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Network neighborhood for query Sequence : SENP3_HUMAN

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SENP3_HUMAN
SwissProt Accessions	Q9H4L4, Q96PS4, Q9Y3W9	Gene names	SENP3, SSP3, SUSP3
Domain Architecture
Description	Sentrin-specific protease 3 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP3) (SUMO-1-specific protease 3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SENP3_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	Q9H4L4, Q96PS4, Q9Y3W9	Gene names	SENP3, SSP3, SUSP3
Domain Architecture
Description	Sentrin-specific protease 3 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP3) (SUMO-1-specific protease 3).

SENP3_MOUSE
θ value	0 (rank : 2)	NC score	0.995328 (rank : 2)
Query Neighborhood Hits	38	Target Neighborhood Hits	44	Shared Neighborhood Hits	22
SwissProt Accessions	Q9EP97	Gene names	Senp3, Smt3ip, Smt3ip1
Domain Architecture
Description	Sentrin-specific protease 3 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP3) (SUMO-1-specific protease 3) (Smt3-specific isopeptidase 1) (Smt3ip1).

SENP5_HUMAN
θ value	4.98072e-83 (rank : 3)	NC score	0.928583 (rank : 3)
Query Neighborhood Hits	38	Target Neighborhood Hits	37	Shared Neighborhood Hits	11
SwissProt Accessions	Q96HI0, Q96SA5	Gene names	SENP5
Domain Architecture
Description	Sentrin-specific protease 5 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP5).

SENP1_MOUSE
θ value	1.46607e-42 (rank : 4)	NC score	0.840283 (rank : 5)
Query Neighborhood Hits	38	Target Neighborhood Hits	40	Shared Neighborhood Hits	11
SwissProt Accessions	P59110	Gene names	Senp1
Domain Architecture
Description	Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1).

SENP1_HUMAN
θ value	4.2656e-42 (rank : 5)	NC score	0.844794 (rank : 4)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	11
SwissProt Accessions	Q9P0U3, Q86XC8	Gene names	SENP1
Domain Architecture
Description	Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1).

SENP2_HUMAN
θ value	2.26708e-35 (rank : 6)	NC score	0.817099 (rank : 7)
Query Neighborhood Hits	38	Target Neighborhood Hits	19	Shared Neighborhood Hits	9
SwissProt Accessions	Q9HC62, Q96SR2, Q9P2L5	Gene names	SENP2, KIAA1331
Domain Architecture
Description	Sentrin-specific protease 2 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP2) (SMT3-specific isopeptidase 2) (Smt3ip2) (Axam2).

SENP2_MOUSE
θ value	5.0505e-35 (rank : 7)	NC score	0.817770 (rank : 6)
Query Neighborhood Hits	38	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	Q91ZX6, Q544T8, Q9D4Z0	Gene names	Senp2, Smt3ip2
Domain Architecture
Description	Sentrin-specific protease 2 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP2) (SUMO-1/Smt3-specific isopeptidase 2) (Smt3ip2) (Axam2).

SENP6_HUMAN
θ value	2.61198e-07 (rank : 8)	NC score	0.481334 (rank : 8)
Query Neighborhood Hits	38	Target Neighborhood Hits	69	Shared Neighborhood Hits	11
SwissProt Accessions	Q9GZR1, O94891, Q8TBY4, Q9UJV5	Gene names	SENP6, KIAA0797, SSP1, SUSP1
Domain Architecture
Description	Sentrin-specific protease 6 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP6) (SUMO-1-specific protease 1).

SENP7_HUMAN
θ value	3.77169e-06 (rank : 9)	NC score	0.448861 (rank : 9)
Query Neighborhood Hits	38	Target Neighborhood Hits	97	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BQF6, Q96PS5, Q9C0F6, Q9HBT5	Gene names	SENP7, KIAA1707, SSP2, SUSP2
Domain Architecture
Description	Sentrin-specific protease 7 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP7) (SUMO-1-specific protease 2).

