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Network neighborhood for query Sequence : SENP6_HUMAN

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SENP6_HUMAN
SwissProt Accessions	Q9GZR1, O94891, Q8TBY4, Q9UJV5	Gene names	SENP6, KIAA0797, SSP1, SUSP1
Domain Architecture
Description	Sentrin-specific protease 6 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP6) (SUMO-1-specific protease 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SENP6_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	69	Target Neighborhood Hits	69	Shared Neighborhood Hits	69
SwissProt Accessions	Q9GZR1, O94891, Q8TBY4, Q9UJV5	Gene names	SENP6, KIAA0797, SSP1, SUSP1
Domain Architecture
Description	Sentrin-specific protease 6 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP6) (SUMO-1-specific protease 1).

SENP7_HUMAN
θ value	1.08223e-53 (rank : 2)	NC score	0.771824 (rank : 2)
Query Neighborhood Hits	69	Target Neighborhood Hits	97	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BQF6, Q96PS5, Q9C0F6, Q9HBT5	Gene names	SENP7, KIAA1707, SSP2, SUSP2
Domain Architecture
Description	Sentrin-specific protease 7 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP7) (SUMO-1-specific protease 2).

SENP2_MOUSE
θ value	3.18553e-13 (rank : 3)	NC score	0.556761 (rank : 3)
Query Neighborhood Hits	69	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	Q91ZX6, Q544T8, Q9D4Z0	Gene names	Senp2, Smt3ip2
Domain Architecture
Description	Sentrin-specific protease 2 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP2) (SUMO-1/Smt3-specific isopeptidase 2) (Smt3ip2) (Axam2).

SENP1_HUMAN
θ value	3.52202e-12 (rank : 4)	NC score	0.553209 (rank : 4)
Query Neighborhood Hits	69	Target Neighborhood Hits	38	Shared Neighborhood Hits	11
SwissProt Accessions	Q9P0U3, Q86XC8	Gene names	SENP1
Domain Architecture
Description	Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1).

SENP1_MOUSE
θ value	7.84624e-12 (rank : 5)	NC score	0.549693 (rank : 5)
Query Neighborhood Hits	69	Target Neighborhood Hits	40	Shared Neighborhood Hits	13
SwissProt Accessions	P59110	Gene names	Senp1
Domain Architecture
Description	Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1).

SENP2_HUMAN
θ value	1.33837e-11 (rank : 6)	NC score	0.547410 (rank : 6)
Query Neighborhood Hits	69	Target Neighborhood Hits	19	Shared Neighborhood Hits	9
SwissProt Accessions	Q9HC62, Q96SR2, Q9P2L5	Gene names	SENP2, KIAA1331
Domain Architecture
Description	Sentrin-specific protease 2 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP2) (SMT3-specific isopeptidase 2) (Smt3ip2) (Axam2).

SENP3_HUMAN
θ value	2.61198e-07 (rank : 7)	NC score	0.481334 (rank : 8)
Query Neighborhood Hits	69	Target Neighborhood Hits	38	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H4L4, Q96PS4, Q9Y3W9	Gene names	SENP3, SSP3, SUSP3
Domain Architecture
Description	Sentrin-specific protease 3 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP3) (SUMO-1-specific protease 3).

SENP3_MOUSE
θ value	2.61198e-07 (rank : 8)	NC score	0.479389 (rank : 9)
Query Neighborhood Hits	69	Target Neighborhood Hits	44	Shared Neighborhood Hits	11
SwissProt Accessions	Q9EP97	Gene names	Senp3, Smt3ip, Smt3ip1
Domain Architecture
Description	Sentrin-specific protease 3 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP3) (SUMO-1-specific protease 3) (Smt3-specific isopeptidase 1) (Smt3ip1).

SENP5_HUMAN
θ value	3.41135e-07 (rank : 9)	NC score	0.489656 (rank : 7)
Query Neighborhood Hits	69	Target Neighborhood Hits	37	Shared Neighborhood Hits	12
SwissProt Accessions	Q96HI0, Q96SA5	Gene names	SENP5
Domain Architecture
Description	Sentrin-specific protease 5 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP5).

IF2P_HUMAN
θ value	0.0736092 (rank : 10)	NC score	0.047204 (rank : 20)
Query Neighborhood Hits	69	Target Neighborhood Hits	889	Shared Neighborhood Hits	16
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

MAP2_HUMAN
θ value	0.0961366 (rank : 11)	NC score	0.056885 (rank : 16)
Query Neighborhood Hits	69	Target Neighborhood Hits	348	Shared Neighborhood Hits	10
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

DDX23_HUMAN
θ value	0.279714 (rank : 12)	NC score	0.018047 (rank : 44)
Query Neighborhood Hits	69	Target Neighborhood Hits	486	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

SENP8_HUMAN
θ value	0.279714 (rank : 13)	NC score	0.152415 (rank : 10)
Query Neighborhood Hits	69	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	Q96LD8, Q96QA4	Gene names	SENP8, DEN1, NEDP1, PRSC2
Domain Architecture
Description	Sentrin-specific protease 8 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP8) (Protease, cysteine 2) (NEDD8-specific protease 1) (Deneddylase-1).

NCOR1_HUMAN
θ value	0.365318 (rank : 14)	NC score	0.039641 (rank : 26)
Query Neighborhood Hits	69	Target Neighborhood Hits	577	Shared Neighborhood Hits	13
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

CCD22_MOUSE
θ value	0.47712 (rank : 15)	NC score	0.058947 (rank : 15)
Query Neighborhood Hits	69	Target Neighborhood Hits	268	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JIG7, Q8BYH4	Gene names	Ccdc22, DXImx40e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 22.

