	No domain graphic available
Description	Transcription factor SOX-21.

BBX_HUMAN
NC score	0.508246 (rank : 47)	θ value	1.87187e-05 (rank : 32)
Query Neighborhood Hits	126	Target Neighborhood Hits	167	Shared Neighborhood Hits	78
SwissProt Accessions	Q8WY36, Q2TAJ1, Q7L3J8, Q7LBY8, Q8NDB0, Q8WY35, Q9H0J6	Gene names	BBX, HBP2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

SOX10_MOUSE
NC score	0.508133 (rank : 48)	θ value	6.43352e-06 (rank : 27)
Query Neighborhood Hits	126	Target Neighborhood Hits	110	Shared Neighborhood Hits	71
SwissProt Accessions	Q04888, O08518, O09141, O54856, P70416	Gene names	Sox10, Sox-10, Sox21
Domain Architecture
Description	Transcription factor SOX-10 (SOX-21) (Transcription factor SOX-M).

SOX10_HUMAN
NC score	0.507600 (rank : 49)	θ value	6.43352e-06 (rank : 26)
Query Neighborhood Hits	126	Target Neighborhood Hits	122	Shared Neighborhood Hits	71
SwissProt Accessions	P56693	Gene names	SOX10
Domain Architecture
Description	Transcription factor SOX-10.

SOX11_HUMAN
NC score	0.506511 (rank : 50)	θ value	0.00509761 (rank : 67)
Query Neighborhood Hits	126	Target Neighborhood Hits	89	Shared Neighborhood Hits	79
SwissProt Accessions	P35716	Gene names	SOX11
Domain Architecture
Description	Transcription factor SOX-11.

SOX11_MOUSE
NC score	0.503751 (rank : 51)	θ value	0.00509761 (rank : 68)
Query Neighborhood Hits	126	Target Neighborhood Hits	96	Shared Neighborhood Hits	77
SwissProt Accessions	Q7M6Y2, O35178, O89036, Q04889, Q80XF0	Gene names	Sox11, Sox-11
Domain Architecture	No domain graphic available
Description	Transcription factor SOX-11.

SRY_MOUSE
NC score	0.503281 (rank : 52)	θ value	0.00390308 (rank : 66)
Query Neighborhood Hits	126	Target Neighborhood Hits	139	Shared Neighborhood Hits	84
SwissProt Accessions	Q05738	Gene names	Sry, Tdf, Tdy
Domain Architecture
Description	Sex-determining region Y protein (Testis-determining factor).

SOX17_MOUSE
NC score	0.499292 (rank : 53)	θ value	0.000786445 (rank : 53)
Query Neighborhood Hits	126	Target Neighborhood Hits	223	Shared Neighborhood Hits	77
SwissProt Accessions	Q61473, Q61472, Q62248	Gene names	Sox17, Sox-17
Domain Architecture
Description	Transcription factor SOX-17.

SOX1_HUMAN
NC score	0.499243 (rank : 54)	θ value	0.00509761 (rank : 69)
Query Neighborhood Hits	126	Target Neighborhood Hits	90	Shared Neighborhood Hits	80
SwissProt Accessions	O00570	Gene names	SOX1
Domain Architecture
Description	SOX-1 protein.

SOX1_MOUSE
NC score	0.498572 (rank : 55)	θ value	0.00509761 (rank : 70)
Query Neighborhood Hits	126	Target Neighborhood Hits	90	Shared Neighborhood Hits	80
SwissProt Accessions	P53783	Gene names	Sox1, Sox-1
Domain Architecture
Description	SOX-1 protein.

SOX17_HUMAN
NC score	0.498276 (rank : 56)	θ value	0.00134147 (rank : 56)
Query Neighborhood Hits	126	Target Neighborhood Hits	108	Shared Neighborhood Hits	77
SwissProt Accessions	Q9H6I2	Gene names	SOX17
Domain Architecture
Description	Transcription factor SOX-17.

SOX3_MOUSE
NC score	0.493572 (rank : 57)	θ value	0.00869519 (rank : 72)
Query Neighborhood Hits	126	Target Neighborhood Hits	101	Shared Neighborhood Hits	79
SwissProt Accessions	P53784	Gene names	Sox3, Sox-3
Domain Architecture
Description	Transcription factor SOX-3.