SENP8_HUMAN
θ value	0.00134147 (rank : 10)	NC score	0.275433 (rank : 10)
Query Neighborhood Hits	38	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	Q96LD8, Q96QA4	Gene names	SENP8, DEN1, NEDP1, PRSC2
Domain Architecture
Description	Sentrin-specific protease 8 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP8) (Protease, cysteine 2) (NEDD8-specific protease 1) (Deneddylase-1).

SENP8_MOUSE
θ value	0.0431538 (rank : 11)	NC score	0.231363 (rank : 11)
Query Neighborhood Hits	38	Target Neighborhood Hits	9	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D2Z4, Q543P0	Gene names	Senp8, Den1, Nedp1
Domain Architecture
Description	Sentrin-specific protease 8 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP8) (NEDD8-specific protease 1) (Deneddylase-1).

CABIN_HUMAN
θ value	0.163984 (rank : 12)	NC score	0.062942 (rank : 12)
Query Neighborhood Hits	38	Target Neighborhood Hits	490	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

ARHGC_MOUSE
θ value	0.62314 (rank : 13)	NC score	0.029186 (rank : 15)
Query Neighborhood Hits	38	Target Neighborhood Hits	344	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

BSN_MOUSE
θ value	1.06291 (rank : 14)	NC score	0.015972 (rank : 24)
Query Neighborhood Hits	38	Target Neighborhood Hits	2057	Shared Neighborhood Hits	16
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

MAP1A_HUMAN
θ value	1.38821 (rank : 15)	NC score	0.013677 (rank : 27)
Query Neighborhood Hits	38	Target Neighborhood Hits	1626	Shared Neighborhood Hits	9
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

SFR14_MOUSE
θ value	1.38821 (rank : 16)	NC score	0.031990 (rank : 14)
Query Neighborhood Hits	38	Target Neighborhood Hits	238	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CH09, Q6PG19, Q80UY8, Q8BY32, Q8CFM0	Gene names	Sfrs14
Domain Architecture	No domain graphic available
Description	Putative splicing factor, arginine/serine-rich 14 (Arginine/serine- rich-splicing factor 14).

ARHGC_HUMAN
θ value	2.36792 (rank : 17)	NC score	0.023544 (rank : 20)
Query Neighborhood Hits	38	Target Neighborhood Hits	351	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

CEL_HUMAN
θ value	3.0926 (rank : 18)	NC score	0.007431 (rank : 34)
Query Neighborhood Hits	38	Target Neighborhood Hits	896	Shared Neighborhood Hits	8
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

GR65_HUMAN
θ value	3.0926 (rank : 19)	NC score	0.018046 (rank : 22)
Query Neighborhood Hits	38	Target Neighborhood Hits	148	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BQQ3, Q8N272, Q96H42	Gene names	GORASP1, GRASP65
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 1 (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) (Golgi peripheral membrane protein p65) (Golgi phosphoprotein 5) (GOLPH5).

IWS1_MOUSE
θ value	3.0926 (rank : 20)	NC score	0.012192 (rank : 30)
Query Neighborhood Hits	38	Target Neighborhood Hits	1258	Shared Neighborhood Hits	12
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

CO7A1_HUMAN
θ value	4.03905 (rank : 21)	NC score	0.009230 (rank : 31)
Query Neighborhood Hits	38	Target Neighborhood Hits	807	Shared Neighborhood Hits	12
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

HPS6_MOUSE
θ value	4.03905 (rank : 22)	NC score	0.027200 (rank : 16)
Query Neighborhood Hits	38	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BLY7, Q8BML5, Q8CIA3	Gene names	Hps6, Ru
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 6 protein homolog (Ruby-eye protein) (Ru).

IL4RA_MOUSE
θ value	4.03905 (rank : 23)	NC score	0.035483 (rank : 13)
Query Neighborhood Hits	38	Target Neighborhood Hits	194	Shared Neighborhood Hits	5
SwissProt Accessions	P16382, O54690, Q60583, Q8CBW5	Gene names	Il4r, Il4ra
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (IL-4- binding protein) (IL4-BP)].