VPS72_HUMAN
θ value	0.47712 (rank : 16)	NC score	0.077842 (rank : 13)
Query Neighborhood Hits	69	Target Neighborhood Hits	274	Shared Neighborhood Hits	11
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

VPS72_MOUSE
θ value	0.47712 (rank : 17)	NC score	0.078308 (rank : 12)
Query Neighborhood Hits	69	Target Neighborhood Hits	286	Shared Neighborhood Hits	12
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

PHAR2_HUMAN
θ value	0.62314 (rank : 18)	NC score	0.046083 (rank : 23)
Query Neighborhood Hits	69	Target Neighborhood Hits	208	Shared Neighborhood Hits	6
SwissProt Accessions	O75167, Q68DM2	Gene names	PHACTR2, C6orf56, KIAA0680
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 2.

AP3B2_MOUSE
θ value	0.813845 (rank : 19)	NC score	0.034164 (rank : 29)
Query Neighborhood Hits	69	Target Neighborhood Hits	246	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JME5, Q6QR53, Q8R1E5	Gene names	Ap3b2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain).

MEPE_HUMAN
θ value	0.813845 (rank : 20)	NC score	0.064754 (rank : 14)
Query Neighborhood Hits	69	Target Neighborhood Hits	105	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NQ76	Gene names	MEPE
Domain Architecture
Description	Matrix extracellular phosphoglycoprotein precursor (Osteoblast/osteocyte factor 45) (OF45).

BPA1_MOUSE
θ value	1.38821 (rank : 21)	NC score	0.014253 (rank : 49)
Query Neighborhood Hits	69	Target Neighborhood Hits	1477	Shared Neighborhood Hits	21
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CCD22_HUMAN
θ value	1.38821 (rank : 22)	NC score	0.055209 (rank : 17)
Query Neighborhood Hits	69	Target Neighborhood Hits	242	Shared Neighborhood Hits	6
SwissProt Accessions	O60826	Gene names	CCDC22, CXorf37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 22.

CD014_HUMAN
θ value	1.38821 (rank : 23)	NC score	0.041779 (rank : 24)
Query Neighborhood Hits	69	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NC60, Q8N7L6, Q9BSQ9	Gene names	C4orf14
Domain Architecture	No domain graphic available
Description	Protein C4orf14.

AR13B_HUMAN
θ value	1.81305 (rank : 24)	NC score	0.020891 (rank : 42)
Query Neighborhood Hits	69	Target Neighborhood Hits	528	Shared Neighborhood Hits	14
SwissProt Accessions	Q3SXY8, Q504W8	Gene names	ARL13B, ARL2L1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 2-like 1) (ARL2-like protein 1).

CCNB3_MOUSE
θ value	1.81305 (rank : 25)	NC score	0.028124 (rank : 35)
Query Neighborhood Hits	69	Target Neighborhood Hits	211	Shared Neighborhood Hits	9
SwissProt Accessions	Q810T2, Q810T3, Q8VDC8	Gene names	Ccnb3, Cycb3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

PHF14_HUMAN
θ value	1.81305 (rank : 26)	NC score	0.031723 (rank : 31)
Query Neighborhood Hits	69	Target Neighborhood Hits	447	Shared Neighborhood Hits	9
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

AP2B_HUMAN
θ value	2.36792 (rank : 27)	NC score	0.049069 (rank : 19)
Query Neighborhood Hits	69	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q92481, Q5JYX6, Q9NQ63, Q9NU99, Q9UJI7, Q9Y214, Q9Y3K3	Gene names	TFAP2B
Domain Architecture
Description	Transcription factor AP-2 beta (AP2-beta) (Activating enhancer-binding protein 2 beta).

AP2B_MOUSE
θ value	2.36792 (rank : 28)	NC score	0.049070 (rank : 18)
Query Neighborhood Hits	69	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q61313	Gene names	Tfap2b, Tcfap2b
Domain Architecture
Description	Transcription factor AP-2 beta (AP2-beta) (Activating enhancer-binding protein 2 beta).

DPOLZ_HUMAN
θ value	2.36792 (rank : 29)	NC score	0.038915 (rank : 27)
Query Neighborhood Hits	69	Target Neighborhood Hits	200	Shared Neighborhood Hits	8
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

DPOLZ_MOUSE
θ value	2.36792 (rank : 30)	NC score	0.039699 (rank : 25)
Query Neighborhood Hits	69	Target Neighborhood Hits	169	Shared Neighborhood Hits	6
SwissProt Accessions	Q61493, Q9JMD6, Q9QWX6	Gene names	Rev3l, Polz, Sez4
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Seizure-related protein 4).

NFM_HUMAN
θ value	2.36792 (rank : 31)	NC score	0.013247 (rank : 51)
Query Neighborhood Hits	69	Target Neighborhood Hits	1328	Shared Neighborhood Hits	23
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

NFM_MOUSE
θ value	2.36792 (rank : 32)	NC score	0.014411 (rank : 48)
Query Neighborhood Hits	69	Target Neighborhood Hits	1159	Shared Neighborhood Hits	20
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

AMRP_HUMAN
θ value	3.0926 (rank : 33)	NC score	0.031666 (rank : 32)
Query Neighborhood Hits	69	Target Neighborhood Hits	126	Shared Neighborhood Hits	4
SwissProt Accessions	P30533	Gene names	LRPAP1, A2MRAP
Domain Architecture
Description	Alpha-2-macroglobulin receptor-associated protein precursor (Alpha-2- MRAP) (Low density lipoprotein receptor-related protein-associated protein 1) (RAP).

