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Network neighborhood for query Sequence : SOX8_HUMAN

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SOX8_HUMAN
SwissProt Accessions	P57073, Q9NZW2	Gene names	SOX8
Domain Architecture
Description	Transcription factor SOX-8.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SOX8_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	100	Target Neighborhood Hits	100	Shared Neighborhood Hits	100
SwissProt Accessions	P57073, Q9NZW2	Gene names	SOX8
Domain Architecture
Description	Transcription factor SOX-8.

SOX8_MOUSE
θ value	2.26584e-152 (rank : 2)	NC score	0.997400 (rank : 2)
Query Neighborhood Hits	100	Target Neighborhood Hits	96	Shared Neighborhood Hits	81
SwissProt Accessions	Q04886	Gene names	Sox8, Sox-8
Domain Architecture
Description	Transcription factor SOX-8.

SOX9_MOUSE
θ value	2.54619e-95 (rank : 3)	NC score	0.978037 (rank : 5)
Query Neighborhood Hits	100	Target Neighborhood Hits	188	Shared Neighborhood Hits	78
SwissProt Accessions	Q04887, Q8C7L2, Q91ZK2, Q99KQ0	Gene names	Sox9, Sox-9
Domain Architecture
Description	Transcription factor SOX-9.

SOX9_HUMAN
θ value	1.65039e-94 (rank : 4)	NC score	0.976107 (rank : 6)
Query Neighborhood Hits	100	Target Neighborhood Hits	210	Shared Neighborhood Hits	79
SwissProt Accessions	P48436	Gene names	SOX9
Domain Architecture
Description	Transcription factor SOX-9.

SOX10_HUMAN
θ value	1.59853e-89 (rank : 5)	NC score	0.982453 (rank : 3)
Query Neighborhood Hits	100	Target Neighborhood Hits	122	Shared Neighborhood Hits	74
SwissProt Accessions	P56693	Gene names	SOX10
Domain Architecture
Description	Transcription factor SOX-10.

SOX10_MOUSE
θ value	4.81303e-86 (rank : 6)	NC score	0.982438 (rank : 4)
Query Neighborhood Hits	100	Target Neighborhood Hits	110	Shared Neighborhood Hits	74
SwissProt Accessions	Q04888, O08518, O09141, O54856, P70416	Gene names	Sox10, Sox-10, Sox21
Domain Architecture
Description	Transcription factor SOX-10 (SOX-21) (Transcription factor SOX-M).

SOX17_MOUSE
θ value	4.89182e-30 (rank : 7)	NC score	0.919133 (rank : 30)
Query Neighborhood Hits	100	Target Neighborhood Hits	223	Shared Neighborhood Hits	79
SwissProt Accessions	Q61473, Q61472, Q62248	Gene names	Sox17, Sox-17
Domain Architecture
Description	Transcription factor SOX-17.

SOX17_HUMAN
θ value	8.3442e-30 (rank : 8)	NC score	0.930526 (rank : 24)
Query Neighborhood Hits	100	Target Neighborhood Hits	108	Shared Neighborhood Hits	76
SwissProt Accessions	Q9H6I2	Gene names	SOX17
Domain Architecture
Description	Transcription factor SOX-17.

SOX1_HUMAN
θ value	4.14116e-29 (rank : 9)	NC score	0.933185 (rank : 19)
Query Neighborhood Hits	100	Target Neighborhood Hits	90	Shared Neighborhood Hits	78
SwissProt Accessions	O00570	Gene names	SOX1
Domain Architecture
Description	SOX-1 protein.

SOX1_MOUSE
θ value	9.2256e-29 (rank : 10)	NC score	0.931974 (rank : 23)
Query Neighborhood Hits	100	Target Neighborhood Hits	90	Shared Neighborhood Hits	77
SwissProt Accessions	P53783	Gene names	Sox1, Sox-1
Domain Architecture
Description	SOX-1 protein.

SOX4_HUMAN
θ value	2.05525e-28 (rank : 11)	NC score	0.940738 (rank : 13)
Query Neighborhood Hits	100	Target Neighborhood Hits	111	Shared Neighborhood Hits	77
SwissProt Accessions	Q06945	Gene names	SOX4
Domain Architecture
Description	Transcription factor SOX-4.

SOX21_HUMAN
θ value	7.80994e-28 (rank : 12)	NC score	0.942512 (rank : 11)
Query Neighborhood Hits	100	Target Neighborhood Hits	89	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y651, P35715, Q15504	Gene names	SOX21, SOX25, SOXA
Domain Architecture
Description	Transcription factor SOX-21 (SOX-A).

SOX21_MOUSE
θ value	7.80994e-28 (rank : 13)	NC score	0.942535 (rank : 10)
Query Neighborhood Hits	100	Target Neighborhood Hits	90	Shared Neighborhood Hits	77
SwissProt Accessions	Q811W0, Q8VH35	Gene names	Sox21
Domain Architecture	No domain graphic available
Description	Transcription factor SOX-21.

SOX4_MOUSE
θ value	1.33217e-27 (rank : 14)	NC score	0.938365 (rank : 15)
Query Neighborhood Hits	100	Target Neighborhood Hits	108	Shared Neighborhood Hits	77
SwissProt Accessions	Q06831	Gene names	Sox4, Sox-4
Domain Architecture
Description	Transcription factor SOX-4.

SOX12_HUMAN
θ value	2.96777e-27 (rank : 15)	NC score	0.955368 (rank : 8)
Query Neighborhood Hits	100	Target Neighborhood Hits	111	Shared Neighborhood Hits	76
SwissProt Accessions	O15370, Q9NUD4	Gene names	SOX12, SOX22
Domain Architecture
Description	SOX-12 protein (SOX-22 protein).

SOX14_HUMAN
θ value	2.96777e-27 (rank : 16)	NC score	0.933028 (rank : 21)
Query Neighborhood Hits	100	Target Neighborhood Hits	102	Shared Neighborhood Hits	77
SwissProt Accessions	O95416, Q3KPH7	Gene names	SOX14, SOX28
Domain Architecture
Description	Transcription factor SOX-14.

SOX14_MOUSE
θ value	2.96777e-27 (rank : 17)	NC score	0.933155 (rank : 20)
Query Neighborhood Hits	100	Target Neighborhood Hits	100	Shared Neighborhood Hits	77
SwissProt Accessions	Q04892, Q9JLC9, Q9JLD0, Q9QXU4	Gene names	Sox14, Sox-14
Domain Architecture
Description	Transcription factor SOX-14.

SOX18_HUMAN
θ value	2.96777e-27 (rank : 18)	NC score	0.935354 (rank : 18)
Query Neighborhood Hits	100	Target Neighborhood Hits	106	Shared Neighborhood Hits	79
SwissProt Accessions	P35713, Q9NPH8	Gene names	SOX18
Domain Architecture
Description	Transcription factor SOX-18.

SOX12_MOUSE
θ value	3.87602e-27 (rank : 19)	NC score	0.958092 (rank : 7)
Query Neighborhood Hits	100	Target Neighborhood Hits	98	Shared Neighborhood Hits	76
SwissProt Accessions	Q04890, P70417, Q6NXL2	Gene names	Sox12, Sox-12
Domain Architecture	No domain graphic available
Description	SOX-12 protein.

SOX18_MOUSE
θ value	3.87602e-27 (rank : 20)	NC score	0.935938 (rank : 17)
Query Neighborhood Hits	100	Target Neighborhood Hits	105	Shared Neighborhood Hits	77
SwissProt Accessions	P43680, Q9EQ73	Gene names	Sox18, Sox-18
Domain Architecture
Description	Transcription factor SOX-18.

SOX2_HUMAN
θ value	6.61148e-27 (rank : 21)	NC score	0.926339 (rank : 26)
Query Neighborhood Hits	100	Target Neighborhood Hits	89	Shared Neighborhood Hits	77
SwissProt Accessions	P48431, Q14537	Gene names	SOX2
Domain Architecture
Description	Transcription factor SOX-2.

SOX2_MOUSE
θ value	6.61148e-27 (rank : 22)	NC score	0.926020 (rank : 27)
Query Neighborhood Hits	100	Target Neighborhood Hits	90	Shared Neighborhood Hits	77
SwissProt Accessions	P48432	Gene names	Sox2, Sox-2
Domain Architecture
Description	Transcription factor SOX-2.

SOX15_HUMAN
θ value	8.63488e-27 (rank : 23)	NC score	0.937498 (rank : 16)
Query Neighborhood Hits	100	Target Neighborhood Hits	134	Shared Neighborhood Hits	77
SwissProt Accessions	O60248, P35717, Q9Y6W7	Gene names	SOX15, SOX12, SOX20, SOX26, SOX27
Domain Architecture
Description	SOX-15 protein (SOX-20 protein) (SOX-12 protein).

SOX11_HUMAN
θ value	1.12775e-26 (rank : 24)	NC score	0.943293 (rank : 9)
Query Neighborhood Hits	100	Target Neighborhood Hits	89	Shared Neighborhood Hits	77
SwissProt Accessions	P35716	Gene names	SOX11
Domain Architecture
Description	Transcription factor SOX-11.

SOX3_MOUSE
θ value	1.12775e-26 (rank : 25)	NC score	0.928568 (rank : 25)
Query Neighborhood Hits	100	Target Neighborhood Hits	101	Shared Neighborhood Hits	77
SwissProt Accessions	P53784	Gene names	Sox3, Sox-3
Domain Architecture
Description	Transcription factor SOX-3.