SOX3_HUMAN
NC score	0.490829 (rank : 58)	θ value	0.00869519 (rank : 71)
Query Neighborhood Hits	126	Target Neighborhood Hits	109	Shared Neighborhood Hits	79
SwissProt Accessions	P41225, P35714, Q9NP49	Gene names	SOX3
Domain Architecture
Description	Transcription factor SOX-3.

SOX30_MOUSE
NC score	0.487304 (rank : 59)	θ value	0.00035302 (rank : 43)
Query Neighborhood Hits	126	Target Neighborhood Hits	374	Shared Neighborhood Hits	81
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

SOX30_HUMAN
NC score	0.483031 (rank : 60)	θ value	0.00035302 (rank : 42)
Query Neighborhood Hits	126	Target Neighborhood Hits	305	Shared Neighborhood Hits	80
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

SOX6_HUMAN
NC score	0.456630 (rank : 61)	θ value	0.000786445 (rank : 54)
Query Neighborhood Hits	126	Target Neighborhood Hits	332	Shared Neighborhood Hits	87
SwissProt Accessions	P35712, Q9BXQ3, Q9BXQ4, Q9BXQ5, Q9H0I8	Gene names	SOX6
Domain Architecture
Description	Transcription factor SOX-6.

SOX6_MOUSE
NC score	0.455726 (rank : 62)	θ value	0.000786445 (rank : 55)
Query Neighborhood Hits	126	Target Neighborhood Hits	341	Shared Neighborhood Hits	86
SwissProt Accessions	P40645, Q62250, Q9QWS5	Gene names	Sox6, Sox-6
Domain Architecture
Description	Transcription factor SOX-6 (SOX-LZ).

SOX13_MOUSE
NC score	0.455374 (rank : 63)	θ value	0.000786445 (rank : 50)
Query Neighborhood Hits	126	Target Neighborhood Hits	495	Shared Neighborhood Hits	83
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

SOX5_MOUSE
NC score	0.455193 (rank : 64)	θ value	0.00298849 (rank : 65)
Query Neighborhood Hits	126	Target Neighborhood Hits	196	Shared Neighborhood Hits	82
SwissProt Accessions	P35710, O88184, O89018	Gene names	Sox5, Sox-5
Domain Architecture
Description	Transcription factor SOX-5.

SOX5_HUMAN
NC score	0.453690 (rank : 65)	θ value	0.00298849 (rank : 64)
Query Neighborhood Hits	126	Target Neighborhood Hits	219	Shared Neighborhood Hits	82
SwissProt Accessions	P35711, Q86UK8, Q8J017, Q8J018, Q8J019, Q8J020, Q8N1D9, Q8N7E0, Q8TEA4	Gene names	SOX5
Domain Architecture
Description	Transcription factor SOX-5.

SOX13_HUMAN
NC score	0.452433 (rank : 66)	θ value	0.000786445 (rank : 49)
Query Neighborhood Hits	126	Target Neighborhood Hits	464	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

HBP1_HUMAN
NC score	0.444937 (rank : 67)	θ value	0.00175202 (rank : 58)
Query Neighborhood Hits	126	Target Neighborhood Hits	89	Shared Neighborhood Hits	74
SwissProt Accessions	O60381, Q8TBM1, Q8TE93, Q96AJ2	Gene names	HBP1
Domain Architecture	No domain graphic available
Description	HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1).

HBP1_MOUSE
NC score	0.443905 (rank : 68)	θ value	0.00175202 (rank : 59)
Query Neighborhood Hits	126	Target Neighborhood Hits	86	Shared Neighborhood Hits	74
SwissProt Accessions	Q8R316, Q3V0I4, Q8BUS3, Q8C199	Gene names	Hbp1
Domain Architecture	No domain graphic available
Description	HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1).

CIC_MOUSE
NC score	0.437690 (rank : 69)	θ value	0.000461057 (rank : 46)
Query Neighborhood Hits	126	Target Neighborhood Hits	742	Shared Neighborhood Hits	80
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CIC_HUMAN
NC score	0.413080 (rank : 70)	θ value	0.000461057 (rank : 45)
Query Neighborhood Hits	126	Target Neighborhood Hits	992	Shared Neighborhood Hits	82
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

SMCE1_HUMAN
NC score	0.395827 (rank : 71)	θ value	0.163984 (rank : 76)
Query Neighborhood Hits	126	Target Neighborhood Hits	272	Shared Neighborhood Hits	82
SwissProt Accessions	Q969G3, O43539	Gene names	SMARCE1, BAF57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 (BRG1-associated factor 57).