5NT1B_MOUSE
θ value	5.27518 (rank : 24)	NC score	0.015957 (rank : 25)
Query Neighborhood Hits	38	Target Neighborhood Hits	78	Shared Neighborhood Hits	4
SwissProt Accessions	Q91YE9, Q91Y48	Gene names	Nt5c1b, Airp
Domain Architecture
Description	Cytosolic 5'-nucleotidase 1B (EC 3.1.3.5) (Cytosolic 5'-nucleotidase IB) (cN1B) (cN-IB) (Autoimmune infertility-related protein).

CN004_MOUSE
θ value	5.27518 (rank : 25)	NC score	0.016494 (rank : 23)
Query Neighborhood Hits	38	Target Neighborhood Hits	105	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K3X4, Q3USE5, Q8BUS1, Q8C011	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf4 homolog.

CNKR2_HUMAN
θ value	5.27518 (rank : 26)	NC score	0.012286 (rank : 29)
Query Neighborhood Hits	38	Target Neighborhood Hits	197	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CO6A1_MOUSE
θ value	5.27518 (rank : 27)	NC score	0.007498 (rank : 33)
Query Neighborhood Hits	38	Target Neighborhood Hits	241	Shared Neighborhood Hits	4
SwissProt Accessions	Q04857	Gene names	Col6a1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

RIMB1_HUMAN
θ value	5.27518 (rank : 28)	NC score	0.006750 (rank : 35)
Query Neighborhood Hits	38	Target Neighborhood Hits	1479	Shared Neighborhood Hits	9
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SYFM_HUMAN
θ value	5.27518 (rank : 29)	NC score	0.026330 (rank : 17)
Query Neighborhood Hits	38	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	O95363, Q53F66, Q5TCS3, Q6FG29, Q9NPY7, Q9P062	Gene names	FARS2, FARS1
Domain Architecture	No domain graphic available
Description	Phenylalanyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.20) (Phenylalanine--tRNA ligase) (PheRS).

ZMY15_HUMAN
θ value	5.27518 (rank : 30)	NC score	0.022802 (rank : 21)
Query Neighborhood Hits	38	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H091	Gene names	ZMYND15
Domain Architecture	No domain graphic available
Description	Zinc finger MYND domain-containing protein 15.

NOTC4_MOUSE
θ value	6.88961 (rank : 31)	NC score	0.000742 (rank : 37)
Query Neighborhood Hits	38	Target Neighborhood Hits	872	Shared Neighborhood Hits	3
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

ZAR1_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.024193 (rank : 19)
Query Neighborhood Hits	38	Target Neighborhood Hits	163	Shared Neighborhood Hits	6
SwissProt Accessions	Q86SH2	Gene names	ZAR1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

ZN541_HUMAN
θ value	6.88961 (rank : 33)	NC score	0.013730 (rank : 26)
Query Neighborhood Hits	38	Target Neighborhood Hits	203	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H0D2, Q8NDK8	Gene names	ZNF541
Domain Architecture	No domain graphic available
Description	Zinc finger protein 541.

AATK_MOUSE
θ value	8.99809 (rank : 34)	NC score	0.000456 (rank : 38)
Query Neighborhood Hits	38	Target Neighborhood Hits	942	Shared Neighborhood Hits	6
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

BCL9_MOUSE
θ value	8.99809 (rank : 35)	NC score	0.008636 (rank : 32)
Query Neighborhood Hits	38	Target Neighborhood Hits	770	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

CT128_HUMAN
θ value	8.99809 (rank : 36)	NC score	0.013153 (rank : 28)
Query Neighborhood Hits	38	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BQN1, Q5JWN6, Q8N276	Gene names	C20orf128
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf128.