AP2A_HUMAN
θ value	3.0926 (rank : 34)	NC score	0.046898 (rank : 22)
Query Neighborhood Hits	69	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	P05549, Q13777	Gene names	TFAP2A, AP2TF, TFAP2
Domain Architecture
Description	Transcription factor AP-2 alpha (AP2-alpha) (Activating enhancer- binding protein 2 alpha) (AP-2 transcription factor) (Activator protein 2) (AP-2).

AP2A_MOUSE
θ value	3.0926 (rank : 35)	NC score	0.046947 (rank : 21)
Query Neighborhood Hits	69	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	P34056, Q60740, Q60741, Q60742, Q60743, Q62067, Q62068, Q62069, Q91VX0, Q9CRY4	Gene names	Tfap2a, Ap2tf, Tcfap2a
Domain Architecture
Description	Transcription factor AP-2 alpha (AP2-alpha) (Activating enhancer- binding protein 2 alpha) (Activator protein 2) (AP-2).

FA50A_HUMAN
θ value	3.0926 (rank : 36)	NC score	0.029918 (rank : 34)
Query Neighborhood Hits	69	Target Neighborhood Hits	264	Shared Neighborhood Hits	8
SwissProt Accessions	Q14320, Q5HY37	Gene names	FAM50A, DXS9928E, HXC26, XAP5
Domain Architecture
Description	Protein FAM50A (Protein XAP-5) (Protein HXC-26).

MYH14_MOUSE
θ value	3.0926 (rank : 37)	NC score	0.008618 (rank : 59)
Query Neighborhood Hits	69	Target Neighborhood Hits	1225	Shared Neighborhood Hits	12
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

SENP8_MOUSE
θ value	3.0926 (rank : 38)	NC score	0.127520 (rank : 11)
Query Neighborhood Hits	69	Target Neighborhood Hits	9	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D2Z4, Q543P0	Gene names	Senp8, Den1, Nedp1
Domain Architecture
Description	Sentrin-specific protease 8 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP8) (NEDD8-specific protease 1) (Deneddylase-1).

BMP5_HUMAN
θ value	4.03905 (rank : 39)	NC score	0.009526 (rank : 58)
Query Neighborhood Hits	69	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	P22003, Q9H547, Q9NTM5	Gene names	BMP5
Domain Architecture
Description	Bone morphogenetic protein 5 precursor (BMP-5).

FA50A_MOUSE
θ value	4.03905 (rank : 40)	NC score	0.027231 (rank : 36)
Query Neighborhood Hits	69	Target Neighborhood Hits	293	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WV03, Q9D866	Gene names	Fam50a, D0HXS9928E, Xap5
Domain Architecture
Description	Protein FAM50A (XAP-5 protein).

PHF14_MOUSE
θ value	4.03905 (rank : 41)	NC score	0.025415 (rank : 38)
Query Neighborhood Hits	69	Target Neighborhood Hits	342	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

ADA30_HUMAN
θ value	5.27518 (rank : 42)	NC score	0.008518 (rank : 60)
Query Neighborhood Hits	69	Target Neighborhood Hits	391	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

CBX2_MOUSE
θ value	5.27518 (rank : 43)	NC score	0.018697 (rank : 43)
Query Neighborhood Hits	69	Target Neighborhood Hits	119	Shared Neighborhood Hits	6
SwissProt Accessions	P30658, O35731, Q8CIA0	Gene names	Cbx2, M33
Domain Architecture
Description	Chromobox protein homolog 2 (Modifier 3 protein) (M33).

DC1I2_HUMAN
θ value	5.27518 (rank : 44)	NC score	0.013693 (rank : 50)
Query Neighborhood Hits	69	Target Neighborhood Hits	201	Shared Neighborhood Hits	3
SwissProt Accessions	Q13409, Q96NG7, Q96S87, Q9BXZ5, Q9NT58	Gene names	DYNC1I2, DNCI2, DNCIC2
Domain Architecture
Description	Cytoplasmic dynein 1 intermediate chain 2 (Dynein intermediate chain 2, cytosolic) (DH IC-2) (Cytoplasmic dynein intermediate chain 2).

NEDD4_MOUSE
θ value	5.27518 (rank : 45)	NC score	0.007806 (rank : 62)
Query Neighborhood Hits	69	Target Neighborhood Hits	212	Shared Neighborhood Hits	3
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

PIWL4_MOUSE
θ value	5.27518 (rank : 46)	NC score	0.012987 (rank : 52)
Query Neighborhood Hits	69	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CGT6, Q8CC75	Gene names	Piwil4, Miwi2
Domain Architecture	No domain graphic available
Description	Piwi-like protein 4 (mAgo5).

SIAL_HUMAN
θ value	5.27518 (rank : 47)	NC score	0.029985 (rank : 33)
Query Neighborhood Hits	69	Target Neighborhood Hits	77	Shared Neighborhood Hits	4
SwissProt Accessions	P21815	Gene names	IBSP, BNSP
Domain Architecture
Description	Bone sialoprotein-2 precursor (Bone sialoprotein II) (BSP II) (Cell- binding sialoprotein) (Integrin-binding sialoprotein).