SOX11_MOUSE
θ value	1.92365e-26 (rank : 26)	NC score	0.940485 (rank : 14)
Query Neighborhood Hits	100	Target Neighborhood Hits	96	Shared Neighborhood Hits	78
SwissProt Accessions	Q7M6Y2, O35178, O89036, Q04889, Q80XF0	Gene names	Sox11, Sox-11
Domain Architecture	No domain graphic available
Description	Transcription factor SOX-11.

SOX7_HUMAN
θ value	3.28125e-26 (rank : 27)	NC score	0.915241 (rank : 32)
Query Neighborhood Hits	100	Target Neighborhood Hits	140	Shared Neighborhood Hits	77
SwissProt Accessions	Q9BT81	Gene names	SOX7
Domain Architecture
Description	Transcription factor SOX-7.

SOX7_MOUSE
θ value	4.28545e-26 (rank : 28)	NC score	0.921081 (rank : 29)
Query Neighborhood Hits	100	Target Neighborhood Hits	105	Shared Neighborhood Hits	76
SwissProt Accessions	P40646, Q9R1T6	Gene names	Sox7, Sox-7
Domain Architecture
Description	Transcription factor SOX-7 (mSOX7).

SOX15_MOUSE
θ value	5.59698e-26 (rank : 29)	NC score	0.940856 (rank : 12)
Query Neighborhood Hits	100	Target Neighborhood Hits	100	Shared Neighborhood Hits	78
SwissProt Accessions	P43267, O70204, P70418, Q62246, Q91V00, Q91V43, Q920T1, Q9JLG2	Gene names	Sox15, Sox-15
Domain Architecture
Description	SOX-15 protein.

SOX3_HUMAN
θ value	1.62847e-25 (rank : 30)	NC score	0.923992 (rank : 28)
Query Neighborhood Hits	100	Target Neighborhood Hits	109	Shared Neighborhood Hits	78
SwissProt Accessions	P41225, P35714, Q9NP49	Gene names	SOX3
Domain Architecture
Description	Transcription factor SOX-3.

SRY_MOUSE
θ value	1.6852e-22 (rank : 31)	NC score	0.916945 (rank : 31)
Query Neighborhood Hits	100	Target Neighborhood Hits	139	Shared Neighborhood Hits	77
SwissProt Accessions	Q05738	Gene names	Sry, Tdf, Tdy
Domain Architecture
Description	Sex-determining region Y protein (Testis-determining factor).

SOX5_HUMAN
θ value	9.24701e-21 (rank : 32)	NC score	0.833054 (rank : 34)
Query Neighborhood Hits	100	Target Neighborhood Hits	219	Shared Neighborhood Hits	77
SwissProt Accessions	P35711, Q86UK8, Q8J017, Q8J018, Q8J019, Q8J020, Q8N1D9, Q8N7E0, Q8TEA4	Gene names	SOX5
Domain Architecture
Description	Transcription factor SOX-5.

SOX5_MOUSE
θ value	9.24701e-21 (rank : 33)	NC score	0.835551 (rank : 33)
Query Neighborhood Hits	100	Target Neighborhood Hits	196	Shared Neighborhood Hits	75
SwissProt Accessions	P35710, O88184, O89018	Gene names	Sox5, Sox-5
Domain Architecture
Description	Transcription factor SOX-5.

SOX6_HUMAN
θ value	2.69047e-20 (rank : 34)	NC score	0.815247 (rank : 35)
Query Neighborhood Hits	100	Target Neighborhood Hits	332	Shared Neighborhood Hits	78
SwissProt Accessions	P35712, Q9BXQ3, Q9BXQ4, Q9BXQ5, Q9H0I8	Gene names	SOX6
Domain Architecture
Description	Transcription factor SOX-6.

SOX6_MOUSE
θ value	2.69047e-20 (rank : 35)	NC score	0.814339 (rank : 36)
Query Neighborhood Hits	100	Target Neighborhood Hits	341	Shared Neighborhood Hits	79
SwissProt Accessions	P40645, Q62250, Q9QWS5	Gene names	Sox6, Sox-6
Domain Architecture
Description	Transcription factor SOX-6 (SOX-LZ).

SOX13_HUMAN
θ value	7.82807e-20 (rank : 36)	NC score	0.806516 (rank : 39)
Query Neighborhood Hits	100	Target Neighborhood Hits	464	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

SOX13_MOUSE
θ value	7.82807e-20 (rank : 37)	NC score	0.809369 (rank : 37)
Query Neighborhood Hits	100	Target Neighborhood Hits	495	Shared Neighborhood Hits	81
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

SRY_HUMAN
θ value	1.74391e-19 (rank : 38)	NC score	0.932142 (rank : 22)
Query Neighborhood Hits	100	Target Neighborhood Hits	83	Shared Neighborhood Hits	77
SwissProt Accessions	Q05066	Gene names	SRY, TDF
Domain Architecture
Description	Sex-determining region Y protein (Testis-determining factor).

SOX30_HUMAN
θ value	3.07829e-16 (rank : 39)	NC score	0.804763 (rank : 40)
Query Neighborhood Hits	100	Target Neighborhood Hits	305	Shared Neighborhood Hits	78
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

SOX30_MOUSE
θ value	3.07829e-16 (rank : 40)	NC score	0.806971 (rank : 38)
Query Neighborhood Hits	100	Target Neighborhood Hits	374	Shared Neighborhood Hits	79
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

CIC_MOUSE
θ value	3.89403e-11 (rank : 41)	NC score	0.651190 (rank : 43)
Query Neighborhood Hits	100	Target Neighborhood Hits	742	Shared Neighborhood Hits	79
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CIC_HUMAN
θ value	1.9326e-10 (rank : 42)	NC score	0.611579 (rank : 49)
Query Neighborhood Hits	100	Target Neighborhood Hits	992	Shared Neighborhood Hits	80
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

HMGB3_MOUSE
θ value	1.38499e-08 (rank : 43)	NC score	0.621930 (rank : 48)
Query Neighborhood Hits	100	Target Neighborhood Hits	88	Shared Neighborhood Hits	69
SwissProt Accessions	O54879	Gene names	Hmgb3, Hmg2a, Hmg4
Domain Architecture
Description	High mobility group protein B3 (High mobility group protein 4) (HMG-4) (High mobility group protein 2a) (HMG-2a).

TF7L2_HUMAN
θ value	1.38499e-08 (rank : 44)	NC score	0.589894 (rank : 52)
Query Neighborhood Hits	100	Target Neighborhood Hits	119	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NQB0, O00185, Q9NQB1, Q9NQB2, Q9NQB3, Q9NQB4, Q9NQB5, Q9NQB6, Q9NQB7, Q9ULC2	Gene names	TCF7L2, TCF4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (hTCF-4).

TF7L2_MOUSE
θ value	1.38499e-08 (rank : 45)	NC score	0.593206 (rank : 51)
Query Neighborhood Hits	100	Target Neighborhood Hits	95	Shared Neighborhood Hits	65
SwissProt Accessions	Q924A0, O70574, Q91XP2, Q91XP3, Q91XP4, Q924A1, Q9Z0V3, Q9Z0V4	Gene names	Tcf7l2, Tcf4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (mTCF-4).

HMGB3_HUMAN
θ value	1.80886e-08 (rank : 46)	NC score	0.630936 (rank : 47)
Query Neighborhood Hits	100	Target Neighborhood Hits	86	Shared Neighborhood Hits	69
SwissProt Accessions	O15347, O95556, Q6NS40	Gene names	HMGB3, HMG2A, HMG4
Domain Architecture
Description	High mobility group protein B3 (High mobility group protein 4) (HMG-4) (High mobility group protein 2a) (HMG-2a).

SSRP1_MOUSE
θ value	1.53129e-07 (rank : 47)	NC score	0.589139 (rank : 53)
Query Neighborhood Hits	100	Target Neighborhood Hits	193	Shared Neighborhood Hits	78
SwissProt Accessions	Q08943, Q3U9Z2, Q3UJ75, Q4V9U4, Q8CGA6	Gene names	Ssrp1
Domain Architecture
Description	FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (Structure-specific recognition protein 1) (Recombination signal sequence recognition protein 1) (T160).

SSRP1_HUMAN
θ value	2.61198e-07 (rank : 48)	NC score	0.581913 (rank : 54)
Query Neighborhood Hits	100	Target Neighborhood Hits	187	Shared Neighborhood Hits	78
SwissProt Accessions	Q08945, Q5BJG8	Gene names	SSRP1, FACT80
Domain Architecture
Description	FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (FACT 80 kDa subunit) (FACTp80) (Chromatin- specific transcription elongation factor 80 kDa subunit) (Structure- specific recognition protein 1) (hSSRP1) (Recombination signal sequence recognition protein 1) (T160).

TCF7_MOUSE
θ value	2.61198e-07 (rank : 49)	NC score	0.598092 (rank : 50)
Query Neighborhood Hits	100	Target Neighborhood Hits	277	Shared Neighborhood Hits	69
SwissProt Accessions	Q00417	Gene names	Tcf7, Tcf-1, Tcf1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

HBP1_HUMAN
θ value	4.45536e-07 (rank : 50)	NC score	0.676325 (rank : 42)
Query Neighborhood Hits	100	Target Neighborhood Hits	89	Shared Neighborhood Hits	75
SwissProt Accessions	O60381, Q8TBM1, Q8TE93, Q96AJ2	Gene names	HBP1
Domain Architecture	No domain graphic available
Description	HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1).