PMS1_HUMAN
NC score	0.393637 (rank : 72)	θ value	6.43352e-06 (rank : 25)
Query Neighborhood Hits	126	Target Neighborhood Hits	126	Shared Neighborhood Hits	69
SwissProt Accessions	P54277	Gene names	PMS1, PMSL1
Domain Architecture
Description	PMS1 protein homolog 1 (DNA mismatch repair protein PMS1).

SMCE1_MOUSE
NC score	0.374114 (rank : 73)	θ value	0.163984 (rank : 77)
Query Neighborhood Hits	126	Target Neighborhood Hits	409	Shared Neighborhood Hits	84
SwissProt Accessions	O54941, Q8BPD9	Gene names	Smarce1, Baf57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator chromatin subfamily E member 1 (BRG1-associated factor 57).

PB1_HUMAN
NC score	0.354049 (rank : 74)	θ value	0.00228821 (rank : 61)
Query Neighborhood Hits	126	Target Neighborhood Hits	261	Shared Neighborhood Hits	81
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

TCF7_HUMAN
NC score	0.292221 (rank : 75)	θ value	1.38821 (rank : 88)
Query Neighborhood Hits	126	Target Neighborhood Hits	186	Shared Neighborhood Hits	69
SwissProt Accessions	P36402, Q9UKI4	Gene names	TCF7, TCF1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

TCF7_MOUSE
NC score	0.278323 (rank : 76)	θ value	0.0961366 (rank : 74)
Query Neighborhood Hits	126	Target Neighborhood Hits	277	Shared Neighborhood Hits	66
SwissProt Accessions	Q00417	Gene names	Tcf7, Tcf-1, Tcf1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

LEF1_HUMAN
NC score	0.269755 (rank : 77)	θ value	0.813845 (rank : 84)
Query Neighborhood Hits	126	Target Neighborhood Hits	150	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UJU2, Q9HAZ0	Gene names	LEF1
Domain Architecture
Description	Lymphoid enhancer-binding factor 1 (LEF-1) (T cell-specific transcription factor 1-alpha) (TCF1-alpha).

LEF1_MOUSE
NC score	0.269207 (rank : 78)	θ value	0.813845 (rank : 85)
Query Neighborhood Hits	126	Target Neighborhood Hits	161	Shared Neighborhood Hits	74
SwissProt Accessions	P27782	Gene names	Lef1, Lef-1
Domain Architecture
Description	Lymphoid enhancer-binding factor 1 (LEF-1).

TF7L2_MOUSE
NC score	0.243634 (rank : 79)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	126	Target Neighborhood Hits	95	Shared Neighborhood Hits	67
SwissProt Accessions	Q924A0, O70574, Q91XP2, Q91XP3, Q91XP4, Q924A1, Q9Z0V3, Q9Z0V4	Gene names	Tcf7l2, Tcf4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (mTCF-4).

TF7L2_HUMAN
NC score	0.242192 (rank : 80)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	126	Target Neighborhood Hits	119	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NQB0, O00185, Q9NQB1, Q9NQB2, Q9NQB3, Q9NQB4, Q9NQB5, Q9NQB6, Q9NQB7, Q9ULC2	Gene names	TCF7L2, TCF4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (hTCF-4).

TF7L1_HUMAN
NC score	0.238822 (rank : 81)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	126	Target Neighborhood Hits	129	Shared Neighborhood Hits	67
SwissProt Accessions	Q9HCS4, Q53R97, Q6PD70, Q9NP00	Gene names	TCF7L1, TCF3
Domain Architecture
Description	Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF- 3).

TF7L1_MOUSE
NC score	0.238534 (rank : 82)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	126	Target Neighborhood Hits	131	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Z1J1, O70450, O70573	Gene names	Tcf7l1, Tcf3
Domain Architecture
Description	Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF-3) (mTCF-3).

SP100_MOUSE
NC score	0.100075 (rank : 83)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	126	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	O35892, O35897, O88392, O88395	Gene names	Sp100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein).

S100R_MOUSE
NC score	0.092506 (rank : 84)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	126	Target Neighborhood Hits	11	Shared Neighborhood Hits	1
SwissProt Accessions	Q99388	Gene names	D1Lub1, Sp100-rs
Domain Architecture
Description	Putative Sp100-related protein.