TRDN_HUMAN
θ value	5.27518 (rank : 48)	NC score	0.022018 (rank : 41)
Query Neighborhood Hits	69	Target Neighborhood Hits	542	Shared Neighborhood Hits	13
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

ZN384_HUMAN
θ value	5.27518 (rank : 49)	NC score	-0.000212 (rank : 69)
Query Neighborhood Hits	69	Target Neighborhood Hits	764	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TF68, O15407, Q8N938	Gene names	ZNF384, CAGH1, CIZ, NMP4
Domain Architecture	No domain graphic available
Description	Zinc finger protein 384 (Nuclear matrix transcription factor 4) (Nuclear matrix protein 4) (CAG repeat protein 1) (CAS-interacting zinc finger protein).

CSKI1_MOUSE
θ value	6.88961 (rank : 50)	NC score	0.004010 (rank : 67)
Query Neighborhood Hits	69	Target Neighborhood Hits	1031	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

DNL4_MOUSE
θ value	6.88961 (rank : 51)	NC score	0.016384 (rank : 47)
Query Neighborhood Hits	69	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BTF7, Q3UG76	Gene names	Lig4
Domain Architecture	No domain graphic available
Description	DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4).

DSG2_HUMAN
θ value	6.88961 (rank : 52)	NC score	0.004167 (rank : 66)
Query Neighborhood Hits	69	Target Neighborhood Hits	192	Shared Neighborhood Hits	2
SwissProt Accessions	Q14126	Gene names	DSG2
Domain Architecture
Description	Desmoglein-2 precursor (HDGC).

DSPP_MOUSE
θ value	6.88961 (rank : 53)	NC score	0.031803 (rank : 30)
Query Neighborhood Hits	69	Target Neighborhood Hits	491	Shared Neighborhood Hits	14
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

RNPS1_HUMAN
θ value	6.88961 (rank : 54)	NC score	0.024523 (rank : 39)
Query Neighborhood Hits	69	Target Neighborhood Hits	285	Shared Neighborhood Hits	4
SwissProt Accessions	Q15287, O75308, Q8WY42, Q9NYG3	Gene names	RNPS1, LDC2
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2).

RNPS1_MOUSE
θ value	6.88961 (rank : 55)	NC score	0.024523 (rank : 40)
Query Neighborhood Hits	69	Target Neighborhood Hits	285	Shared Neighborhood Hits	4
SwissProt Accessions	Q99M28, Q3TMJ1, Q922H8	Gene names	Rnps1
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1.

CCD82_MOUSE
θ value	8.99809 (rank : 56)	NC score	0.016821 (rank : 46)
Query Neighborhood Hits	69	Target Neighborhood Hits	75	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PG04, Q3V462	Gene names	Ccdc82
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 82.

CENPB_HUMAN
θ value	8.99809 (rank : 57)	NC score	0.017665 (rank : 45)
Query Neighborhood Hits	69	Target Neighborhood Hits	133	Shared Neighborhood Hits	5
SwissProt Accessions	P07199	Gene names	CENPB
Domain Architecture
Description	Major centromere autoantigen B (Centromere protein B) (CENP-B).

CYLC1_HUMAN
θ value	8.99809 (rank : 58)	NC score	0.035173 (rank : 28)
Query Neighborhood Hits	69	Target Neighborhood Hits	408	Shared Neighborhood Hits	8
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

DMP1_HUMAN
θ value	8.99809 (rank : 59)	NC score	0.025443 (rank : 37)
Query Neighborhood Hits	69	Target Neighborhood Hits	491	Shared Neighborhood Hits	13
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

FOG1_MOUSE
θ value	8.99809 (rank : 60)	NC score	0.001942 (rank : 68)
Query Neighborhood Hits	69	Target Neighborhood Hits	1237	Shared Neighborhood Hits	7
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

GOGA3_MOUSE
θ value	8.99809 (rank : 61)	NC score	0.008151 (rank : 61)
Query Neighborhood Hits	69	Target Neighborhood Hits	1437	Shared Neighborhood Hits	17
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

KELL_HUMAN
θ value	8.99809 (rank : 62)	NC score	0.009942 (rank : 57)
Query Neighborhood Hits	69	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	P23276, Q96RS8, Q99885	Gene names	KEL
Domain Architecture
Description	Kell blood group glycoprotein (EC 3.4.24.-) (CD238 antigen).

MDR1_MOUSE
θ value	8.99809 (rank : 63)	NC score	0.004255 (rank : 65)
Query Neighborhood Hits	69	Target Neighborhood Hits	105	Shared Neighborhood Hits	2
SwissProt Accessions	P06795	Gene names	Abcb1, Abcb1b, Mdr1, Mdr1b, Pgy1, Pgy1-1
Domain Architecture
Description	Multidrug resistance protein 1 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1) (P-glycoprotein 1) (CD243 antigen).

MTMR3_HUMAN
θ value	8.99809 (rank : 64)	NC score	0.007162 (rank : 63)
Query Neighborhood Hits	69	Target Neighborhood Hits	163	Shared Neighborhood Hits	3
SwissProt Accessions	Q13615, Q9NYN5, Q9NYN6, Q9UDX6, Q9UEG3	Gene names	MTMR3, KIAA0371, ZFYVE10
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Zinc finger FYVE domain-containing protein 10).

MYH14_HUMAN
θ value	8.99809 (rank : 65)	NC score	0.006959 (rank : 64)
Query Neighborhood Hits	69	Target Neighborhood Hits	995	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

NRAP_MOUSE
θ value	8.99809 (rank : 66)	NC score	0.010875 (rank : 55)
Query Neighborhood Hits	69	Target Neighborhood Hits	167	Shared Neighborhood Hits	5
SwissProt Accessions	Q80XB4, O35884, Q3UTY7, Q3UU10, Q80V40	Gene names	Nrap
Domain Architecture	No domain graphic available
Description	Nebulin-related anchoring protein (N-RAP).