HBP1_MOUSE
θ value	4.45536e-07 (rank : 51)	NC score	0.676354 (rank : 41)
Query Neighborhood Hits	100	Target Neighborhood Hits	86	Shared Neighborhood Hits	76
SwissProt Accessions	Q8R316, Q3V0I4, Q8BUS3, Q8C199	Gene names	Hbp1
Domain Architecture	No domain graphic available
Description	HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1).

TF7L1_HUMAN
θ value	5.81887e-07 (rank : 52)	NC score	0.573699 (rank : 58)
Query Neighborhood Hits	100	Target Neighborhood Hits	129	Shared Neighborhood Hits	68
SwissProt Accessions	Q9HCS4, Q53R97, Q6PD70, Q9NP00	Gene names	TCF7L1, TCF3
Domain Architecture
Description	Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF- 3).

LEF1_MOUSE
θ value	7.59969e-07 (rank : 53)	NC score	0.580185 (rank : 56)
Query Neighborhood Hits	100	Target Neighborhood Hits	161	Shared Neighborhood Hits	72
SwissProt Accessions	P27782	Gene names	Lef1, Lef-1
Domain Architecture
Description	Lymphoid enhancer-binding factor 1 (LEF-1).

TF7L1_MOUSE
θ value	7.59969e-07 (rank : 54)	NC score	0.576254 (rank : 57)
Query Neighborhood Hits	100	Target Neighborhood Hits	131	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Z1J1, O70450, O70573	Gene names	Tcf7l1, Tcf3
Domain Architecture
Description	Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF-3) (mTCF-3).

HMGB2_HUMAN
θ value	9.92553e-07 (rank : 55)	NC score	0.572916 (rank : 59)
Query Neighborhood Hits	100	Target Neighborhood Hits	114	Shared Neighborhood Hits	78
SwissProt Accessions	P26583	Gene names	HMGB2, HMG2
Domain Architecture
Description	High mobility group protein B2 (High mobility group protein 2) (HMG- 2).

LEF1_HUMAN
θ value	9.92553e-07 (rank : 56)	NC score	0.581349 (rank : 55)
Query Neighborhood Hits	100	Target Neighborhood Hits	150	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UJU2, Q9HAZ0	Gene names	LEF1
Domain Architecture
Description	Lymphoid enhancer-binding factor 1 (LEF-1) (T cell-specific transcription factor 1-alpha) (TCF1-alpha).

BBX_HUMAN
θ value	1.29631e-06 (rank : 57)	NC score	0.643229 (rank : 44)
Query Neighborhood Hits	100	Target Neighborhood Hits	167	Shared Neighborhood Hits	75
SwissProt Accessions	Q8WY36, Q2TAJ1, Q7L3J8, Q7LBY8, Q8NDB0, Q8WY35, Q9H0J6	Gene names	BBX, HBP2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

HMGB2_MOUSE
θ value	2.21117e-06 (rank : 58)	NC score	0.560980 (rank : 60)
Query Neighborhood Hits	100	Target Neighborhood Hits	111	Shared Neighborhood Hits	76
SwissProt Accessions	P30681, Q3UXT1, Q9EQD5	Gene names	Hmgb2, Hmg2
Domain Architecture
Description	High mobility group protein B2 (High mobility group protein 2) (HMG- 2).

BBX_MOUSE
θ value	2.88788e-06 (rank : 59)	NC score	0.633359 (rank : 45)
Query Neighborhood Hits	100	Target Neighborhood Hits	152	Shared Neighborhood Hits	74
SwissProt Accessions	Q8VBW5, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VI48, Q8VI49, Q8VI50, Q9CS94	Gene names	Bbx, Hbp2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

TCF7_HUMAN
θ value	3.77169e-06 (rank : 60)	NC score	0.633112 (rank : 46)
Query Neighborhood Hits	100	Target Neighborhood Hits	186	Shared Neighborhood Hits	70
SwissProt Accessions	P36402, Q9UKI4	Gene names	TCF7, TCF1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

UBF1_HUMAN
θ value	8.40245e-06 (rank : 61)	NC score	0.485125 (rank : 66)
Query Neighborhood Hits	100	Target Neighborhood Hits	415	Shared Neighborhood Hits	78
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

HMGB1_HUMAN
θ value	1.09739e-05 (rank : 62)	NC score	0.532764 (rank : 63)
Query Neighborhood Hits	100	Target Neighborhood Hits	126	Shared Neighborhood Hits	75
SwissProt Accessions	P09429, Q6IBE1	Gene names	HMGB1, HMG1
Domain Architecture
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

HMGB1_MOUSE
θ value	1.09739e-05 (rank : 63)	NC score	0.532878 (rank : 62)
Query Neighborhood Hits	100	Target Neighborhood Hits	123	Shared Neighborhood Hits	75
SwissProt Accessions	P63158, P07155, P27109, P27428	Gene names	Hmgb1, Hmg-1, Hmg1
Domain Architecture	No domain graphic available
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

UBF1_MOUSE
θ value	1.87187e-05 (rank : 64)	NC score	0.477161 (rank : 67)
Query Neighborhood Hits	100	Target Neighborhood Hits	419	Shared Neighborhood Hits	77
SwissProt Accessions	P25976	Gene names	Ubtf, Tcfubf, Ubf-1, Ubf1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1).

HMG1X_HUMAN
θ value	2.44474e-05 (rank : 65)	NC score	0.499482 (rank : 65)
Query Neighborhood Hits	100	Target Neighborhood Hits	97	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UGV6	Gene names	HMG1L10
Domain Architecture
Description	High mobility group protein 1-like 10 (HMG-1L10).

HM20B_HUMAN
θ value	9.29e-05 (rank : 66)	NC score	0.548427 (rank : 61)
Query Neighborhood Hits	100	Target Neighborhood Hits	126	Shared Neighborhood Hits	74
SwissProt Accessions	Q9P0W2, Q6IBP8, Q8NBD5, Q9HD21, Q9Y491, Q9Y4A2	Gene names	HMG20B, BRAF35, HMGX2, SMARCE1R
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (HMG domain protein HMG20B) (Structural DNA-binding protein BRAF35) (BRCA2- associated factor 35) (Sox-like transcriptional factor).

HM20B_MOUSE
θ value	0.00102713 (rank : 67)	NC score	0.527014 (rank : 64)
Query Neighborhood Hits	100	Target Neighborhood Hits	122	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Z104, Q9NSF7, Q9NSF8	Gene names	Hmg20b, Braf35, Hmgx2, Smarce1r
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (HMG domain protein HMG20B) (Structural DNA-binding protein BRAF35) (BRCA2- associated factor 35).

SP100_HUMAN
θ value	0.00390308 (rank : 68)	NC score	0.306579 (rank : 74)
Query Neighborhood Hits	100	Target Neighborhood Hits	117	Shared Neighborhood Hits	63
SwissProt Accessions	P23497, O75450, Q13343, Q96F70, Q96T24, Q96T95, Q9NP33, Q9UE32	Gene names	SP100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein) (Lysp100b).

HM2L1_HUMAN
θ value	0.00665767 (rank : 69)	NC score	0.458551 (rank : 68)
Query Neighborhood Hits	100	Target Neighborhood Hits	130	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UGU5, O75672, O75673, Q9UMT5	Gene names	HMG2L1, HMGBCG
Domain Architecture
Description	High mobility group protein 2-like 1 (Protein HMGBCG).

HM20A_HUMAN
θ value	0.00869519 (rank : 70)	NC score	0.449867 (rank : 69)
Query Neighborhood Hits	100	Target Neighborhood Hits	343	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NP66, Q53G31, Q9NSF6	Gene names	HMG20A, HMGX1
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein HMGX1).

HM20A_MOUSE
θ value	0.00869519 (rank : 71)	NC score	0.447900 (rank : 70)
Query Neighborhood Hits	100	Target Neighborhood Hits	348	Shared Neighborhood Hits	75
SwissProt Accessions	Q9DC33, Q3LSF9, Q6NV87, Q8BSK1, Q8C3C1, Q8CAA0, Q9CYG2	Gene names	Hmg20a, Ibraf
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (iBRAF) (Inhibitor of BRAF35) (HMG domain protein HMGX1).

PB1_HUMAN
θ value	0.00869519 (rank : 72)	NC score	0.283764 (rank : 76)
Query Neighborhood Hits	100	Target Neighborhood Hits	261	Shared Neighborhood Hits	77
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

EYA1_MOUSE
θ value	0.0330416 (rank : 73)	NC score	0.027916 (rank : 83)
Query Neighborhood Hits	100	Target Neighborhood Hits	108	Shared Neighborhood Hits	5
SwissProt Accessions	P97767, O08818	Gene names	Eya1
Domain Architecture
Description	Eyes absent homolog 1 (EC 3.1.3.48).

SMCE1_HUMAN
θ value	0.0736092 (rank : 74)	NC score	0.334707 (rank : 72)
Query Neighborhood Hits	100	Target Neighborhood Hits	272	Shared Neighborhood Hits	64
SwissProt Accessions	Q969G3, O43539	Gene names	SMARCE1, BAF57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 (BRG1-associated factor 57).

SMCE1_MOUSE
θ value	0.0736092 (rank : 75)	NC score	0.314604 (rank : 73)
Query Neighborhood Hits	100	Target Neighborhood Hits	409	Shared Neighborhood Hits	64
SwissProt Accessions	O54941, Q8BPD9	Gene names	Smarce1, Baf57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator chromatin subfamily E member 1 (BRG1-associated factor 57).