LY10_HUMAN
NC score	0.085570 (rank : 85)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	126	Target Neighborhood Hits	151	Shared Neighborhood Hits	6
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

IPR1_MOUSE
NC score	0.068026 (rank : 86)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	126	Target Neighborhood Hits	65	Shared Neighborhood Hits	1
SwissProt Accessions	Q8BVK9, Q3UCV7, Q80V00	Gene names	Ipr1, Ifi75
Domain Architecture	No domain graphic available
Description	Intracellular pathogen resistance protein 1.

SEC62_MOUSE
NC score	0.067691 (rank : 87)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	126	Target Neighborhood Hits	101	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BU14, Q6NX81	Gene names	Tloc1, Sec62
Domain Architecture	No domain graphic available
Description	Translocation protein SEC62 (Translocation protein 1) (TP-1).

LEO1_MOUSE
NC score	0.066413 (rank : 88)	θ value	0.0961366 (rank : 73)
Query Neighborhood Hits	126	Target Neighborhood Hits	946	Shared Neighborhood Hits	41
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

SP110_HUMAN
NC score	0.060286 (rank : 89)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	126	Target Neighborhood Hits	141	Shared Neighborhood Hits	7
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

SEC63_HUMAN
NC score	0.053208 (rank : 90)	θ value	0.279714 (rank : 79)
Query Neighborhood Hits	126	Target Neighborhood Hits	586	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

SEC62_HUMAN
NC score	0.051243 (rank : 91)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	126	Target Neighborhood Hits	100	Shared Neighborhood Hits	19
SwissProt Accessions	Q99442, O00682, O00729	Gene names	TLOC1, SEC62
Domain Architecture	No domain graphic available
Description	Translocation protein SEC62 (Translocation protein 1) (TP-1) (hTP-1).

SEC63_MOUSE
NC score	0.049742 (rank : 92)	θ value	0.279714 (rank : 80)
Query Neighborhood Hits	126	Target Neighborhood Hits	601	Shared Neighborhood Hits	22
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

NSBP1_MOUSE
NC score	0.046882 (rank : 93)	θ value	0.47712 (rank : 82)
Query Neighborhood Hits	126	Target Neighborhood Hits	681	Shared Neighborhood Hits	31
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

LEO1_HUMAN
NC score	0.046160 (rank : 94)	θ value	3.0926 (rank : 97)
Query Neighborhood Hits	126	Target Neighborhood Hits	958	Shared Neighborhood Hits	38
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

ENKUR_MOUSE
NC score	0.043548 (rank : 95)	θ value	0.62314 (rank : 83)
Query Neighborhood Hits	126	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	Q6SP97	Gene names
Domain Architecture	No domain graphic available
Description	Enkurin.

PHF20_HUMAN
NC score	0.040234 (rank : 96)	θ value	1.38821 (rank : 86)
Query Neighborhood Hits	126	Target Neighborhood Hits	394	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

CF010_HUMAN
NC score	0.039355 (rank : 97)	θ value	1.81305 (rank : 90)
Query Neighborhood Hits	126	Target Neighborhood Hits	329	Shared Neighborhood Hits	17
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

ERIC1_HUMAN
NC score	0.039144 (rank : 98)	θ value	8.99809 (rank : 121)
Query Neighborhood Hits	126	Target Neighborhood Hits	364	Shared Neighborhood Hits	20
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

MATR3_HUMAN
NC score	0.038866 (rank : 99)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	126	Target Neighborhood Hits	325	Shared Neighborhood Hits	19
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

MATR3_MOUSE
NC score	0.037843 (rank : 100)	θ value	3.0926 (rank : 98)
Query Neighborhood Hits	126	Target Neighborhood Hits	321	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

MDN1_HUMAN
NC score	0.036653 (rank : 101)	θ value	1.81305 (rank : 91)
Query Neighborhood Hits	126	Target Neighborhood Hits	662	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

PHF20_MOUSE
NC score	0.035628 (rank : 102)	θ value	2.36792 (rank : 95)
Query Neighborhood Hits	126	Target Neighborhood Hits	513	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

TXND2_MOUSE
NC score	0.032503 (rank : 103)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	126	Target Neighborhood Hits	828	Shared Neighborhood Hits	32
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