PCLO_HUMAN
θ value	8.99809 (rank : 67)	NC score	0.010080 (rank : 56)
Query Neighborhood Hits	69	Target Neighborhood Hits	2046	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

RECQ4_MOUSE
θ value	8.99809 (rank : 68)	NC score	0.011593 (rank : 54)
Query Neighborhood Hits	69	Target Neighborhood Hits	206	Shared Neighborhood Hits	4
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

TOB1_MOUSE
θ value	8.99809 (rank : 69)	NC score	0.011705 (rank : 53)
Query Neighborhood Hits	69	Target Neighborhood Hits	48	Shared Neighborhood Hits	2
SwissProt Accessions	Q61471	Gene names	Tob1, Tob, Trob
Domain Architecture
Description	Tob1 protein (Transducer of erbB-2 1).

Hits sorted by NC score

SENP6_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	69	Target Neighborhood Hits	69	Shared Neighborhood Hits	69
SwissProt Accessions	Q9GZR1, O94891, Q8TBY4, Q9UJV5	Gene names	SENP6, KIAA0797, SSP1, SUSP1
Domain Architecture
Description	Sentrin-specific protease 6 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP6) (SUMO-1-specific protease 1).

SENP7_HUMAN
NC score	0.771824 (rank : 2)	θ value	1.08223e-53 (rank : 2)
Query Neighborhood Hits	69	Target Neighborhood Hits	97	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BQF6, Q96PS5, Q9C0F6, Q9HBT5	Gene names	SENP7, KIAA1707, SSP2, SUSP2
Domain Architecture
Description	Sentrin-specific protease 7 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP7) (SUMO-1-specific protease 2).

SENP2_MOUSE
NC score	0.556761 (rank : 3)	θ value	3.18553e-13 (rank : 3)
Query Neighborhood Hits	69	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	Q91ZX6, Q544T8, Q9D4Z0	Gene names	Senp2, Smt3ip2
Domain Architecture
Description	Sentrin-specific protease 2 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP2) (SUMO-1/Smt3-specific isopeptidase 2) (Smt3ip2) (Axam2).

SENP1_HUMAN
NC score	0.553209 (rank : 4)	θ value	3.52202e-12 (rank : 4)
Query Neighborhood Hits	69	Target Neighborhood Hits	38	Shared Neighborhood Hits	11
SwissProt Accessions	Q9P0U3, Q86XC8	Gene names	SENP1
Domain Architecture
Description	Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1).

SENP1_MOUSE
NC score	0.549693 (rank : 5)	θ value	7.84624e-12 (rank : 5)
Query Neighborhood Hits	69	Target Neighborhood Hits	40	Shared Neighborhood Hits	13
SwissProt Accessions	P59110	Gene names	Senp1
Domain Architecture
Description	Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1).

SENP2_HUMAN
NC score	0.547410 (rank : 6)	θ value	1.33837e-11 (rank : 6)
Query Neighborhood Hits	69	Target Neighborhood Hits	19	Shared Neighborhood Hits	9
SwissProt Accessions	Q9HC62, Q96SR2, Q9P2L5	Gene names	SENP2, KIAA1331
Domain Architecture
Description	Sentrin-specific protease 2 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP2) (SMT3-specific isopeptidase 2) (Smt3ip2) (Axam2).

SENP5_HUMAN
NC score	0.489656 (rank : 7)	θ value	3.41135e-07 (rank : 9)
Query Neighborhood Hits	69	Target Neighborhood Hits	37	Shared Neighborhood Hits	12
SwissProt Accessions	Q96HI0, Q96SA5	Gene names	SENP5
Domain Architecture
Description	Sentrin-specific protease 5 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP5).

SENP3_HUMAN
NC score	0.481334 (rank : 8)	θ value	2.61198e-07 (rank : 7)
Query Neighborhood Hits	69	Target Neighborhood Hits	38	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H4L4, Q96PS4, Q9Y3W9	Gene names	SENP3, SSP3, SUSP3
Domain Architecture
Description	Sentrin-specific protease 3 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP3) (SUMO-1-specific protease 3).

SENP3_MOUSE
NC score	0.479389 (rank : 9)	θ value	2.61198e-07 (rank : 8)
Query Neighborhood Hits	69	Target Neighborhood Hits	44	Shared Neighborhood Hits	11
SwissProt Accessions	Q9EP97	Gene names	Senp3, Smt3ip, Smt3ip1
Domain Architecture
Description	Sentrin-specific protease 3 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP3) (SUMO-1-specific protease 3) (Smt3-specific isopeptidase 1) (Smt3ip1).

SENP8_HUMAN
NC score	0.152415 (rank : 10)	θ value	0.279714 (rank : 13)
Query Neighborhood Hits	69	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	Q96LD8, Q96QA4	Gene names	SENP8, DEN1, NEDP1, PRSC2
Domain Architecture
Description	Sentrin-specific protease 8 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP8) (Protease, cysteine 2) (NEDD8-specific protease 1) (Deneddylase-1).

SENP8_MOUSE
NC score	0.127520 (rank : 11)	θ value	3.0926 (rank : 38)
Query Neighborhood Hits	69	Target Neighborhood Hits	9	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D2Z4, Q543P0	Gene names	Senp8, Den1, Nedp1
Domain Architecture
Description	Sentrin-specific protease 8 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP8) (NEDD8-specific protease 1) (Deneddylase-1).