PMS1_HUMAN
θ value	0.21417 (rank : 76)	NC score	0.261380 (rank : 77)
Query Neighborhood Hits	100	Target Neighborhood Hits	126	Shared Neighborhood Hits	65
SwissProt Accessions	P54277	Gene names	PMS1, PMSL1
Domain Architecture
Description	PMS1 protein homolog 1 (DNA mismatch repair protein PMS1).

TFAM_MOUSE
θ value	0.365318 (rank : 77)	NC score	0.350347 (rank : 71)
Query Neighborhood Hits	100	Target Neighborhood Hits	93	Shared Neighborhood Hits	74
SwissProt Accessions	P40630, P97894, P97906, Q543I8, Q9DBM9	Gene names	Tfam, Hmgts
Domain Architecture
Description	Transcription factor A, mitochondrial precursor (mtTFA) (Testis- specific high mobility group protein) (TS-HMG).

ZN516_MOUSE
θ value	0.365318 (rank : 78)	NC score	0.006556 (rank : 94)
Query Neighborhood Hits	100	Target Neighborhood Hits	1197	Shared Neighborhood Hits	17
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

ZN516_HUMAN
θ value	0.47712 (rank : 79)	NC score	0.001995 (rank : 101)
Query Neighborhood Hits	100	Target Neighborhood Hits	854	Shared Neighborhood Hits	8
SwissProt Accessions	Q92618	Gene names	ZNF516, KIAA0222
Domain Architecture	No domain graphic available
Description	Zinc finger protein 516.

GCH1_HUMAN
θ value	1.06291 (rank : 80)	NC score	0.019848 (rank : 86)
Query Neighborhood Hits	100	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	P30793, Q9Y4I8	Gene names	GCH1, DYT5, GCH
Domain Architecture
Description	GTP cyclohydrolase I (EC 3.5.4.16) (GTP-CH-I).

WNK2_HUMAN
θ value	1.06291 (rank : 81)	NC score	0.002808 (rank : 100)
Query Neighborhood Hits	100	Target Neighborhood Hits	1407	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

CAC1A_HUMAN
θ value	1.38821 (rank : 82)	NC score	0.004218 (rank : 97)
Query Neighborhood Hits	100	Target Neighborhood Hits	387	Shared Neighborhood Hits	7
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

LCP2_HUMAN
θ value	1.38821 (rank : 83)	NC score	0.018781 (rank : 87)
Query Neighborhood Hits	100	Target Neighborhood Hits	531	Shared Neighborhood Hits	12
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

ECM1_HUMAN
θ value	2.36792 (rank : 84)	NC score	0.016395 (rank : 89)
Query Neighborhood Hits	100	Target Neighborhood Hits	182	Shared Neighborhood Hits	8
SwissProt Accessions	Q16610	Gene names	ECM1
Domain Architecture
Description	Extracellular matrix protein 1 precursor (Secretory component p85).

BCL9_HUMAN
θ value	3.0926 (rank : 85)	NC score	0.020024 (rank : 85)
Query Neighborhood Hits	100	Target Neighborhood Hits	1008	Shared Neighborhood Hits	21
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CPT1C_HUMAN
θ value	3.0926 (rank : 86)	NC score	0.009074 (rank : 92)
Query Neighborhood Hits	100	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TCG5, Q8N6Q9, Q8NDS6, Q8TE84	Gene names	CPT1C
Domain Architecture
Description	Carnitine O-palmitoyltransferase I, brain isoform (EC 2.3.1.21) (Carnitine palmitoyltransferase 1C) (CPT IC).

CPT1C_MOUSE
θ value	3.0926 (rank : 87)	NC score	0.009208 (rank : 91)
Query Neighborhood Hits	100	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BGD5	Gene names	Cpt1c
Domain Architecture
Description	Carnitine O-palmitoyltransferase I, brain isoform (EC 2.3.1.21) (Carnitine palmitoyltransferase 1C) (CPT IC).

ACES_HUMAN
θ value	4.03905 (rank : 88)	NC score	0.003475 (rank : 98)
Query Neighborhood Hits	100	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	P22303, Q16169, Q86TM9, Q9BXP7	Gene names	ACHE
Domain Architecture
Description	Acetylcholinesterase precursor (EC 3.1.1.7) (AChE).

HMX3_MOUSE
θ value	4.03905 (rank : 89)	NC score	-0.000250 (rank : 102)
Query Neighborhood Hits	100	Target Neighborhood Hits	342	Shared Neighborhood Hits	3
SwissProt Accessions	P42581	Gene names	Hmx3, Nkx-5.1, Nkx5-1
Domain Architecture
Description	Homeobox protein HMX3 (Homeobox protein Nkx-5.1).

MB3L2_HUMAN
θ value	4.03905 (rank : 90)	NC score	0.023600 (rank : 84)
Query Neighborhood Hits	100	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NHZ7	Gene names	MBD3L2
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3-like 2 (MBD3-like 2).

BORG1_HUMAN
θ value	5.27518 (rank : 91)	NC score	0.011339 (rank : 90)
Query Neighborhood Hits	100	Target Neighborhood Hits	67	Shared Neighborhood Hits	4
SwissProt Accessions	O14613, Q9UNS0	Gene names	CDC42EP2, BORG1, CEP2
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 2 (Binder of Rho GTPases 1).

KCNQ3_HUMAN
θ value	5.27518 (rank : 92)	NC score	0.003062 (rank : 99)
Query Neighborhood Hits	100	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

MLL2_HUMAN
θ value	5.27518 (rank : 93)	NC score	0.018543 (rank : 88)
Query Neighborhood Hits	100	Target Neighborhood Hits	1788	Shared Neighborhood Hits	25
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

TFAM_HUMAN
θ value	5.27518 (rank : 94)	NC score	0.291295 (rank : 75)
Query Neighborhood Hits	100	Target Neighborhood Hits	156	Shared Neighborhood Hits	58
SwissProt Accessions	Q00059	Gene names	TFAM, TCF6L2
Domain Architecture
Description	Transcription factor A, mitochondrial precursor (mtTFA) (Mitochondrial transcription factor 1) (MtTF1) (Transcription factor 6-like 2).

HXA1_MOUSE
θ value	6.88961 (rank : 95)	NC score	-0.001645 (rank : 103)
Query Neighborhood Hits	100	Target Neighborhood Hits	341	Shared Neighborhood Hits	3
SwissProt Accessions	P09022, P15463	Gene names	Hoxa1, Era-1, Hox-1.6, Hoxa-1
Domain Architecture
Description	Homeobox protein Hox-A1 (Hox-1.6) (Homeotic protein ERA-1-993) (Early retinoic acid 1) (Homeoboxless protein ERA-1-399).

K0141_HUMAN
θ value	6.88961 (rank : 96)	NC score	0.007810 (rank : 93)
Query Neighborhood Hits	100	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q14154, Q969R4, Q96EU9	Gene names	KIAA0141
Domain Architecture
Description	Protein KIAA0141.

RBL1_MOUSE
θ value	6.88961 (rank : 97)	NC score	0.004874 (rank : 96)
Query Neighborhood Hits	100	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q64701	Gene names	Rbl1
Domain Architecture
Description	Retinoblastoma-like protein 1 (107 kDa retinoblastoma-associated protein) (PRB1) (P107).

TITIN_HUMAN
θ value	6.88961 (rank : 98)	NC score	-0.006463 (rank : 105)
Query Neighborhood Hits	100	Target Neighborhood Hits	2923	Shared Neighborhood Hits	19
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

UB7I1_HUMAN
θ value	8.99809 (rank : 99)	NC score	0.005163 (rank : 95)
Query Neighborhood Hits	100	Target Neighborhood Hits	177	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NWF9, Q6Y691, Q75ML7, Q7Z2H7, Q7Z7C1, Q8NHW7, Q9NYT1	Gene names	UBCE7IP1, ZIN
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) (Triad domain-containing protein 3).

ZN438_HUMAN
θ value	8.99809 (rank : 100)	NC score	-0.004032 (rank : 104)
Query Neighborhood Hits	100	Target Neighborhood Hits	906	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z4V0, Q5T426, Q658Q4, Q6ZN65	Gene names	ZNF438
Domain Architecture	No domain graphic available
Description	Zinc finger protein 438.

CN092_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.216758 (rank : 78)
Query Neighborhood Hits	100	Target Neighborhood Hits	143	Shared Neighborhood Hits	61
SwissProt Accessions	O94842	Gene names	C14orf92, KIAA0737
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

CN092_MOUSE
θ value	θ > 10 (rank : 102)	NC score	0.210214 (rank : 79)
Query Neighborhood Hits	100	Target Neighborhood Hits	206	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BU11, Q80UI2, Q99PN9, Q9CS16	Gene names
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

GCX1_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.156778 (rank : 82)
Query Neighborhood Hits	100	Target Neighborhood Hits	132	Shared Neighborhood Hits	51
SwissProt Accessions	Q96NM4, Q5TE33, Q5TE34, Q5TE35, Q96IC9, Q9BQN5	Gene names	GCX1, C20orf100
Domain Architecture
Description	Granulosa cell HMG box protein 1 (GCX-1).

TOX_HUMAN
θ value	θ > 10 (rank : 104)	NC score	0.190236 (rank : 81)
Query Neighborhood Hits	100	Target Neighborhood Hits	106	Shared Neighborhood Hits	49
SwissProt Accessions	O94900, Q96AV5	Gene names	TOX, KIAA0808
Domain Architecture	No domain graphic available
Description	Thymus high mobility group box protein TOX.