SMRC1_MOUSE
NC score	0.031842 (rank : 104)	θ value	1.38821 (rank : 87)
Query Neighborhood Hits	126	Target Neighborhood Hits	459	Shared Neighborhood Hits	32
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

DNMT1_HUMAN
NC score	0.030990 (rank : 105)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	126	Target Neighborhood Hits	401	Shared Neighborhood Hits	28
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

NPBL_MOUSE
NC score	0.030987 (rank : 106)	θ value	4.03905 (rank : 103)
Query Neighborhood Hits	126	Target Neighborhood Hits	1041	Shared Neighborhood Hits	44
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

TGON2_HUMAN
NC score	0.029294 (rank : 107)	θ value	1.38821 (rank : 89)
Query Neighborhood Hits	126	Target Neighborhood Hits	1037	Shared Neighborhood Hits	30
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

RBBP6_MOUSE
NC score	0.027704 (rank : 108)	θ value	3.0926 (rank : 100)
Query Neighborhood Hits	126	Target Neighborhood Hits	1014	Shared Neighborhood Hits	35
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

MLL3_HUMAN
NC score	0.027465 (rank : 109)	θ value	3.0926 (rank : 99)
Query Neighborhood Hits	126	Target Neighborhood Hits	1644	Shared Neighborhood Hits	34
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

IMB3_MOUSE
NC score	0.024510 (rank : 110)	θ value	2.36792 (rank : 94)
Query Neighborhood Hits	126	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BKC5, Q3TEG2, Q7TQC6, Q9EQ30	Gene names	Ranbp5, Kpnb3
Domain Architecture
Description	Importin beta-3 (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5).

IMB3_HUMAN
NC score	0.024503 (rank : 111)	θ value	2.36792 (rank : 93)
Query Neighborhood Hits	126	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	O00410, O15257	Gene names	RANBP5, KPNB3
Domain Architecture
Description	Importin beta-3 (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5).

VPS72_HUMAN
NC score	0.024306 (rank : 112)	θ value	5.27518 (rank : 113)
Query Neighborhood Hits	126	Target Neighborhood Hits	274	Shared Neighborhood Hits	14
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

VPS72_MOUSE
NC score	0.024203 (rank : 113)	θ value	5.27518 (rank : 114)
Query Neighborhood Hits	126	Target Neighborhood Hits	286	Shared Neighborhood Hits	14
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

CEBPZ_MOUSE
NC score	0.023355 (rank : 114)	θ value	4.03905 (rank : 101)
Query Neighborhood Hits	126	Target Neighborhood Hits	60	Shared Neighborhood Hits	7
SwissProt Accessions	P53569, Q3TXW5, Q3TYA8, Q3UWQ7	Gene names	Cebpz, Cbf2, Cebpa-rs1
Domain Architecture
Description	CCAAT/enhancer-binding protein zeta (CCAAT-box-binding transcription factor) (CCAAT-binding factor) (CBF).

CAN3_MOUSE
NC score	0.021661 (rank : 115)	θ value	0.163984 (rank : 75)
Query Neighborhood Hits	126	Target Neighborhood Hits	115	Shared Neighborhood Hits	6
SwissProt Accessions	Q64691, Q9WUC5	Gene names	Capn3
Domain Architecture
Description	Calpain-3 (EC 3.4.22.-) (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3).

NUFP1_HUMAN
NC score	0.019222 (rank : 116)	θ value	4.03905 (rank : 104)
Query Neighborhood Hits	126	Target Neighborhood Hits	193	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UHK0, Q8WVM5, Q96SG1	Gene names	NUFIP1
Domain Architecture	No domain graphic available
Description	Nuclear fragile X mental retardation-interacting protein 1 (Nuclear FMRP-interacting protein 1).

IF2B_HUMAN
NC score	0.018819 (rank : 117)	θ value	5.27518 (rank : 109)
Query Neighborhood Hits	126	Target Neighborhood Hits	60	Shared Neighborhood Hits	6
SwissProt Accessions	P20042, Q9BVU0, Q9UJE4	Gene names	EIF2S2, EIF2B
Domain Architecture
Description	Eukaryotic translation initiation factor 2 subunit 2 (Eukaryotic translation initiation factor 2 subunit beta) (eIF-2-beta).