VPS72_MOUSE
NC score	0.078308 (rank : 12)	θ value	0.47712 (rank : 17)
Query Neighborhood Hits	69	Target Neighborhood Hits	286	Shared Neighborhood Hits	12
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

VPS72_HUMAN
NC score	0.077842 (rank : 13)	θ value	0.47712 (rank : 16)
Query Neighborhood Hits	69	Target Neighborhood Hits	274	Shared Neighborhood Hits	11
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

MEPE_HUMAN
NC score	0.064754 (rank : 14)	θ value	0.813845 (rank : 20)
Query Neighborhood Hits	69	Target Neighborhood Hits	105	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NQ76	Gene names	MEPE
Domain Architecture
Description	Matrix extracellular phosphoglycoprotein precursor (Osteoblast/osteocyte factor 45) (OF45).

CCD22_MOUSE
NC score	0.058947 (rank : 15)	θ value	0.47712 (rank : 15)
Query Neighborhood Hits	69	Target Neighborhood Hits	268	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JIG7, Q8BYH4	Gene names	Ccdc22, DXImx40e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 22.

MAP2_HUMAN
NC score	0.056885 (rank : 16)	θ value	0.0961366 (rank : 11)
Query Neighborhood Hits	69	Target Neighborhood Hits	348	Shared Neighborhood Hits	10
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

CCD22_HUMAN
NC score	0.055209 (rank : 17)	θ value	1.38821 (rank : 22)
Query Neighborhood Hits	69	Target Neighborhood Hits	242	Shared Neighborhood Hits	6
SwissProt Accessions	O60826	Gene names	CCDC22, CXorf37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 22.

AP2B_MOUSE
NC score	0.049070 (rank : 18)	θ value	2.36792 (rank : 28)
Query Neighborhood Hits	69	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q61313	Gene names	Tfap2b, Tcfap2b
Domain Architecture
Description	Transcription factor AP-2 beta (AP2-beta) (Activating enhancer-binding protein 2 beta).

AP2B_HUMAN
NC score	0.049069 (rank : 19)	θ value	2.36792 (rank : 27)
Query Neighborhood Hits	69	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q92481, Q5JYX6, Q9NQ63, Q9NU99, Q9UJI7, Q9Y214, Q9Y3K3	Gene names	TFAP2B
Domain Architecture
Description	Transcription factor AP-2 beta (AP2-beta) (Activating enhancer-binding protein 2 beta).

IF2P_HUMAN
NC score	0.047204 (rank : 20)	θ value	0.0736092 (rank : 10)
Query Neighborhood Hits	69	Target Neighborhood Hits	889	Shared Neighborhood Hits	16
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

AP2A_MOUSE
NC score	0.046947 (rank : 21)	θ value	3.0926 (rank : 35)
Query Neighborhood Hits	69	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	P34056, Q60740, Q60741, Q60742, Q60743, Q62067, Q62068, Q62069, Q91VX0, Q9CRY4	Gene names	Tfap2a, Ap2tf, Tcfap2a
Domain Architecture
Description	Transcription factor AP-2 alpha (AP2-alpha) (Activating enhancer- binding protein 2 alpha) (Activator protein 2) (AP-2).

AP2A_HUMAN
NC score	0.046898 (rank : 22)	θ value	3.0926 (rank : 34)
Query Neighborhood Hits	69	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	P05549, Q13777	Gene names	TFAP2A, AP2TF, TFAP2
Domain Architecture
Description	Transcription factor AP-2 alpha (AP2-alpha) (Activating enhancer- binding protein 2 alpha) (AP-2 transcription factor) (Activator protein 2) (AP-2).

PHAR2_HUMAN
NC score	0.046083 (rank : 23)	θ value	0.62314 (rank : 18)
Query Neighborhood Hits	69	Target Neighborhood Hits	208	Shared Neighborhood Hits	6
SwissProt Accessions	O75167, Q68DM2	Gene names	PHACTR2, C6orf56, KIAA0680
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 2.

CD014_HUMAN
NC score	0.041779 (rank : 24)	θ value	1.38821 (rank : 23)
Query Neighborhood Hits	69	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NC60, Q8N7L6, Q9BSQ9	Gene names	C4orf14
Domain Architecture	No domain graphic available
Description	Protein C4orf14.

DPOLZ_MOUSE
NC score	0.039699 (rank : 25)	θ value	2.36792 (rank : 30)
Query Neighborhood Hits	69	Target Neighborhood Hits	169	Shared Neighborhood Hits	6
SwissProt Accessions	Q61493, Q9JMD6, Q9QWX6	Gene names	Rev3l, Polz, Sez4
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Seizure-related protein 4).

NCOR1_HUMAN
NC score	0.039641 (rank : 26)	θ value	0.365318 (rank : 14)
Query Neighborhood Hits	69	Target Neighborhood Hits	577	Shared Neighborhood Hits	13
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

DPOLZ_HUMAN
NC score	0.038915 (rank : 27)	θ value	2.36792 (rank : 29)
Query Neighborhood Hits	69	Target Neighborhood Hits	200	Shared Neighborhood Hits	8
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

CYLC1_HUMAN
NC score	0.035173 (rank : 28)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	69	Target Neighborhood Hits	408	Shared Neighborhood Hits	8
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

AP3B2_MOUSE
NC score	0.034164 (rank : 29)	θ value	0.813845 (rank : 19)
Query Neighborhood Hits	69	Target Neighborhood Hits	246	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JME5, Q6QR53, Q8R1E5	Gene names	Ap3b2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain).