TOX_MOUSE
θ value	θ > 10 (rank : 105)	NC score	0.191430 (rank : 80)
Query Neighborhood Hits	100	Target Neighborhood Hits	95	Shared Neighborhood Hits	49
SwissProt Accessions	Q66JW3, Q8BKH9, Q8BYQ5, Q8R4H0	Gene names	Tox
Domain Architecture	No domain graphic available
Description	Thymus high mobility group box protein TOX.

Hits sorted by NC score

SOX8_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	100	Target Neighborhood Hits	100	Shared Neighborhood Hits	100
SwissProt Accessions	P57073, Q9NZW2	Gene names	SOX8
Domain Architecture
Description	Transcription factor SOX-8.

SOX8_MOUSE
NC score	0.997400 (rank : 2)	θ value	2.26584e-152 (rank : 2)
Query Neighborhood Hits	100	Target Neighborhood Hits	96	Shared Neighborhood Hits	81
SwissProt Accessions	Q04886	Gene names	Sox8, Sox-8
Domain Architecture
Description	Transcription factor SOX-8.

SOX10_HUMAN
NC score	0.982453 (rank : 3)	θ value	1.59853e-89 (rank : 5)
Query Neighborhood Hits	100	Target Neighborhood Hits	122	Shared Neighborhood Hits	74
SwissProt Accessions	P56693	Gene names	SOX10
Domain Architecture
Description	Transcription factor SOX-10.

SOX10_MOUSE
NC score	0.982438 (rank : 4)	θ value	4.81303e-86 (rank : 6)
Query Neighborhood Hits	100	Target Neighborhood Hits	110	Shared Neighborhood Hits	74
SwissProt Accessions	Q04888, O08518, O09141, O54856, P70416	Gene names	Sox10, Sox-10, Sox21
Domain Architecture
Description	Transcription factor SOX-10 (SOX-21) (Transcription factor SOX-M).

SOX9_MOUSE
NC score	0.978037 (rank : 5)	θ value	2.54619e-95 (rank : 3)
Query Neighborhood Hits	100	Target Neighborhood Hits	188	Shared Neighborhood Hits	78
SwissProt Accessions	Q04887, Q8C7L2, Q91ZK2, Q99KQ0	Gene names	Sox9, Sox-9
Domain Architecture
Description	Transcription factor SOX-9.

SOX9_HUMAN
NC score	0.976107 (rank : 6)	θ value	1.65039e-94 (rank : 4)
Query Neighborhood Hits	100	Target Neighborhood Hits	210	Shared Neighborhood Hits	79
SwissProt Accessions	P48436	Gene names	SOX9
Domain Architecture
Description	Transcription factor SOX-9.

SOX12_MOUSE
NC score	0.958092 (rank : 7)	θ value	3.87602e-27 (rank : 19)
Query Neighborhood Hits	100	Target Neighborhood Hits	98	Shared Neighborhood Hits	76
SwissProt Accessions	Q04890, P70417, Q6NXL2	Gene names	Sox12, Sox-12
Domain Architecture	No domain graphic available
Description	SOX-12 protein.

SOX12_HUMAN
NC score	0.955368 (rank : 8)	θ value	2.96777e-27 (rank : 15)
Query Neighborhood Hits	100	Target Neighborhood Hits	111	Shared Neighborhood Hits	76
SwissProt Accessions	O15370, Q9NUD4	Gene names	SOX12, SOX22
Domain Architecture
Description	SOX-12 protein (SOX-22 protein).

SOX11_HUMAN
NC score	0.943293 (rank : 9)	θ value	1.12775e-26 (rank : 24)
Query Neighborhood Hits	100	Target Neighborhood Hits	89	Shared Neighborhood Hits	77
SwissProt Accessions	P35716	Gene names	SOX11
Domain Architecture
Description	Transcription factor SOX-11.

SOX21_MOUSE
NC score	0.942535 (rank : 10)	θ value	7.80994e-28 (rank : 13)
Query Neighborhood Hits	100	Target Neighborhood Hits	90	Shared Neighborhood Hits	77
SwissProt Accessions	Q811W0, Q8VH35	Gene names	Sox21
Domain Architecture	No domain graphic available
Description	Transcription factor SOX-21.

SOX21_HUMAN
NC score	0.942512 (rank : 11)	θ value	7.80994e-28 (rank : 12)
Query Neighborhood Hits	100	Target Neighborhood Hits	89	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y651, P35715, Q15504	Gene names	SOX21, SOX25, SOXA
Domain Architecture
Description	Transcription factor SOX-21 (SOX-A).

SOX15_MOUSE
NC score	0.940856 (rank : 12)	θ value	5.59698e-26 (rank : 29)
Query Neighborhood Hits	100	Target Neighborhood Hits	100	Shared Neighborhood Hits	78
SwissProt Accessions	P43267, O70204, P70418, Q62246, Q91V00, Q91V43, Q920T1, Q9JLG2	Gene names	Sox15, Sox-15
Domain Architecture
Description	SOX-15 protein.

SOX4_HUMAN
NC score	0.940738 (rank : 13)	θ value	2.05525e-28 (rank : 11)
Query Neighborhood Hits	100	Target Neighborhood Hits	111	Shared Neighborhood Hits	77
SwissProt Accessions	Q06945	Gene names	SOX4
Domain Architecture
Description	Transcription factor SOX-4.

SOX11_MOUSE
NC score	0.940485 (rank : 14)	θ value	1.92365e-26 (rank : 26)
Query Neighborhood Hits	100	Target Neighborhood Hits	96	Shared Neighborhood Hits	78
SwissProt Accessions	Q7M6Y2, O35178, O89036, Q04889, Q80XF0	Gene names	Sox11, Sox-11
Domain Architecture	No domain graphic available
Description	Transcription factor SOX-11.

SOX4_MOUSE
NC score	0.938365 (rank : 15)	θ value	1.33217e-27 (rank : 14)
Query Neighborhood Hits	100	Target Neighborhood Hits	108	Shared Neighborhood Hits	77
SwissProt Accessions	Q06831	Gene names	Sox4, Sox-4
Domain Architecture
Description	Transcription factor SOX-4.

SOX15_HUMAN
NC score	0.937498 (rank : 16)	θ value	8.63488e-27 (rank : 23)
Query Neighborhood Hits	100	Target Neighborhood Hits	134	Shared Neighborhood Hits	77
SwissProt Accessions	O60248, P35717, Q9Y6W7	Gene names	SOX15, SOX12, SOX20, SOX26, SOX27
Domain Architecture
Description	SOX-15 protein (SOX-20 protein) (SOX-12 protein).

SOX18_MOUSE
NC score	0.935938 (rank : 17)	θ value	3.87602e-27 (rank : 20)
Query Neighborhood Hits	100	Target Neighborhood Hits	105	Shared Neighborhood Hits	77
SwissProt Accessions	P43680, Q9EQ73	Gene names	Sox18, Sox-18
Domain Architecture
Description	Transcription factor SOX-18.

SOX18_HUMAN
NC score	0.935354 (rank : 18)	θ value	2.96777e-27 (rank : 18)
Query Neighborhood Hits	100	Target Neighborhood Hits	106	Shared Neighborhood Hits	79
SwissProt Accessions	P35713, Q9NPH8	Gene names	SOX18
Domain Architecture
Description	Transcription factor SOX-18.

SOX1_HUMAN
NC score	0.933185 (rank : 19)	θ value	4.14116e-29 (rank : 9)
Query Neighborhood Hits	100	Target Neighborhood Hits	90	Shared Neighborhood Hits	78
SwissProt Accessions	O00570	Gene names	SOX1
Domain Architecture
Description	SOX-1 protein.

SOX14_MOUSE
NC score	0.933155 (rank : 20)	θ value	2.96777e-27 (rank : 17)
Query Neighborhood Hits	100	Target Neighborhood Hits	100	Shared Neighborhood Hits	77
SwissProt Accessions	Q04892, Q9JLC9, Q9JLD0, Q9QXU4	Gene names	Sox14, Sox-14
Domain Architecture
Description	Transcription factor SOX-14.

SOX14_HUMAN
NC score	0.933028 (rank : 21)	θ value	2.96777e-27 (rank : 16)
Query Neighborhood Hits	100	Target Neighborhood Hits	102	Shared Neighborhood Hits	77
SwissProt Accessions	O95416, Q3KPH7	Gene names	SOX14, SOX28
Domain Architecture
Description	Transcription factor SOX-14.

SRY_HUMAN
NC score	0.932142 (rank : 22)	θ value	1.74391e-19 (rank : 38)
Query Neighborhood Hits	100	Target Neighborhood Hits	83	Shared Neighborhood Hits	77
SwissProt Accessions	Q05066	Gene names	SRY, TDF
Domain Architecture
Description	Sex-determining region Y protein (Testis-determining factor).

SOX1_MOUSE
NC score	0.931974 (rank : 23)	θ value	9.2256e-29 (rank : 10)
Query Neighborhood Hits	100	Target Neighborhood Hits	90	Shared Neighborhood Hits	77
SwissProt Accessions	P53783	Gene names	Sox1, Sox-1
Domain Architecture
Description	SOX-1 protein.

SOX17_HUMAN
NC score	0.930526 (rank : 24)	θ value	8.3442e-30 (rank : 8)
Query Neighborhood Hits	100	Target Neighborhood Hits	108	Shared Neighborhood Hits	76
SwissProt Accessions	Q9H6I2	Gene names	SOX17
Domain Architecture
Description	Transcription factor SOX-17.