GAS7_MOUSE
NC score	0.018315 (rank : 118)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	126	Target Neighborhood Hits	259	Shared Neighborhood Hits	11
SwissProt Accessions	Q60780, Q9QY25, Q9QY26, Q9QY34	Gene names	Gas7
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

OSBL8_HUMAN
NC score	0.017826 (rank : 119)	θ value	4.03905 (rank : 105)
Query Neighborhood Hits	126	Target Neighborhood Hits	289	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

PLCB3_MOUSE
NC score	0.016253 (rank : 120)	θ value	2.36792 (rank : 96)
Query Neighborhood Hits	126	Target Neighborhood Hits	344	Shared Neighborhood Hits	10
SwissProt Accessions	P51432	Gene names	Plcb3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

MY18A_MOUSE
NC score	0.015694 (rank : 121)	θ value	0.279714 (rank : 78)
Query Neighborhood Hits	126	Target Neighborhood Hits	1989	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

BPTF_HUMAN
NC score	0.014446 (rank : 122)	θ value	8.99809 (rank : 119)
Query Neighborhood Hits	126	Target Neighborhood Hits	786	Shared Neighborhood Hits	29
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

CCD46_HUMAN
NC score	0.014427 (rank : 123)	θ value	2.36792 (rank : 92)
Query Neighborhood Hits	126	Target Neighborhood Hits	1430	Shared Neighborhood Hits	32
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

AN30A_HUMAN
NC score	0.014233 (rank : 124)	θ value	0.47712 (rank : 81)
Query Neighborhood Hits	126	Target Neighborhood Hits	1119	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

PSMD2_MOUSE
NC score	0.011763 (rank : 125)	θ value	4.03905 (rank : 106)
Query Neighborhood Hits	126	Target Neighborhood Hits	147	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VDM4	Gene names	Psmd2
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97).

GAS7_HUMAN
NC score	0.011397 (rank : 126)	θ value	8.99809 (rank : 123)
Query Neighborhood Hits	126	Target Neighborhood Hits	258	Shared Neighborhood Hits	10
SwissProt Accessions	O60861, O43144	Gene names	GAS7, KIAA0394
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

MY18A_HUMAN
NC score	0.010803 (rank : 127)	θ value	4.03905 (rank : 102)
Query Neighborhood Hits	126	Target Neighborhood Hits	1929	Shared Neighborhood Hits	32
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

RM46_HUMAN
NC score	0.008815 (rank : 128)	θ value	8.99809 (rank : 124)
Query Neighborhood Hits	126	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H2W6, Q9HBU8	Gene names	MRPL46, C15orf4, LIECG2
Domain Architecture	No domain graphic available
Description	39S ribosomal protein L46, mitochondrial precursor (L46mt) (MRP-L46) (P2ECSL).

CK5P2_HUMAN
NC score	0.006752 (rank : 129)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	126	Target Neighborhood Hits	1433	Shared Neighborhood Hits	25
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

SMC2_MOUSE
NC score	0.006425 (rank : 130)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	126	Target Neighborhood Hits	1131	Shared Neighborhood Hits	21
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

FLIP1_MOUSE
NC score	0.005461 (rank : 131)	θ value	8.99809 (rank : 122)
Query Neighborhood Hits	126	Target Neighborhood Hits	1176	Shared Neighborhood Hits	16
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

CD2L5_HUMAN
NC score	-0.003339 (rank : 132)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	126	Target Neighborhood Hits	987	Shared Neighborhood Hits	11
SwissProt Accessions	Q14004, Q6DKQ9, Q75MH4, Q75MH5, Q96JN4, Q9H4A0, Q9H4A1, Q9UDR4	Gene names	CDC2L5, CDC2L, CHED, KIAA1791
Domain Architecture
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5) (Cholinesterase-related cell division controller).

ZBT10_HUMAN
NC score	-0.003855 (rank : 133)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	126	Target Neighborhood Hits	831	Shared Neighborhood Hits	5
SwissProt Accessions	Q96DT7, Q86W96, Q8IXI9, Q96MH9	Gene names	ZBTB10, RINZF, RINZFC
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 10 (Zinc finger protein RIN ZF).

CD2L5_MOUSE
NC score	-0.003993 (rank : 134)	θ value	8.99809 (rank : 120)
Query Neighborhood Hits	126	Target Neighborhood Hits	1011	Shared Neighborhood Hits	12
SwissProt Accessions	Q69ZA1, Q80V11, Q8BZG1, Q8K0A4	Gene names	Cdc2l5, Kiaa1791
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5).