DSPP_MOUSE
NC score	0.031803 (rank : 30)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	69	Target Neighborhood Hits	491	Shared Neighborhood Hits	14
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

PHF14_HUMAN
NC score	0.031723 (rank : 31)	θ value	1.81305 (rank : 26)
Query Neighborhood Hits	69	Target Neighborhood Hits	447	Shared Neighborhood Hits	9
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

AMRP_HUMAN
NC score	0.031666 (rank : 32)	θ value	3.0926 (rank : 33)
Query Neighborhood Hits	69	Target Neighborhood Hits	126	Shared Neighborhood Hits	4
SwissProt Accessions	P30533	Gene names	LRPAP1, A2MRAP
Domain Architecture
Description	Alpha-2-macroglobulin receptor-associated protein precursor (Alpha-2- MRAP) (Low density lipoprotein receptor-related protein-associated protein 1) (RAP).

SIAL_HUMAN
NC score	0.029985 (rank : 33)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	69	Target Neighborhood Hits	77	Shared Neighborhood Hits	4
SwissProt Accessions	P21815	Gene names	IBSP, BNSP
Domain Architecture
Description	Bone sialoprotein-2 precursor (Bone sialoprotein II) (BSP II) (Cell- binding sialoprotein) (Integrin-binding sialoprotein).

FA50A_HUMAN
NC score	0.029918 (rank : 34)	θ value	3.0926 (rank : 36)
Query Neighborhood Hits	69	Target Neighborhood Hits	264	Shared Neighborhood Hits	8
SwissProt Accessions	Q14320, Q5HY37	Gene names	FAM50A, DXS9928E, HXC26, XAP5
Domain Architecture
Description	Protein FAM50A (Protein XAP-5) (Protein HXC-26).

CCNB3_MOUSE
NC score	0.028124 (rank : 35)	θ value	1.81305 (rank : 25)
Query Neighborhood Hits	69	Target Neighborhood Hits	211	Shared Neighborhood Hits	9
SwissProt Accessions	Q810T2, Q810T3, Q8VDC8	Gene names	Ccnb3, Cycb3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

FA50A_MOUSE
NC score	0.027231 (rank : 36)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	69	Target Neighborhood Hits	293	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WV03, Q9D866	Gene names	Fam50a, D0HXS9928E, Xap5
Domain Architecture
Description	Protein FAM50A (XAP-5 protein).

DMP1_HUMAN
NC score	0.025443 (rank : 37)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	69	Target Neighborhood Hits	491	Shared Neighborhood Hits	13
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

PHF14_MOUSE
NC score	0.025415 (rank : 38)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	69	Target Neighborhood Hits	342	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

RNPS1_HUMAN
NC score	0.024523 (rank : 39)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	69	Target Neighborhood Hits	285	Shared Neighborhood Hits	4
SwissProt Accessions	Q15287, O75308, Q8WY42, Q9NYG3	Gene names	RNPS1, LDC2
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2).

RNPS1_MOUSE
NC score	0.024523 (rank : 40)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	69	Target Neighborhood Hits	285	Shared Neighborhood Hits	4
SwissProt Accessions	Q99M28, Q3TMJ1, Q922H8	Gene names	Rnps1
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1.

TRDN_HUMAN
NC score	0.022018 (rank : 41)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	69	Target Neighborhood Hits	542	Shared Neighborhood Hits	13
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

AR13B_HUMAN
NC score	0.020891 (rank : 42)	θ value	1.81305 (rank : 24)
Query Neighborhood Hits	69	Target Neighborhood Hits	528	Shared Neighborhood Hits	14
SwissProt Accessions	Q3SXY8, Q504W8	Gene names	ARL13B, ARL2L1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 2-like 1) (ARL2-like protein 1).

CBX2_MOUSE
NC score	0.018697 (rank : 43)	θ value	5.27518 (rank : 43)
Query Neighborhood Hits	69	Target Neighborhood Hits	119	Shared Neighborhood Hits	6
SwissProt Accessions	P30658, O35731, Q8CIA0	Gene names	Cbx2, M33
Domain Architecture
Description	Chromobox protein homolog 2 (Modifier 3 protein) (M33).

DDX23_HUMAN
NC score	0.018047 (rank : 44)	θ value	0.279714 (rank : 12)
Query Neighborhood Hits	69	Target Neighborhood Hits	486	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

CENPB_HUMAN
NC score	0.017665 (rank : 45)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	69	Target Neighborhood Hits	133	Shared Neighborhood Hits	5
SwissProt Accessions	P07199	Gene names	CENPB
Domain Architecture
Description	Major centromere autoantigen B (Centromere protein B) (CENP-B).

CCD82_MOUSE
NC score	0.016821 (rank : 46)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	69	Target Neighborhood Hits	75	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PG04, Q3V462	Gene names	Ccdc82
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 82.

DNL4_MOUSE
NC score	0.016384 (rank : 47)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	69	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BTF7, Q3UG76	Gene names	Lig4
Domain Architecture	No domain graphic available
Description	DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4).