SOX3_MOUSE
NC score	0.928568 (rank : 25)	θ value	1.12775e-26 (rank : 25)
Query Neighborhood Hits	100	Target Neighborhood Hits	101	Shared Neighborhood Hits	77
SwissProt Accessions	P53784	Gene names	Sox3, Sox-3
Domain Architecture
Description	Transcription factor SOX-3.

SOX2_HUMAN
NC score	0.926339 (rank : 26)	θ value	6.61148e-27 (rank : 21)
Query Neighborhood Hits	100	Target Neighborhood Hits	89	Shared Neighborhood Hits	77
SwissProt Accessions	P48431, Q14537	Gene names	SOX2
Domain Architecture
Description	Transcription factor SOX-2.

SOX2_MOUSE
NC score	0.926020 (rank : 27)	θ value	6.61148e-27 (rank : 22)
Query Neighborhood Hits	100	Target Neighborhood Hits	90	Shared Neighborhood Hits	77
SwissProt Accessions	P48432	Gene names	Sox2, Sox-2
Domain Architecture
Description	Transcription factor SOX-2.

SOX3_HUMAN
NC score	0.923992 (rank : 28)	θ value	1.62847e-25 (rank : 30)
Query Neighborhood Hits	100	Target Neighborhood Hits	109	Shared Neighborhood Hits	78
SwissProt Accessions	P41225, P35714, Q9NP49	Gene names	SOX3
Domain Architecture
Description	Transcription factor SOX-3.

SOX7_MOUSE
NC score	0.921081 (rank : 29)	θ value	4.28545e-26 (rank : 28)
Query Neighborhood Hits	100	Target Neighborhood Hits	105	Shared Neighborhood Hits	76
SwissProt Accessions	P40646, Q9R1T6	Gene names	Sox7, Sox-7
Domain Architecture
Description	Transcription factor SOX-7 (mSOX7).

SOX17_MOUSE
NC score	0.919133 (rank : 30)	θ value	4.89182e-30 (rank : 7)
Query Neighborhood Hits	100	Target Neighborhood Hits	223	Shared Neighborhood Hits	79
SwissProt Accessions	Q61473, Q61472, Q62248	Gene names	Sox17, Sox-17
Domain Architecture
Description	Transcription factor SOX-17.

SRY_MOUSE
NC score	0.916945 (rank : 31)	θ value	1.6852e-22 (rank : 31)
Query Neighborhood Hits	100	Target Neighborhood Hits	139	Shared Neighborhood Hits	77
SwissProt Accessions	Q05738	Gene names	Sry, Tdf, Tdy
Domain Architecture
Description	Sex-determining region Y protein (Testis-determining factor).

SOX7_HUMAN
NC score	0.915241 (rank : 32)	θ value	3.28125e-26 (rank : 27)
Query Neighborhood Hits	100	Target Neighborhood Hits	140	Shared Neighborhood Hits	77
SwissProt Accessions	Q9BT81	Gene names	SOX7
Domain Architecture
Description	Transcription factor SOX-7.

SOX5_MOUSE
NC score	0.835551 (rank : 33)	θ value	9.24701e-21 (rank : 33)
Query Neighborhood Hits	100	Target Neighborhood Hits	196	Shared Neighborhood Hits	75
SwissProt Accessions	P35710, O88184, O89018	Gene names	Sox5, Sox-5
Domain Architecture
Description	Transcription factor SOX-5.

SOX5_HUMAN
NC score	0.833054 (rank : 34)	θ value	9.24701e-21 (rank : 32)
Query Neighborhood Hits	100	Target Neighborhood Hits	219	Shared Neighborhood Hits	77
SwissProt Accessions	P35711, Q86UK8, Q8J017, Q8J018, Q8J019, Q8J020, Q8N1D9, Q8N7E0, Q8TEA4	Gene names	SOX5
Domain Architecture
Description	Transcription factor SOX-5.

SOX6_HUMAN
NC score	0.815247 (rank : 35)	θ value	2.69047e-20 (rank : 34)
Query Neighborhood Hits	100	Target Neighborhood Hits	332	Shared Neighborhood Hits	78
SwissProt Accessions	P35712, Q9BXQ3, Q9BXQ4, Q9BXQ5, Q9H0I8	Gene names	SOX6
Domain Architecture
Description	Transcription factor SOX-6.

SOX6_MOUSE
NC score	0.814339 (rank : 36)	θ value	2.69047e-20 (rank : 35)
Query Neighborhood Hits	100	Target Neighborhood Hits	341	Shared Neighborhood Hits	79
SwissProt Accessions	P40645, Q62250, Q9QWS5	Gene names	Sox6, Sox-6
Domain Architecture
Description	Transcription factor SOX-6 (SOX-LZ).

SOX13_MOUSE
NC score	0.809369 (rank : 37)	θ value	7.82807e-20 (rank : 37)
Query Neighborhood Hits	100	Target Neighborhood Hits	495	Shared Neighborhood Hits	81
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

SOX30_MOUSE
NC score	0.806971 (rank : 38)	θ value	3.07829e-16 (rank : 40)
Query Neighborhood Hits	100	Target Neighborhood Hits	374	Shared Neighborhood Hits	79
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

SOX13_HUMAN
NC score	0.806516 (rank : 39)	θ value	7.82807e-20 (rank : 36)
Query Neighborhood Hits	100	Target Neighborhood Hits	464	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

SOX30_HUMAN
NC score	0.804763 (rank : 40)	θ value	3.07829e-16 (rank : 39)
Query Neighborhood Hits	100	Target Neighborhood Hits	305	Shared Neighborhood Hits	78
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

HBP1_MOUSE
NC score	0.676354 (rank : 41)	θ value	4.45536e-07 (rank : 51)
Query Neighborhood Hits	100	Target Neighborhood Hits	86	Shared Neighborhood Hits	76
SwissProt Accessions	Q8R316, Q3V0I4, Q8BUS3, Q8C199	Gene names	Hbp1
Domain Architecture	No domain graphic available
Description	HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1).

HBP1_HUMAN
NC score	0.676325 (rank : 42)	θ value	4.45536e-07 (rank : 50)
Query Neighborhood Hits	100	Target Neighborhood Hits	89	Shared Neighborhood Hits	75
SwissProt Accessions	O60381, Q8TBM1, Q8TE93, Q96AJ2	Gene names	HBP1
Domain Architecture	No domain graphic available
Description	HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1).

CIC_MOUSE
NC score	0.651190 (rank : 43)	θ value	3.89403e-11 (rank : 41)
Query Neighborhood Hits	100	Target Neighborhood Hits	742	Shared Neighborhood Hits	79
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

BBX_HUMAN
NC score	0.643229 (rank : 44)	θ value	1.29631e-06 (rank : 57)
Query Neighborhood Hits	100	Target Neighborhood Hits	167	Shared Neighborhood Hits	75
SwissProt Accessions	Q8WY36, Q2TAJ1, Q7L3J8, Q7LBY8, Q8NDB0, Q8WY35, Q9H0J6	Gene names	BBX, HBP2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

BBX_MOUSE
NC score	0.633359 (rank : 45)	θ value	2.88788e-06 (rank : 59)
Query Neighborhood Hits	100	Target Neighborhood Hits	152	Shared Neighborhood Hits	74
SwissProt Accessions	Q8VBW5, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VI48, Q8VI49, Q8VI50, Q9CS94	Gene names	Bbx, Hbp2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

TCF7_HUMAN
NC score	0.633112 (rank : 46)	θ value	3.77169e-06 (rank : 60)
Query Neighborhood Hits	100	Target Neighborhood Hits	186	Shared Neighborhood Hits	70
SwissProt Accessions	P36402, Q9UKI4	Gene names	TCF7, TCF1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

HMGB3_HUMAN
NC score	0.630936 (rank : 47)	θ value	1.80886e-08 (rank : 46)
Query Neighborhood Hits	100	Target Neighborhood Hits	86	Shared Neighborhood Hits	69
SwissProt Accessions	O15347, O95556, Q6NS40	Gene names	HMGB3, HMG2A, HMG4
Domain Architecture
Description	High mobility group protein B3 (High mobility group protein 4) (HMG-4) (High mobility group protein 2a) (HMG-2a).

HMGB3_MOUSE
NC score	0.621930 (rank : 48)	θ value	1.38499e-08 (rank : 43)
Query Neighborhood Hits	100	Target Neighborhood Hits	88	Shared Neighborhood Hits	69
SwissProt Accessions	O54879	Gene names	Hmgb3, Hmg2a, Hmg4
Domain Architecture
Description	High mobility group protein B3 (High mobility group protein 4) (HMG-4) (High mobility group protein 2a) (HMG-2a).

CIC_HUMAN
NC score	0.611579 (rank : 49)	θ value	1.9326e-10 (rank : 42)
Query Neighborhood Hits	100	Target Neighborhood Hits	992	Shared Neighborhood Hits	80
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

TCF7_MOUSE
NC score	0.598092 (rank : 50)	θ value	2.61198e-07 (rank : 49)
Query Neighborhood Hits	100	Target Neighborhood Hits	277	Shared Neighborhood Hits	69
SwissProt Accessions	Q00417	Gene names	Tcf7, Tcf-1, Tcf1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

TF7L2_MOUSE
NC score	0.593206 (rank : 51)	θ value	1.38499e-08 (rank : 45)
Query Neighborhood Hits	100	Target Neighborhood Hits	95	Shared Neighborhood Hits	65
SwissProt Accessions	Q924A0, O70574, Q91XP2, Q91XP3, Q91XP4, Q924A1, Q9Z0V3, Q9Z0V4	Gene names	Tcf7l2, Tcf4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (mTCF-4).