IL4RA_HUMAN
θ value	8.99809 (rank : 37)	NC score	0.026258 (rank : 18)
Query Neighborhood Hits	38	Target Neighborhood Hits	144	Shared Neighborhood Hits	5
SwissProt Accessions	P24394, Q96P01, Q9H181, Q9H182, Q9H183, Q9H184, Q9H185, Q9H186, Q9H187, Q9H188	Gene names	IL4R, 582J2.1, IL4RA
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)].

VASN_HUMAN
θ value	8.99809 (rank : 38)	NC score	0.002296 (rank : 36)
Query Neighborhood Hits	38	Target Neighborhood Hits	449	Shared Neighborhood Hits	4
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

Hits sorted by NC score

SENP3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	Q9H4L4, Q96PS4, Q9Y3W9	Gene names	SENP3, SSP3, SUSP3
Domain Architecture
Description	Sentrin-specific protease 3 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP3) (SUMO-1-specific protease 3).

SENP3_MOUSE
NC score	0.995328 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	38	Target Neighborhood Hits	44	Shared Neighborhood Hits	22
SwissProt Accessions	Q9EP97	Gene names	Senp3, Smt3ip, Smt3ip1
Domain Architecture
Description	Sentrin-specific protease 3 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP3) (SUMO-1-specific protease 3) (Smt3-specific isopeptidase 1) (Smt3ip1).

SENP5_HUMAN
NC score	0.928583 (rank : 3)	θ value	4.98072e-83 (rank : 3)
Query Neighborhood Hits	38	Target Neighborhood Hits	37	Shared Neighborhood Hits	11
SwissProt Accessions	Q96HI0, Q96SA5	Gene names	SENP5
Domain Architecture
Description	Sentrin-specific protease 5 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP5).

SENP1_HUMAN
NC score	0.844794 (rank : 4)	θ value	4.2656e-42 (rank : 5)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	11
SwissProt Accessions	Q9P0U3, Q86XC8	Gene names	SENP1
Domain Architecture
Description	Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1).

SENP1_MOUSE
NC score	0.840283 (rank : 5)	θ value	1.46607e-42 (rank : 4)
Query Neighborhood Hits	38	Target Neighborhood Hits	40	Shared Neighborhood Hits	11
SwissProt Accessions	P59110	Gene names	Senp1
Domain Architecture
Description	Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1).

SENP2_MOUSE
NC score	0.817770 (rank : 6)	θ value	5.0505e-35 (rank : 7)
Query Neighborhood Hits	38	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	Q91ZX6, Q544T8, Q9D4Z0	Gene names	Senp2, Smt3ip2
Domain Architecture
Description	Sentrin-specific protease 2 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP2) (SUMO-1/Smt3-specific isopeptidase 2) (Smt3ip2) (Axam2).

SENP2_HUMAN
NC score	0.817099 (rank : 7)	θ value	2.26708e-35 (rank : 6)
Query Neighborhood Hits	38	Target Neighborhood Hits	19	Shared Neighborhood Hits	9
SwissProt Accessions	Q9HC62, Q96SR2, Q9P2L5	Gene names	SENP2, KIAA1331
Domain Architecture
Description	Sentrin-specific protease 2 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP2) (SMT3-specific isopeptidase 2) (Smt3ip2) (Axam2).

SENP6_HUMAN
NC score	0.481334 (rank : 8)	θ value	2.61198e-07 (rank : 8)
Query Neighborhood Hits	38	Target Neighborhood Hits	69	Shared Neighborhood Hits	11
SwissProt Accessions	Q9GZR1, O94891, Q8TBY4, Q9UJV5	Gene names	SENP6, KIAA0797, SSP1, SUSP1
Domain Architecture
Description	Sentrin-specific protease 6 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP6) (SUMO-1-specific protease 1).

SENP7_HUMAN
NC score	0.448861 (rank : 9)	θ value	3.77169e-06 (rank : 9)
Query Neighborhood Hits	38	Target Neighborhood Hits	97	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BQF6, Q96PS5, Q9C0F6, Q9HBT5	Gene names	SENP7, KIAA1707, SSP2, SUSP2
Domain Architecture
Description	Sentrin-specific protease 7 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP7) (SUMO-1-specific protease 2).