NFM_MOUSE
NC score	0.014411 (rank : 48)	θ value	2.36792 (rank : 32)
Query Neighborhood Hits	69	Target Neighborhood Hits	1159	Shared Neighborhood Hits	20
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

BPA1_MOUSE
NC score	0.014253 (rank : 49)	θ value	1.38821 (rank : 21)
Query Neighborhood Hits	69	Target Neighborhood Hits	1477	Shared Neighborhood Hits	21
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

DC1I2_HUMAN
NC score	0.013693 (rank : 50)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	69	Target Neighborhood Hits	201	Shared Neighborhood Hits	3
SwissProt Accessions	Q13409, Q96NG7, Q96S87, Q9BXZ5, Q9NT58	Gene names	DYNC1I2, DNCI2, DNCIC2
Domain Architecture
Description	Cytoplasmic dynein 1 intermediate chain 2 (Dynein intermediate chain 2, cytosolic) (DH IC-2) (Cytoplasmic dynein intermediate chain 2).

NFM_HUMAN
NC score	0.013247 (rank : 51)	θ value	2.36792 (rank : 31)
Query Neighborhood Hits	69	Target Neighborhood Hits	1328	Shared Neighborhood Hits	23
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

PIWL4_MOUSE
NC score	0.012987 (rank : 52)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	69	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CGT6, Q8CC75	Gene names	Piwil4, Miwi2
Domain Architecture	No domain graphic available
Description	Piwi-like protein 4 (mAgo5).

TOB1_MOUSE
NC score	0.011705 (rank : 53)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	69	Target Neighborhood Hits	48	Shared Neighborhood Hits	2
SwissProt Accessions	Q61471	Gene names	Tob1, Tob, Trob
Domain Architecture
Description	Tob1 protein (Transducer of erbB-2 1).

RECQ4_MOUSE
NC score	0.011593 (rank : 54)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	69	Target Neighborhood Hits	206	Shared Neighborhood Hits	4
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

NRAP_MOUSE
NC score	0.010875 (rank : 55)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	69	Target Neighborhood Hits	167	Shared Neighborhood Hits	5
SwissProt Accessions	Q80XB4, O35884, Q3UTY7, Q3UU10, Q80V40	Gene names	Nrap
Domain Architecture	No domain graphic available
Description	Nebulin-related anchoring protein (N-RAP).

PCLO_HUMAN
NC score	0.010080 (rank : 56)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	69	Target Neighborhood Hits	2046	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

KELL_HUMAN
NC score	0.009942 (rank : 57)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	69	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	P23276, Q96RS8, Q99885	Gene names	KEL
Domain Architecture
Description	Kell blood group glycoprotein (EC 3.4.24.-) (CD238 antigen).

BMP5_HUMAN
NC score	0.009526 (rank : 58)	θ value	4.03905 (rank : 39)
Query Neighborhood Hits	69	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	P22003, Q9H547, Q9NTM5	Gene names	BMP5
Domain Architecture
Description	Bone morphogenetic protein 5 precursor (BMP-5).

MYH14_MOUSE
NC score	0.008618 (rank : 59)	θ value	3.0926 (rank : 37)
Query Neighborhood Hits	69	Target Neighborhood Hits	1225	Shared Neighborhood Hits	12
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

ADA30_HUMAN
NC score	0.008518 (rank : 60)	θ value	5.27518 (rank : 42)
Query Neighborhood Hits	69	Target Neighborhood Hits	391	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

GOGA3_MOUSE
NC score	0.008151 (rank : 61)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	69	Target Neighborhood Hits	1437	Shared Neighborhood Hits	17
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

NEDD4_MOUSE
NC score	0.007806 (rank : 62)	θ value	5.27518 (rank : 45)
Query Neighborhood Hits	69	Target Neighborhood Hits	212	Shared Neighborhood Hits	3
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

MTMR3_HUMAN
NC score	0.007162 (rank : 63)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	69	Target Neighborhood Hits	163	Shared Neighborhood Hits	3
SwissProt Accessions	Q13615, Q9NYN5, Q9NYN6, Q9UDX6, Q9UEG3	Gene names	MTMR3, KIAA0371, ZFYVE10
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Zinc finger FYVE domain-containing protein 10).

MYH14_HUMAN
NC score	0.006959 (rank : 64)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	69	Target Neighborhood Hits	995	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MDR1_MOUSE
NC score	0.004255 (rank : 65)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	69	Target Neighborhood Hits	105	Shared Neighborhood Hits	2
SwissProt Accessions	P06795	Gene names	Abcb1, Abcb1b, Mdr1, Mdr1b, Pgy1, Pgy1-1
Domain Architecture
Description	Multidrug resistance protein 1 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1) (P-glycoprotein 1) (CD243 antigen).

DSG2_HUMAN
NC score	0.004167 (rank : 66)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	69	Target Neighborhood Hits	192	Shared Neighborhood Hits	2
SwissProt Accessions	Q14126	Gene names	DSG2
Domain Architecture
Description	Desmoglein-2 precursor (HDGC).

CSKI1_MOUSE
NC score	0.004010 (rank : 67)	θ value	6.88961 (rank : 50)
Query Neighborhood Hits	69	Target Neighborhood Hits	1031	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

FOG1_MOUSE
NC score	0.001942 (rank : 68)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	69	Target Neighborhood Hits	1237	Shared Neighborhood Hits	7
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

ZN384_HUMAN
NC score	-0.000212 (rank : 69)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	69	Target Neighborhood Hits	764	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TF68, O15407, Q8N938	Gene names	ZNF384, CAGH1, CIZ, NMP4
Domain Architecture	No domain graphic available
Description	Zinc finger protein 384 (Nuclear matrix transcription factor 4) (Nuclear matrix protein 4) (CAG repeat protein 1) (CAS-interacting zinc finger protein).