TF7L2_HUMAN
NC score	0.589894 (rank : 52)	θ value	1.38499e-08 (rank : 44)
Query Neighborhood Hits	100	Target Neighborhood Hits	119	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NQB0, O00185, Q9NQB1, Q9NQB2, Q9NQB3, Q9NQB4, Q9NQB5, Q9NQB6, Q9NQB7, Q9ULC2	Gene names	TCF7L2, TCF4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (hTCF-4).

SSRP1_MOUSE
NC score	0.589139 (rank : 53)	θ value	1.53129e-07 (rank : 47)
Query Neighborhood Hits	100	Target Neighborhood Hits	193	Shared Neighborhood Hits	78
SwissProt Accessions	Q08943, Q3U9Z2, Q3UJ75, Q4V9U4, Q8CGA6	Gene names	Ssrp1
Domain Architecture
Description	FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (Structure-specific recognition protein 1) (Recombination signal sequence recognition protein 1) (T160).

SSRP1_HUMAN
NC score	0.581913 (rank : 54)	θ value	2.61198e-07 (rank : 48)
Query Neighborhood Hits	100	Target Neighborhood Hits	187	Shared Neighborhood Hits	78
SwissProt Accessions	Q08945, Q5BJG8	Gene names	SSRP1, FACT80
Domain Architecture
Description	FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (FACT 80 kDa subunit) (FACTp80) (Chromatin- specific transcription elongation factor 80 kDa subunit) (Structure- specific recognition protein 1) (hSSRP1) (Recombination signal sequence recognition protein 1) (T160).

LEF1_HUMAN
NC score	0.581349 (rank : 55)	θ value	9.92553e-07 (rank : 56)
Query Neighborhood Hits	100	Target Neighborhood Hits	150	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UJU2, Q9HAZ0	Gene names	LEF1
Domain Architecture
Description	Lymphoid enhancer-binding factor 1 (LEF-1) (T cell-specific transcription factor 1-alpha) (TCF1-alpha).

LEF1_MOUSE
NC score	0.580185 (rank : 56)	θ value	7.59969e-07 (rank : 53)
Query Neighborhood Hits	100	Target Neighborhood Hits	161	Shared Neighborhood Hits	72
SwissProt Accessions	P27782	Gene names	Lef1, Lef-1
Domain Architecture
Description	Lymphoid enhancer-binding factor 1 (LEF-1).

TF7L1_MOUSE
NC score	0.576254 (rank : 57)	θ value	7.59969e-07 (rank : 54)
Query Neighborhood Hits	100	Target Neighborhood Hits	131	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Z1J1, O70450, O70573	Gene names	Tcf7l1, Tcf3
Domain Architecture
Description	Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF-3) (mTCF-3).

TF7L1_HUMAN
NC score	0.573699 (rank : 58)	θ value	5.81887e-07 (rank : 52)
Query Neighborhood Hits	100	Target Neighborhood Hits	129	Shared Neighborhood Hits	68
SwissProt Accessions	Q9HCS4, Q53R97, Q6PD70, Q9NP00	Gene names	TCF7L1, TCF3
Domain Architecture
Description	Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF- 3).

HMGB2_HUMAN
NC score	0.572916 (rank : 59)	θ value	9.92553e-07 (rank : 55)
Query Neighborhood Hits	100	Target Neighborhood Hits	114	Shared Neighborhood Hits	78
SwissProt Accessions	P26583	Gene names	HMGB2, HMG2
Domain Architecture
Description	High mobility group protein B2 (High mobility group protein 2) (HMG- 2).

HMGB2_MOUSE
NC score	0.560980 (rank : 60)	θ value	2.21117e-06 (rank : 58)
Query Neighborhood Hits	100	Target Neighborhood Hits	111	Shared Neighborhood Hits	76
SwissProt Accessions	P30681, Q3UXT1, Q9EQD5	Gene names	Hmgb2, Hmg2
Domain Architecture
Description	High mobility group protein B2 (High mobility group protein 2) (HMG- 2).

HM20B_HUMAN
NC score	0.548427 (rank : 61)	θ value	9.29e-05 (rank : 66)
Query Neighborhood Hits	100	Target Neighborhood Hits	126	Shared Neighborhood Hits	74
SwissProt Accessions	Q9P0W2, Q6IBP8, Q8NBD5, Q9HD21, Q9Y491, Q9Y4A2	Gene names	HMG20B, BRAF35, HMGX2, SMARCE1R
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (HMG domain protein HMG20B) (Structural DNA-binding protein BRAF35) (BRCA2- associated factor 35) (Sox-like transcriptional factor).

HMGB1_MOUSE
NC score	0.532878 (rank : 62)	θ value	1.09739e-05 (rank : 63)
Query Neighborhood Hits	100	Target Neighborhood Hits	123	Shared Neighborhood Hits	75
SwissProt Accessions	P63158, P07155, P27109, P27428	Gene names	Hmgb1, Hmg-1, Hmg1
Domain Architecture	No domain graphic available
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

HMGB1_HUMAN
NC score	0.532764 (rank : 63)	θ value	1.09739e-05 (rank : 62)
Query Neighborhood Hits	100	Target Neighborhood Hits	126	Shared Neighborhood Hits	75
SwissProt Accessions	P09429, Q6IBE1	Gene names	HMGB1, HMG1
Domain Architecture
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

HM20B_MOUSE
NC score	0.527014 (rank : 64)	θ value	0.00102713 (rank : 67)
Query Neighborhood Hits	100	Target Neighborhood Hits	122	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Z104, Q9NSF7, Q9NSF8	Gene names	Hmg20b, Braf35, Hmgx2, Smarce1r
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (HMG domain protein HMG20B) (Structural DNA-binding protein BRAF35) (BRCA2- associated factor 35).

HMG1X_HUMAN
NC score	0.499482 (rank : 65)	θ value	2.44474e-05 (rank : 65)
Query Neighborhood Hits	100	Target Neighborhood Hits	97	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UGV6	Gene names	HMG1L10
Domain Architecture
Description	High mobility group protein 1-like 10 (HMG-1L10).

UBF1_HUMAN
NC score	0.485125 (rank : 66)	θ value	8.40245e-06 (rank : 61)
Query Neighborhood Hits	100	Target Neighborhood Hits	415	Shared Neighborhood Hits	78
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

UBF1_MOUSE
NC score	0.477161 (rank : 67)	θ value	1.87187e-05 (rank : 64)
Query Neighborhood Hits	100	Target Neighborhood Hits	419	Shared Neighborhood Hits	77
SwissProt Accessions	P25976	Gene names	Ubtf, Tcfubf, Ubf-1, Ubf1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1).

HM2L1_HUMAN
NC score	0.458551 (rank : 68)	θ value	0.00665767 (rank : 69)
Query Neighborhood Hits	100	Target Neighborhood Hits	130	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UGU5, O75672, O75673, Q9UMT5	Gene names	HMG2L1, HMGBCG
Domain Architecture
Description	High mobility group protein 2-like 1 (Protein HMGBCG).

HM20A_HUMAN
NC score	0.449867 (rank : 69)	θ value	0.00869519 (rank : 70)
Query Neighborhood Hits	100	Target Neighborhood Hits	343	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NP66, Q53G31, Q9NSF6	Gene names	HMG20A, HMGX1
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein HMGX1).

HM20A_MOUSE
NC score	0.447900 (rank : 70)	θ value	0.00869519 (rank : 71)
Query Neighborhood Hits	100	Target Neighborhood Hits	348	Shared Neighborhood Hits	75
SwissProt Accessions	Q9DC33, Q3LSF9, Q6NV87, Q8BSK1, Q8C3C1, Q8CAA0, Q9CYG2	Gene names	Hmg20a, Ibraf
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (iBRAF) (Inhibitor of BRAF35) (HMG domain protein HMGX1).

TFAM_MOUSE
NC score	0.350347 (rank : 71)	θ value	0.365318 (rank : 77)
Query Neighborhood Hits	100	Target Neighborhood Hits	93	Shared Neighborhood Hits	74
SwissProt Accessions	P40630, P97894, P97906, Q543I8, Q9DBM9	Gene names	Tfam, Hmgts
Domain Architecture
Description	Transcription factor A, mitochondrial precursor (mtTFA) (Testis- specific high mobility group protein) (TS-HMG).

SMCE1_HUMAN
NC score	0.334707 (rank : 72)	θ value	0.0736092 (rank : 74)
Query Neighborhood Hits	100	Target Neighborhood Hits	272	Shared Neighborhood Hits	64
SwissProt Accessions	Q969G3, O43539	Gene names	SMARCE1, BAF57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 (BRG1-associated factor 57).

SMCE1_MOUSE
NC score	0.314604 (rank : 73)	θ value	0.0736092 (rank : 75)
Query Neighborhood Hits	100	Target Neighborhood Hits	409	Shared Neighborhood Hits	64
SwissProt Accessions	O54941, Q8BPD9	Gene names	Smarce1, Baf57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator chromatin subfamily E member 1 (BRG1-associated factor 57).

SP100_HUMAN
NC score	0.306579 (rank : 74)	θ value	0.00390308 (rank : 68)
Query Neighborhood Hits	100	Target Neighborhood Hits	117	Shared Neighborhood Hits	63
SwissProt Accessions	P23497, O75450, Q13343, Q96F70, Q96T24, Q96T95, Q9NP33, Q9UE32	Gene names	SP100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein) (Lysp100b).