SENP8_HUMAN
NC score	0.275433 (rank : 10)	θ value	0.00134147 (rank : 10)
Query Neighborhood Hits	38	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	Q96LD8, Q96QA4	Gene names	SENP8, DEN1, NEDP1, PRSC2
Domain Architecture
Description	Sentrin-specific protease 8 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP8) (Protease, cysteine 2) (NEDD8-specific protease 1) (Deneddylase-1).

SENP8_MOUSE
NC score	0.231363 (rank : 11)	θ value	0.0431538 (rank : 11)
Query Neighborhood Hits	38	Target Neighborhood Hits	9	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D2Z4, Q543P0	Gene names	Senp8, Den1, Nedp1
Domain Architecture
Description	Sentrin-specific protease 8 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP8) (NEDD8-specific protease 1) (Deneddylase-1).

CABIN_HUMAN
NC score	0.062942 (rank : 12)	θ value	0.163984 (rank : 12)
Query Neighborhood Hits	38	Target Neighborhood Hits	490	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

IL4RA_MOUSE
NC score	0.035483 (rank : 13)	θ value	4.03905 (rank : 23)
Query Neighborhood Hits	38	Target Neighborhood Hits	194	Shared Neighborhood Hits	5
SwissProt Accessions	P16382, O54690, Q60583, Q8CBW5	Gene names	Il4r, Il4ra
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (IL-4- binding protein) (IL4-BP)].

SFR14_MOUSE
NC score	0.031990 (rank : 14)	θ value	1.38821 (rank : 16)
Query Neighborhood Hits	38	Target Neighborhood Hits	238	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CH09, Q6PG19, Q80UY8, Q8BY32, Q8CFM0	Gene names	Sfrs14
Domain Architecture	No domain graphic available
Description	Putative splicing factor, arginine/serine-rich 14 (Arginine/serine- rich-splicing factor 14).

ARHGC_MOUSE
NC score	0.029186 (rank : 15)	θ value	0.62314 (rank : 13)
Query Neighborhood Hits	38	Target Neighborhood Hits	344	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

HPS6_MOUSE
NC score	0.027200 (rank : 16)	θ value	4.03905 (rank : 22)
Query Neighborhood Hits	38	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BLY7, Q8BML5, Q8CIA3	Gene names	Hps6, Ru
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 6 protein homolog (Ruby-eye protein) (Ru).

SYFM_HUMAN
NC score	0.026330 (rank : 17)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	38	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	O95363, Q53F66, Q5TCS3, Q6FG29, Q9NPY7, Q9P062	Gene names	FARS2, FARS1
Domain Architecture	No domain graphic available
Description	Phenylalanyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.20) (Phenylalanine--tRNA ligase) (PheRS).

IL4RA_HUMAN
NC score	0.026258 (rank : 18)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	38	Target Neighborhood Hits	144	Shared Neighborhood Hits	5
SwissProt Accessions	P24394, Q96P01, Q9H181, Q9H182, Q9H183, Q9H184, Q9H185, Q9H186, Q9H187, Q9H188	Gene names	IL4R, 582J2.1, IL4RA
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)].

ZAR1_HUMAN
NC score	0.024193 (rank : 19)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	38	Target Neighborhood Hits	163	Shared Neighborhood Hits	6
SwissProt Accessions	Q86SH2	Gene names	ZAR1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

ARHGC_HUMAN
NC score	0.023544 (rank : 20)	θ value	2.36792 (rank : 17)
Query Neighborhood Hits	38	Target Neighborhood Hits	351	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ZMY15_HUMAN
NC score	0.022802 (rank : 21)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	38	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H091	Gene names	ZMYND15
Domain Architecture	No domain graphic available
Description	Zinc finger MYND domain-containing protein 15.