TFAM_HUMAN
NC score	0.291295 (rank : 75)	θ value	5.27518 (rank : 94)
Query Neighborhood Hits	100	Target Neighborhood Hits	156	Shared Neighborhood Hits	58
SwissProt Accessions	Q00059	Gene names	TFAM, TCF6L2
Domain Architecture
Description	Transcription factor A, mitochondrial precursor (mtTFA) (Mitochondrial transcription factor 1) (MtTF1) (Transcription factor 6-like 2).

PB1_HUMAN
NC score	0.283764 (rank : 76)	θ value	0.00869519 (rank : 72)
Query Neighborhood Hits	100	Target Neighborhood Hits	261	Shared Neighborhood Hits	77
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

PMS1_HUMAN
NC score	0.261380 (rank : 77)	θ value	0.21417 (rank : 76)
Query Neighborhood Hits	100	Target Neighborhood Hits	126	Shared Neighborhood Hits	65
SwissProt Accessions	P54277	Gene names	PMS1, PMSL1
Domain Architecture
Description	PMS1 protein homolog 1 (DNA mismatch repair protein PMS1).

CN092_HUMAN
NC score	0.216758 (rank : 78)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	100	Target Neighborhood Hits	143	Shared Neighborhood Hits	61
SwissProt Accessions	O94842	Gene names	C14orf92, KIAA0737
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

CN092_MOUSE
NC score	0.210214 (rank : 79)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	100	Target Neighborhood Hits	206	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BU11, Q80UI2, Q99PN9, Q9CS16	Gene names
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

TOX_MOUSE
NC score	0.191430 (rank : 80)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	100	Target Neighborhood Hits	95	Shared Neighborhood Hits	49
SwissProt Accessions	Q66JW3, Q8BKH9, Q8BYQ5, Q8R4H0	Gene names	Tox
Domain Architecture	No domain graphic available
Description	Thymus high mobility group box protein TOX.

TOX_HUMAN
NC score	0.190236 (rank : 81)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	100	Target Neighborhood Hits	106	Shared Neighborhood Hits	49
SwissProt Accessions	O94900, Q96AV5	Gene names	TOX, KIAA0808
Domain Architecture	No domain graphic available
Description	Thymus high mobility group box protein TOX.

GCX1_HUMAN
NC score	0.156778 (rank : 82)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	100	Target Neighborhood Hits	132	Shared Neighborhood Hits	51
SwissProt Accessions	Q96NM4, Q5TE33, Q5TE34, Q5TE35, Q96IC9, Q9BQN5	Gene names	GCX1, C20orf100
Domain Architecture
Description	Granulosa cell HMG box protein 1 (GCX-1).

EYA1_MOUSE
NC score	0.027916 (rank : 83)	θ value	0.0330416 (rank : 73)
Query Neighborhood Hits	100	Target Neighborhood Hits	108	Shared Neighborhood Hits	5
SwissProt Accessions	P97767, O08818	Gene names	Eya1
Domain Architecture
Description	Eyes absent homolog 1 (EC 3.1.3.48).

MB3L2_HUMAN
NC score	0.023600 (rank : 84)	θ value	4.03905 (rank : 90)
Query Neighborhood Hits	100	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NHZ7	Gene names	MBD3L2
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3-like 2 (MBD3-like 2).

BCL9_HUMAN
NC score	0.020024 (rank : 85)	θ value	3.0926 (rank : 85)
Query Neighborhood Hits	100	Target Neighborhood Hits	1008	Shared Neighborhood Hits	21
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

GCH1_HUMAN
NC score	0.019848 (rank : 86)	θ value	1.06291 (rank : 80)
Query Neighborhood Hits	100	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	P30793, Q9Y4I8	Gene names	GCH1, DYT5, GCH
Domain Architecture
Description	GTP cyclohydrolase I (EC 3.5.4.16) (GTP-CH-I).

LCP2_HUMAN
NC score	0.018781 (rank : 87)	θ value	1.38821 (rank : 83)
Query Neighborhood Hits	100	Target Neighborhood Hits	531	Shared Neighborhood Hits	12
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

MLL2_HUMAN
NC score	0.018543 (rank : 88)	θ value	5.27518 (rank : 93)
Query Neighborhood Hits	100	Target Neighborhood Hits	1788	Shared Neighborhood Hits	25
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

ECM1_HUMAN
NC score	0.016395 (rank : 89)	θ value	2.36792 (rank : 84)
Query Neighborhood Hits	100	Target Neighborhood Hits	182	Shared Neighborhood Hits	8
SwissProt Accessions	Q16610	Gene names	ECM1
Domain Architecture
Description	Extracellular matrix protein 1 precursor (Secretory component p85).

BORG1_HUMAN
NC score	0.011339 (rank : 90)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	100	Target Neighborhood Hits	67	Shared Neighborhood Hits	4
SwissProt Accessions	O14613, Q9UNS0	Gene names	CDC42EP2, BORG1, CEP2
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 2 (Binder of Rho GTPases 1).

CPT1C_MOUSE
NC score	0.009208 (rank : 91)	θ value	3.0926 (rank : 87)
Query Neighborhood Hits	100	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BGD5	Gene names	Cpt1c
Domain Architecture
Description	Carnitine O-palmitoyltransferase I, brain isoform (EC 2.3.1.21) (Carnitine palmitoyltransferase 1C) (CPT IC).

CPT1C_HUMAN
NC score	0.009074 (rank : 92)	θ value	3.0926 (rank : 86)
Query Neighborhood Hits	100	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TCG5, Q8N6Q9, Q8NDS6, Q8TE84	Gene names	CPT1C
Domain Architecture
Description	Carnitine O-palmitoyltransferase I, brain isoform (EC 2.3.1.21) (Carnitine palmitoyltransferase 1C) (CPT IC).

K0141_HUMAN
NC score	0.007810 (rank : 93)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	100	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q14154, Q969R4, Q96EU9	Gene names	KIAA0141
Domain Architecture
Description	Protein KIAA0141.

ZN516_MOUSE
NC score	0.006556 (rank : 94)	θ value	0.365318 (rank : 78)
Query Neighborhood Hits	100	Target Neighborhood Hits	1197	Shared Neighborhood Hits	17
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

UB7I1_HUMAN
NC score	0.005163 (rank : 95)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	100	Target Neighborhood Hits	177	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NWF9, Q6Y691, Q75ML7, Q7Z2H7, Q7Z7C1, Q8NHW7, Q9NYT1	Gene names	UBCE7IP1, ZIN
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) (Triad domain-containing protein 3).

RBL1_MOUSE
NC score	0.004874 (rank : 96)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	100	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q64701	Gene names	Rbl1
Domain Architecture
Description	Retinoblastoma-like protein 1 (107 kDa retinoblastoma-associated protein) (PRB1) (P107).

CAC1A_HUMAN
NC score	0.004218 (rank : 97)	θ value	1.38821 (rank : 82)
Query Neighborhood Hits	100	Target Neighborhood Hits	387	Shared Neighborhood Hits	7
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

ACES_HUMAN
NC score	0.003475 (rank : 98)	θ value	4.03905 (rank : 88)
Query Neighborhood Hits	100	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	P22303, Q16169, Q86TM9, Q9BXP7	Gene names	ACHE
Domain Architecture
Description	Acetylcholinesterase precursor (EC 3.1.1.7) (AChE).

KCNQ3_HUMAN
NC score	0.003062 (rank : 99)	θ value	5.27518 (rank : 92)
Query Neighborhood Hits	100	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

WNK2_HUMAN
NC score	0.002808 (rank : 100)	θ value	1.06291 (rank : 81)
Query Neighborhood Hits	100	Target Neighborhood Hits	1407	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

ZN516_HUMAN
NC score	0.001995 (rank : 101)	θ value	0.47712 (rank : 79)
Query Neighborhood Hits	100	Target Neighborhood Hits	854	Shared Neighborhood Hits	8
SwissProt Accessions	Q92618	Gene names	ZNF516, KIAA0222
Domain Architecture	No domain graphic available
Description	Zinc finger protein 516.

HMX3_MOUSE
NC score	-0.000250 (rank : 102)	θ value	4.03905 (rank : 89)
Query Neighborhood Hits	100	Target Neighborhood Hits	342	Shared Neighborhood Hits	3
SwissProt Accessions	P42581	Gene names	Hmx3, Nkx-5.1, Nkx5-1
Domain Architecture
Description	Homeobox protein HMX3 (Homeobox protein Nkx-5.1).

HXA1_MOUSE
NC score	-0.001645 (rank : 103)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	100	Target Neighborhood Hits	341	Shared Neighborhood Hits	3
SwissProt Accessions	P09022, P15463	Gene names	Hoxa1, Era-1, Hox-1.6, Hoxa-1
Domain Architecture
Description	Homeobox protein Hox-A1 (Hox-1.6) (Homeotic protein ERA-1-993) (Early retinoic acid 1) (Homeoboxless protein ERA-1-399).

ZN438_HUMAN
NC score	-0.004032 (rank : 104)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	100	Target Neighborhood Hits	906	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z4V0, Q5T426, Q658Q4, Q6ZN65	Gene names	ZNF438
Domain Architecture	No domain graphic available
Description	Zinc finger protein 438.

TITIN_HUMAN
NC score	-0.006463 (rank : 105)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	100	Target Neighborhood Hits	2923	Shared Neighborhood Hits	19
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).