GR65_HUMAN
NC score	0.018046 (rank : 22)	θ value	3.0926 (rank : 19)
Query Neighborhood Hits	38	Target Neighborhood Hits	148	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BQQ3, Q8N272, Q96H42	Gene names	GORASP1, GRASP65
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 1 (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) (Golgi peripheral membrane protein p65) (Golgi phosphoprotein 5) (GOLPH5).

CN004_MOUSE
NC score	0.016494 (rank : 23)	θ value	5.27518 (rank : 25)
Query Neighborhood Hits	38	Target Neighborhood Hits	105	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K3X4, Q3USE5, Q8BUS1, Q8C011	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf4 homolog.

BSN_MOUSE
NC score	0.015972 (rank : 24)	θ value	1.06291 (rank : 14)
Query Neighborhood Hits	38	Target Neighborhood Hits	2057	Shared Neighborhood Hits	16
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

5NT1B_MOUSE
NC score	0.015957 (rank : 25)	θ value	5.27518 (rank : 24)
Query Neighborhood Hits	38	Target Neighborhood Hits	78	Shared Neighborhood Hits	4
SwissProt Accessions	Q91YE9, Q91Y48	Gene names	Nt5c1b, Airp
Domain Architecture
Description	Cytosolic 5'-nucleotidase 1B (EC 3.1.3.5) (Cytosolic 5'-nucleotidase IB) (cN1B) (cN-IB) (Autoimmune infertility-related protein).

ZN541_HUMAN
NC score	0.013730 (rank : 26)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	38	Target Neighborhood Hits	203	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H0D2, Q8NDK8	Gene names	ZNF541
Domain Architecture	No domain graphic available
Description	Zinc finger protein 541.

MAP1A_HUMAN
NC score	0.013677 (rank : 27)	θ value	1.38821 (rank : 15)
Query Neighborhood Hits	38	Target Neighborhood Hits	1626	Shared Neighborhood Hits	9
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

CT128_HUMAN
NC score	0.013153 (rank : 28)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	38	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BQN1, Q5JWN6, Q8N276	Gene names	C20orf128
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf128.

CNKR2_HUMAN
NC score	0.012286 (rank : 29)	θ value	5.27518 (rank : 26)
Query Neighborhood Hits	38	Target Neighborhood Hits	197	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

IWS1_MOUSE
NC score	0.012192 (rank : 30)	θ value	3.0926 (rank : 20)
Query Neighborhood Hits	38	Target Neighborhood Hits	1258	Shared Neighborhood Hits	12
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

CO7A1_HUMAN
NC score	0.009230 (rank : 31)	θ value	4.03905 (rank : 21)
Query Neighborhood Hits	38	Target Neighborhood Hits	807	Shared Neighborhood Hits	12
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

BCL9_MOUSE
NC score	0.008636 (rank : 32)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	38	Target Neighborhood Hits	770	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

CO6A1_MOUSE
NC score	0.007498 (rank : 33)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	38	Target Neighborhood Hits	241	Shared Neighborhood Hits	4
SwissProt Accessions	Q04857	Gene names	Col6a1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

CEL_HUMAN
NC score	0.007431 (rank : 34)	θ value	3.0926 (rank : 18)
Query Neighborhood Hits	38	Target Neighborhood Hits	896	Shared Neighborhood Hits	8
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

RIMB1_HUMAN
NC score	0.006750 (rank : 35)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	38	Target Neighborhood Hits	1479	Shared Neighborhood Hits	9
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

VASN_HUMAN
NC score	0.002296 (rank : 36)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	38	Target Neighborhood Hits	449	Shared Neighborhood Hits	4
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

NOTC4_MOUSE
NC score	0.000742 (rank : 37)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	38	Target Neighborhood Hits	872	Shared Neighborhood Hits	3
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

AATK_MOUSE
NC score	0.000456 (rank : 38)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	38	Target Neighborhood Hits	942	Shared Neighborhood Hits	6
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).